Life Sciences Commons^™

Kentucky Warbler (Vol. 93, No. 1), Kentucky Library Research Collections

The Kentucky Warbler

No abstract provided.

Nebline, February 2017

NEBLINE Newsletter Archive from Nebraska Extension in Lancaster County

Feature: 3rd Graders Learn About Life Cycle By Hatching Eggs in Classrooms

Food & Health

Farm & Acreage

Pests & Wildlife

Horticulture

Early Childhood

4-H & Youth

and other extension news and events

Mitochondria Mediate Cell Membrane Repair And Contribute To Duchenne Muscular Dystrophy., Maria C Vila, Sree Rayavarapu, Marshall W Hogarth, Jack H Van Der Meulen, Adam Horn, Aurelia Defour, Shin'ichi Takeda, Kristy J. Brown, Yetrib Hathout, Kanneboyina Nagaraju, Jyoti K. Jaiswal

Genomics and Precision Medicine Faculty Publications

Dystrophin deficiency is the genetic basis for Duchenne muscular dystrophy (DMD), but the cellular basis of progressive myofiber death in DMD is not fully understood. Using two dystrophin-deficient mdx mouse models, we find that the mitochondrial dysfunction is among the earliest cellular deficits of mdx muscles. Mitochondria in dystrophic myofibers also respond poorly to sarcolemmal injury. These mitochondrial deficits reduce the ability of dystrophic muscle cell membranes to repair and are associated with a compensatory increase in dysferlin-mediated membrane repair proteins. Dysferlin deficit in mdx mice further compromises myofiber cell membrane repair and enhances the muscle pathology at an asymptomatic …

Pcsk9 Genetic Variants And Risk Of Type 2 Diabetes: A Mendelian Randomisation Study, A. Schmidt, D. Swerdlow, M. Holmes, R. Patel, Z. Fairhurst-Hunter, Cara L. Carty, +Several Additional Authors

Pediatrics Faculty Publications

BACKGROUND:

Statin treatment and variants in the gene encoding HMG-CoA reductase are associated with reductions in both the concentration of LDL cholesterol and the risk of coronary heart disease, but also with modest hyperglycaemia, increased bodyweight, and modestly increased risk of type 2 diabetes, which in no way offsets their substantial benefits. We sought to investigate the associations of LDL cholesterol-lowering PCSK9 variants with type 2 diabetes and related biomarkers to gauge the likely effects of PCSK9 inhibitors on diabetes risk.

METHODS:

In this mendelian randomisation study, we used data from cohort studies, randomised controlled trials, case control studies, and …

Primary Utricle Structure Of Six Halimeda Species And Potential Relevance For Ocean Acidification Tolerance, Katherine E. Peach, Marguerite S. Koch, Patricia Blackwelder, Debbie Guerrero-Given, Naomi Kamasawa

Marine & Environmental Sciences Faculty Articles

Variations in utricle morphology may be responsible for different tolerances to ocean acidification (OA) within the macroalgal genus Halimeda, an important sediment producer on reefs. However, differences in species’ utricle morphology and their relationship to calcification and crystal formation have not been well articulated. In the present study, we characterized the utricle morphologies of six Halimeda species. Primary utricle ultrastructure was quantitatively and qualitatively compared to tissue inorganic content and crystal microstructure. Morphologies differed across species and several morphometric relationships were revealed. Primary utricle size (r²=0.70) and diffusion pathway length (r²=0.87) had inverse relationships with …

The Need For Standardized Assessment Of Muscle Quality In Skeletal Muscle Function Deficit And Other Aging-Related Muscle Dysfunctions: A Symposium Report, Rosaly Correa De Araujo, Michael O. Harris-Love, Iva Miljkovic, Maren Fragala, Brian Anthony, Todd Manini

Exercise and Nutrition Sciences Faculty Publications

A growing body of scientific literature suggests that not only changes in skeletal muscle mass, but also other factors underpinning muscle quality, play a role in the decline in skeletal muscle function and impaired mobility associated with aging. A symposium on muscle quality and the need for standardized assessment was held on April 28, 2016 at the International Conference on Frailty and Sarcopenia Research in Philadelphia, Pennsylvania. The purpose of this symposium was to provide a venue for basic science and clinical researchers and expert clinicians to discuss muscle quality in the context of skeletal muscle function deficit and other …

