Life Sciences Commons^™

Dynamics Of Ant Activity Under Extreme Climatic Changes In 2024: Effects Of Temperature  And Humidity On Formica Rufa And Lasius Fuliginosus Behavior, Stanislav Stukalyuk, Mykola Kozyr, Vira Balabukh

Turkish Journal of Zoology

Global warming and extreme heatwaves, which can alter species distribution and ecosystem dynamics, have profound effects on forest ants. T‍his study investigated the impact of summer and autumn 2024 heatwaves on the activity, prey transport, and nest-building of Formica rufa Linnaeus, 1761 and Lasius fuliginosus (Latreille, 1798) in deciduous forests of Kyiv, Ukraine. Fieldwork was conducted from June to September 2024 in Holosiyivo Forest and the Feofaniya tract. Ant colonies were assigned to experimental plots, where logs were placed along foraging trails, or to control plots with unmanipulated ground-floor trails. The study included 10 F. rufa anthills for activity monitoring …

The Effect Of Spatial Scale Of Habitat On Abundance Of Roe Deer (Capreolus Pygargus) And Water Deer (Hydropotes Inermis Argyropus) During Summer In South Korea, Naeyoung Kim, Hyejin Kim, Hyoun-Gi Cha, Hyun-Su Hwang

Turkish Journal of Zoology

Understanding species-specific habitat preferences provides essential ecological  information about interactions among habitat components. In South Korea, roe deer  (Capreolus pygargus) and water deer (Hydropotes inermis argyropus) are the  dominant large herbivorous mammals of the family Cervidae. The increasing populations of these species have led to ecological and economic  challenges. Therefore, we investigated the effects of spatial scale characteristics on  the habitat preferences of roe deer and water deer. From June to August each year  between 2021 and 2023, we calculated the relative abundance index (RAI) using  camera-trap data and analyzed patch characteristics in the study area using remote  sensing techniques, …

The Impact Of Tgfβ Conditioning And Socs3 Expression On Cytokine Signal Transduction And Inflammatory Gene Expression In Fibroblasts, Morgan Anderson-Crannage

NYMC Student Theses and Dissertations

Inflammation is a major driver in many aspects of recessive dystrophic epidermolysis bullosa (RDEB) pathology, including impaired wound healing, fibrosis, and potentially cutaneous squamous cell carcinoma development. Fibroblasts, as key stromal cells in the dermis, are responsible for orchestrating inflammatory responses through the secretion of cytokines and chemokines upon stimulation with IL-1α or IL-6. Suppressor of Cytokine Signaling 3 (SOCS3) functions as a negative feedback regulator of cytokine signaling and has emerged as a key modulator of inflammatory responses in immune cells and fibroblasts. Transforming Growth Factor Beta (TGFβ), a known driver of fibrosis in RDEB, has been implicated in …

Assessment Of The Bioremediation Potentials Of Biosurfactant-Producing Bacterial Strains Recovered From Spent Engine Oil-Contaminated Environments In Southwest Nigeria, Nafisa Mohammed Babayola, Nasiru Bright Lecky, Chinweizu Obioma Onumaegbu, Olufunmiso Olusola Olajuyigbe, Martins Ajibade Adefisoye

Journal of Environmental Science and Sustainable Development

Environmental pollution from hydrocarbons and their derivatives is predominantly of anthropogenic origin, occurring mainly during mining, transportation, and storage. This often in an annual release of substantial amounts of pollutants into the environment. The effective restoration of petroleum-contaminated environments requires a series of interventions to remediate soil to its natural state. This study aimed to isolate and characterize biosurfactant-producing bacterial strains with potential bioremediation capabilities to assess the potential application for remediating soils polluted with spent engine oil in the Remo district, Ogun State. Bacterial isolates were recovered from soil samples collected from spent engine oil contaminated sites, using standard …

The Ecotoxicological Impact Of Polystyrene On Lissachatina Fulica: A Study Of Growth,  Pedal Mucus Histological Changes, And Protein Mucus Analysis, Atin Supiyani, Wasmen Manalu, Lina Noviyanti Sutardi, Mawar Subangkit, Andriyanto Andriyanto

