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Full-Text Articles in Life Sciences

Smokejumper Obituary: During, Kent J. (Missoula 1968), National Smokejumper Association Apr 2022

Smokejumper Obituary: During, Kent J. (Missoula 1968), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.


Skin Pigmentation And Arterial Stiffness In Young Health Black And White Adults, Zoe R. Lincoln Apr 2022

Skin Pigmentation And Arterial Stiffness In Young Health Black And White Adults, Zoe R. Lincoln

Honors College Theses

Cardiovascular disease (CVD) is currently the leading cause of death worldwide, killing over half a million people in the US every year. This issue is only becoming more prominent, as both the world and US population are experiencing increased rates of CVD risk factors such as hypertension, type 2 diabetes, and obesity. Black Americans specifically are experiencing increased rates of these risk factors, possibly due to lifestyle, socioeconomic, and genetic variables, ultimately leading to a higher prevalence of CVD in this population. One possible mechanism for this health disparity is racial differences in skin pigmentation, which can influence cardioprotective Vitamin …


Qualitative Analysis Of Colorectal Cancer Screening In Rural Nebraska, Kendra L. Ratnapradipa, Krishtee Napit, Jordan Ranta, Lady Beverly Luma, Danae Dinkel, Tamara Robinson, Laura Schabloske, Shinobu Watanabe-Galloway Apr 2022

Qualitative Analysis Of Colorectal Cancer Screening In Rural Nebraska, Kendra L. Ratnapradipa, Krishtee Napit, Jordan Ranta, Lady Beverly Luma, Danae Dinkel, Tamara Robinson, Laura Schabloske, Shinobu Watanabe-Galloway

Journal Articles

Compared to urban residents, rural populations are less likely to engage in colorectal cancer (CRC) screening. As part of a statewide cancer needs assessment, we aimed to elicit rural perspectives about CRC screening and resources. We conducted three focus groups with rural Nebraska cancer survivors and caregivers (N = 20) in Spring 2021 using a collective case study design. Participant awareness of and knowledge about CRC screening methods varied across focus groups; overall, 95% of participants had heard of colonoscopy. Participants were less familiar with fecal tests and had confusion about them. Colonoscopy was associated with negative perceptions regarding …


Canopy Arthropod Responses To Catastrophic Wind Disturbances In Gulf Coast And Caribbean Forests, Manoj Pandey Apr 2022

Canopy Arthropod Responses To Catastrophic Wind Disturbances In Gulf Coast And Caribbean Forests, Manoj Pandey

LSU Doctoral Dissertations

Hurricanes are major natural disturbances and integral components of forest disturbance regimes globally. The frequency and intensity of hurricanes are predicted to increase in the future due to global warming. The altered hurricane regime, along with direct effects of climate change on arthropod populations and communities, has the capacity to endanger the critical ecosystem processes and services provided by forest canopies. Therefore, it is crucial to understand the responses of forest fauna to disturbances such as hurricanes. This dissertation is aimed at understanding the short-term and long-term effects of hurricanes on canopy arthropods to improve predictions of the consequences of …


Trout Responses To Stocking Rates And River Discharge Within A Southeastern U.S. Hydropeaking Tailwater, Jonathan J. Spurgeon, Joseph Kaiser, Christy Graham, Steve Lochmann Apr 2022

Trout Responses To Stocking Rates And River Discharge Within A Southeastern U.S. Hydropeaking Tailwater, Jonathan J. Spurgeon, Joseph Kaiser, Christy Graham, Steve Lochmann

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

Freshwater fish populations often exist in systems characterized by novel ecological processes resulting from human alteration. Salmonid populations embedded within coldwater sections of warmwater rivers are spatially constrained by habitat availability. Tailwater fish contend with fluctuating river discharges and density-dependent processes associated with fish stocking and exploitation. Salmonid populations sustained through stocking versus natural reproduction may respond differently to changes in hydrologic patterns (e.g., hydropeaking) as well as declines in fish abundance. We assessed differences between stocked (Rainbow Trout Oncorhynchus mykiss) and naturalized (Brown Trout Salmo trutta) trout populations in Greers Ferry tailwater, Arkansas, regarding (1) spatial and …


Spr-5; Met-2 Maternal Reprogramming Cooperates With The Dream Complex To Regulate Developmental Cell Fates, Jazmin Dozier, Sandra Nguyen, Brandon Carpenter Apr 2022

