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Articles 50821 - 50850 of 255928
Full-Text Articles in Life Sciences
Study On Visual Judgment Method Of Fermentation Degree In Industrialized Bread Production Based On Bp Neural Network, Zhao Chun, Chen Xue-Yong, Wu Shao-Shuang, Pang Jie
Study On Visual Judgment Method Of Fermentation Degree In Industrialized Bread Production Based On Bp Neural Network, Zhao Chun, Chen Xue-Yong, Wu Shao-Shuang, Pang Jie
Food and Machinery
Objective:A BP neural network model was established to accurately determine the maturity of dough fermentation.Methods:Used machine vision technology to collect and process the pictures of bread fermentation process, obtained the quantitative information of the pictures, and a prediction model was established for bread fermentation degree based on BP neural network. Taking the time, area, instantaneous velocity, expansion rate, gray value energy, gray value relationship, gray value uniformity and gray value contrast as the input neurons, the regression model of relevant parameters was established.Results:The correlation between the above characteristic parameters and the fermentation process of bread …
Liquor Blending Control Based On Variable Universe Fuzzy-Smith Modle, Zhou Yong-Shuai, Tuo Xian-Guo, Han Qiang, Liu Xin
Liquor Blending Control Based On Variable Universe Fuzzy-Smith Modle, Zhou Yong-Shuai, Tuo Xian-Guo, Han Qiang, Liu Xin
Food and Machinery
Objective:Meets the requirements of no overshoot in the response of the liquor blending control system, and eliminate the influence of system time lag on its control effect.Methods:An algorithm of liquor blending control based on variable universe fuzzy-Smith was proposed. Analyzed the control process and characteristics of the system and establish an approximate mathematical model. Quoting Smith predictor to compensate for the time lag in the system, utilizing the characteristics of fuzzy control to solve the problem of inaccurate system mathematics model, combined with the variable universe method to eliminate the shortcomings of conventional fuzzy control method with …
Study On Preparation Of High Purity 1,3-Diglyceride From Yanhuang Beef Tallow, Qu Ke-Xin, Gao Qing-Shan, Yao Hui-Yao, Liu Long-Long, Zhang Hua, Li Xuan-Jun
Study On Preparation Of High Purity 1,3-Diglyceride From Yanhuang Beef Tallow, Qu Ke-Xin, Gao Qing-Shan, Yao Hui-Yao, Liu Long-Long, Zhang Hua, Li Xuan-Jun
Food and Machinery
Objective:This study aimed to increase the added value of Yanbian yellow cattle fat.Methods:Using immobilized lipase Lipozyme RM IM as a catalyst, and tallow fatty acid ethyl ester (self-made by ethanol hydrolysis) and glycerol as raw materials to prepare 1,3-diglyceride, using nuclear magnetic resonance to investigate the effect of lipase addition, substrate molar ratio, reaction time and reaction temperature on the content of 1,3-diglyceride in the crude reaction mixture. The changes in fatty acid composition of the tallow and diglyceride products was clarified before and after the alcoholysis and transesterification.Results:The best conditions for the synthesis of …
Study On Microwave Heating On Nutrition And Flavor Composition Of Crayfish, Xu Wen-Si, Yang Qi-Fu, Zhao Zi-Long, Yan Ming-Zhu, Wu Shuang-Qing, Wang Yan, Yang Pin-Hong
Study On Microwave Heating On Nutrition And Flavor Composition Of Crayfish, Xu Wen-Si, Yang Qi-Fu, Zhao Zi-Long, Yan Ming-Zhu, Wu Shuang-Qing, Wang Yan, Yang Pin-Hong
Food and Machinery
Objective:The effect of microwave heating on nutrition and flavor composition of crayfish was investigated.Methods:After pre-treatment, the nutrition and flavor changes of crayfish without microwave treatment, 210 W microwave and 350 W microwave treatment for 5 min were analyzed respectively.Results:The results showed that low power microwave treatment did not significant affect the crayfish water content, which was obvious loss under the condition of 350 W microwave. In dry samples, the microwave power had no significant effect in crude ash, while the total sugar and crude fat was affected with a decrease tendency. However, the microwave power …
Research Progress On Detection Methods Of Chemically Synthesized Coccidiostat Residues, Pang Xing-Hao, Hu Xiao-Fei, Xing Yun-Rui, Sun Ya-Ning, Wang Yao
Research Progress On Detection Methods Of Chemically Synthesized Coccidiostat Residues, Pang Xing-Hao, Hu Xiao-Fei, Xing Yun-Rui, Sun Ya-Ning, Wang Yao
Food and Machinery
In this review, the detection Methods of chemically synthesized coccidiostat residues were summarized, with emphasis on the research progress of high performance liquid chromatography-tandem mass spectrometry, enzyme-linked immunosorbent assay, immunochromatographic test paper, surface enhanced Raman spectroscopy and other Methods. The development status and trend of detection Methods were discussed, and the future development direction was prospected.
