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Articles 17971 - 18000 of 256002
Full-Text Articles in Life Sciences
Kinetic Model Of Glycolysis And Glutaminolysis Interplay Developed In Matlab Simbiology, Zohreh Mirveis, Hugh J. Byrne, Nitin Patil
Kinetic Model Of Glycolysis And Glutaminolysis Interplay Developed In Matlab Simbiology, Zohreh Mirveis, Hugh J. Byrne, Nitin Patil
Datasets
This dataset contains a kinetic model developed in MATLAB SimBiology to simulate the metabolic dynamics of glycolysis and glutaminolysis and their interconnection. The model was used in the study ‘Experimental and computational investigation of the kinetic evolution of the glutaminolysis pathway and its interplay with the glycolysis pathway’ (Mirveis et al., 2024). The dataset includes the original SimBiology project file together with the experimental data used for model training. These resources enable reproduction of the simulations reported in the publication and provide a reusable framework for further computational exploration of metabolic pathway kinetics.
Broiler Breeders Today: Feather Development And Nutrition, Justina Caldas
Broiler Breeders Today: Feather Development And Nutrition, Justina Caldas
Proceedings of the Arkansas Nutrition Conference
The broiler industry in the US has observed a consistent decline in fertility and hatchability, particularly the past 5 years. There are numerous managerial and nutritional approaches to optimize the pullet and subsequent mature broiler breeder, and these proceedings focus on feathering. Moreover, these proceedings examine the quantity and quality of broiler breeder plumage as affected by both pullet and hen nutrition.
Near-Infrared Hemicyanine And Bodipy Sensors For Monitoring Mitochondrial Viscosity In Live Cancer Cells, Drosophila Melanogaster Larvae, And Adpkd Kidney Tissue, Joseph Peters
Dissertations, Master's Theses and Master's Reports
Two near-infrared fluorescent sensors, sensor A and sensor B, were synthesized and characterized. Sensor A was a hemicyanine derived structure, and sensor B was a BODIPY derived sensor. The sensors were tested to measure their ability to monitor viscosity, and sensor A was used to monitor viscosity in live cells. Both sensors were found to be effective in monitoring the viscosity level through optical measurements with glycerol. Sensor A was found to be successful in monitoring mitochondrial viscosity in HeLa MBA-MD-453 and MDA-MB-231 cell lines. It was also successful in monitoring viscosity in Drosophila melanogaster larvae as well as …
Hybrid Mixtures Of Factor Analyzers For High Dimensional Data, Kazeem Abiodun Kareem
Hybrid Mixtures Of Factor Analyzers For High Dimensional Data, Kazeem Abiodun Kareem
Dissertations, Master's Theses and Master's Reports
Factor analysis is a powerful tool for modeling latent structures in high-dimensional data, traditional approaches assume a single global structure, limiting their ability to capture heterogeneity. The Mixture of Factor Analyzers (MFA) extends classical factor analysis by modeling data as a mixture of Gaussian-distributed local subspaces, effectively uncovering cluster-specific latent structures. However, MFA relies on Gaussian mixtures, making it sensitive to outliers and ill-suited for heavy-tailed data. The Mixture of $t$-Factor Analyzers (M$t$FA) addresses these limitations by incorporating multivariate $t$-distributions, improving robustness. Despite their advantages, both MFA and M$t$FA face significant computational challenges in high-dimensional settings, particularly due to costly …
Initial Fungal Decomposer Community Determines Wood-Derived Carbon In Discrete Soil Carbon Pools In Aspen Clearcuts, Theresa K. Meyer
Initial Fungal Decomposer Community Determines Wood-Derived Carbon In Discrete Soil Carbon Pools In Aspen Clearcuts, Theresa K. Meyer
Dissertations, Master's Theses and Master's Reports
Soil carbon storage can be affected by forest management activities that alter the amount of biomass at a site, including slash retention and salvage harvesting. Initial fungal colonization of retained biomass may affect soil carbon storage due to differences in fungal decomposition strategies. To examine the effect of wood addition on wood-derived soil carbon storage and the interaction between initial fungal decomposer communities and wood application depth, δ13C modified wood inoculated with white- or brown-rot fungi was applied to soils across Michigan’s Upper Peninsula. Wood-derived carbon was assessed after 3.5 years in bulk soil samples and in three …
Patient Handling Interventions And Their Role In Reducing Musculoskeletal Disorders Among Healthcare Workers, Ashley L. Hawke
Patient Handling Interventions And Their Role In Reducing Musculoskeletal Disorders Among Healthcare Workers, Ashley L. Hawke
