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Articles 1111 - 1140 of 255617
Full-Text Articles in Life Sciences
The Evaluation Of Roughages Under The Gdr Feed EvaluaTion System, Reinhard Schiemann
The Evaluation Of Roughages Under The Gdr Feed EvaluaTion System, Reinhard Schiemann
IGC Proceedings (1977-2023)
The purpose and content of the GDR Feed Evaluation System are discussed in the form of a summary report. The GDR Feed Evaluation System incorporates, in a form suitable for practical application, the following:
Parameters and methods for the complex evaluation of feeds with particular reference to energy and protein (including amino acids), prepared in the form of detailed feed tables for feeding and planning purposes [9, 10];
Parameters and methods for determining daily feed requirements and application rates, in the fonn of energy and nutrient • requirement standards for composing optimum rations according to animal species and performance (9, …
Re-Examining Endemic Smoky Dace As An Indicator Species In The Upper Little Tennessee River Index Of Biological Integrity, Tayton C. Alvis, William O. Mclarney, Radmila Petric, Jason P. Love
Re-Examining Endemic Smoky Dace As An Indicator Species In The Upper Little Tennessee River Index Of Biological Integrity, Tayton C. Alvis, William O. Mclarney, Radmila Petric, Jason P. Love
Southeastern Fishes Council Proceedings
Fish communities can be used to evaluate water quality and stream ecosystem health, helping resource managers understand the effects of anthropogenic disturbance. Fish species inform indexes of biological integrity through their ecological traits and tolerance to stressors (e.g. tolerant of disturbance, intolerant of disturbance), but these designations are difficult to determine without localized, species-specific information. The Upper Little Tennessee River watershed is subject to long-term aquatic biomonitoring, applying an index of biological integrity tailored to the region. In this index, the undescribed endemic Smoky Dace (Clinostomus sp.) is classified as intolerant based on a previous designation for the Rosyside Dace …
Phytochemical Analysis And Safety Assessment Of Watercress Nasturtium Officinale: Antioxidant Capacity, Heavy Metal Profiling, And Toxicity Using Brine Shrimp Model, Qurrota A’Yunin, Chamini Kasun Hemachandra, Muhaimin Rifa’I, Yoga Dwi Jatmiko, Maftuch Maftuch, Rizky Fadilla Agustin Rangkuti, Cucun Herlina, Zulfa Mahdiatur Rasyida, Moh Dliyauddin
Phytochemical Analysis And Safety Assessment Of Watercress Nasturtium Officinale: Antioxidant Capacity, Heavy Metal Profiling, And Toxicity Using Brine Shrimp Model, Qurrota A’Yunin, Chamini Kasun Hemachandra, Muhaimin Rifa’I, Yoga Dwi Jatmiko, Maftuch Maftuch, Rizky Fadilla Agustin Rangkuti, Cucun Herlina, Zulfa Mahdiatur Rasyida, Moh Dliyauddin
Karbala International Journal of Modern Science
Medicinal plants have attracted growing attention as sources of natural bioactive compounds for sustainable aquaculture and health. This study evaluated the phytochemical composition, antioxidant activity, heavy metal profile, and acute toxicity of watercress (Nasturtium officinale W.T. Aiton) methanol extract using maceration, qualitative and quantitative (TPC, TFC, antioxidant DPPH) phytochemical assay, XRF, and BSLA. Phytochemical screening of plant extracts showed the existence of flavonoids, alkaloids, phenols, tannins, triterpenoids, and saponins, but not steroidal. The TPC and TFC were 20.6 mg GAE/g and 10.8 mg QE/g, respectively. The extract displayed significant antioxidant activity (IC50 = 64.78 µg/mL in DPPH assay). …