Spr-5; Met-2 Maternal Reprogramming Cooperates With The Dream Complex To Regulate Developmental Cell Fates, Jazmin Dozier, Sandra Nguyen, Brandon Carpenter

Symposium of Student Scholars

Histone methylation is a post-transcriptional modification to the N-terminal tails of histone core proteins that regulates DNA accessibility, and consequently, gene expression. Like DNA, histone methylation can be inherited between generations, and is highly regulated during embryonic development. At fertilization, histone methylation must undergo maternal reprogramming to reset the epigenetic landscape in the new zygote. During maternal reprogramming of histone methylation in the nematode, C. elegans, H3K4me (a modification associated with active transcription) is removed by the H3K4 demethylase, SPR-5, and H3K9me (a modification associated with transcriptional repression) is subsequently added by the histone methyltransferase, MET-2. Recently, it was …


Effect Of Diet On Window Collision Rate Among Bird Species, Amberlee Cook, Courtney Linkous, Sarah Guindre-Parker, Adam Betuel Apr 2022

Effect Of Diet On Window Collision Rate Among Bird Species, Amberlee Cook, Courtney Linkous, Sarah Guindre-Parker, Adam Betuel

Symposium of Student Scholars

Every year, over 500 million birds collide fatally with man-made structures, with window collisions playing a significant role in causing these deaths. Our research analyzes how a species’ diet can affect their rates of collision with windows. To explore this question, we analyzed the most common food sources of 87 species of birds from window collision data in metro Atlanta. Our results showed that 77% of species from window collisions (or 67 species) were primarily insectivorous. This reliance on insects as a food source could lead to a lifestyle that tends to bring these bird species in closer proximity to …


Impact Of Fluctuating Insect Availability Levels On Parental Care Behavior In Insectivorous Birds, Cole Bourque Apr 2022

Impact Of Fluctuating Insect Availability Levels On Parental Care Behavior In Insectivorous Birds, Cole Bourque

Symposium of Student Scholars

Abstract Populations of aerially insectivorous birds are declining throughout North America. Urbanization may be indirectly contributing to this decline through its varying effects on populations of insects, an important food source in most insectivores' diet, especially those undergoing breeding efforts. How increasing urban sprawl and subsequent fluctuations in insect populations could impact various species at higher trophic levels is an important area of current study for future conservation endeavors. Certain habitats, with increased insect abundance, could facilitate higher provisioning rates and allow breeding parents to more effectively nourish their young. In addition, brooding and guarding behaviors in breeding birds may …


Ant-Lanta: Ant Diversity As A Proxy For Ecosystem Health, Sofia Cuenca Rojas, John Paul Hellenbrand, Clint Penick Apr 2022

Ant-Lanta: Ant Diversity As A Proxy For Ecosystem Health, Sofia Cuenca Rojas, John Paul Hellenbrand, Clint Penick

Symposium of Student Scholars

Ants are found across a wide range of habitat types and play a crucial role in supporting ecosystem health. Because of this ubiquity, ants are considered an indicator species – one whose diversity in an ecosystem can be used as a proxy for ecosystem health. Our study examines the presence of ants across an urban gradient in Atlanta to understand how urbanization may be affecting our local community inhabitants. A total of 48 Sites were organized into three groups: Urban Managed Land, Urban Park, and Urban Forest. Sites were grouped based on ground cover percentages. We used bait samples to …


Synthesis And Characterization Of A Novel Reaction-Based Azaborine Fluorescent Probe Capable Of Selectively Detect Carbon Monoxide Based On Palladium-Mediated Carbonylation Chemistry, Samuel Moore, Carl Jacky Saint-Louis Apr 2022

Synthesis And Characterization Of A Novel Reaction-Based Azaborine Fluorescent Probe Capable Of Selectively Detect Carbon Monoxide Based On Palladium-Mediated Carbonylation Chemistry, Samuel Moore, Carl Jacky Saint-Louis

Symposium of Student Scholars

Azaborines are fascinating compounds because they possess valuable properties such as photochemical stability, have high molar absorption coefficient and high fluorescent quantum yields, as well as large Stokes shifts and tunable absorption/emission spectra. Here, we designed, synthesized, and will examine a novel reaction-based azaborine fluorescent probe capable of selectively detect carbon monoxide (CO) based on palladium-mediated carbonylation chemistry. This novel azaborine fluorescent probe will exhibit high selectivity for CO and display a robust turn-on fluorescent response in the presence of CO in aqueous buffer solution.


