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Articles 56581 - 56610 of 255948

Full-Text Articles in Life Sciences

Arundinella Stenostachya (Arundinella, Poaceae), A Reevaluated New Species From Se Asia, Liqiong Jiang, Zhenwen Liu, Ende Liu, Atchara Teerawatananon, Yuehua Wang, Hua Peng Jan 2022

Arundinella Stenostachya (Arundinella, Poaceae), A Reevaluated New Species From Se Asia, Liqiong Jiang, Zhenwen Liu, Ende Liu, Atchara Teerawatananon, Yuehua Wang, Hua Peng

Turkish Journal of Botany

Arundinella stenostachya, a new species, is described and illustrated. It is morphologically similar to A. decempedalis and A. bengalensis, but differs from the former species by the length of panicle branches, type of trichome on nodes and pedicels length, and from the latter in height and diameter of culms, the length and width of leaf blades, pedicels length, and the length of panicles and branches. The new species has been mistakenly identified as A. decempedalis and A. bengalensis. Molecular analyses based on ITS sequences also support A. stenostachya as a distinct species.

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Dna Barcoding Analysis And Phylogenetic Relationships Of Indian Wild Coffee Species, Manoj Mishra, Pavankumar Jingade, Arun Kumar C Huded Jan 2022

Dna Barcoding Analysis And Phylogenetic Relationships Of Indian Wild Coffee Species, Manoj Mishra, Pavankumar Jingade, Arun Kumar C Huded

Turkish Journal of Botany

Wild coffee species are the reservoirs of genetic diversity and could play a critical role in the genetic improvement of coffee. However, the conservation and genetic assessment of wild coffee species has been largely neglected. In the present study, DNA barcoding approaches were employed to assess the phylogenetic relationships between five indigenous wild coffee species from India and compared with two cultivated, and four wild coffee species of African origin. The efficacy of three barcoding loci namely matK,rbcL, and trnL-trnF was investigated using PCR amplification and sequence characterization. The intergenic spacer trnL-trnF is the highly polymorphic loci followed by matK …

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Chromosome Numbers And Genome Size Data On Species Of The Genus Petrorhagia(Caryophyllaceae) From Turkey, Kamuran Aktaş, Jaume Pellicer, Teresa Garnatje Jan 2022

Chromosome Numbers And Genome Size Data On Species Of The Genus Petrorhagia(Caryophyllaceae) From Turkey, Kamuran Aktaş, Jaume Pellicer, Teresa Garnatje

Turkish Journal of Botany

Genome size, i.e. the total amount of DNA in an unreplicated somatic nucleus is considered an important character in the biology of organisms, and it is especially relevant for land plants given the extraordinary diversity reported. Despite the continuous growth of data and the efforts aimed at increasing our understanding of plant genome size diversity, more data are needed to have an evenly representation across lineages. With this premise in mind, in this work, we investigated genome size, complemented with chromosome data in eight species of the genus Petrorhagia (Caryophyllaceae) from Turkey. Chromosome counts made indicate that the species studied …

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Chemical Fingerprints And Bioactivities Of 12 Anatolian Achillea Species By Lc-Ms/Ms With Chemometric Approach: Novel Phytonutrients, Natural Food Preservatives And Chlorogenic Acid Sources, Mustafa Abdullah Yilmaz, Abdulselam Ertaş, İsmai̇l Yener, Fatma Pinar Türkmenoğlu, Özge Tokul Ölmez, Mehmet Öztürk, Muhammed Altun, Oğuz Çakir, Abbas Tarhan, Mehmet Boğa, İbrahi̇m Demi̇rtaş, Mehmet Hakki Alma, Hamdi̇ Temel Jan 2022

Chemical Fingerprints And Bioactivities Of 12 Anatolian Achillea Species By Lc-Ms/Ms With Chemometric Approach: Novel Phytonutrients, Natural Food Preservatives And Chlorogenic Acid Sources, Mustafa Abdullah Yilmaz, Abdulselam Ertaş, İsmai̇l Yener, Fatma Pinar Türkmenoğlu, Özge Tokul Ölmez, Mehmet Öztürk, Muhammed Altun, Oğuz Çakir, Abbas Tarhan, Mehmet Boğa, İbrahi̇m Demi̇rtaş, Mehmet Hakki Alma, Hamdi̇ Temel