Dissertations, Master's Theses and Master's Reports
Musculoskeletal disorders (MSDs) are prominent among healthcare professionals, especially those who perform manual patient handling tasks. Assistive devices (e.g., slider sheet, gait belt, mechanical lift) have been used for patient handling. However, the effectiveness of these devices in reducing MSD risk factors is varied. Additionally, the relationship between healthcare workers’ acceptability of patient handling devices and organizational policies that facilitate or hinder widespread implementation is not well understood. The goal of my dissertation was to conduct a comprehensive analysis of existing patient handling devices and their role in mitigating MSD risk among healthcare workers. For Study 1, I conducted a …
Design And Development Of Fluorescent Probes For Sensing And Bioimaging Of Nad(P)H, Intracellular Viscosity, And So2, Dilka Liyana Arachchige
Design And Development Of Fluorescent Probes For Sensing And Bioimaging Of Nad(P)H, Intracellular Viscosity, And So2, Dilka Liyana Arachchige
Dissertations, Master's Theses and Master's Reports
Understanding the dynamic biochemical and biophysical changes within living systems is vital for advancing disease diagnosis and therapeutic development. This work presents the design and development of innovative fluorescent probes, based on cyanine and coumarin scaffolds, for the highly sensitive and selective detection of key metabolic and biophysical markers, NAD(P)H, mitochondrial viscosity, and sulfur dioxide (SO₂) in live cells and fruit fly larvae. A series of cyanine-based probes were engineered to undergo strong fluorescence enhancement upon reduction by NAD(P)H, enabling real-time visualization of metabolic fluctuations in cancer cells and Drosophila larvae. These probes exhibit excellent sensitivity, mitochondrial targeting capability, and …
Karyotyping As A Method To Verify Phylogenetic Relationships Among The Enneacanthus Species, Ophelia A. Anderson
Karyotyping As A Method To Verify Phylogenetic Relationships Among The Enneacanthus Species, Ophelia A. Anderson
Theses and Dissertations
The Enneacanthus genus consists of three species of freshwater fish endemic to eastern North America: E. obesus (Banded Sunfish), E. gloriosus (Blue Spotted Sunfish), and E. chaetodon (Black Banded Sunfish). Previous studies using molecular data suggest that E. obesus and E. gloriosus are more closely related, with E. chaetodon as the most distantly related species in the genus. This study investigates the phylogenetic relationship among the Enneacanthus species, using karyotype characteristics - chromosome number, morphology and fundamental number - as comparative metrics. Chromosome spreads were obtained from scale and gill epithelium samples collected between 1993 and 1994. Prepared slides …
Caspases Protect Against Hyperglycemia Induced Necroptosis-Like Cell Death In Brain Endothelial Cells, Aleena S. Mathew
Caspases Protect Against Hyperglycemia Induced Necroptosis-Like Cell Death In Brain Endothelial Cells, Aleena S. Mathew
Theses and Dissertations
Acute diabetes characterized by high spikes in blood glucose levels in association with severe hyperglycemia can lead to an increased risk of ischemic stroke in the brain. To better understand high blood glucose levels, hyperglycemia, in the brain we explored its effects on endothelial cells. Endothelial cells line the inner walls of blood vessels and are directly impacted in hyperglycemia. Brain endothelial cells are a major component of the blood brain barrier (BBB) which tightly regulates the brain’s microenvironment. The type of cell death such as apoptosis, caspase dependent, or necroptosis, caspase independent, can exacerbate diabetes associated complications. There is …
Chromosome Segregation Dynamics During Meiosis I, Meiosis Ii, And Mitosis Cell Divisions In Acheta Domesticus (House Crickets), Sweta Aryal
Master’s Theses
Chromosomes exhibit diverse types of organization and movement during the cell division process. Meiosis is essential for sexual reproduction, producing haploid cells from diploid precursors. In meiosis I, homologous chromosomes pair up, and separate in anaphase I, with two chromatids moving toward each pole. In meiosis II, the sister chromatids move to opposite poles during anaphase II and produce haploid cells. In contrast, in mitosis, the chromosomes are copied and distributed to produce genetically identical diploid somatic cells. Understanding the behavior of chromosomes during mitosis and meiosis is significant for accurate chromosome segregation to prevent birth defects and diseases like …
Evaluation Of Sex Trivalent Chromosome In Giant Shield Mantis (Rhombodera Megaera) And Holocentric Chromosome In Milkweed Bug (Oncopeltus Fasciatus), Hedyeh Davoudi Kianersi
