Life Sciences Commons^™

Interactions Between Repetitive Mild Traumatic Brain Injury And Methylphenidate Administration On Catecholamine Transporter Protein Levels Within The Rodent Prefrontal Cortex, Anna Abrimian, Eleni Papadopoulos, Christopher P. Knapp, J. Loweth, Barry Waterhouse, Rachel Navarra

Rowan-Virtua Research Day

It is theorized that low concentrations of dopamine (DA) and norepinephrine (NE) within in the prefrontal cortex (PFC) following traumatic brain injury (TBI) leads to increased risky behavior. Our lab has shown that repeated mild TBI (rmTBI) sex-differentially increases risky behavior in a rodent model. Methylphenidate (MPH) is a psychostimulant drug used to treat symptoms of Attention-Deficit Hyperactivity Disorder (ADHD), also driven by a hypo-catecholaminergic PFC. MPH elevates catecholamine levels by blocking DA and NE transporters, DAT and NET. While the potential of psychostimulants to treat post-TBI symptoms have been explored, the effects of sub-chronic MPH on transporter levels following …

How Does Schizophrenia Affect The Expression Of Alpha 7 Nicotinic Acetylcholine Receptors In The Brain?, Shruti Varshney, Nimish Acharya

Rowan-Virtua Research Day

Schizophrenia (SZ) is a psychiatric disorder with a pathophysiology that has not yet been fully understood. This mental illness is characterized by disruptions in cognition, social activity, affect, and perception, and affects approximately 0.085% of individuals worldwide. The Alpha 7 Nicotinic Acetylcholine Receptor (α7nAChR) has been connected to auditory function gating deficits. The purpose of this review is to understand the current literature in how the levels of α7nAChR expression and function are affected by SZ, information that could be used to develop therapies to modulate auditory hallucinations in patients with SZ. A literature search was conducted for peer-reviewed journal …

Efficacy Of Mcl-1 Inhibitors In Multiple Myeloma Cells Resistant To Bortezomib, Emily Nelson, Omar S. Al-Odat, Sabrina M. Paparo, Daniel A. Guirguis, Gabriella Yao, Manoj Pandey, Subash Jonnalagadda, Tulin Budak-Alpdogan

Rowan-Virtua Research Day

Multiple myeloma (MM) is a type of cancer that affects plasma B cells. Patients with MM often experience frequent relapses and can develop resistance to drugs. As a medical researcher, it is important to understand the role of Mcl-1 in preventing intrinsic apoptosis and drug resistance. Mcl-1 belongs to the anti-apoptotic subgroup of Bcl-2 family proteins and plays a crucial role in these processes. Mcl-1 plays a crucial role in driving disease progression and contributing to drug resistance in MM. It has been observed that there is an increased expression of Mcl-1 in 52% of patients with MM during diagnosis, …

The Neuroprotective Role Of Lipoxin A4 In Reinstating Blood Brain Barrier Integrity In Neuroinflammatory Disease Processes, Minjal Patel, Nimish Acharya

Rowan-Virtua Research Day

Background: The blood-brain barrier (BBB), formed by the vascular endothelium, astrocytic foot processes, pericytes, is a highly selective barrier that is responsible for maintaining brain homeostasis and ultimately proper neuronal function. Disruption of the BBB, leading to increased BBB permeability, has been reported in several neurodegenerative diseases, including Alzheimer’s disease (AD) and traumatic brain injury (TBI).¹ Loss of BBB integrity leads to the proliferation of pro-inflammatory cytokines, including TNFɑ, IL-1β, and IL-6.² Moderate inflammation has a beneficial response in the system following an acute injury. However, prolonged inflammation has been known to perturb homeostasis and have …

Pediatric Neurotropic Infection Alters Synaptic Development In The Developing Brain, Anuoluwapo Grace Fadare, Yashika S. Kamte, Manish N. Chandwani, Lauren A. O'Donnell

Rowan-Virtua Research Day

Many neurotropic viruses cause more significant pathology in younger hosts as their brains are still developing. This experiment asked how central nervous system (CNS) viral-infections affect the development of synapses in the pediatric brain during infection and post-infection. Synaptogenesis is at its peak in pediatric mice (10 days old) and we hypothesized that a neurotropic infection could disrupt synaptic proteins. We used a transgenic mouse model where measles virus (MV) infects only mature neurons, leading us to question whether synapses were impacted. We examined synaptic markers in the cerebellum and hippocampus in MV-infected and uninfected mice 9 days and 90 …