Turkish Journal of Botany

The objective of this study was to evaluate the biological activities and chemical fingerprint profiles of the extracts obtained from twelve Achillea L. species (A. lycaonica, A. biebersteinii (syn: A. arabica), A. kotschyi subsp. kotschyi, A. schischkinii, A. millefolium subsp. millefolium, A. sintenisii, A. setacea, A. teretifolia, A. wilhelmsii subsp. wilhelmsii (syn: A. santolinoides subsp. wilhelmsii), A. nobilis, A. goniocephala, A. spinulifolia). The antioxidant, enzyme inhibitory and cytotoxic effects were evaluated to investigate their bioactivity profiles. Furthermore, the total flavonoid and phenolic contents were determined and LC-MS/MS analysis was performed to reveal the phytochemical profile of the investigated extracts. A. …

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Taxonomy And Phylogeny Of A New Species Of Pseudocercospora On Solanum Nigrum From India, Archana Singh, Sanjay Yadav, Raghvendra Singh, Nawal Dubey Jan 2022

Taxonomy And Phylogeny Of A New Species Of Pseudocercospora On Solanum Nigrum From India, Archana Singh, Sanjay Yadav, Raghvendra Singh, Nawal Dubey

Turkish Journal of Botany

A new species Pseudocercospora solanicola is discovered causing severe leaf spot disease on Solanum nigrum from Sonebhadra. Species is described and illustrated based on morphology, molecular sequence analysis and phylogeny of the large subunit (LSU) and internal transcribed spacer region of the nuclear ribosomal RNA (rRNA) gene. Morphologically, new species has similarity with allied species in Pseudocercospora but differs in having black circular, velvety leaf spot and size of stromata, conidia and conidiophores. A key to Pseudocercospora species on Solanum has been provided.

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Lamium Cappadocicum, A New Species From Central Anatolia, Turkey: Evidence From Molecular And Morphological Studies, Ferhat Celep, Fergan Karaer, Bryan T. Drew Jan 2022

Lamium Cappadocicum, A New Species From Central Anatolia, Turkey: Evidence From Molecular And Morphological Studies, Ferhat Celep, Fergan Karaer, Bryan T. Drew

Turkish Journal of Botany

Lamium is a taxonomically convoluted genus of about 34 species. Within Lamium, the L. garganicum species complex is particularly challenging. Here, based on morphological and molecular studies, Lamium cappadocicum Celep & Karaer sp. nova (Lamiaceae) is separated from L. garganicum and L. bilgilii and described as a new species, and L. garganicum subsp. rectum (= L. garganicum subsp. pulchrum) is resurrected. The new species is only known from the Hasan Mountain (Aksaray) in Central Anatolia, Turkey. Lamium cappadocicum is closely related to L. garganicum subsp. rectum but differs from it by its mat-forming caespitose habit, reniform (rarely ovate …

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Pulmonary Response To Exercise, Woodsmoke, And Acute Sleep Deprivation, Aidan Da Mccloy, Joseph A. Sol, John C. Quindry Jan 2022

Pulmonary Response To Exercise, Woodsmoke, And Acute Sleep Deprivation, Aidan Da Mccloy, Joseph A. Sol, John C. Quindry

Undergraduate Theses, Professional Papers, and Capstone Artifacts

Our laboratory studied the combined effects of smoke exposure, exercise, and sleep deprivation to better understand the causes of the long-term deleterious health effects of woodsmoke in at risk populations, such as wildland firefighters. The purpose of this paper is to report on the results of our pulmonary function tests (PFT). Ten recreationally active male participants (age = 24±4 yrs.; height = 185.2±3.9 cm; weight = 85.7±9.4 kg; VO2max = 46.8.7±.7 ml∙min¯¹∙kg¯¹; body fat = 12.6±6.7 %) performed two separate 45-minute stationary bicycle workouts (70% VO2max) while exposed to woodsmoke particulate matter <2.5um (PM2.5) at a concentration of 250μg/m3. One trial was performed on 8 hours of sleep and the other on 4 hours of sleep. Duplicate pulmonary data for key dependent measures of PFT (FVC, FEV1%, MVV) taken before and after each workout showed no statistically significant differences between trials or across trials when examined by a two-way ANOVA analysis (FVC time p = 0.949, trial p=0.919, time-trial p=0.837; FEV1 time p=0.684, trial p=0.769, time-trial p=0.857; FEV1% time p=0.540, trial p=0.712, time-trial p=0.986; MVV time p=0.917, trial p=0.633, time-trial p=0.923). These results are consistent with the literature from participants with normal sleep patterns.1 No alterations in acute measures of pulmonary function were observed in apparently healthy individuals exposed to PM2.5 250μg/m3 of woodsmoke during exercise, nor does acute sleep deprivation alter these results.