Eccentric Exercise Program Design: A Periodization Model For Rehabilitation Applications, Michael O. Harris-Love, Bryant Seamon, Tomas I. Gonzales, Haniel J. Hernandez, Donte Pennington, Brian Hoover

Exercise and Nutrition Sciences Faculty Publications

The applied use of eccentric muscle actions for physical rehabilitation may utilize the framework of periodization. This approach may facilitate the safe introduction of eccentric exercise and appropriate management of the workload progression. The purpose of this data-driven Hypothesis and Theory paper is to present a periodization model for isokinetic eccentric strengthening of older adults in an outpatient rehabilitation setting. Exemplar and group data are used to describe the initial eccentric exercise prescription, structured familiarization procedures, workload progression algorithm, and feasibility of the exercise regimen. Twenty-four men (61.8 ±6.3 years of age) completed a 12-week isokinetic eccentric strengthening regimen involving …

Gestational Diabetes Mellitus And The Predisposing Factors, Syeda Sadia Fatima, Rehana Rehman, Faiza Alam, Sarosh Madhani, Bushra Chaudhry, Taseer Ahmed Khan

Department of Biological & Biomedical Sciences

Objective: To evaluate the occurrence of gestational diabetes mellitus and its association with demographic and anthropometric variables in pregnant women.
Methods: This cross-sectional study was conducted at the Aga Khan University Hospital, Abbasi Shaheed Hospital and Memon Hospital in Karachi, from February 2014 to December 2015, and comprised pregnant women who were screened by 75-g 2-hour oral glucose tolerance test, (24-28 weeks of gestation) and classified as per the criteria of the International Association of Diabetes and Pregnancy Study Group. Weight, body mass index and serum glycated haemoglobin levels were measured. Women with pre-gestational diabetes were excluded. SPSS 21 was …

Hmba Is A Putative Hsp70 Activator Stimulating Hexim1 Expression That Is Down-Regulated By Estrogen, Rati Lama, Chunfang Gan, Nethrie Idippily, Viharika Bobba, David Danielpour, Monica Montano, Bin Su Ph.D.

Chemistry Faculty Publications

Hexamethylene bis-acetamide inducible protein 1 (HEXIM1) is identified as a novel inhibitor of estrogen stimulated breast cell growth, and it suppresses estrogen receptor-a transcriptional activity. HEXIM1 protein level has been found to be downregulated by estrogens. Recently, HEXIM1 has been found to inhibit androgen receptor transcriptional activity as well. Researchers have used Hexamethylene bisacetamide (HMBA) for decades to stimulate HEXIM1 expression, which also inhibit estrogen stimulated breast cancer cell gene activation and androgen stimulated prostate cancer gene activation. However, the direct molecular targets of HMBA that modulate the induction of HEXIM1 expression in mammalian cells have not been identified. Based …

Islet Adaptations In Fetal Sheep Persist Following Chronic Exposure To High Norepinephrine, Xiaochaun Chen, Amy C. Kelly, Dustin T. Yates, Antoni R. Macko, Ronald M. Lynch, Sean W. Limesand

Department of Animal Science: Faculty Publications

Complications in pregnancy elevate fetal norepinephrine (NE) concentrations. Previous studies in NE-infused sheep fetuses revealed that sustained exposure to high NE resulted in lower expression of α2-adrenergic receptors in islets and increased insulin secretion responsiveness after acutely terminating the NE infusion. In this study, we determined if the compensatory increase in insulin secretion following chronic elevation of NE is independent of hyperglycemia in sheep fetuses and whether it is persistent in conjunction with islet desensitization to NE. Following an initial assessment of glucose-stimulated insulin secretion (GSIS) at 129±1 days of gestation, fetuses were continuously infused for seven days with NE …

Utah State University Evaluation Of Ring To Green Final Research Report, Kelly Kopp, Paul Harris

CWEL Publications

Necrotic ring spot (Ophiosphaerella korrae) is the most commonly diagnosed fungal turfgrass disease by the Utah State University Plant Pest Diagnostic Laboratory. The disease effects coolseason grasses in the state and region, particularly Kentucky bluegrass. The necrotic ring spot (NRS) disease pathogen infects and kills turfgrass roots and crowns, resulting in the blighted appearance of turf amidst an otherwise healthy area of turf

In the late summer/fall of 2015, Utah State University (USU) began a research study of the Ring to GREEN product by GreenMaster Distributing, LLC for the control of necrotic ring spot in turfgrass. Prior to USU’s involvement, …