Machine Learning Integrated Designing And Screening Of 8-Hydroxyquinoline Based Metallo-Beta-Lactamase Inhibitors, Anthony M. Baudino, Kari Stone
Machine Learning Integrated Designing And Screening Of 8-Hydroxyquinoline Based Metallo-Beta-Lactamase Inhibitors, Anthony M. Baudino, Kari Stone
Chemistry Department Faculty Articles
The rapid emergence of metallo-b-lactamase-mediated antibiotic resistance has created an urgent need for new inhibitor discovery strategies. In this work, a machine-learning-guided workflow was developed to generate and prioritize potential inhibitors targeting NDM-1. A SMILES-based variational autoencoder was first pretrained on a broad molecular dataset to learn general chemical syntax and latent molecular representations. The model was then fine-tuned on an 8-hydroxyquinoline-enriched dataset to bias molecular generation toward zinc-binding chemical space relevant to metallo-β-lactamase inhibition. Generated compounds were processed through structural filtering and docking-based evaluation to create training data for downstream predictive modeling. Molecular fingerprints and physicochemical descriptors were then …
Thermoclock:A Novel Automated Temperature Regulation Device That Can Model Circadian Entrainment And Disruption In 2d And 3d In Vitro Models, Kaiyin Kelly Zhang, Cathryn A. Cutia, Chanelle A. Moise, Bhavna Kalyanaraman, Kaitlyn Chhe, Jiexin Wang, Michelle E. Farkas, Ilia N. Karatsoreos, Mary Harrington, Meghan E. Huber, Cathal J. Kearney
Thermoclock:A Novel Automated Temperature Regulation Device That Can Model Circadian Entrainment And Disruption In 2d And 3d In Vitro Models, Kaiyin Kelly Zhang, Cathryn A. Cutia, Chanelle A. Moise, Bhavna Kalyanaraman, Kaitlyn Chhe, Jiexin Wang, Michelle E. Farkas, Ilia N. Karatsoreos, Mary Harrington, Meghan E. Huber, Cathal J. Kearney
Biological Sciences: Faculty Publications
Circadian rhythms are critical for maintaining homeostasis and regulating physiological functions, and consequentially impact disease progression; yet, they remain largely overlooked in in vitro models used in preclinical research. One major barrier to rigorously testing the role of circadian rhythms in these models is the lack of accessible tools that seamlessly integrate into standard culture setups and are capable of sustainably delivering time cues to cells and tissues in long term experiments. Here, we present the ThermoClock, a low-cost, Arduino-based automated temperature control system capable of delivering independent temperature programs to multiple cultures simultaneously. Using circadian reporter U2OS cell lines …
Betwixt Two Dams: Persistence And Angler Use Of Two Trout Taxa In A Western Nebraska Tailwater Fishery, Lauren R. Allex
Betwixt Two Dams: Persistence And Angler Use Of Two Trout Taxa In A Western Nebraska Tailwater Fishery, Lauren R. Allex
Biology Theses, Dissertations, and Student Creative Activity
Stocking catchable-sized trout is a widely used management strategy to create and maintain recreational fisheries. However, the success of these programs relies on if the fish is caught and how long the fish remain available to anglers. Lake Ogallala is a dynamic tailwater cool-water reservoir that has been managed as a salmonid fishery since 1941 where Nebraska Game and Parks Commission (NGPC) has stocked 8 different salmonids to maintain a recreational fishery. Currently, NGPC is stocking Rainbow Trout Oncorhynchus mykiss and Cutbow Trout Oncorhynchus mykiss x clarkii.
