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A Genetically Informed Study Of Acute Threat Endophenotypes For Callous-Unemotional Traits, Ashlee A. Moore 2019 Virginia Commonwealth University

A Genetically Informed Study Of Acute Threat Endophenotypes For Callous-Unemotional Traits, Ashlee A. Moore

Theses and Dissertations

Introduction. Callous-unemotional (CU) traits predict socially debilitating outcomes including Antisocial Personality Disorder and violent crime in adulthood. Despite significant research, the etiology of CU traits is not well understood. This dissertation incorporates genetic, physiological, neuroanatomical, and self-report measures to investigate the etiology of CU traits. Specifically, this project focuses on measures previously found to associate with impaired fear-processing observed in individuals high on CU. Brain morphometry for paralimbic regions of interest (ROIs) and electromyographic facial eyeblink reflex to startle and fear-potentiated startle probes were investigated as potential endophenotypes for CU traits. Methods. Two genetically informative (ages 9-20) twin samples ( …


Behavioral Assessment Of Social Structure And Guest Provisioning Program Participation Of Zoo-Housed Giraffes (Giraffa Camelopardalis) Under Varying Spatial Availability., Fatima Ramis 2019 University of North Florida

Behavioral Assessment Of Social Structure And Guest Provisioning Program Participation Of Zoo-Housed Giraffes (Giraffa Camelopardalis) Under Varying Spatial Availability., Fatima Ramis

UNF Graduate Theses and Dissertations

Close encounters with animals are considered integral for visitors and are trademark components of traditional educational engagement in zoological parks. As capacity for up-close encounters continue to increase with a simultaneous development in the field of animal welfare science, behavioral assessments on the role of common close encounters is timely. Giraffes (Giraffa camelopardalis) visitor feeding programs are established in approximately 57% of institutions accredited by Association of Zoos and Aquariums. Due to successful breeding and capacity building for zoological giraffe populations, this percentage will likely continue to increase. There is a great deal of variation in the environmental …


Genome-Wide Systems Genetics Of Alcohol Consumption And Dependence, Kristin Mignogna 2019 Virginia Commonwealth University

Genome-Wide Systems Genetics Of Alcohol Consumption And Dependence, Kristin Mignogna

Theses and Dissertations

Widely effective treatment for alcohol use disorder is not yet available, because the exact biological mechanisms that underlie this disorder are not completely understood. One way to gain a better understanding of these mechanisms is to examine the genetic frameworks that contribute to the risk for developing this disorder. This dissertation examines genetic association data in combination with gene expression networks in the brain to identify functional groups of genes associated with alcohol consumption and dependence.

The first study took advantage of the behavioral complexity of human samples, and experimental capabilities provided by mouse models, by co-analyzing gene expression networks …


The Role Of Progesterone Receptor In The Developing Medial Preoptic Nucleus, Diana Lalitsasivimol 2019 University at Albany, State University of New York

The Role Of Progesterone Receptor In The Developing Medial Preoptic Nucleus, Diana Lalitsasivimol

Legacy Theses & Dissertations (2009 - 2024)

Numerous neurodevelopmental and neuropsychiatric diseases have a distinct sex bias in


Measuring Glutamate And Oxygen In Brain Reward Circuits In Animal Models Of Cocaine Abuse And Decision-Making, Seth Richard Batten 2019 University of Kentucky

Measuring Glutamate And Oxygen In Brain Reward Circuits In Animal Models Of Cocaine Abuse And Decision-Making, Seth Richard Batten

Theses and Dissertations--Psychology

Drug-specific reward and associated effects on neural signaling are often studied between subjects, where one group self-administers drug and a separate group self-administers a natural reinforcer. However, exposure to drugs of abuse can cause long-term neural adaptations that can affect how an organism responds to drug reward, natural reward, and their reward-associated stimuli. Thus, to isolate drug-specific effects it is important to use models that expose the same organism to all of the aforementioned. Multiple schedules provide a means of dissociating the rewarding effects of a drug from the rewarding effects of food within a single animal. Further, drug users …


