Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Plant Sciences (42661)
- Medicine and Health Sciences (40642)
- Physical Sciences and Mathematics (39385)
- Biology (39146)
- Animal Sciences (36498)
-
- Agriculture (33744)
- Social and Behavioral Sciences (22994)
- Ecology and Evolutionary Biology (19750)
- Agronomy and Crop Sciences (16448)
- Earth Sciences (14808)
- Agricultural Science (14778)
- Plant Biology (13590)
- Medical Specialties (13393)
- Biochemistry, Biophysics, and Structural Biology (13223)
- Education (12536)
- Food Science (12464)
- Environmental Sciences (12105)
- Soil Science (12038)
- Medical Sciences (11768)
- Plant Pathology (11635)
- Forest Sciences (11517)
- Entomology (11473)
- Weed Science (11285)
- Botany (10776)
- Bioinformatics (10627)
- Zoology (10513)
- Kinesiology (10120)
- Arts and Humanities (9931)
- Genetics and Genomics (9421)
- Institution
-
- University of Nebraska - Lincoln (32965)
- Utah State University (16207)
- University of Kentucky (15585)
- TÜBİTAK (10915)
- The Texas Medical Center Library (8967)
-
- Department of Primary Industries and Regional Development, Western Australia (6321)
- University of Arkansas, Fayetteville (5658)
- Changsha University of Science and Technology (4816)
- Eastern Illinois University (4790)
- Brigham Young University (4342)
- South Dakota State University (4221)
- Western Kentucky University (4178)
- Old Dominion University (3350)
- Colby College (3264)
- Louisiana State University (2496)
- City University of New York (CUNY) (2468)
- Chulalongkorn University (2361)
- University of South Florida (2279)
- Nova Southeastern University (2231)
- California Polytechnic State University, San Luis Obispo (2152)
- Henry Ford Health (2151)
- Eastern Washington University (2054)
- Wright State University (1988)
- Virginia Commonwealth University (1904)
- University of Texas Rio Grande Valley (1830)
- WellBeing International (1823)
- The University of Southern Mississippi (1781)
- University of Nevada, Las Vegas (1769)
- Morehead State University (1759)
- University of South Carolina (1753)
- Keyword
-
- Humans (6379)
- Western Australia (3857)
- Agricultural newspapers (3000)
- American newspapers (3000)
- Central Maine (3000)
-
- Maine history (3000)
- Popular literature (3000)
- Animals (2817)
- 19th century newspapers (2670)
- Female (2509)
- Agriculture (2378)
- Male (2056)
- Mice (1852)
- National Smokejumper Association (1832)
- Smokejumpers -- United States (1828)
- Smokejumping (1825)
- Wildfire fighters (1825)
- Obituaries (1680)
- Biology (1540)
- Climate change (1414)
- Adult (1189)
- Ecology (1177)
- Nutrition (1152)
- Turkey (1135)
- Middle Aged (1120)
- Conservation (1096)
- Cancer (1048)
- Taxonomy (1039)
- Aged (1024)
- Biodiversity (1016)
- Publication Year
-
- 2026 (6790)
- 2025 (12490)
- 2024 (13256)
- 2023 (13873)
- 2022 (11692)
-
- 2021 (13347)
- 2020 (13409)
- 2019 (10619)
- 2018 (12524)
- 2017 (11217)
- 2016 (10289)
- 2015 (8769)
- 2014 (7604)
- 2013 (7708)
- 2012 (6459)
- 2011 (5494)
- 2010 (5158)
- 2009 (4546)
- 2008 (3983)
- 2007 (3588)
- 2006 (3140)
- 2005 (3238)
- 2004 (2672)
- 2003 (2546)
- 2002 (2962)
- 2001 (2467)
- 2000 (2412)
- 1999 (2285)
- 1998 (1948)
- 1996 (1673)
- Publication
-
- IGC Proceedings (1977-2023) (9261)
- Faculty, Staff and Student Publications (7587)
- Theses and Dissertations (5012)
- Food and Machinery (4816)
- Specimens by Name (3361)
-
- Turkish Journal of Veterinary & Animal Sciences (3215)
- Electronic Theses and Dissertations (3160)
- All Graduate Theses and Dissertations, Spring 1920 to Summer 2023 (2875)
- Faculty Publications (2626)
- Turkish Journal of Agriculture and Forestry (2171)
- The Waterville Mail (Waterville, Maine) (2161)
- Henry Ford Hospital Medical Journal (2151)
- Turkish Journal of Zoology (2109)
- University of Nebraska-Lincoln Extension: Historical Materials (2063)
- Journal of the Department of Agriculture, Western Australia, Series 4 (1916)
- All Current Publications (1886)
- Biology Faculty Publications (1771)
- Graduate Theses and Dissertations (1741)
- Turkish Journal of Botany (1739)
- Department of Agronomy and Horticulture: Faculty Publications (1713)
- Turkish Journal of Biology (1681)
- Smokejumper Obituaries (1679)
- The Great Lakes Entomologist (1578)
- Biological Sciences Faculty Publications (1574)
- Master's Theses (1568)
- Masters Theses (1550)
- The Thai Journal of Pharmaceutical Sciences (1535)
- United States Department of Agriculture Wildlife Services: Staff Publications (1530)
- Nebraska Bird Review (1477)
- All Peer-Reviewed Publications (1443)
- Publication Type
Articles 46921 - 46950 of 255953
Full-Text Articles in Life Sciences