In order to understand the angler dynamics of this fishery, creel surveys collected …
Identify And Widen Bottlenecks In The Asexual Restoration Of Endangered Orbicella Faveolata Boulder Coral, Whitney Schwab
Identify And Widen Bottlenecks In The Asexual Restoration Of Endangered Orbicella Faveolata Boulder Coral, Whitney Schwab
All HCAS Student Capstones, Theses, and Dissertations
Landscape-scale coral reef restoration is constrained by the context-dependent responses of corals to environmental and ecological conditions throughout a region, and identifying factors affecting the growth and survival of key reef-building species is essential for maximizing restoration success. In collaboration with Nova Southeastern University (NSU), the University of Miami (UM), and Mote Marine Laboratory, this study evaluated the relative effects of intrinsic factors (putative genotype and source colony location) and extrinsic factors (ex-situ nursery system characteristics, in-situ nursery location, nursery type (ex-situ vs. in-situ), and environmental conditions) on Orbicella faveolata tissue regeneration and survival following fragmentation. Corals …
Water Dogs-Master Gardener Driven Landscape Water And Soil Conservation Program, Sarah J Browning, Kelly Feehan, Nicole Stoner, Roch Gaussion, Elizabeth Exstrom, John Fech, David Lott
Water Dogs-Master Gardener Driven Landscape Water And Soil Conservation Program, Sarah J Browning, Kelly Feehan, Nicole Stoner, Roch Gaussion, Elizabeth Exstrom, John Fech, David Lott
Journal of Extension
``Set it and forget it'' is a common practice with automatic irrigation systems and can lead to excessive irrigation, unhealthy root systems, and water waste. The Water Dogs program in Nebraska focuses on educating Extension Master Gardener volunteers (EMGVs). The goal was to increase their understanding of turfgrass water needs, efficient irrigation methods, and soil health management practices, and to promote greater engagement of EMGVs with homeowner audiences to share and demonstrate the knowledge gained and practices learned through ``Neighbor-to-Neighbor'' workshops. The overall goal is to conserve water and improve soil and plant health.
Systematic Review Of The Institutionalization Of Service Learning In Higher Education, Wilmer Hernan Cruz Gutierrez
Systematic Review Of The Institutionalization Of Service Learning In Higher Education, Wilmer Hernan Cruz Gutierrez
ASEAN Journal of Community Engagement
An increasing number of universities are integrating service-learning (SL) to fulfill their social mission. However, sustainable institutionalization of SL remains a persistent challenge. This study identifies and analyzes the factors, actors, and strategies that drive and inhibit SL institutionalization in higher education. Using the PRISMA 2020 guidelines, a systematic literature review analyzed 52 documents from seven academic databases (including WoS, Scopus, and ERIC). The findings were grouped into three sections: cultural (integration into institutional values/missions), process (articulation within teaching, research, and outreach), and structural dimensions (dedicated support entities). The results obtained reveal a reciprocal relationship where cultural alignment enables processual …
Exotic Two-Spined Trap-Jaw Ants (Odontomachus Haematodus) In Urban Parks Of Hattiesburg, Mississippi: Recommended Sampling Methods And Notes On Nesting Biology, Caroline M. Marley, Vinny Halsey, Lila Blackburn, Kayla D. Stan, Kaitlin M. Baudier
Exotic Two-Spined Trap-Jaw Ants (Odontomachus Haematodus) In Urban Parks Of Hattiesburg, Mississippi: Recommended Sampling Methods And Notes On Nesting Biology, Caroline M. Marley, Vinny Halsey, Lila Blackburn, Kayla D. Stan, Kaitlin M. Baudier
Midsouth Entomologist
The two-spined trap-jaw ant, Odontomachus haematodus (Linnaeus), is native to South America and was introduced to the United States via Mobile, Alabama in the mid-twentieth century. Misidentification as a native congener for several decades has inhibited the study of the ecology of O. haematodus in its introduced range within the Gulf Coastal Plain. We conducted a multimethod survey to: 1) assess the abundance of O. haematodus across urban parks in Hattiesburg, MS, the northernmost published record in this species’ exotic range, 2) establish which sampling methodologies are most effective for conducting urban surveys of O. haematodus, and 3) study …