Team Member Hormone Profiles And Group Cohesion, David Webster 2019 Wilfrid Laurier University

Team Member Hormone Profiles And Group Cohesion, David Webster

Theses and Dissertations (Comprehensive)

Group cohesion in sport is associated with many positive outcomes for the team as a whole, as well as for the individuals. Hence, it is important to understand the antecedents of cohesion in various contexts, including sport. One antecedent that has yet to be examined in a sports context pertains to biological factors; specifically, the interaction of testosterone and cortisol levels. The dual-hormone hypothesis posits that testosterone levels are associated with status attainment for both individuals and groups, but only amongst those with low cortisol levels. Based on previous literature, a high testosterone-low cortisol hormonal profile should be associated with …


Examining The Utility Of Behavioral Economic Demand In Addiction Science, Justin Charles Strickland 2019 University of Kentucky

Examining The Utility Of Behavioral Economic Demand In Addiction Science, Justin Charles Strickland

Theses and Dissertations--Psychology

The marriage of perspectives from behavioral economic theory and learning theory has the potential to advance an understanding of substance use and substance use disorder. Behavioral economic demand is a central concept to this interdisciplinary approach. Evaluating demand in the laboratory and clinic can improve previous research on the relative reinforcing effects of drugs by accounting for the multi-dimensional nature of reinforcement rather than viewing reinforcement as a unitary construct. Recent advances in the commodity purchase task methodology have further simplified the measurement of demand values in human participants. This dissertation project presents a programmatic series of studies designed to …


Dispositional Empathy And Autonomic Reactivity During A Comfort Interaction, Alaina G. Tiani 2019 West Virginia University

Dispositional Empathy And Autonomic Reactivity During A Comfort Interaction, Alaina G. Tiani

Graduate Theses, Dissertations, and Problem Reports

The purpose of the current study was to examine the association between dispositional (trait) empathy and autonomic reactivity during dyadic interactions among women enrolled in undergraduate psychology courses. The primary research question was: do individuals who are deemed higher in dispositional empathy according to self-report exhibit differential autonomic reactivity patterns during a task in which they are asked to comfort another student experiencing emotional distress than those who are deemed lower in dispositional empathy? The literature on this relation has been mixed and has utilized photos or videos to evoke emotion; thus this study sought to examine the relation between …


The Effects Of Oral Contraceptives On Mood And Affect: A Meta-Analysis, Erica M. Motter 2019 Humboldt State University

The Effects Of Oral Contraceptives On Mood And Affect: A Meta-Analysis, Erica M. Motter

Cal Poly Humboldt theses and projects

Combined oral contraceptive (COC) pills are widely used by women of reproductive age, but there is still little conclusive evidence that exists about the mood-related side effects associated with their use. This meta-analysis examined the relationship between oral contraceptive use and mood effects such as depression and anxiety to determine what role, if any, that COCs may have in the worsening or improvement of women’s mood when taking them. Effect sizes compared the differences in women’s mood scores before taking COCs and after one or more cycles of use. Seventeen studies made up of 25 individual samples contributed 71 effect …


The Effects Of C-Tactile Afferent Stimulation On Male Orgasm And Ejaculation, Yacoub Ayed Innabi 2019 Cal Poly Humboldt

The Effects Of C-Tactile Afferent Stimulation On Male Orgasm And Ejaculation, Yacoub Ayed Innabi

Cal Poly Humboldt theses and projects

Orgasms and ejaculation are important for relationships and contribute significantly to life satisfaction. There is, however, a lack of research in the current literature regarding orgasm perception. This study tested the effects of endogenous oxytocin on subjective orgasm intensity, ejaculation latency, and ejaculate volume in men. At two separate test sessions, the participants were either stroked on the forearm (to release endogenous oxytocin) or tapped on the hand (to act as a control) with a cosmetic brush. The forearm contains C-tactile afferents that are believed to release oxytocin centrally and peripherally in response to slow, soft stroking stimulation. Then a …