Using Patient Flow Analysis With Real-Time Patient Tracking To Optimize Radiation Oncology Consultation Visits, Shane Mesko, Julius Weng, Prajnan Das, Albert C Koong, Joseph M Herman, Ashley Kerr, John Frenzel, Katy E French, Wendi Martinez, Iris Recinos, Abdulaziz Alshaikh, Utpala Daftary, Amy C Moreno, Quynh-Nhu Nguyen
Using Patient Flow Analysis With Real-Time Patient Tracking To Optimize Radiation Oncology Consultation Visits, Shane Mesko, Julius Weng, Prajnan Das, Albert C Koong, Joseph M Herman, Ashley Kerr, John Frenzel, Katy E French, Wendi Martinez, Iris Recinos, Abdulaziz Alshaikh, Utpala Daftary, Amy C Moreno, Quynh-Nhu Nguyen
Faculty, Staff and Student Publications
PURPOSE: Clinical efficiency is a key component of the value-based care model and a driver of patient satisfaction. The purpose of this study was to identify and address inefficiencies at a high-volume radiation oncology clinic.
METHODS AND MATERIALS: Patient flow analysis (PFA) was used to create process maps and optimize the workflow of consultation visits in a gastrointestinal radiation oncology clinic at a large academic cancer center. Metrics such as cycle times, waiting times, and rooming times were assessed by using a real-time patient status function in the electronic medical record for 556 consults and compared between before vs after …
Egfr-Phosphorylated Gdh1 Harmonizes With Rsk2 To Drive Creb Activation And Tumor Metastasis In Egfr-Activated Lung Cancer, Jihoon Kang, Jaemoo Chun, Jung Seok Hwang, Chaoyun Pan, Jie Li, Isabelle Young, Yibin Kang, Don L Gibbons, Gabriel Sica, Haian Fu, Suresh S Ramalingam, Lingtao Jin, Sumin Kang
Egfr-Phosphorylated Gdh1 Harmonizes With Rsk2 To Drive Creb Activation And Tumor Metastasis In Egfr-Activated Lung Cancer, Jihoon Kang, Jaemoo Chun, Jung Seok Hwang, Chaoyun Pan, Jie Li, Isabelle Young, Yibin Kang, Don L Gibbons, Gabriel Sica, Haian Fu, Suresh S Ramalingam, Lingtao Jin, Sumin Kang
Faculty, Staff and Student Publications
The cancer metastasis process involves dysregulated oncogenic kinase signaling, but how this orchestrates metabolic networks and signal cascades to promote metastasis is largely unclear. Here we report that inhibition of glutamate dehydrogenase 1 (GDH1) and ribosomal S6 kinase 2 (RSK2) synergistically attenuates cell invasion, anoikis resistance, and immune escape in lung cancer and more evidently in tumors harboring epidermal growth factor receptor (EGFR)-activating or EGFR inhibitor-resistant mutations. Mechanistically, GDH1 is activated by EGFR through phosphorylation at tyrosine 135 and, together with RSK2, enhances the cAMP response element-binding protein (CREB) activity via CaMKIV signaling, thereby promoting metastasis. Co-targeting RSK2 and GDH1 …
Histopathological Tumour Response Scoring In Resected Pancreatic Cancer Following Neoadjuvant Therapy: International Interobserver Study (Isgpp-1), Boris V Janssen, Stijn Van Roessel, Susan Van Dieren, Onno De Boer, Volkan Adsay, Lodewijk Brosens, Deyali Chatterjee, Angela Chou, Claudio Doglioni, Irene Esposito, Roger Feakins, Talia L Fuchs, Noriyoshi Fukushima, Anthony J Gill, Seung-Mo Hong, Ralph H Hruban, Jeffrey Kaplan, Alyssa Krasinkas, Claudio Luchini, Chanjuan Shi, Aatur Singhi, Elizabeth Thompson, Marie-Louise F Velthuysen, Marc G Besselink, Joanne Verheij, Huamin Wang, Caroline Verbeke, Arantza Fariña
Histopathological Tumour Response Scoring In Resected Pancreatic Cancer Following Neoadjuvant Therapy: International Interobserver Study (Isgpp-1), Boris V Janssen, Stijn Van Roessel, Susan Van Dieren, Onno De Boer, Volkan Adsay, Lodewijk Brosens, Deyali Chatterjee, Angela Chou, Claudio Doglioni, Irene Esposito, Roger Feakins, Talia L Fuchs, Noriyoshi Fukushima, Anthony J Gill, Seung-Mo Hong, Ralph H Hruban, Jeffrey Kaplan, Alyssa Krasinkas, Claudio Luchini, Chanjuan Shi, Aatur Singhi, Elizabeth Thompson, Marie-Louise F Velthuysen, Marc G Besselink, Joanne Verheij, Huamin Wang, Caroline Verbeke, Arantza Fariña
Faculty, Staff and Student Publications
Background: Most tumour response scoring systems for resected pancreatic cancer after neoadjuvant therapy score tumour regression. However, whether treatment-induced changes, including tumour regression, can be identified reliably on haematoxylin and eosin-stained slides remains unclear. Moreover, no large study of the interobserver agreement of current tumour response scoring systems for pancreatic cancer exists. This study aimed to investigate whether gastrointestinal/pancreatic pathologists can reliably identify treatment effect on tumour by histology, and to determine the interobserver agreement for current tumour response scoring systems.