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Combining Gwas And Population Genomic Analyses To Characterize Coevolution In A Legume-Rhizobia Symbiosis, Brendan Epstein, Liana T. Burghardt, Katy D. Heath, Michael A. Grillo, Adam Kostanecki, Toumas Hämälä, Nevin D. Young, Peter Tiffin Jan 2022

Combining Gwas And Population Genomic Analyses To Characterize Coevolution In A Legume-Rhizobia Symbiosis, Brendan Epstein, Liana T. Burghardt, Katy D. Heath, Michael A. Grillo, Adam Kostanecki, Toumas Hämälä, Nevin D. Young, Peter Tiffin

Biology: Faculty Publications and Other Works

The mutualism between legumes and rhizobia is clearly the product of past coevolution. However, the nature of ongoing evolution between these partners is less clear. To characterize the nature of recent coevolution between legumes and rhizobia, we used population genomic analysis to characterize selection on functionally annotated symbiosis genes as well as on symbiosis gene candidates identified through a two-species association analysis. For the association analysis, we inoculated each of 202 accessions of the legume host Medicago truncatula with a community of 88 Sinorhizobia (Ensifer) meliloti strains. Multistrain inoculation, which better reflects the ecological reality of rhizobial selection in nature …

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Not Coming Home: The Flaws In Skilled Nursing Facilities And Their Contribution To Cyclical Hospitalizations Of Post-Acute Patients, Kate Eisenbraun Jan 2022

Not Coming Home: The Flaws In Skilled Nursing Facilities And Their Contribution To Cyclical Hospitalizations Of Post-Acute Patients, Kate Eisenbraun

Pitzer Senior Theses

This literature review will discuss the experience of patients within the US healthcare system, focusing on skilled nursing facilities (SNFs) and their contribution to cyclical hospitalizations. SNFs differ from nursing homes and other long-term care facilities by providing short-term, post-operational rehabilitation at a cost lower than what is offered at hospitals. Despite their critical role, SNFs often face fundamental issues, such as understaffing, underfunding, and staff burn-out, which result in lower quality patient care. This thesis argues that the issues faced by SNFs are a result of inconsistencies with state and federal staffing regulations, as well as inadequate insurance reimbursements. …

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Validation Of The Use Of Clathromorphum Compactum Growth And Skeletal Δ18o As A Proxy For Seawater Conditions, Teagan Mcmahon Jan 2022

Validation Of The Use Of Clathromorphum Compactum Growth And Skeletal Δ18o As A Proxy For Seawater Conditions, Teagan Mcmahon

Pitzer Senior Theses

Crustose coralline algae (CCA) are important organisms that create benthic habitat in the photic zone of oceans worldwide. CCAs mechanisms of photosynthesis and calcification may, in some cases, make them vulnerable to climate change and ocean acidification. Therefore, CCA are important not only for their ecological role within ecosystems but also for their ability to indicate the effects that ocean acidification and climate change may have on other marine calcifying organisms. Some species of CCA are known to be useful recorders of paleo oceanic conditions. These climate archives and reconstructions of past environmental conditions are important for understanding past changes …

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Velocity Field Measurements Of The California Sea Lion Propulsive Stroke Using Bubble Piv, Gino Perrotta, Frank E. Fish, Danielle S. Adams, Ariel M. Leahy, Abigal M. Downs, Megan C. Leftwich Jan 2022

Velocity Field Measurements Of The California Sea Lion Propulsive Stroke Using Bubble Piv, Gino Perrotta, Frank E. Fish, Danielle S. Adams, Ariel M. Leahy, Abigal M. Downs, Megan C. Leftwich

