Virus Diseases Commons^™

Ua94/6/1 My Story: Wku Baseball's Kevin Lambert, Kevin Lambert

Student/Alumni Personal Papers

My Story is a series of first-person feature articles written by WKU student-athletes. The student-athletes will be telling their own stories in their own words. This article written by baseball senior shortstop Kevin Lambert, whose season came to a sudden end as the team was heading to Birmingham, Alabama for its first conference series of the year.

Characterization Of A Plasmid-Based Dna Vaccine For Simian Immunodeficiency Virus, Priya Sanipara

Honors Theses

Described as one of the world’s worst pandemics, HIV (Human Immunodeficiency Virus) infects millions of people each year and is the cause for AIDS (Acquired Immunodeficiency Syndrome). Despite the development of vaccines for numerous infectious diseases such as polio, small pox, and influenza, a vaccine for HIV remains elusive due to the virus’s high mutation rate and ability to evade the immune system. HIV causes depletion of CD4+ lymphocytes, resulting in a weakened immune system. However, the development of a plasmid-based DNA vaccine approach may help revolutionize vaccine development for HIV due to its ability to confer cellular and humoral …

Coronavirus Update 5-8-20, The Coronavirus Planning Team

University Briefings & Virtual Events

Connecticut Governor Ned Lamont came out with guidance for reopening colleges and universities. The good news is that the recommendations are in line with the discussions and planning that are already taking place among Sacred Heart’s task forces that are preparing for the fall semester and beyond in the wake of the coronavirus.

The Wedge, Jonathan Knippenberg

Reflections, Poetry, Photos, and other Writings

This poem is fueled by the emotions of a senior year cut short and living at home again.

Professor Susan Goncalves Donates Plasma To Covid-19 Patients, Sacred Heart University

University Briefings & Virtual Events

Susan Goncalves, a professor in Sacred Heart University's Dr. Susan L. Davis, RN, & Richard Henley College of Nursing, has been a nurse at St. Vincent's Medical Center in Bridgeport for 35 years. On March 23, when she began experiencing chills due to a fever, she knew she needed to be tested. Three days later, her results came in COVID-19 positive.

The Neurology Of Covid-19 Revisited: A Proposal From The Environmental Neurology Specialty Group Of The World Federation Of Neurology To Implement International Neurological Registries, Gustavo C. Román, Peter S. Spencer, Jacques Reis, Alain Buguet, Mostafa El Alaoui Faris, Sarosh M. Katrak, Miguel Láinez, Marco Tulio Medina, Chandrashekhar Meshram, Mohammad Wasay

Section of Neurology

A comprehensive review of the neurological disorders reported during the current COVID-19 pandemic demonstrates that infection with SARS-CoV-2 affects the central nervous system (CNS), the peripheral nervous system (PNS) and the muscle. CNS manifestations include: headache and decreased responsiveness considered initial indicators of potential neurological involvement; anosmia, hyposmia, hypogeusia, and dysgeusia are frequent early symptoms of coronavirus infection. Respiratory failure, the lethal manifestation of COVID-19, responsible for 264,679 deaths worldwide, is probably neurogenic in origin and may result from the viral invasion of cranial nerve I, progressing into rhinencephalon and brainstem respiratory centers. Cerebrovascular disease, in particular large-vessel ischemic strokes, …

Ua94/6/1 My Story: Wku Womens Basketball's Whitney Creech, Whitney Creech

Student/Alumni Personal Papers

My Story is a series of first-person feature articles written by WKU student-athletes. The student-athletes will be telling their own stories in their own words. This article written by women’s basketball senior Whitney Creech, who was in her senior season on The Hill when the Covid-19 pandemic caused the cancellation of the Conference USA Tournament in Frisco, Texas.

How Misinformation And Mistrust Compound The Threat Of Epidemics, William Boyd

Honors Theses

This thesis was conducted to study the effects of misinformation and medical mistrust on the public health field. I use the events of the Chapare Virus outbreak in Bolivia in the summer of 2019 and the public dialogue during that time period to discuss these themes. I used data from market survey's in La Paz, newspaper articles from Página Siete, and Tweets from the time period of the outbreak. My findings suggest that misinformation and medical mistrust affected public health measures, which has major implications for the way the public health field should address future public health events.

U.S. Response To Covid-19 Compared To Other Diseases, Brian E. Barton

2020 Symposium Posters

Emergence of a new infectious disease out of China has caused a global reaction to combat the spread. On December 31, 2019, China reported a cluster of cases of pneumonia in people associated with the Huanan Seafood Wholesale Market in Wuhan, Hubei Province. On January 7, 2020, Chinese health authorities confirmed that this cluster was associated with a novel coronavirus, 2019-nCoV. Governments around the world responded to the threat by instituting lockdowns, closing businesses, using experimental medications, and even closing boarders. Citizens responded in kind by increasing social distancing and the usage of personal protective devices such as face masks …

Separation Anxiety, Nisha Sidana

Community Reflections

I wrote this poem about a month and a half after we were sent home from SHU. A couple of my friends were talking to me one day, telling me how much they missed their boyfriends/girlfriends, everything they love about them, and their longing to see them, knowing they wouldn't be able to. I took inspiration from this, as well as the feeling of being suddenly separated from the people you love, and wrote it into a poem I titled "Separation Anxiety." I wanted to artistically express the feeling a person gets when they realize how much they have taken …

Pneumonia: An Unexpected Graveyard Visitor?, Daniel A. Casas, Jigar Chauhan, Melanie Williams, Jan Sambataro, David Sukhai, Pablo G. Dubon, Jorge Perez

West Florida Division GME Research Day 2020

Community acquired pneumonia caused by Influenza can present with superinfection. On rare occasions, an unexpected organism is discovered.

