Open Access. Powered by Scholars. Published by Universities.®

Life Sciences Commons™

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 14251 - 14280 of 255729

Full-Text Articles in Life Sciences

Analyzing The Inhibition Of Chemical Compounds On Collagenase In P. Aeruginosa, Elaine Vanterpool Apr 2025

Analyzing The Inhibition Of Chemical Compounds On Collagenase In P. Aeruginosa, Elaine Vanterpool

Student Posters

Pseudomonas aeruginosa is an opportunistic pathogen that poses significant challenges in clinical treatment due to its production of collagenase. This bacterium can cause several infections including pneumonia, meningitis, septicemia, and a host of other diseases. Collagenase acts as a key virulence factor by breaking down collagen in the host’s extracellular matrix, allowing bacteria to invade tissues. This study hypothesized that the effects of cell secreted collagenase would be inhibited by metronidazole, vanillin, and silver nanoparticles to reduce the pathogenicity of Ps. aeruginosa related infections. With the use of a spectrophotometric assay, collagenase activity was measured in treated and untreated bacterial …

Go to article

Steroid Receptors And Coregulators: Dissemination Of Sex Differences And Emerging Technologies, Sally Pauss, Evelyn A. Bates, Genesee J. Martinez, Zane T. Bates, Zachary A. Kipp, Cassandra D. Gipson, Terry D. Hinds Jr. Apr 2025

Steroid Receptors And Coregulators: Dissemination Of Sex Differences And Emerging Technologies, Sally Pauss, Evelyn A. Bates, Genesee J. Martinez, Zane T. Bates, Zachary A. Kipp, Cassandra D. Gipson, Terry D. Hinds Jr.

Markey Cancer Center Faculty Publications

Steroid receptors are ligand-induced transcription factors that have broad functions among all living animal species, ranging from control of sex differences, body weight, stress responses, and many others. Their binding to coregulator proteins is regulated by corepressors and coactivators that interchange upon stimulation with a ligand. Coregulator proteins are an imperative and understudied aspect of steroid receptor signaling. Here, we discuss steroid receptor basics from protein domain structures that allow them to interact with coregulators and other proteins, their essential functions as transcription factors, and other elemental protein–protein interactions. We deliberate about the mechanisms that coregulators control in steroid receptor …

Go to article

Using Camera Stations To Investigate Occupancy Probability And Habitat Associations Of Island Spotted Skunks (Spilogale Gracilis Amphiala) On Santa Rosa And Santa Cruz Islands, Desirae Thomaier Apr 2025

Using Camera Stations To Investigate Occupancy Probability And Habitat Associations Of Island Spotted Skunks (Spilogale Gracilis Amphiala) On Santa Rosa And Santa Cruz Islands, Desirae Thomaier

Master's Theses

The California Channel Islands are unique in that two islands (Santa Rosa and Santa Cruz) support two endemic mesocarnivores, the island fox (Urocyon littoralis) and the island spotted skunk (Spilogale gracilis amphiala). Following the near-extinction of island foxes in the early 2000s, island spotted skunk populations increased significantly. Now that foxes have recovered, skunk captures have precipitously declined - possibly due to interspecific competition with foxes who have a similar diet but a larger body size and wider temporal niche. It has been proposed that skunks selectively use canyon bottoms and drainages with high vegetation cover and that these areas …

Go to article

The Effects Of Acute Nutrient Intake On Raw Segmental Bioelectrical Impedance Values And Fluid Shifts In Premenopausal Women, Callie Unrein Apr 2025

The Effects Of Acute Nutrient Intake On Raw Segmental Bioelectrical Impedance Values And Fluid Shifts In Premenopausal Women, Callie Unrein

Theses and Dissertations

Background: Raw bioimpedance measures—impedance (Z), resistance (R), reactance (Xc), and phase angle (PhA)—are emerging tools to assess hydration, cellular integrity, and muscle quality. While multifrequency bioimpedance analysis (MF-BIA) can detect acute physiological shifts, its sensitivity to nutrient intake, especially across hormonal phases in women, remains underexplored. Purpose: This study investigated how essential amino acids (EAA), carbohydrates (CHO), and water (CON) influence postprandial segmental bioimpedance and fluid distribution in healthy women, and whether these responses vary by menstrual hormone phase. Methods: Twenty-two recreationally active women (18–40 years) underwent serial MF-BIA (InBody 970) assessments during high- and low-hormone phases, randomized to one …