Biology Faculty Publications

California sea lions are among the most agile of swimming mammals. Most marine mammals swim with their hind appendages-flippers or flukes, depending on the species-whereas sea lions use their foreflippers for propulsion and maneuvering. The sea lion's propulsive stroke generates thrust by forming a jet between the flippers and the body and by dragging a starting vortex along the suction side of the flipper. Prior experiments using robotic flippers have shown these mechanisms to be possible, but no flow measurements around live sea lions previously existed with which to compare. In this study, the flow structures around swimming sea lions …

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A Look Into Alzheimer’S Disease—Interventions At The Molecular Level, Priscila Feliciano Nieves Jan 2022

A Look Into Alzheimer’S Disease—Interventions At The Molecular Level, Priscila Feliciano Nieves

Honors Undergraduate Theses

There are puzzle pieces to the cure for Alzheimer’s Disease (AD), and such can emerge by inspecting the biomolecular interactions and their effects on neuronal cells. The upcoming presented literature review will cover the molecular changes caused by AD pathological progression, explore the relationship between non-AD molecules and AD molecules in the body, and analyze potential contributing factors in AD. In addition, the information to be provided will highlight medicinal alternatives respective to a particular stage in AD.

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Methods For Characterization Of Cl-001 Derived Exosomes As A Stimulating Agent For Nk Cells For Immunotherapy, Ilana Gomez Diaz Jan 2022

Methods For Characterization Of Cl-001 Derived Exosomes As A Stimulating Agent For Nk Cells For Immunotherapy, Ilana Gomez Diaz

Honors Undergraduate Theses

The immune system is a complex set of cells in the body that work to prevent disease or infection by recognizing and eliminating foreign material or unhealthy cells. One essential type of immune cell that is part of the innate immune response are Natural Killer (NK) cells. These cytotoxic effector lymphocytes can detect certain unhealthy cells, such as cancer cells, that normal B and T cells would miss. For example, many tumor cells have evolved to bypass immune system surveillance by not expressing major histocompatibility complex class I molecules (MHC class I), on their surface, reducing recognition by cytotoxic T …

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The Effect Of Young Blood Anti-Aging Treatment On Protein Markers Of Age And Huntington Disease, Sujena H. Koilpillai Jan 2022

The Effect Of Young Blood Anti-Aging Treatment On Protein Markers Of Age And Huntington Disease, Sujena H. Koilpillai

Honors Undergraduate Theses

Huntington disease (HD) is a neurodegenerative disorder caused by expansion of a polyglutamine tract within the huntingtin (HTT) protein, forming mutant HTT (mtHTT). HD patients suffer from psychiatric, behavioral, cognitive, and motor abnormalities, with death typically occurring 15-20 years after symptom onset. Currently, there are no treatments able to slow disease progression or delay onset. HD is a disease of aging. Despite the mtHTT protein being produced throughout life, symptoms do not typically appear until adulthood. Furthermore, many cellular effects of normal aging are also seen in HD, including altered intercellular communication and loss of proteostasis. Recently, our lab found …

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The Use Of Exogenous Acrp30 As A Promising Amelioratory Compound Regarding Insulin Resistance And Type Ii Diabetes Mellitus, Stephen L. Romero Jan 2022

The Use Of Exogenous Acrp30 As A Promising Amelioratory Compound Regarding Insulin Resistance And Type Ii Diabetes Mellitus, Stephen L. Romero

Honors Undergraduate Theses

As numerous bodies of research have characterized the adipocytokine adiponectin (ACRP30) as an anti-diabetic compound, this work serves as an analysis to partly elucidate the potential usage of supplementary adiponectin as a therapeutic compound in the treatment of type II diabetes mellitus. In this work, a meta-analysis was conducted to centralize large amounts of data on adiponectin’s insulin sensitizing characteristics in conjunction with like-minded studies utilizing metformin treatment as the diabetic standard of care. Upon comparison of fasting glucose, fasting insulin, and glucose tolerance test area under the curve reduction percentages, it is quite clear that ACRP30 has significant insulin …

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Investigation Of Dna Hybridization In Localized Systems In Close Proximity, Ashley M. Sewsankar Jan 2022

Investigation Of Dna Hybridization In Localized Systems In Close Proximity, Ashley M. Sewsankar