Eye Movements For Learned Faces, Mariah Lehnertz 2019 Cal Poly Humboldt

Eye Movements For Learned Faces, Mariah Lehnertz

Cal Poly Humboldt theses and projects

Humans demonstrate a perceptual specialization for faces that is astonishing. This project attempts determine if and where within the perceptual process face perception and face recognition diverge at the level of eye movement behaviors. Participants were exposed to a series of 36 faces, of which six were randomly selected to be learned over five subsequent exposures; thus the same face identities served as both the novel faces (block 1) and the learned faces (block 5), allowing for the measurement of eye gaze patterns during initial face perception (novel) and face recognition (learned). These six faces were randomly assigned to different …


"I See Gay People" Gaydar Abilities In A Real-World Distribution, Benjamin Patrick Skillman 2019 Humboldt State University

"I See Gay People" Gaydar Abilities In A Real-World Distribution, Benjamin Patrick Skillman

Cal Poly Humboldt theses and projects

“Gaydar” is the colloquial term for identifying someone’s sexual orientation from physical cues. Past literature has shown that people can identify someone’s sexual orientation at above chance levels. Past literature has used a 50/50 split of gay and straight faces and used non-standardized images, which can induce confounds in the results. The present study examined gaydar accuracy in a realistic distribution of straight and gay faces using standardized images and examined facial morphology for differences between gay and straight men. Participants were not found to have above chance accuracy for identifying gay faces. PCA did not identify reliable shape differences …


Untangling The Reciprocal Relation Of The Behavioral And Physiological Immune Systems, Baris Sevi 2019 West Virginia University

Untangling The Reciprocal Relation Of The Behavioral And Physiological Immune Systems, Baris Sevi

Graduate Theses, Dissertations, and Problem Reports

In the past decade, there has been an exponential increase in the study of the Behavioral Immune System (BIS), a suite of psychological processes that serves an infectious disease avoidance function. The BIS is proposed to be inherently intertwined with the physiological immune system. However, very few studies have actually demonstrated this fundamental, theoretical assumption. The purpose of this thesis was to test the possible relation between the physiological and behavioral immune systems in two studies. In Study 1 (N = 388), the relation between implied activation of the physiological immune system and BIS sensitivity was examined. Participants who reported …


Stress, Social Support, And Mindfulness In Parents Of Children With Neurodevelopmental Deficits: A Quantitative Analysis, Branden D. Syrotchen 2019 Walden University

Stress, Social Support, And Mindfulness In Parents Of Children With Neurodevelopmental Deficits: A Quantitative Analysis, Branden D. Syrotchen

Walden Dissertations and Doctoral Studies

Parenting children with neurodevelopmental deficits (NDDs) is very stressful, more so than the parenting of typically developing children. There is considerable research on the topic of chronic stress experienced by caregivers; however, less is understood of parental stress experienced when raising children with NDDs. The purpose of this study was to examine how parental traits and habits, in the forms of mindfulness and social support levels, affect this cohort's general stress levels. The study was guided by Self-Determination Theory, which explored how parental acts could be classified along a continuum of being intrinsically or extrinsically derived. A convenience sample of …


Short-Term Abstinence Effects In Experienced Electronic Cigarette Users, Nicholas J. Felicione 2019 West Virginia University

Short-Term Abstinence Effects In Experienced Electronic Cigarette Users, Nicholas J. Felicione

Graduate Theses, Dissertations, and Problem Reports

Nicotine/tobacco dependence is a problem that negatively affects health at an individual and population level. Nicotine/tobacco dependence may be best assessed by measuring withdrawal symptoms of a nicotine/tobacco user who abstains from use. Withdrawal symptoms experienced by cigarette smokers are well characterized, including deficits in attention and memory, as well as self-reported cravings, urges, and other symptoms. While withdrawal in cigarette smokers has been studied extensively, little is known about dependence and withdrawal associated with newer products, such as electronic cigarettes (ECIGs). ECIGs can deliver nicotine comparably to tobacco cigarettes, indicating that they may have the potential to cause dependence. …


