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Articles 27151 - 27180 of 255951
Full-Text Articles in Life Sciences
Extraction Of Natural Dyes From Delonix Regia Flowers For Cotton Fibres, Lutamyo Nambela, Liberato V Haule
Extraction Of Natural Dyes From Delonix Regia Flowers For Cotton Fibres, Lutamyo Nambela, Liberato V Haule
Tanzania Journal of Science
Textile colouration is among the major industry that pollutes the environment with effluents rich in dye chemicals. Most of the dyes used are synthetics which possess health and environmental impacts. Potentially, the use of bio-based dyes and other chemicals can lessen the environmental challenges of the textile effluents. This study reports on sustainable extraction and dyeing of cotton fabric using extract of Delonix regia flowers. The extraction process was done using acidified water as a solvent and the dyeing process was free from hazardous auxiliary chemicals. To improve the dyeing performance, banana sap was used as an affordable and eco-friendly …
Modeling The Transmission Dynamics Of Tuberculosis In Humans, Farida Kisinda, Joshua A. Mwasunda, Mbwiga S. Aloni
Modeling The Transmission Dynamics Of Tuberculosis In Humans, Farida Kisinda, Joshua A. Mwasunda, Mbwiga S. Aloni
Tanzania Journal of Science
Tuberculosis (TB) is a major threat to human health particularly in most of developing countries. In this article, we formulate and analyze a deterministic model for the transmission dynamics of pulmonary and extra-pulmonary tuberculosis. The next generation method is employed to find the basic reproduction number which helps to determine whether TB clears or persists in the human population. Global stability of model equilibria is done through Lyapunov functions whereas the normalized forward sensitivity index method is adopted to determine parameters that drive tuberculosis. Analysis shows that both TB free and endemic equilibria exist. The TB free equilibrium is globally …
Genetic Characterization Of Water Yam (Dioscorea Alata L.) And Production Constraints Of Yam In Pwani Region And Unguja Island, Tanzania, Gladness E Temu, Veneranda E Mlegi, Nessie D Luambano
Genetic Characterization Of Water Yam (Dioscorea Alata L.) And Production Constraints Of Yam In Pwani Region And Unguja Island, Tanzania, Gladness E Temu, Veneranda E Mlegi, Nessie D Luambano
Tanzania Journal of Science
Yam (Dioscorea spp.) is a tuber crop cultivated in over 30% of all regions in Tanzania, contributing to the carbohydrate needs of many households. The morphological and genetic diversity of water yam (D. alata L.) local cultivars collected from Pwani region and Unguja Island were evaluated using 26 agro-morphological characters and 10 Short Sequence Repeat (SSR) markers. Cluster analysis using morphological characters classified nine water yam local cultivars into two main clusters with three subclusters. Tuber flesh and leaf colour were the main descriptors for clustering. The genetic diversity of 128 water yam genotypes using ten polymorphic SSR markers generated …
Microbiological Quality Of Irrigation Water And Leafy Vegetables In Dar Es Salaam, Tanzania, Bubelwa L. Kamara, Godwill D. Mrema, Thomas J. Lyimo
Microbiological Quality Of Irrigation Water And Leafy Vegetables In Dar Es Salaam, Tanzania, Bubelwa L. Kamara, Godwill D. Mrema, Thomas J. Lyimo
Tanzania Journal of Science
The quality of water used for the irrigation of leafy vegetables in urban settings is in doubt due to contamination associated with poor hygiene and water pollution. This study examined the microbiological quality of irrigation water and leafy vegetables at Chang’ombe in Dar es Salaam, Tanzania as well as the perceptions and level of awareness of nearby consumers. Water and leafy vegetable samples were analysed for faecal coliform (FC) using standard techniques. Perception and awareness of consumers were collected using a questionnaire survey. The results showed an average FC count of 406.1 ± 16.40 MPN/100 ml for the irrigation water. …
Modelling The Combined Use Of Long-Lasting Insecticidal Nets And Insecticides Zooprophylaxis Against The Resilience Of Anopheles Arabiensis For Effective Malaria Control, Watson Levens