Soybean Fermentation Broth Alleviates Indomethacin-Induced Gastric Mucosal Injury, Hsiao-Chi Wang, Yue-Jhu Chen, Hui-Yun Tsai, Jue-Liang Hsu, Yu-Kuo Chen
Soybean Fermentation Broth Alleviates Indomethacin-Induced Gastric Mucosal Injury, Hsiao-Chi Wang, Yue-Jhu Chen, Hui-Yun Tsai, Jue-Liang Hsu, Yu-Kuo Chen
Journal of Food and Drug Analysis
Dietary strategies and plant-based fermented foods have attracted increasing interest for supporting gastrointestinal health, particularly under conditions of drug-induced mucosal stress. Soybean fermentation broth (SFB), a fermented soybean-derived product, may possess enhanced nutritional and functional properties through fermentation-associated generation of bioactive peptides and antioxidant metabolites. This study evaluated the gastroprotective effects of SFB in an indomethacin-induced gastric injury model in rats and investigated the underlying mechanisms. Indomethacin markedly induced gastric ulcer formation (16.61 ± 1.38 mm2), whereas SFB pretreatment significantly attenuated ulcer development in a dose-dependent manner, reducing ulcer area to 6.66 ± 0.98, 3.89 ± 0.63, and …
Garambullo (Myrtillocactus Geometrizans) Reduces Cell Viability Via Apoptosis And Inhibits Colony Formation In Ht-29 And Sw480 Colon Cancer Cell Lines., López-Alvarez Guadalupe Soledad, Gutierrez-Silerio Gloria Yareli, García-Solís Pablo, Morales-Bárcenas Rocio, Sánchez-Pérez Yesennia, Hernández-Puga Ana Gabriela, Vergara-Castañeda Haydé Azeneth
Garambullo (Myrtillocactus Geometrizans) Reduces Cell Viability Via Apoptosis And Inhibits Colony Formation In Ht-29 And Sw480 Colon Cancer Cell Lines., López-Alvarez Guadalupe Soledad, Gutierrez-Silerio Gloria Yareli, García-Solís Pablo, Morales-Bárcenas Rocio, Sánchez-Pérez Yesennia, Hernández-Puga Ana Gabriela, Vergara-Castañeda Haydé Azeneth
Journal of Food and Drug Analysis
Garambullo (Myrtillocactus geometrizans) is a Mexican fruit rich in bioactive phytochemicals. Its fermented extract (FEG), obtained after in vitro gastrointestinal digestion and fermentation, was evaluated in HT-29 and SW480 colorectal cancer cells. FEG reduced cell viability (IC50: 2985 and 3200 μg/mL, respectively) and induced apoptosis and necrosis. In 3D assays, FEG inhibited colony formation, with complete suppression in HT-29 cells. Molecular docking further suggested that butyric acid identified in FEG interacts with Caspase-3 and RIPK1. These findings support the antiproliferative and pro-death effects of FEG in colorectal cancer models.
Gut Microbiota-Mediated Modulation Of Circadian Rhythms: Physiological And Molecular Impacts Of Dietary Composition And Feeding Time, Yen-Chun Koh, Chun-Che Chang, Min-Hsiung Pan
Gut Microbiota-Mediated Modulation Of Circadian Rhythms: Physiological And Molecular Impacts Of Dietary Composition And Feeding Time, Yen-Chun Koh, Chun-Che Chang, Min-Hsiung Pan
Journal of Food and Drug Analysis
Circadian rhythms regulate fundamental aspects of physiology and behavior. The disruption of circadian rhythms has been associated with metabolic disorders, cardiovascular disease, obesity, and impaired immune function. Feeding behavior and gut microbiota represent two essential nodes within this regulatory network, as both are highly responsive to environmental cues such as diet composition and sleep-wake cycles. Research has shown that high-fat diets, excessive fructose, and chronic alcohol consumption perturb peripheral circadian rhythms and impair metabolic pathways, contributing to obesity and insulin resistance. Conversely, dietary interventions such as time-restricted feeding and macronutrient-specific entrainment can restore rhythmic gene expression and prevent metabolic pathologies. …
Benefits And Risks Of Consuming Cannabis Sativa L. In Food, Ewa Matyjaszczyk, Maria Śmiechowska
Benefits And Risks Of Consuming Cannabis Sativa L. In Food, Ewa Matyjaszczyk, Maria Śmiechowska
Journal of Food and Drug Analysis
Cannabis sativa L. or hemp is a cosmopolitan, multi-purpose plant and area of its cultivation has been growing in recent years. Its public perception is influenced by potential to produce narcotic substances. However, hemp seed can be a valuable source of nutrients for humans and may be of particular interest in more sustainable food consumption patterns, including vegetarian and flexitarian diets.