Ketal-Azaborine Versus Ketal-Azaborine With A Spacer: Structural Effects On The Photophysical Properties Of Tunable Heteroaromatic Polycyclic Chromophores, Albert Campbell, Janiyah Riley, Samuel Moore, Albert Campbell Apr 2022

Ketal-Azaborine Versus Ketal-Azaborine With A Spacer: Structural Effects On The Photophysical Properties Of Tunable Heteroaromatic Polycyclic Chromophores, Albert Campbell, Janiyah Riley, Samuel Moore, Albert Campbell

Symposium of Student Scholars

Flat-structured heteroaromatic polycyclic compounds with extended conjugated π-systems such as azaborines are in high demand in the material and imaging technology markets because of their unique features such as simultaneous tunability of fluorescence color and intensity. We have designed, synthesized, and investigated a series of novel conjugated thermally stable ketal-azaborine chromophores that contain a phenyl ring as a spacer between electronic moieties and the ketal-azaborine core as easily tunable high-luminescent organic materials. We investigated the impact of the phenyl spacer on the ketal-azaborine unit. We examined the structural effects on their photophysical properties by incorporating electron –donating and –withdrawing substituents …


Azaborine Versus Azaborine With A Spacer: Structural Effects On The Photophysical Properties Of Tunable Azaborine Chromophores, Kaia Ellis, Janiyah Riley, Lyric Gordon, Janiyah Riley Apr 2022

Azaborine Versus Azaborine With A Spacer: Structural Effects On The Photophysical Properties Of Tunable Azaborine Chromophores, Kaia Ellis, Janiyah Riley, Lyric Gordon, Janiyah Riley

Symposium of Student Scholars

Azaborines are fascinating compounds because of their valuable and interesting optical properties making them suitable to be utilized in many optoelectronic devices. We have designed, synthesized, and investigated a series of novel conjugated thermally stable azaborine chromophores by incorporating a phenyl ring as a spacer linking the chromophore to different electronic moieties as easily tunable high-luminescent organic materials. We investigated the effect of the phenyl spacer on the azaborine unit. The substituent effects of different electronic moieties were investigated by the insertion of electron –withdrawing and –donating moieties to the phenyl spacer. We examined the role of the electron –donating …


Utilization Of Bioinformatics And Immunocytochemistry To Examine Gap Junction Expression In Breast Cancers Cells, Jasmine D. Carter, Giovanni Reyes, Abeeha K. Choudhary, Eric A. Albrecht Apr 2022

Utilization Of Bioinformatics And Immunocytochemistry To Examine Gap Junction Expression In Breast Cancers Cells, Jasmine D. Carter, Giovanni Reyes, Abeeha K. Choudhary, Eric A. Albrecht

Symposium of Student Scholars

Utilization of Bioinformatics and Immunocytochemistry to Examine Gap Junction Expression in Breast Cancers Cells.

Jasmine D. Carter1, Giovanni Reyes1, Abeeha Choudhary2 and Eric A. Albrecht1

Breast cancer is known for its diverse clinical classifications and expressing different levels of membrane proteins such as ion channels and gap junctions. This diversity allows more variations in cell polarization, which can lead to enhanced directional ion fluxes in certain breast cancer subtypes. We utilized the interactive web portal UALCAN to evaluate the gene expression data of gap junctions, ion exchange channels and cytoskeletal proteins in breast cancer …


New Ant In The Big City: Known Natural History Of Lasius Cf. Emarginatus In Its Native Range And Potential Impacts Of Recent Us Introduction, Samantha M. Kennett, Clint A. Penick Apr 2022

New Ant In The Big City: Known Natural History Of Lasius Cf. Emarginatus In Its Native Range And Potential Impacts Of Recent Us Introduction, Samantha M. Kennett, Clint A. Penick

Symposium of Student Scholars

New York City has been the site of introduction for some of North America’s most damaging invasive pests, from chestnut blight to the Asian long-horned beetle. Despite these cautionary examples, there has been no formal tracking of a newly introduced ant species, Lasius cf. emarginatus, which has quickly become among the most common species in the city. Sometime between the first ant diversity survey of New York City in 2006 and the second in 2011,L. cf. emarginatus was introduced and quickly became established in the most urban habitats with the highest human contact. In contrast to other urban …


