Nanoscience and Nanotechnology Commons^™

Study On The Chemical And Mechanical Stability Of Polymer Nanofluidic Biosensors, Dae Won Kim

LSU Master's Theses

Polymer nanofluidic devices have great potential to replace silicon (Si) and glass-based nanofluidic devices in biomedical applications due to their advantages such as low material and fabrication cost, various physicochemical properties, well-developed surface modification protocol, and low electrical noises for electrical measurements. In nanofluidic sensing applications, single molecules such as DNA are introduced into the fabricated nanochannel or nanopore, measuring their physicochemical properties optically or electrically. The properties of materials for nanofluidic devices have a significant role in the performance of the devices, such as DNA translocation and device stability.

Among several nanoscale fluidic physics, surface charge density is a …

Diamond-Based Microelectrodes Fabricated Using The Diamond Growth Side For Neural Sensing, Cory Rusinek, Bin Fan, Cort H. Thompson, Monica Setien, Yue Guo, Robert Rechenberg, Yan Gong, Arthur J. Weber, Michael F. Becker, Erin Purcell, Wen Li

Chemistry and Biochemistry Faculty Research

Diamond possesses many favorable properties for biochemical sensors, including biocompatibility, chemical inertness, resistance to biofouling, an extremely wide potential window, and low double-layer capacitance. The hardness of diamond, however, has hindered its applications in neural implants due to the mechanical property mismatch between diamond and soft nervous tissues. Here, we present a flexible, diamond-based microelectrode probe consisting of multichannel boron-doped polycrystalline diamond (BDD) microelectrodes on a soft Parylene C substrate. We developed and optimized a wafer-scale fabrication approach that allows the use of the growth side of the BDD thin film as the sensing surface. Compared to the nucleation surface, …

Synthesis, Self-Assembly And High-Pressure Properties Of Nanoparticles And Hybrid Nanocomposites, Lingyao Meng

Nanoscience and Microsystems ETDs

Nanoparticles have gained significant scientific interests owing to their unique structural dimensions, size- and shape-tunable properties, and numerous fascinating applications, from opto-electronics, sensor devices, to energy, environmental, and medical fields. Furthermore, the synergistic integration of other materials, including organic polymers, with nanoparticles provides new opportunities and strategies to obtain nanocomposites with superior properties and functionalities. While there is already significant research on the synthesis and characterizations of nanoparticles and hybrid nanocomposites, some research questions, such as how to design and control the interfacial morphology in polymer/nanoparticle hybrid nanocomposites, how to synthesize metal- organic framework (MOF) nanoparticles in well-defined and uniform …

Comparison Of Plantar Pressure Profile Of Young Adults During Training On Elliptical Devices And Overground Walking: A Pilot Study, Guilherme Manna Cesar, Thad W. Buster, Judith M. Burnfield

Department of Mechanical and Materials Engineering: Faculty Publications

Background: Elliptical training may offer advantages over other cardiorespiratory exercises for those requiring podiatric care, since its constant double-limb support diminishes recurring high-impact plantar forces while allowing exercise in a functional, upright posture. Unknown is the impact of distinct elliptical models, that can alter user’s body mechanics, on potential variations in plantar pressure patterns.

Purpose: To compare plantar pressure variables while exercising on four ellipticals and walking.

Methods: For this cross-sectional pilot study, plantar pressure data were recorded from ten young adults while exercising on four ellipticals (True, Octane, Life Fitness, SportsArt) and walking overground. One-way repeated measures ANOVA identified …

Nonlinear Nanophotonic Devices In The Ultraviolet To Visible Wavelength Range, Jinghan He, Hong Chen, Jin Hu, Jingan Zhou, Yingmu Zhang, Andre Kovach, Constantine Sideris, Mark C. Harrison, Yuji Zhao, Andrea M. Armani

Engineering Faculty Articles and Research

Although the first lasers invented operated in the visible, the first on-chip devices were optimized for near-infrared (IR) performance driven by demand in telecommunications. However, as the applications of integrated photonics has broadened, the wavelength demand has as well, and we are now returning to the visible (Vis) and pushing into the ultraviolet (UV). This shift has required innovations in device design and in materials as well as leveraging nonlinear behavior to reach these wavelengths. This review discusses the key nonlinear phenomena that can be used as well as presents several emerging material systems and devices that have reached the …