Go to article

Newborn Screening For X-Linked Adrenoleukodystrophy: Experiences, Perspectives, And Future Directions For Genetic Counseling, Sophia Salvatore Apr 2025

Newborn Screening For X-Linked Adrenoleukodystrophy: Experiences, Perspectives, And Future Directions For Genetic Counseling, Sophia Salvatore

Theses and Dissertations

There is a notable lack of research regarding genetic counseling practices for infants with screen-positive results for X-linked adrenoleukodystrophy (X-ALD) via newborn screening (NBS). The exploratory study aimed to understand the experiences of genetic counselors providing follow-up care for these infants, assess the complexities associated with NBS for X-ALD, identify potential gaps in genetic counseling practices, and describe the subsequent impact on patient care. A mixed-methods approach was utilized, incorporating an initial survey and optional semi-structured interviews with practicing genetic counselors who had seen a minimum of five cases of infants with screen-positive results for X-ALD in the last two …

Go to article

Genetics Education Booklets Designed For Individuals With Intellectual Disability: Perspectives From Adults With Intellectual Disability And Genetic Counselors, Audrey Hyun Sook Parrott Apr 2025

Genetics Education Booklets Designed For Individuals With Intellectual Disability: Perspectives From Adults With Intellectual Disability And Genetic Counselors, Audrey Hyun Sook Parrott

Theses and Dissertations

Visual aid tools have been consistently suggested across literature aimed at identifying methods of improving health and genetics services for individuals with intellectual disability (ID). Aids written in plain language are suggested most often. The study intends to gain perspectives from adults with ID (AWID) and genetic counselors (GCs) on Easy Read genetics educational booklets designed for individuals with mild ID. We anticipate that GCs will find the booklets to be useful and accurate, and that AWID will find the booklets to be helpful to their understanding and comprehensible. The AWID were assessed via a self-reported survey, cognitively adapted for …

Go to article

An Exploratory Study Of Disclosure Of X-Linked Conditions Between Mothers And Daughters, Madge Isabella Stuhlreyer Apr 2025

An Exploratory Study Of Disclosure Of X-Linked Conditions Between Mothers And Daughters, Madge Isabella Stuhlreyer

Theses and Dissertations

Carriers of X-linked conditions, both asymptomatic and symptomatic, face unique challenges regarding their experiences navigating the healthcare system and understanding implications of their carrier status. Studies show that mothers are known to be the main communicators of genetic information within their families, but in families affected with X-linked conditions, communication between mothers and daughters are hindered by factors such as lack of knowledge about the condition and reproductive implications, lack of emotional support, anxiety, and uncertainty about how to initiate these conversations. The purpose of this study was to explore the motivations behind mothers' decisions to initiate conversations with their …

Go to article

Investigation Of The Hdl Molecular Architecture Before And After Exercise Training., Prasun Kumar Dev Apr 2025

Investigation Of The Hdl Molecular Architecture Before And After Exercise Training., Prasun Kumar Dev

Theses and Dissertations

The functional characteristics of high-density lipoprotein (HDL) particles are influenced by their structure, including their molecular composition (e.g. HDL lipidome and proteome). However, the effects of exercise training on HDL molecular composition and its relationship with HDL-related traits are largely unknown. In this ancillary study, we investigated the HDL lipidome and proteome of 154 adults before and after 20 weeks of exercise training in the HERITAGE Family Study. The HDL-sized plasma fraction was isolated utilizing FPLC-SEC, followed by untargeted lipidomic and proteomic analysis using LC/MS. We identified 341 known lipid species while 409 HDL associated proteins. Clinical and functional related …

Go to article

Barriers In Receiving A Diagnosis Of Sanfilippo Syndrome: Perceptions From Healthcare Providers And Caregivers, Cassidy Lena Apr 2025

Barriers In Receiving A Diagnosis Of Sanfilippo Syndrome: Perceptions From Healthcare Providers And Caregivers, Cassidy Lena

