Life Sciences Commons^™

Simotang Oral Liquid Alleviates Functional Dyspepsia-Related Motility Dysfunction Through Ca²⁺-Dependent Smooth Muscle Contraction And Nrf2/Nf-Κb Modulation, Guo Mao, Chunxiang He, Jiaqin Liu, Dahua Wu, Puhua Zeng, Ye Mao

Journal of Food and Drug Analysis

Functional dyspepsia (FD) is a disorder of gut-brain interaction involving heterogeneous motor, sensory, immune, and oxidative stress-related mechanisms. Simotang oral liquid (SMT), a traditional Chinese medicine formulation used for dyspeptic and gastrointestinal motility-related symptoms, has not been evaluated with an integrated clinical, functional, and molecular framework. This single-arm prospective pre-post study assessed gastric emptying by the 13C-octanoic acid breath test, gastric electrical activity by electrogastrography, postprandial tolerance by nutrient drink testing, symptom scores, serum biomarkers, and gastric antral tissue markers in patients with FD. FD-like mice were used for charcoal meal transit, smooth muscle strip tension, calcium channel blockade, and …

Antibacterial Activity Of Galangin And Quercetin Against Multidrug Resistant Infections Of Gram Negative Bacteria From Patients Under Acute Myeloid Leukemia Conditions, Iraq, Mustafa Suhel Mustafa, Rana Mujahid Abdullah

Al-Bahir

Galangin and quercetin can be used as a promise route against infections of Gram negative bacteria (GNB) which recorded high incidence in patients with acute myeloid leukemia (AML) due to their immunocompromised state. This study assessed the antibacterial activity of galangin and quercetin against four species of GNB collected from AML patients by determining of sub-minimum inhibitory concentrations (sub-MICs) of these flavonoids. Then, the sub-MICs of both flavonoid agents were applied to evaluate their antibacterial effect on gene expression levels targeting four of porin encoding genes included ompK36 for Klebsiella pneumoniae, ompA for Escherichia coli, oprD2 for Pseudomonas …

Can Artificial Seagrass Meadows Reduce Pathogenic Bacteria In Coral Reef Ecosystems- A Mesocosm Study, Hewa Pathirannahelage Athri Thathsarani Weerakoon, Jimmy Kuo, Pi-Jen Liu, Kwee Siong Tew

Journal of Marine Science and Technology–Taiwan

Seagrass meadows provide essential coastal ecosystem functions by stabilizing sediments, enhancing water quality, and shaping nutrient and microbial dynamics. With global seagrass losses accelerating due to climate change and anthropogenic pressures, artificial seagrass (ASG) has been proposed as a nature-based alternative to mimic these functions. However, its ability to replicate biological interactions, particularly microbial regulation and pathogen suppression, remains unclear. In this study, we conducted a six-week mesocosm experiment comparing natural Thalassia hemprichii and ASG within coral reef-associated habitats in southern Taiwan. Physicochemical parameters, sedimentation rates, nutrient concentrations, and planktonic and benthic bacterial communities were analyzed. Sedimentation rates and nutrient …

Differential Equation Modeling For Sustainable Resource Management: A Steady-State Optimal Harvesting Approach, Iordanka N. Panayotova, Aleksei Talonov

CODEE Journal

Mathematical models based on differential equations provide a powerful framework for connecting real-world data to informed decision-making. In this work, we present a student-accessible project that uses an optimal-control framework to study the sustainable management of biological resources.

Motivated by fisheries management, we examine a predator--prey system in which harvesting decisions must balance ecological and economic considerations. The model is formulated as an optimal control problem that seeks to maximize the total discounted net revenue from harvesting. Rather than solving for the complete time-dependent harvesting trajectory, we restrict the analysis to positive controlled coexistence equilibria and characterize an interior stationary …

Spatiotemporal Variations Of Tidal Asymmetry Along The Coast Of Taiwan: Characteristics And Implications, Ting-Chieh Lin, Tai-Wen Hsu, Tzu-Chun Huang, Chun-Yuan Lin