The paper presents benefits and risks of hemp seeds in case of their consumption in food. Low cannabinoids varieties are considered only. The biological activity of cannabinoids and related effects are considered out of scope of the study.
Nutritional …
Microplastic Effect On Behavior Of Nudibranch (Berghia Stephanieae); A Trophic Transfer Study, Isabela Salina Fernandes Beneli
Microplastic Effect On Behavior Of Nudibranch (Berghia Stephanieae); A Trophic Transfer Study, Isabela Salina Fernandes Beneli
Electronic Theses and Dissertations 2020 - Present
With the continuous rise in economic supply and demand, an enormous increase in waste, litter, and pollution has been seen globally, with plastic pollution being the most abundant category. Microplastic (< 5 mm), derived from larger plastics, pollution is intensely widespread across marine ecosystems and can be transferred across trophic levels through predator-prey interactions. Recent studies have shown that ingestion of MPs can damage cells, tissues, and internal organs and increases oxidative stress leading to malformations, reduced feeding and growth, , and slower developmental rates in a wide array of organisms. This study examined the trophic transfer of microplastics (MPs) from the anemone Exaiptasia pallida to its specialist predator Berghia stephanieae, and evaluated the effects of exposure on predator behavior. A dose-response experiment demonstrated that MP retention in E. pallida decreased over time, although higher exposure concentrations resulted in greater initial microplastic concentrations. Trophic transfer to B. stephanieae was confirmed through feeding experiments. Behavioral assays revealed that B. stephanieae did not exhibit a preference between MP-exposed and control prey. However, microplastic …
What Does Sentience Mean At The Neural Level?, Björn Brembs
What Does Sentience Mean At The Neural Level?, Björn Brembs
Animal Sentience
Jonathan Birch's (2025) LSE criteria for sentience include motivational trade-offs, exemplified by C. elegansweighing hunger against desiccation risk. Yet once the neural circuit is known, this "trade-off" reduces to a single inhibitory synapse—an ‘elemental’ account discrediting the ‘molar’ one. My commentary illustrates the same discrepancy in Drosophila: dopaminergic ramping during courtship as it progressively suppresses threat-detecting neurons; so persistence past danger reflects recalibrated valuation rather than a weighed decision. As neurobiology increasingly discovers such discrepancies, all criteria resting on behavioral classifications risk being defined away without altering the behavior's validity.
Climate Change And Desert Ecosystem Resilience: A Systematic Review Of Impacts, Adaptation Strategies, And Sustainability Pathways, Ghada Abd Elsattar Mohammed Oraby, Garmat Zahra
Climate Change And Desert Ecosystem Resilience: A Systematic Review Of Impacts, Adaptation Strategies, And Sustainability Pathways, Ghada Abd Elsattar Mohammed Oraby, Garmat Zahra
Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi
Desert ecosystems are among the most climate-sensitive environments on Earth, where rising temperatures, altered precipitation regimes, and increasing aridity threaten ecosystem stability, biodiversity, and ecological functioning. Despite covering more than one-third of the global land surface, a comprehensive understanding of how climate change affects desert ecosystem resilience and the effectiveness of adaptation strategies remains limited. This study conducted a systematic review following the PRISMA framework to evaluate the impacts of climate change on desert ecosystem resilience and to identify effective adaptation and restoration pathways. A total of 16 high-quality studies were selected from 403 records retrieved from the Scopus database. …
Surveys For Rare Springsnails In Southeast Oregon, 2025 With A Focus On The Donner Und Blitzen Pebblesnail (Fluminicola Insolitus), Jesse Laney
Institute for Natural Resources Publications
The Donner und Blitzen pebblesnail (Fluminicola insolitus) is a critically imperiled (G1/S1) freshwater snail historically known from a single spring, Page Springs, in the Donner und Blitzen River drainage of Harney County, Oregon. The species was petitioned for listing under the U.S. Endangered Species Act in February 2024. On January 26, 2026, the U.S. Fish and Wildlife Service published a positive 90-day finding initiating species status review (USFWS 2026).
