Valproic Acid: A Neural Outgrowth Model For The Autism Spectrum Disorder, Hannah M. Bergan

Dissertations and Theses @ UNI

Autism spectrum disorder has been dramatically on the rise since the early 1990s, with one in forty-five children being diagnosed in 2014. It is known that contributing factors to autism spectrum disorder may have genetic and epigenetic origins, as well as environmental triggers. What is still unclear, however, is the impact of teratogenic drugs, consumed by the mother, have on a developing fetus in utero. How can they lead to the child developing autistic-like behaviors? The current study documents the effects of one teratogenic drug Valproic acid, a known histone deacetylase inhibitor. It establishes the role it plays on developing …

Factors Influencing Wood Turtle (Glyptemys Insculpta) Home Range Size In Iowa: A Comparison Between Suburban And Rural Populations, Joshua Gregory Otten

Dissertations and Theses @ UNI

Home range size, movement patterns, and site fidelity of wood turtles (Glyptemys insculpta) were compared between a suburban population in Black Hawk County (BH) and a rural population in Butler County (BC), Iowa. Approximately 89% of individuals captured for studies conducted in Iowa during 2014 and 2015 were >14 years old. 45 individuals (22 females, 18 males, and 5 juveniles) were used for radio telemetry surveys in 2014–2015, 24 of which were located in BC, and 21 at BH.

Home range size of male and female wood turtles was significantly different at the 100% Minimum Convex Polygon (MCP), …

Blow Fly (Diptera: Calliphoridae) Responses To Different Colors Of Baited Traps, Oluwadamilola Olufunso Oke

Honors College Theses

Blow flies (Diptera: Calliphoridae) are usually the first insects to colonize human remains. By determining the time of colonization, a postmortem interval (PMI), or “time of death”, can be estimated. To develop more accurate PMI estimates, it is important for forensic entomologists to understand the cues that Blow flies use to locate vertebrate remains. The purpose of this study was to determine whether Blow flies use visual cues, in addition to olfactory cues, to locate carrion. Two colors of fly traps, clear and green, were constructed and chicken gizzard used as bait. Three Blow fly species exhibited a significant preference …

Testing The Optomotor Response In Sepia Bandensis, Lauren E. Thompson

Honors College Theses

Cephalopods (octopus, squid, and cuttlefish) have commonly been used as models to test visual function and camouflage due to their similarity in eye morphology with humans and because of their readily observable changes in body color in response to visual stimuli. Most studies have used a single species, Sepia officinalis, to make broad conclusions about camouflage and vision. However, these generalizations may not be applicable to all species. Here, I have examined visual function of the dwarf cuttlefish (Sepia bandensis), which differs from S. officinalis in habitat, geographic range, and size. Using the optomotor response, I quantified …

Determining The Reproductive Patterns Of The Titan Acorn Barnacle (Megabalanus Coccopoma) In Its Introduced Range, Isabel L. Moran Ms.

Honors College Theses

Invasive species are a significant conservation concern given their contribution to native species decline. The barnacle, Megabalanus coccopoma, is a common invasive species in tropical and subtropical regions of both the Pacific and Atlantic oceans. Little is known about the life history and ecology of M. coccopoma, and data on reproductive biology could provide valuable insight into its propensity to establish introduced populations. Most species of barnacle (including M. coccopoma) are hermaphroditic, but self-fertilization is rare in species studied to date. A recent genetic study of introduced M. coccopoma populations in the southeastern US showed high levels of …

Inquiry-Based Laboratory Experiences Using Ecosystem Microcosms, Roger Sauterer

Research, Publications & Creative Work

Self-sustaining ecosystem microcosms, called ecosystem jars, can easily be collected from local ponds, streams, or lakes. Sealed and exposed to sunlight, these miniature ecosystems can sustain themselves for a decade or more. Unlike Winogradsky columns, ecosystem jars are optimized for protist, animal, and plant observations and experiments, and are not altered by addition of sulfur, carbon, or cellulose sources, more accurately representing natural ecosystems. Ecosystem jars can support a variety of inquiry-based experiments, including student-designed projects, from middle school to college levels. Students, with instructor assistance, formulate hypotheses, design experiments, observe and catalog organisms by microscopy, then record their data …

Reliability Of Doming And Toe Flexion Testing To Quantify Foot Muscle Strength, Sarah T. Ridge, J. William Myrer, Mark T. Olsen, Kevin Jurgensmeier, A. Wayne Johnson

Faculty Publications

Quantifying the strength of the intrinsic foot muscles has been a challenge for clinicians and researchers. The reliable measurement of this strength is important in order to assess weakness, which may contribute to a variety of functional issues in the foot and lower leg, including plantar fasciitis and hallux valgus. This study reports 3 novel methods for measuring foot strength – doming (previously unmeasured), hallux flexion, and flexion of the lesser toes.