Pseudomonas Aeruginosa Evades Predation By Myxococcus Xanthus, Sarah Joie Beauvais Apr 2022

Pseudomonas Aeruginosa Evades Predation By Myxococcus Xanthus, Sarah Joie Beauvais

Symposium of Student Scholars

Multidrug-resistant Pseudomonas aeruginosa causes an estimated 32,600 hospital-acquired-infections and 2,700 estimated deaths in the US in 2017(CDC). Myxococcus xanthus is a strain of myxobacteria that preys on Pseudomonas sp, through the production of antibiotics and digestive enzymes. In previous experiments, P. aeruginosa evaded predation, through an unknown mechanism. Using confocal microscopy, this research investigates if quorum sensing, a cell density-dependent signaling pathway, could be a factor in motility and evasion of M. xanthus. Liquid suspensions of log-phase PA01 were dyed with two fluorescent dyes: SYTO 9 for marking live cells and Propidium iodide (PI) for marking dead cells. …


Urban Surveying Of Bees And Wasps And Conscious Management, Sofia Castro, Grace Cope, Francis Mullan, Jaden Keys Apr 2022

Urban Surveying Of Bees And Wasps And Conscious Management, Sofia Castro, Grace Cope, Francis Mullan, Jaden Keys

Symposium of Student Scholars

Pollinators are integral to the functioning of urban ecosystems and agriculture yet face decline from habitat loss and fragmentation associated with urbanization. Recently, a growing number of urban universities have taken steps to ensure their campuses support pollinators. Kennesaw State University (KSU) is a semi-urban school located in the unique ecological area between the biodiversity hotspot of the Southeastern Appalachians and the urban space of Atlanta, Georgia. Before the present study, no survey had been conducted to determine what pollinators and associated floral resources exist on the school’s grounds. Thus, we present the first inventory of pollinators and the floral …


Characterization Of Erinacine-A, Justice Brakache Apr 2022

Characterization Of Erinacine-A, Justice Brakache

Symposium of Student Scholars

The wood-rot fungus known as the lion’s mane mushroom (H. erinaceus) has a long history of usage in ancient eastern medicine, noted for its health-boosting properties, particularly to neurological health. Claims include this mushroom’s ability to stimulate nerve growth as well as prevent the progression of neurodegenerative diseases such as dementia. Recent studies on the subject have shown promising data supporting these anecdotal claims, proving the ability of extracts from this mushroom to stimulate nerve growth factor (NGF) in human cells, among other beneficial findings. This study seeks to assess the effectiveness of the diterpenoid erinacine-A, present in H. …


Microbial Diversity And Community Structure In Sediments Associated With The Seagrass (Thallassia Testudinum) In Apalachicola Bay, Florida, Rahma Ahmed, Thomas Mcelroy, Troy Mutchler Apr 2022

Microbial Diversity And Community Structure In Sediments Associated With The Seagrass (Thallassia Testudinum) In Apalachicola Bay, Florida, Rahma Ahmed, Thomas Mcelroy, Troy Mutchler

Symposium of Student Scholars

Seagrass is an angiosperm which provides many ecosystem services in coastal areas, such as providing food, shelter and nurseries for many species, and decreasing the impact of waves on shorelines. A global assessment reported that 29% of known seagrass meadows are in a state of decline due to the effects of human activity. Seagrass is commonly found in shallow marine waters where they form meadows containing a microbiome that plays an important role in providing nutrients for seagrass growth, though little is known about the microorganisms within the seagrass meadow sediments. Our project collected sediments from seagrass meadows and adjacent …


Tissue-Specific Diversity Of The Muscleblind Expression In Adult Flies., Davron Hanley, Anton Bryantsev Apr 2022

Tissue-Specific Diversity Of The Muscleblind Expression In Adult Flies., Davron Hanley, Anton Bryantsev

Symposium of Student Scholars

Department of Molecular and Cellular Biology, Kennesaw State University

The muscleblind (mbl) family of RNA-binding proteins regulates alternative splicing, determining mRNA transcript composition for various types of tissue, and has been implicated in myotonic dystrophy. The mbl gene is subject to alternative splicing in Drosophila, leading to multiple isoforms, and has several paralogs in humans. Mbl proteins vary significantly in length, although the significance of such diversity and the role of specific isoforms have not been fully explored.