Turkish Journal of Zoology

Lissachatina fulica mucin can be used as a nutraceutical agent depending on the  quality of their feed. Polystyrene (PS) waste harms soil and plants consumed by  snails, potentially affecting the quality of mucin production. This study investigated  the impact of PS on growth and mucus-producing cell characteristics as well as the  network pharmacology of mucin protein components. Fifty 5–6 cm L. fulica snails  (20–24 g) were fed organic waste (OW) and organic waste with PS (OWPS). After 28  days of ad libitum access to food, the snails’ mucus, meat, and shells were  collected and weighed. Tissue samples from the anterior …

Global Health Financing Of Diagonal Interventions: Building Resilient And Sustainable Health Systems In Sub-Saharan Africa, Lucy Kim

Master in Public Policy Theses

Background: Global health financing has historically prioritized disease-specific “vertical” programs over broader “horizontal” strengthening of general health systems. Vertical programs in HIV have led to unprecedented reductions in mortality worldwide, but HIV remains a significant public health threat in sub-Saharan Africa, where vertical strategies have long been criticized for creating fragmented health systems. In response, global health strategies have shifted towards combining vertical investments with broader horizontal activities, commonly referred to as “diagonal” programming. While evidence suggests that diagonal programming has the potential to create more resilient and sustainable health systems, evaluating its value for money is challenging due to …

Preserving The Harvest: How To Preserve Chokecherries, Callahan K. Adams, Andrea Schmutz

All Current Publications

A treasured wild fruit in Utah and across the Intermountain West, chokecherries offer both cultural heritage and culinary versatility. With proper handling and research-tested preservation methods, you can safely transform them into delicious jellies, syrups, and more. Whether using a steam juicer or stovetop method, following tested recipes and adjusting for elevation ensures both safety and quality. This fact sheet provides information and recipes to safely preserve chokecherries.

Cyanogenesis Variation In White Clover Is Decoupled From Regional Climate And Human Footprint Across A Longitudinal Gradient, Philips O. Akinwole, Yangjie Tan, Victor L. Alfonso

Biology Faculty publications

Latitudinal clines in adaptive traits are well documented, yet how such patterns translate across longitudinal gradients, where climatic variation is reduced, remains poorly understood. We investigated spatial variation in hydrogen cyanide (HCN) - a well-characterized anti-herbivore defense polymorphism governed by two independently segregating loci (Ac and Li), in white clover (Trifolium repens) across nine Midwestern U.S. cities. A total of 269 populations (4,035 individuals) were sampled along urban-rural transects, and cyanotype (cyanogenesis phenotypes) frequencies were quantified alongside regional and site-level environmental variables, including vegetation cover (NDVI), land surface temperature (LST), snow cover, impervious surface intensity, aridity, …

In Vitro Reversal Of Abc Transporter Mediated Multidrug Resistance In Human Ovarian And Non-Small Cell Lung Cancer Models, Alison K. Kellom, Pia D. Vogel

Biological Sciences Theses and Dissertations

One of the major causes of treatment failure in aggressive cancers is multidrug resistance (MDR), which is linked to the overexpression of membrane efflux proteins that export chemotherapeutics from cancer cells. This mechanism prevents chemotherapeutic drugs from reaching cytotoxic concentrations intracellularly, allowing the cancer to survive. Two primary mediators of this mechanism are P-glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP). P-gp and BCRP are transmembrane ATP-binding cassette (ABC) transporters that are frequently overexpressed in MDR cancers. They utilize the binding and hydrolysis of ATP to transport a diverse range of amphipathic molecules of varying size (Schinkel and Jonker, 2003), …

Acute And Chronic Oral Administration Of Cannabidiol-Dominant Cannabis Products: Sex- And Formulation-Dependent Effects On Anxiety-Like Behavioral Patterns In Rats, Carlos R. Maestas-Olguin

