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Reduction Of Secondary Transmission Of Sars-Cov-2 In Households By Face Mask Use, Disinfection And Social Distancing: A Cohort Study In Beijing, China, Yu Wang, Huaiyu Tian, Li Zhang, Dandan Guo, Wenting Wu, Xingxing Zhang, Ge Lin Kan, Lei Jia, Da Huo, Beiwei Liu, Xiaoli Wang, Ying Sun, Quanyi Wang, Peng Yang, C. Raina MacIntyre 2020 Beijing Research Center for Preventive Medicine

Reduction Of Secondary Transmission Of Sars-Cov-2 In Households By Face Mask Use, Disinfection And Social Distancing: A Cohort Study In Beijing, China, Yu Wang, Huaiyu Tian, Li Zhang, Dandan Guo, Wenting Wu, Xingxing Zhang, Ge Lin Kan, Lei Jia, Da Huo, Beiwei Liu, Xiaoli Wang, Ying Sun, Quanyi Wang, Peng Yang, C. Raina Macintyre

Environmental & Global Health Faculty Research

Introduction Transmission of COVID-19 within families and close contacts accounts for the majority of epidemic growth. Community mask wearing, hand washing and social distancing are thought to be effective but there is little evidence to inform or support community members on COVID-19 risk reduction within families. Methods: A retrospective cohort study of 335 people in 124 families and with at least one laboratory confirmed COVID-19 case was conducted from 28 February to 27 March 2020, in Beijing, China. The outcome of interest was secondary transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) within the family. Characteristics and practices of …


Ua94/6/1 My Story: Wku Basketball's Kenny Cooper, Kenny Cooper 2020 Western Kentucky University

Ua94/6/1 My Story: Wku Basketball's Kenny Cooper, Kenny Cooper

Student/Alumni Personal Papers

My Story is a series of first-person feature articles written by WKU student-athletes. The student-athletes will be telling their own stories in their own words. This article written by basketball senior guard Kenny Cooper, who redshirted as a transfer in 2019-20 but will play his final college season this upcoming year.


Managing Acute Pain In Hiv+/Aids Patients: Knowledge And Practice Trends Among Emergency Physicians Of Major Tertiary Care Centers Of A Developing Country, Aliya Ahmed, Gauhar Afshan, Robyna Irshad Khan, Badar Afzal Khan, Seemin Jamali, Nighat Farooq, Sarosh Saleem, Rubaba Naeem, Uzma R. Khan 2020 Aga Khan University

Managing Acute Pain In Hiv+/Aids Patients: Knowledge And Practice Trends Among Emergency Physicians Of Major Tertiary Care Centers Of A Developing Country, Aliya Ahmed, Gauhar Afshan, Robyna Irshad Khan, Badar Afzal Khan, Seemin Jamali, Nighat Farooq, Sarosh Saleem, Rubaba Naeem, Uzma R. Khan

Department of Anaesthesia

Objective: To assess knowledge and practice trends in managing acute pain in patients infected with human immunodeficiency virus (HIV+) or having acquired immunodeficiency syndrome (AIDS) among emergency physicians of four tertiary care hospitals. Acute pain management in such patients is complex because of multiple concomitant painful conditions related to their disease. After obtaining ethical approval and written informed consent, emergency physicians were requested to fill out a questionnaire.
Results: Out of 84 physicians who participated, 49 had managed HIV+/AIDS patients during the preceding year. Out of the 49, 30 (61.2%) physicians stated that they used a combination of analgesics for …


Combined Effects Of Gender Affirmation And Economic Hardship On Vulnerability To Hiv: A Qualitative Analysis Among U.S. Adult Transgender Women., Larissa Jennings Mayo-Wilson, Eric G. Benotsch, Sheila R. Grigsby, Sarah Wagner, Fatmata Timbo, Tonia Poteat, Lauretta Cathers, Ashlee N. Sawyer, Shelby A. Smout, Rick S. Zimmerman 2020 Indiana University