Evaluation Of Sex Trivalent Chromosome In Giant Shield Mantis (Rhombodera Megaera) And Holocentric Chromosome In Milkweed Bug (Oncopeltus Fasciatus), Hedyeh Davoudi Kianersi
Master’s Theses
Aneuploidy, which refers to the abnormal number of chromosomes within a haploid set, has a significant effect in both physical and cognitive process of development. Proper chromosome segregation during cell division is crucial to prevent aneuploidy. Chromosome segregation is affected by the alignment of chromosomes on the metaphase plate as well as the position of centromere on the chromosome. Many arthropod species have sex chromosomes that either naturally are unpaired or pair in ways that differ for the usual patterns for autosomes. Also, some arthropods possess unique centromere position on their chromosomes which directly affects chromosome segregation pattern. Evaluating the …
Analysis Of Sled Dog Biomechanics, Natalie Bender
Analysis Of Sled Dog Biomechanics, Natalie Bender
Williams Honors College, Honors Research Projects
This paper is an analysis of data collected by Dr Rachel Olson and her team. The data was collected from the same set of sled dogs before and after training for the Iditarod race. The goal of this paper is to draw conclusions on whether the gait of sled dogs’ change with fitness level. The data was cleaned in R to find the average peak for forelimb joint angles per run for each dog. The data was analyzed with 3 different ANOVAs – one including both the shoulder and carpus, one for just the shoulder, and one for just the …
Effects Of Energy Drinks On Crayfish Physiology, Melyna Sweeney
Effects Of Energy Drinks On Crayfish Physiology, Melyna Sweeney
Williams Honors College, Honors Research Projects
Energy drinks have become the drink of choice among many college students due to the rush of energy it provides via the megadose of caffeine (Vercammen et al. 2019). Because of their newfound popularity, there is much research to be done about the effects on human physiology. Energy drinks are known to increase endurance in muscles of rat subjects (Imagawa et al. 2009) and stimulate enhanced “alertness” (Smit & Rogers, 2002). The purpose of this research was to uncover the potential effects that energy drinks have on metabolic rate and/or stress responses in crayfish (Procambarus clarkii), with the …
Statistical Approaches In Evolutionary Biology: Using Threespine Stickleback Fish To Test Fisher's Geometric Model And Evaluate Methods For Handling Missing Data, Aaron Mathew Myrold
Statistical Approaches In Evolutionary Biology: Using Threespine Stickleback Fish To Test Fisher's Geometric Model And Evaluate Methods For Handling Missing Data, Aaron Mathew Myrold
Dissertations
This thesis explores two distinct yet complementary aspects of evolutionary biology. The first chapter tests predictions from Fisher's geometric model of adaptation using a finely resolved fossil sequence of Gasterosteus doryssus spanning approximately 21,250 years. I analyze phenotypic changes in three armor traits during adaptation to a new environment and find that while step sizes follow the predicted exponential distribution—with many small steps and few large ones—they do not adhere to the model's temporal prediction that large-effect mutations should fix early in the adaptive walk. This discrepancy likely reflects adaptation from standing genetic variation rather than de novo mutation. The …
Genetic Architecture Of Complex Traits In African Ancestries Across Diverse Environments, Isadore Gregga
Genetic Architecture Of Complex Traits In African Ancestries Across Diverse Environments, Isadore Gregga
Dissertations
Given genetic and environmental diversity, genetic prediction based on African- ancestries individuals in the US or UK may not transfer well to other African diaspora regions. The Modeling the Epidemiological Transition Study (METS) is a longitudinal study of cardiometabolic health in five African-ancestry populations. We performed genome-wide genotyping in METS participants from the US, Jamaica, South Africa, and Ghana. We aimed to explore how genetic models for the transcriptome and body mass index (BMI) built using US- based African-ancestries populations perform in these four diverse populations. A subset of METS participants also had whole blood RNA-Seq data. For these, we …
Interactions Between Microplastics, Biofilms, And Antimicrobials In Freshwater Streams, Ryan Thomas Krantz
Interactions Between Microplastics, Biofilms, And Antimicrobials In Freshwater Streams, Ryan Thomas Krantz
Dissertations