Honors Undergraduate Theses

Hybridization of two or more DNA or RNA strands is well documented for the process taking place with all strands free in solution or when one strand is immobilized on a substrate. This study contributes to the investigation of the hybridization process when two single DNA strands (ssDNA) are in close proximity. We took advantage of an X sensor in which hybridization of four DNA strands enables the formation of a DNA four-way junction (crossover or X) structure. We immobilized multiple layers of crossover structures to study its hybridization being triggered by short ssDNA coming from solution and further investigate …

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The Role Of The Prefrontal Cortex And Stress In Huntington Disease-Mediated Aggression, Kadambari Vyas Jan 2022

The Role Of The Prefrontal Cortex And Stress In Huntington Disease-Mediated Aggression, Kadambari Vyas

Honors Undergraduate Theses

Huntington Disease (HD) is a fatal neurodegenerative disorder that is characterized by motor, cognitive, and psychiatric symptoms. Although HD onset is determined by motor symptoms, psychiatric symptoms, like depression and aggression, can develop earlier, have a larger impact on quality of life, and are understudied due to stigma. Our lab has observed hyper aggression in our humanized HD mouse model (Hu97/18) compared to our knock-in HD mouse model (Q175FDN). We characterized these differences and found that the Hu97/18 mice overreact in neutral situations, behaving as if they are in threatening situations. We are now using this novel model of HD-related …

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The Relationship Between Inflammatory Diet Score And Cancer Outcomes: Systematic Review And Meta-Analysis, Eric Han Jan 2022

The Relationship Between Inflammatory Diet Score And Cancer Outcomes: Systematic Review And Meta-Analysis, Eric Han

Honors Undergraduate Theses

Cancer remains one of the most prevalent diseases in the United States and a leading cause of death. Large prospective studies have found significant correlations between dietary intake and cancer. Chronic inflammation promotes pro-cancer inflammatory environments promoting the formation and growth of tumors while preventing effective anti-tumor responses. Nutrition can impact inflammation, with the intake of certain food items increasing biomarkers for systemic inflammation thus, the objective of this research was to explore the relationship between inflammatory diet score measured by the Dietary Inflammatory index and all-cause mortality, cancer-specific mortality, and cancer recurrence among cancer survivors. Web of Science, Medline, …

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Intrahost Diversity Of Staphylococcus Aureus In Carriage Among Native Americans, Julia Webb Jan 2022

Intrahost Diversity Of Staphylococcus Aureus In Carriage Among Native Americans, Julia Webb

Electronic Theses and Dissertations, 2020-2023

Staphylococcus aureus (SA) is an opportunistic pathogen and a commensal member of the human microbiota that frequently colonizes the upper respiratory tract and skin. While SA can cause disease ranging from minor skin infections to life-threatening septicemia, it can also be carried asymptomatically. As carriage is the most significant risk factor for SA disease, surveillance is important for the prevention of outbreaks in vulnerable communities. Native Americans have a greater risk of infectious disease than the general US population, and Native Americans in the Southwestern United States have been shown to experience high rates of invasive SA disease. Here we …

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2022-2023 Halmos College Of Arts And Sciences Graduate Program Catalog, Nova Southeastern University Jan 2022

2022-2023 Halmos College Of Arts And Sciences Graduate Program Catalog, Nova Southeastern University

Halmos College of Arts and Sciences Course Catalogs

No abstract provided.

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Benchmarking Ultra-High Molecular Weight Dna Preservation Methods For Long-Read And Long-Range Sequencing, Hollis A. Dahn, Jacquelyn Mountcastle, Jennifer Balacco, Sylke Winkler, Iliana Bista, Anthony D. Schmitt, Olga Vinnere Pettersson, Giulio Formenti, Karen Oliver, Michelle Smith, Wenhua Tan, Anne Kraus, Stephen Mac, Lisa M. Komoroske, Tanya Lama, Andrew J. Crawford, Robert W. Murphy, Samara Brown, Alan F. Scott, Phillip A. Morin, Erich D. Jarvis, Olivier Fedrigo Jan 2022