Theses and Dissertations

Sanfilippo syndrome (MPS III) is a rare, degenerative condition characterized by symptoms impacting neurological functioning, behavior, and quality of life. Diagnosis is often not made until three to six years of age, but comprehensive and effective symptom management have been reported to optimize patient longevity. The aim of this study was to identify barriers to diagnosis and the corresponding impact on patients. This study surveyed healthcare providers and caregivers of individuals with Sanfilippo syndrome. Both quantitative and qualitative methods were employed to assess provider knowledge and comfortability in managing Sanfilippo syndrome. Additionally, it explored caregiver perspectives on healthcare system navigation, …

Go to article

The Association Between Parent’S Mobile Device Use And Physical Activity, Sydney Hill Apr 2025

The Association Between Parent’S Mobile Device Use And Physical Activity, Sydney Hill

Theses and Dissertations

Background. The rapid increase in mobile technology has allowed smartphones to be used almost anywhere, but a potential disadvantage of these mobile devices is the displacement of physical activity. Parents of young children are already struggling to reach higher intensities of physical activity and mobile devices might make this worse. However, most existing research on similar topics look at adults without children or uses subjective measures only. Therefore, this study aims to (1) quantify objective mobile device use from a sample of parents with preschool age children; (2) describe the duration and intensity of parents’ physical activity and inactive behavior; …

Go to article

Adipocyte-Derived Cchamide-1, Eiger, Growth-Blocking Peptide 3, And Unpaired 2 Regulate Drosophila Melanogaster Oogenesis, Chad Simmons, Isaiah H. Williams, Tancia W. Bradshaw, Alissa R. Armstrong Apr 2025

Adipocyte-Derived Cchamide-1, Eiger, Growth-Blocking Peptide 3, And Unpaired 2 Regulate Drosophila Melanogaster Oogenesis, Chad Simmons, Isaiah H. Williams, Tancia W. Bradshaw, Alissa R. Armstrong

Faculty Publications

In addition to energy storage, adipose tissue communication to other organs plays a key role in regulating organismal physiology. While the link between adipose tissue dysfunction and pathophysiology, including diabetes, chronic inflammation, and infertility, is clear, the molecular mechanisms that underlie these associations have not been fully described. We use Drosophila melanogaster as a model to better understand how adipose tissue communicates to the ovary. In this study, we utilized D. melanogaster’s robust genetic toolkit to examine the role of five adipokines known to control larval growth during development, CCHamide-1, CCHamide-2, eiger, Growth-blocking peptide 3, and unpaired 2 in regulating …

Go to article

Differential Impacts On Proteoglycan Expression In The Response To Lens Wounding In Reparative And Pro-Fibrotic Microenvironments, Janice L Walker, A. Sue Menko Apr 2025

Differential Impacts On Proteoglycan Expression In The Response To Lens Wounding In Reparative And Pro-Fibrotic Microenvironments, Janice L Walker, A. Sue Menko

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Ex vivo lens epithelial explant cultures created through a technique that mimics cataract surgery provided an ideal model with which to compare the impacts on proteoglycan expression in the response to wounding in both reparative promoting and pro-fibrotic microenvironments. On their native basement membrane capsule the injured lens epithelium undergoes regenerative repair, with the wound closing within a few days. Their migration across the wound area is led by a population of activated lens resident immune cells. The same leader cell population also directs the wounded epithelium to migrate off the outside edges of the lens explant across the surrounding …

Go to article

Nitrogen Processes Within Tropical Mangroves In Australia, M. F. Adame, N. Iram, J. N. Gamboa-Cutz, P. Masque Apr 2025

Nitrogen Processes Within Tropical Mangroves In Australia, M. F. Adame, N. Iram, J. N. Gamboa-Cutz, P. Masque

Research outputs 2022 to 2026

Coastal wetlands have long been identified as ecosystems that can ameliorate N inputs into the ocean. The processes associated with N uptake, transformation, and losses are relatively well understood for temperate wetlands; however, information on tropical wetlands is scarce. In this study, we conducted a whole ecosystem approach to measure N processes within tropical mangroves in the Moresby estuary in northeast Australia. We measured N stocks (trees and soils), inputs from sedimentation, fixation, and accumulation as woody biomass, and outputs through denitrification, anammox, and soil respiration (N2O emissions). Potential denitrification was detected along anammox (average, min-max) at 883 (485–1,450) gN …

