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Full-Text Articles in Life Sciences

Joint Associations Of Meditation And Physical Activity With Depression And Anxiety Symptoms In Us Adults: Nhis 2022, Yubing Wang Jan 2026

Joint Associations Of Meditation And Physical Activity With Depression And Anxiety Symptoms In Us Adults: Nhis 2022, Yubing Wang

Human Movement Studies & Special Education Faculty Publications

Objectives

Physical activity and meditation may each relate to mental health, but their joint associations in U.S. adults are unclear. We examined the separate and joint associations of any past-year meditation and meeting physical activity (PA) guidelines with depression and anxiety symptoms.

Method

We analyzed data from the 2022 National Health Interview Survey Sample Adult file (n = 24,927). Exposures were meeting PA guidelines, any past-year meditation, and their four-level combination (Neither, PA only, Meditation only, Both). Outcomes were moderate-to-severe depressive and anxiety symptoms (PHQ-8/GAD-7 >= 10). Survey-weighted modified Poisson models estimated prevalence ratios (PRs), with interaction, sensitivity, and post …


Integrating Self-Determination Theory And Continuous Glucose Monitoring: Promoting Youth Development Among Campers With Type 1 Diabetes, Eddie Hill, Bethany Arrington, Taylor Harvey, Alexis Barmoh, Rowan Williams, Laura Hill Jan 2026

Integrating Self-Determination Theory And Continuous Glucose Monitoring: Promoting Youth Development Among Campers With Type 1 Diabetes, Eddie Hill, Bethany Arrington, Taylor Harvey, Alexis Barmoh, Rowan Williams, Laura Hill

Human Movement Studies & Special Education Faculty Publications

The purpose of this cohort study was to evaluate participants’ general self-management and experiences of autonomy while attending diabetes camp using quantitative and qualitative data collection. Through a partnership, an outdoor diabetes camp was designed to assist youth with type 1 diabetes (T1D) in their management. The REACH Teen program conducted a week-long summer camp for youth with T1D. The study was designed through Outcome-Focused Programming grounded in Self-Determination Theory (SDT) to meet campers’ needs of autonomy, competence, and relatedness. Campers participated in outdoor activities and diabetes education designed to increase healthy behaviors. Twenty-three campers completed a 24-item pre- and …


The Effects Of Physical Activity Timing And Adherence To Physical Activity Guidelines On Sleep In Children With Adhd, Xiao Liang, Mengping Zhao, Li Su, Justin A. Haegele, Richard H. Xu, Jingjing Li, Andy Choi-Yeung Tse, Shirley X. Li Jan 2026

The Effects Of Physical Activity Timing And Adherence To Physical Activity Guidelines On Sleep In Children With Adhd, Xiao Liang, Mengping Zhao, Li Su, Justin A. Haegele, Richard H. Xu, Jingjing Li, Andy Choi-Yeung Tse, Shirley X. Li

Human Movement Studies & Special Education Faculty Publications

Regular physical activity (PA) has been shown to benefit sleep. However, the effects of PA timing and adherence to the WHO's recommended 60-min moderate-to-vigorous physical activity (MVPA) guideline on sleep are unclear, especially for children with ADHD who often experience sleep problems. This study examined whether timing of MVPA influenced objectively measured sleep, including sleep latency (SL), sleep efficiency (SE), total sleep time (TST), and wake after sleep onset (WASO), among children with ADHD. This cross-sectional study involved 253 children with ADHD (Mage = 8.60 ± 1.31 years, 81% boys). MVPA timing was categorized as more than 8 h before …


Exploring The Relationships Between Social Influence, Vaping Behaviors, And Susceptibility Across Grade Levels In Kentucky, Raphael Adesiyan, Odunayo O. Omotilewa, Saber Feizy, Melinda J. Ickes Jan 2026

Exploring The Relationships Between Social Influence, Vaping Behaviors, And Susceptibility Across Grade Levels In Kentucky, Raphael Adesiyan, Odunayo O. Omotilewa, Saber Feizy, Melinda J. Ickes