Contribution Of Pentose Catabolism To Molecular Hydrogen Formation By Targeted Disruption Of Arabinose Isomerase (Araa) In The Hyperthermophilic Bacterium Thermotoga Maritima, Derrick White, Raghuveer Singh, Deepak Rudrappa, Jackie Mateo, Levi Kramer, Laura Freese, Paul H. Blum

School of Biological Sciences: Faculty Publications

Thermotoga maritima ferments a broad range of sugars to form acetate, carbon dioxide, traces of lactate, and near theoretic yields of molecular hydrogen (H₂). In this organism, the catabolism of pentose sugars such as arabinose depends on the interaction of the pentose phosphate pathway with the Embden-Myerhoff and Entner-Doudoroff pathways. Although the values for H₂ yield have been determined using pentose-supplemented complex medium and predicted by metabolic pathway reconstruction, the actual effect of pathway elimination on hydrogen production has not been reported due to the lack of a genetic method for the creation of targeted mutations. Here, …

Replacement Of Fishmeal With Processed Meal From Knife Fish Chitala Ornata In Diets Of Juvenile Nile Tilapia Oreochromis Niloticus, Janice A. Ragaza, Sherilyn T. Abarra, Stephanie F. Velasquez, Kristina Daniela D.C. Guzman, Jaime Lorenzo F. Felipe, Melchor Tayamen

Biology Faculty Publications

A 60-day feeding trial was conducted to assess the effects of processed meal from knife fish Chitala ornata (KFM) as fishmeal replacement in diets of Nile tilapia Oreochromis niloticus juveniles. Five iso-nitrogenous (36.4% in dry matter) and isolipidic diets (8.6% in dry matter) with 0 (D1), 25 (D2), 50 (D3), 75 (D4) and 100% (D5) KFM inclusions were prepared. With a stocking density of 15 fish (0.59 ± 0.01 g) per tank, tilapia juveniles were distributed randomly in fifteen 30-L tanks. Results indicate a significant increase (P < 0.05) in the percent average weight gain, specific growth rate, and feed …

Forage News [2017-02], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

• Dr. Chris Teutsch - New Forage Extension Specialist
• Benefits of Clovers: Cattle Health and Increased Production
• Industrial Hemp - Any Potential as Forage?

A Comparison Between Wellness Awareness Among Medical Students, Rehana Rehman, Shahjahan Katpar, Mehwish Hussain, Rakhshaan Khan, Mukhtiar Baig

Department of Biological & Biomedical Sciences

Objective: To assess and compare the dimensions of spiritual wellness as elements of quality care in medical students of private and public medical universities.
Methods: The cross-sectional study was carried out at private and public medical universities in Karachi from November 2013 to January 2015.Students from both genders and all ethnic groups19-23 years of age were included. The responses of spiritual wellness were obtained and evaluated on a four-point Likert's scale; score ranging from 0-3. Data was analysed using Predictive Analysis Software version 18.
Results: Out of 736 students, 286 (38.9%) were from public medical universities and 450 (61.1%) were …

Assessment Of Childhood Domestic Injuries Among Joint And Nuclear Families Of Karachi, Asif Khaliq, Amreen Rao, Shahroz Siddiqui, Ghulam Mujtaba Nasir

Department of Biological & Biomedical Sciences

To assess the frequencies and factors of domestic injuries among children aged less than 5 years. This is a cross sectional study, in which parents who have child less than 5 years of age were targeted. A total of 246 participants had provided satisfactory information and they were approached by non-probability purposive sampling technique from January 2016 to June 2016. The data was entered in Excel and then imported to SPSS 19.0 for inferential analysis. In this study, 89.8% (n = 221) mothers and 10.2% (n = 25) father who had participated. 52.08% (n = 123) parents were from joint …

Comparison Of Two Interactive Tutorial Methods: Results From A Medical College In Karachi, Rabiya Rehan, Lubna Farooqi, Hira Khan, Rehana Rehman

Department of Biological & Biomedical Sciences

Objective: To compare perception of students on usefulness of interactive tutorials and clinically-oriented problem-solving tutorials.
Methods: The cross-sectional study was carried out from January 2012 to November 2013 at Bahria University Medical and Dental College, Karachi. The perception of medical students on usefulness of interactive tutorials and clinically-oriented problem-solving tutorials was acquired through a questionnaire distributed to medical students having completed the first two years of studies. The responses on various aspects of learning of physiology were acquired on a scale of poor, good or excellent. The learning abilities and acquired skills were compared in terms of not at all, …