Go to article

Kinematic Analysis Of Defensive Forms And Simple Riposte In Foil Fencing And Their Relationship To Target Accuracy, Hashem Adnan Alkilani Dr, Leena Adnan Husain Dr Apr 2025

Kinematic Analysis Of Defensive Forms And Simple Riposte In Foil Fencing And Their Relationship To Target Accuracy, Hashem Adnan Alkilani Dr, Leena Adnan Husain Dr

Journal Articles

This study analyzed kinematic variables of defensive forms and simple riposte in foil fencing and their impact on target accuracy. Eight Jordanian national team fencers (four males, four females, mean age 16.87 ± 2.53 years) participated. Motion analysis was conducted using Contemplas software and Vicon Motus 10 software, with fencing touches recorded electronically. Descriptive statistics, Spearman’s correlation, and repeated measures ANOVA were applied. Results showed the fastest defensive reaction was diagonal defense (0.30s), while horizontal defense achieved the quickest successful touch (0.30s). Increased wrist velocity in the simple riposte after semi-circular defense improved accuracy. The study recommends competition-based training, sensory-cognitive …

Go to article

Tracking Phenological Shifts Of Black Guillemots Cepphus Grylle In The Gulf Of Maine, Jocelyn L. Little Apr 2025

Tracking Phenological Shifts Of Black Guillemots Cepphus Grylle In The Gulf Of Maine, Jocelyn L. Little

Student Publications

Rapid warming in the Gulf of Maine has coincided with changes in phenology across trophic levels. Phenological change has yet to be studied in black guillemots (Cepphus grylle), a widely distributed benthic forager that is showing population decline in the region. Because black guillemots nest in burrows, their phenology can be challenging to study. I developed methods to track black guillemot phenology on Petit Manan Island, a seabird breeding colony in the Gulf of Maine. Specifically, I asked Q1) Can daily tower count data be used to predict black guillemot breeding phenology? Q2) How is black guillemot breeding phenology shifting …

Go to article

Common Terns (Sterna Hirundo) As Bioindicators For Atlantic Herring (Clupea Harengus) Distribution In The Gulf Of Maine, Logan R. Becker Apr 2025

Common Terns (Sterna Hirundo) As Bioindicators For Atlantic Herring (Clupea Harengus) Distribution In The Gulf Of Maine, Logan R. Becker

Student Publications

Effective fisheries management is increasingly challenged by climate-driven shifts in species distribution and by a lack of data on early life stages of key forage fish species. In the Gulf of Maine, Atlantic herring (Clupea harengus), a once economically dominant fishery species and a key prey species for many dependent predators, has declined due to poor early-stage recruitment and warming waters. Despite this decline, current trawl surveys do not inform early-stage Atlantic herring distribution due to mesh size limitations, leaving critical gaps in our knowledge. To address this knowledge gap, I used common terns (Sterna hirundo) …

Go to article

Diverse Microbial Prey In The Guts Of Gelatinous Grazers Revealed By Microscopy, Terra C. Hiebert, Anne W. Thompson, Kelly R. Sutherland Apr 2025

Diverse Microbial Prey In The Guts Of Gelatinous Grazers Revealed By Microscopy, Terra C. Hiebert, Anne W. Thompson, Kelly R. Sutherland

Biology Faculty Publications and Presentations

Mucous mesh grazers including pelagic tunicates and thecosome pteropods play a key role in oceanic food webs. They are taxonomically and morphologically diverse and can be highly abundant. Using their fine mucous meshes, these pelagic grazers ingest a wide range of plankton prey and link pelagic and benthic marine ecosystems. Characterizing the diet of this group is central to fully understanding marine food webs and developing accurate food web models. However, gelatinous grazers are challenging to study owing to their physically delicate composition so studying their feeding ecology requires numerous complementary techniques. Microscopy has largely been supplanted by other methods, …

Go to article

Growing South Dakota (Spring 2025), College Of Agriculture, Food And Environmental Sciences Apr 2025

Growing South Dakota (Spring 2025), College Of Agriculture, Food And Environmental Sciences

Growing South Dakota (Publication of the College of Agriculture, Food and Environmental Sciences)