Benchmarking Ultra-High Molecular Weight Dna Preservation Methods For Long-Read And Long-Range Sequencing, Hollis A. Dahn, Jacquelyn Mountcastle, Jennifer Balacco, Sylke Winkler, Iliana Bista, Anthony D. Schmitt, Olga Vinnere Pettersson, Giulio Formenti, Karen Oliver, Michelle Smith, Wenhua Tan, Anne Kraus, Stephen Mac, Lisa M. Komoroske, Tanya Lama, Andrew J. Crawford, Robert W. Murphy, Samara Brown, Alan F. Scott, Phillip A. Morin, Erich D. Jarvis, Olivier Fedrigo

Biological Sciences: Faculty Publications

Background: Studies in vertebrate genomics require sampling from a broad range of tissue types, taxa, and localities. Recent advancements in long-read and long-range genome sequencing have made it possible to produce high-quality chromosome-level genome assemblies for almost any organism. However, adequate tissue preservation for the requisite ultra-high molecular weight DNA (uHMW DNA) remains a major challenge. Here we present a comparative study of preservation methods for field and laboratory tissue sampling, across vertebrate classes and different tissue types. Results: We find that storage temperature was the strongest predictor of uHMW fragment lengths. While immediate flash-freezing remains the sample preservation gold …

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Genome-Wide Identification Of Wrky Transcription Factor Encoding Genes In Amborella Trichopoda Baill. (Amborellaceae), Bijaya Pradhan Jan 2022

Genome-Wide Identification Of Wrky Transcription Factor Encoding Genes In Amborella Trichopoda Baill. (Amborellaceae), Bijaya Pradhan

Electronic Theses and Dissertations

WRKY transcription factors (TFs) are DNA-binding proteins, which play important roles in managing plant stresses and regulating growth and development processes. The WRKY TF family has expanded significantly through genome/gene duplications in the plant evolutionary process. Although the WRKY TFs have been identified in hundreds of plant species, they are yet to be identified in Amborella trichopoda, a species that represents the most basal group of Angiosperms. The main objectives of this study were to conduct genome-wide identification of the WRKY gene family in A. trichopoda and to assess their homologs in Angiosperms. In this study, we identified …

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Effects Of Conservation Management Practices On Soil Health And Crop Yields In Eastern South Dakota, Alex Mclain Jan 2022

Effects Of Conservation Management Practices On Soil Health And Crop Yields In Eastern South Dakota, Alex Mclain

Electronic Theses and Dissertations

Conservation management practice adoption on agricultural land has increased in recent years due to increasing public and private investment. The anticipated impact of increasing conservation management practice adoption are reduced greenhouse gas emissions and improved soil, water, and air quality. Understanding how these conservation management practices affect agricultural producers economically is vital to properly incentivize these practices. The existing literature on how conservation management practices affect soil health and crop yields is mixed and generally has been conducted on experimental research stations. These studies may not fully account for the on-farm effects of conservation management practices. The objectives of this …

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Trace Mineral Source And Inclusion Level On Wean-To-Finish Pig Production, Marissa Larosae Jan 2022

Trace Mineral Source And Inclusion Level On Wean-To-Finish Pig Production, Marissa Larosae

Electronic Theses and Dissertations

Trace mineral requirements to optimize production for swine are not well defined, leading to excess trace mineral supplementation in swine diets and ultimately to excess trace minerals excreted in swine manure. Potential strategies to reduce the waste of excess trace minerals in diets include utilizing organic sources with higher bioavailability or reducing the overall trace mineral supplementation in the diet. Two studies were conducted in an effort to determine if utilizing organic trace minerals or reducing trace mineral inclusion into diets has an impact on overall performance measurements for nursery and grow-finish pigs, respectively. The first experiment utilized 1,144 weaned …

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E. Coli Persister Cell Survival And Rhizobia Attachment To Soybean Roots, Tanim Islam Jan 2022

E. Coli Persister Cell Survival And Rhizobia Attachment To Soybean Roots, Tanim Islam

Electronic Theses and Dissertations

The theme of this thesis revolves around how bacteria respond and thrive during stress. Chapters 1-3 are about how bacteria deal with life-threatening antibiotics. Chapter 4 covers new research on how bacteria can move from a stressful individual lifestyle (free-living bacteria) to initiating a symbiotic relationship with a plant (a less stressful lifestyle). In Chapter 1, I briefly summarize the current state of knowledge in the field of antibiotic resistance and persistence. In Chapter 2, I add to this knowledge by providing new insights into several antibiotics' potency and exploring the antibiotic Eagle effect. In Chapter 3, I use pyruvate …

