Life Sciences Commons^™

Overview Of Weight Loss Medications, Malky Mandel

The Science Journal of the Lander College of Arts and Sciences

Obesity is a complex medical condition that is multifactorial in origin. About one-third of adults in the United States are obese, and another third are overweight (Ogden et al., 2007). Obesity is associated with a multitude of comorbidities, such as cardiovascular disease, diabetes mellitus, and osteoarthritis (Lim, Boster, 2023). Additionally, obesity may cause psychological disorders due to social prejudice and discrimination toward obese people (Wadden et al. 2002). Economically, obesity is also a tremendous financial burden (Tremmel et al. 2017). It is estimated that the overall cost of obesity-related illness in the US is nearly $500 billion (Cawley et al., …

What Is The Best Way To Combat The Symptoms Of Knee Osteoarthritis?, Anna Reich

The Science Journal of the Lander College of Arts and Sciences

Osteoarthritis is a debilitating disease that a significant percentage of adults contend with. This degenerative joint disease causes the breakdown of tissue at the joint, which leads to symptoms of pain, decreased function, and limited range of motion. There are various methods of combating these symptoms. Treatment options include basic lifestyle modifications and other nonpharmacological methods, oral and topical drugs, intraarticular injections, and surgery. There are benefits and risks, as well as a lack of effectiveness associated with these treatments. The purpose of this paper is to determine whether there is an optimal treatment for this disease. Based on the …

Trinity Transcript Assembly For The Titan Arum, Alveena Zulfiqar, Beenish J. Azhar, Samina N. Shakeel, William Thives Santos, Theresa D. Barry, Dana Ozimek, Kim Delong, Ruthie Angelovici, Kathleen M. Greenham, Craig A. Schenck, G. Eric Schaller

Dartmouth Scholarship

Transcriptome analysis of the titan arum was performed using floral and leaf tissues harvested from “Morphy” and “Morphy Junior,” two titan arums housed in the greenhouse of the Life Sciences Center at Dartmouth College. De novo transcript assembly for the reads obtained by RNA-seq was performed with Trinity-v2.6.6, using the default settings of >95% identity and a minimum assembled contig length of 200 nucleotides, resulting in the assembly of 915,085 transcripts that clustered as 536,644 genes.

See the following publication for details:

Zulfiqar, A., Azhar, B.J., Shakeel, S.N., Thives Santos, W., Barry, T.D., Ozimek, D., DeLong, K., Angelovici, R., Greenham, …

Physiological And Psychological Differences Between 20% Grade Incline Walking And Level-Grade Jogging At Isocaloric Intensity, Motoki Sato

Cal Poly Humboldt theses and projects

High-incline walking is a relatively new trend with little comparative information. This study compared physiological and psychological differences between high-incline walking at 20% grade (HIW) and level-grade jogging (LGJ) at isocaloric intensities in young adults. Twenty-two participants (M=11, F=11) aged 19-31 years completed the study. Participants completed HIW and LGJ on a treadmill for twenty minutes on two separate occasions and matched at isocaloric intensities. Rating of perceived exertion (RPE), maintainability (HCM), and affective valence using the Feeling Scale (FS) were measured at minutes 2, 10, and 20. Gas exchange and heart rate (HR) were continuously recorded. Post-exercise, participants completed …

Using Novel And Traditional Survey Techniques To Monitor Small Mammal Species In Northwestern California, Sydney Mccluskey

Cal Poly Humboldt theses and projects

Small mammal species play a critical role in forest ecosystems contributing significantly to overall forest biodiversity and ecological dynamics. Forest-dwelling species are among the most vulnerable to habitat loss and fragmentation. It is essential to develop efficient techniques for monitoring small mammal populations in forested ecosystems to inform conservation efforts and management plans; yet, monitoring small mammals in these habitats can be particularly challenging due to their size, activity patterns, and frequently nocturnal nature. In this study, I aimed to address two primary research objectives: 1) compare the effectiveness of 3 distinct camera-trap survey techniques (i.e., ground, tree, and tube) …

Diet, Growth, And Survival Of Juvenile Coho Salmon (Oncorhynchus Kisutch) In Off-Channel Restoration Projects In Humboldt Bay Tributaries, Katherine Rose Stonecypher