Journal of Marine Science and Technology–Taiwan

This study presents the first systematic investigation into the spatiotemporal characteristics and evolutionary trends of tidal asymmetry along the coast of Taiwan from 2003 to 2022, employing a moving window method combined with the S_TIDE toolbox.  By quantifying the skewness of the Main Tidal Asymmetry Combinations (MTAC) and their temporal variations, the study reveals significant regional disparities between the eastern and western coasts.  The western coast is primarily dominated by the M2-M4 combination, with the northwestern region exhibiting a flood dominance pattern and the southwestern region characterized by ebb dominance.  Conversely, the eastern coast, attributed to its open topography and …

Reliable Performance Analysis Of Polyurea Coatings Used In Offshore Wind Turbines, Yu-Chang Lin, Yen-Fu Liu, I-Ming Pan, Ming-Yuan Lin, Kang-Yu Liao, Hung-Hua Sheu, Hung-Bin Lee

Journal of Marine Science and Technology–Taiwan

This study explores the weather resistance, mechanical properties and corrosion resistance of polyurea coatings in marine environments. The relevant analysis results can be used as a reliability assessment of offshore wind turbine structural coatings during their service life under the influence of marine environments. The long-term experiment uses seawater and 70°C thermal aging conditions as coating reliability assessment items. The microstructure of the samples that have been immersed in seawater for a long time and thermally aged is observed using a scanning electron microscope (SEM). The results show that the surface of the 100 and 125 series polyurea coatings is …

Identifying The Causality And Criticality Of Factors Influencing The Promotion Of Asian Island-Hopping Cruise Tourism In Taiwan, Hsiao-Chuan Liu, Gin-Shuh Liang, Feng-Ming Tsai, Yu-Ling Lien

Journal of Marine Science and Technology–Taiwan

Following the COVID-19 pandemic, the global tourism industry has steadily recovered since 2022. Island-hopping cruises have gained increasing attention for enhancing regional connectivity and diversifying marine travel experiences; however, their development in Asia remains limited compared with that in Europe and the Caribbean due to fragmented policy coordination, inadequate port infrastructure, and uneven technological readiness. Although Taiwan possesses a geographic advantage and can serve as a strategic hub linking Asian island destinations, systematic planning and stakeholder coordination remain insufficient, resulting in unclear mechanisms that drive or constrain island-hopping cruise tourism. Existing studies mainly focus on market demand or passenger behavior, …

White Shark Occurrence In Flower Garden Banks National Marine Sanctuary Revealed From Acoustic Telemetry In An Offshore Mpa, Michael A. Dance, Jay R. Rooker, R. J. David Wells, Megan V. Winton, Landes L. Randall, Marissa F. Nuttall, Brondum M. Krebs, Creed C. Branham, Brett B. Sweezey, Richard J. Kline

School of Earth, Environmental, & Marine Sciences Faculty Publications

The outer continental shelf of the Gulf of Mexico (Gulf) is characterized by unique bathymetric features that provide critical habitat for marine fauna. Here, we demonstrate the utility of large-scale acoustic telemetry for monitoring an oceanic marine protected area (MPA) and document the first known occurrences of white sharks (Carcharodon carcharias) within Flower Garden Banks National Marine Sanctuary (FGBNMS). White sharks were tagged with acoustic transmitters in the western North Atlantic Ocean off the east coast of the United States and Canada. Nine white sharks were detected along the outer shelf ecosystem associated with FGBNMS over a three-year …

Technical Analysis And Market Liquidity In Sale-And-Purchase Transactions Of Second-Hand Oil Tankers, Chih-Chung Cheng, Po-Yin Wang, Heng-Chih Chou

Journal of Marine Science and Technology–Taiwan

In addition to using second-hand oil tankers to fulfil immediate shipping needs, shipowners can leverage price fluctuations in the tanker market to make vessel sale-and-purchase (S&P) transactions. Given that the profitability of vessel S&P transactions depends primarily on timing decisions, in this study, technical analysis was applied to identify the optimal transaction timing for 5-, 10-, and 15-year-old second-hand Aframax tankers. In a simulation, an S&P strategy based on technical analysis outperformed a benchmark buy-and-hold strategy, particularly for newer tankers, possibly due to the higher price volatility and lower market efficiency in the markets for these vessels. However, the lack …

