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Full-Text Articles in Life Sciences

Interactions Between Red Foxes And Coyotes Across Urban And Wild Habitats, Caroline E. Savage, Taylor S. Readyhough, Remington J. Moll, Jonathon D. Cepek Jan 2026

Interactions Between Red Foxes And Coyotes Across Urban And Wild Habitats, Caroline E. Savage, Taylor S. Readyhough, Remington J. Moll, Jonathon D. Cepek

UNH URC Open (2026 and after)

Dens are critical to the life history of many mammal species, particularly when raising young. Excavating a den is energetically costly, so several species can use existing dens, and multiple species may inhabit the same den complex simultaneously. However, the extent of den sharing among urban mammals is understudied. Between March 2021, and June 2023, we used camera traps to monitor a multi-species den site in Cleveland, Ohio, USA. We documented den visitation and use by at least 11 mammal species, including red fox, coyote, raccoon, woodchuck, and Virginia opossum. Coyotes and red foxes both exhibited scent-marking at the den …


Soil Organic Carbon And Soil Health Property Responses To Land Management Across Topographic Positions, Mia D. Makovsky Jan 2026

Soil Organic Carbon And Soil Health Property Responses To Land Management Across Topographic Positions, Mia D. Makovsky

All Graduate Theses, Dissertations, and Other Capstone Projects

uring the last ice age, ice sheets advanced and retreated across the upper Midwest, leaving behind a landscape characterized by poorly drained hummocky topography. Well-aerated soils have formed on uplands and lowlands are dominated by hydric soils. These wetlands and hydric soils have potential to store large quantities of carbon, particularly compared to the well-aerated uplands, but many have been drained and cultivated for decades. Conservation agriculture methods have emerged to protect and conserve soil health from negative effects due to cultivation.The purpose of this study is to determine how agricultural management practices and landscape properties (e.g, topographic position) affect …


Analyzing The Impact Of Sunscreen Pollutants On The Development Of Lytechinus Variegatus, Christina M. Lillenas, Chesney J. Anderson, Ann M. Buchmann Jan 2026

Analyzing The Impact Of Sunscreen Pollutants On The Development Of Lytechinus Variegatus, Christina M. Lillenas, Chesney J. Anderson, Ann M. Buchmann

Nebraska Academy of Sciences: Programs and Proceedings

Lytechinus variegatus or the variegated sea urchin is found in shallow, tropical waters. Lytechinus variegatus can be found in sandy reef beds, and sea grass, covered in algae and debris to protect itself from the UV rays and predators. Sea urchins play a crucial role in coral reef ecosystems. Sea urchins follow an omnivore diet, feeding on algae and phytoplankton. In coral reef ecosystems, sea urchins eat unwanted algae, allowing coral reefs to continue growing and thriving. Without the presence of sea urchins in coral reef communities, algae can negatively affect the growth and success of coral reefs. Sunscreen serves …


Inferring Genes And Biological Systems Under Selective Pressure In The Secondarily Temperate Cryonotothenioids, Esteban Cabrera Jan 2026

Inferring Genes And Biological Systems Under Selective Pressure In The Secondarily Temperate Cryonotothenioids, Esteban Cabrera

Theses, Dissertations and Culminating Projects

Notothenioid fishes represent one of the most compelling examples of adaptive radiation driven by extreme environmental change, having diversified in the chronically cold waters of the Southern Ocean. While most cryonotothenioids evolved highly specialized cold-adapted characteristics, several secondarily temperate species later re-invaded warmer environments. These lineages provide a rare opportunity to examine evolutionary reversibility and the genomic mechanisms enabling escape from extreme specialization. In this study, we investigate two secondarily temperate species, Dissostichus eleginoides and Champsocephalus esox, comparing their protein-coding orthogroups to background sets from Antarctic cryonotothenioids and basal temperate teleosts. Using phylogeny based evolutionary models (BUSTED, aBSREL, and RELAX) …


A Trajectory Of Zostera Marina (Eelgrass) Ecosystem Recovery: Pre- And Post-Hurricane Sandy Degradation In Barnegat Bay, New Jersey, Edgar A. Medina Jan 2026

A Trajectory Of Zostera Marina (Eelgrass) Ecosystem Recovery: Pre- And Post-Hurricane Sandy Degradation In Barnegat Bay, New Jersey, Edgar A. Medina