Microplastics (MPs) are ubiquitous contaminants in freshwater ecosystems that could be hotspots for the interaction of antimicrobial compounds and surface-attached microbial biofilm communities. MPs and antimicrobials are both common in wastewater and urban freshwaters and MPs can adsorb contaminants like antimicrobials to their surface. Within aquatic habitats, MPs also support colonization by microbial biofilms. Therefore, we hypothesized that the adsorption of antimicrobials to MP surfaces would affect microbial communities colonizing MPs, altering their diversity, composition, and antimicrobial resistance. We investigated the effects of these interactions across two studies. The first study, discussed in Chapter 2, used a microcosm approach to …
Management Adaptations To Sustainably Increase Soybean Yield And Water Productivity Through Field Studies And Crop Modeling, Mounica Talasila
Management Adaptations To Sustainably Increase Soybean Yield And Water Productivity Through Field Studies And Crop Modeling, Mounica Talasila
Theses and Dissertations--Plant and Soil Sciences
Soybean (Glycine max [L.] Merr.), a major crop in the upper U.S. Mid-South, is predominantly cultivated under rainfed conditions, where variable precipitation frequently induces water stress and limits yield potential. Consequently, irrigation adoption has been increasing across this region. Determining the optimal cultivar maturity group (MG) and planting date (PD) for both rainfed and irrigated systems is essential for maximizing yield and improving water use metrics. Evaluating crop water use efficiency (WUE; yield per unit of seasonal evapotranspiration) and total water productivity (WP; yield per unit of total water input from precipitation and irrigation) is critical to developing such …
Distinct Odorant Receptor Response Patterns To Aliphatic Odorants In Freely Behaving Mice, Claire A. De March, Patrick Breheny, William B. Titlow, Hiroaki Matsunami, Timothy S. Mcclintock
Distinct Odorant Receptor Response Patterns To Aliphatic Odorants In Freely Behaving Mice, Claire A. De March, Patrick Breheny, William B. Titlow, Hiroaki Matsunami, Timothy S. Mcclintock
Physiology Faculty Publications
In mammals, odors are encoded by a combinatorial code determined by the pattern of responses across hundreds of odorant receptors expressed monogenically and monoallelically in olfactory sensory neurons. The compositions of these receptor response patterns are largely unknown and overlap between them has yet to be explored. Activity-dependent reporter gene expression in freely behaving S100a5-tauGFP mice allowed capture of activated olfactory sensory neurons and identified 168 receptors responsive to moderate concentrations of 1 or more of 12 aliphatic (5 to 8 carbons) ketones, alcohols, and carboxylic acids. These 12 response patterns are remarkably different, with only 19% of the receptors …
Feeding- And Light-Cycle Synergistically Regulate Mouse Blood Pressure Daily Rhythm Via Bmal1-Dependent And Independent Mechanisms, Tianfei Hou, Wen Su, Aaron Chacon, An-Hsuan Lin, Zhenheng Guo, Ming C. Gong
Feeding- And Light-Cycle Synergistically Regulate Mouse Blood Pressure Daily Rhythm Via Bmal1-Dependent And Independent Mechanisms, Tianfei Hou, Wen Su, Aaron Chacon, An-Hsuan Lin, Zhenheng Guo, Ming C. Gong
Physiology Faculty Publications
Cardiovascular health requires the orchestration of the daily rhythm of blood pressure (BP), which responds to changes in light exposure and dietary patterns. Whether rhythmic light and feeding can modulate daily BP rhythm directly or via modulating intrinsic core clock gene Bmal1 is unknown. Using inducible global Bmal1 knockout mice (iBmal1KO), we explored the impact of rhythmic light, rhythmic feeding, or their combination on various physiological parameters. Daily rhythms of BP, heart rate, and locomotor activity were monitored via radiotelemetry, while food intake patterns were tracked using the BioDAQ system. Respiratory exchange ratio (RER) and energy expenditure (EE) were assessed …
Targeting Als: A Multi-Cellular Study On The Potential Therapeutic Role Of Azole-Based Compounds, Alisha R. Kennedy
Targeting Als: A Multi-Cellular Study On The Potential Therapeutic Role Of Azole-Based Compounds, Alisha R. Kennedy
Theses and Dissertations
Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s disease, is a progressive neurodegenerative disorder that leads to the degeneration of motor neurons, which control voluntary muscle movements such as eating, speaking, and breathing. As these neurons are damaged, voluntary movement ceases, leading to a fatal outcome. The survival time of ALS patients varies, ranging from a few months to up to 10 years. Chapter 1 of this thesis provides an overview of ALS, highlighting the role of transactive response DNA-binding protein 43 (TDP-43), a key feature in ALS and other neurodegenerative diseases. The aggregation of TDP-43, particularly due to …
Estrogen Receptor-Mediated Effects Of Resveratrol On Muscle Function, David Ayi-Bonte
Estrogen Receptor-Mediated Effects Of Resveratrol On Muscle Function, David Ayi-Bonte