Nabat Ml: Utilizing Deep Learning To Enable Crowdsourced Development Of Automated, Scalable Solutions For Documenting North American Bat Populations, Ali Khalighifar, Benjamin S. Gotthold, Erin Adams, Jenny Barnett, Laura O. Beard, Eric R. Britzke, Paul A. Burger, Kimberly Chase, Zackary Cordes, Paul M. Cryan, Emily Emily, Christopher T. Fill, Scott E. Gibson, G. Scott Haulton, Kathryn M. Irvine, Lara S. Katz, William L. Kendall, Christen A. Long, Oisin Mac Aodha, Tessa Mcburney, Sara Mccarthy, Matthew W. Mckown, Joy O'Keefe, Lucy D. Patterson, Kristopher A. Pitcher, Matthew Rustand, Jordi L. Segers, Kyle Seppanen, Jeremy L. Siemers, Christian Stratton, Bethany R. Straw, Theodore J. Weller, Brian E. Reichert
Nabat Ml: Utilizing Deep Learning To Enable Crowdsourced Development Of Automated, Scalable Solutions For Documenting North American Bat Populations, Ali Khalighifar, Benjamin S. Gotthold, Erin Adams, Jenny Barnett, Laura O. Beard, Eric R. Britzke, Paul A. Burger, Kimberly Chase, Zackary Cordes, Paul M. Cryan, Emily Emily, Christopher T. Fill, Scott E. Gibson, G. Scott Haulton, Kathryn M. Irvine, Lara S. Katz, William L. Kendall, Christen A. Long, Oisin Mac Aodha, Tessa Mcburney, Sara Mccarthy, Matthew W. Mckown, Joy O'Keefe, Lucy D. Patterson, Kristopher A. Pitcher, Matthew Rustand, Jordi L. Segers, Kyle Seppanen, Jeremy L. Siemers, Christian Stratton, Bethany R. Straw, Theodore J. Weller, Brian E. Reichert
Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications
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Bats play crucial ecological roles and provide valuable ecosystem services, yet many populations face serious threats from various ecological disturbances. The North American Bat Monitoring Program (NABat) aims to use its technology infrastructure to assess status and trends of bat populations, while developing innovative and community-driven conservation solutions.
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Here, we present NABat ML, an automated machine-learning algorithm that improves the scalability and scientific transparency of NABat acoustic monitoring. This model combines signal processing techniques and convolutional neural networks (CNNs) to detect and classify recorded bat echolocation calls. We developed our CNN model with internet-based computing resources (‘cloud environment’), and …
Using Dietary Additives To Improve Palatability Of Diets Containing Single‐Cell Protein From Methanotrophic Bacteria In Yellowtail Kingfish (Seriola Lalandi) Diets, Luke Pilmer, Lindsey Woolley, Alan J. Lymbery, Michael Salini, Gavin Partridge
Using Dietary Additives To Improve Palatability Of Diets Containing Single‐Cell Protein From Methanotrophic Bacteria In Yellowtail Kingfish (Seriola Lalandi) Diets, Luke Pilmer, Lindsey Woolley, Alan J. Lymbery, Michael Salini, Gavin Partridge
Fisheries Research Articles
Single-cell protein (SCP) derived from methanotrophic bacteria has significant potential as a fishmeal alternative in aquafeeds. However, SCP has known palatability issues, to overcome these issues tuna hydrolysate and garlic powder were tested as palatability enhancers against basal diets without these additives. This study tested the inclusion of SCP at four dietary levels of 0%, 10%, 20% and 30%, representing 0%, 25%, 50% and 75% fishmeal replacement in juvenile yellowtail kingfish (Seriola lalandi) (YTK) diets. YTK were fed these diets in triplicate over 35 days. Compared with the control diet, fish fed the SCP10% diet ate less feed, …
Genomic Analysis And Therapeutic Development Of Bacteriophages To Treat Bacterial Infections And Parasitic Infestations, Daniel W. Thompson
Genomic Analysis And Therapeutic Development Of Bacteriophages To Treat Bacterial Infections And Parasitic Infestations, Daniel W. Thompson
Theses and Dissertations
Microbiomes are an extremely vast and complex network of microorganisms. Bacteriophages are a key factor in the microbial health of an ecological system and impact the evolution of pathogenic bacterial strains. Bacteria and the phages that infect them have an intricate relationship due to the dependency on the bacterial host for phage replication, the ability of the phage to lyse and kill its host, and the horizontal gene transfer between the host and phage. This thesis aimed to understand how bacteria and the bacteriophages that infect them impact an ecological system, with a focus on disease states. By analyzing all …