Magnetically Induced Carrier Distribution In A Composite Rod Of Piezoelectric Semiconductors And Piezomagnetics, Guolin Wang, Jinxi Liu, Wenjie Feng, Jiashi Yang

Department of Mechanical and Materials Engineering: Faculty Publications

In this work, we study the behavior of a composite rod consisting of a piezoelectric semiconductor layer and two piezomagnetic layers under an applied axial magnetic field. Based on the phenomenological theories of piezoelectric semiconductors and piezomagnetics, a one-dimensional model is developed from which an analytical solution is obtained. The explicit expressions of the coupled fields and the numerical results show that an axially applied magnetic field produces extensional deformation through piezomagnetic coupling, the extension then produces polarization through piezoelectric coupling, and the polarization then causes the redistribution of mobile charges. Thus, the composite rod exhibits a coupling between the …

Preparations Of Nano-MnoX/Ti Electrocatalytic Membrane Electrode For Catalytic Oxidation Of Cyclohexane Using Intermittent Electrodeposition, Xue Zhou, Hong Wang, Zhen Yin, Yu-Jun Zhang, Jian-Xin Li

Journal of Electrochemistry

Cyclohexanone and cyclohexanol (KA oil) obtained from highly selective oxidation of cyclohexane (CHA) show important industrial value and application prospects. In this work, the intermittent electrodeposition was developed to prepare nano-MnO_x catalyst loading porous tubular titanium membrane electrode (MnO_x/Ti), which was employed to constitute an electro-catalytic membrane reactor (ECMR) for the oxidation of cyclohexane to produce cyclohexanol and cyclohexanone. The surface morphology, crystal structure and electrochemical property of the catalysts were characterized by FESEM, XRD and electrochemical workstation, respectively. The results show that the catalyst prepared by the intermittent electrodeposition displayed nano-flower-like γ-MnO₂. Compared with …

Synthesis And Raman Study Of Hollow Core-Shell Ni1.2Co0.8P@N-C As An Anode Material For Sodium-Ion Batteries, Jia-Hui Chen, Xiao-Bin Zhong, Chao He, Xiao-Xiao Wang, Qing-Chi Xu, Jian-Feng Li

Journal of Electrochemistry

With the increasing demand for large-scale energy storage, great progress has been made in discovering new advanced energy storage materials. Sodium-ion batteries (SIBs) have attracted much attention in recent years due to their use of abundant sodium resources and their comparable electrochemical capacity to lithium-ion batteries (LIBs). In this paper, we developed novel hollow core-shell Ni-Co bimetallic phosphide nanocubes with N-doped carbon coatings (Ni_1.2Co_0.8P@N-C) as the anode material for SIBs. The material was synthesized through a low-temperature phosphorization method using resorcinol formaldehyde (RF) resin coating with a Ni-Co Prussian blue analogue (PBA) as a template and …

Hyaluronic Acid Coated Targeted Lipid Micellar Nanoparticle As A Delivery Vehicle For Lapatinib And Ketoconazole In Egfr Mutated Lung Cancer, Nadia Tasnim Ahmed

USF Tampa Graduate Theses and Dissertations

Background: According to the American Cancer Society, lung cancer was accountable for over 142,000 deaths in the USA in 2019. Common mutations related to lung cancer mainly occur in TP53, EGFR, and KRAS genes. Lapatinib is a small molecule tyrosine kinase inhibitor which acts reversibly on both epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2). Overexpression of EGFR leads to increased production and signaling of proteins that cause upregulation of cellular proliferation, cholesterol synthesis and resistance to apoptosis. Ketoconazole is an imidazole antifungal agent which works principally by inhibiting the enzyme cytochrome P450 14α-demethylase (CYP51A1) …

Transcriptome Studies On The Toxicity Of Silica Nanoparticles, Shih-Yi Hsu

USF Tampa Graduate Theses and Dissertations

Nanotechnology enables more precise harmony in health condition via reducing the dosage amount, improving the delivery of hydrophobic drugs, more specific targeting to the cancerous sites, and so on. Nevertheless, issues regarding the toxicity of nanotechnology have begun to call for attention several decades later after the innovation of nanotechnology. Tools about risk management of nanotechnology have been developed, but recently not much evidence recognizes the toxicity of nanoparticles (NPs) except for some animal studies, which demonstrated organ damage after the exposure to NPs. Toxicogenomic approach refers to the method utilizing gene expression to evaluate the chemical toxicity. Databases as …