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Identifying Adp-Ribosylation As The Biochemical Signal That Marks Dna-Protein Crosslinks For Sprtn-Dependent Proteolysis, Katelyn Hurley Jan 2022

Identifying Adp-Ribosylation As The Biochemical Signal That Marks Dna-Protein Crosslinks For Sprtn-Dependent Proteolysis, Katelyn Hurley

Electronic Theses and Dissertations

DNA-protein crosslinks (DPCs) form when proteins covalently attach to DNA. It is estimated that hundreds of DPCs form in our cells each day. Because these lesions are cytotoxic, mammalian cells have evolved multiple intricate repair systems to remove DPCs and restore genome integrity. One mechanism mammalian cells rely on for DPC repair is direct proteolysis by the metalloprotease, SPRTN. While it is known that SPRTN degrades a heterogenous array of DPCs, including both naturally occurring and chemically induced, how SPRTN selects DPCs amongst chromatin-associated proteins remains unknown. Our main objective is to determine how DPC repair is regulated. In Chapter …

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Snake Reciprocation In Terms Of Classical Conditioning: Scent And Auditory Stimuli, Zeina Y. Ghanem Jan 2022

Snake Reciprocation In Terms Of Classical Conditioning: Scent And Auditory Stimuli, Zeina Y. Ghanem

Undergraduate Research Awards

This study explores the classical conditioning of a snake in order to understand and interpret the physiological responses and behavior exhibited regarding experimental design. The conditioning process involves scent and auditory stimuli where the snake is exposed to running water sounds and a mouse scent. The purpose of this research study is to examine how the snake will later associate the scent of the mouse to the sound and how it would react when sound is the only stimuli administered. The type of snake species used was a young Brook’s Kingsnake. The snake was placed in a test tank and …

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Winter Wings: An Introduction To Environmental Education, Samuel G. Mothner Jan 2022

Winter Wings: An Introduction To Environmental Education, Samuel G. Mothner

Undergraduate Theses, Professional Papers, and Capstone Artifacts

No abstract provided.

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Comparing Mean & Peak Barbell Velocity During Traditional And Accentuated Eccentric Loaded Back Squats, Zach S. Schroeder, Lauren K. Marshall, Lea C. Katanick, Brookelyn A. Campbell, Conor J. Cantwell, Christopher B. Taber, Timothy J. Suchomel Jan 2022

Comparing Mean & Peak Barbell Velocity During Traditional And Accentuated Eccentric Loaded Back Squats, Zach S. Schroeder, Lauren K. Marshall, Lea C. Katanick, Brookelyn A. Campbell, Conor J. Cantwell, Christopher B. Taber, Timothy J. Suchomel

Exercise Science Faculty Publications

MV: There were statistically significant main effects present for both condition (p = 0.002; g = 0.10-0.23) and load (p < 0.001; g = 0.95-3.93). However, the condition x time interaction effect was not statistically significant (p = 0.259). • PV: There were statistically significant main effects present for both condition (p = 0.016; g = 0.11-0.23) and load (p < 0.001; g = 0.42-1.6), but there was no statistically significant condition x time interaction effect (p = 0.101). • Post hoc analysis indicated that there was a significant difference between MV (p = 0.006) and PV (p = 0.032) between the traditional and 100% AEL conditions. • Moderate effect sizes were found with MV between the traditional and 100% AEL conditions at both 70% CON (g = 0.55) and 80% CON (g = 0.70). • No practically significant differences were found for PV.

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The Role Of Edge Effects On Emerald Ash Borer Infestation And Forest Responses, Bronte Hoefer Jan 2022

The Role Of Edge Effects On Emerald Ash Borer Infestation And Forest Responses, Bronte Hoefer

Undergraduate Honors Theses

The emerald ash borer (EAB; Agrilus planipennis) is a buprestid beetle native to Asia, classified as an invasive species in North America. EAB infests trees of genus Fraxinus (ash) and has spread to 35 states since its introduction in the early to mid-1990s. Notably, EAB has the potential to functionally extirpate all native ash species in North America. Our study aims to characterize the ecological impacts of EAB infestation in the Roanoke Valley of Southwest Virginia, to quantify the impact of edge effects on EAB forest invasion and mortality of ash trees, as well as investigate the role that …

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