Methods: Overall, 23 gastrointestinal/pancreatic pathologists reviewed digital haematoxylin and eosin-stained slides of pancreatic cancer or treated tumour bed. The …
Defining Cellular Population Dynamics At Single-Cell Resolution During Prostate Cancer Progression, Alexandre A Germanos, Sonali Arora, Ye Zheng, Erica T Goddard, Ilsa M Coleman, Scott Wilkinson, Nicholas J Brady, Robert A Amezquita, Michael Zager, Annalysa Long, Yu Chi Yang, Jason H Bielas, Raphael Gottardo, David S Rickman, Franklin W Huang, Cyrus M Ghajar, Peter S Nelson, Adam G Sowalsky, Manu Setty, Andrew C Hsieh
Defining Cellular Population Dynamics At Single-Cell Resolution During Prostate Cancer Progression, Alexandre A Germanos, Sonali Arora, Ye Zheng, Erica T Goddard, Ilsa M Coleman, Scott Wilkinson, Nicholas J Brady, Robert A Amezquita, Michael Zager, Annalysa Long, Yu Chi Yang, Jason H Bielas, Raphael Gottardo, David S Rickman, Franklin W Huang, Cyrus M Ghajar, Peter S Nelson, Adam G Sowalsky, Manu Setty, Andrew C Hsieh
Faculty, Staff and Student Publications
Advanced prostate malignancies are a leading cause of cancer-related deaths in men, in large part due to our incomplete understanding of cellular drivers of disease progression. We investigate prostate cancer cell dynamics at single-cell resolution from disease onset to the development of androgen independence in an in vivo murine model. We observe an expansion of a castration-resistant intermediate luminal cell type that correlates with treatment resistance and poor prognosis in human patients. Moreover, transformed epithelial cells and associated fibroblasts create a microenvironment conducive to pro-tumorigenic immune infiltration, which is partially androgen responsive. Androgen-independent prostate cancer leads to significant diversification of …
Comparison Of Supine And Vertical Bioimpedance Measurements In Young Adults, Jeremy B. Ducharme, Chloe Clark, Jonathan M. Houck, Holly Hall, Avadney Gerard-Osbourne, Ann Gibson
Comparison Of Supine And Vertical Bioimpedance Measurements In Young Adults, Jeremy B. Ducharme, Chloe Clark, Jonathan M. Houck, Holly Hall, Avadney Gerard-Osbourne, Ann Gibson
Topics in Exercise Science and Kinesiology
Topics in Exercise Science and Kinesiology Volume 3: Issue 1, Article 11, 2022. Bioelectrical impedance analysis (BIA) methods estimate health parameters such as phase angle (PhA) and body fat percentage (%BF) from various positional and electrode configurations. PhA and %BF are known biological markers of cellular and physical health, respectively, and can be used to predict various health-related conditions and therefore require accurate assessment. The purpose of this study was to evaluate the effect of body position during BIA by investigating the difference and agreement between PhA and %BF using RJL (supine) and InBody (vertical) analyzers. Thirty-eight young adults (23.4 …
Influence Of Environmental Factors On Surface Activity Of Paruroctonus Marksi (Scorpiones: Vaejovidae) In The Mojave Desert, Zia Nisani, Destiny Frederick, Alejandro Garcia-Plascencia, Daian Lopez, Robert Miller, Linhsan Trinh-Nguyen
Influence Of Environmental Factors On Surface Activity Of Paruroctonus Marksi (Scorpiones: Vaejovidae) In The Mojave Desert, Zia Nisani, Destiny Frederick, Alejandro Garcia-Plascencia, Daian Lopez, Robert Miller, Linhsan Trinh-Nguyen
Euscorpius
Many environmental factors may influence the activity pattern of scorpions in arid ecosystems. We investigated the seasonal variations of Paruroctonus marksi scorpion activity in the Mojave Desert (California, USA). Black light surveys were carried out within two 100 ×100 m plots from August 2017 to September 2018. The majority (85%) of scorpions were found in open areas compared with being in vegetation. The presence of P. marksi was positively correlated with both water vapor pressure and soil temperature, while moon illumination had no significant effect on P. marksi foraging behavior. Scorpions might be using humidity as an indicator of prey …
Examples Of Insect Mouthparts, Bethia H. King
Examples Of Insect Mouthparts, Bethia H. King
Books, Book Chapters, & Supplemental Materials
Renderings of mouthparts for honey bees, house flies, grasshoppers, lepidopterans, mosquitoes, and hemipterans.