Kinesiology and Health Promotion Faculty Publications

Purpose: This study explored the relationships between social influence, vaping behavior, and susceptibility across different grade levels.   Design: The study design was cross-sectional. Data were collected from middle and high school students who voluntarily participated between September 2022 and April 2023.   Sample: A convenience sample of students in 6th to 12th grades in Kentucky (N = 4677).   Measures: Demographic information, including age, grade level, school location, and race/ethnicity, was collected. The outcome variables included social influence, susceptibility, and vaping behavior.   Analysis: Logistic regression analysis was used to explore the relationships between social influence, vaping behavior, and susceptibility.   Results: …


Chinese Athletes’ And Parents’ Motivations For U.S. Collegiate Sports Participation, Wenting Sun, Russell D. Ravert, Simran Kaur Sethi Jan 2026

Chinese Athletes’ And Parents’ Motivations For U.S. Collegiate Sports Participation, Wenting Sun, Russell D. Ravert, Simran Kaur Sethi

Kinesiology and Health Promotion Faculty Publications

To gain an understanding of international student recruitment and retention in collegiate athletics, this study examines the motivations and decision-making processes of Chinese high school athletes and their parents in pursuing U.S. collegiate sport opportunities. Using the push–pull framework and an ecological perspective, it explores how individual aspirations, family priorities, institutional resources, and national policies shape transnational mobility. Semistructured focus group discussions with 10 athletes and eight parents revealed six key motivational themes and highlighted the influence of recent collegiate sport-related policy changes in China. The findings suggest that while both groups value U.S. sport pathways, athletes and parents may …


Use Of Enterococcus Faecalis And Cetylpyridinium Chloride In Altering Canine Mouth Microbiome, Quigley D. Espinola, Scarlet Renner, Curtis Cline, Sofia Lopez-Orenday, Alex Yasumatsu Jan 2026

Use Of Enterococcus Faecalis And Cetylpyridinium Chloride In Altering Canine Mouth Microbiome, Quigley D. Espinola, Scarlet Renner, Curtis Cline, Sofia Lopez-Orenday, Alex Yasumatsu

Humboldt Journal of Microbiology

Like most mammals, canines have copious amounts of bacteria in their oral cavity. While some of these bacteria are beneficial and even necessary to their health, overgrowth of harmful bacterial strains can lead to plaque buildup and gum disease. To combat plaque and bacteria, several products are marketed towards canines. In this study, we aim to explore how the microbiome of the canine mouth is affected by a potential probiotic, Enterococcus faecalis, and an antimicrobial water additive found in dog mouthwash products, Cetylpyridinium chloride monohydrate (CCM). We hypothesized that both would be successful in their ability to decrease harmful bacteria. …


Western Massasauga (Sistrurus Tergeminus): A Species Conservation Assessment For The Nebraska Natural Legacy Project, Colleen Rothe-Groleau, Melissa J. Panella Jan 2026

Western Massasauga (Sistrurus Tergeminus): A Species Conservation Assessment For The Nebraska Natural Legacy Project, Colleen Rothe-Groleau, Melissa J. Panella

Nebraska Game and Parks Commission: Publications

The Nebraska Natural Legacy Project recognizes the western massasauga (Sistrurus tergeminus) as a Tier I at-risk species. Provided are some general management recommendations regarding western massasaugas. Conservation practitioners will need to use professional judgment to make specific management decisions based on objectives, location, and a multitude of variables. This resource was designed to share available knowledge of this at-risk species that will aid in the decision-making process or in identifying research needs to benefit the species.