Using immunofluorescence microscopy and polyclonal serum, we analyzed Mbl protein expression across adult Drosophila tissues. Mbl was detected in …


Future In Phage Therapy Against Antibiotic-Resistant Bacteria​, Elizabeth Breckenridge, Sandra Arias, Bonnie Butter Apr 2022

Future In Phage Therapy Against Antibiotic-Resistant Bacteria​, Elizabeth Breckenridge, Sandra Arias, Bonnie Butter

Research and Creativity Symposium

The genus Bacillus is a medically important genus because several species cause disease like cereus and anthracis, that involves several species within it. We chose B. thuringiensis, a non pathogenic species of Bacillus, as our host as it is very abundant in the environment and therefore it is easy to isolate phages. The University of Mary Washington Class of 2021-2022 isolated a total of eight phages. The phages were photographed using a Transmission Electron Microscope to determine their morphotype. They were further characterized by host range analysis showed that KoopaTroopa grew on other Bacillus species such as B. cereus. B. …


Myokine Expression In A Myotonic Dystrophy Type 1 Cell Culture Model, Abigail Vorsteg Apr 2022

Myokine Expression In A Myotonic Dystrophy Type 1 Cell Culture Model, Abigail Vorsteg

Research and Creativity Symposium

Myotonic dystrophy type 1 (DM1) is a multisystemic disease characterized by muscle weakening and wasting. DM1 is the most commonly diagnosed adult-onset muscular dystrophy, and skeletal muscle wasting is responsible for 60% of DM1 related mortality, although the mechanism responsible for the DM1 skeletal muscle wasting phenotype has not been concretely identified. DM1 is caused by expansion of CUG repeats in the 3′ untranslated region of the DMPK gene. Pervious research has suggested that myokines, signaling molecules typically involved in cell-cell communication, play a role in muscle wasting. Additionally, gene expression analysis of a mouse DM1 model identified elevated expression …


The Effects Of Voluntary Physical Exercise On Hedonic Drive And Hypothalamic Orexin In Cd-1 Mice, Katie Warlick Apr 2022

The Effects Of Voluntary Physical Exercise On Hedonic Drive And Hypothalamic Orexin In Cd-1 Mice, Katie Warlick

Research and Creativity Symposium

Orexin, also referred to as hypocretin, is a peptide produced in the hypothalamus that regulates many physiological and behavioral processes, including sleep, wakefulness, metabolism, thermoregulation, and reward (Chieffi et al., 2017). The multiple mechanisms of orexin stem from the neural circuit or nucleus where it is synthesized or released. Orexin produced in the perifornical and dorsomedial hypothalamus projects to the amygdala, and is most heavily associated with arousal and wakefulness, whereas orexin produced in the lateral hypothalamus (LH) projects to the mesolimbic pathway and is associated with hedonic behavior, as it influences the Ventral Tegmental Area (VTA) and the Nucleus …


Grumio Bacteriophage Genome Annotation, Celeste Lockwood Apr 2022

Grumio Bacteriophage Genome Annotation, Celeste Lockwood

Research and Creativity Symposium

Bacteriophages, or phages, are virus particles which are only capable of infecting bacterial cells (Clokie et al.). These phages are of interest as a potential replacement for antibiotic therapies in cases of drug resistant bacterial infections (Sulakyelidz et al. 2001). One such phage, Grumio, was discovered and isolated at the University of Mary Washington. As a recently discovered phage there was very little known about it, such as the specific sequences of DNA responsible for its infection of certain strains of bacteria. By analyzing this genetic material, the genomic sequences responsible for the phages ability to infect certain strains of …


Essential Oils As Bacterial Disinfectants, Chandler Carlson, Julia Rizzo Apr 2022

Essential Oils As Bacterial Disinfectants, Chandler Carlson, Julia Rizzo

Research and Creativity Symposium

Essential oils have become quite popular in natural medicine and their uses as an antibacterial household cleaner have been touted. We investigated how essential oils compared to bleach when used as disinfectants. Previously, we examined eight essential oils and two recipes (mixtures of oils) from Art Naturals for bacterial inhibition and found that six oils and both recipes consistently inhibited bacterial growth. In this study, we tested bacterial inhibition of individual oils, combinations/recipes of oils, exposure time to oils, concentrations of an oil, and build-up/toxicity of oil residues from doTERRA. Escherichia coli was plated onto McConkey agar as a lawn …


Biophysical Factors Control Invasive Grass Hot Spots In The Mojave Desert, Tanner Corless Smith Apr 2022