Lstm-Based Anomaly Detection For Non-Linear Dynamical System, Yue Tan, Chungjing Hu, Kuan Zhang, Kan Zeng, Ethan A. Davis, Jae Sung Park

Department of Mechanical and Materials Engineering: Faculty Publications

Anomaly detection for non-linear dynamical system plays an important role in ensuring the system stability. However, it is usually complex and has to be solved by large-scale simulation which requires extensive computing resources. In this paper, we propose a novel anomaly detection scheme in non-linear dynamical system based on Long Short-Term Memory (LSTM) to capture complex temporal changes of the time sequence and make multi-step predictions. Specifically, we first present the framework of LSTM-based anomaly detection in non-linear dynamical system, including data preprocessing, multi-step prediction and anomaly detection. According to the prediction requirement, two types of training modes are explored …

Geometric Optimization Of Plasmonic Nanostructure Arrays On Mwir Hgcdte (Mct), Nagendrababu Vanamala, Kevin C. Santiago, Naresh C. Das, Samuel Keith Hargrove

Mechanical and Manufacturing Engineering Faculty Research

Mercury Cadmium Telluride (MCT) is a primary absorber material used in most infrared (IR) detection technologies. Our previous studies show that the optical absorbance profile of MCT in the mid-infrared region can be enhanced by 13% under ambient conditions via integrating periodic Indium Tin Oxide (ITO) nanostructures. Here, we focus on the geometrical parameterization and optimization of ITO nanostructure arrays. We simulate several types of geometries, their corresponding effective absorption profiles, E-field distribution, and optimal geometric parameters. This work may lead to improved light collection and absorption edge engineering, as MCT continues to be the material of choice in IR …

Detection Of Hydroxyl Radicals Using Cerium Oxide/Graphene Oxide Composite On Prussian Blue, Surachet Duanghathaipornsuk, Sushil R. Kanel, Emily F. Haushalter, Jessica Ruetz, Dong-Shik Kim

Faculty Publications

A composite sensor consisting of two separate inorganic layers of Prussian blue (PB) and a composite of cerium oxide nanoparticles (CeNPs) and graphene oxide (GO), is tested with •OH radicals. The signals from the interaction between the composite layers and •OH radicals are characterized using cyclic voltammetry (CV). The degradation of PB in the presence of H₂O₂ and •OH radicals is observed and its impact on the sensor efficiency is investigated. The results show that the composite sensor differentiates between the solutions with and without •OH radicals by the increase of electrochemical redox current in the presence …

Synthesis And Characterization Of Porous Carbon Composite Derived From Biomass Waste For Supercapacitor Application, Cheng Kim Sim

Student Works (2020-2029)

Energy storage devices have gradually dominated human daily activities and indispensable to economy development such as supercapacitor and battery. There are few factors determining the performance of supercapacitor and active material is one of the crucial. Therefore, biomass such as pineapple peel (PP) and green waste (GW) were preferred and prior mixed with manganese and tin carbonate to synthesize carbon composite (PP/GW-ZMO and PP/GW-ZTO) via combustion. Brunauer–Emmett–Teller (BET) was employed to study the textural properties with the highest specific surface area obtained in PP-C (1765.92 m2g-1) and GW-C (1613.92 m2g-1). The existence of composite materials was examined using x-ray diffraction …

Fabrication Of Nanoscale Columnar Diodes By Glancing Angle Deposition, Jacob D. Weightman

Macalester Journal of Physics and Astronomy

Glancing angle deposition (GLAD) is a process in which thin films are deposited onto a substrate with obliquely incident vapor together with precisely controlled azimuthal substrate rotation. Ballistic shadowing effects due to the oblique incidence produce nanoscale structures, and a variety of feature shapes, including tilted columns, helices, and vertical columns can be achieved by varying the azimuthal rotation during the deposition process. Due to this control of morphology and the compatibility of the process with a wide variety of materials, GLAD films have found applications in a variety of fields including sensing, photonics, photovoltaics, and catalysis, where they are …

The Artificial Leaf: An Investigation Into The Sociotechnical Integration Of New Solar Energy Innovations, Alexandra K. Treml, Jamie M. Mears