Cal Poly Humboldt theses and projects

Anthropogenic degradation of off-channel floodplain habitats has contributed to widespread declines in Pacific salmonid populations. These habitats are critical to the survival and growth of juvenile Coho Salmon during their first year of life. Restoring connectivity between mainstem and floodplain habitats could provide juvenile salmonids access to a mosaic of heterogenous foraging opportunities, with important consequences for salmonid growth and survival. I analyzed the diet, growth, and survival of juvenile Coho Salmon rearing in three restored off-channel ponds and adjacent mainstem habitats in Humboldt Bay tributaries to evaluate project performance. Juvenile Coho Salmon diet composition was significantly different among sites …

Assessing The Effects Of Remaining Northern California Kelp Forest Mesopredators On Purple Sea Urchin Abundance, Distribution, And Feeding Activity, Sandra E. Traverso

Cal Poly Humboldt theses and projects

Kelp forests are threatened by regional abiotic and biotic stressors, including overgrazing by sea urchins. On the north coast of California, purple sea urchins (Strongylocentrotus purpuratus) are prolific grazers of kelp and with the regional extinction of their main predator (sunflower stars, Pycnopodia helianthoides), it is unknown whether any remaining mesopredators could exert top-down control of purple urchin populations. Other known predators of purple urchins in northern California include rock crabs, which have been shown to control sea urchin populations in Atlantic urchin barrens and indirectly cause phase shifts back to kelp forests. Yet, little is known …

Comparative Morphology And Ultrastructure Of Olfactory Epithelia In Plethodontid Salamanders: Effect Of Life History Variation, Emily Gremling

Cal Poly Humboldt theses and projects

Many amphibian species rely on olfaction for locating prey and for social interactions during different life stages. Despite the importance of the olfactory system, research on its structure has been taxonomically limited. The most diverse family of salamanders, the Plethodontidae, has been largely excluded from research efforts to describe olfactory morphology. Although several histological studies have been conducted, no studies have yet looked at morphology at the level of ultrastructure using electron microscopy. The primary goal of my research was to examine olfactory morphology and ultrastructure in plethodontid species with a range of life history strategies, to better understand the …

Assessing Relocation Habitats And Assisted Migration Of The Lassics Lupine, An Endangered California Serpentine-Endemic, Caitlyn M. Allchin

Cal Poly Humboldt theses and projects

The Lassics lupine, Lupinus constancei, is a serpentine species endemic to the Lassics Mountains of northern California, listed as critically imperiled and federally endangered. Increased encroachment from reduced fire intervals has led to elevated herbivory from small mammals. While deployment of exclosure cages has decreased negative impacts, diminishing snowpack from shifting climate continues to threaten the Lassics lupine. To locate possible refugia, I evaluated alternative sites for assisted migration. I built a habitat suitability model (HSM) using MaxEnt software and WorldClim variables to predict optimal habitat. I then evaluated aerial imagery, topography, and geology to identify areas for microhabitat …

Using Habitat Modeling To Locate New Populations Of Dunn's Salamander (Plethodon Dunni) Near Its Southern Geographic Range Limit, Mary A. Mackey

Cal Poly Humboldt theses and projects

Habitat suitability models were utilized to direct survey efforts for Plethodon dunni in Northern California. Two models were created, one using traditional statistical methods (GLM or Generalized Linear Modeling) and the other using a machine learning method (MaxEnt or Maximum Entropy modeling). Plots were selected from areas of agreement and disagreement between the models to carry out presence surveys. The MaxEnt model yielded better predictions than the GLM model. The two models had three variables in common (annual temperature range, precipitation of driest month, and precipitation seasonality) and predicted suitable habitat within the known range of P. dunni. The …

A Case Of Incipient Budding Speciation In The California Floristic Province, Infraspecific Divergence In Abronia Villosa, Eli J. Allen

Cal Poly Humboldt theses and projects

Physical barriers to gene flow are the traditional evidence for species divergence. Conversely, there has been increasing acknowledgment of speciation in the face of gene flow as an evolutionary process. Budding speciation involves peripheral populations adapting to local ecological conditions, thereby budding off from a widespread progenitor species. Budding speciation is distinguished by ecological divergence and is generally evidenced by asymmetrical range size and nested phylogenetic relationships of sister species. The narrow endemic Abronia villosa var. aurita is adapted to montane sandy washes adjacent to its widespread sister variety, the desert dwelling var. villosa. Here, I tested the hypothesis …

The Effects Of Scour And Marginal Inundation On Trinity River Invertebrate Biomass And Density With Potential Implications For Juvenile Salmonid Food Resources, Benjamin King