In August 2025, the Oregon Biodiversity Information Center (ORBIC) at Portland State University, in coordination with the Nevada Division of Natural Heritage (NDNH), the U.S. Fish and Wildlife Service (USFWS), and …
Land Conversion, Food Security, And Deforestation In Indonesia: Evidence From Farmer-Level Decisions, Mohammad Rondhi, Rizky Yanuarti, Anik Suwandari, Joni Murti Mulyo Aji, Rokhani Rokhani, Ebban Bagus Kuntadi, Subhan Arif Budiman, Yasuhiro Mori, Takumi Kondo, Orawan Srisompun
Land Conversion, Food Security, And Deforestation In Indonesia: Evidence From Farmer-Level Decisions, Mohammad Rondhi, Rizky Yanuarti, Anik Suwandari, Joni Murti Mulyo Aji, Rokhani Rokhani, Ebban Bagus Kuntadi, Subhan Arif Budiman, Yasuhiro Mori, Takumi Kondo, Orawan Srisompun
Journal of Environmental Science and Sustainable Development
Agricultural land conversion (ALC) creates a dual sustainability challenge: the loss of productive farmland to urban expansion and the conversion of forested land into new agricultural areas. Farmland loss may reduce food production capacity, while forest conversion for agriculture may increase environmental degradation. These facts create a structural policy dilemma for Indonesia: safeguarding food security while simultaneously preventing deforestation. This study examines the patterns and drivers of land conversion in Indonesia over the past decade, with a focus on its implications for food security and deforestation. Using Indonesian Farmers Income Survey (Survei Pendapatan Petani, SPP) from 2004 (n …
Governance, Culture, And Law: The Expanding Scope Of Environmental Science And Sustainable Development Research, Ahyaudin Sodri, Herdis Herdiansyah
Governance, Culture, And Law: The Expanding Scope Of Environmental Science And Sustainable Development Research, Ahyaudin Sodri, Herdis Herdiansyah
Journal of Environmental Science and Sustainable Development
Environmental science emerged as a discipline based on physical measurements, such as soil pollutant levels (Ailijiang et al., 2022), ecological restoration (Yue et al., 2026), city surface temperature (Shafizadeh-Moghadam et al., 2025), and microbial density in air samples (Hayleeyesus & Manaye, 2014). However, its objects of study increasingly extend beyond the confines of the laboratory. Questions that were once sufficiently answered with measurement data now require answers through draft laws, Constitutional Court decisions, financial reports of mining companies, and even traditional ritual discourses governing community access to forests. In other words, environmental …
Abstracts Of The 71st Annual Conference Of The Mississippi Association Of Entomologists, Nematologists, And Plant Pathologists (Maenpp)
Midsouth Entomologist
October 27 & 28, 2025
Effects Of Scion And Rootstock On Arbuscular Mycorrhizal Symbiosis And Spore Communities In Vitis Vinifera, Nicholas Vergara, Stephen Bentivenga
Effects Of Scion And Rootstock On Arbuscular Mycorrhizal Symbiosis And Spore Communities In Vitis Vinifera, Nicholas Vergara, Stephen Bentivenga
STEM Student Research Symposium Posters