Intra-Accumbens Microinfusion Of The Dopamine D3 Receptor Partial Agonist (±)Vk4-40 Does Not Affect Basal Locomotion In Mice, Yeonwoo Sim, Nicole M. Hinds, Amy Hauck Newman, Daniel F. Manvich

Rowan-Virtua Research Day

The opioid epidemic remains a pressing public health crisis, prompting the search for alternative pharmacotherapies for Opioid Use Disorder (OUD). This study explores the potential of the dopamine D3 receptor (D3R) partial agonist, (±)VK4-40, as a novel treatment option. We investigated the impact of intra-nucleus accumbens (NAc) microinfusion of VK4-40 on basal locomotion in mice. Results indicate that VK4-40 did not significantly alter basal locomotion, suggesting that its therapeutic effects may not be mediated through disruptions in generalized motor function. Future research will focus on elucidating the neuropharmacological mechanisms underlying VK4-40's therapeutic actions and exploring its effects on psychostimulant-induced hyperlocomotion. …

Post-Mucilage Status Of The Teleost Fish Assemblages In The Sea Of Marmara, Mustafa Sari, Uğur Karadurmuş

Turkish Journal of Zoology

A frightening mucilage event occurred in the Sea of Marmara (SoM) from November 2020 to July 2021, leaving devastating effects on maritime industries, fishing activities and the benthic ecosystem. The mucilage led to intense fish mortalities, particularly affecting species like smelt, anchovy, and picarel, with severe consequences for benthic ecosystems and various marine species. This study aims to analyze the possible long-term effects of the recent mucilage disaster on species diversity and biomass by assessing the current status of teleost fish assemblages in the SoM. The data set is based on bottom trawl surveys carried out at 52 points at …

Occlusal Surface Variations In Genetically-Identified Specimens Of The Genus Apodemus (Mammalia: Rodentia) Distributed In The Northern Anatolia Region And Three Turkish Islands: Gökçeada, Marmara Island And Bozcaada, Duygu Korkmaz, Engin Selvi̇, Nuri Yi̇ği̇t, Ercüment Çolak

Turkish Journal of Zoology

A total of 134 Apodemus samples, whose genetic diagnoses had been previously conducted, were morphologically examined from 39 localities in Northern Anatolia, Thrace, Gökçeada, Bozcaada and the Marmara Island. The variation boundaries of dental variations in the distribution areas of five Apodemus species (Apodemus flavicollis, Apodemus witherbyi, Apodemus sylvaticus, Apodemus uralensis, Apodemus mystacinus) included in the research were determined. The defining morphological characters of Apodemus species, which have a complex taxonomic status, and their variations according to regions were identified using samples that had undergone genetic diagnoses. It was determined whether geographical barriers such as the Marmara Sea, the Bosphorus …

The Common Wall Lizard Podarcis Muralis (Reptilia: Lacertidae) Shows Diverse Food Preferences And Intraspecific Difference: A Study Case From Bulgaria, Emiliya Vacheva, Borislav Naumov

Turkish Journal of Zoology

The Common wall lizard (Podarcis muralis) has the largest range among the genus Podarcis. Although there are a number of studies on its diet, data on regional level remains insufficient, particularly from a purely ecological perspective. We investigated 194 individual faecal samples of P. muralis obtained from two localities in western Bulgaria with the aim of clarifying the composition of the trophic spectrum of the species, as well as the intra-population characteristics in terms of age and sex. In one study site we compared the realized trophic niche (prey items from the faecal pellets) with the fundamental (invertebrates collected via …

Sexual Size Dimorphism Of Darevskia Schaekeli (Sauria: Lacertidae), Seyyed Saeed Hosseinian Yousefkhani, Saeed Morvari

Turkish Journal of Zoology

Sexual dimorphism has been established as one of the important evolutionary results in the process of sexual selection between males and females of different species. Distinct morphological features between males and females can also be seen in reptiles. Lizards of the genus Darevskia show sexual dimorphism, as Darevskia schaekeli was studied as an example. The morphological traits investigated between males and females of this species showed that head length, trunk length, length of forelimbs and hindlimbs as well as the number of femoral pores are more in males than in females. All these morphological traits, which were more in males …

Economic Contribution Of Agriculture And Food To Arkansas' Gross Domestic Product 2017-2022, Leah English, Jennie S. Popp

AAES Research Reports and Research Bulletins

In this report, Arkansas agriculture is presented in a historical context. These data are available for 2017 through 2022. Throughout the report, agriculture is defined in terms of agricultural sectors, North American Industry Classification Scheme (NAICS) sectors, industries, and general descriptive terms that can be applied to agriculture.