Tanzania Journal of Science
Malaria is a significant public health concern, especially in tropical regions. It remains endemic in many areas where malaria mosquitoes are prevalent. This study investigates the viability of insecticide zooprophylaxis (IZ) in conjunction with Long Lasting Insecticidal Nets (LLINs) as a strategic approach to combat malaria transmission, particularly in regions dominated by zoophagic vectors. Through the presentation and analysis of a mathematical model that integrates IZ and LLINs for the control of Anopheles arabiensis (An. arabiensis), the research underscores IZ's role in reducing zoophagic vector populations and enhancing malaria control efforts. Notably, the study reveals that achieving comprehensive coverage of …
Green And Blue Water Footprints Of Major Crops In The Wami/Ruvu Basin, Tanzania: Implications For Water Scarcity And Sustainability, Benson Hm Lazaro, Martine M. Hagai, Rubhera Ram Mato
Green And Blue Water Footprints Of Major Crops In The Wami/Ruvu Basin, Tanzania: Implications For Water Scarcity And Sustainability, Benson Hm Lazaro, Martine M. Hagai, Rubhera Ram Mato
Tanzania Journal of Science
Accurate estimation of the blue and green water requirements of the various crops cultivated in a water basin is essential for planning specific plant/crop irrigation schedules. In this study, the crop water requirements of the major crops grown in the Wami/Ruvu basin were determined using the FAO-CROPWAT model based on meteorological parameters: monthly maximum and minimum temperature, wind speed, mean relative humidity, sunshine hours, rainfall data, and effective rainfall for 23 hydro-meteorological stations distributed in the study area. The studied crops are rice, maize, beans, tomatoes, and sugarcane. The crop reference evapotranspiration (ETo) and actual evapotranspiration (ETc) for each crop …
Modelling And Mapping Of Forest Biodiversity Indicators Using Sentinel-2 And Planetscope Remotely Sensed Data, Diana L. Tesha, Ernest W. Mauya, Sami D. Madundo
Modelling And Mapping Of Forest Biodiversity Indicators Using Sentinel-2 And Planetscope Remotely Sensed Data, Diana L. Tesha, Ernest W. Mauya, Sami D. Madundo
Tanzania Journal of Science
Tropical montane forests harbour exceptionally high biodiversity yet face severe threats from human activities. Assessing forest biodiversity over large areas is crucial yet extremely challenging. Remote sensing provides an efficient monitoring solution, but few studies have focused on Tanzania's diverse, montane forests. We collected field data on tree species composition within 159 plots across montane forests in Tanzania's West Usambara region. We calculated species richness, evenness, and Shannon diversity index as indicators of tree diversity. Using Sentinel-2 and PlanetScope satellite imagery, we derived spectral, textural, and vegetation index predictors to model these indices via generalized additive models and extreme gradient …
Relationship Of Stress And Other Factors With Emotional Eating Among Adolescents In Depok, Muthia Syifa Rahmadina, Asih Setiarini
Relationship Of Stress And Other Factors With Emotional Eating Among Adolescents In Depok, Muthia Syifa Rahmadina, Asih Setiarini
Indonesian Journal of Public Health Nutrition (IJPHN)
Emotional eating is an overeating behavior as a coping mechanism for negative emotions that emerges in adolescence. Emotional eating causes obesity, eating disorders, and non-communicable diseases. This study aims to determine the relationship between stress, body image, peer influence, parental rearing styles, social media use, sex, sleep quality, and emotion regulation with emotional eating among adolescents at senior high school in Depok. This cross-sectional quantitative study was conducted online in March 2022. The samples were grade X and XI students from senior high school in Depok who were chosen by using purposive sampling techniques (n=174). Chi X2 test and Mann …
Determinant Factors Of The Incidence Of Low Birth Weight In Central Java Province: Analysis Of 2018 Basic Health Research Data, Desi Irawati, Ratu Ayu Dewi Sartika, Diah Mulyawati Utari, Fadila Wirawan