Theses, Dissertations and Culminating Projects

Hurricane Sandy struck Barnegat Bay, New Jersey in 2012 and obliterated the benthic marine ecosystem with extensive damage to Zostera marina meadows. Previous genetic assessments of Barnegat Bay Z. marina in 2008 revealed low heterozygosity and low connectivity between populations. The great disruption caused by Hurricane Sandy motivated us to investigate the long-term effects of the storm on the genetic condition of the eelgrass populations in the year 2021. The investigation revealed improvements in heterozygosity, inbreeding, and connectivity. These findings drove us to investigate the genetics of Barnegat Bay eelgrass populations in the intervening years of 2013 and 2017 with …


Patient Characteristics, Growth Indices, And Treatment Outcomes Among Children With Feeding Difficulties, Amelia Kearney Jan 2026

Patient Characteristics, Growth Indices, And Treatment Outcomes Among Children With Feeding Difficulties, Amelia Kearney

Theses, Dissertations and Culminating Projects

Pediatric feeding difficulties is an umbrella term that is used to describe children with a variety of problematic feeding behaviors and/or mealtime impairments that can impact age-appropriate food consumption, growth and the caregiver-child relationship. There is a lack of research from nutrition professionals regarding the nutrient intake, diet quality and growth outcomes among patients with pediatric feeding difficulties. Furthermore, changes in nutrient intakes during intensive outpatient treatment have not been formally assessed. PURPOSE: The purpose of Manuscript 1 was to describe the demographic profile, medical history, and baseline mealtime behaviors, usual diet, and diet quality of patients with feeding difficulties …


Risk Of Gestational Diabetes By Aerobic And Resistance Exercise During The First And Second Trimesters, Takaki Tanamoto, George Saade, Leryn J. Reynolds, Tetsuya Kawakita Jan 2026

Risk Of Gestational Diabetes By Aerobic And Resistance Exercise During The First And Second Trimesters, Takaki Tanamoto, George Saade, Leryn J. Reynolds, Tetsuya Kawakita

Department of Obstetrics & Gynecology Faculty Publications

Objective

While some studies have shown that exercise reduces the incidence of gestational diabetes mellitus (GDM), there is limited evidence on whether aerobic or resistance exercise is more beneficial. This study aimed to examine the rate of GDM according to the type of exercise during early pregnancy.

Study design

We analyzed data from the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be (nuMoM2b), a prospective cohort of individuals enrolled during the first and second trimesters. We excluded participants with pregestational diabetes or delivery < 20 weeks. The primary exposure was either aerobic or resistance exercises in the first or second trimester. For each trimester, the metabolic equivalent of task hours per week (MET-h/week) was calculated for each exercise. Participants were grouped as follows: "Aerobic exercise" (≥7.5 MET-h/week from aerobic exercises), "Resistance exercise" (≥2 times/week from resistance exercises), "Both types of exercise" (≥7.5 MET-h/week from aerobic exercise and ≥2 times/week from resistance exercises), and "Insufficient exercise" (≤7.5 MET-h/week from aerobic exercise and ≤2 times/week from resistance exercises). Our primary outcome was GDM. Adjusted relative risks (aRRs) with 95% confidence intervals (95% CIs) were calculated using modified Poisson regression, adjusting for potential confounders.

Results

In both the first and second trimesters, analyses included 9049 individuals. In the first trimester, individuals who performed …


Role Of Foxl2 Immunohistochemical Marker In Diagnosis Of Ovarian Sex Cord-Stromal Tumors, Correlation With Histopathologic Features And Inhibin Expression, Eman Magdi Hikal, Sylvia Albair Ashamallah, Nadia Abd El-Moniem Nada, Dina Abdallah Ibrahim Jan 2026

Role Of Foxl2 Immunohistochemical Marker In Diagnosis Of Ovarian Sex Cord-Stromal Tumors, Correlation With Histopathologic Features And Inhibin Expression, Eman Magdi Hikal, Sylvia Albair Ashamallah, Nadia Abd El-Moniem Nada, Dina Abdallah Ibrahim

Mansoura Medical Journal

Background: Ovarian Sex Cord-Stromal Tumors (SCST) are a broad category of rare neoplasms that exhibit diagnostic challenges. Alpha-inhibin has been traditionally used as immunohistochemical marker (IHC) for SCST, but restrictions as lack of specificity and variability of cytoplasmic staining evolved.  Forkhead box L2 (FOXL2) is one of the earliest markers of ovarian differentiation and is essential for the normal development of granulosa cells and has been identified to be a sensitive and specific marker of Sex Cord-Stromal differentiation.