Modeling Beta-Traces For Beta-Barrels From Cryo-Em Density Maps, Dong Si, Jing He

Computer Science Faculty Publications

Cryo-electron microscopy (cryo-EM) has produced density maps of various resolutions. Although ά-helices can be detected from density maps at 5-8 angstrom resolutions, β-strands are challenging to detect at such density maps due to close-spacing of β-strands. The variety of shapes of β-sheets adds the complexity of β-strands detection from density maps. We propose a new approach to model traces of β-strands for β-barrel density regions that are extracted from cryo-EM density maps. In the test containing eight β-barrels extracted from experimental cryo-EM density maps at 5.5 angstrom-8.25 angstrom resolution, StrandRoller detected about 74.26% of the amino acids in the β-strands …

Comparing An Atomic Model Or Structure To A Corresponding Cryo-Electron Microscopy Image At The Central Axis Of A Helix, Stephanie Zeil, Julio Kovacs, Willy Wriggers, Jing He

Computer Science Faculty Publications

Three-dimensional density maps of biological specimens from cryo-electron microscopy (cryo-EM) can be interpreted in the form of atomic models that are modeled into the density, or they can be compared to known atomic structures. When the central axis of a helix is detectable in a cryo-EM density map, it is possible to quantify the agreement between this central axis and a central axis calculated from the atomic model or structure. We propose a novel arc-length association method to compare the two axes reliably. This method was applied to 79 helices in simulated density maps and six case studies using cryo-EM …

Getting To Know Your Yield Response Better Through Whole-Field Randomized Experiments, Taro Mieno, David Bullock

Cornhusker Economics

Six researchers at the University of Nebraska- Lincoln are working on the USDA-NIFA-funded Data Intensive Farm Management (DIFM) project. DIFM is based at the University of Illinois, and also involves the Universities of Kentucky, Massachusetts, Maryland, and Illinois State. The overarching goal of the project is to collect production data after conducting large-scale, on-farm randomized input use field trials, and then using the information to inform growers of optimal input use practices to enhance their profits. DIFM researchers hope to find a win-win situation in which more efficient crop nutrient management both increases farm profits and water quality in the …

Evaluación Del Impacto De La Desnutrición Por Exceso E Interacción Social En Escolares Del Segundo Ciclo Del Nivel Básico, Ysabel Noemí Tejeda Díaz

Theses and Dissertations

Esta investigación consistió en la evaluación del impacto de la desnutrición por exceso e interacción social en los escolares del segundo ciclo del nivel básico en una escuela pública en Santo Domingo, Republica Dominicana. Se estudiaron (a) los tipos de interacciones que se producen entre los participantes y (b) las interrelaciones sociales desarrolladas en el entorno escolar. Así como el impacto en los niveles de popularidad e influencia de acuerdo a las teorías de Herrera (2008) y Rizo (2007) en el ámbito escolar.

Se realizó una investigación mixta, a partir del abordaje del problema desde los aspectos cualitativo y cuantitativo, …

The Science Behind Popcorn, Tori R. Witruck

Natural Sciences Student Research Presentations

This poster for the Natural Sciences Poster Session at Parkland College explores the science behind popcorn, including the effects that heat and pressure put on the chemical makeup of the pericarp, endosperm and the germ of the kernel and why there are always unpopped kernels at the bottom of the bowl.

Short Term Effects On Symptoms Of Atopic Dermatitis In Children By Weather And Polution, Paolo Kinsella

Natural Sciences Student Research Presentations

This slide presentation for the Natural Sciences Poster Session at Parkland College summarizes a Korean study (Kim et al) on the effects of weather and air pollution on the severity and persistence of atopic dermatitis, a prevalent condition in Korea.

Assisted Suicide, Valerie Ontiveros

Nebraska College Preparatory Academy: Senior Capstone Projects

Assisted suicide is when a physician helps a terminally ill patient die without pain. As of right now, it is illegal in most states. Organizations about this issue were organized in the late 1930's (Humphry). According to Pro-Con. Org, 79% of patients requested assisted suicide even before they came terminally ill –if it got to that point.