Determinant Factors Of The Incidence Of Low Birth Weight In Central Java Province: Analysis Of 2018 Basic Health Research Data, Desi Irawati, Ratu Ayu Dewi Sartika, Diah Mulyawati Utari, Fadila Wirawan
Indonesian Journal of Public Health Nutrition (IJPHN)
Low birth weight (LBW) is a global public health issue with significant short and long-term consequences for individuals and societies. This study aims to examine the most dominant risk and variations in the proportion of LBW based on fetal factors, maternal and obstetric factors, and sociodemographic factors among toddlers in Central Java Province, utilizing the 2018 Basic Health Research (RISKESDAS) data. The study used a cross-sectional study conducted on 4255 samples, utilizing univariate, bivariate (chi-square), and multivariate analysis (multiple logistic regression). Central Java has the 3rd highest number of LBW cases in Indonesia with a prevalence of 6.1%. However, univariate …
Sugar-Sweetened Beverages Consumption Based On Individual And Environmental Factors Among The Faculty Of Public Health Universitas Indonesia’S Students In 2023, Safira Diva Aranis, Wahyu Kurnia Yusrin Putra, Asih Setiarini, Teguh Jati Prasetyo
Sugar-Sweetened Beverages Consumption Based On Individual And Environmental Factors Among The Faculty Of Public Health Universitas Indonesia’S Students In 2023, Safira Diva Aranis, Wahyu Kurnia Yusrin Putra, Asih Setiarini, Teguh Jati Prasetyo
Indonesian Journal of Public Health Nutrition (IJPHN)
Sugar-sweetened beverages (SSB) are beverages that contain added sugars. Excessive consumption of SSB can have an impact on health. Some of the effects caused by SSB include obesity, fatty liver, type II diabetes, hypertension, heart disease, nutritional deficiencies, and dental caries. This research aims to determine the differences in the proportion of SSB consumption based on individual and environmental factors among students of the Faculty of Public Health UI (FPH UI) in 2023. This study uses a cross sectional design with a sample size of 194 individuals. The researcher collected data including respondent’s identities, habits of reading food labels, knowledge …
The Differences In Maternal Clean And Healthy Living Behavior In The Incidence Of Stunting In Yogyakarta, Shafa Ramadhita, Anindhita Syahbi Syagata, Nor Eka Noviani
The Differences In Maternal Clean And Healthy Living Behavior In The Incidence Of Stunting In Yogyakarta, Shafa Ramadhita, Anindhita Syahbi Syagata, Nor Eka Noviani
Indonesian Journal of Public Health Nutrition (IJPHN)
An indirect cause of stunting is maternal behavior. Moreover, good nutritional knowledge relates to good nutritional behaviors. Maternal clean and Healthy Living Behavior (PHBS) in daily life can reduce the risk of infectious diseases and be role models for children in implementing their future health behavior. The study aims to investigate the differences in PHBS of mothers in the incidence of stunting ages 24-59 months in the Minggir Primary Health Center working area. The cross-sectional approach of this research was conducted from March to April 2023. The subjects of this study were 69 respondents selected by cluster random sampling. The …
Factors Associated With Wasting In Toddlers Aged 6 – 59 Months At Cimpaeun Village, Depok City, West Java, Indonesia In 2023, Early Vici Azmia, Triyanti Triyanti
Factors Associated With Wasting In Toddlers Aged 6 – 59 Months At Cimpaeun Village, Depok City, West Java, Indonesia In 2023, Early Vici Azmia, Triyanti Triyanti
Indonesian Journal of Public Health Nutrition (IJPHN)
The prevalence of wasting under five in Indonesia in 2022 is 7.7%; according to WHO, this wasting problem is a serious public health problem. Wasting is a nutritional problem in toddlers that has an impact on morbidity and mortality. The research objective was to determine the factors associated with wasting in toddlers aged 6–59 months in Cimpaeun Village in 2023. The dependent variable is wasting, and the independent variables are birth weight, history of fever, diarrhea, acute respiratory infection, energy intake, carbohydrate intake, protein intake, fat intake, mother’s age, pregnancy, mother’s education level, mother’s nutritional knowledge, and family income. This …