Adulteration Model Establishment Of Camellia Oil Based On Aroma Components Extracted From Camellia Oil And Its Application, Chen Ze-Ming, Zhao Xin-Xin, Zhu Xiao-Yang, Zhou Bo, Zhong Hai-Yan
Adulteration Model Establishment Of Camellia Oil Based On Aroma Components Extracted From Camellia Oil And Its Application, Chen Ze-Ming, Zhao Xin-Xin, Zhu Xiao-Yang, Zhou Bo, Zhong Hai-Yan
Food and Machinery
Objective:This study aimed to solve the problem of quantitative detection of adulteration of extracted camellia seed oil into pressed camellia seed oil.Methods:HS-SPME-GC-MS was used to determine and analyze the key aroma components of refined camellia oil and three kinds of extracted camellia oil with essence.The relative contents of aroma components in 4 kinds of original camellia oil and 10 kinds of roasted camellia oil were compared with those in extracted camellia oil. Fisher discriminant analysis was carried out with the characteristic data of aroma components in extracted camellia oil, and LDA model was established.Results:The key …
Prior Exposure To Microcystin Alters Host Gut Resistome And Is Associated With Dysregulated Immune Homeostasis In Translatable Mouse Models, Punnag Saha, Dipro Bose, Vitalii Stebliankin, Trevor Cickovski, Ratanesh K. Seth, Dwayne E. Porter Ph.D., Bryan W. Brooks, Kalai Mathee, Giri Narashimhan, Rita Colwell, Geoffry Ivan Scott Ph.D., Saurabh Chatterjee Ms., Ph.D
Prior Exposure To Microcystin Alters Host Gut Resistome And Is Associated With Dysregulated Immune Homeostasis In Translatable Mouse Models, Punnag Saha, Dipro Bose, Vitalii Stebliankin, Trevor Cickovski, Ratanesh K. Seth, Dwayne E. Porter Ph.D., Bryan W. Brooks, Kalai Mathee, Giri Narashimhan, Rita Colwell, Geoffry Ivan Scott Ph.D., Saurabh Chatterjee Ms., Ph.D
Faculty Publications
A strong association between exposure to the common harmful algal bloom toxin microcystin and the altered host gut microbiome has been shown. We tested the hypothesis that prior exposure to the cyanotoxin microcystin-LR may alter the host resistome. We show that the mice exposed to microcystin-LR had an altered microbiome signature that harbored antibiotic resistance genes. Host resistome genotypes such as mefA, msrD, mel, ant6, and tet40 increased in diversity and relative abundance following microcystin-LR exposure. Interestingly, the increased abundance of these genes was traced to resistance to common antibiotics such as tetracycline, macrolides, glycopeptide, and aminoglycosides, crucial for modern-day …
Quantifying Protein Quality To Understand Protein Homeostasis (Supplemental Data), Hsien-Jung Lavender Lin
Quantifying Protein Quality To Understand Protein Homeostasis (Supplemental Data), Hsien-Jung Lavender Lin
ScholarsArchive Data
This data set includes the supplementary data for chpaters 3 and 4 in the dissertation Quantifying Protein Quality to Understand Protein Homeostasis. It includes various excel worksheets that were used to generate the data reported in the dissertation. We make this data available to the public so anyone who wants to reproduce the results has the resources and access to other perspectives that weren't discussed in depth in the dissertation. Chapter 3 used mass-spectrometry to quantify the surface accessibility differences in human serum albumin (HSA)between patients with and without rheumatoid arthritis (RA). We found certain residues are less reactive …
Aligning The American Health Information Management Association Entry-Level Curricula Competencies And Career Map With Industry Job Postings: Cross-Sectional Study, Robert Hoyt, Karima Lalani, Connie Renda, Rebecca B Reynolds
Aligning The American Health Information Management Association Entry-Level Curricula Competencies And Career Map With Industry Job Postings: Cross-Sectional Study, Robert Hoyt, Karima Lalani, Connie Renda, Rebecca B Reynolds
Faculty, Staff and Student Publications
BACKGROUND: The field of health information management (HIM) focuses on the protection and management of health information from a variety of sources. The American Health Information Management Association (AHIMA) Council for Excellence in Education (CEE) determines the needed skills and competencies for this field. AHIMA's HIM curricula competencies are divided into several domains among the associate, undergraduate, and graduate levels. Moreover, AHIMA's career map displays career paths for HIM professionals. What is not known is whether these competencies and the career map align with industry demands.