Developing And Utilizing Novel Biofluid N-Glycan Profiling Methods For The Classification Of Suspicious Mammogram Findings, Calvin Blaschke
Developing And Utilizing Novel Biofluid N-Glycan Profiling Methods For The Classification Of Suspicious Mammogram Findings, Calvin Blaschke
MUSC Theses and Dissertations
Biofluids are a great source of biomarkers because they reflect the immune and metabolic status of cells throughout the body and can be collected non-invasively. Changes in the levels and compositions of N-glycans released from serum and plasma glycoproteins have been assessed in many diseases across many large clinical sample cohorts. Assays used for N-glycan profiling in these fluids currently require multiple lengthy processing steps, thus diminishing their potential for use as standard clinical diagnostic assays. In response to this need for rapid, simple, and high-throughput biofluid analysis, a novel slide-based biofluid profiling platform was developed for the detection of …
Contextualising The Pillars Of Household Food Security: Evidence From Iringa District, Tanzania, Tiemo Romward Haule
Contextualising The Pillars Of Household Food Security: Evidence From Iringa District, Tanzania, Tiemo Romward Haule
Journal of Humanities and Social Sciences
This paper contextualises the pillars of food security based on the perceptions of local communities in Iringa district, Tanzania. The pillars are food availability, food accessibility, food affordability, food adequacy, food acceptability and food stability. The study involved 376 participants. Structured interviews, field observation, focused group discussions, in depth interviews and documentary review were the methods used for data collection. Findings reveal that many households (76.2%) in Iringa were facing food shortage. The findings show that food insecurity in the district was exacerbated by the lack of steadiness in the six pillars of household food security. Given its semi-arid climatic …
Does Predation Environment Affect Repeated Responses To Predation Cuesâ In The Fishâ Brachyrhaphis Rhabdophora?, Madeleine S. Nate
Does Predation Environment Affect Repeated Responses To Predation Cuesâ In The Fishâ Brachyrhaphis Rhabdophora?, Madeleine S. Nate
Theses and Dissertations
Individual organisms face trade-offs when dealing with predation—more time spent avoiding predators often results in less time allocated to energy acquisition and reproductive-related activities. Individuals that optimize this trade-off and respond appropriately to current risk levels in their environment should be at an advantage. What is less clear is whether this tradeoff changes when individuals are repeatedly exposed to a predation threat. There may be advantages to responding consistently to every signal of threat, but it might also be advantageous to modulate individual behavior. Moreover, it is unclear how evolutionary history of a population might affect such individual responses. Our …
Bis-Indolyl Compounds And The Induction Of Apoptosis In T98g Glioblastoma Multiforme Cells, Margot C. Brown
Bis-Indolyl Compounds And The Induction Of Apoptosis In T98g Glioblastoma Multiforme Cells, Margot C. Brown
Seton Hall University Dissertations and Theses (ETDs)
1,1-bis(3’idolyl)-1(aryl)methane compounds (BIM compounds) have been shown to have anti-cancer properties in colon cancer, bladder cancer, and leukemia cells. The purpose of this work was to determine if BIM compounds could be an effective treatment of glioblastoma multiforme. Sulforhodamine B (SRB) assays showed that 20µM of the BIM compounds could inhibit cellular proliferation of the T98G glioblastoma multiforme cell line over 72 hours. Then immunoblotting was used to analyze the molecular pathway induced by BIM compounds. An increase in the expression of both BAX and cleaved caspase 3 suggest BIM compounds activate programmed cell death, or apoptosis in glioblastoma cells. …
Quantifying Shape Variation In An Antisymmetrical Trait In Xenophallus Umbratilis, Mary-Elise Johnson Nielsen
Quantifying Shape Variation In An Antisymmetrical Trait In Xenophallus Umbratilis, Mary-Elise Johnson Nielsen
Theses and Dissertations
Antisymmetry is a striking, yet puzzling form of biological asymmetry. The livebearing fish Xenophallus umbratilis exhibits antisymmetry in the male intromittent organ and provides a system that is well-suited for studying the nature of variation in antisymmetrical traits. Using geometric morphometrics, I test the hypothesis that because the gonopodium is critical to fitness there will not be significant differences in gonopodium shape between the two gonopodial morphs in this species. My results are consistent with this prediction, though I found that gonopodium shape did differ with gonopodium size.