Host Tissue Environment Directs Activities Of An Epichloë Endophyte, While It Induces Systemic Hormone And Defense Responses In Its Native Perennial Ryegrass Host, Jan Schmid, Robert Day, Ningxin Zhang, Pierre-Yves Dupont, Murray P. Cox, Christopher L. Schardl, Niki Minards, Neil Moore, Daniel R. Harris, Yanfei Zhou

Plant Pathology Faculty Publications

Increased resilience of pasture grasses mediated by fungal Epichloë endophytes is crucial to pastoral industries. The underlying mechanisms are only partially understood and likely involve very different activities of the endophyte in different plant tissues and responses of the plant to these. We analyzed the transcriptomes of Epichloë festucae and its host, Lolium perenne, in host tissues of different function and developmental stages. The endophyte contributed approximately 10× more to the transcriptomes than to the biomass of infected tissues. Proliferating mycelium in growing host tissues highly expressed genes involved in hyphal growth. Nonproliferating mycelium in mature plant tissues, transcriptionally …

Ergot And Loline Alkaloid Concentrations In Endophyte-Infected Tall Fescue Tillers, Rebecca L. Mcculley

Forage Climate Change Experiment Research Data

Approximately 40 tall fescue tillers were randomly collected and frozen from each of the 20 treatment plots.

Tillers were cut at 7.6 cm above ground level and tested for the presence of the Epichloe endophyte using an enzyme-linked immunosorbent assay.

Tillers from each plot were sorted into 'infected' vs 'uninfected' groups, lyophilized, and ground through a 1mm screen using a Cyclotec 1093 mill.

Ground material from the endophyte infected tillers was analyzed for ergot and loline alkaloids in the lab of Lowell Bush at the University of Kentucky, Plant and Soil Sciences Dept.

For details on alkaloid analyses see: McCulley …

Responses Of King Penguin Aptenodytes Patagonicus Adults And Chicks To Two Food-Related Odours, Gregory B. Cunningham, Sarah Leclaire, Camille Toscani, Francesco Bonadonna

Biology Faculty/Staff Publications

Increasing evidence suggests that penguins are sensitive to dimethyl sulphide (DMS), a scented airborne compound that a variety of marine animals use to find productive areas of the ocean where prey is likely to be found. Here we present data showing that king penguins Aptenodytes patagonicus are also sensitive to DMS. We deployed DMS on a lake near a king penguin colony at Ratmanoff beach in the Kerguelen archipelago. We also presented DMS to ‘sleeping’ adults on the beach. On the lake, penguins responded to the DMS deployments by swimming more, while on the beach, penguins twitched their heads and …

Bridging The Gap: Joint Fire Science Program Outcomes, Stephen W. Barrett

Joint Fire Science Program Digests

The Joint Fire Science Program (JFSP) has funded an impressive number of research projects over the years. However, the number of projects does not necessarily provide an accurate picture of the program’s effectiveness. Over the last decade, researchers have collected data and conducted several studies to determine whether the results of JFSP-funded projects are reaching potential users and informing management decisions and actions. Those studies have helped identify issues and influence changes within the program. Early studies pointed out the need for a boundary-spanning organization to improve delivery of science information, which resulted in the establishment of the Fire Science …

Do The Shuffle: Changes In Symbiodinium Consortia Throughout Juvenile Coral Development, Hannah G. Reich, Deborah L. Robertson, Gretchen Goodbody-Gringley

Biology

Previous studies of symbiotic associations between scleractinians corals and Symbiodinium have demonstrated that the consortium of symbionts can change in response to environmental conditions. However, less is known about symbiont shuffling during early coral development, particularly in brooding species. This study examined whether Symbiodinium consortia (1) varied in Porites astreoides on shallow (10m) and upper mesophotic (30m) reefs, (2) changed during coral development, and (3) influenced growth of juveniles in different environments. Symbiodinium ITS2 sequences were amplified using universal primers and analyzed using phylotype-specific primers designed for phylotypes A, B, and C. Adults from both depths were found to host …

An Assessment Of Potential False Positive E.Coli Pyroprints In The Cplop Database, Skyler A. Gordon