OBJECTIVE: The primary aim of this study is to analyze HIM job postings on …
Biological Flora Of Coastal Wetlands: Sporobolus Cynosuroides (L.) P.M. Peterson & Saarela, Richard Stalter, Robert I. Lonard
Biological Flora Of Coastal Wetlands: Sporobolus Cynosuroides (L.) P.M. Peterson & Saarela, Richard Stalter, Robert I. Lonard
School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)
Sporobolus cynosuroides (L.) P.M. Peterson & Saarela¼Spartina cynosuroides (L.) Roth is a temperate zone rhizomatous grass that often is a dominant species in coastal brackish marshes on the Gulf coast and Atlantic coasts of the United States where salinity ranges from 0 to 10 psu. Sporobolus cynosuroides (L.) P.M. Peterson & Saarela ¼ Spartina cynosuroides (L.) Roth is usually absent where salinity values are .12 psu. Sporobolus cynosuroides occurs in coastal habitats characterized by infrequent tidal flooding and moderate nutrient levels. Also known as big cordgrass, it may account for net productivity in high marshes that rivals productivity of Sporobolus …
Determination And Correlation Analysis Of Tobacco Non-Volatile Organic Acids And Ph, Piao Yong-Ge, Zhang Jia-Bao, Cui Cheng-Zhe, Liu You-Jie, Li He-Lin, Li Rui-Li, Zhang Jun-Song
Determination And Correlation Analysis Of Tobacco Non-Volatile Organic Acids And Ph, Piao Yong-Ge, Zhang Jia-Bao, Cui Cheng-Zhe, Liu You-Jie, Li He-Lin, Li Rui-Li, Zhang Jun-Song
Food and Machinery
Objective:To explore the effects of organic acids on tobacco pH and flue gas pH.Methods:34 kinds of single-grade tobacco and 11 kinds of finished cigarettes were taken as the research objects, and their non-volatile organic acids, tobacco pH, and the pH of mainstream smoke total particulate matter were measured respectively. Grey correlation analysis and principal component analysis were used to analyze the correlation between organic acids and pH.Results:The results of grey correlation analysis show that oxalic acid, palmitic acid, malic acid and oleic acid have a relatively large influence on the pH of single-grade tobacco; Palmitic …
Research On Rapid Prediction Model Of Rice Moisture Content Based On Near Infrared Spectroscopy, Lu Du, Tang Jian-Bo, Jiang Tai-Ling, Chen Zhong-Ai, Pan Mu
Research On Rapid Prediction Model Of Rice Moisture Content Based On Near Infrared Spectroscopy, Lu Du, Tang Jian-Bo, Jiang Tai-Ling, Chen Zhong-Ai, Pan Mu
Food and Machinery
Objective:In order to established a non-destructive, rapid and efficient method for detecting the moisture content of rice. Methods:This study, 161 rice samples were collected from 5 different regions were studied by near infrared spectroscopy combined with stoichiometry. By eliminating abnormal spectra and preprocessing the spectra, the prediction model of rice moisture content was established by partial least squares regression. Results:15 abnormal spectrum samples were eliminated using the method of principal component analysis combined with mahalanobis distance. The best spectral pretreatment was to eliminate the constant offset. The prediction model R2CAL established in the training set was 0.994 …
Gas Mixing System Of Modified Atmosphere Packaging Based On Ideal Gas Law And DaltonʼS Law Of Partial Pressure, Zhang Han-Nan, Kang Ning-Bo, He Jian-Guo, Liu Gui-Shan, Chen Shou-Tao, Sun You-Rui, Chen Ya-Peng
Gas Mixing System Of Modified Atmosphere Packaging Based On Ideal Gas Law And DaltonʼS Law Of Partial Pressure, Zhang Han-Nan, Kang Ning-Bo, He Jian-Guo, Liu Gui-Shan, Chen Shou-Tao, Sun You-Rui, Chen Ya-Peng
Food and Machinery
Objective:In order to solve the problem of poor stability, high cost and small gas flow of ternary gas mixing equipment.Methods:A ternary gas mixing system based on the ideal gas law and Daltonʼs law of partial pressure was proposed, and the system calculated errors and adjusted parameters by the designed algorithm, and adopted the connection of cylinder, sensor and so on.Results:After adjusting the mixing according to the relative deviation, the average relative deviation of the gas concentration of CO2and O2was 0.86% and 0.75% respectively, and the gas concentration accuracy met the technical requirements of <1%, and …
Research On Tomato Maturity Detection Method Based On Machine Vision And Electronic Nose Fusion, Wang Jun-Ping, Xu Gang