The Relationship Of Energy And Nutrient Intake From Eating Out And Eating At Home On Blood Hemoglobin Levels In Adolescents, Adinda Aisyah Putri, Khoirul Anwar
The Relationship Of Energy And Nutrient Intake From Eating Out And Eating At Home On Blood Hemoglobin Levels In Adolescents, Adinda Aisyah Putri, Khoirul Anwar
Indonesian Journal of Public Health Nutrition (IJPHN)
Eating out of home is a common practice in adolescents. The high frequency of eating out of home characterized by higher intakes of energy, fats, sugar, and sodium. anemia, especially iron deficiency anemia which is characterized by blood hemoglobin levels, is still a nutritional problem in Indonesia in adolescents which can have an impact on adolescent health. The aim of this study was to determine the relationship between eating out and hemoglobin levels in adolescents in Jakarta. This research is an observational study with a cross sectional research design. The subjects of this research were female students aged 15-17 years. …
Smokejumper Obituary: Jackson, Harley Sterling (Redmond 1986), National Smokejumper Association
Smokejumper Obituary: Jackson, Harley Sterling (Redmond 1986), National Smokejumper Association
Smokejumper Obituaries
No abstract provided.
Effects Of Silymarin On S. Aureus Atcc25923 Biofilm And Its Virulence Factors, Wang Jiakang, Tang Haoguo, Chen Jing, Si Qihe, Shen Ruxiao
Effects Of Silymarin On S. Aureus Atcc25923 Biofilm And Its Virulence Factors, Wang Jiakang, Tang Haoguo, Chen Jing, Si Qihe, Shen Ruxiao
Food and Machinery
Objective: In this study, the effects of silymarin on the biofilm S. aureus ATCC25923 and its virulence factors were investigated. Methods: The inhibition and clearance of silymarin on S. aureus ATCC25923 biofilm formation were detected by crystal violet staining, the effects of silymarin on its biofilm metabolism were investigated by MTT staining, and the effects of silymarin on its coagulase expression and hemolytic activity were investigated by freeze-dried plasma and aseptic defibrinated sheep blood. In parallel, the effects of different concentrations of silymarin on its biofilm and Fourier transform were observed under an optical microscope. Results: The results showed that …
Papaya Maturity Detection Based On Multi-Target Sampling And Improved Mask R-Cnn, Qi Guohong, Zhang Yunlong, Su Man
Papaya Maturity Detection Based On Multi-Target Sampling And Improved Mask R-Cnn, Qi Guohong, Zhang Yunlong, Su Man
Food and Machinery
Objective: Improve the accuracy and robustness of papaya ripeness detection. Methods: A method of papaya ripeness detection based on multi-target sampling and improved Mask R-CNN was proposed. In the process of data expansion, the method introduced multi-object sampling technology to generate enhanced images from small data sets taken under controlled conditions, which was conducive to extending the proposed method to data sets with complex features of actual papaya images. The effectiveness and robustness of the proposed method were verified by means of average accuracy, accuracy, accuracy-recall curve and calculation time, and the results of papaya ripeness detection effect were compared …
Uncertainty Evaluation For The Determination Of Four Quinolone Residues In Honey By Liquid Chromatography-Tandem Mass Spectrometry, Yang Yun, Cao Yang, Li Jing, Zhong Feifei, Zuo He
Uncertainty Evaluation For The Determination Of Four Quinolone Residues In Honey By Liquid Chromatography-Tandem Mass Spectrometry, Yang Yun, Cao Yang, Li Jing, Zhong Feifei, Zuo He
Food and Machinery
Objective: This study aimed to evaluate the determination uncertainty of four quinolones residues in honey by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Methods: Based on GB 31657.2—2021, a mathematical model for sources of uncertainty evaluation was established. The uncertainty of each variable which affect the result were calculated and the weight of each uncertainty component was assessed. Results: The uncertainties in the determination of enrofloxacin, sarafloxacin, ofloxacin and ciprofloxacin in honey were (4.97±0.81), (10.13±1.58), (7.67±1.23), (14.97±2.25) μg/kg (P=95%,k=2) respectively. Conclusion: The main influencing factors of the determination uncertainty were preparation and dilution process of standard solution and …