My Thoughts On Covid-19, Patrick Ferraro

Community Reflections

I feel deeply sorry for the loved ones that were lost from the SHU community directly from COVID-19. The tragedy of death can feel even worse in a time like this where it’s almost as if we can feel it through all of the fear we are presented with.

Coronavirus Update 5-1-2020, The Coronavirus Planning Team

University Briefings & Virtual Events

Our plan to offer a full on-campus program for both residential and commuter students (for the fall semeser) will not come without temporary changes to our typical way of campus life.

Experience During Covid-19, Anonymous

Community Reflections

This submission from Professor James Bartley was a class assignment from a student who maintained a journal describing her experience working at a hospital during the pandemic.

Gut Pathophysiology In Mouse Models Of Social Behavior Deficits, Kyla Scott

Undergraduate Honors Theses

Autism spectrum disorders (ASD) encompass neurodevelopment disorders characterized by atypical patterns of development that impact multiple areas of functioning beginning in early childhood. The etiology of ASD is unknown and there are currently no preventative treatment options. Gastrointestinal symptoms are commonly associated comorbidities. The microbiota-gut-brain axis is a multidirectional communication chain that connects the central and enteric nervous system that relates brain function to peripheral intestinal functions. Changes within this axis have been postulated in ASD. For example, the “leaky gut theory” proposes that chronic inflammation is linked to alterations in the bacterial profiles of the gut microbiome and subsequent …

Development Of Rationally Designed Live Attenuated Vaccines For Lassa Fever And Venezuelan Equine Encephalitis., Dylan Macgregor Johnson

Electronic Theses and Dissertations

Lassa Virus (LASV) and Venezuelan Equine Encephalitis Virus (VEEV) are two single stranded RNA viruses belonging to the Arenavirus and Alphavirus families, respectively. Both are emerging pathogens without approved vaccines or treatments. VEEV is an important biothreat pathogen because it has been weaponized and is extremely infectious as an aerosol. VEEV causes biphasic febrile illness that can progress to a viral encephalitis with low mortality, but high morbidity. LASV causes a viral hemorrhagic fever, Lassa Fever (LF), which is endemic in West Africa, and responsible for between 100-500k annual infections with a 1-2% overall mortality rate. ML29 and VEEV TC-83 …

Effect Of Cigarette Smoking On Cd4 Count And Viral Load Among Hiv Patients Attending Treatment At Nebraska Medicine, Chacha Josiah Mwita

Capstone Experience: Master of Public Health

Background

Smoking is known to have a negative impact on both morbidity and mortality in people living with HIV (PLHIV). However, there is inconsistent information about the role of smoking on markers of HIV disease progression (CD4 count and HIV viral load). This study examined the effects of cigarette smoking on markers of HIV disease progression among PLHIV at Nebraska Medicine.

Methods

A retrospective cohort study was conducted utilizing electronic health information of 604 PLHIV who attended treatment at Nebraska Medicine between 2012 and 2020. Multiple linear regression was used to model the effects of smoking on the mean change …

How Nutrition Can Help To Fight Against Covid-19 Pandemic, Faseeha Aman, Sadia Masood

Section of Internal Medicine

Currently Covid-19 pandemic is a leading challenge across the globe. It is mandatory to attain and maintain good nutritional status to fight against virus. Nutritional status of individual is affected by several factors such as age, sex, health status, life style and medications. Nutritional status of individuals has been used as resilience towards destabilization during this COVID-19 pandemic. Optimal nutrition and dietary nutrient intake impact the immune system, therefore the only sustainable way to survive in current context is to strengthen the immune system. There is no evidence found that supplement can cure the immune system except Vit C, which …

Variability In State Regulations Pertaining To Infection Control And Pandemic Response In Us Assisted Living Communities, Taylor Bucy, Lindsey Smith, Paula C. Carder, Jaclyn Winfree, Kali Thomas

OHSU-PSU School of Public Health Faculty Publications and Presentations

At the end of 2019, international attention was drawn to an outbreak of zoonotic coronavirus SARS-CoV-2, formally named COVID-19, in Wuhan, China. The World Health Organization officially declared the outbreak a global pandemic on March 11, 2020, with the United States recording >1600 confirmed and presumptive travel-related and community-acquired cases at that time. As of April 10, 2020, all 50 US states and the District of Columbia, have reported cases, with the total number of US cases now totaling >400,000.2 Seattle, WA, is the US epicenter, with nursing facilities experiencing the greatest number of fatalities. Because of the communal living …

Investigating The Interactions Between Individual Calmodulin And Hiv-1 Protein Domains, Riley K. Kendall, Jerry Larue

Student Scholar Symposium Abstracts and Posters

The World Health Organization found that 37.9 million people were living with HIV by the end of 2018. HIV is a virus that weakens the immune system through viral replication and the destruction of CD4⁺ T-cells, which are white blood cells that detect infection and make antibodies. A cure for HIV has not yet been discovered. HIV-1 contains a Gag polyprotein which regulates the stages of viral replication. Previous studies suggest that the myristoyl group of a matrix protein peptide found on the Gag polyprotein, MA, forms a complex with a calcium-binding, multifunctional regulatory protein called Calmodulin (CaM). CaM …