Cal Poly Humboldt theses and projects

Regulated flow releases on the Trinity River in northern California have shifted the timing of high flows from winter to late spring and reduced their magnitude. The timing and extent of scour from high flow events and the timing and duration of marginal (bankside) habitat inundation has shifted as a result. Literature is sparse regarding the effects of these hydrologic alterations on Trinity River benthic macroinvertebrate (BMI) communities, an important food resource for juvenile salmonids. In the 2023 water year, a wet winter coupled with additional flow releases from Lewiston Dam provided the opportunity to analyze the impact of scour …

Assessment Of Avian Community Structure And Habitat Connectivity In The Fanno Creek Corridor Bird Surveys, Habitat Assessment, And Management Recommendations, Grace Hall

Environmental Science and Management Professional Master's Project Reports

Urbanization can significantly impact habitat quality and connectivity for avian communities, decreasing species richness and diversity. However, in highly fragmented habitats, urban parks and riparian zones can provide important habitat corridors for birds that facilitate movement and access to essential resources. On the west side of greater Portland, Oregon, Fanno Creek may serve as a habitat corridor for birds and other local wildlife.

Fanno Creek is a 25-kilometer tributary of the Tualatin River that runs through the cities of Portland, Beaverton, Tigard, and Durham in northwestern Oregon. The land surrounding the creek includes residential, commercial, and industrial properties as well …

Flowering Rush (Butomus Umbellatus) Id Guide For The Columbia River, Gabriel Campbell, Jacob Rose

Center for Lakes and Reservoirs Publications and Presentations

This is a picture based field guide for how to identify Flowering Rush (Butomus umbellatus) in the Columbia River throughout Oregon and Washington. It includes how to tell this species from commonly co-occurring look-alike species.

Aquatic Invasive Species Survey And Treatment On Lake Umatilla And Lake Celilo 2024-2025 Report, Jacob Rose, Gabriel E. Campbell

Center for Lakes and Reservoirs Publications and Presentations

Flowering Rush (Butomus umbellatus) is an invasive aquatic plant in the Pacific Northwest that threatens salmon habitat. The Center for Lakes and Reservoirs staff surveyed for this and other aquatic species from 2024 and 2025 in the Columbia River in Lake Umatilla and Lake Celilo. This document summarizes their survey efforts including their protocols, data, and small-scale removal efforts.

Effects Of Timber Harvest On Understory Vegetation Succession: A Time Series Study, Reese A. Poindexter, Trevor Weeks, Chad Bishop, Akasha Faist

Undergraduate Theses, Professional Papers, and Capstone Artifacts

Timber harvest, as a necessary and common global practice, can significantly affect the ecosystems being harvested through opening the canopy, disturbing the understory, and resetting successional trajectories. This study examined how timber harvest influenced understory plant functional group dominance, understory species richness, and understory species dominance along a 40-year, or older, harvest timeline across two forest types (mesic and xeric) in Northwestern Montana, U.S.A. In our two forest types, vegetation sampling was completed at 208 sites with 1,040 quadrats across six timber-harvest timelines. Harvest timelines varied from the most recent at 1-5 years post-harvest to over 40 years as the …

Aboveground Biomass Density Estimation Using Deep Learning: Insight From Neon Ground-Truth Data And Simulated Gedi Waveform, Ashish Mahaur

Dissertations, Master's Theses and Master's Reports

Accurately estimating Aboveground Biomass Density (AGBD) is crucial for managing Earth's carbon cycle and informing climate strategies. NASA's GEDI mission advances global forest mapping, but traditional linear models often yield less reliable AGBD estimates. This study enhances AGBD estimation using deep learning models with NEON ground-truth data and simulated GEDI waveforms. We compared 1D CNNs, LSTMs, and pre-trained CNNs to traditional models. The ResNet152 model outperformed linear regression, achieving an R² of 0.68, demonstrating a 17% improvement. Our experiments also demonstrate the importance of large, diverse datasets, particularly for training deep learning models.

Changes In Flanker Task Performance Following High-Intensity Exercise In Endurance Athletes, Felix E. Cottet-Puinel

Dissertations, Master's Theses and Master's Reports

Executive function performance following acute aerobic exercise can be influenced by multiple variables. However, little is known about the lasting effects of these exercise-induced changes. This study aimed to determine the extent to which exercise intensity impacts executive function. 14 young endurance-trained adults (5 female, 9 male) performed an Eriksen flanker task before and immediately after running high-intensity until failure and isochronal moderate-intensity (~12 min). Pre- to post-exercise-induced changes in reaction time (ms), accuracy (%), and self-reported mental effort (1-9 rating) were analyzed by overall tasks and through tasks subsections. Results showed improvement in reaction time following high- and moderate-intensity …