Combined Effects Of Gender Affirmation And Economic Hardship On Vulnerability To Hiv: A Qualitative Analysis Among U.S. Adult Transgender Women., Larissa Jennings Mayo-Wilson, Eric G. Benotsch, Sheila R. Grigsby, Sarah Wagner, Fatmata Timbo, Tonia Poteat, Lauretta Cathers, Ashlee N. Sawyer, Shelby A. Smout, Rick S. Zimmerman

School of Nursing Faculty Publications

Background: Transgender women ("trans women"), particularly African-American and Latina trans women, have disproportionately high prevalence of HIV in the United States (U.S.). In order to decrease gender dysphoria and overcome discrimination, trans women affirm their gender through social and medical transition, often in contexts of economic hardship and sexual risk. This study qualitatively examined how gender-affirming behaviors enhance or diminish vulnerability to HIV in light of structural and economic barriers to gender transition.Methods: We conducted individual interviews with 19 adult trans women in two U.S. cities (Richmond, VA and St. Louis, MO) who reported one or more sexual risk behaviors …


Faqs For Administrators And Leaders At Community- And Faith-Based Organizations, Centers for Disease Control and Prevention 2020 Western Michigan University

Faqs For Administrators And Leaders At Community- And Faith-Based Organizations, Centers For Disease Control And Prevention

Pandemic Response and Religion in the USA: Health

This is the Frequently Asked Questions webpage from the Centers for Disease Control and Prevention designed to help places of worship prevent the spread of COVID-19 in their congregations. The FAQ page includes prevention strategies, community outreach strategies, and how to decide if services should be in person or virtual. Issues such as discrimination and marginalized populations are discussed on the FAQ page.


Community And Faith-Based Organizations: Plan, Prepare, And Respond, Centers for Disease Control and Prevention 2020 Western Michigan University

Community And Faith-Based Organizations: Plan, Prepare, And Respond, Centers For Disease Control And Prevention

Pandemic Response and Religion in the USA: Law and Public Policy

No abstract provided.


Interim Guidance For Communities Of Faith, Centers for Disease Control and Prevention 2020 Western Michigan University

Interim Guidance For Communities Of Faith, Centers For Disease Control And Prevention

Pandemic Response and Religion in the USA: Health

This article from the CDC offers guidelines for religious groups and organizations that are beginning to reopen and hold in-person services as stay-at-home orders are lifted. Guidelines include hygiene tips, disinfecting practices, the use of face masks, and other safe practices designed to keep houses of worship safe as they reopen. Other guidelines include policies for houses of worship to put in place for their congregants upon reopening, such as the use of worship materials.


Coronavirus Update 5-22-2020, The Coronavirus Planning Team 2020 Sacred Heart University

Coronavirus Update 5-22-2020, The Coronavirus Planning Team

University Briefings & Virtual Events

Last weekend, we gave you a broad overview of the SHU-Flex model and the University’s plans and protocols for on-campus, face-to-face learning in the fall. Our plans must be consistent with the guidelines set forth by the State of CT and the CDC, which continue to evolve. Since last week’s message, we have received several questions from you that we will address below. We thank you for your continued patience. In an ideal world, we would not be making any changes at all, but we must adapt our usual way of functioning to maximize the health and safety of the …


Ua94/6/1 My Story: Wku Football's Malik Staples, Malik Staples 2020 Western Kentucky University

Ua94/6/1 My Story: Wku Football's Malik Staples, Malik Staples

Student/Alumni Personal Papers

My Story is a series of first-person feature articles written by WKU student-athletes. The student-athletes will be telling their own stories in their own words. This article written by football graduate senior Malik Staples, who – along with his teammates – has navigated through a different type of Spring Ball over the past two months.