Research On Tomato Maturity Detection Method Based On Machine Vision And Electronic Nose Fusion, Wang Jun-Ping, Xu Gang
Food and Machinery
Objective:To explore the application ability of machine vision and electronic nose fusion method in fruit and vegetable maturity detection, and realize the detection of different maturity of tomato.Methods:Based on machine vision and electronic nose acquisition system, a tomato maturity detection method based on multi-source information fusion was proposed. Based on 6 color features screened by machine vision and 10 odor features screened by electronic nose, the least squares support vector machine model for tomato maturity detection was established. The feasibility of this method is verified by comparing the fusion method with single method.Results:Compared with the …
Egg Crack Image Detection Method Based On Improved Grasshopper Optimization Algorithm And Canny Operator, Tu Wei-Hu, Cai Ling-Xia, Li Xue-Jun
Egg Crack Image Detection Method Based On Improved Grasshopper Optimization Algorithm And Canny Operator, Tu Wei-Hu, Cai Ling-Xia, Li Xue-Jun
Food and Machinery
Objective:In order to improve the detection effect of egg linear and reticular cracks.Methods:As the low convergence efficiency of Grasshopper optimization algorithm (GOA) in solving high-dimensional complex optimization problems, an improved fuzzy cmeans algorithm (FCM) was designed to classify locust population. The adaptive extreme value reverse learning and coding mutation update mechanism were designed to expand the depth search space and global optimization ability of the algorithm. The improved GOA was used to optimize the parameters, and the improved canny operator was used for egg crack detection.Results:The results showed that the missed detection rates of egg …
Preparation And Response Surface Optimization Of Cinnamaldehyde Liposome By Ethanol Injection, Chang Da-Wei, Yan Jin, Lei Qi, Wang Hu-Xuan, Wang Huan
Preparation And Response Surface Optimization Of Cinnamaldehyde Liposome By Ethanol Injection, Chang Da-Wei, Yan Jin, Lei Qi, Wang Hu-Xuan, Wang Huan
Food and Machinery
Objective:Cinnamaldehyde was encapsulated in the liposome.Methods:Cinnamaldehyde was selected as the research object and the cinnamaldehyde liposomes were prepared by ethanol injection method. The effects of phospholipid concentration, ratio of phospholipid to cholesterol, ratio of phospholipid to cinnamaldehyde and injection velocity on the encapsulation efficiency, particle size and polydispersity index (PDI) of cinnamaldehyde liposomes were investigated, and the process was optimized by response surface method with the encapsulation efficiency as the index.Results:The optimum preparation conditions of cinnamaldehyde liposomes were as follows: the phospholipid concentration was 2.69 mg/mL, the ratio of phospholipid to cinnamaldehyde was 6.73, and …
Dynamic Target Grasping Control Method Of Food Sorting Robot Based On Improved Particle Swarm Optimization, Wang Min, Jiang Jin-Wei, Cao Yan-Tao
Dynamic Target Grasping Control Method Of Food Sorting Robot Based On Improved Particle Swarm Optimization, Wang Min, Jiang Jin-Wei, Cao Yan-Tao
Food and Machinery
Objective:To solve the problems of unstable grasping operation and low sorting efficiency of sorting robot in food production line.Methods:Based on the architecture of high-speed parallel food sorting robot, a multi-objective motion optimization strategy based on improved particle swarm optimization algorithm was proposed for the dynamic target grasping control method of food sorting robot. By coordinating the grasping sequence and sorting trajectory, the shortest path model was established. Establish the mechanism stability optimization model with the end acceleration, and optimized the target by improving the particle swarm optimization algorithm.Results:Through experimental verification, when the conveying speed was …
Design And Experiment Of Coconut Meat Digge, Zeng Wen-Zhang, Fan Jun-Qing, Zhang Bao-Zhen
Design And Experiment Of Coconut Meat Digge, Zeng Wen-Zhang, Fan Jun-Qing, Zhang Bao-Zhen
Food and Machinery