Trophic Interactions Of Sympatric Cyprinodontiform Fishes Inhabiting Louisiana Saltmarshes, Ryan Heines

Dissertations, Master's Theses and Master's Reports

Resident saltmarsh nekton, namely Cyprinodontiform fishes, play key ecological roles in supporting terrestrial and aquatic food webs. These fishes are highly abundant across the saltmarsh landscape of coastal Louisiana and have evolved to tolerate the highly variable environmental conditions that are characteristic of these habitats. The objective of this research is to consider mechanisms enabling this diverse community of fishes to cooccur in the spatially limited saltmarsh habitats of coastal Louisiana. In Chapter 2, bulk stable isotope ratios of carbon (δ13C), sulfur (δ34S) and nitrogen (δ15N) were used to quantify the intra- and inter-specific resource use of six sympatric Cyprinodontiform …

Automated Detection Of On-Farm Irrigation Reservoirs In Two Critical Groundwater Regions Of Arkansas: A Necessary Precursor For Conjunctive Water Management, Daniel D. Shults, John W. Nowlin, Joseph H. Massey, Michele L. Reba

Faculty Publications

In eastern Arkansas, the use of surface water for crop irrigation is steadily increasing in response to declining aquifers. Effective conjunctive water management requires accurate and timely information on the locations, sizes, and numbers of on-farm irrigation reservoirs. A method for remotely locating and characterizing on-farm reservoirs was developed using relative elevation and near-infrared imagery. With 62% accuracy, the method automatically identified 429 irrigation reservoirs within a 1.9-Mha area in less than an hour using an off-the-shelf laptop. Reservoirs not accurately identified (i.e., false negatives) were caused by the presence of vegetation or turbidity within the reservoirs. There were no …

Exploring Market Segmentation For Autonomous Ferries, Ashari Fitra Rachmannullah, Taih Cherng Lirn, Kuo Chung Shang

Journal of Marine Science and Technology–Taiwan

This study aims to investigate the determinants that underlie psychographic segmentation in the domain of autonomous ferries (AFs) by using the theory of planned behaviour (TPB) as a guiding theoretical construct. The paper focuses on Indonesian individuals who had previously utilised conventional ferry services. TPB was applied as a catalyst to identify possible market segmentation among potential AF passengers. In this study, cluster analysis is used to differentiate passengers by their perception of using AFs. The results identified three market segments through cluster analysis based on passengers’ perceptions of using AFs: Resource-Limited, Resource-Capable, and Value-Optimistic. Among these segments, the Resource-Capable …

Adaptive Prediction Horizon Energy-Saving Collision-Free Mpc Of Ships Based On Ship-Shore Cooperation, Han Xue, Enjie Yang

Journal of Marine Science and Technology–Taiwan

ABSTRACT:In order to perform the close association between ship maneuvering control and energy consumption through the control strategy, this paper designs an adaptive prediction horizon based energy-saving robust nonlinear model predictive control (APHERNMPC) for underactuated ships to deal with the actual control and state constraints during berthing based on ship-shore cooperation. An improved Emperor Penguin Optimizer (EPO) method is proposed for collision avoidance decision. To solve the problems of falling into local optimum and reducing the convergence speed, the traditional EPO is improved based on Sobol sequence in order to enhance the diversity and ergodicity of the population. The multi-ship …

Research And Design A Lifeboat Virtual Reality Simulation System For Maritime Safety Training In Vietnam, Nguyen Dinh Thach, Nguyen Van Hung

Journal of Marine Science and Technology–Taiwan

Ensuring maritime safety and security is crucial for all nations. Training trainees and operational officers in this field aims to enhance their professional skills and ability to manage and resolve incidents at sea. This article outlines the development of a lifeboat simulation system that integrates Virtual Reality (VR) technology in accordance with international maritime regulations. It describes the creation of an algorithm designed to optimize data transmission between simulation systems using the ant colony optimization technique in conjunction with intelligent control algorithms on Unity 3D software for human interaction. In particular, the system combines training with a maritime simulation framework …

Understanding Angler Responses To Fish Stocking Programs Across South Dakota, Riley L. Mounsdon

Electronic Theses and Dissertations

Fisheries management is a complex process that often requires consideration of many factors to be implemented effectively. Stocking is one of the most often used fisheries management techniques for addressing a myriad of issues in the fisheries field. Stocking is also one of the largest expenses for many fisheries management agencies. Due to license sale declines, management actions including stocking, are being evaluated by many agencies to determine if there are ways to improve efficiency and effectiveness to reduce costs and enhance angler participation. For my second chapter, I evaluated the current fish stocking decision-making process within South Dakota Game, …

