Biomedical Engineering and Bioengineering Commons^™

Representativeness Evaluation Of Delta-Flux Eddy Covariance Towers For Assessing Greenhouse Gas Emissions From Rice Fields In The Mid-South Region, Katherine Skiles

Biological and Agricultural Engineering Undergraduate Honors Theses

Rice grown in 5 states across the Mid-South (AR, LA, MS, TX, and MO) account for nearly 80% of all domestic U.S. rice production. Methane emissions produced during rice farming and the large seasonal water demand to maintain flooded fields have created a need for alternative irrigation research that can reduce methane emissions and conserve water. Structures called eddy covariance towers (ECTs) can observe methane and other flux responses to changing irrigation styles, and their data is shared across flux tower networks such as Delta-Flux in the Mid-South. The Delta-Flux network is relatively new, and its data-sharing capacity is not …

Hierarchical Based Classifcation Method Based On Fusion Ofgaussian Map Descriptors Foralzheimer Diagnosis Using T1‑Weighted Magnetic Resonance Imaging, Nourhan Zayed, Shereen E. Morsy, Inas A. Yassine

Mechanical Engineering

Alzheimer’s disease (AD) is considered one of the most spouting elderly diseases. In 2015, AD is reported the US’s sixth cause of death. Substantially, non-invasive imaging is widely employed to provide biomarkers supporting AD screening, diagnosis, and progression. In this study, Gaussian descriptors-based features are proposed to be efcient new biomarkers using Magnetic Resonance Imaging (MRI) T1-weighted images to diferentiate between Alzheimer’s disease (AD), Mild Cognitive Impairment (MCI), and Normal controls (NC). Several Gaussian map-based features are extracted such as Gaussian shape operator, Gaussian curvature, and mean curvature. The aforementioned features are then introduced to the Support Vector Machine (SVM). …

The Effects Of Mechanical Strain On Vascular Calcification And The Canonical Wnt Pathway, Hannah E. Douglas

Theses and Dissertations

Cardiovascular disease is a significant health crisis, representing 32% of deaths worldwide in 2019. Vascular calcification (VC), a major contributor to cardiovascular disease, is a regulated biomineralization process whose exact mechanisms are unknown. Additionally, vascular smooth muscle cells (VSMCs) significantly contribute to VC by undergoing a phenotypic switch and differentiating into osteoblast-like cells. When factors like hypertension cause disturbed laminar flow in the body’s vasculature, the mechanical stress promotes the phenotypic switch and calcification of VSMCs via mechanotransduction. VC is also induced by the Wnt pathway, which is activated via mineral imbalance and mechanical stimulation. However, the exact mechanisms behind …

Analyzing Pseudomonas Aeruginosa With Bacteriophage Tags Using Photoacoustic Flow Cytometry, Jennifer C. Schinke

Electronic Theses and Dissertations

The number of daily bacterial infections is climbing and the CDC explains that this is due to the antibiotic-resistant threat in the United States. Finding a faster way of bacterial identification is necessary as it currently takes 1-4 days for a medical lab to culture and identify bacteria. Photoacoustic flow cytometry (PAFC) can be used as an alternative method resulting in swift identification within an hour (Edgar, 2019). Pseudomonas aeruginosa, cell line PA01, will be coated in up to a few hundred red dyed phages making it detectible by the photoacoustic flow cytometry system. Bacteriophages (phages) are viruses that …

Predicting Accurate Heart Attacks Using Logistic Regression, Vishal Baral, Pranati Palai, Soumen Nayak

International Journal of Computer and Communication Technology

A heart attack is one of the leading causes of death today. According to a large data population used as a training set for the algorithm for machine learning, classification is a technique for predicting the target class from input data. A difficulty in clinical data analytics is predicting heart attacks with greater precision. The focal point of this work is to analyze the heart attack dataset (Kaggle repository) to find a Machine learning classifier technique that predicts if a person is prone to a heart attack with maximum accuracy based on various health factors. The efficacy of the three …

Surface-Functionalized Silica Nanocarriers For Mitigating Water Stress In Wheat And Benefiting The Root Microbiome, Anthony Cartwright

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Changes in climate and shifting patterns of drought threaten the growth of important cash crops like wheat. The element silicon serves as a plant nutrient and shows promise for strengthening wheat against drought while remaining safe to both the crop and the positive bacteria that grow on its roots. Silicon can be added to wheat in the form of silicon-dioxide nanoparticles featuring protective coatings made from plant-beneficial nutrients. These nanoparticles can be engineered with high surface area or porous structures allowing them to be loaded with additional nutrients that can be delivered to crops. In a laboratory setting, such nanoparticles …