Aim: Assess FOXL2-IHC expression in different types of SCSTs and correlate its expression with histopathological features and Inhibin-IHC.

Methods: …


Impact Of Body Mass Index On Clinical Outcomes In Metastatic Breast Cancer Running Title: Impact Of Bmi On Mbc Outcome, Alaa Abdelrahman Sonbol, Maha Elzaafarany, Ahmed Albehairy, Sherif Refaat Jan 2026

Impact Of Body Mass Index On Clinical Outcomes In Metastatic Breast Cancer Running Title: Impact Of Bmi On Mbc Outcome, Alaa Abdelrahman Sonbol, Maha Elzaafarany, Ahmed Albehairy, Sherif Refaat

Mansoura Medical Journal

Background: Body mass index (BMI) has been suggested as an important patient-related factor influencing treatment outcomes in breast cancer. This study aimed to evaluate the association between BMI categories and clinical outcomes among patients with metastatic breast cancer (MBC).

Patients and Methods: This retrospective study included 400 patients with MBC. Clinical outcomes assessed included response to first-line treatment, treatment-related toxicity, and status at last follow-up and BMI was calculated using the Quetelet index .

Results: Patients were characterized by a high prevalence of obesity and predominantly good performance status. Disease progression following first-line treatment was the most common …


Serum High Sensitivity Cardiac Troponin I Level And Its Relation To Severity Of Psoriasis Vulgaris, Aya Hassan Mohammed El-Shamy, Samia Mohammed Abdel Naby, Mohammed Fawzy El Sayed, Amany Ragab Youssef Ahmed Jan 2026

Serum High Sensitivity Cardiac Troponin I Level And Its Relation To Severity Of Psoriasis Vulgaris, Aya Hassan Mohammed El-Shamy, Samia Mohammed Abdel Naby, Mohammed Fawzy El Sayed, Amany Ragab Youssef Ahmed

Mansoura Medical Journal

Background: Psoriasis is a chronic inflammatory skin disease affecting 2.5% of the worldwide population. Troponin I levels are accompanied by cardiovascular disease (CVD) risk in psoriatic cases. So, this study was conducted to detect serum levels of high-sensitivity cardiac troponin I (HScTnI) in psoriasis vulgaris (PV) cases compared to healthy controls. Methods: This case-control study included 40 cases with PV and 40 healthy subjects as a control group. Disease severity evaluation was conducted by using the psoriasis area severity index (PASI) score to classify the cases into groups according to severity. Measurement of HScTnI levels was conducted. Results: Mean HsCTn …


Patellar Morphology In Primary Total Knee Arthroplasty Patients With Unexplained Pain, Mohammed Ahmed Abdelkhalek Abdelrazek, Adham Elsharkawey Elgeidi, Yasser Youssef Abdelrahman Abed, Kamel Mohamed Ahmed Ahmed Youssef Jan 2026

Patellar Morphology In Primary Total Knee Arthroplasty Patients With Unexplained Pain, Mohammed Ahmed Abdelkhalek Abdelrazek, Adham Elsharkawey Elgeidi, Yasser Youssef Abdelrahman Abed, Kamel Mohamed Ahmed Ahmed Youssef

Mansoura Medical Journal

Background: An effective surgical procedure for treating end-stage osteoarthritis of the knee (OA) is total knee arthroplasty (TKA). Pain is the main reason why many patients are still unhappy with their results following TKA. Patients who did TKA may experience anterior knee pain (AKP) with or without patellar resurfacing. Research has indicated that the morphology of the patella or trochlear geometry affects the stress on the patellofemoral joint.

Objective: To determine whether clinical scores and pain after TKA without patellar resurfacing were correlated with patellar shape. Methods: This retrospective case control study included 70 cases. We retrospectively assessed patients with …


Adnexal Magnetic Resonance (Adnex –Mr) Scoring System; A New Standardized Method For Characterization Of Adnexal Masses Inside Mansoura University Hospitals, Nora Diaa Ali Okab, Basma Elged, Sherif Abdel Fatah Moustafa, Sieza Samir, Yasser.M. Mesbah Jan 2026

Adnexal Magnetic Resonance (Adnex –Mr) Scoring System; A New Standardized Method For Characterization Of Adnexal Masses Inside Mansoura University Hospitals, Nora Diaa Ali Okab, Basma Elged, Sherif Abdel Fatah Moustafa, Sieza Samir, Yasser.M. Mesbah