Issues In Melanoma Detection: Semisupervised Deep Learning Algorithm Development Via A Combination Of Human And Artificial Intelligence, Mena Kozman, Carly Stender, Luca Giancardo, Cui Tao
Issues In Melanoma Detection: Semisupervised Deep Learning Algorithm Development Via A Combination Of Human And Artificial Intelligence, Mena Kozman, Carly Stender, Luca Giancardo, Cui Tao
Faculty, Staff and Student Publications
BACKGROUND: Automatic skin lesion recognition has shown to be effective in increasing access to reliable dermatology evaluation; however, most existing algorithms rely solely on images. Many diagnostic rules, including the 3-point checklist, are not considered by artificial intelligence algorithms, which comprise human knowledge and reflect the diagnosis process of human experts.
OBJECTIVE: In this paper, we aimed to develop a semisupervised model that can not only integrate the dermoscopic features and scoring rule from the 3-point checklist but also automate the feature-annotation process.
METHODS: We first trained the semisupervised model on a small, annotated data set with disease and dermoscopic …
Social Behavior And Youth Psychopathology During The Covid-19 Pandemic: A Longitudinal Study, Alexandra M. Rodman, Maya L. Rosen, Steven W. Kasparek, Makeda Mayes, Liliana Lengua, Andrew N. Meltzoff, Katie A. Mclaughlin
Social Behavior And Youth Psychopathology During The Covid-19 Pandemic: A Longitudinal Study, Alexandra M. Rodman, Maya L. Rosen, Steven W. Kasparek, Makeda Mayes, Liliana Lengua, Andrew N. Meltzoff, Katie A. Mclaughlin
Neuroscience: Faculty Publications
The early stages of the COVID-19 pandemic and associated stay-at-home orders resulted in a stark reduction in daily social interactions for children and adolescents. Given that peer relationships are especially important during this developmental stage, it is crucial to understand the impact of the COVID-19 pandemic on social behavior and risk for psychopathology in children and adolescents. In a longitudinal sample (N=224) of children (7-10y) and adolescents (13-15y) assessed at three strategic time points (before the pandemic, during the initial stay-at-home order period, and six months later after the initial stay-at-home order period was lifted), we examine whether certain social …
Enhanced Structural Control Of Soft-Templated Mesoporous Inorganic Thin Films By Inert Processing Conditions, Maximilliano Jesus Jara Fornerod, Alberto Alvarez-Fernandez, Eric R. Williams, Miximillian W.A. Skoda, Beatriz Prieto-Simon, Nicolas H. Voelcker, Morgan Stefik, Marc-Oliver Coppens, Stefan Guldin
Enhanced Structural Control Of Soft-Templated Mesoporous Inorganic Thin Films By Inert Processing Conditions, Maximilliano Jesus Jara Fornerod, Alberto Alvarez-Fernandez, Eric R. Williams, Miximillian W.A. Skoda, Beatriz Prieto-Simon, Nicolas H. Voelcker, Morgan Stefik, Marc-Oliver Coppens, Stefan Guldin
Faculty Publications
Mesoporous thin films are widely used for applications in need of high surface area and efficient mass and charge transport properties. A well-established fabrication process involves the supramolecular assembly of organic molecules (e.g., block copolymers and surfactants) with inorganic materials obtained by sol-gel chemistry. Typically, subsequent calcination in air removes the organic template and reveals the porous inorganic network. A significant challenge for such coatings is the anisotropic shrinkage due to the volume contraction related to solvent evaporation, inorganic condensation, and template removal, affecting the final porosity as well as pore shape, size, arrangement, and accessibility. Here, we show that …
Development Of Functional Markers For Resistance To Smut And Identification Of Genes Differentially Expressed In Response To Brown Rust In Sugarcane, Jose David Cortes
Development Of Functional Markers For Resistance To Smut And Identification Of Genes Differentially Expressed In Response To Brown Rust In Sugarcane, Jose David Cortes
LSU Doctoral Dissertations
Smut, caused by Sporisorium scitamineum and brown rust, caused by Puccinia melanocephala, are two of the most important diseases that affect sugarcane production in Louisiana and worldwide. Smut continues to cause losses in the breeding program in Louisiana. Therefore, a QTL analysis was conducted to identify molecular markers associated with resistance in F1 progeny (162) of a biparental cross between susceptible cultivar L 99-233 and resistant HoCP 96-540. Using 1,574 single-dose SNP markers, a total of 253 linkage groups (LG) were obtained with a genome coverage of 24,580.15 cM. Six QTLs were localized on five LGs. The highest …