Pandemic 2020 In Myndsight, Shawn D. Denny 2020 Taylor University - Upland

Pandemic 2020 In Myndsight, Shawn D. Denny

Reflections, Poetry, Photos, and other Writings

A poem, or rhapsodic reflection if you like, on the experience of being isolated due to the stay-at-home restrictions invoked by the pandemic. As my context is largely influenced by my involvement as a faculty and community member of Taylor University, the thoughts encapsulated also reflect that context.


Efficacy Of Convalescent Plasma And Short Course Of Corticosteroids In Patients With Covid-19, Srikanth Ramachandruni, Po-Yang Tsou, D.C. Benetez, Gayathri Evani, Smitha Gudipati, Ramakrishna Chakilam, Polly Mock, Bharat Narasimhan, Dhanunjay Lakkireddy, Shekhar Raj 2020 CHRISTUS Spohn Health System

Efficacy Of Convalescent Plasma And Short Course Of Corticosteroids In Patients With Covid-19, Srikanth Ramachandruni, Po-Yang Tsou, D.C. Benetez, Gayathri Evani, Smitha Gudipati, Ramakrishna Chakilam, Polly Mock, Bharat Narasimhan, Dhanunjay Lakkireddy, Shekhar Raj

The University of Louisville Journal of Respiratory Infections

This study reported the efficacy of short-course corticosteroids and convalescent plasma (CP) transfusion in treating five patients with severe COVID-19 disease. Five adults (mean±standard deviation age: 70±9 years) with laboratory-confirmed COVID-19 and severe hypoxemia (PaO2/FiO2 [P/F]<100) requiring invasive mechanical ventilation received five days methylprednisolone (40 mg intravenously every 12 hours) and subsequent CP transfusion (250–400 ml). Compared with the baseline, P/F ratios increased by 46% and by 28% after short course corticosteroids and CP transfusion, respectively. Four patients survived. Short-course corticosteroids and CP transfusion may improve hypoxemia in patients with severe COVID-19 disease.


A Role For Retinoids In The Treatment Of Covid-19?, Steven E. Trasino 2020 CUNY Hunter College

A Role For Retinoids In The Treatment Of Covid-19?, Steven E. Trasino

Publications and Research

The 2020 global outbreak of the novel coronavirus (SARS-CoV-2 or COVID-19) is a serious threat to international health, and thus, there is an urgent need for discoverynof novel therapies or use of repurposed drugs that can make a significant impact on slowing the spread of the virus. Type 1 interferons (IFN-I) are a family cytokines of the early innate immune response to viruses that are being tested against SARSCoV- 2. However, coronaviruses similar to SARS-CoV-2 can suppress host IFN-I antiviral responses. Retinoids are a family molecules related to vitamin A that possess robust immune-modulating properties, including the ability to increase …


The Last Mile, Michael Hammond 2020 Taylor University

The Last Mile, Michael Hammond

Reflections, Poetry, Photos, and other Writings

My desire was to encourage the community as we head into Finals Week.


Comparative Antiviral Activity Of Remdesivir And Anti-Hiv Nucleoside Analogs Against Human Coronavirus 229e (Hcov-229e), Keykavous Parang, Naglaa Salem El-Sayed, Assad J. Kazeminy, Rakesh Tiwari 2020 Chapman University

Comparative Antiviral Activity Of Remdesivir And Anti-Hiv Nucleoside Analogs Against Human Coronavirus 229e (Hcov-229e), Keykavous Parang, Naglaa Salem El-Sayed, Assad J. Kazeminy, Rakesh Tiwari