[Page] 2 Keeping South Dakota's food supply safe
[Page] 6 Controlling environmental listeria
[Page] 8 Inaugural 2+2 vet program class graduates
[Page] 10 Faculty honored for excellence
[Page] 12 New leader for agronomy, horticulture, plant science
[Page] 14 Students spend spring break in South Africa
[Page] 16 Hadacek offers advice to fellow graduates
[Page] 17 Park Interpretation and Management Club starts
[Page] 18 On the front lines with invasive species
[Page] 22 Director Karla Trautman retires
[Page] 24 Helping navigate precision ag
[Page] 26 Growing bigger, better beef
[Page] 28 Jackrabbits Then and Now

Go to article

Ccr7 Regulated Mechanisms That Limit The Adaptive Immune Response, Jaisel Amilcar Cervantes Apr 2025

Ccr7 Regulated Mechanisms That Limit The Adaptive Immune Response, Jaisel Amilcar Cervantes

Open Access Theses & Dissertations

C-C chemokine receptor 7 (CCR7) is critical in guiding T cell migration within the thymus and peripheral lymphoid tissues, shaping the adaptive immune response by promoting central tolerance and regulating immune homeostasis. Although its role in lymphocyte trafficking is well established, the molecular mechanisms by which CCR7 influences thymocyte development and T cell receptor (TCR) repertoire formation remain less understood. This study examines how CCR7 deficiency impacts thymic selection, TCR diversity, and the signaling events that shape repertoire restriction. Using a homozygously deleted CCR7 murine model, we found that the absence of CCR7 results in a less restricted TCR repertoire …

Go to article

Exploring Biostimulant Efficacy Under Limited Fertilizer And Water In Utah's Watermelon Production, Evan Christensen, Milena Maria Tomaz De Oliveira, Prakriti Nepal, Youping Sun Apr 2025

Exploring Biostimulant Efficacy Under Limited Fertilizer And Water In Utah's Watermelon Production, Evan Christensen, Milena Maria Tomaz De Oliveira, Prakriti Nepal, Youping Sun

Plants, Soils, and Climate Faculty Publications

The western U.S. has recently experienced some of the driest conditions on record, and Utah has been in a multi-year drought (2019-2023) that affected the agricultural sector, including vegetable producers. While vegetables are not a primary agricultural crop in Utah, they are still an important part of the horticultural economy with 763 farms growing 6,138 acres. As the fourth largest acreage vegetable crop in Utah (almost 10% of the acreage) watermelon and related crops in the gourd family Cucurbitaceae (nearly 36% of total vegetable acreage) are important to vegetable growers. Watermelon is a water-intensive crop and requires an adequate supply …

Go to article

Analysis Of Mapt On Alzheimer’S Disease, Elaine Vanterpool Apr 2025

Analysis Of Mapt On Alzheimer’S Disease, Elaine Vanterpool

Student Posters

There are multiple factors that contribute to the onset of Alzheimer’s disease. These include genetic causes, environmental factors, and lifestyle choices. Microtubule-Associated Protein Tau. (MAPT) is a gene that is associated with the onset of Alzheimer’s disease. There are 2 main alleles of the APOE gene: H1 haplotype and H2 haplotype. H1 haplotype is the more common variant and is associated with an increased risk of developing tau-related neurodegenerative diseases.H2 haplotype is less common and is thought to have originated from an ancient inversion on chromosome 17q21. It may have some protective effects against certain tauopathies. The H1 haplotype is …

Go to article

Analysis Of Mutations Of Hydin Gene Associated With Hypertension, Elaine Vanterpool, Savania Simms Apr 2025

Analysis Of Mutations Of Hydin Gene Associated With Hypertension, Elaine Vanterpool, Savania Simms

Student Posters

Hypertension also called “High Blood Pressure” is a disorder caused by factors such as old age, genetics, weight, physical activeness, and diet. Today hypertension affects 1.28 billion adults aged 30–79 years worldwide (Mayo Clinic, 2024). When hypertension is in the range of 180/120 it can cause symptoms such as headache, chest pain, dizziness, blurred vision, and other symptoms . It is important to study the genes associated with this disorder because it helps to identify what genetic risk factors cause this as well as it helps develop more treatments for it. The gene HYDIN associated with hypertension has 51 variants …

Go to article

The Pharmaceutical Applications Of Poisonous Compounds Found In Datura Stramonium, Ruby M. Raffaldt Apr 2025