Synchronous Deep Reinforcement Learning For Optimized Storage Assignment Of Ship Blocks, Gawon Lee, Jaehyeon Heo, Misung Kim, Hyerim Bae

Journal of Marine Science and Technology–Taiwan

This paper presents a deep reinforcement learning (RL) framework for optimizing block storage allocation in shipbuilding yards. During the shipbuilding process, vessels are constructed in block units to maximize the operational efficiency. Following assembly, these blocks must be stored in limited yard spaces, creating a complex variant of the binary packing problem. This storage allocation problem is further complicated by operational constraints, including the barge capacity and transportation time restrictions. Moreover, poor storage decisions can lead to redundant block movements, which can adversely affect downstream processes and increase operational costs. To resolve this problem, a policy-gradient-based synchronous RL model was …

A Resilience Early Warning Assessment Of The Maritime Supply Chain: A Case Study Of China’S New Energy Vehicle Exports, Xiuqian Chen, Liangyong Chu, Mengyao Wang, Jiayin Du, Yiming Zhang, Xiyao Xu

Journal of Marine Science and Technology–Taiwan

Enhancing resilience through early warning is a critical strategy for mitigating disruption risks in the maritime supply chain (MSC). This study proposes a novel early warning assessment framework to determine the resilience of the MSC. It is referred to as a resilience early warning system. An evaluation index system for shipping enterprises is developed based on four dimensions: withstand capacity, adaptive capacity, learning capability, and the external environment. A resilience assessment model that uses the Bayesian best-worst method (BBWM) and the extension cloud model (ECM) is established to quantify MSC resilience. An early warning evaluation model based on a Bayesian …

Public-Port Throughput As An Activity Proxy For Near-Port Air Quality And Health: A Transferable Two-Scale Framework (Kaohsiung, 2017–2024), Ping-Jen Wang, Ying-Lin Hsu, Shih-Hao Chang, Bao-Tzung Wu

Journal of Marine Science and Technology–Taiwan

We developed a two-scale time series framework using monthly container throughput (20-foot equivalent units, TEU) as a port activity indicator. Applied to Kaohsiung, Taiwan (2017–2024), we related TEU to near-port NO₂ and PM₂.₅ (monthly) and air quality to outpatient respiratory diagnoses (weekly) across the 2019–2020 sulfur rules and the COVID-19 pandemic. Transfer-function models indicate TEU tends to lead near-port NO₂ by 6–9 months. Structural break tests at policy dates indicate nonsignificant changes in levels and slopes, suggesting gradual rather than abrupt shifts in the activity–pollution linkage. Weekly two-pollutant distributed-lag Poisson models estimated relative risks (lags 0–8) per interquartile range (IQR) …

Automated And Quantitative Characterization Of Benthic Habitat And Associated Biological Communities Of An Unknown Southeast Pacific Seamount, Yakufu Niyazi, Denise J. B. Swanborn, Jan M. Tapia-Guerra, Javier Sellanes, Erin E. Easton, Germán Zapata-Hernández, Heather A. Stewart, Alan J. Jamieson

School of Earth, Environmental, & Marine Sciences Faculty Publications

Seamounts are prominent seafloor features that strongly influence geological processes, ocean circulation, and benthic biodiversity. Despite their importance, most seamounts remain unmapped and poorly characterized, particularly in the southeast Pacific Ocean, a region recognized for high marine endemism and ecological isolation. In this study, we present a quantitative habitat characterization of a previously undocumented seamount, informally named Solito Seamount, located between the Nazca–Desventuradas Marine Park and the Juan Fernández Archipelago, within Chile’s Exclusive Economic Zone. The seamount is a conical volcanic edifice approximately 37 km wide, rising >3,500 m above the surrounding abyssal plain. High-resolution multibeam bathymetry and backscatter intensity …

Impacts Of Sprouted Barley On Performance And Carcass Ultrasound Measurements In Angus-Influenced Steers During Backgrounding, Zachary C. Crump, Anthony Fernando Alberto, Bailee L. Brown, Bryce W. Roholt, Lillian L. Okamoto, Ryan A. Spurling, Robert E. Ward, Brady M. Blackett, Robert L. Harding, Sanjeewa D. Ranathunga, Kara J. Thornton