Criteria for selection as Tier I: State listed, G3

Estimated Population in NE: 1,000–2,500

Estimate based on: Field surveys

Trends since 2005 …


Typology And Spatiotemporal Patterns Of Illegal Fishing Activities In The Philippines: Implications For Fisheries Management, Marlowe O. Acevedo, Tzu-Yun Ching, Chih-Shin Chen Jan 2026

Typology And Spatiotemporal Patterns Of Illegal Fishing Activities In The Philippines: Implications For Fisheries Management, Marlowe O. Acevedo, Tzu-Yun Ching, Chih-Shin Chen

Journal of Marine Science and Technology–Taiwan

Illegal, unreported, and unregulated (IUU) fishing activity is a global threat and continues to undermine the effectiveness of fisheries regulations and management measures. However, the extent of illegal fishing in Philippine waters remains unclear. This study aims to identify the types of illegal fishing in Philippine waters and analyzed their temporal and spatial patterns. Data were obtained from the records of the Philippine Coast Guards (PCG) and Maritime Law Enforcement Agencies from 2015 to 2020. A total of 602 apprehensions were recorded, resulting in 813 violations, of which 630 cases were fishery violations. Most of the watercrafts involved in the …


Balancing Inquiry Based Learning And Direct Instruction, Sharon Liu , '26 Jan 2026

Balancing Inquiry Based Learning And Direct Instruction, Sharon Liu , '26

Senior Theses, Projects, and Awards

No abstract provided.


Managing The Legacy Of Historical Land Use In Central Appalachia: Soil Health, Carbon Storage, And Restoration Across Disturbed Ecosystems, Kyra R. Dukich Jan 2026

Managing The Legacy Of Historical Land Use In Central Appalachia: Soil Health, Carbon Storage, And Restoration Across Disturbed Ecosystems, Kyra R. Dukich

Graduate Theses, Dissertations, and Problem Reports (ETD)

Historical mining, intensive timber harvesting, agriculture, and atmospheric acid deposition have left lasting impacts on soil health throughout the Central Appalachian region, reducing soil productivity, carbon storage, and ecosystem resilience. This thesis evaluated restoration strategies across two long-term research systems in West Virginia to determine how land-use history and soil amendments influence soil health, carbon dynamics, and ecosystem recovery. The first study examined reclaimed mine lands and marginal agricultural soils planted with switchgrass (Panicum virgatum) or willow (Salix spp.) and treated with biochar or inorganic fertilizer. Soil greenhouse gas production, aggregate stability, total soil C:N, pH, and soil organic matter …


Examining Drivers Of Brook Trout (Salvelinus Fontinalis) Fecundity And Recruitment In Central Appalachian Headwater Streams, Emilee Esther Briggs Jan 2026

Examining Drivers Of Brook Trout (Salvelinus Fontinalis) Fecundity And Recruitment In Central Appalachian Headwater Streams, Emilee Esther Briggs

Graduate Theses, Dissertations, and Problem Reports (ETD)

The persistence of fish populations depends on the repeated production and survival of new year classes, also referred to as recruitment. Recruitment is broadly defined as the number of individuals in a fish population or stock that survive to a specific stage. However, the broader recruitment process reflects the cumulative outcome of many earlier life stages, including egg survival, fry emergence, and survival through the recruitment period. As a result, recruitment can vary substantially among years and populations, producing strong or weak year classes that influence population abundance and persistence. Understanding why recruitment varies is therefore central to fisheries ecology …


Ornithine Metabolism In Retinal Pigment Epithelium And Retina And Implications In Gyrate Atrophy, Artjola Puja Jan 2026

Ornithine Metabolism In Retinal Pigment Epithelium And Retina And Implications In Gyrate Atrophy, Artjola Puja

Graduate Theses, Dissertations, and Problem Reports (ETD)

Ornithine aminotransferase (OAT) is a mitochondrial enzyme that regulates ornithine metabolism by converting ornithine to pyrroline-5-carboxylate, a precursor for proline and glutamate synthesis. Deficiency of OAT causes systemic ornithine accumulation and leads to gyrate atrophy (GA) of the choroid and retina, a hereditary disorder characterized by progressive chorioretinal degeneration and irreversible vision loss. Chorioretinal atrophy typically starts at the mid-peripheral retina and progresses toward the macula. Although elevated ornithine is considered toxic to the eye, how ornithine is metabolized in ocular tissues and why OAT deficiency causes selective, region-specific vulnerability remain unclear. We combined ex vivo and in vivo stable …