Biophysical Factors Control Invasive Grass Hot Spots In The Mojave Desert, Tanner Corless Smith

Theses and Dissertations

The social, economic, and ecological costs of plant invasions are vast, through their ability to alter ecosystem structure and function. Invasive annual grasses are a nuisance in the American Southwest through promotion of the grass-fire cycle. Annual grasses such as Bromus rubens, Bromus tectorum, Schismus barbatus, and Schismus arabicus have invaded the Mojave Desert and increased fire occurrence, thus it is important to identify and characterize the areas where persistent invasion has occurred and subsequently fire risk is increased by understanding the distribution of these invasive grasses. Previous plot and landscape-scale research has revealed anthropogenic and biophysical correlates with the …


Please Keep Plastics Out Of My Lagoon!, Linda Walters Apr 2022

Please Keep Plastics Out Of My Lagoon!, Linda Walters

CEELAB Children's Books

Everyone is talking about plastic pollution. In this book for young audiences, we provide information on plastic pollution, including microplastics. We describe some of the many animals found in our favorite estuary, the Indian River Lagoon, that are impacted by plastics. This book asks young readers to pick the items they want to see in their lagoon, "This animal friend or that harmful piece of plastic?"


In The Face Of Climate Change, Does Human Trampling Affect Dune Resilience And Alter Ecosystem Services?, Alexandra O. Findlay Apr 2022

In The Face Of Climate Change, Does Human Trampling Affect Dune Resilience And Alter Ecosystem Services?, Alexandra O. Findlay

Honors College Theses

Sand dunes play a valuable role on the coastline supporting unique native species and protecting beach communities. The City of Tybee Island, Georgia, USA has undergone extensive dune restoration to expand and rehabilitate its shoreline to better defend the town against the increasing frequency of hurricanes and storm surge. The project included the recovery of existing dune structures and construction of new dunes filled with sand pumped from offshore and vegetated with a variety of native species. To analyze the impact of human trampling on dune vegetation occurring adjacent to footpaths and crossovers in new and established dunes, we measured …


Using Movement To Infer Critical Life History Events In Mule Deer: Parturition And Natal Dispersal, Tabitha A. Hughes Apr 2022

Using Movement To Infer Critical Life History Events In Mule Deer: Parturition And Natal Dispersal, Tabitha A. Hughes

Theses and Dissertations

The advent of GPS tracking technology has revolutionized the field of wildlife research. The ability to obtain fine-scale location data from collared animals allows for increased understanding of life-history events that have previously been difficult to research. An excellent candidate species for telemetry-based research is mule deer (Odocoileus hemionus). Mule deer are an important species economically due to their position as a harvested species. Additionally, they play an important role in the ecosystems they occupy; therefore information regarding important life history events would improve conservation and management efforts for this species. Our objectives were to use GPS tracking technology to …


Teaching Medicinal Plants Used By Native Americans, Amadea Pourier, Dillon Nelson, Wiyaka Pomarleau, Kay Cutler, Madhav P. Nepal Apr 2022

Teaching Medicinal Plants Used By Native Americans, Amadea Pourier, Dillon Nelson, Wiyaka Pomarleau, Kay Cutler, Madhav P. Nepal

iLEARN Teaching Resources

In this lesson, students will also be able to identify four medicinal plants, describe their characteristics and discuss medicinal uses. Students will use their senses to experience the uses of these medicinal plants. The plants highlighted in this lesson are Chokecherry Tree, Prairie Sage, Lead Plant, and Purple Cornflower. The senses used may consist of smelling the aroma of sage, burning the root of the purple coneflower, or tasting the infusion of the Lead Plant.


Localized Heat Therapy Improves Mitochondrial Function In Human Skeletal Muscle, Erik D. Marchant Apr 2022

Localized Heat Therapy Improves Mitochondrial Function In Human Skeletal Muscle, Erik D. Marchant

Theses and Dissertations

Physical activity results in various types of stress in skeletal muscle including energetic, oxidative, and heat stress. Acute exposure to stress impairs skeletal muscle mitochondrial function. In contrast, chronic intermittent exposure to mild stress through exercise training results in increased mitochondrial content and respiratory capacity. While oxidative and energetic stress have received much attention regarding their long-term effect on skeletal muscle mitochondria, heat stress is not well understood. The purpose of this work was to investigate the effects of localized heat therapy on human skeletal muscle mitochondria, and to compare these effects to those of high-intensity interval exercise training. To …