Psychology ETDs

Interest in the anxiolytic-like effects of cannabidiol (CBD), the non-intoxicating phytocannabinoid found within the genus, Cannabis, has grown significantly in recent years. However, preclinical investigations of CBD’s anxiolytic potential often elect to forgo translationally relevant models that maximize external validity in favor of greater internal and mechanistic validity. As a result, the effects of relatively low dose (< 3mg/kg) oral CBD administration on anxiety-like behaviors are not yet fully characterized. The present studies examined the impact of two orally delivered CBD-dominant cannabis products – a “full-spectrum” formulation derived from the whole plant and a CBD isolate derived from the same chemovar – on innate defensive behaviors exhibited by adult male and female rats in various tests of anxiety. Results indicated that acute and chronic low dose oral CBD administration attenuated anxiety-like behavior in rats, regardless of sex or formulation. These findings extend the growing corpus of literature describing anxiolytic-like effects of CBD.

Rhythms Of Hippocampal Function And Memory After Moderate Prenatal Alcohol Exposure, Lilliana May Sanchez

Psychology ETDs

Fetal Alcohol Spectrum Disorders involve morphologic and neurobiological abnormalities in offspring subjected to prenatal alcohol exposure. Although not as well studied as high exposure, moderate prenatal alcohol exposure represents the most common and undetected form in humans. While learning and memory deficits have been well characterized at the behavioral level in humans with Fetal Alcohol Spectrum Disorders and in animal models of moderate prenatal alcohol exposure, few studies have determined the circuit or systems level mechanisms of the behavioral deficits. A complete understanding of the neural bases of memory deficits after moderate prenatal alcohol exposure is needed to ultimately identify …

What Is Mine, Yours And Ours: Bodily Metaphor And Neuropsychology, Alicia K.E Parham

Art Theses and Dissertations

Mapping the landscape of the brain has taken human lifetimes to navigate, both structurally to understand how our biological functions interact and functionally as our thoughts and emotions shape our existence. Neurological stimulus and response inform our reality, shape our thinking, and affect our bodies in profound physiological ways. Our nervous system acts as a bridge from what we experience physically to what we feel emotionally, through the sending of electrical signals to all parts of our body.

My art practice explores the interactions of neuroscience with outside stimuli. It is rooted in the personal: learning that a neurological condition …

Characterizing A Potential Cbp/P300 Histone Acetyltransferase Homolog In Tardigrade Germline Specification And Development, Brittney Michelle Hartshorn

Honors Projects

Germline specification is a fundamental process that ensures the proper development of germ cells. Germline specification occurs either through germ cell determinants maternally inherited through the mechanism of preformation or through induction, where cell interaction and epigenetic modifications direct specification. Determining how these mechanisms evolved and diverged remains an important question in developmental biology. Despite research on germline regulation in model organisms such as Caenorhabditis elegans or Drosophila melanogaster, such regulation remains poorly understood in many other animal groups. Tardigrades are an emerging model system for investigating developmental mechanisms due to their phylogenetic placement and experimentally tractable embryos. CBP/P300 is …

Microtubules In Breast Cancer: Exploring The Α/Β-Tubulin Toggle Switch And Its Implications In Human Breast Cancer, Annemarie Ianos

Student Theses and Dissertations

Microtubules, composed of a/b-tubulin heterodimers, play a central role in breast cancer tumor growth by polymerizing, leading to metastasis and depolymerizing, contributing to proliferation. Human enzymes protein kinase Ca (PKC-a) and cyclin-dependent kinase 1 (Cdk-1) mediate phosphorylation at sites a:Ser165 and b:Ser172, respectively, influencing the growth of microtubules. It is possible that alternating phosphorylation at these sites contribute to an a/b-tubulin “toggle switch” that mediates microtubule instability and tumor growth.