Portion Size Influences Intake In Samburu Kenyan People Not Exposed To The Western Obesogenic Environment, Kevin P. Myers, Jeffrey M. Brunstrom, Peter J. Rogers, Jon D. Holtzman 2019 Bucknell University

Portion Size Influences Intake In Samburu Kenyan People Not Exposed To The Western Obesogenic Environment, Kevin P. Myers, Jeffrey M. Brunstrom, Peter J. Rogers, Jon D. Holtzman

Faculty Journal Articles

For people in the modernized food environment, external factors like food variety, palatability, and ubiquitous learned cues for food availability can overcome internal, homeostatic signals to promote excess intake. Portion size is one such external cue; people typically consume more when served more, often without awareness. Though susceptibility to external cues may be attributed to the modernized, cue-saturated environment, there is little research on people living outside that context, or with distinctly different food norms. We studied a sample of Samburu people in rural Kenya who maintain a traditional, semi-nomadic pastoralist lifestyle, eat a very limited diet, and face …


The Influence Of Depressive Symptoms On Frn Amplitude: An Eeg Study, Jonathan Burton 2018 University of South Carolina - Aiken

The Influence Of Depressive Symptoms On Frn Amplitude: An Eeg Study, Jonathan Burton

USC Aiken Psychology Theses

Background: Individuals diagnosed with depression demonstrate differences in neural activation patterns detectable using electroencephalogram (EEG). One of these differences has been specifically linked with the event-related potential (ERP) component called feedback-related negativity (FRN). In participants diagnosed with depression, the FRN has been shown to have larger amplitudes in response to negative feedback. However, previous research has only specifically looked at the difference of this amplitude between groups, specifically those with and those without a diagnosis of depression. Objective: The goal of the current study was to examine whether a continuous range of depressive symptoms in participants can predict FRN amplitudes, …


Diurnally Active Rodents For Laboratory Research, Roberto Refinetti, G. J. Kenagy 2018 Boise State University

Diurnally Active Rodents For Laboratory Research, Roberto Refinetti, G. J. Kenagy

Psychological Sciences Faculty Publications and Presentations

Although inbred domesticated strains of rats and mice serve as traditional mammalian animal models in biomedical research, the nocturnal habits of these rodents make them inappropriate for research that requires a model with human-like diurnal activity rhythms. We conducted a literature review and recorded locomotor activity data from four rodent species that are generally considered to be diurnally active, the Mongolian gerbil (Meriones unguiculatus), the degu (Octodon degus), the African (Nile) grass rat (Arvicanthis niloticus), and the antelope ground squirrel (Ammospermophilus leucurus). Our data collected under 12L:12D light-dark cycles confirmed and expanded …


Exercise Engagement And Longitudinal Change In Alzheimer's Disease Biomarkers, Regional Brain Structure, And Cognitive Functioning, Marta Stojanovic 2018 Washington University in St. Louis

Exercise Engagement And Longitudinal Change In Alzheimer's Disease Biomarkers, Regional Brain Structure, And Cognitive Functioning, Marta Stojanovic

Arts & Sciences Electronic Theses and Dissertations

No abstract provided.


Effects Of Naltrexone On Alcohol And Nicotine Use In Female P Rats, Usman Z. Hamid, Michael T. Bardo Ph.D. 2018 University of Kentucky

Effects Of Naltrexone On Alcohol And Nicotine Use In Female P Rats, Usman Z. Hamid, Michael T. Bardo Ph.D.

Posters-at-the-Capitol

Title: Effects of Naltrexone on Alcohol and Nicotine Use in Female P Rats

Author: Usman Z. Hamid, Department of Psychology, University of Kentucky

Faculty Mentor: Michael T. Bardo, Ph.D., Department of Psychology, University of Kentucky

Alcohol is the most commonly abused substance worldwide. It is often co-abused with nicotine, which increases the difficulty of cessation of both alcohol and nicotine. Despite having similar mechanisms of action, there is no single medication to treat the co-abuse. The objective of the current study is to analyze the effects of the opiate antagonist naltrexone on alcohol consumption and the co-use of alcohol and …


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