The Pharmaceutical Applications Of Poisonous Compounds Found In Datura Stramonium, Ruby M. Raffaldt

Senior Theses

Datura stramonium is a plant that is known for its toxicity. However, a facet of this plant’s noxious chemicals, namely its tropane alkaloids, can be used medicinally. The aim of this paper was to compile knowledge on the botanical, chemical, and medicinal properties of Datura stramonium L with a focus on atropine, scopolamine, and anisodamine; three tropane alkaloid compounds with the ability to be both a poison and a medicine. Information was compiled using pre-existing studies, articles, and literature reviews on D. stramonium. For each of the three alkaloids, their biosynthetic pathways, targets, administration, distribution, metabolism, and excretion were discussed. …

Go to article

Silver Nanoparticles And Vanillin Can Inhibit Collagenase Activities Of Serratia Marcescens, Elaine Vanterpool, Mya St. Louis, Josel Bryant, Kennedi Ewan, Taylor Hall, Leah Marcelle, Mayah Seal Apr 2025

Silver Nanoparticles And Vanillin Can Inhibit Collagenase Activities Of Serratia Marcescens, Elaine Vanterpool, Mya St. Louis, Josel Bryant, Kennedi Ewan, Taylor Hall, Leah Marcelle, Mayah Seal

Student Posters

Serratia marcescens is a gram-negative, disease-causing agent that belongs to the Enterobacteriaceae family. This rod-shaped microbe causes many infectious diseases such as urinary and respiratory infections, wound infections, and peritonitis, which can result in fatal bacteremia. Collagenase is an enzyme that breaks down collagen, while also playing a key role in the extracellular matrix. Collagenase uses zinc to operate that helps it break down the peptide bonds in collagen. Testing Agents ❖ Metronidazole is an antimicrobial drug used to treat infections caused by different anaerobic bacteria, such as infections in the blood, liver, bones, joints, and meninges. ❖ Vanillin is …

Go to article

Silver Nanoparticles And Natural Compounds Can Modulate Proteolytic Activities Of Escherichia Coli, Elaine Vanterpool, Simone Chotan, Wendolyn Johnson, Emilee Duany, Antonio Ward Apr 2025

Silver Nanoparticles And Natural Compounds Can Modulate Proteolytic Activities Of Escherichia Coli, Elaine Vanterpool, Simone Chotan, Wendolyn Johnson, Emilee Duany, Antonio Ward

Student Posters

Investigating the impact of antibacterial agents on Escherichia coli (E. coli) protease activity is vital for advancing new approaches to combat bacterial infections. Proteases are crucial enzymes in bacterial physiology that contribute to immune system evasion, biofilm development, and host tissue degradation. Due to these enzymes being directly involved in E. coli virulence, understanding how antibacterial compounds affect protease function may lead to innovative treatment strategies. E. coli is a gram-negative, facultatively anaerobic bacterium that exists both as a harmless intestinal commensal and a significant human pathogen. Many lives have been negatively affected by severe E. coli infections in the …

Go to article

Analyzing The Inhibition Of Chemical Compounds On Protease In P. Aeruginosa, Elaine Vanterpool, Micah Andrews, Marielle Cooper, Mitspah Eshette, Anaya Moodie-Lee, Jayda Russell, Jordon Vanterpool Apr 2025

Analyzing The Inhibition Of Chemical Compounds On Protease In P. Aeruginosa, Elaine Vanterpool, Micah Andrews, Marielle Cooper, Mitspah Eshette, Anaya Moodie-Lee, Jayda Russell, Jordon Vanterpool

Student Posters

Pseudomonas aeruginosa is a gram-negative, bacillus-shaped opportunistic pathogen, notorious for invading immunocompromised individual leading to secondary infections. These opportunistic microbes typically are implicated mild to more severe infections including burn or wound infections to more serious systemic infections. The bacterium Ps. aeruginosa utilizes a variety of virulence factors to enhance the pathogenicity of the organism. Virulence factors secreted by Ps. aeruginosa include its pili, adhesins, capsule, exotoxin A, and lipopolysaccharide (LPS). The proteases produced by Ps. aeruginosa are powerful virulence factors that can lead to tissue destruction and immune invasion. It is imperative that we find ways of regulating the …