Effects Of Four Packaging Materials On Preservation Of Passion Flower (Passiflora Caerulea L.) Fruit, Lin Yuzhao, Chen Leiyi, Chen Hongbin, Zheng Jinshui, Jiang Xuanjing, Yang Jingmei
Effects Of Four Packaging Materials On Preservation Of Passion Flower (Passiflora Caerulea L.) Fruit, Lin Yuzhao, Chen Leiyi, Chen Hongbin, Zheng Jinshui, Jiang Xuanjing, Yang Jingmei
Food and Machinery
Objective: The preservation effects of four packaging materials on passion fruit were studied. Methods: The fruit of passion flower cv. Huangjin (maturity: eight) was used as the research material, and passion flower fruit was treated via polyvinyl chloride (PVC) film, polyethylene (PE) bag, bidirectional stretch polyolefin (BSP) heat shrinkable film, biodegradable modified atmosphere (BMA) bag, respectively, with untreated ones as the control group. Then, the fruits was stored at temperature of (25±1) ℃ and relative humidity of 85% for fifteen days, and the preservation indices of fruit were measured every three days. Results: Compared to control passion fruit, the four …
Structural Characteristics And Hypoglycemic Activity Of Polysaccharides From Different Parts Of Wampee, He Junye, Liu Cheng, Yu Chongyang, Sun Pengpeng, Ren Yuanyuan
Structural Characteristics And Hypoglycemic Activity Of Polysaccharides From Different Parts Of Wampee, He Junye, Liu Cheng, Yu Chongyang, Sun Pengpeng, Ren Yuanyuan
Food and Machinery
Objective: This study aimed to develop antioxidant products and anti-diabetes drugs of wampee. The study aimed to research the structural characteristics, anti-oxidation and hypoglycemic properties in vitro of polysaccharides from different parts of wampee. Methods: The structural properties, in vitro antioxidant and hypoglycemic activities of polysaccharides from the fruit, peel and seeds of wampee (CWP-F, CWP-P, and CWP-S) were analyzed and compared from the aspects of chemical composition, molecular weight, monosaccharide composition, appearance, DPPH free radical scavenging rate and α-amylase inhibition rate. Results: CWP-F had the highest molecular weight and was mainly composed of galactose and arabinose, CWP-P was mainly …
Extraction Of Active Ingredients From Penthorum Chinense Pursh And Comparison Of Component Distribution In Different Parts, Xiang Zhuoya, Zhu Boyu, Zhu Yongqing, Xia Chen, Chen Song
Extraction Of Active Ingredients From Penthorum Chinense Pursh And Comparison Of Component Distribution In Different Parts, Xiang Zhuoya, Zhu Boyu, Zhu Yongqing, Xia Chen, Chen Song
Food and Machinery
Objective: This study aimed to determine the extraction solvent and compare the distribution of functional ingredient and antioxidant activities in different parts of Penthorum chinense pursh. Methods: the total phenolic content, total flavonoid content, antioxidant capacity and individual phenolic compounds content in Penthorum chinense pursh were determined and analyzed. Results: The total phenolic content, total flavonoid content increased and then decreased with the increase of solvent concentration. The seven main phenolic compounds (catechin, rutin, pinocembrin-7-O-glucoside, quercetin, kaempferol, pinocembrin and thonningianin A), ABTS radical scavenging ability, and ferric ion reduction ability were the highest in 80% ethanol extract. The …
Comparative Study On Several Black Bean Components, Antioxidant And Enzyme Inhibition In Vitro, Dang Yuting, Zhang Yan, Jing Boxing, Su Xiaomeng, Chai Xiyan
Comparative Study On Several Black Bean Components, Antioxidant And Enzyme Inhibition In Vitro, Dang Yuting, Zhang Yan, Jing Boxing, Su Xiaomeng, Chai Xiyan
Food and Machinery