Gabapentin Disrupts Binding Of Perlecan To The Α 2Δ1 Voltage Sensitive Calcium Channel Subunit And Impairs Skeletal Mechanosensation, Perla C Reyes Fernandez, Christian S Wright, Adrianna N Masterson, Xin Yi, Tristen V Tellman, Katie Rust, Kenneth E White, Karl J Lewis, Uma Sankar, Julia M Hum, Gregory Bix, Danielle Wu, Alexander G Robling, Rajesh Sardar, Mary C Farach-Carson, William R Thompson
Gabapentin Disrupts Binding Of Perlecan To The Α 2Δ1 Voltage Sensitive Calcium Channel Subunit And Impairs Skeletal Mechanosensation, Perla C Reyes Fernandez, Christian S Wright, Adrianna N Masterson, Xin Yi, Tristen V Tellman, Katie Rust, Kenneth E White, Karl J Lewis, Uma Sankar, Julia M Hum, Gregory Bix, Danielle Wu, Alexander G Robling, Rajesh Sardar, Mary C Farach-Carson, William R Thompson
Faculty, Staff and Student Publications
Our understanding of how osteocytes, the principal mechanosensors within bone, sense and perceive force remains unclear. Previous work identified "tethering elements" (TEs) spanning the pericellular space of osteocytes and transmitting mechanical information into biochemical signals. While we identified the heparan sulfate proteoglycan perlecan (PLN) as a component of these TEs, PLN must attach to the cell surface to induce biochemical responses. As voltage-sensitive calcium channels (VSCCs) are critical for bone mechanotransduction, we hypothesized that PLN binds the extracellular α2δ1 subunit of VSCCs to couple the bone matrix to the osteocyte membrane. Here, we showed co-localization of PLN and α2δ1 along …
Mapping Single-Cell Transcriptomes In The Intra-Tumoral And Associated Territories Of Kidney Cancer, Ruoyan Li, John R Ferdinand, Kevin W Loudon, Georgina S Bowyer, Sean Laidlaw, Lira Mamanova, Liam Bolt, Eirini S Fasouli, Andrew R J Lawson, Matthew D Young, Yvette Hooks, Thomas R W Oliver, Timothy M Butler, James N Armitage, Tev Aho, Antony C P Riddick, Vincent Gnanapragasam, Sarah J Welsh, Kerstin B Meyer, Anne Y Warren, Maxine G B Tran, Grant D Stewart, Isidro Cortés-Ciriano, Sam Behjati, Menna R Clatworthy, Peter J Campbell, Sarah A Teichmann, Thomas J Mitchell
Mapping Single-Cell Transcriptomes In The Intra-Tumoral And Associated Territories Of Kidney Cancer, Ruoyan Li, John R Ferdinand, Kevin W Loudon, Georgina S Bowyer, Sean Laidlaw, Lira Mamanova, Liam Bolt, Eirini S Fasouli, Andrew R J Lawson, Matthew D Young, Yvette Hooks, Thomas R W Oliver, Timothy M Butler, James N Armitage, Tev Aho, Antony C P Riddick, Vincent Gnanapragasam, Sarah J Welsh, Kerstin B Meyer, Anne Y Warren, Maxine G B Tran, Grant D Stewart, Isidro Cortés-Ciriano, Sam Behjati, Menna R Clatworthy, Peter J Campbell, Sarah A Teichmann, Thomas J Mitchell
Faculty, Staff and Student Publications
Tumor behavior is intricately dependent on the oncogenic properties of cancer cells and their multi-cellular interactions. To understand these dependencies within the wider microenvironment, we studied over 270,000 single-cell transcriptomes and 100 microdissected whole exomes from 12 patients with kidney tumors, prior to validation using spatial transcriptomics. Tissues were sampled from multiple regions of the tumor core, the tumor-normal interface, normal surrounding tissues, and peripheral blood. We find that the tissue-type location of CD8+ T cell clonotypes largely defines their exhaustion state with intra-tumoral spatial heterogeneity that is not well explained by somatic heterogeneity. De novo mutation calling from single-cell …
Experiences Of Parents With Opioid Use Disorder During Their Attempts To Seek Treatment: A Qualitative Analysis
Faculty, Staff and Student Publications
In the U.S., 12.3% of children live with at least one parent who has a substance use disorder. Prior research has shown that men are more likely to seek treatment than women and that the barriers are different; however, there is limited research focusing specifically on opioid use disorder (OUD). We sought to understand the barriers and motivators for parents with OUD. We conducted a qualitative study by interviewing parents with OUD who were part of an outpatient treatment program. Interviews followed a semi-structured format with questions on access to and motivation for treatment. The interviews were recorded and transcribed …
Advancing Access To Healthcare Through Telehealth: A Brownsville Community Assessment
Advancing Access To Healthcare Through Telehealth: A Brownsville Community Assessment
Faculty, Staff and Student Publications
(1) Background: This paper focuses on the development of a community assessment for telehealth using an interprofessional lens, which sits at the intersection of public health and urban planning using multistakeholder input. The paper analyzes the process of designing and implementing a telemedicine plan for the City of Brownsville and its surrounding metros. (2) Methods: We employed an interprofessional approach to CBPR which assumed all stakeholders as equal partners alongside the researchers to uncover the most relevant and useful knowledge to inform the development of telehealth community assessment. (3) Results: Key findings include that: physicians do not have the technology, …