Objective:To solve the problems of low automation level and low security of coconut meat digging machine in China.Methods:The coconut meat extraction device was designed by using several mutually fitting curved blade, electric push rod, compression spring, crank and rocker mechanism, pressure sensor and other mechanisms, and the automatic control system was designed according to the process of coconut meat digger, the coconut meat digger run stably.Results:The experimental device of coconut meat extraction can operate safely and stably, when the rotating motor speed was 130 r/min and the lifting motor speed was 150 r/min, and the …
Characterization, Rheological Study And Antioxidant Activities Of Polysaccharide From Azolla, Yao Yue-Hua, Tang Ning, Ying Xi-Rui, Ying Chao-Yang, Cheng Yong-Qiang
Characterization, Rheological Study And Antioxidant Activities Of Polysaccharide From Azolla, Yao Yue-Hua, Tang Ning, Ying Xi-Rui, Ying Chao-Yang, Cheng Yong-Qiang
Food and Machinery
Objective:The study aimed to research the characterization, rheological properties and antioxidant activities of polysaccharide from Azolla.Methods:The polysaccharide was obtained through hot water extraction. The molecular weight, monosaccharide composition, microstructure, rheological properties and antioxidant activities were analyzed by gel-permeation chromatography (GPC), FT-IR spectrometric, scanning electron microscopy (SEM) and so on.Results:The polysaccharide from Azolla containing two groups of molecular weight (2 338.00 and 1.60 kDa) was an acidic heteropolysaccharide, which was mainly composed of mannose, glucuronic acid, galactose, xylose and glucose. The sample had the typical absorption peaks of polysaccharide, which connection mode of heterocephalic carbon was …
Enzymatic Preparation And Activity Study Of Rice Bran Protein-Derived Ace Inhibitory Peptides, Zhang Ling-Yu, Miao Jian-Yin, Cao Yu, Dai Wei-Jie, Liu Guo, Li Zhen-Wei, Cao Yong
Enzymatic Preparation And Activity Study Of Rice Bran Protein-Derived Ace Inhibitory Peptides, Zhang Ling-Yu, Miao Jian-Yin, Cao Yu, Dai Wei-Jie, Liu Guo, Li Zhen-Wei, Cao Yong
Food and Machinery
Objective:This study aimed to develop new rice bran products.Methods:The ACE inhibition rate was used as an indicator, and the rice bran protein was optimized by single factor and response surface experiments. The optimal enzyme hydrolysate peptides were separated by ultrafiltration, activity evaluation and amino acid composition analysis were performed.Results:The optimal process conditions were as follows: pH 7.2, mass substrate concentration 8.2 g/100 mL, enzymolysis at 46 ℃ for 3 h, and enzyme addition 0.3 g/100 g rice bran protein. Under the control of these conditions, the ACE inhibition rate of the enzymatic hydrolysate was (73.15±0.64)%, …
Insights Into The Speciation Process From Genomic And Phenotypic Analysis Of An Avian Hybrid Zone In Amazonia, Glaucia Christina Del-Rio
Insights Into The Speciation Process From Genomic And Phenotypic Analysis Of An Avian Hybrid Zone In Amazonia, Glaucia Christina Del-Rio
LSU Doctoral Dissertations
Understanding the outcome of secondary contact is essential to shed light on the mechanisms governing species formation and maintenance. In Amazonia, closely related bird taxa with limited dispersal abilities are often separated by rivers, which presumably act as dispersal barriers. However, at the headwaters, rivers cease to be dispersal barriers, and this generates opportunities for secondary contact. In my dissertation, I studied genomic mechanisms associated with phenotypic differences, mitochondrial DNA structure, and putative reproductive barriers between two hybridizing Amazonian bird species in the genus Rhegmatorhina, a group of antbirds that find their arthropod prey exclusively by following army-ant swarms. …
Tp53 Copy Number And Protein Expression Inform Mutation Status Across Risk Categories In Acute Myeloid Leukemia, Mehrnoosh Tashakori, Tapan Kadia, Sanam Loghavi, Naval Daver, Rashmi Kanagal-Shamanna, Dawen Sui, Farnoosh Khodakarami, Zhenya Tang, Mark Routbort, Carol A Bivins, Elias J Jabbour, L Jeffrey Medeiros, Kapil Bhalla, Hagop M Kantarjian, Farhad Ravandi, Joseph D Khoury