The project investigates the influence of the toggle switch model on microtubule stability by determining the impact of mutants (a:S165D, a:S165N, a:S165S_P, b:S172S_P and a:S165S_P/b:S172S …

Urobiome Composition Varies With Vesicoureteral Reflux Grade And History Of Febrile Urinary Tract Infection, Theresa C. Barrett, Kelvin Li, Adam Fitch, Asha Patel, Bhanu Sharma, Jacqueline Holden, Kermina Abdelsayed, Nina N. Kowalewski, Sridhar Narla, Daniel Bushnell, Barbara A. Methé, Catherine S. Forster

Department of Medicine Faculty Papers

Vesicoureteral reflux (VUR) is a risk factor for urinary tract infection (UTI). However, data describing the urobiome in children with VUR are limited. Here, we characterized the urobiome in children with and without VUR to better understand its potential role in VUR pathogenesis. Catheterized urine samples were obtained from children who presented for voiding cystourethrogram (VCUG) between 12/1/2020 and 10/3/2023. Children were excluded if they had any surgical procedures of the genitourinary tract in the 30 days prior to VCUG or were on treatment antibiotics at the time of VCUG. 16S rRNA gene sequencing and taxonomical classification identified the urobiome. …

Reassembling Riparian Ecosystems: Stream Restoration Effects On Vegetation, Arthropods, And Aquatic-Terrestrial Connectivity, Katelyn P. Driscoll

Biology ETDs

Riparian areas exist at the aquatic-terrestrial interface and provide disproportionate ecosystem services, yet multiple stressors have degraded these zones globally. Stream restoration seeks to reverse degradation, but rigorous evaluation of treatment effectiveness remains limited. I conducted a before-after-control-impact (BACI) study in the southern Rocky Mountains to evaluate two stream restoration treatments—beaver dam analogs (BDAs) and plug-and-ponds (P&Ps)—across three dimensions of riparian ecosystem response. Using Bayesian analysis, I quantified treatment effects on functional diversity and composition of riparian plant communities. Using generalized linear mixed models, I evaluated restoration effects on riparian arthropod abundance, richness and guild composition across lateral gradients and …

The Concept 'Pollination' And Bee Pan-Trap Color And Uv Reflectance Determine The Taxonomic Compositions Of Bee Taxa Captures Across An Elevation Gradient And Seasons In The Jemez Mountains Of New Mexico, Esther A. Burton, Kelly B. Miller, Paul J. Watson, David C. Witherington, Steven Poe, David Lightfoot

Biology ETDs

This thesis examines the pollinator concept and tests how sampling methods shape bee communities. Chapter 1 provides a conceptual and philosophical analysis, arguing that pollination is a process and that pollinators are context-dependent functional roles rather than fixed taxonomic categories. It traces the concept’s development from natural history to ecological theory, introduces a dual-goal model separating plant reproduction from visitor foraging, and proposes a classification framework based on evidentiary certainty and pollination potential to resolve ambiguity in pollination research.

Chapter 2 applies these ideas empirically by evaluating how pan-trap color and ultraviolet (UV) reflectance influence bee assemblages across elevation and …

Investigating Changes In The Stable Isotopic Composition Of Juniperus Osteosperma Over 34,000 Years Of Climatic Shifts, Lisa S. Garcia

Biology ETDs

Isotopic compositions of plants from the past provides empirical evidence for paleoclimatic shifts and plants physiologically response. This study used Neotoma paleomiddens (fossilized debris piles) collected from Death Valley National Park, which contained preserved abundant plant materials. These middens range from modern to >35,000 years and capture different climatic events in Earth history. Employing Juniperus osteosperma (Utah Juniper) leaves found in middens, I investigated variation in carbon and nitrogen stable isotopic composition. To help interpret paleomidden results, we used modern field and herbaria samples of Juniperus from a spatial gradient stretching across their geographic range. Results showed δ ¹³C …

From Cranes To Clinics: Genomic Epidemiology At The Human-Animal Interface, Sarah Shrum

Biology ETDs

Emerging infectious diseases represent a significant, increasing threat to human life, economic stability, and global security. The One Health framework, which promotes human health and wellness through the understanding that animal, environmental, and human health are interwoven, is critical to understanding pathogen emergence and transmission. This is underscored by the fact that roughly 60% of all human pathogens and 75% of emerging infectious disease are zoonotic, meaning they are transmitted from animals to humans.