Animal, Dairy, and Veterinary Science Faculty Publications

The objective of this research was to determine the impacts of including sprouted barley (SB) in the diets of backgrounding beef steers. Angus-influenced steers (328 ± 6.59 kg) were assigned to one of four diets (n = 15/diet): a control (CON) diet, or a diet containing 5%, 10%, or 20% SB (DM basis)—replacing corn silage and some rolled barley. Individual intake and feeding behavior were monitored using Vytelle bunks. Body weight (BW) and ruminal fluid samples were collected on d 0, 30, and 60, while dry matter intake (DMI), feeding behavior, average daily gain (ADG), and gain-to-feed ratio (G:F) were …

Exploring Evolution As A Unifying Theme In The General Biology For Majors Course Sequence, While Iteratively Examining Attitudes And Decisions About Learning: An Application Of Lonergan’S Transcendental Method, Christine E. Gray

San Jose - Lonergan Chair in Catholic Philosophy

As I reflect upon my journey as an educator, I recognize it has been shaped, in large part, by my own foundational roots in the Catholic Liberal Arts tradition. As I prepare for another academic year, I find myself, once again, considering how my pedagogical practice can better meet my students “where they are” in my General Biology for Majors I and II courses. Since that “place” is shaped by a student’s prior experiences, both in and out of the classroom, I also recognize that “place” is unique for each student. This is precisely why each term pushes me to …

A New Bubblegum Coral From The Nazca Ridge Reveals Chitin As The Structural Scaffold Of Skeleton-Less Paragorgia Colonies, Juan Armando Sánchez, Erin E. Easton, Nayeli Elizavet Garcia, Yony Román-Ochoa, Julia Kaled Cáceres, Javier Sellanes

School of Earth, Environmental, & Marine Sciences Faculty Publications

Bubblegum corals (Paragorgia; Corallidae) form among the largest branching colonies in deep-sea environments despite lacking an axial skeleton. How these octocorals maintain structural cohesion using only sub-millimeter sclerites has remained unexplained. Here we describe Paragorgia quitinosa Sánchez & Easton n. sp., collected at 670 m depth on the Nazca Ridge (southeastern Pacific) during the Schmidt Ocean Institute RV Falkor (too) expedition FKt240708, and report the first evidence of visible chitin in octocoral tissues. The new species is diagnosed by autozoids and siphonozoids retracted on prominent, rounded mounds, large 8-derived radiate capstan sclerites (mean 0.095 mm), and canal walls …

Integration Of Freshness Monitoring And Active Packaging Technologies For Aquatic Products, Maria Ali, Abdul Waheed Ghanghro, Bheem Raj Serani, Mahrukh Zakir

Journal of Food and Drug Analysis

Aquatic products are nutritionally valuable but highly perishable, with quality loss driven by microbial spoilage, biochemical changes, including total volatile basic nitrogen (TVB-N), trimethylamine (TMA) and histamine, and physicochemical deterioration, including lipid oxidation, gas production and texture loss. Conventional packaging slows these processes but does not report real-time freshness. This review analyzes how active packaging (antimicrobial, antioxidant, enzyme-inhibiting, and oxygen-scavenging systems, including bio- and nanocomposites) can be combined with freshness monitoring technologies (colorimetric/pH indicators, gas sensors, biosensors, and digital tools such as radio frequency identification (RFID) and Internet of Things (IoT) systems) specifically for fish, shrimp, and mollusks. We first …

High Tunnel Pollinators, Miranda L. Jones, Sheriden Hansen, Kelsey Graham, Robert Nelson Schaeffer, Brent Black

All Current Publications

High tunnels are used to extend the growing season. Unlike greenhouses, high tunnels are semi-permanent and not heated or cooled by a climate-control system. Instead, they use plastic sheeting to trap solar heat, allowing for season extension in temperate climates around spring and fall. Bee pollination can improve yields for several valuable crop species grown in high tunnels. Because high tunnels are largely enclosed, bees are typically released and managed within the structure. This fact sheet provides information on how to obtain and manage bee pollinators in high tunnels.