A Novel Brain Computer Interface Design, Steven Vogan

Senior Honors Theses

A brain computer interface (BCI) is a system which connects neural signals to a computer system. They have been used for controlling systems including robotics, on-screen computer control such as mouse movement, typing, and synthesizing audio signals. Invasive, or implanted, systems are often long-term medical solutions, or used for research where very clear signal is required. Non-invasive systems usually rely on exterior signals gathered through a headset using one or more electrode sensors. These signals are composed of sums of neuron activation potentials from brain activity and can be used to determine particular aspects of brain function. All BCIs rely …

Exploring Versatile Glycosyltransferases From Microorganisms For Natural Product Biosynthesis, Jie Ren

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This dissertation is mainly focused on exploring versatile glycosyltransferases from different microorganisms with the purpose of biosynthesizing bioactive natural product glycosides through microbial fermentation. This engineered biosynthesis approach is environmentally friendly, safe, and efficient compared with plant extraction, chemical synthesis, and enzymatic synthesis. Additionally, we applied these characterized glycosyltransferases as efficient biocatalytic tools to produce novel glycosides to expand the chemical repertoire of nature. These novel compounds showed improved water solubility and some of them exhibited enhanced stability and biological activity, which laid the foundation for the development of new therapeutic agents.

In my dissertation research, I have discovered two …

Serum Metabolomic Profiling For Colorectal Cancer Using Machine Learning, Ria Nur Puspa Sari, Diah Balqis Ikfi Hidayati, Arleni Bustami

Indonesian Journal of Medical Chemistry and Bioinformatics

Background: Colorectal cancer is one of the deadliest diseases with a high prevalence worldwide and is characterized by the appearance of adenomatous polyps in the colon mucosa which are at high risk of developing into colorectal cancer. This study aims to use serum metabolites as promising non-invasive biomarkers for colorectal cancer detection and prognostication. Differences in serum metabolites in patients with adenomatous polyps, colorectal cancer, and healthy controls are considered to be able to support the prognosis of colorectal cancer. Methods: Metabolite dataset is taken from the Metabolomic Workbench. Analysis and validation are carried out in silico using machine learning …

Multiple Ways To Implement And Infer Sentience, Nicolas Rouleau, Michael Levin

Animal Sentience

Segundo-Ortin & Calvo’s (S&C’s) thorough review of “plant neurobiology” presents evidence supporting the possibility of plant sentience. They make a compelling case that plants anticipate, assess risk, cooperate, mimic, and pursue goals, as do their animal counterparts. S&C point out that there is a double standard: behavioural patterns associated with subjective experiences in humans are considered valid for inferring cognition in non-human animals but not in diverse other systems including plants. We argue that cognitive functions, including sentience, can potentially be achieved by very different systems and their disparate substrates. We offer some context from the basal cognition literature and …

List Of 121 Papers Citing One Or More Skin Lesion Image Datasets, Neda Alipour

Other resources

No abstract provided.

A Review Of Solar Hybrid Photovoltaic-Thermal (Pv-T) Collectors And Systems, Todd Otanicar

Mechanical and Biomedical Engineering Faculty Publications and Presentations

In this paper, we provide a comprehensive overview of the state-of-the-art in hybrid PV-T collectors and the wider systems within which they can be implemented, and assess the worldwide energy and carbon mitigation potential of these systems. We cover both experimental and computational studies, identify opportunities for performance enhancement, pathways for collector innovation, and implications of their wider deployment at the solar-generation system level. First, we classify and review the main types of PV-T collectors, including air-based, liquid-based, dual air–water, heat-pipe, building integrated and concentrated PV-T collectors. This is followed by a presentation of performance enhancement opportunities and pathways for …

Predicting Corrosion Damage In The Human Body Using Artificial Intelligence: In Vitro Progress And Future Applications Applications, Michael A. Kurtz, Ruoyu Yang, Mohan S. R. Elapolu, Audrey C. Wessinger, William Nelson, Kazzandra Alaniz, Rahul Rai, Jeremy L. Gilbert

Publications

Artificial intelligence (AI) is used in the clinic to improve patient care. While the successes illustrate the impact AI can have, few studies have led to improved clinical outcomes. A gap in translational studies, beginning at the basic science level, exists. In this review, we focus on how AI models implemented in non-orthopedic fields of corrosion science may apply to the study of orthopedic alloys. We first define and introduce fundamental AI concepts and models, as well as physiologically relevant corrosion damage modes. We then systematically review the corrosion/AI literature. Finally, we identify several AI models that may be Preprint …

The Plastics Collection Reference Packet, Special Collections Research Center

Special Collections Research Center

This reference packet is an informational tool to support further research into the history of plastics—whether interested in companies, individuals within the plastics industry's history, historical plastics materials, essays, and more. All content featured within this packet was previously published on the former plastics.syr.edu website as part of a Syracuse University Libraries and Special Collections Research Center (SCRC) partnership established in 2007 with the Plastics Pioneers Association (PPA)—an association of plastics industry professionals interested in preserving the plastics industry's past.