The work presented in this dissertation integrates genomic epidemiology, ecological analysis, and One Health Surveillance approaches to characterize cross-species circulation of opportunistic yeast pathogens (Candida …

The Effect Of Acute Hypoxia Exposure, With Exercise, On Bone Metabolic Biomarkers, Alyssa Bailly

Health, Exercise, and Sports Sciences ETDs

Hypoxic environments, resulting from decreased atmospheric partial pressure of oxygen, reduce oxygen availability in the blood and tissues, leading to a mismatch between supply and demand. This elicits several physiological adaptations and may influence bone metabolism. Although evidence suggests that hypoxia can modulate bone remodeling through hypoxia-inducible pathways, findings remain mixed, with most data derived from chronic hypoxic exposures in animal and cell culture models. Exercise, an essential stimulus for bone health, may exacerbate hypoxic stress; however, the skeletal response to acute hypoxic exposure combined with exercise remains unclear. We propose that intermittent exercise in hypoxia may increase negative markers …

Computational Design Of Peptides And Proteins Through Machine Learning Approaches, Emily J. Hendrix

Chemistry and Chemical Biology ETDs

Advancements in machine learning have emerged as a pivotal tool in computational biochemistry, offering new advancements to address challenges in protein structure and function. However, current machine-learning approaches offer limited insight in understanding protein dynamics. The purpose of this work is to combine traditional physics-based computational tools, such as molecular dynamics and coarse-grained simulations, with recently developed AI-driven computational tools to bridge gaps and advance the understanding of proteins in both structural and dynamic aspects. I investigated several approaches such as (i) traditional physics-based methods to study protein conformation and ensembles; (ii) identifying a peptide inhibitor for the PICK1 PDZ …

Influence Of The Discipline Of Authentic Movement Practice On Interpersonal Relationships, Joy Ruben Welts

Educational Studies Dissertations

This mixed methods study explored how practicing the Discipline of Authentic Movement impacts relationships. This research was conducted to fill in the gaps around attunement and use of the Discipline of Authentic Movement as an intervention to support healthy relationships. Five self-selected adults met on Saturday afternoons for eight weeks to practice the Discipline of Authentic Movement. They completed a pre and post Revised Adult Attachment Scale and reflected weekly on their experience through journaling. Participants reported that it was the structure of the Discipline of Authentic Movement that allowed them to feel more comfortable being themselves with others. The …

Harnessing Mechanobiology Of Resident Stem Cells To Refine Cell Based Therapeutics, Dakota R. Kamm

WUSM Theses and Dissertations – All Programs

Mesenchymal stem cells (MSCs) are resident cells residing with many adult tissues such as adipose tissue and bone marrow that have the potency for multiple lineage differentiation as well as the capacity to secrete a litany of beneficial factors to maintain homeostasis and promote tissue repair. Since 1995, MSCs have been used therapeutically to treat a variety of conditions from osteoarthritis to heart disease to muscle pathologies. Great leaps have been made in improving MSC-based therapies through optimization of culture methods and select enrichment of cellular subpopulations. More recently, the physical microenvironment of tissue in vivo and culture conditions in …

Exploring The Biological Basis For Exercise Neuroprotection In Parkinson’S Disease: A Cross-Sectional Study Of Exercise And Physical Activity On Inflammatory Cytokines And Neurotrophins, Leah Isabelle P. Alegre, Jacob M. Brewer, Adeline Florschutz, Kate E. Hamiltonthompson

UNLV Theses, Dissertations, Professional Papers, and Capstones

Regular exercise and physical therapy are known to increase production of neurotrophins, including brain-derived neurotrophic factor (BDNF), and anti-inflammatory cytokines. These changes combine to theoretically protect and slow the progressive loss of neurons in Parkinson’s disease (PD). The purpose of this study was to examine the effect of exercise and physical activity on various anti-inflammatory and pro-inflammatory cytokines and neurotrophins in people with PD (PwP). This was a cross-sectional design involving PwP (n=37), aged 43-85 years, who participated in two 30-minute bouts of exercise (with brief rest breaks during and pre/post blood draws) separated by a week. Measures collected prior …

Effects Of Melatonin Supplementation On Exercise Induced Stress In Horses, Hannah Clark Valigura