Mansoura Medical Journal

Background Gynecologic masses are the most common subject of gynecologic imaging. The usefulness of MRI is high in the characterization of adnexal masses. The ADNEX MR classification framework was launched to stratify sonographically identified adnexal masses in to five groups based on their probability of malignancy: grade 1 (no lesion), grade 2 (benign), grade 3 (probably benign), grade 4 (indeterminate), and grade 5 (probably malignant). Aim to determine the accuracy of the ADNEX MR scoring system in classification of adnexal masses at Mansoura University Hospitals (MUH). Methods A total of 48 female patients with 52 adnexal masses on ultrasound were …


Effect Of Adenotonsillectomy On Nocturnal Enuresis In Children With Obstructive Sleeping Apnea, Ramla Dahir Hersi, Hossam El-Sayed Elsisi, Ahmed Abdoo Elzehzahy Jan 2026

Effect Of Adenotonsillectomy On Nocturnal Enuresis In Children With Obstructive Sleeping Apnea, Ramla Dahir Hersi, Hossam El-Sayed Elsisi, Ahmed Abdoo Elzehzahy

Mansoura Medical Journal

Background: Nocturnal enuresis (NE) is the involuntary passage of urine during sleep and is a common condition in the pediatric population. Obstructive sleep apnea (OSA), characterized by recurrent episodes of upper airway obstruction during sleep, has increasingly been identified as a significant contributing factor to NE. Previous studies indicate that children with OSA have a higher prevalence of bedwetting than their healthy counterparts.

Objective: To assess the impact of adenotonsillectomy (AT) on NE in children diagnosed with obstructive sleep apnea.

Methods: This prospective study enrolled 20 pediatric patients presenting with both NE and OSA secondary to severe adenotonsillar hypertrophy. Tonsillar …


Clinical And Dermoscopic Nail Changes In Patients With Chronic Kidney Disease: A Cross-Sectional Study, Ghada Nagy Mansour Borham, Hassan Abdel-Raheim Fayed, Eman Nagy Ahmed Abdelrazik, Amany Awad Mohamed Jan 2026

Clinical And Dermoscopic Nail Changes In Patients With Chronic Kidney Disease: A Cross-Sectional Study, Ghada Nagy Mansour Borham, Hassan Abdel-Raheim Fayed, Eman Nagy Ahmed Abdelrazik, Amany Awad Mohamed

Mansoura Medical Journal

Background: Nail abnormalities are commonly observed among patients with chronic kidney disease (CKD) and may reflect underlying systemic and metabolic alterations. Dermoscopy (Onychoscopy) has emerged as a valuable noninvasive tool for detecting subtle nail changes.

Aim:  To describe the patterns and dermoscopic features of nail changes in patients with chronic kidney disease (CKD) and to explore their association with disease severity and renal function parameters.

Methods: This cross-sectional descriptive study included 127 patients with different stages of CKD. All participants underwent a comprehensive clinical and dermoscopic evaluation of the nail apparatus. Dermoscopic findings included longitudinal ridging, white …


Whole Tumor Apparent Diffusion Coefficient Histogram In Assessment Of Treatment Response In Locally Advanced Cervical Cancer, Wahdan. N, Wahba. H, Samir. S, Dina. G. Abdelzaher Jan 2026

Whole Tumor Apparent Diffusion Coefficient Histogram In Assessment Of Treatment Response In Locally Advanced Cervical Cancer, Wahdan. N, Wahba. H, Samir. S, Dina. G. Abdelzaher

Mansoura Medical Journal

Purpose:

We aimed to determine the prognostic value of whole-tumor ADC histogram analysis in predicting therapeutic outcomes for patients undergoing concurrent chemoradiotherapy (CCRT) for locally advanced cervical cancer (LACC).