Objective: The difference in bioactive substance content and bioactivity in black beans were compared. Methods: The contents of total phenolic acids, total flavonoids, condensed tannins, total anthocyanins, total polysaccharides and total proteins of nine kinds of black beans were determined. The antioxidant activities of black bean extracts in vitro and their inhibitory effects on α-amylase, pancreatic lipase, acetylcholinesterase and tyrosinase were compared. Results: The contents of total phenolic acid, total flavonoids, condensed tannins and total anthocyanins were as follows: equine bean > small black bean > black bean; Total polysaccharide content: small black bean > black bean > horse bean; Total protein content: horse …
What Is Trauma?: From Science To Social Justice, Judith Fleetwood Carlisle
What Is Trauma?: From Science To Social Justice, Judith Fleetwood Carlisle
Arts & Sciences Graduate Student Theses and Dissertations
In recent years, the term “trauma” has become increasingly controversial. Many of these controversies revolve around the definition of trauma, and the way that this definition varies across contexts. What kinds of experience can plausibly be considered “traumatic”? In some contexts, the standards are incredibly permissive, while others are much more restrictive. These different ways of understanding “trauma” prompts an important question: Who has the authority to define trauma? In other words, who decides which conception of trauma is the most “legitimate” – who decides when an experience is or is not traumatic? My project attempts to answer these questions …
Dimerization Of The Fluoride Channel Fluc In Membranes, Melanie Ernst
Dimerization Of The Fluoride Channel Fluc In Membranes, Melanie Ernst
Arts & Sciences Graduate Student Theses and Dissertations
Many ion channels are multi-subunit complexes where oligomerization is an obligatory requirement for function as the binding axis forms the charged permeation pathway. However, the mechanisms of assembly within the membrane are largely unknown. Are ion channel complexes thermodynamically stable, and do they participate in dynamic equilibrium oligomerization reactions in membranes? If so, what are the molecular factors governing these reactions? In this thesis, I present several key advances in the study of ion channel oligomerization in membranes through quantitative studies of the dimerization equilibrium reaction of the inverted topology, homodimeric fluoride channel Fluc in lipid bilayers. Chapter 1 provides …
Design A Friendly Nanoscale Chemical Sensor Based On Gold Nanoclusters For Detecting Thiocyanate Ions In Food Industry Applications, Reham Ali, Sayed M Saleh
Design A Friendly Nanoscale Chemical Sensor Based On Gold Nanoclusters For Detecting Thiocyanate Ions In Food Industry Applications, Reham Ali, Sayed M Saleh
Faculty, Staff and Student Publications
The surfactant cetyltrimethylammonium bromide (CTAB) induces the aggregation of gold nanoclusters (GNCs), leading to the development of a proposed fluorometric technique for detecting thiocyanate (SCN-) ions based on an anti-aggregation mechanism. This approach is straightforward to execute, highly sensitive, and selective. A significant quenching effect occurs in fluorescence upon using the aggregation agent CTAB in GNCs synthesis, resulting in a transition from intense red fluorescence to dim red. The decrease in fluorescence intensity of GNCs in the presence of CTAB is caused by the mechanism of fluorescence quenching mediated by aggregation. As the levels of SCN- rise, the fluorescence of …
Financial Hardship And Neighborhood Socioeconomic Disadvantage In Long-Term Childhood Cancer Survivors, Alex J Fauer, Weiyu Qiu, I-Chan Huang, Patricia A Ganz, Jacqueline N Casillas, Gregory T Armstrong, Rebecca Howell, Carrie R Howell, Anne C Kirchhoff, Yutaka Yasui, Paul C Nathan
Financial Hardship And Neighborhood Socioeconomic Disadvantage In Long-Term Childhood Cancer Survivors, Alex J Fauer, Weiyu Qiu, I-Chan Huang, Patricia A Ganz, Jacqueline N Casillas, Gregory T Armstrong, Rebecca Howell, Carrie R Howell, Anne C Kirchhoff, Yutaka Yasui, Paul C Nathan
Faculty, Staff and Student Publications
Background: Long-term survivors of childhood cancer face elevated risk for financial hardship. We evaluate whether childhood cancer survivors live in areas of greater deprivation and the association with self-reported financial hardships.