Many states have different laws on assisted suicide. In no doubt, these patients go through a tremendous amount of pain and no one but themselves should decide when enough is enough. Technological advances have allowed this generation to help aid a person when …

Severe Drought Impacts Female Pheasant Physiology In Southwest Nebraska, Jessica A. Laskowski, Gwendolyn C. Bachman, Joseph J. Fontaine

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

In 2012, Nebraska experienced one of the worst droughts since the 1930s, accompanied by abnormally high temperatures. We studied the impacts of the 2012 summer drought on female ring-necked pheasant (Phasianus colchicus) body condition and baseline and stress-induced corticosterone concentrations (CORT). We hypothesized that drought conditions would reduce pheasant body condition, increase chronic stress resulting in elevated baseline CORT levels, and down-regulate pheasant stress response to acute stressors, resulting in reduced stress-induced CORT concentrations. In southwestern Nebraska, we captured female pheasants in 2012 (pre-drought) and 2013 (post-drought). Pheasants had poorer body condition after the drought. Although female CORT …

Frobenius Betti Numbers And Modules Of Finite Protective Dimension, Alessandro De Stefani, Craig Huneke, Luis Nunez-Betancourt

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

Let (R,m,K) be a local ring, and let M be an R-module of finite length. We study asymptotic invariants, bfi (M,R), defined by twisting with Frobenius the free resolution of M. This family of invariants includes the Hilbert-Kunz multiplicity (eHK (m,R) = BF0 (K,R)). We discuss several properties of these numbers that resemble the behavior of the Hilbert-Kunz multiplicity. Furthermore, we study when the vanishing of BFI (M,R,) implies that M complete characterization of the vanishing of BFi (M,R0 for one-dimensional rings. As a consequence of our methods we give conditions for the non-existence of syzygies of finite length.

Balancing Stability And Flexibility In Adaptive Governance: An Analysis Of Tools Available In U.S. Environmental Law, Robin Kundis Craig, Ahjond S. Garmestani, Craig R. Allen, Craig Anthony (Tony) Arnold, Hannah E. Birge, Daniel A. Decaro, Alexander K. Fremier, Hannah Gosnell, Edella Schlager

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

Adaptive governance must work “on the ground,” that is, it must operate through structures and procedures that the people it governs perceive to be legitimate and fair, as well as incorporating processes and substantive goals that are effective in allowing social-ecological systems (SESs) to adapt to climate change and other impacts. To address the continuing and accelerating alterations that climate change is bringing to SESs, adaptive governance generally will require more flexibility than prior governance institutions have often allowed. However, to function as good governance, adaptive governance must pay real attention to the problem of how to balance this increased …

Capturing Change: The Duality Of Time-Lapse Imagery To Acquire Data And Depict Ecological Dynamics, Emma Brinley Buckley, Craig R. Allen, Michael L. Forsberg, Michael Farrell, Andrew J. Caven

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

We investigate the scientific and communicative value of time-lapse imagery by exploring applications for data collection and visualization. Time-lapse imagery has a myriad of possible applications to study and depict ecosystems and can operate at unique temporal and spatial scales to bridge the gap between large-scale satellite imagery projects and observational field research. Time-lapse data sequences, linking time-lapse imagery with data visualization, have the ability to make data come alive for a wider audience by connecting abstract numbers to images that root data in time and place. Utilizing imagery from the Platte Basin Timelapse Project, water inundation and vegetation phenology …

Adaptive Management Of Rangeland Systems, Craig R. Allen, David G. Angeler, Joseph J. Fontaine, Ahjond S. Garmestani, Noelle M. Chaine, Kevin L. Pope, Dirac L. Twidwell Jr.