Methods:

This prospective, single-institution study enrolled 40 women (mean age 53.8 ± 11.4 years) with pathologically confirmed LACC (FIGO stages IIB–IVA). Pelvic MRI including diffusion-weighted imaging (DWI) was performed at baseline and after CCRT. Whole-tumor regions of interest (ROIs) were manually delineated on ADC maps to extract histogram parameters (mean, minimum, maximum ADC, skewness, and kurtosis). Using RECIST 1.1 criteria, patients were classified as responders (complete or partial response) or …


Use Of Thyroid Imaging Reporting And Data Systems (Tirads) Ultrasound In Differential Diagnosis Of Thyroid Nodules, Aya Mohamed Hamed Abdelaal, Ghada M Ahmed Gaballah, Donia Mohamed Sobh Jan 2026

Use Of Thyroid Imaging Reporting And Data Systems (Tirads) Ultrasound In Differential Diagnosis Of Thyroid Nodules, Aya Mohamed Hamed Abdelaal, Ghada M Ahmed Gaballah, Donia Mohamed Sobh

Mansoura Medical Journal

Background: Thyroid nodules refer to masses of abnormally proliferating cells with abnormal tissue stiffness in thyroid. This study aimed to assess diagnostic accuracy of Thyroid Imaging Reporting and Data System in differentiating benign from malignant thyroid nodules.

Methods: This cross-sectional study included forty adult patients with sixty-two thyroid nodules. A 7.5-10 MHz linear array transducer was used to perform imaging protocol. Three-dimensional measurements were done on nodules. All thyroid nodules were  examined using doppler ultrasound. All thyroid nodules were described in terms of composition, echogenicity, margins, shape and echogenic foci.  According to ACR TI-RADS,  the points were given …


Survivin And C-Reactive Protein Serum Levels In Acne Vulgaris Patients In Relation To Its Severity, Asmaa Ayman Gouda, Sara Hamdy Fouad, Hyam Sameh Nada, Hanan Ahmed Salem Jan 2026

Survivin And C-Reactive Protein Serum Levels In Acne Vulgaris Patients In Relation To Its Severity, Asmaa Ayman Gouda, Sara Hamdy Fouad, Hyam Sameh Nada, Hanan Ahmed Salem

Mansoura Medical Journal

Background: Acne vulgaris (AV) is a chronic inflammatory disease of the pilosebaceous unit with variable clinical severity. Increasing evidence suggests that acne may represent a localized inflammatory condition with potential systemic inflammatory involvement. Survivin, an inhibitor of apoptosis protein has been implicated in abnormal keratinocyte and sebocyte survival, while C-reactive protein (CRP) is a biomarker of systemic inflammation.

Aim of the study: To evaluate serum survivin and CRP levels in cases with AV compared to healthy controls and to assess their relationship with disease severity.

Subjects and methods: This case-control study included 45 patients with clinically diagnosed AV and 45 …


The Role Of Vitamin D In Management Of Pediatric Chronic Immune Thrombocytopenia, Eman Magdy Yahia, Suzy Abd El Mabood Abd El Hameed, Dalia Tawfeek Hussein, Amany Mamdouh Shoumah Jan 2026

The Role Of Vitamin D In Management Of Pediatric Chronic Immune Thrombocytopenia, Eman Magdy Yahia, Suzy Abd El Mabood Abd El Hameed, Dalia Tawfeek Hussein, Amany Mamdouh Shoumah

Mansoura Medical Journal

In children, immune thrombocytopenia (ITP) remains a serious health concern, which is an autoimmune disorder (AID) characterized by an isolated decrease in platelet count, leading to an increased risk of bleeding.

The use of vitamin D supplementation represents a turning point in many autoimmune diseases, with the potential to deliver high cure rates with fewer side effects than previous therapies. In this review, we explore the incidence of ITP , immunopathogenesis, diagnosis and management in pediatric patients. We will discuss the mechanisms of action of vitamin D , focusing on its role in autoimmune diseases especially ITP


The Prognostic Value Of Arterial Spin Labeling Mri In Middle Cerebral Artery Ischemic Stroke Patients Receiving Thrombolytic Therapy, Ahmed Effat Saied, Nihal Mohamed El-Batouty, Mohamed Abdel Salam Ali, Merehan Reda Abo Alnaga Jan 2026

The Prognostic Value Of Arterial Spin Labeling Mri In Middle Cerebral Artery Ischemic Stroke Patients Receiving Thrombolytic Therapy, Ahmed Effat Saied, Nihal Mohamed El-Batouty, Mohamed Abdel Salam Ali, Merehan Reda Abo Alnaga