Methods: We performed a cross-sectional analysis of data from the Childhood Cancer Survivor Study between 1970 and 1999 and self-reported financial information from 2017 to 2019. We measured neighborhood deprivation with the Area Deprivation Index (ADI) based on current zip code. Financial hardship was measured with validated surveys that captured behavioral, material and financial sacrifice, and psychological hardship. Bivariate analyses described neighborhood differences between survivors and siblings. Generalized linear …
Quorum-Sensing Agr System Of Staphylococcus Aureus Primes Gene Expression For Protection From Lethal Oxidative Stress, Magdalena Podkowik, Andrew I Perault, Gregory Putzel, Andrew Pountain, Jisun Kim, Erin E Zwack, Theodora K Karagounis, Chunyi Zhou, Andreas F Haag, Julia Shenderovich, Gregory A Wasserman, Junbeom Kwon, John Chen, Anthony R Richardson, Jeffrey N Weiser, Carla R Nowosad, Desmond S Lun, Dane Parker, Alejandro Pironti, Xilin Zhao, Karl Drlica, Itai Yanai, Victor J Torres, Bo Shopsin
Quorum-Sensing Agr System Of Staphylococcus Aureus Primes Gene Expression For Protection From Lethal Oxidative Stress, Magdalena Podkowik, Andrew I Perault, Gregory Putzel, Andrew Pountain, Jisun Kim, Erin E Zwack, Theodora K Karagounis, Chunyi Zhou, Andreas F Haag, Julia Shenderovich, Gregory A Wasserman, Junbeom Kwon, John Chen, Anthony R Richardson, Jeffrey N Weiser, Carla R Nowosad, Desmond S Lun, Dane Parker, Alejandro Pironti, Xilin Zhao, Karl Drlica, Itai Yanai, Victor J Torres, Bo Shopsin
Faculty, Staff and Student Publications
The agr quorum-sensing system links Staphylococcus aureus metabolism to virulence, in part by increasing bacterial survival during exposure to lethal concentrations of H2O2, a crucial host defense against S. aureus. We now report that protection by agr surprisingly extends beyond post-exponential growth to the exit from stationary phase when the agr system is no longer turned on. Thus, agr can be considered a constitutive protective factor. Deletion of agr resulted in decreased ATP levels and growth, despite increased rates of respiration or fermentation at appropriate oxygen tensions, suggesting that Δagr cells undergo a shift towards a hyperactive metabolic …
Phase I Trial Of Single-Photon Emission Computed Tomography-Guided Liver-Directed Radiotherapy For Patients With Low Functional Liver Volume, Enoch Chang, Franklin C L Wong, Beth A Chasen, William D Erwin, Prajnan Das, Albert C Koong, Bruce D Minsky, Sonal S Noticewala, Grace L Smith, Cullen M Taniguchi, Maria J Rodriguez, Sam Beddar, Rachael M Martin-Paulpeter, Joshua S Niedzielski, Gabriel O Sawakuchi, Emil Schueler, Luis A Perles, Lianchun Xiao, Janio Szklaruk, Peter C Park, Arvind N Dasari, Ahmed O Kaseb, Bryan K Kee, Sunyoung S Lee, Michael J Overman, Jason A Willis, Robert A Wolff, Ching-Wei D Tzeng, Jean-Nicolas Vauthey, Eugene J Koay
Phase I Trial Of Single-Photon Emission Computed Tomography-Guided Liver-Directed Radiotherapy For Patients With Low Functional Liver Volume, Enoch Chang, Franklin C L Wong, Beth A Chasen, William D Erwin, Prajnan Das, Albert C Koong, Bruce D Minsky, Sonal S Noticewala, Grace L Smith, Cullen M Taniguchi, Maria J Rodriguez, Sam Beddar, Rachael M Martin-Paulpeter, Joshua S Niedzielski, Gabriel O Sawakuchi, Emil Schueler, Luis A Perles, Lianchun Xiao, Janio Szklaruk, Peter C Park, Arvind N Dasari, Ahmed O Kaseb, Bryan K Kee, Sunyoung S Lee, Michael J Overman, Jason A Willis, Robert A Wolff, Ching-Wei D Tzeng, Jean-Nicolas Vauthey, Eugene J Koay
Faculty, Staff and Student Publications
BACKGROUND: Traditional constraints specify that 700 cc of liver should be spared a hepatotoxic dose when delivering liver-directed radiotherapy to reduce the risk of inducing liver failure. We investigated the role of single-photon emission computed tomography (SPECT) to identify and preferentially avoid functional liver during liver-directed radiation treatment planning in patients with preserved liver function but limited functional liver volume after receiving prior hepatotoxic chemotherapy or surgical resection.