Nutrient Intake, Performance, And Body Composition In Preseason Wrestlers, Gregory Coapstick

Electronic Theses and Dissertations

BACKGROUND: College athletes, especially in weight class sports, often experience energy deficits. Weight class sports such as wrestling are at greatest risk for deficiencies, and little is known about the relationships between body composition, nutrient intake, and performance in these athletes.
OBJECTIVES: The purposes of this study were to quantify macronutrient and micronutrient intake of pre-season male collegiate wrestlers and compare to recommendations, and examine relationships among nutritional intakes, body composition, and performance measurements of strength, anaerobic, and aerobic capacity.
METHODS: Male Division I wrestlers (n=11, mean ± SD age: 21.3±1.7 years, wrestling experience: 14.9±2.5 years) were recruited during preseason. …

Influence Of Reduced Salt In Fully Cooked Ham And Sausage Cured With Natural Celery Powder On The Growth Of Listeria Monocytogenes At 4⁰C, Anne Sherod

Electronic Theses and Dissertations

This research evaluated the influence of reducing salt on outgrowth of L. monocytogenes on ready to eat (RTE) deli-style sliced ham cured with natural celery powder, fully cooked sausage links cured with traditional sodium nitrite and sausage links cured with natural celery powder, vacuum packaged and stored at 4⁰C on the outgrowth of L. monocytogenes. Experiment 1 evaluated L. monocytogenes outgrowth on ham over 153 days on the following treatments, current retail ham (HC) 2.0% salt; reduced salt 1 (HRS1) 1.5% salt; reduced salt 2 (HSR2) 1.35% salt; and reduced salt 2 without antimicrobials (HRS2WA) 1.35% salt without potassium lactate …

Various Surfactant Soil Conditioner Effect On Plant Nutrient Concentration, Soil Nutrient Depletion, Soil Volumetric Water Content, Plant Biomass And Yield In Corn, Timothy Veldkamp

Electronic Theses and Dissertations

Soil conditioners help improve soil structure by increasing aeration, water infiltration and water holding capacity leading to nutrient availability and reduced irrigation needs. The goal of this study was to evaluate the impact of multiple soil conditioners (SC1, SC2, SC3, SC4, and SC5) on corn (Zea mays L.) and their ability to reduce irrigation by 30%. This was evaluated in the field in 2022 and 2023 by Aurora, SD using a Randomized Complete Block Design with six replications. Conditioners were applied as broadcast pre-emergence treatments with 70% irrigation. Control treatments of 70% and 100% irrigation, respectively were included. SC1 application …

Role Of Production Systems On Carcass And Palatability Attributes Of Bison, Lydia Margaret Hite O'Sullivan

Electronic Theses and Dissertations

The overall objective of this dissertation was to determine the impact of finishing systems on carcass and palatability attributes of bison. The specific objectives were 1) determine the influence of finishing system (grain-finished vs. grass-finished) on the mechanisms of tenderness formation in the longissimus lumborum of bison bulls, 2) determine the influence of diverse finishing systems on carcass characteristics and proximate composition of bison heifers, and 3) determine the influence of diverse finishing systems on palatability of striploin steaks from bison heifers. Results indicate that finishing systems differentially influence carcass characteristics, tenderness, and flavor attributes of bison. Specifically, this is …

Genetic And Ecologic Effects Of Seed Dormancy Genes On Seed Aging, Soil Seedbank Longevity, And Microbiome In An Isogenic Background Of Rice ( Oryza Sativa L.), Bhupinder Singh Batth

Electronic Theses and Dissertations

No abstract provided.

Whole Genome Crispr-Cas9 Screens Identify Genes Contributing To Viral Entry And Phagocytosis, Md Saddam Hossain

Electronic Theses and Dissertations

CRISPR/Cas9 is a revolutionary technique for genome editing where Cas9 nucleases can be targeted to specific genomic sites by single-guide RNAs (sgRNAs) containing roughly 20-nucleotide sequences that are complementary to the target region. Double strand breaks created by Cas9 are repaired through non-homologous end-joining (NHEJ) in most cells, resulting in insertions and deletions leading to frame shift mutations in coding regions. Thus, the CRISPR-Cas9 system can be exploited for systematic evaluation of gene function relationships by whole genome screening. We also developed a CRISPR whole‐genome screen and counter‐screen strategy based on a pseudoviral platform that allowed identification of genes specific …