Mansoura Medical Journal

Background: Reestablishing blood circulation to the brain represents the primary proven treatment goal for acute ischaemic stroke (AIS). Recombinant tissue plasminogen activator (r-TPA) is a thrombolytic medication that enhances the rate of arterial blood flow restoration, reestablishes tissue perfusion, and leads to better functional recovery. This research aimed to examine changes in regional brain perfusion identified through arterial spin labeling (ASL) and how these changes correlate with functional recovery following ischemic stroke. Methods: This prospective observational research included 50 subjects with AIS in the middle cerebral artery (MCA) territory who were eligible for r-TPA treatment. Each patient underwent comprehensive neurological …


Effect Of Graft Steatosis On The Early Outcome Of Living Donor Liver Transplantation, Kareem Maher Shams Eldeen Hassan, Ahmed Mahmoud Abdelrafee, Ahmed Mohamed Ibrahim Elsabbagh, Mohamed Abd Elwahab Ali Jan 2026

Effect Of Graft Steatosis On The Early Outcome Of Living Donor Liver Transplantation, Kareem Maher Shams Eldeen Hassan, Ahmed Mahmoud Abdelrafee, Ahmed Mohamed Ibrahim Elsabbagh, Mohamed Abd Elwahab Ali

Mansoura Medical Journal

Background

Hepatic steatosis in donor grafts represents a growing challenge in living donor liver transplantation (LDLT) due to the rising prevalence of metabolic syndrome. The impact of varying degrees of graft steatosis on recipient and donor outcomes remains incompletely defined.

Aim

To evaluate the effect of different degrees of graft steatosis on early postoperative outcomes in both recipients and donors following LDLT.

Methods

This retrospective study analyzed 169 LDLT cases performed at Mansoura University between January 2014 and June 2024. Donors aged 18-45 years with BMI≥5% on liver biopsy were included. Grafts were stratified by steatosis degree:20% (n=4). Primary outcome …


Outcome Of Conservative Management Of Placenta Accreta Spectrum In Mansoura University Hospital, Nasra Hassan Mohamed, Mohamed Mohamed Eltotongy, Maher Elesewi Kamel Elgaly Jan 2026

Outcome Of Conservative Management Of Placenta Accreta Spectrum In Mansoura University Hospital, Nasra Hassan Mohamed, Mohamed Mohamed Eltotongy, Maher Elesewi Kamel Elgaly

Mansoura Medical Journal

Background: Placenta accreta spectrum (PAS) represents a significant global health challenge, with its incidence rising in parallel with the increasing prevalence of cesarean sections (CS). While cesarean hysterectomy is traditionally considered the standard treatment, conservative management offers a fertility-preserving alternative in carefully selected cases. This study aimed to evaluate the safety and effectiveness of conservative treatment for PAS at Mansoura University Hospital over a two-year period.

Methods: This retrospective analytical study included 132 women diagnosed with placenta accreta who underwent conservative management. Patient data, including obstetric history, degree of accreta, bleeding episodes, timing of delivery, and the specific uterine-sparing technique …


Impact Of Covid-19 Infection On Left Ventricular Systolic And Diastolic Functions., Hazem Galal Mohamed, Maged Zaghloul Mohamed Amer, Aml Fathy Moustafa, Shady Hussein Mohamed Jan 2026

Impact Of Covid-19 Infection On Left Ventricular Systolic And Diastolic Functions., Hazem Galal Mohamed, Maged Zaghloul Mohamed Amer, Aml Fathy Moustafa, Shady Hussein Mohamed

Mansoura Medical Journal

Background: SARS-CoV-2, the pathogen behind COVID-19, often involves the cardiovascular system due to high ACE2 receptor density in myocardial tissue. While immediate cardiac complications are recognized, the persistent effects on left ventricular (LV) performance require further investigation through echocardiography.

Aim: This study aimed to comprehensively describe the sequelae of COVID-19 infection on the left ventricle using echocardiography

Methods: The study included 100 participants. Cardiac function was assessed using a standard 12-lead ECG and transthoracic echocardiography. LV systolic function was evaluated using the Biplane Simpson Method, and myocardial contractility was further analyzed using Speckle-Tracking Echocardiography (STE).