Field Guide To Common Plant Species Of Uinta Mountain Fens, Samantha Kurkowski, Blake Wellard, Karin M. Kettenring

All Current Publications

Fens are a unique class of wetland that host many specialized plant species globally and, in Utah, occur primarily in the Uinta Mountains. This guide provides an easy-to-use resource for amateurs and professionals who want to identify plants in fens. This guide includes key characteristics for identifying species, details on similar species and how to tell them apart, and information on habitat and frequency of occurrence. Species range from wetland obligates to upland plants that occasionally make their way into fens, with the purpose of including most species that may be encountered in a fen.

Hwi 20th Volume Milestone

Human–Wildlife Interactions

Human-Wildlife Interactions is entering a milestone volume in 2026.

A Target-Responsive And Signal-Amplified Dna Hydrogel Biosensor For Visual And Quantitative Detection Of Aflatoxin B1, Haojie Du, Haoyue Liu, Yongshuai Li, Shiyi Wei, Xinning Wang, Yunxuan Weng, Xiaoying Zhao

Journal of Food and Drug Analysis

Aflatoxin B1 (AFB1) poses a severe threat to food safety due to its potent carcinogenicity. To address the need for rapid and on-site detection, this study developed a colorimetric biosensor based on an AFB1-responsive DNA aptamer-cross-linked sodium alginate hydrogel. Gold nanoparticles (AuNPs) were encapsulated within the hydrogel as a visual signal reporter. The sensing mechanism relies on target-induced dissociation of aptamer crosslinkers, leading to hydrogel disintegration and release of AuNPs. The hydrogel formulation was optimized regarding sodium alginate concentration and crosslinking conditions. To enhance sensitivity, an Exonuclease I (Exo I)-triggered target recycling strategy was implemented, which amplifies hydrogel network disruption …

Developing A Deep Learning-Based Artificial Intelligence System For Detecting Scientific Misinformation On Digital Platforms, Shorouq Al-Awawdeh, Ayah Al- Jafari

Middle East Journal of Communication Studies

Objectives: This study develops and evaluates an Arabic scientific misinformation detection system by fine-tuning AraBERT-base-v2. It examines the effects of early stopping and input sequence length on model performance, interprets selected linguistic characteristics associated with misleading content, and discusses the limitations of using machine-translated data.

Methodology: The study adopted a mixed-methods design, employing a systematic integration of quantitative and qualitative approaches, supported by an interpretive qualitative reading. The initial database consisted of 23,546 records, including 123 Arabic articles collected from the Akeed, Sheek, and Taqeen platforms, and 23,423 foreign-language records drawn from the GossipCop and PolitiFact collections within FakeNewsNet. After …

Ddrr Acts As A Dna Damage-Induced Cell Division Inhibitor In Acinetobacter Baumannii, Christian P. Lowe, Deborah Cook, Lily Hoard, Mckinnley Martin, Janelle M. Hare

Acinetobacter baumannii DNA Damage Database

An article titled, "DdrR acts as a DNA damage-induced cell division inhibitor in Acinetobacter baumannii" published in the Journal of Bacteriology on September 9, 2026.

Broadening The Community Of Nudibranch Enthusiasts Through Multilingual Educational Programming To Increase Climate Advocacy Engagement, Richelle Li Tanner, Cintya Felix Mendivil, Ashley Lam, Lorena Muñoz, Micah Kim, Elena G. Morales Poot, Gabrielle Keeler-May

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Environmental literacy and advocacy for environmental protections are essential components of responsible stewardship. For coastal communities, stewardship requires knowledge of ocean processes and the biological communities living within these ecosystems. While many studies highlight difficulties in engaging American audiences in environmental concern and stewardship due to hyper-individualistic societal values, tidepooling is one recreational pathway to coastal community engagement that strengthens sense of place, and therefore, responsibility to protect natural resources. We sought to broaden the tidepooling community to include more diverse voices through a participatory science program with inland city-dwelling, multilingual, and non-English speaking adults. Using nudibranchs as an environmental …

Amorphous Calcium Phosphate Maintains Casein Microarchitecture While Modulating Bacterial Growth Kinetics, Vuk Uskoković, Michael Ibba, Lorenzo Eugenio Leiva