Tp53 Copy Number And Protein Expression Inform Mutation Status Across Risk Categories In Acute Myeloid Leukemia, Mehrnoosh Tashakori, Tapan Kadia, Sanam Loghavi, Naval Daver, Rashmi Kanagal-Shamanna, Dawen Sui, Farnoosh Khodakarami, Zhenya Tang, Mark Routbort, Carol A Bivins, Elias J Jabbour, L Jeffrey Medeiros, Kapil Bhalla, Hagop M Kantarjian, Farhad Ravandi, Joseph D Khoury
Faculty, Staff and Student Publications
Mutant TP53 is an adverse risk factor in acute myeloid leukemia (AML), but large-scale integrated genomic-proteomic analyses of TP53 alterations in patients with AML remain limited. We analyzed TP53 mutational status, copy number (CN), and protein expression data in AML (N = 528) and provide a compilation of mutation sites and types across disease subgroups among treated and untreated patients. Our analysis shows differential hotspots in subsets of AML and uncovers novel pathogenic variants involving TP53 splice sites. In addition, we identified TP53 CN loss in 70.2% of TP53-mutated AML cases, which have more deleterious TP53 mutations, as well as …
Dissecting The Treatment-Naive Ecosystem Of Human Melanoma Brain Metastasis, Jana Biermann, Johannes C Melms, Amit Dipak Amin, Yiping Wang, Lindsay A Caprio, Somnath Tagore, Miguel A Ibarra-Arellano, Massimo Andreatta, Benjamin T Fullerton, Kristjan H Gretarsson, Varun Sahu, Vaibhav S Mangipudy, Trang T T Nguyen, Ajay Nair, Meri Rogava, Patricia Ho, Peter D Koch, Matei Banu, Nelson Humala, Aayushi Mahajan, Zachary H Walsh, Shivem B Shah, Daniel H Vaccaro, Blake Caldwell, Michael Mu, Florian Wünnemann, Margot Chazotte, Simon Berhe, Adrienne M Luoma, Joseph Driver, Matthew Ingham, Shaheer A Khan, Suthee Rapisuwon, Craig L Slingluff, Thomas Eigentler, Martin Röcken, Richard Carvajal, Michael B Atkins, Michael A Davies, Albert Agustinus, Samuel F Bakhoum, Elham Azizi, Markus Siegelin, Chao Lu, Santiago J Carmona, Hanina Hibshoosh, Antoni Ribas, Peter Canoll, Jeffrey N Bruce, Wenya Linda Bi, Praveen Agrawal, Denis Schapiro, Eva Hernando, Evan Z Macosko, Fei Chen, Gary K Schwartz, Benjamin Izar
Dissecting The Treatment-Naive Ecosystem Of Human Melanoma Brain Metastasis, Jana Biermann, Johannes C Melms, Amit Dipak Amin, Yiping Wang, Lindsay A Caprio, Somnath Tagore, Miguel A Ibarra-Arellano, Massimo Andreatta, Benjamin T Fullerton, Kristjan H Gretarsson, Varun Sahu, Vaibhav S Mangipudy, Trang T T Nguyen, Ajay Nair, Meri Rogava, Patricia Ho, Peter D Koch, Matei Banu, Nelson Humala, Aayushi Mahajan, Zachary H Walsh, Shivem B Shah, Daniel H Vaccaro, Blake Caldwell, Michael Mu, Florian Wünnemann, Margot Chazotte, Simon Berhe, Adrienne M Luoma, Joseph Driver, Matthew Ingham, Shaheer A Khan, Suthee Rapisuwon, Craig L Slingluff, Thomas Eigentler, Martin Röcken, Richard Carvajal, Michael B Atkins, Michael A Davies, Albert Agustinus, Samuel F Bakhoum, Elham Azizi, Markus Siegelin, Chao Lu, Santiago J Carmona, Hanina Hibshoosh, Antoni Ribas, Peter Canoll, Jeffrey N Bruce, Wenya Linda Bi, Praveen Agrawal, Denis Schapiro, Eva Hernando, Evan Z Macosko, Fei Chen, Gary K Schwartz, Benjamin Izar
Faculty, Staff and Student Publications
Melanoma brain metastasis (MBM) frequently occurs in patients with advanced melanoma; yet, our understanding of the underlying salient biology is rudimentary. Here, we performed single-cell/nucleus RNA-seq in 22 treatment-naive MBMs and 10 extracranial melanoma metastases (ECMs) and matched spatial single-cell transcriptomics and T cell receptor (TCR)-seq. Cancer cells from MBM were more chromosomally unstable, adopted a neuronal-like cell state, and enriched for spatially variably expressed metabolic pathways. Key observations were validated in independent patient cohorts, patient-derived MBM/ECM xenograft models, RNA/ATAC-seq, proteomics, and multiplexed imaging. Integrated spatial analyses revealed distinct geography of putative cancer immune evasion and evidence for more abundant …
Lncrna-Associated Genetic Etiologies Are Shared Between Type 2 Diabetes And Cancers In The Uae Population, Roberta Giordo, Rida Gulsha, Sarah Kalla, George A Calin, Leonard Lipovich
Lncrna-Associated Genetic Etiologies Are Shared Between Type 2 Diabetes And Cancers In The Uae Population, Roberta Giordo, Rida Gulsha, Sarah Kalla, George A Calin, Leonard Lipovich
Faculty, Staff and Student Publications