Arbuscular mycorrhizal fungi (AMF) are obligate root symbionts that extend host nutrient uptake in exchange for photosynthate. Nearly all commercial wine grapes (Vitis vinifera) are grafted onto American rootstocks selected for phylloxera resistance, drought tolerance, and vigor, meaning the root system interfacing with soil fungi is genetically distinct from the fruiting scion. Whether root system origin shapes AMF association remains poorly resolved, particularly in sandy, low-fertility soils. We compared AMF colonization and spore communities across four rootstock–scion combinations (Cabernet Franc and Merlot scions, own-rooted and riparian rootstock) at William Heritage® Winery in Mullica Hill, NJ. Fine roots were cleared, stained, …
Comparison Of Arbuscular Mycorrhizal Fungal Colonization And Spore Communities Between Clover-Dominated Cover Crop And Restored Native Grass Systems, Nicholas Vergara, Stephen Bentivenga
Comparison Of Arbuscular Mycorrhizal Fungal Colonization And Spore Communities Between Clover-Dominated Cover Crop And Restored Native Grass Systems, Nicholas Vergara, Stephen Bentivenga
STEM Student Research Symposium Posters
Arbuscular mycorrhizal fungi (AMF) are obligate root symbionts that extend host nutrient uptake in exchange for photosynthate. Restored native grasslands and cover-cropped fields represent contrasting management strategies applied to former conventional farmland, differing in both tillage frequency and plant diversity, yet how these strategies shape AMF association in sandy, low-fertility soils remains largely understudied. We compared AMF colonization and spore communities between two adjacent sites converted approximately three years prior at the Bishop Farmstead, Southampton Township, NJ: a restored grassland dominated by Panicum virgatum and an agricultural field under white and red clover cover (Trifolium repens, T. pratense). Fine roots …
Oncogenic E-Cadherin-Dependent Metastasis And Potential Therapeutic Interventions, Madison K. Duenas, Anjela Anand, Paige Cano, Ralph Boccia, Mary Alpaugh
Oncogenic E-Cadherin-Dependent Metastasis And Potential Therapeutic Interventions, Madison K. Duenas, Anjela Anand, Paige Cano, Ralph Boccia, Mary Alpaugh
STEM Student Research Symposium Posters
Oncogenic E-cadherin-dependent metastasis is a paradoxical mechanism of cancer progression whereby E-cadherin, a cell-to-cell adhesion protein that normally suppresses tumor invasion, instead promotes the formation of cohesive cell tumor clusters that collectively invade surrounding tissues and metastasize. This phenomenon has been extensively studied using inflammatory breast cancer (IBC) models, including the MARY-X xenograft and SUM149 cell line, while comparisons with other breast cancer models such as MDA-MB-231 continue to provide insight into E-cadherin-independent metastatic mechanisms. This project reviews recent literature investigating the molecular mechanisms behind it and evaluates emerging therapeutic strategies targeting E-cadherin-associated cellular pathways. Laboratory techniques, including spheroid generation …
Stability Of The Apogee Galvanic Cell Sensors In The Utah State University Biological Oxygen Demand System, Tia Lawrence, Carson Richards, Bruce Bugbee
Stability Of The Apogee Galvanic Cell Sensors In The Utah State University Biological Oxygen Demand System, Tia Lawrence, Carson Richards, Bruce Bugbee
Techniques and Instruments
The Utah State University Crop Physiology Laboratory has developed a six-chamber biological oxygen demand (BOD) system to quantify respiration (Kusuma & Bugbee, 2020). Like all instruments, accuracy depends on the ability to get a zero in empty containers. Here we report the signal output and zero stability in empty containers over a five-day interval.