Economic Contribution Of The Agricultural Sector To The Arkansas Economy In 2022, Leah English, Jennie S. Popp

AAES Research Reports and Research Bulletins

This report is the seventeenth in a series that examines agriculture’s economic contribution to the Arkansas economy. The total economic contribution of agriculture (direct, indirect, and induced effects) on value added, employment, and labor income was estimated with the Impact Analysis for Planning System (IMPLAN) for the most recent year available, 2022.

Mental Health And Traumatic Occupational Exposure In Wildland Fire Dispatchers, Robin M. Verble, Rachel Granberg, Seth Pearson, Charlene Rogers, Roman Watson

Biological Sciences Faculty Research & Creative Works

Wildland Fire Dispatchers Play a Key Role in Wildland Fire Management and Response Organization; However, to Date, Wildland Fire Studies Have Largely Focused on the Physical Hazards And, to a Lesser Extent, Mental Health Hazards of Wildland Firefighting Operational Personnel, and Dispatcher Studies Have Primarily Focused on 911 and Police Dispatchers. Studies of Other Dispatchers Have Provided Some Limited Insight into Potential Strains Impacting This Workforce, Including Work-Related Fatigue, Burnout, and Traumatic Exposure. However, the Specific Job Hazards that Are Faced by Wildland Fire Dispatchers Are Poorly Understood. in 2023, We Conducted a Cross-Sectional Survey of 510 Wildland Fire Dispatchers …

Alcohol Reward Memory In Drosophila: Investigating Changes In Neural Activity In Response To Cues Alcohol Associations And Their Role In Regulating Other Alcohol-Related Behaviors., Marieke Guitink

Honors Projects in Biological and Biomedical Sciences

With more than 200 health conditions associated with Alcohol Use Disorder, excessive drinking can take a serious toll on an individual's health, mental health, and relationships. Despite significant disruptions, there are a few treatments for Alcohol Use Disorder that support long-term abstinence. To develop effective long-term treatments for Alcohol Use Disorder, it is essential to obtain an understanding of the underlying complex changes that alcohol has on the brain, however, the complexity of the mammalian nervous system has precluded researchers from achieving this. Drosophila melanogaster is a powerful model organism for investigating how alcohol hijacks neural circuits within the brain …

Uncovering Novel Small Regulatory Rna In Protostome, Sweta Khanal

Dissertations

Small RNAs play pivotal roles in post-transcriptional gene regulation across diverse phylum of protostomes. In this study, we investigate the functional significance of atypical miRNAs, mirtron miR-1017 in Drosophila. Through ectopic expression in neuronal cells, we demonstrate that miR-1017 extends lifespan by targeting its host transcript, acetylcholine receptor Dα2, and influencing its splicing. This novel trans-regulatory function suggests a mechanism for mirtron evolution, highlighting the interplay between splicing and post-transcriptional regulation. Additionally, we profile small RNA populations in the polychaete developmental model Capitella teleta, shedding light on the small RNA landscape in annelid worms. Our analysis reveals a rich …

The Relationships Between Parental And Youth Physical Activity Behaviors And Perceptions, Bryanna Deangelis

Honors Theses

Physical activity is defined as any bodily movement by skeletal muscles resulting in energy expenditure. Physical activity has multiple different intensity levels, such as light, moderate, and vigorous. It is extremely important for both physical and mental health. The goals of this study are to examine the relationship between parental physical activity (i.e., leisure-time physical activity [moderate-vigorous physical activity]), youth health (i.e., body mass index [BMI], physical activity (moderate-vigorous physical activity), and perception of parental encouragement towards physical activity in a sample of parent-youth (8-14 years old) dyads. Participants will be sent a link via email that will have the …