Open Access Master's Theses
Artemis missions are set to send the next man and the first woman back to the moon and enable long-term missions on the lunar surface. However, exposure to lunar gravity has significant physiological effects characterized by loss of muscle mass, weakness and decreased bone density. Nutraceutical countermeasures such as Resveratrol (RSV), a naturally occurring polyphenol, have been identified as promising strategies to preserve musculoskeletal health; however, its pleiotropic effect hinders our ability to identify the primary cellular pathways through which it delivers its benefits. Furthermore, its efficacy in simulated lunar gravity is unknown. Based on the benefits observed with RSV …
Evaluation And Treatment Of Baseball Pitchers: There’S More To Assess Than The Arm, Matthew L. Gauthier, Casey A. Unverzagt, George J. Davies
Evaluation And Treatment Of Baseball Pitchers: There’S More To Assess Than The Arm, Matthew L. Gauthier, Casey A. Unverzagt, George J. Davies
Physical Therapy Faculty Publications
Injuries are commonplace in the overhead athlete, with many occurring to the shoulder and elbow. The increasing prevalence of injuries to the shoulder and elbow has been discussed at length in recent years, with increased research focus being placed on arm care for rehabilitation and prevention strategies. Even though the pitching motion is well-established as a whole-body kinetic chain movement, most attention in rehabilitation and prevention efforts is often placed on the upper extremity. The purpose of this clinical commentary is to highlight the impact the lower extremity and trunk have on the upper extremity during the throwing motion, better …
Mercury Concentrations, Health, And Marine Food Consumption Across Four Eastern Caribbean Populations: Insights From A Novel Community-Based Study, Russell Fielding, Catherine Brown, Jessica Dutton, Martin S. Forde, Heather Harewood, Lisa Hunt, Catherine Macdonald, Cameron Mewhirter, Vincent Reid, Madison Smith, Holly Taylor, Katelyn Zimmerman
Mercury Concentrations, Health, And Marine Food Consumption Across Four Eastern Caribbean Populations: Insights From A Novel Community-Based Study, Russell Fielding, Catherine Brown, Jessica Dutton, Martin S. Forde, Heather Harewood, Lisa Hunt, Catherine Macdonald, Cameron Mewhirter, Vincent Reid, Madison Smith, Holly Taylor, Katelyn Zimmerman
Gulf and Caribbean Research
Mercury (Hg), as an environmental pollutant, can have harmful effects on human health. A common way that people are exposed to Hg is through seafood consumption. This project was designed to investigate Hg exposure through seafood consumption and its health effects among adults in 4 Caribbean countries: Barbados (n = 117), Grenada (n = 90), St. Lucia (n = 126), and St. Vincent & the Grenadines (n = 77). We applied a novel, community—based method, which involved recruiting and paying local barbers and hairstylists to collect hair samples from their clients who consented to join the project as participants. Participants …
The Role Of Post-Cloacal Gland Biofluorescence In Male-Male Communication In Plethodon Cinereus, Kasey Watterson
The Role Of Post-Cloacal Gland Biofluorescence In Male-Male Communication In Plethodon Cinereus, Kasey Watterson
Masters Theses
Biofluorescence is increasingly recognized as a potentially important form of visual communication across a wide range of taxa, yet its ecological and behavioral function remains largely untested in many terrestrial species. In the red-backed salamander (Plethodon cinereus), fluorescence is a sexually dimorphic trait most strongly expressed in males, particularly around the cloacal region and ventral side of the tail, areas that are often displayed during territorial contests and courtship. Rival males also direct behaviors like cloacal investigation toward these fluorescent regions, suggesting a potential signaling function. Since fluorescence is often displayed during territorial contests, I hypothesized that fluorescence in male …
Cloning, Expression, And Characterization Of Collagen Galactosyltransferases From Human, Sponge, And Sea Walnut, Jeong Seon Kim, Tingfei Chen, Botao Zhang, Tristin M. Miller, Marisa E. Gilliam, Houfu Guo
Cloning, Expression, And Characterization Of Collagen Galactosyltransferases From Human, Sponge, And Sea Walnut, Jeong Seon Kim, Tingfei Chen, Botao Zhang, Tristin M. Miller, Marisa E. Gilliam, Houfu Guo
Molecular and Cellular Biochemistry Faculty Publications