Senior Honors Projects, 2020-current

Increasing global demand, combined with the volatility of fossil fuels, has called for a large-scale increase in renewable energy production. Photovoltaics hold significant potential, but by nature, solar energy is intermittent and lacks dispatchability. Researchers around the world are working to create innovative solutions that utilize semiconductors found in solar cell technologies in new ways. This project harnesses photoelectrochemical water-splitting, which uses light energy to dissociate water molecules into hydrogen and oxygen. When the water-splitting device is submerged in saltwater and illuminated by sunlight, oxygen and hydrogen gas are produced on opposite surfaces, and can be either released or stored …

Size-Dependent Inhibitory Effects Of Antibiotic Nanocarriers On Filamentation Of E. Coli, Preeyaporn Songkiatisak, Feng Ding, Pavan Kumar Cherukuri, Xiao-Hong Nancy Xu

Chemistry & Biochemistry Faculty Publications

Multidrug membrane transporters exist in both prokaryotic and eukaryotic cells and cause multidrug resistance (MDR), which results in an urgent need for new and more effective therapeutic agents. In this study, we used three different sized antibiotic nanocarriers to study their mode of action and their size-dependent inhibitory effects against Escherichia coli (E. coli). Antibiotic nanocarriers (AgMUNH–Oflx NPs) with 8.6 × 10², 9.4 × 10³ and 6.5 × 10⁵ Oflx molecules per nanoparticle (NP) were prepared by functionalizing Ag NPs (2.4 ± 0.7, 13.0 ± 3.1 and 92.6 ± 4.4 nm) with a monolayer …

Probing Nanoelectroporation And Resealing Of The Cell Membrane By The Entry Of Ca2+ And Ba2+ Ions, Wenfei Bo, Mantas Silkunas, Uma Mangalanathan, Vitalij Novickij, Maura Casciola, Iurii Semenov, Shu Xiao, Olga N. Pakhomova, Andrei G. Pakhomov

Bioelectrics Publications

The principal bioeffect of the nanosecond pulsed electric field (nsPEF) is a lasting cell membrane permeabilization, which is often attributed to the formation of nanometer-sized pores. Such pores may be too small for detection by the uptake of fluorescent dyes. We tested if Ca²⁺, Cd²⁺, Zn²⁺, and Ba²⁺ ions can be used as nanoporation markers. Time-lapse imaging was performed in CHO, BPAE, and HEK cells loaded with Fluo-4, Calbryte, or Fluo-8 dyes. Ca²⁺ and Ba²⁺ did not change fluorescence in intact cells, whereas their entry after nsPEF increased fluorescence within <1 ms. The threshold for one 300-ns pulse was at 1.5–2 kV/cm, much lower than >7 …

Characterization Of Avidin And Case9 Single Protein Molecules By A Solid-State Nanopore Device, Haopeng Li

Graduate Theses and Dissertations

The shape and charge of a protein play significant roles in protein dynamics in the biological system of humans and animals. Characterizing and quantifying the shape and charge of a protein at the single-molecule level remains a challenge. Solid-state nanopores made of silicon nitride (SiNx) have emerged as novel platforms for biosensing such as diagnostics for single-molecule detection and DNA sequencing. SSN detection is based on measuring the variations in ionic conductance as charged biomolecules translocate through nanometer-sized channels driven by an external voltage applied across the membrane. In this paper, we observe the translocation of asymmetric cylindrical structure CRISPR-Cas9 …

Construction And Electrochemical Performance Of Garnet-Type Solid Electrolyte/Al-Li Alloy Interface, Jia-Lin Ma, Hong-Chun Wang, Zheng-Liang Gong, Yong Yang

Journal of Electrochemistry

Garnet-type solid electrolyte is a newly developed Li ion conductor and promising in the application of all-solid-state batteries. However, Garnet is incompatible with Li anode, which restricts the application of Garnet-type solid batteries. In order to improve the contact between Garnet-type solid electrolyte and Li electrode, a composite anode which contains Al-Li alloy (Al₄Li₉) was prepared as an electrode. Al-Li alloy has many advantages such as easy preparation, low cost, simple post-treatment and high capacity. Garnet-type Li_6.5La₃Zr_1.75W_0.25O₁₂ (LLZWO) was synthesized via solid-state reaction. Garnet solid electrolyte has …