Results: The mean age was …


Effect Of Graft Weight On Splenic Volume After Living Donor Liver Transplant, Raghda Adel Mohammed, Amina Ahmed Sultan, Eman Mohammed Helmy, Mohamed Samy Habl Jan 2026

Effect Of Graft Weight On Splenic Volume After Living Donor Liver Transplant, Raghda Adel Mohammed, Amina Ahmed Sultan, Eman Mohammed Helmy, Mohamed Samy Habl

Mansoura Medical Journal

Background: In recipients of liver transplantation (LT), spleen volume reflects the portal hemodynamic status. Optimization of graft weight and studying its effect on the outcomes on the splenic volume after the transplant is one of the techniques for portal inflow modulation.  Aim: The study aims to assess the degree of splenic volume reduction after living donor liver transplantation in correlation to graft weight. Methods: The study analyzed 29 liver transplantation patients, involving comprehensive history taking, clinical examination, and laboratory data assessment. Spleen volume has been measured via a semi‑automatic region‑based technique with subsequent manual refinement when necessary to accurately delineate …


Prevalence And Outcome Of Splenic Injury Among Pediatric Trauma Patients, Omar Emad El-Din Bedair Hassan El-Nekity, Magdy Basheer, Amir A. Fikry, Mohamed Shetiwy Jan 2026

Prevalence And Outcome Of Splenic Injury Among Pediatric Trauma Patients, Omar Emad El-Din Bedair Hassan El-Nekity, Magdy Basheer, Amir A. Fikry, Mohamed Shetiwy

Mansoura Medical Journal

Background Pediatric trauma represents a critical public health issue, being the leading contributor of death and long-term disability in this age group. Blunt abdominal trauma is particularly common, with the spleen identified as the most frequently injured organ due to children's distinct anatomical traits. This study aims to detect morbidity, mortality, and complications resulting from splenic injuries in the pediatric population. Patients and methods This observational cross-sectional study was conducted at Mansoura University Emergency Hospital from September 2024 to September 2025. It included 104 pediatric patients with splenic injury out of 3600 pediatric trauma patients. Results The prevalence of splenic …


Predictive Value Of Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio And Ca-125 Dynamics After Neoadjuvant Chemotherapy For Surgical Outcomes And Prognosis In Ovarian Cancer, Asmaa S. Othman, Hend M. Serya, Manar H. Ahmed, Asmaa F. Elfayoumey Jan 2026

Predictive Value Of Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio And Ca-125 Dynamics After Neoadjuvant Chemotherapy For Surgical Outcomes And Prognosis In Ovarian Cancer, Asmaa S. Othman, Hend M. Serya, Manar H. Ahmed, Asmaa F. Elfayoumey

Mansoura Medical Journal

Background: The prognosis of patients with advanced-stage epithelial ovarian cancer (EOC) having debulking surgery is greatly influenced by optimal resection. Neutrophil-to-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and CA-125 values are examples of inflammatory markers that have been identified as possible predictive markers.

Objective: This study evaluated neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), and CA-125 dynamics as predictors of surgical outcomes and survival in advanced ovarian cancer patients receiving neoadjuvant chemotherapy (NACT).

Methods: We conducted a retrospective analysis of 171 patients treated at Mansoura University (2020-2025) with platinum-taxane neoadjuvant chemotherapy followed by interval debulking surgery (IDS). Pre- …


Role Of Positron Emission Tomography-Computed Tomography (Pet-Ct) In Evaluation Of Hepato-Cellular Carcinoma, Mona Baz, Ahmed Youssef Kandeel, Mohamed Ali El-Adalany, Dina El-Metwally Jan 2026

Role Of Positron Emission Tomography-Computed Tomography (Pet-Ct) In Evaluation Of Hepato-Cellular Carcinoma, Mona Baz, Ahmed Youssef Kandeel, Mohamed Ali El-Adalany, Dina El-Metwally

Mansoura Medical Journal

Background: Globally HCC appeared to be the third main reason of mortality associated with cancer.  According to degree of differentiation, HCC can be classified into four grades. PET/CT represents a functional imaging technique that offers metabolic insights into the tumor. It may play a substantial turn in prediction of biological behavior of HCC, predicting tumor grade and presence of microvascular invasion.

Aim of the work:  This work aimed to assess the utility of 18F-FDG PET/CT in identification of primary hepatocellular carcinoma (HCC) and in predicting its histological grade.

Methods: A total of 52 patients with established HCC were included in …


Patterns Of Bilirubin Decline After Biliary Stenting In Malignant Obstructive Jaundice, Omar Abdallah, Shymaa Abdelghany, Mohamad A. Ebrahim, Hassan Atalla Jan 2026

Patterns Of Bilirubin Decline After Biliary Stenting In Malignant Obstructive Jaundice, Omar Abdallah, Shymaa Abdelghany, Mohamad A. Ebrahim, Hassan Atalla

Mansoura Medical Journal

Background: Malignant extrahepatic biliary obstruction (MEBO) is a common cause of obstructive jaundice associated with high morbidity and mortality. ERCP-guided biliary drainage is widely used for palliative management, however, real-world data regarding bilirubin decline and predictors of success remain limited. This study aimed to evaluate bilirubin decline patterns, clinical outcomes, and predictors of clinical success following ERCP-guided biliary drainage in patients with MEBO.