Numerous epidemiological studies place patients with T2D at a higher risk for cancer. Many risk factors, such as obesity, ageing, poor diet and low physical activity, are shared between T2D and cancer; however, the biological mechanisms linking the two diseases remain largely unknown. The advent of genome wide association studies (GWAS) revealed large numbers of genetic variants associated with both T2D and cancer. Most significant disease-associated variants reside in non-coding regions of the genome. Several studies show that single nucleotide polymorphisms (SNPs) at or near long non-coding RNA (lncRNA) genes may impact the susceptibility to T2D and cancer. Therefore, the …
Khsrp Loss Increases Neuronal Growth And Synaptic Transmission And Alters Memory Consolidation Through Rna Stabilization, Sarah L. Olguin, Priyanka Patel, Courtney N. Buchanan, Michela Dell'orco, Amy S. Gardiner, Robert Cole, Lauren S. Vaughn, Anitha Sundararajan, Joann Mudge, Andrea M. Allen, Pavel Ortinski, Jonathan L. Brigman, Jeffery L. Twiss, Nora L. Perrone-Bizzozero
Khsrp Loss Increases Neuronal Growth And Synaptic Transmission And Alters Memory Consolidation Through Rna Stabilization, Sarah L. Olguin, Priyanka Patel, Courtney N. Buchanan, Michela Dell'orco, Amy S. Gardiner, Robert Cole, Lauren S. Vaughn, Anitha Sundararajan, Joann Mudge, Andrea M. Allen, Pavel Ortinski, Jonathan L. Brigman, Jeffery L. Twiss, Nora L. Perrone-Bizzozero
Faculty Publications
KH-type splicing regulatory protein (KHSRP) regulates levels of several neuronal mRNAs linked to nervous system development and function.
The KH-type splicing regulatory protein (KHSRP) is an RNA-binding protein linked to decay of mRNAs with AU-rich elements. KHSRP was previously shown to destabilize Gap43 mRNA and decrease neurite growth in cultured embryonic neurons. Here, we have tested functions of KHSRP in vivo. We find upregulation of 1460 mRNAs in neocortex of adult Khsrp(-/-) mice, of which 527 bind to KHSRP with high specificity. These KHSRP targets are involved in pathways for neuronal morphology, axon guidance, neurotransmission and long-term memory. Khsrp(-/-) mice …
Bridging The Gap: Using College Athlete Support Services As Justification For Human Development In A Commercialized Sport Management, Sayvon Jl Foster, Calvin Nite
Bridging The Gap: Using College Athlete Support Services As Justification For Human Development In A Commercialized Sport Management, Sayvon Jl Foster, Calvin Nite
International Journal of Exercise Science
International Journal of Exercise Science 15(6): 934-947, 2022. This study investigates the presence of competing educational foundations within college athlete support service units across the 65 ‘Power Five’ conferences to call for more human development elements within sport management education and training. To determine the orientation of professionals within these units, educational foundation is used as the measure given the role education holds in establishing and communicating norms, values, and rules of practice for professionals within the discipline. Information was gathered through staff biographies and triangulated through secondary sources (university archives and social media accounts – LinkedIn and Twitter). Of …
Gender Barriers To Climate Change Adaptation Practices In Semi-Deciduous Forest Zone Of Ghana, Evans Amoako Amoah, Lawrence Damnyag, Frank Baffour-Ata, Dickson Boateng
Gender Barriers To Climate Change Adaptation Practices In Semi-Deciduous Forest Zone Of Ghana, Evans Amoako Amoah, Lawrence Damnyag, Frank Baffour-Ata, Dickson Boateng
Journal of Environmental Sustainability
This study investigated the gender barriers to climate change adaptation practices in the semi-deciduous forest zone of Ghana. A mixed methods approach including household surveys with 210 farmers and 14 focus group discussions was employed in seven selected communities in the Ejisu-Juaben Municipality of the Ashanti Region. The following research questions were answered by the study: (i) What are the climate change adaptation practices implemented by male and female farmers in selected communities of the Ejisu-Juaben Municipality to reduce climate risks? and; (ii) What are the barriers obstructing male and female farmers in implementing climate change adaptation practices in the …