Surrogate-Based Approaches For Evaluating Post-Harvest Food Safety Interventions In Fresh Produce, Md Shafiul Islam Rion Jan 2026

Surrogate-Based Approaches For Evaluating Post-Harvest Food Safety Interventions In Fresh Produce, Md Shafiul Islam Rion

Graduate Theses, Dissertations, and Problem Reports (ETD)

Pathogenic bacteria are still a threat to human beings worldwide as their presence is often unknown even if they are already present in fresh produces. This in turn resulted in several outbreaks and recalls across the United States. This dissertation investigated the survival of pathogenic bacteria and their potential non-pathogenic surrogates after antimicrobial interventions in different modes of applications on the surface of cantaloupes, butternut squash, and fresh cilantro. In the first study, peroxyacetic acid (PAA) was applied in three separate doses on nalidixic acid resistant Salmonella Typhimurium, Listeria monocytogenes, Enterococcus faecium, and Listeria innocua inoculated cantaloupe surfaces …


Exploring The Application Of Wastewater Monitoring To Determine The Prevalence And Diversity Of Influenza On The Campus Of West Virginia University, Lakyn Renee Sanders Jan 2026

Exploring The Application Of Wastewater Monitoring To Determine The Prevalence And Diversity Of Influenza On The Campus Of West Virginia University, Lakyn Renee Sanders

Graduate Theses, Dissertations, and Problem Reports (ETD)

Influenza viruses (IV) affect populations globally, with the World Health Organization (WHO) estimating that IV are responsible for an estimated 3-5 million infections and 290,000 – 650,000 deaths annually1–3. More specifically, the 2019-2020 IV season is associated with an estimated 38 million illnesses and 22,000 deaths in the United States alone4. IV are rapidly spread between individuals through direct contact with infected individuals, contaminated surfaces, or aerosolized virus particles2. Traditional IV infection monitoring relies on clinical screening of patients presenting influenza-like symptoms, commonly through the use of multi-target panel tests such as the BioFire …


Preliminary Analysis Of Soil Volatile Organic Compounds As Soil Health Indicators, Thorne Taul Jan 2026

Preliminary Analysis Of Soil Volatile Organic Compounds As Soil Health Indicators, Thorne Taul

Graduate Theses, Dissertations, and Problem Reports (ETD)

Over the past decade, soil health (SH) has gained popularity due to the novelty of sustainable soil use related to human wellbeing. Soil health describes the overall quality of soil and its capacity to function over time. As interest in SH grows, researchers continue to explore new soil health indicators that can improve knowledge on how soil health is assessed and managed. Some indicators directly reflect soil health status, and some indirectly relate to processes and functions occurring within the soil. Volatile organic compounds (VOCs) are naturally occurring compounds that play a role in multiple soil processes. They are associated …


The Role Of Temperature And Carbon Source In Nutrient Acquisition For Peptidoglycan Synthesis In A Gfp-Expressing Borreliella Burgdorferi, Barrett-Anne Conner Briggs Jan 2026

The Role Of Temperature And Carbon Source In Nutrient Acquisition For Peptidoglycan Synthesis In A Gfp-Expressing Borreliella Burgdorferi, Barrett-Anne Conner Briggs

Graduate Theses, Dissertations, and Problem Reports (ETD)

Lyme disease is the most common vector-borne disease in the United States with an estimated yearly incidence rate of more than 300,000 cases. Borreliella burgdorferi, the etiological agent of Lyme disease, is transmitted by the bite of an infected Ixodes scapularis tick and can cause debilitating pathologies affecting numerous body systems. Symptoms include fever, fatigue, joint pain, and a characteristic bull’s eye rash (erythema migrans) at the site of the tick bite. The timely and appropriate use of antibiotics effectively treats early Lyme disease; however, uncomfortable side effects reduce treatment compliance. If left untreated, long-term complications can arise including facial …


Reducing Inorganic Phosphorus In Poultry Diets: Nutritional Constraints And Strategies For Successful Implementation, Elizabeth Ann Lynch Jan 2026

Reducing Inorganic Phosphorus In Poultry Diets: Nutritional Constraints And Strategies For Successful Implementation, Elizabeth Ann Lynch

Graduate Theses, Dissertations, and Problem Reports (ETD)

Applied poultry nutrition and feed manufacture science can be described as a “three-legged stool” supported by pellet quality, feed hygienics, and nutrient availability, where imbalance in any one component can compromise overall bird performance. The research presented herein primarily addresses feed hygienics and nutrient availability, with pellet quality serving as an underlying theme, to better understand how processing conditions and dietary formulation influence performance and nutrient utilization.