Aspectos De La Investigación Del Cacao En Municipios De La Zona Del Tequendama, Jenny Paola Moreno Lopez, Laguandio Del Cristo Banda Sánchez, Arlette Ivone Gil Clavijo, Diego Orlando Méndez Pineda, Fabián Giovanny Marquez Niño
Aspectos De La Investigación Del Cacao En Municipios De La Zona Del Tequendama, Jenny Paola Moreno Lopez, Laguandio Del Cristo Banda Sánchez, Arlette Ivone Gil Clavijo, Diego Orlando Méndez Pineda, Fabián Giovanny Marquez Niño
Ciencias Agropecuarias
El mejoramiento del manejo fitosanitario en producciones de cacao (Theobrorna cacao L) involucra el uso de alternativas amigables como los productos a base de plantas con actividad antimicrobiana tal es el caso del género Piper. Esta investigación buscó cuantificar las enfermedades presentes en plantaciones de cacao en municipios de la región del Tequendama Cundinamarca-Colombia y evaluar aspectos eco fisiológicos de Piper SP. Se trabajó en seis fincas de la Asociación de Cacaoteros del Bajo Tequendama en Viotá, Anapoima y Tocaima. Se evaluó la incidencia y severidad de las enfermedades y se generaron mapas de calor. Se tomaron muestras vegetales sintomáticas …
Indicadores De Sustentabilidad Vba Mesmis, Geovanny Andres Martinez Jimenez
Indicadores De Sustentabilidad Vba Mesmis, Geovanny Andres Martinez Jimenez
Ciencias Administrativas, Económicas y Contables
El presente libro se ha diseñado con el propósito de que el lector tenga una experiencia satisfactoria al momento de emplear los indicadores VBA MESMIS. Por tanto, el documento se estructura de manera minuciosa en dos apartados; el primero que trata acerca de los criterios de diagnóstico, en el que se plantea un ejemplo con información de tres unidades productivas, con el fin de i) desarrollar los indicadores correspondientes a los criterios; ii) conocer el nivel de desempeño de los indicadores; iii) realizar un análisis general y proponer recomendaciones para el fortalecimiento de la sustentabilidad de las unidades productivas; en …
A Deep Look Into Languages And Research, Martha Isabel Diaz Ramirez, Francy Elena Martinez Franco, Rafael Leonardo Cortes Lugo, Marcela Diaz Ramirez, Rosa Delia Acosta, Helva Luz Palacios, Norma Constanza Durán Narváez, Gloria Milena Castellanos Mendoza, Angela Andrea Ariza Higuera, Ana Milena Morales Sossa, Adriana Paola Bendek, Adriana Carolina Torres Escobar, Alejandro Fernandez Benavides, Maria Elena Garassini Chávez, Hugo Mauricio Aldana Zárate, Diana Marcela Fúneme Estupiñan, Janneth Mercedes Mora Yate, Jhonatan Vásquez Guarnizo, Finn Ale Álvarez Contreras, Paola Ximena Romero Molina
A Deep Look Into Languages And Research, Martha Isabel Diaz Ramirez, Francy Elena Martinez Franco, Rafael Leonardo Cortes Lugo, Marcela Diaz Ramirez, Rosa Delia Acosta, Helva Luz Palacios, Norma Constanza Durán Narváez, Gloria Milena Castellanos Mendoza, Angela Andrea Ariza Higuera, Ana Milena Morales Sossa, Adriana Paola Bendek, Adriana Carolina Torres Escobar, Alejandro Fernandez Benavides, Maria Elena Garassini Chávez, Hugo Mauricio Aldana Zárate, Diana Marcela Fúneme Estupiñan, Janneth Mercedes Mora Yate, Jhonatan Vásquez Guarnizo, Finn Ale Álvarez Contreras, Paola Ximena Romero Molina
Ciencias Sociales, Humanidades y Ciencias Políticas
RESUMEN: Investigue va más allá de las estadísticas y los números aislados. La investigación implica una indagación sistemática con una reflexión profunda para resolver problemas o enriquecer los conocimientos disponibles, en este caso las Humanidades incluyen una variedad ilimitada de ramas agrupadas en cinco áreas como son las artes, los idiomas, la literatura, la religión y la historia . Las humanidades ayudan a las comunidades a comprender el mundo en el que estamos inmersos y fomentan la formación de ciudadanos críticos. De hecho, las lenguas brindan herramientas para preservar la identidad y mejorar la calidad de vida en varias culturas …
Respons Komponen Hasil Dan Hasil Varietas Padi Berprotein Tinggi Terhadap Pemberian Dosis Pupuk Nitrogen, Agus Riyanto, Dyah Susanti, Totok Agung Dwi Haryanto
Respons Komponen Hasil Dan Hasil Varietas Padi Berprotein Tinggi Terhadap Pemberian Dosis Pupuk Nitrogen, Agus Riyanto, Dyah Susanti, Totok Agung Dwi Haryanto
Jurnal Kultivasi
Inpago Unsoed Protani dan Inpari Unsoed P20Tangguh adalah padi (Oryza sativa L.) daya hasil tinggi yang memiliki kandungan protein beras tinggi yang pertumbuhannya dipengaruhi oleh pemupukan nitrogen. Tujuan penelitian ini adalah mengetahui respons komponen hasil dan hasil padi protein tinggi terhadap pupuk nitrogen dan memperoleh dosis optimal pupuk nitrogen untuk varietas Inpago Unsoed Protani dan Inpari Unsoed P20Tangguh. Percobaan dirancang dengan RAK pola faktorial dwi faktor yang diulang tiga kali. Faktor pertama adalah dosis pupuk N yaitu: 0 kg N ha-1, 46 kg N ha-1, 92 kg N ha-1, dan 138 kg N ha-1. Faktor kedua adalah genotipe padi yaitu …