METHODS: This phase I trial with a 3 + 3 design evaluated the safety of liver-directed radiotherapy using escalating functional liver radiation dose constraints in patients with liver metastases. Dose-limiting toxicities were …
Pathological Response In Resectable Non-Small Cell Lung Cancer: A Systematic Literature Review And Meta-Analysis, Nathalie A Waser, Melanie Quintana, Bernd Schweikert, Jamie E Chaft, Lindsay Berry, Lien Vo, Joseph Fiore, Donald A Berry, Sarah Goring
Pathological Response In Resectable Non-Small Cell Lung Cancer: A Systematic Literature Review And Meta-Analysis, Nathalie A Waser, Melanie Quintana, Bernd Schweikert, Jamie E Chaft, Lindsay Berry, Lien Vo, Joseph Fiore, Donald A Berry, Sarah Goring
Faculty, Staff and Student Publications
BACKGROUND: Surrogate endpoints for overall survival in patients with resectable non-small cell lung cancer receiving neoadjuvant therapy are needed to provide earlier treatment outcome indicators and accelerate drug approval. This study's main objectives were to investigate the association among pathological complete response, major pathological response, event-free survival and overall survival and to determine whether treatment effects on pathological complete response and event-free survival correlate with treatment effects on overall survival.
METHODS: A comprehensive systematic literature review was conducted to identify neoadjuvant studies in resectable non-small cell lung cancer. Analysis at the patient level using frequentist and Bayesian random effects (hazard …
Study On A Strong Polymer Gel By The Addition Of Micron Graphite Oxide Powder And Its Plugging Of Fracture, Zhonghui Li, Fangping Chen
Study On A Strong Polymer Gel By The Addition Of Micron Graphite Oxide Powder And Its Plugging Of Fracture, Zhonghui Li, Fangping Chen
Faculty, Staff and Student Publications
It is difficult to plug the fracture water channeling of a fractured low-permeability reservoir during water flooding by using the conventional acrylamide polymer gel due to its weak mechanical properties. For this problem, micron graphite powder is added to enhance the comprehensive properties of the acrylamide polymer gel, which can improve the plugging effect of fracture water channeling. The chemical principle of this process is that the hydroxyl and carboxyl groups of the layered micron graphite powder can undergo physicochemical interactions with the amide groups of the polyacrylamide molecule chain. As a rigid structure, the graphite powder can support the …
Supporting Text And Data Analysis Across Campus From The Academic Library, Amy Kirchhoff, Hejin Shin Phd
Supporting Text And Data Analysis Across Campus From The Academic Library, Amy Kirchhoff, Hejin Shin Phd
Digital Initiatives Symposium
The ability to comprehend and communicate with text-based data is essential to future success in academics and employment, as evidenced in a recent survey from Bloomberg Research Services which shows that nearly 97% of survey respondents now use data analytics in their companies and 58% consider data and text mining a business analytics tool (https://www.sas.com/content/dam/SAS/bp_de/doc/studie/ba-st-the-current-state-of-business-analytics-2317022.pdf). This has fueled a substantial growth in text analysis research (involving the use of technology to analyze un- and semi-structured text data for valuable insights, trends, and patterns) across disciplines and a corresponding demand on academic libraries to support text analysis pedagogy and text analysis …