In Chapter 2, the objective of this study was to evaluate the effects of hygienizer retention time on bacterial reduction during feed manufacture using Enterococcus faecium as a Salmonella surrogate. Pellet mill motor …


Using Side Looking Hydroacoustics And Community Size Spectra To Assess Invasive Carp’S Impact On Fish Assemblage Integrity, Daniel Jacob Bryan Jan 2026

Using Side Looking Hydroacoustics And Community Size Spectra To Assess Invasive Carp’S Impact On Fish Assemblage Integrity, Daniel Jacob Bryan

Graduate Theses, Dissertations, and Problem Reports (ETD)

Often accounting for over half of total fish biomass, invasive silver carp have dramatically reshaped the ecosystem of the Mississippi River and its tributaries. These high silver carp densities have been shown to affect native fish body condition, abundance, and community structure, highlighting the need for efficient methods to quantify silver carp’s effect on the native fish assemblage. Community size spectra (CSS) is a metric that quantifies fish assemblage body size structure based on the decrease in fish abundance with increasing size. To estimate silver carp’s effects on CSS in the Ohio River, side looking hydroacoustic monitoring was used alongside …


Synaptic Connectivity Of Rod Bipolar Cells In The Mouse Retina: A Connectomic Analysis Using Webknossos, Harold F. Eshun Jan 2026

Synaptic Connectivity Of Rod Bipolar Cells In The Mouse Retina: A Connectomic Analysis Using Webknossos, Harold F. Eshun

Williams Honors College, Honors Research Projects

Rod bipolar cells (RBCs) are key interneurons in the mouse retina that transmit signals from rod photoreceptors to downstream amacrine and ganglion cells under scotopic (low-light) conditions. Although their general morphology and function are well established, the fine-scale organization of their synaptic inputs and outputs remains incompletely characterized. This project aims to map the pre- and postsynaptic partners of a fully reconstructed rod bipolar cell using the Yu volume, a serial block-face electron microscopy dataset from the ventral retina of an adult wild-type mouse. Using the webKnossos platform, I identify synaptic ribbons in the axon terminals of the rod bipolar …


An Investigation Into The Potential Role Of Thioester Bonds In Prebiotic Atp Synthesis, Adam J. Ruf Jan 2026

An Investigation Into The Potential Role Of Thioester Bonds In Prebiotic Atp Synthesis, Adam J. Ruf

Williams Honors College, Honors Research Projects

In this project I will attempt to show a potential prebiotic pathway for the synthesis of ATP. This pathway involves the use of thioester bond containing molecules, as derivatives of these bonds have been shown to exhibit enzyme-like catalytic properties. Nuclear magnetic resonance spectroscopy will be utilized to characterize each step of the pathway to ensure it is successful.


Spiders In The World Of Pesticides: A Review, Jackson L. Mendillo Jan 2026

Spiders In The World Of Pesticides: A Review, Jackson L. Mendillo

Williams Honors College, Honors Research Projects

Pesticides and other agrochemicals have varying effects on spiders depending on their mechanism of action and dosage, ranging from behavioral changes and ataxia, to reproductive changes and physiological stress, to lethal non-target effects. Additionally, peptide Hv1a has promising effects as a more narrow-spectrum pesticide.