Methods: This prospective observational study included consecutive MEBO patients who underwent ERCP-guided biliary drainage either by plastic or metallic stents at a tertiary-care hospital. Technical success, defined as successful stent placement, and clinical success, defined as symptomatic …


Clinical Outcomes Of Ultrasound-Guided Tmj Arthrocentesis In Post-Traumatic Internal Derangement: A Prospective Single-Arm Clinical Study, Ahmed Emad Mohamed Ghaly, Nabil Mokhtar Mohammed, Mohamed Radwan Elhadidy, Mohammed Hassan El Fahar Jan 2026

Clinical Outcomes Of Ultrasound-Guided Tmj Arthrocentesis In Post-Traumatic Internal Derangement: A Prospective Single-Arm Clinical Study, Ahmed Emad Mohamed Ghaly, Nabil Mokhtar Mohammed, Mohamed Radwan Elhadidy, Mohammed Hassan El Fahar

Mansoura Medical Journal

Background: The most common condition is temporomandibular joint (TMJ) internal derangement (ID). common TMJ disorder. It is defined as an abnormal displacement of the articular disc from its normal position relative to the condyle during joint function.

Aim: To evaluate the clinical outcomes of ultrasound-guided temporomandibular joint (TMJ) arthrocentesis in patients with post-traumatic internal derangement, the effectiveness of the procedure in reducing pain intensity, improving mandibular range of motion (maximum mouth opening and lateral excursions), decreasing TMJ clicking, and determining the overall clinical success rate over a 6-month follow up period.

Patients and methods: This prospective single-arm non-randomized study was …


Impact Of Early Injection Laryngoplasty On Voice Outcomes And Quality Of Life In Acute Unilateral Vocal Fold Paralysis, Abdelrhman Ali Kamal, M El-Kotb, Hemmat Mostafa Baz, Ahmed S. Abdelmeguid Jan 2026

Impact Of Early Injection Laryngoplasty On Voice Outcomes And Quality Of Life In Acute Unilateral Vocal Fold Paralysis, Abdelrhman Ali Kamal, M El-Kotb, Hemmat Mostafa Baz, Ahmed S. Abdelmeguid

Mansoura Medical Journal

Background

Unilateral vocal fold paralysis (UVFP) leads to glottic insufficiency, resulting in dysphonia, reduced vocal strength, and frequently swallowing difficulties that impair communication and quality of life. Injection laryngoplasty with temporary materials such as hyaluronic acid has been shown to improve voice quality and phonatory function in UVFP patients and may serve as an effective early intervention prior to permanent medialization surgery.

Objective

To assess the impact of early injection laryngoplasty on voice outcomes and voice related quality of life in patients with acute unilateral vocal fold paralysis.

Methods

This prospective study included 24 patients with acute UVFP treated with …


Epidemiologic, Clinical And Genetic Characteristics Of Familial Mediterranean Fever In Egyptian Children’S Tertiary Care Center, Ghada Ahmed Elsayed Mgahed, Mayada Sabry Zeid, Ali Sobh, Shaltout A Jan 2026

Epidemiologic, Clinical And Genetic Characteristics Of Familial Mediterranean Fever In Egyptian Children’S Tertiary Care Center, Ghada Ahmed Elsayed Mgahed, Mayada Sabry Zeid, Ali Sobh, Shaltout A

Mansoura Medical Journal

Background: Familial Mediterranean fever (FMF) is an inherited disorder known by recurrent, brief, and self-limiting episodes of fever and serosal inflammation. It is primarily defined by acute inflammatory involvement of serosal membranes, including the pleura, peritoneum, and/or synovial tissues, typically associated by fever. This inflammatory cascade is inherently self-propagating and, if inadequately controlled, may lead to recurrent episodes or sustained inflammatory activity.

Aim of the work: To examine the clinical and demographic characteristics of individuals with childhood- initiation FMF, to determine the prevalence of the most frequent mutations in the FMF-linked gene within this population, and to assess the …