Pharmacy Faculty Articles and Research

Remdesivir is a nucleotide prodrug that is currently undergoing extensive clinical trials for the treatment of COVID-19. The prodrug is metabolized to its active triphosphate form and interferes with the action of RNA-dependent RNA polymerase of SARS-COV-2. Herein, we report the antiviral activity of remdesivir against human coronavirus 229E (HCoV-229E) compared to known anti-HIV agents. These agents included tenofovir (TFV), 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA), alovudine (FLT), lamivudine (3TC), and emtricitabine (FTC), known as nucleoside reverse-transcriptase inhibitors (NRTIs), and a number of 5′-O-fatty acylated anti-HIV nucleoside conjugates. The anti-HIV nucleosides interfere with HIV RNA-dependent DNA polymerase and/or act as chain terminators. …


The Covid-19 Pandemic And The Power Of Numbers, Jessica Ancker 2020 Weill Cornell Medical College

The Covid-19 Pandemic And The Power Of Numbers, Jessica Ancker

Numeracy

The COVID-19 pandemic has produced a deluge of news coverage of quantitative concepts. In this viewpoint, we provide examples of effective and poor quantitative communication by the professional news media as well as social media communicators. Effective examples include a number of online animations and engaging interactive simulations. Examples of poor quantitative communication include the widespread reporting of raw numbers rather than rates, failing to address uncertainty, not providing sufficient context for numbers, and not discussing the implications of false negative and false positive diagnostic test results. Educators can draw from this body of news to develop compelling quantitative literacy …


Impact Of Increasing Hpv Vaccination Coverage On Preventing Oropharyngeal Cancer: A Cost-Effectiveness Study, Abhishek Choudhary Dr. 2020 Harvard University

Impact Of Increasing Hpv Vaccination Coverage On Preventing Oropharyngeal Cancer: A Cost-Effectiveness Study, Abhishek Choudhary Dr.

Biology and Medicine Through Mathematics Conference

No abstract provided.


Coronavirus Update 5-15-20, The Coronavirus Planning Team 2020 Sacred Heart University

Coronavirus Update 5-15-20, The Coronavirus Planning Team

University Briefings & Virtual Events

This week we want to provide some more information about the University’s planning for the coming semester. There are many details still to be finalized, but we want to give you as much information as we can to help you with your planning. As you might expect, Sacred Heart is following the guidelines recently provided by the governor for the reopening of universities as well as guidance from health experts.


Ua94/6/1 My Story: Wku Baseball's Kevin Lambert, Kevin Lambert 2020 Western Kentucky University

Ua94/6/1 My Story: Wku Baseball's Kevin Lambert, Kevin Lambert

Student/Alumni Personal Papers

My Story is a series of first-person feature articles written by WKU student-athletes. The student-athletes will be telling their own stories in their own words. This article written by baseball senior shortstop Kevin Lambert, whose season came to a sudden end as the team was heading to Birmingham, Alabama for its first conference series of the year.


Characterization Of A Plasmid-Based Dna Vaccine For Simian Immunodeficiency Virus, Priya Sanipara 2020 University of Mississippi

Characterization Of A Plasmid-Based Dna Vaccine For Simian Immunodeficiency Virus, Priya Sanipara

Honors Theses

Described as one of the world’s worst pandemics, HIV (Human Immunodeficiency Virus) infects millions of people each year and is the cause for AIDS (Acquired Immunodeficiency Syndrome). Despite the development of vaccines for numerous infectious diseases such as polio, small pox, and influenza, a vaccine for HIV remains elusive due to the virus’s high mutation rate and ability to evade the immune system. HIV causes depletion of CD4+ lymphocytes, resulting in a weakened immune system. However, the development of a plasmid-based DNA vaccine approach may help revolutionize vaccine development for HIV due to its ability to confer cellular and humoral …


Coronavirus Update 5-8-20, The Coronavirus Planning Team 2020 Sacred Heart University

Coronavirus Update 5-8-20, The Coronavirus Planning Team

University Briefings & Virtual Events

Connecticut Governor Ned Lamont came out with guidance for reopening colleges and universities. The good news is that the recommendations are in line with the discussions and planning that are already taking place among Sacred Heart’s task forces that are preparing for the fall semester and beyond in the wake of the coronavirus.


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