Theses and Dissertations

Exercise is a necessary component of athletic conditioning but imposes substantial physiological stress on horses, resulting in oxidative stress, inflammation, muscle damage, and thermal strain that can impair performance and recovery. Melatonin, a neurohormone with potent antioxidant and thermoregulatory properties, has been proposed as a novel nutritional strategy to mitigate these effects. This dissertation aimed to (1) characterize serum melatonin concentrations following oral supplementation, (2) evaluate the effects of melatonin on oxidative stress, inflammation, and muscle damage biomarkers after exercise, and (3) examine its influence on physiological parameters during exercise under warm weather conditions. Across a series of controlled experiments …

Community Development Professionals’ Perceptions Of Agritourism In Mississippi, Emma Jane Berry

Theses and Dissertations

Agritourism has emerged as a strategy for supporting rural economies, strengthening community identity, and increasing agricultural literacy. Although prior research has examined agritourism operators and visitors, limited attention has been given to the perceptions of community development professionals who influence local planning and program support. The purpose of this qualitative exploratory study was to examine community development professionals’ perceptions of agritourism’s role in community development, economic growth, and agricultural literacy in Mississippi. Guided by Social Exchange Theory, data were collected through two semi-structured virtual focus groups with 12 professionals representing Extension, tourism, economic development, and Main Street organizations. Data were …

Cytokinins, Gibberellins, And Ethylene On Plant Form And Flowering In Streptocarpus, Rachel Bobo

Theses and Dissertations

Plant form and flowering of Streptocarpus x hybridus Ladyslippers® ‘Grape Ice’ and ‘Deep Blue Vein’ were examined in response to exogenous application of ethephon [(2-chloroethyl) phosphonic acid], gibberellin 3 (GA3), benzyladenine (BA), and growth retardants ancymidol and chlormequat chloride. 750 mg L-1 ethephon applied at 3 weeks post-transplant (WPT) is effective in chemically pinching premature floral buds, delaying flowering by up to 10 days without restricting final plant size. Early applications of GA3 and BA hasten flowering by up to 10 days. GA3 and BA also interacted to promote floral development when applied early in the production cycle; increasing flower …

Determining Agricultural Literacy Proficiency Of Extension Professionals And Primary Volunteers In Mississippi, Molly Campbell

Theses and Dissertations

The development of agricultural literacy is a lifelong process, moving from gaining agricultural knowledge to communicating with others to applying to societal issues, and extends beyond the formal classroom. The Mississippi State University Extension Service has the ability to reach various audiences through educational programming, making them a potential catalyst for change in increasing agricultural literacy across the state. The study aims to determine the agricultural literacy levels of Extension professionals and primary volunteers in Mississippi and the factors potentially influencing these levels. Twenty-nine Extension professionals and eleven primary volunteers completed a survey of demographic questions and the Judd-Murray Agricultural …

The Development And Evaluation Of An Automated Tactical Tillage Tool To Identify And Control Weeds In Row-Crop Production Systems Using Vision-Based Machine Learning., Clara Anne Cobb

Theses and Dissertations

Controlling in-field weeds in row-crop production systems is vital to the success of the operation. To control weeds, most producers use combinations of weed control strategies, including tillage and herbicide applications. Cotton production operations across the country have been trending toward conservation tillage practices in an effort to minimize soil disruption and maintain crop residues on the soil surface. This practice, in addition to the adoption of herbicide-tolerant cotton varieties, has encouraged more use of chemical herbicides. The overuse of these herbicides has resulted in an increase in herbicide-resistant weeds, making weed control difficult for farmers. This research aimed to …

From Miocene Origins To Ecological Diversification: Unraveling Evolutionary Dynamics Of North American Asters (Symphyotrichum), Sushil Dahal

Theses and Dissertations

Symphyotrichum, a plant genus traditionally treated within the genus Aster L., comprises >100 species of annual or perennial plants in the Compositae family Asteraceae. One of the most diverse genera in the southeastern US flora, the genus extends across the Americas, the Caribbean as well as eastern Eurasia. Despite its presence across the major American biomes and with distinctive floristic characteristics, several question regarding Symphyotrichum remains obscure. This research project focuses on exploring diverse aspects of Symphyotrichum systematics, biogeography and evolution. I tested three main hypotheses: (1a) Symphyotrichum originated ancestrally across Mexico and eastern North America in the Miocene ( …