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

Adaptive management is an approach to natural resource management that uses structured learning to reduce uncertainties for the improvement of management over time. The origins of adaptive management are linked to ideas of resilience theory and complex systems. Rangeland management is particularly well suited for the application of adaptive management, having sufficient controllability and reducible uncertainties. Adaptive management applies the tools of structured decision making and requires monitoring, evaluation, and adjustment of management. Adaptive governance, involving sharing of power and knowledge among relevant stakeholders, is often required to address conflict situations. Natural resource laws and regulations can present a barrier …

Network Analysis Of A Regional Fishery: Implications For Management Of Natural Resources, And Recruitment And Retention Of Anglers, Dustin R. Martin, Daizaburo Shizuka, Christopher J. Chizinski, Kevin L. Pope

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

Angler groups and water-body types interact to create a complex social-ecological system. Network analysis could inform detailed mechanistic models on, and provide managers better information about, basic patterns of fishing activity. Differences in behavior and reservoir selection among angler groups in a regional fishery, the Salt Valley fishery in southeastern Nebraska, USA, were assessed using a combination of cluster and network analyses. The four angler groups assessed ranged from less active, unskilled anglers (group One) to highly active, very skilled anglers (group Four). Reservoir use patterns and the resulting network communities of these four angler groups differed; the number of …

Shorebird Stopover Habitat Decisions In A Changing Landscape, Caitlyn Gillespie, Joseph J. Fontaine

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

To examine how habitat use by sandpipers (Calidris spp.; Baird’s sandpipers, dunlin, least sandpipers, pectoral sandpipers, semipalmated sandpipers, stilt sandpipers, and white-rumped sandpipers) varies across a broad suite of environmental conditions, we conducted surveys at wetlands throughout the spring migratory period in 2013 and 2014 in 2 important stopover regions: the Rainwater Basin (RWB) in Nebraska, USA, and the Prairie Pothole Region (PPR) in South Dakota, USA. Because providing adequate energetic resources for migratory birds is a high priority for wetland management, we also measured invertebrate abundance at managed wetlands in the RWB to determine how food abundance influences …

Species Distributions Models In Wildlife Planning: Agricultural Policy And Wildlife Management In The Great Plains, Joseph J. Fontaine, Christopher F. Jorgensen, Erica F. Stuber, Lutz F. Gruber, Andrew A. Bishop, Jeffrey J. Lusk, Eric S. Zach, Karie L. Decker

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

We know economic and social policy has implications for ecosystems at large, but the consequences for a given geographic area or specific wildlife population are more difficult to conceptualize and communicate. Species distribution models, which extrapolate species-habitat relationships across ecological scales, are capable of predicting population changes in distribution and abundance in response to management and policy, and thus, are an ideal means for facilitating proactive management within a larger policy framework. To illustrate the capabilities of species distribution modeling in scenario planning for wildlife populations, we projected an existing distribution model for ring-necked pheasants (Phasianus colchicus) onto …

Protected Areas As Social-Ecological Systems: Perspectives From Resilience And Social-Ecological Systems Theory, Graeme S. Cumming, Craig R. Allen

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

Conservation biology and applied ecology increasingly recognize that natural resource management is both an outcome and a driver of social, economic, and ecological dynamics. Protected areas offer a fundamental approach to conserving ecosystems, but they are also social-ecological systems whose ecological management and sustainability are heavily influenced by people. This editorial, and the papers in the invited feature that it introduces, discuss three emerging themes in social-ecological systems approaches to understanding protected areas: (1) the resilience and sustainability of protected areas, including analyses of their internal dynamics, their effectiveness, and the resilience of the landscapes within which they occur; (2) …

A Bayesian Method For Assessing Multi-Scale Species-Habitat Relationships, Erica F. Stuber, Lutz F. Gruber, Joseph J. Fontaine

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

Context Scientists face several theoretical and methodological challenges in appropriately describing fundamental wildlife-habitat relationships in models. The spatial scales of habitat relationships are often unknown, and are expected to follow a multi-scale hierarchy. Typical frequentist or information theoretic approaches often suffer under collinearity in multiscale studies, fail to converge when models are complex or represent an intractable computational burden when candidate model sets are large.

Objectives Our objective was to implement an automated, Bayesian method for inference on the spatial scales of habitat variables that best predict animal abundance.

Methods We introduce Bayesian latent indicator scale selection (BLISS), a Bayesian …

Reframing Communication About Zika And Mosquitoes To Increase Disease Prevention Behavior, Amanda E. Sorensen, Rebecca C. Jordan, Shannon Ladeau

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

Emergence of invasive vector species and the diseases they carry present a clear danger to the public as well as a challenge for scientists and experts to control effectively. Given the urgent need to address this phenomenon, we suggest that desired public action toward these invasive vectors can be motivated through intentional framing in science communication. In this paper, we sought to evaluate the effect of framing about ZIKV (Zika virus) on reported willingness to comply with mosquito prevention action. Post framing intervention, we found a significant increase (N = 26, p < 0.001) in individuals willing to take preventative action against mosquitoes. By methodically investigating best communication practices, this study and others can help practitioners mobilize communities to address large-scale ecological problems. Additionally, the principles outlined here may be transferrable to other communication efforts about ecological issues outside of ZIKV and mosquitoes.