Pipeline Corrosion And Relevant Microbial Influence, Renee E. Bamberger Jan 2026

Pipeline Corrosion And Relevant Microbial Influence, Renee E. Bamberger

Williams Honors College, Honors Research Projects

This study investigated the role of microbial activity and oxygen availability in the corrosion of carbon steel pipelines with a focus on microbially influenced corrosion (MIC). Sediment collected from Old Woman Creek, Ohio, was used to simulate natural soil conditions, and carbon steel coupons were incubated under four treatments: nonsterile oxic, nonsterile anoxic, autoclaved oxic, and autoclaved anoxic over 85 days. Corrosion was assessed through mass loss measurements and the analysis of pH, sulfate, chloride, and dissolved iron concentrations. The greatest mass loss was observed in autoclaved oxic conditions, contrary to the initial hypothesis that microbial activity would greatly enhance …


Reconnecting The Body With Nature: Inspired By Advances In Biomimicry, Elyse M. Orosa Jan 2026

Reconnecting The Body With Nature: Inspired By Advances In Biomimicry, Elyse M. Orosa

Williams Honors College, Honors Research Projects

Reconnecting the Body with Nature: Inspired by Advances in Biomimicry will visually address the symbiotic relationship between nature and humans. The drawing series is inspired by the growing design field of biomimicry and its technological and architectural innovations influenced by nature’s systems and physical adaptations. Just as nature is limited by human misuse, humans are physically and neurologically limited by the state of the environment, and with this, form and function of both nature and humans will be equally represented and explored throughout the body of work presented. Biomimicry can help solve environmental issues such as rising CO2 emissions and …


C. Difficile Detection Method For First Responder Glove Application, Alli N. Senedak Jan 2026

C. Difficile Detection Method For First Responder Glove Application, Alli N. Senedak

Williams Honors College, Honors Research Projects

Clostridioides Difficile (C. diff) is a Anaerobic Gram-positive bacillus that is capable of spore formation, making it difficult to control its spread and duration in clinical environments. This phenomenon can provide danger to first responders, healthcare workers, and patients. The goal of this project is to create a biosensor capable of detecting C. diff in a clinical setting that can be applied to a glove apparatus. The project will involve the use of C. diff aptamers activated on the surface of an electrode. Once surface activation has been verified via surface analysis, the electrodes will be exposed to C. diff …


Repurposing Cyclin-Dependent Kinase Inhibitors For The Discovery Of Novel Antiplasmodial Compounds, Ritam Bhowmik Jan 2026

Repurposing Cyclin-Dependent Kinase Inhibitors For The Discovery Of Novel Antiplasmodial Compounds, Ritam Bhowmik

Honors Undergraduate Theses

Malaria remains a major global health burden with over 282 million cases annually and rising resistance to artemisinin-based combination therapies. Plasmodium falciparum, the most lethal malaria parasite species in humans, relies on tightly regulated cell cycle progression during replication within red blood cells. Cyclin-dependent kinases (CDKs) are central regulators of eukaryotic cell division and transcription, and several CDK-like enzymes in P. falciparum, including Pfmrk and PfPK6, are essential for parasite growth and structurally distinct from human kinases. This study evaluated whether commercially available human CDK inhibitors (CDKIs) targeting cancer pathways could be repurposed as novel antimalarial compounds. A library of …


Manuka Honey Modulates Oxidative Stress In Neuro2-A Cells Through Mitochondrial Regulation, Rachel Abramovici Jan 2026

Manuka Honey Modulates Oxidative Stress In Neuro2-A Cells Through Mitochondrial Regulation, Rachel Abramovici

Honors Undergraduate Theses

Manuka honey is known for its vital usage in wound healing, being an agonist towards fighting infections, and is an acting antioxidant [32]. Its main constituents are flavonoids and phenolic compounds, with methyl syringate (MSYR) being a major active ingredient. The specific compounds responsible for these antioxidant effects, particularly in the CNS, remain unclear. It is hypothesized that pre-treatment of mouse neuroblastoma cells with MSYR followed by hydrogen peroxide exposure will activate the AMPK/SIRT1/PGC-1a pathway, due to MSYR’s phenolic structure, and thus reduce oxidative stress and improve mitochondrial biogenesis. Hydrogen peroxide is a standard reactive oxygen species (ROS) treatment to …