Prevalence Of Mental Health Issues In Division Iii Athletes, Logan Streety

Honors Theses

College athletes have always struggled with their mental health, and it has recently become more widely recognized because of their lifestyle. Between managing schoolwork, team responsibilities, and having a social life, it is extremely easy to become overwhelmed and put other things before one’s psychological health. In this study, the SUNY Cortland Women’s Basketball team was surveyed to determine if depression, anxiety, and stress are prevalent in athletes at SUNY Cortland. The DASS-21 questionnaire was distributed to each of the women’s basketball athletes. This 21-question survey produced scores that determined whether they are experiencing symptoms of depression, anxiety, and/or stress. …

The Influence Of Music Tempo On Bench Press Power Production In College-Aged Males, Samuel Linderbaum, Reese Pantila

Applied Health Sciences Student Works

Previous research suggests that music with a tempo exceeding resting heart rate may stimulate the sympathetic nervous system (SNS), releasing catecholamines (epinephrine and norepinephrine). These hormones have physiological effects such as increased heart rate and muscle strength in cardiovascular exercise. This study aims to see if the effect of music in cardiovascular exercise is also present in strength training. This will be done by examining whether pre- and intra-exercise music listening at different tempos affects power output during bench press repetitions in young adult males. It is hypothesized that music at a higher tempo will stimulate the SNS and result …

The Effect Of Targeted Heart Rate Maximum Percentages On Cognitive Function In College-Aged Adults, Emily Snider, Izzy Smith

Applied Health Sciences Student Works

Previous research has displayed per the sympathetic nervous system (SNS), an increased heart rate (HR) is associated with higher cognitive function due to hormone and neurotransmitter release, specifically through the release of norepinephrine (NE) and epinephrine (EPI). The purpose of the present study is to examine if cognitive function defined by the Purdue PegBoard (PPB) is affected by targeted increases of HR maximum, as increased HR is stimulated by the SNS. METHODS: Twenty- eight healthy participants ages 20.82 ± 1.10 were recruited via email and enrolled in this study. Participants' targeted maximum HR was determined with the maximum HR equation …

The Effect Of Vision On Lower Quarter Balance During Y-Balance Test Testing In College Students, Nathan Smith, Katelyn Mehr

Applied Health Sciences Student Works

Purpose: In order to maintain balance and stability, the body relies on the integration of information from the visual, vestibular, and proprioceptive systems. If an individual has an impairment or weakness in one or more systems, their ability to maintain balance may be impaired. Both postural stability and vision contribute to one’s ability to maintain balance in functions of everyday life. The Y-Balance Test (YBT) is a dynamic balance assessment. This study focuses on the visual system and its relation to postural balance, specifically if altered visual states affect one’s ability to maintain balance during a YBT via the use …

Survey Of The Boletes From Fish River Nature Preserve, Noah T. Nelson

Poster Presentations

Boletes are a special kind of mushroom inside of the Kingdom Fungi that are distinguished from other mushrooms by their uniquely pored hymenium, as opposed to gills. Many boletes are ectomycorrhizal, meaning they are mutualists with vascular plants, and thus beneficial to the overall health of the terrestrial ecosystem. Some are well-known for their edibility and are of economic importance. In the United States 59 genus-level clades comprising 290 operational taxonomic units have been reported. The southeastern US and Gulf Coast regions however are less researched and recorded for their mushroom ecology. In Alabama, only 56 bolete species have been …

Gymnosperms Demonstrate Patterns Of Fine-Root Trait Coordination Consistent With The Global Root Economics Space, Jessica R. Langguth, Marcin Zadworny, Karl Andraczek, Marvin Lo, Newton Tran, Kelsey Patrick, Joanna Mucha, Luke Mccormack, Kevin E. Mueller

Biological, Geological, and Environmental Faculty Publications

Gymnosperms encompass a diverse group of mostly woody plants with high ecological and economic value, yet little is known about the scope and organization of fine-root trait diversity among gymnosperms due to the undersampling of most gymnosperm families and the dominance of angiosperm groups in recent syntheses. New and existing data were compiled for morphological traits (root diameter, length, tissue density, specific root length [SRL] and specific root area [SRA]), the architectural trait branching ratio, root nitrogen content [N] and mycorrhizal colonization. We used phylogenetic least squares regression and principal component analysis to determine trait-trait relationships and coordination across 66 …

Influence Of Vegetative Diversity During The Stocker Phase On Carcass Characteristics And Economic Returns Of Beef Steers, Sydni Borders, Jameson Brennan, Christina Bakker, Keith Underwood, Kyle Grubbs, John Jaeger, Ken Olson, Amanda Blair

Animal Science Research Report 2024

No abstract provided.