The Nebraska Stream Fishery Surveys: Being A Comparison Of The First Statewide Collections Of Raymond Johnson (1939-1941) With A Recent Resurvey (2003-2005), Steven C. Schainost, Edward J. Peters

Nebraska Game and Parks Commission: White Papers, Conference Presentations, and Manuscripts

The first statewide survey of Nebraska fishes was done between 1939 and 1941. This survey was repeated between 2003 and 2005. This document compares and contrasts the results of those two surveys to illustrate what has changed and what hasn't changed over that 60 year period. It is hoped that this document can serve as a resource for future researchers to track changes in Nebraska's fish communities.

Five Species Of Fossil Equids Preserved In-Situ At Ashfall Fossil Beds, Rick E. Otto

University of Nebraska State Museum: Programs Information

Fully articulated, three-dimensionally preserved skeletons from five species of fossil Equids are now represented, and preserved in-situat the Ashfall Fossil Beds in northcentral Nebraska. The site is well known for dozens of barrel-bodied rhino (Teleoceras major) skeletons. A diversity of horse species that inhabited Nebraska during the late Miocene Epoch have been exposed in the fossil bed. Genera include Cormohipparion, Neohipparon, Pliohippus, Protohippus, and Pseudhipparion. An exceptionally well-preserved skeleton of the small-sized, three-toed species Pseudhipparion gratumwas recently exposed, and is on display only a few feet from where visitors stand.

Climate Science Special Report: Fourth National Climate Assessment (Nca4), Volume I

National Oceanographic and Atmospheric Administration: Technical Reports and Related Materials

This report is an authoritative assessment of the science of climate change, with a focus on the United States. It represents the first of two volumes of the Fourth National Climate Assessment, mandated by the Global Change Research Act of 1990.

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Writing Team

Coordinating Lead Authors

• Donald J. Wuebbles National Science Foundation and U.S. Global Change Research Program – University of Illinois
• David W. Fahey NOAA Earth System Research Lab
• Kathy A. Hibbard NASA Headquarters

Lead Authors …

Detoxification Of Mitochondrial Oxidants And Apoptotic Signaling Are Facilitated By Thioredoxin-2 And Peroxiredoxin-3 During Hyperoxic Injury, Benjamin J. Forred, Darwin R. Daugaard, Brianna K. Titus, Ryan R. Wood, Miranda J. Floen, Michelle L. Booze, Peter F. Vitiello

School of Veterinary and Biomedical Sciences: Faculty Publications

Mitochondria play a fundamental role in the regulation of cell death during accumulation of oxidants. High concentrations of atmospheric oxygen (hyperoxia), used clinically to treat tissue hypoxia in premature newborns, is known to elicit oxidative stress and mitochondrial injury to pulmonary epithelial cells. A consequence of oxidative stress in mitochondria is the accumulation of peroxides which are detoxified by the dedicated mitochondrial thioredoxin system. This system is comprised of the oxidoreductase activities of peroxiredoxin-3 (Prx3), thioredoxin-2 (Trx2), and thioredoxin reductase-2 (TrxR2). The goal of this study was to understand the role of the mitochondrial thioredoxin system and mitochondrial injuries during …

Maternal Inflammation At Mid-Gestation In Pregnant Rats Impairs Fetal Muscle Growth And Development At Term, C. N. Cadaret, K. A. Beede, E. M. Merrick, T. L. Barnes, J. D. Loy, D. T. Yates

School of Veterinary and Biomedical Sciences: Faculty Publications

Intrauterine growth restriction (IUGR) is a leading cause of perinatal morbidity and mortality. Low birth weight resulting from preterm birth and/or IUGR is an underlying factor in 60–80% of perinatal death worldwide, and is particularly common in developing countries (UNICEF, 2008). Furthermore, studies have linked IUGR and the associated fetal malnutrition to increased incidence of metabolic syndrome in adult life (Barker et al., 1993; Godfrey and Barker, 2000). The “thrifty phenotype hypothesis” developed by David Barker (Hales et al., 1991) states that IUGR-associated fetal malnutrition forces the fetus to spare nutrients by altering tissue-specific metabolism in order to survive. In …