Impact Of Lifestyle Factors On Allergic Rhinitis Symptoms And Quality Of Life Among College Students, Lina Saint-Hilaire Jan 2026

Impact Of Lifestyle Factors On Allergic Rhinitis Symptoms And Quality Of Life Among College Students, Lina Saint-Hilaire

Honors Undergraduate Theses

This study aims to examine the influence of certain lifestyle factors on the presentation of allergic rhinitis symptoms and the quality of life of college students. Factors of interest include residential setting, household cleaning habits, age of symptom onset, and exposure to household pets. Additional analysis includes assessment of the impact of allergic rhinitis symptoms on sleep. Using a cross-sectional survey design, student responses were self-reported through a paper survey distributed during tabling days at the University of Central Florida (UCF) main campus. Eligible participants had to be 18 years or older and current UCF graduate and undergraduate students. Survey …


Multicomponent Deoxyribozyme Probes For Targeted Detection Of Cancer Associated Gene Insertions, Samuel R. Veleke Jan 2026

Multicomponent Deoxyribozyme Probes For Targeted Detection Of Cancer Associated Gene Insertions, Samuel R. Veleke

Honors Undergraduate Theses

Insertions and deletions (indels) in DNA sequences of genes are linked with cancers such as glioblastoma (GB). Thus, indels may be used as potential cancer biomarkers. In the NANOG gene, its pseudogene NANOGP8 has a 22 base pair insertion sequence for GB patients. In this work, the NANOG gene and the insertion sequence were detected in one sample using a dual-fluorescent assay containing two multicomponent split deoxyribozyme (Dz) probe complexes. One complex used TXR fluorescence to detect the gene regardless of the insertion’s presence. The other complex used fluorescein (FAM) fluorophore to detect the insertion. The probes were able to …


Investigating The Interaction Of Gram-Positive Lactobacillus Species With Mucin In The Context Of Barrett's Esophagus, Ritisha Suresh Jan 2026

Investigating The Interaction Of Gram-Positive Lactobacillus Species With Mucin In The Context Of Barrett's Esophagus, Ritisha Suresh

Honors Undergraduate Theses

Gastroesophageal Reflux Disease (GERD) can progress to the precancerous Barrett’s Esophagus (BE) condition, in which the normal esophageal squamous epithelium is replaced with a columnar epithelium containing goblet cells. Mucins, sticky substances, are secreted in response to bile acid exposure during reflux episodes to protect the esophageal epithelium. Goblet cells secrete these mucins, which can also scaffold microbial colonization. Probiotic Lactobacillus bacteria can use glycosidase enzymes to process mucin and metabolize them into their component sugars (glycans). This project aims to identify the role of the Lactobacillus-mucin interaction in BE, as glycan availability could confer an advantage to Lactobacillus …


Feeding Mode Is Associated With Infant Night Sleep Trajectories During The First Postnatal Year, Magdalena Olson, Li Liu, Elizabeth Reifsnider, Dean V. Coonrod, Sarada S. Panchanathan, Megan E. Petrov, Corrie M. Whisner Jan 2026

Feeding Mode Is Associated With Infant Night Sleep Trajectories During The First Postnatal Year, Magdalena Olson, Li Liu, Elizabeth Reifsnider, Dean V. Coonrod, Sarada S. Panchanathan, Megan E. Petrov, Corrie M. Whisner

Ellmer School of Nursing Faculty Publications

Background: Short sleep and formula feeding during infancy are associated with increased risk of childhood obesity. Feeding practices and sleep arrangements vary during infancy and may also be dynamic, yet their impact on infant night sleep duration remains unclear. Understanding these relationships is crucial for formulating recommendations to support breastfeeding and address sleep concerns. Objective: We examined the association between feeding mode and parent-reported infant night sleep duration during the first postnatal year, while additionally evaluating night-weaning and bedsharing as contextual sleep-related practices. Methods: Infants in the Phoenix Metropolitan Area (n = 193) were followed up at 3, 8, 13, …