Modeling Nonequilibrium Community Dynamics Of Bivalves In The Indian River Lagoon, Jada Lee Brown
Modeling Nonequilibrium Community Dynamics Of Bivalves In The Indian River Lagoon, Jada Lee Brown
Electronic Theses and Dissertations 2020 - Present
Benthic infaunal communities are widely-used indicators for assessing estuarine health, especially in systems that experience frequent disturbances and hydrological fluctuations. However, using benthic infauna to predict ecosystem responses to future disturbances remains a challenge. The Indian River Lagoon (IRL), spanning 40% of Florida's east coast, is a prime example of a complex estuary that has experienced decades of hydrological alterations leading to reduced water quality, sediment composition, and biodiversity. To assess benthic bivalve community dynamics in response to disturbances, an emerging Empirical Dynamic Modeling (EDM) approach was applied to a large test dataset comprising 17 years of benthic bivalve abundances …
From Anaerobic Digesters To The Human Gut: Ecological Responses Of Microbiomes To Environmental And Biological Perturbations, Maliea Annholden Nipko
From Anaerobic Digesters To The Human Gut: Ecological Responses Of Microbiomes To Environmental And Biological Perturbations, Maliea Annholden Nipko
Theses and Dissertations
Microbial communities regulate essential ecological and metabolic processes across both engineered and host-associated ecosystems. Although these systems differ substantially in composition and function, they are governed by common ecological principles including community succession, resilience, species interactions, and responses to environmental and biological perturbations. This dissertation investigates how perturbations influence microbiome structure, function, and stability through three complementary studies spanning anaerobic digestion and the human gut microbiome. First, the effects of an extremophilic biological pretreatment using Caldicellulosiruptor bescii were evaluated in industrial-scale anaerobic digesters treating dairy manure. High- temperature pretreatment substantially altered microbial community composition, with bacterial populations remaining metabolically active …
Bridging The Gap In Science Research: Preparing Students For College- Level Research In The Sciences, Victoria Helwig, Yaoguang Li
Bridging The Gap In Science Research: Preparing Students For College- Level Research In The Sciences, Victoria Helwig, Yaoguang Li
UConn Library Presentations
Many first-year students enter college unprepared to fully engage with scientific literature and academic library resources. Drawing on experiences from academic librarians working with STEM students, this session explores common gaps in science research skills, including navigating databases, identifying scholarly sources, and understanding the structure of scientific literature. Participants will be introduced to practical strategies and classroom-ready activities to better prepare students for college-level research. Discussion questions: What science research skills do students struggle with most when entering college? How can high school instruction better support these skills? Where can librarians and educators collaborate to support student success?
Environmental Dna For Endangered Freshwater Mussel Monitoring: A Review On Global Synthesis Of Edna Methods, Challenges, And Innovative Strategies, Mizanur Rahman, Md. Saydur Rahman, Richard J. Kline
Environmental Dna For Endangered Freshwater Mussel Monitoring: A Review On Global Synthesis Of Edna Methods, Challenges, And Innovative Strategies, Mizanur Rahman, Md. Saydur Rahman, Richard J. Kline
School of Earth, Environmental, & Marine Sciences Faculty Publications
Freshwater mussels (family Unionidae) are among the most endangered aquatic species worldwide, making effective monitoring vital for their conservation. Traditional surveys are laborious, time-consuming, and often miss rare or low-density populations. Environmental DNA (eDNA) is a highly sensitive, non-invasive approach for freshwater mussel detection and monitoring; however, uncertainties in ecological interpretation continue to limit its broader application in freshwater biodiversity monitoring. We conducted a systematic review of 49 peer-reviewed studies, identified through an extensive literature search, to assess temporal research trends, methodological advancements, ecological contexts, and regulatory readiness of freshwater mussel eDNA monitoring. Findings show that freshwater mussel eDNA research …
Interpretable Ai-Enabled Decision Support For Drinking-Straw Substitution Using Per-Use Greenhouse-Gas Indicators And User-Review Evidence, Ahmed Barakat Hosseny, Marwa Said Hassan, Shymaa Khamis, Randa Osman, Gassan Hodaifae, Jie Tang, Shaoshan Liu
Interpretable Ai-Enabled Decision Support For Drinking-Straw Substitution Using Per-Use Greenhouse-Gas Indicators And User-Review Evidence, Ahmed Barakat Hosseny, Marwa Said Hassan, Shymaa Khamis, Randa Osman, Gassan Hodaifae, Jie Tang, Shaoshan Liu
Basic Science Engineering
Plastic drinking straws are a visible single-use plastic product, yet selecting suitable substitutes remains challenging because literature-derived climate evidence and reported user experience are rarely evaluated together. This study develops and demonstrates an interpretable AI-enabled decision-support workflow that integrates literature-derived per-use greenhouse gas (GHG) indicators with review-derived user evidence extracted from online customer reviews using natural language processing (NLP). Drinking-straw alternatives were used as an information-rich case study. The integrated assessment combined a GHG-derived score, a user-experience feature score, and rating-based consumer approval within a transparent multi-criteria decision analysis (MCDA) under four predefined decision-priority scenarios. Among the five shortlisted materials …