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Casein, the primary source of protein in ruminant milk, represents a family of proteins that self-assemble into globules composed of finer spherical subunits and stabilized by calcium phosphate (CP) nanoparticles. These globules act as holdase-type chaperones for unfolded or partially folded proteins, preventing their aggregation. Simultaneously, by integrating CP nanoparticles, they enable the bioavailability of calcium and phosphate beyond their solubility limits, thereby enhancing the nutritional value of milk. Using a range of physicochemical and biological characterization techniques, including scanning and transmission electron microscopy, organic and inorganic elemental analyses, SDS-PAGE, and vibrational, UV/Vis and NMR spectroscopies, it is demonstrated that …

Comparative Potency Testing Of Diphtheria Toxoid In Guinea Pigs And Mice For In-House Diphtheria-Tetanus-Pertussis And Diphtheria-Tetanus Vaccines, Wanlop Leeden, Supanee Ummalukacholk, Orawin Mangkhaladul, Eakachai Prompetchara

The Thai Journal of Pharmaceutical Sciences

Background: Diphtheria remains endemic in parts of Thailand and continues to threaten unvaccinated populations. To strengthen vaccine self-sufficiency, the Government Pharmaceutical Organization has developed in-house diphtheria–tetanus–pertussis (DTP) and diphtheria– tetanus (dT) vaccines. Potency testing of diphtheria toxoid is traditionally performed in guinea pigs; however, limitations in animal availability, cost, and logistics have prompted evaluation of alternative models.
Objectives: To compare diphtheria toxoid potency estimates of in-houseproduced DTP and dT vaccines using guinea pigs and mice, followed by a Vero cell-based toxin neutralization assay, and to assess the suitability of mice as an alternative model for potency testing.
Materials and Methods: …

Charge Modulation Of Peptide/Nucleic Acid Complexes: An Anionic Additive Enhances Gene Silencing And Crispr/Cas9 Editing By Promoting Intracellular Nucleic Acid Release, Abdulelah Alhazza, Sorour Khayyatnejad Shoushtari, Hasan Uludag, Keykavous Parang, Hamidreza Montazeri Aliabadi

Pharmacy Faculty Articles and Research

Introduction: Small interfering RNA (siRNA) and Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated Protein 9 (Cas9) complexes are effective approaches to temporarily downregulate protein expression via post-transcription RNA interference or permanently altering protein expression via editing genomic DNA, respectively. However, the efficient delivery of these mediators to targeted cells has been challenging, largely due to their anionic and hydrophilic nature, which hinders their interaction with the cell membrane and cellular internalization. Cell-penetrating peptides (CPPs) exhibit dual characteristics as a carrier for nucleic acid delivery, where positively charged components bind to the negatively charged nucleic acid, and the hydrophobic components …

Genomic Analysis Reveals New Subspecies Of Cercyonis Scudder, 1875 (Nymphalidae: Satyrinae: Satyrini), Jing Zhang, Qian Cong, Jinhui Shen, Leina Song, Todd L. Stout, Michael S. Fisher, Robb Hannawacker, Nick V. Grishin

The Taxonomic Report of the International Lepidoptera Survey

Genomic analysis of Cercyonis (Cercyonis) Scudder, 1875 (Nymphalidae Rafinesque, 1815) partitions the subgenus into three species groups and reveals five new subspecies from the USA (type localities in parentheses): Cercyonis (Cercyonis) pegala koosharem Stout and Grishin, ssp. n. (Utah, Sevier Co.), Cercyonis (Cercyonis) pegala lasala Grishin, M. Fisher, and Hannawacker ssp. n. (Utah, Grand Co.), Cercyonis (Cercyonis) pegala hortoni Grishin, ssp. n. (Arizona, Gila Co.), Cercyonis (Cercyonis) meadii maculana Grishin, ssp. n. (Colorado, Montezuma Co.), and Cercyonis (Cercyonis) meadii rimana Grishin, ssp. n. (Arizona, Yavapai Co.). A neotype is designated for Satyrus boopis Behr, 1864 (USA, California, Contra Costa Co.). …

Archives # 2 -- Thirty-Third And Third Degrees (1908), Editorial Board

The International Journal of Ecopsychology (IJE)

No abstract provided.

Archives # 1 -- A Soldier’S Home (1889), Editorial Board

The International Journal of Ecopsychology (IJE)

No abstract provided.