International Rice Outlook: International Rice Baseline Projections 2023-2033, A. Durand-Morat, W. Mulimbi

AAES Research Reports and Research Bulletins

No abstract provided.

Decoding Generation Z: A Perceptions Content Analysis, Olivia Larson

Agricultural Education, Communications and Technology Undergraduate Honors Theses

This thesis explores the multifaceted nature of Generation Z through a content analysis, aiming to identify the range of characteristics and preferences within this cohort. By delving beyond prevalent stereotypes, this study addresses the gap in understanding regarding Generation Z's learning styles, communication preferences, work ethics, and personal values. Through examination, this research provides insights crucial for marketers and educators seeking to engage and educate Generation Z effectively.

Dendrochronological Analysis Of The Duncan Tavern, Paris, Kentucky, Usa, Delaney Ballard, Maegen Rochner

Undergraduate Research Events

Duncan Tavern is a historical structure located at 323 High Street in Paris, Kentucky in Bourbon County. The structure currently serves as the headquarters for the Kentucky Society of the Daughters of the American Revolution (KSDAR). KSDAR maintains that Duncan Tavern was originally built in the mid-1790s; the land was purchased in 1792 by Joseph Duncan, a civilian armorer in the Revolutionary War. Although Duncan Tavern has been listed on the National Register of Historical Places since 1973, a dendrochronological study of this structure was requested to quantitatively examine the legitimacy of archival and anecdotal claims about the construction history. …

How Communities Respond To Industrial Pollution, Jacqueline Jergensen, Sara Velardi

Sustainable Communities

Industrial pollution is a growing environmental issue in the United States, having health, economic, and social consequences on the surrounding communities. This study explores how communities respond to industrial pollution by examining two case studies in New York: the Navy/Grumman Plume of Bethpage and the IBM Plume of Endicott. Document analysis provided information to create complete timelines of the pollution and remediation in each community. Interviews were also conducted to provide personal insight from residents, employees of polluting industries, or those involved with remediation efforts. Ultimately, the research suggests that industrial actors should take a proactive stance in addressing contamination. …

Acl Bracing: Is It Still Being Done Clinically And Does It Influence Confidence And/Or Biomechanical Performance During A Drop Vertical Jump?, Bailey Watson

Masters Theses & Specialist Projects

Introduction: Anterior cruciate ligament (ACL) ruptures account for 60% of sports-related injuries and the gold standard for treatment is surgical intervention to replace the damaged ligament to restore function of the ACL. Braces are typically used to return to previous physical activity levels; however, there are no clear guidelines on their utilization. Beyond the physical consequences of undergoing ACL reconstruction surgery, the psychological component is often ignored.

Purpose: The aim of this study is to better understand the impact of knee bracing on both biomechanical factors and confidence following ACL reconstruction. Two aims comprise the overarching purpose; the first is …

Effects Of Meat Attachment And Social Normative Messaging On Consumer Acceptance Of A Blended Plant-Forward Sausage Patty, Benjamin Garza

Theses & Dissertations

OBJECTIVE, The consumption of red and processed meat in the U.S. diet is rooted in psychological and social determinants. While meat alternatives (e.g., Beyond Beef) have recently entered the food and beverage market, they are not well received by consumers. The purpose of this study was to examine the effect of meat attachment and social normative messages on consumer acceptance of a blended, plant-forward meat product. METHODS. Seventy-one university students (Age: M = 22.14; Gender: Female = 52) between the ages of 18-30 years and without food allergies were recruited. This study utilized a 2 (between-subjects; social normative messages) x …

Impacts Of Urbanization On Demographics And The Stress Level Of White-Tailed Deer In The Piedmont Of South Carolina, Cameron Bramhall

Graduate Theses

Population demographics and density studies are a common way of determining number of individuals in location. Understanding how many individuals and sex ratios can help estimate total populations for future potential management practices. For white-tailed deer (Odocoileus virginianus), commonly referred to as whitetail deer, like other cervids, having too many or too few individuals in an area can cause issues. Some of the issues that may arise with too many individuals include higher disease potential, and a general lack of resources leading to an increase in competition. As areas that were once habitat for whitetail deer become more and more …