Master's Theses

The genetic information found in each species of organism is unique, and can be used as a tool to differentiate at the molecular level. This has caused rapid genotyping methods to become the cornerstone of a new area of research dependent on reading the genome as a form of identification. One of these specific identification methods, known as pyroprinting, relies on the small variation of DNA sequences within the same species to develop a unique, reproducible fingerprint. By simultaneously pyrosequencing multiple polymorphic loci within the ribosomal operons known as the intergenic transcribed spacers, a reproducible output is obtained, known as …

Teaching Morphological Species Identification To Forensic Science Students: Advantages, Problems And Results, Gregory Nigoghosian, Lauren Weidner, Ludmila Nunes, Trevor Stamper

IMPACT Presentations

Poster presented at the 69th American Academy of Forensic Science Annual Meeting, New Orleans, LA, USA. The poster discusses findings of a study of how students identify morphological species.

1839 - California: A History Of Upper And Lower California From Their First Discovery To The Present Time, Alexander Forbes

Miscellaneous Publications – Mexican

The first full account in English to relate exclusively to California, this book covers the history, climate, soil, natural productions, agriculture, and commerce, as well as the establishment of the missions and the conditions of the “free and domesticated” Indians. It includes an appendix on steam navigation in the Pacific.

Plant Compound Pest Control In California Strawberry (Fragaria × Ananassa) Production, Eli Mahanes Weissman

Master's Theses

Allelopathy occurs when one organism releases a compound into the environment that affects the functioning of another organism. Scientists have long suspected that alleopathic plant compounds could offer novel, softer chemistries to the ongoing battle of controlling pests in agricultural fields. Strawberry growers rely on toxic fumigants to kill soilborne fungal pests, weeds, nematodes, and insects. Increased regulations have reduced the use of fumigants (including methyl bromide), and strawberry growers need new sustainable pest control solutions. We selected four putative allelochemicals with known fungicidal and herbicidal activity (ferulic acid, gallic acid, juglone, and p-Coumaric acid). We assessed the pesticidal activity …

Seed Biology And Yield Of Grain Crops, Dennis B. Egli

Plant and Soil Sciences Faculty Book Gallery

Description from CABI (Centre for Agriculture and Biosciences International):

This new edition of an established title examines the determination of grain crop yield from a unique perspective, by concentrating on the influence of the seed itself. As the food supply for an expanding world population is based on grain crops harvested for their seeds, understanding the process of seed growth and its regulation is crucial to our efforts to increase production and meet the needs of that population. Yield of grain crops is determined by their assimilatory processes such as photosynthesis and the biosynthetic processes in the seed, which are …

Correcting The Trajectory Of Stroke Therapeutic Research, Keith R. Pennypacker, Gregory J. Bix, Justin F. Fraser

Neurology Faculty Publications

No abstract provided.

Effects Of An Amylopectin And Chromium Complex On The Anabolic Response To A Suboptimal Dose Of Whey Protein, T. N. Ziegenfuss, H. L. Lopez, A. Kedia, S. M. Habowski, J. E. Sandrock, B. Raub, Chad M. Kerksick, A. A. Ferrando

Faculty Scholarship

Background

Previous research has demonstrated the permissive effect of insulin on muscle protein kinetics, and the enhanced insulin sensitizing effect of chromium. In the presence of adequate whole protein and/or essential amino acids (EAA), insulin has a stimulatory effect on muscle protein synthesis, whereas in conditions of lower blood EAA concentrations, insulin has an inhibitory effect on protein breakdown. In this study, we determined the effect of an amylopectin/chromium (ACr) complex on changes in plasma concentrations of EAA, insulin, glucose, and the fractional rate of muscle protein synthesis (FSR).

Methods

Using a double-blind, cross-over design, ten subjects (six men, four …

Biophysical Tools To Study Cellular Mechanotransduction, Ismeel Muhamed, Farhan Chowdhury, Venkat Maruthamuthu

Mechanical & Aerospace Engineering Faculty Publications

The cell membrane is the interface that volumetrically isolates cellular components from the cell's environment. Proteins embedded within and on the membrane have varied biological functions: reception of external biochemical signals, as membrane channels, amplification and regulation of chemical signals through secondary messenger molecules, controlled exocytosis, endocytosis, phagocytosis, organized recruitment and sequestration of cytosolic complex proteins, cell division processes, organization of the cytoskeleton and more. The membrane's bioelectrical role is enabled by the physiologically controlled release and accumulation of electrochemical potential modulating molecules across the membrane through specialized ion channels (e.g., Na^⁺, Ca²⁺, K^⁺ channels). …