A Dynamical Systems Approach To Characterizing Brain–Body Interactions During Movement: Challenges, Interpretations, And Recommendations, Derek C. Monroe, Nathaniel T. Berry, Peter C. Fino, Christopher K. Rhea

Rehabilitation Sciences Faculty Publications

Brain–body interactions (BBIs) have been the focus of intense scrutiny since the inception of the scientific method, playing a foundational role in the earliest debates over the philosophy of science. Contemporary investigations of BBIs to elucidate the neural principles of motor control have benefited from advances in neuroimaging, device engineering, and signal processing. However, these studies generally suffer from two major limitations. First, they rely on interpretations of ‘brain’ activity that are behavioral in nature, rather than neuroanatomical or biophysical. Second, they employ methodological approaches that are inconsistent with a dynamical systems approach to neuromotor control. These limitations represent a …

Neurocomputing And Interfacing Digital Tasting System: Research, Design, And Evaluation, Amira J. Zaylaa, Ahmad El Hajj

BAU Journal - Science and Technology

The continuous evolution in computing and interfacing has been extended to develop multi-sensory experiences in many domains such as neurological, auditory, vision, and haptic domains. So far, only a few remarkable system approaches have been approved to be serving the taste sensation digitally. Although taste sensation is linked to the brain, there is a lack of optimal neurocomputing digital taste sensation systems. Our study provides a new neurocomputing method to digitally stimulate the sense of taste by electrical stimulation on the human tongue. We aim to link chemical stimulation and electrical stimulation in order to design an electronic interface for …

Exploring The Use Of Virtual Reality In Designing And Prototyping Medical Devices, Evan Marsh

Honors Theses, University of Nebraska-Lincoln

A degree in engineering is highly sought after in the United States. Despite the grueling coursework and sacrifices involved in earning an engineering degree, the rewards after college are numerous. However, the engineering field is vast, and the degree obtained is not always the profession followed in industry. A lot of what we learn in the college of engineering is very broad and surface-level. It is worth noting that only about 10% of what engineering students learn in school is applicable in the workplace, but they wish they had learned a lot more about that 10%.

Creation Of A Hyperplane Device For Horizontal Cellular Migration Assays, Nicholas M. Bittner, Nelofar Nargis, Ghoulem Ifrene, Brent Jeffrey Voels, Colin K. Combs

Biomedical Sciences Posters and Presentations

Cell culture studies routinely seek to monitor cell migration in response to chemoattractant stimuli. Common assays of cell migration employ well inserts and vertical cell migration assessment. This approach does not allow real-time monitoring of cell behavior. To address this need, we sought to develop a horizontal culture platform conducive to time course cell assessment changes in migration, morphology, phenotype etc. Modification of a commercial chamber slide allowed us to quantify cell migration in response to a 20% serum gradient. Based upon this finding, we designed and fabricated a prototype chamber slide for high replicate, real time assessment of cell …

Experiencias De Vida De Madres Con Hijos En Condición De Discapacidad Visual, Luz Yurany Barona Peña, Judy Alexandra Rey León, Juan Fernando Oyasa Moncayo, Sandra Ortiz Vega

Ciencia y Tecnología para la Salud Visual y Ocular

El objetivo del presente estudio es describir las experiencias de vida de madres con hijos en condición de discapacidad visual reportadas en la literatura científica. Se realizó una búsqueda de literatura en idioma inglés, sin límite en el periodo de publicación, por medio de los motores de búsqueda Pubmed, Scopus y Google Scholar. A los resultados reportados en dicha pesquisa se les aplicaron los criterios de inclusión y de exclusión planteados para este trabajo, seguidos de la evaluación de la calidad científica (Caspe), y finalmente se analizó cada uno de los artículos, organizando dichas experiencias con relación a las diferentes …

Ginkgo Biloba Extract 761 Reduces The Risk Of Progression Of Age-Related Macular Degeneration, Sergio Ramírez-González, Elizabeth Casillas-Casillas, Fernando Jaramillo-Juárez, Ana Rosa Rincón-Sánchez

Ciencia y Tecnología para la Salud Visual y Ocular

La degeneración macular relacionada con la edad (AMD) es la principal causa de ceguera. Su desarrollo es poco conocido, pero concentraciones altas de especies reactivas de oxígeno pueden desencadenarla. El objetivo del estudio fue analizar si la acción antioxidante del suplemento dietético ginkgo biloba (EGb-761) retrasa el desarrollo de la AMD. Ensayo clínico hecho en México, con personas mayores de 55 años. Pacientes con AMD recibieron EGb-761: 50 mg/día (n = 26) o 100 mg/día (n = 22), durante 3 meses. Participó un grupo control de 22 personas sanas. Antes y después del tratamiento, se realizaron pruebas oculares funcionales y …