Collagen is an extracellular matrix protein conserved across animals and viruses, with its function regulated by post-translational modifications of lysine residues. Specifically, certain lysine residues in collagen are hydroxylated to form hydroxylysine, which serves as an attachment site for hydroxylysine-linked glycosylation. This glycosylation process is initiated by collagen galactosyltransferases from the GT25 family, also known as GLT25D or COLGALT proteins. Despite their biological importance, efficient methods for expressing and isolating GLT25Ds have yet to be fully developed, and the biochemical mechanisms underlying their function still need to be better understood. To address this, we performed sequence alignment and phylogenetic analyses …
Perceptions Of Plant-Based Meat And Cultured Meat Within The Northern Great Plains Region, Donald Chase Stehly
Perceptions Of Plant-Based Meat And Cultured Meat Within The Northern Great Plains Region, Donald Chase Stehly
Dissertations and Theses
Conventional meat consumption derived from livestock farming is one of the leading causes of greenhouse gas emissions and environmental degradation on our planet. Substituting conventional meat products with “meat alternatives” such as plant-based meat or cultured meat would drastically decrease greenhouse gas emissions, reduce land and water pollution, and decrease land and water usage. However, it is necessary to first gauge how people feel about eating plant-based meat and cultured meat before it is possible to discern the magnitude of environmental benefits that occur with a significant dietary change such as this. By administering a questionnaire to over 400 participants …
Valorizing Municipal Solid Waste For Sustainable Aviation Fuel And Polyhydroxyalkanoate Bioplastics: Pyrolysis And Microbial Pathways, Emon Das
Theses and Dissertations--Biosystems and Agricultural Engineering
The escalating global burden of municipal solid waste (MSW), projected to reach 3.88 billion tons annually by 2050, calls for innovative valorization strategies to mitigate environmental impacts and promote a circular bioeconomy. This thesis investigates the conversion of MSW into two high-value products: sustainable aviation fuel (SAF) and polyhydroxyalkanoate (PHA) bioplastics. Chapter one presents comprehensive physicochemical characterization and pyrolysis-GC/MS analysis of MSW feedstocks. The physicochemical results reveal that densification enhances handling and storage properties, while pyrolysis-GC/MS analysis indicates that plastic-rich MSW streams produce bio-oils with favorable hydrocarbon profiles suitable for SAF production, potentially contributing to decarbonization efforts in the aviation …
Mangroves: A Lesson On Modeling Changing Shorelines, Willa Skye
Mangroves: A Lesson On Modeling Changing Shorelines, Willa Skye
ENGS 15.11: Design and Education
This lesson is an overview of storm barriers, specifically mangroves and how they maintain shorelines. It is meant to offer a visual experience of coastline protection and provide a background for deeper understanding about intertidal zones and their conservation. Students will spend time creating a solution to a flooding problem by making a mock coast and storm barrier. To wrap-up the lesson, students will pair up, then reflect on their model and then individually write or draw their takeaways.
Confronting Indecision, Lane Allison Murray
Confronting Indecision, Lane Allison Murray
ENGS 15.11: Design and Education
This course aims to increase students' understanding of indecision and how to confront it. The class provides insight into how the fear of the unknown holds people back from making decisions and about understanding one's values as a means to combat indecision. Students and teachers alike explore instances of indecision and evaluate their own impulses & thought processes by reflecting on the deeper reasons for their choices. Students will increase their comfort level of asking themselves and their peers questions about the values that guide them and, in doing so, strengthen their relationships with themselves and others.
The Role Of Chronic Activity-Based-Anorexia In Drug-Paired Environmental Preference, Abby Bendixen
The Role Of Chronic Activity-Based-Anorexia In Drug-Paired Environmental Preference, Abby Bendixen
Behavioral Neuroscience Honors Papers
Anorexia nervosa (AN) has one of the highest mortality rates among psychiatric disorders. This disorder, and other eating disorders, have features that overlap with substance use disorder (SUD), including reward sensitivity, impulsivity, and emotional dysregulation. The purpose of this study was to investigate the role of chronic, restrictive eating disorders on the development of cocaine-paired environmental preference. Seven-week-old female rats were induced to a model of chronic activity-based-anorexia (ABA) and underwent conditioned place preference (CPP) testing to examine cocaine-paired environmental conditioning. The activity patterns of rats that underwent chronic ABA were not consistent with previous studies inducing chronic ABA in …