Go to article

Improving Biocompatibility And Structural Integrity Of Decellularized Biomaterials, Elaine Vanterpool, Jayden Vanterpool, Ayanna Liburd, Andrew Mcintosh, Cayden Pyform, Cameron Scott, Jea Joseph Msie Apr 2025

Improving Biocompatibility And Structural Integrity Of Decellularized Biomaterials, Elaine Vanterpool, Jayden Vanterpool, Ayanna Liburd, Andrew Mcintosh, Cayden Pyform, Cameron Scott, Jea Joseph Msie

Student Posters

Venous grafting using synthetic and biomaterials has been one of the forefront issues of the scientific community. For years, in vitro experimentation of both bio and synthetic materials has been carried out with the hope of treating issues like chronic venous insufficiency, heart attacks, artery blockage, etc. Within these issues, there has been much success. Numerous cases have made it to clinical trials with grafts lasting as long as two years within the patient. Nonetheless, some common and persistent issues occur within all the cases observed. Despite extensive experimentation and development of the most prestigious technology, thrombosis, negative immune response, …

Go to article

Using Secreted Biomarkers In The Development Of The Detection Of Advanced Cancer Screening System, Elaine Vanterpool, Jaydan Vanterpool, Jordon Vanterpool, Robert Lister, Shania Swain, Enock Ngoga, Jovaughn Redley, Imani Shields, Dalen Jones, Santiago Moreno, Ronnie Nichalson, Jea Joseph Msie Apr 2025

Using Secreted Biomarkers In The Development Of The Detection Of Advanced Cancer Screening System, Elaine Vanterpool, Jaydan Vanterpool, Jordon Vanterpool, Robert Lister, Shania Swain, Enock Ngoga, Jovaughn Redley, Imani Shields, Dalen Jones, Santiago Moreno, Ronnie Nichalson, Jea Joseph Msie

Student Posters

As of 2020, there were an estimated 19.3 million new cancer cases and almost 10 million cancer deaths. Among the different types of cancers in the world, the most prevalent cancer, lung cancer, accounted for 23% of all cancer deaths (CDC) and has been relatively steady since 1999. However, by using Detection of Advanced Cancer Screening (D.A.C.S), many patients with cancer cases would receive efficient, reliable treatment in a timely manner. According to Cancer.gov, multiple participants reported being screened for cancer, “After they had ‘aged out of the recommended range for routine cancer screening”. (Dr. Moss) “We found that over …

Go to article

Mutations In The Pms1 Gene Associating With Ovarian Cancer, Elaine Vanterpool, Erin Hough Apr 2025

Mutations In The Pms1 Gene Associating With Ovarian Cancer, Elaine Vanterpool, Erin Hough

Student Posters

Ovarian cancer occurs when abnormal cells in the ovaries grow and divide uncontrollably, destroying healthy body tissue. Common symptoms of ovarian cancer include weight loss, fatigue, discomfort in the pelvic area, or changes in bowel habits. This study focuses on how ovarian cancer is related to the PMS1 gene. The PMS1 gene encodes MLH1, a protein involved in DNA mismatch repair (MMR) system. MMR helps connect errors that occur during DNA replication, preventing mutations and potential cancer development. When this gene is mutated, there is an increased risk of developing ovarian and other endometrial cancer. Bioinformaic softwares allow us to …

Go to article

An Evaluation Of Exercise-Related Self-Efficacy Metrics Following A Resistance Training Program In Individuals Treated For Cancer, Kayla S. Adler Apr 2025

An Evaluation Of Exercise-Related Self-Efficacy Metrics Following A Resistance Training Program In Individuals Treated For Cancer, Kayla S. Adler

Senior Theses

As the number of cancer survivors grows, managing treatment side effects and promoting healthy behaviors like physical activity is crucial. Low exercise self-efficacy, an individual's belief in their capability to perform exercise, is a significant barrier to physical activity adherence. This study assessed if an 8-week supervised resistance training program could improve self-efficacy for exercise (SEE) and outcome expectations of exercise (OEE) in individuals treated for cancer. Participants (n=25) attended twice-weekly, one-hour sessions. SEE and OEE scales were administered pre- and post-intervention. Results indicated a significant increase in SEE scores (mean difference = 8.96 ± 19.87, p = 0.041), demonstrating …

Go to article

First Prev Next Last