Potential Use Of Pgpr Based Biofertilizer For Improving The Nutrient Availability In Soil And Agronomic Efficiency Of Upland Rice, Rahma Tia Harahap, Diyan Herdiyantoro, Mieke Rochimi Setiawati, Isna Niar Rahmatul Azizah, Tualar Simarmata
Potential Use Of Pgpr Based Biofertilizer For Improving The Nutrient Availability In Soil And Agronomic Efficiency Of Upland Rice, Rahma Tia Harahap, Diyan Herdiyantoro, Mieke Rochimi Setiawati, Isna Niar Rahmatul Azizah, Tualar Simarmata
Jurnal Kultivasi
Present study aimed to perform literature review to investigate the current status and potential use of plant growth promoting rhizobacteria (PGPR) for enhancing the soil plant’s health, plant growth and productivity in sustainable ways. The Systematic Literature Review (SLR) methods was applied according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) on published scientific literature from 2012-2022. Results revealed that genus diversity of PGPR (Bacillus sp., Serratia sp., Streptomyces sp., Pseudomonas sp., and Burkholderia sp.) produce siderophore and phytohormones such as indole-3-acetic acid (IAA), gibberellin (GAs), auxin, and 1-aminocyclopropane-1-carboxylic acid (ACC) deaminase activity, organic acids, biocontrol agent that …
Microplastic Accumulation In The Digestive Tract Of Young-Of-Year Atlantic Sharpnose Sharks (Rhizoprionodon Terraenovae) In The Grand Strand, Sc, Andrew Curtis Sitlinger
Microplastic Accumulation In The Digestive Tract Of Young-Of-Year Atlantic Sharpnose Sharks (Rhizoprionodon Terraenovae) In The Grand Strand, Sc, Andrew Curtis Sitlinger
Electronic Theses and Dissertations
This study focused on the presence and accumulation of microplastic fibers in the digestive tract and livers of young-of-year Atlantic Sharpnose Sharks (Rhizopriondon terraenovae) from two sampling locations along the Grand Strand of South Carolina. R. terraenovae is a small, mesopredatory elasmobranch found abundantly along northwestern Atlantic Ocean coastlines. Thirty specimens of R. terraenovae were collected from May through August of 2020. Microplastics were found in all specimens. A total of 672 plastic particles were identified over the course of the study, with an average of 22.4 ± 10.5 (SD) plastics per specimen. The majority of the plastics were classified …
Fine-Scale Site Selection Of Strand-Feeding Common Bottlenose Dolphins (Tursiops Truncatus) And Their Prey, Deborah Kleinclaus
Fine-Scale Site Selection Of Strand-Feeding Common Bottlenose Dolphins (Tursiops Truncatus) And Their Prey, Deborah Kleinclaus
Electronic Theses and Dissertations
Strand-feeding is a unique, cooperative foraging strategy used by some common bottlenose dolphins (Tursiops truncatus) at low tide in South Carolina and Georgia salt marshes, where a group of dolphins charges schools of fish, thrusting them onto the bank with their bow wave and then capturing prey items onshore. Strand-feeding dolphins are estuarine residents and frequent predictable stranding sites, suggesting an intimate knowledge of the area. Dolphin behavior prior to stranding suggests they do not herd the fish before charging, but instead prey on fish already shoaling near the bank. The use of active acoustics from strand-feeders in order to …
Next-Generation Sequencing Shows Increasing Temperatures Affect Stream Fungal Communities, Regan Hodgson
Next-Generation Sequencing Shows Increasing Temperatures Affect Stream Fungal Communities, Regan Hodgson
Electronic Theses and Dissertations
Under climate change predictions, surface air temperature is expected to continue to rise and will likely affect functioning of stream ecosystems and microbial communities. Aquatic hyphomycetes are key fungal decomposers of plant litter in headwater streams controlling carbon, energy, and nutrient flows to higher trophic levels. This project addressed the effects of temperature on stream fungal communities in two recently conducted experiments (microcosm and streamside channel studies) using Illumina sequencing. The objectives were to determine (1) if temperature affects community structure of stream fungi based on relative abundances of ITS2 rDNA sequences, (2) if the effects of temperature on aquatic …
Abundance And Growth Of Juvenile Atlantic Sturgeon In The Edisto River, Sc, Molly Katherine Takacs
Abundance And Growth Of Juvenile Atlantic Sturgeon In The Edisto River, Sc, Molly Katherine Takacs
Electronic Theses and Dissertations
Information on abundance and body growth are important for understanding the status and health of populations, and this information can be used to guide and monitor conservation and recovery efforts for species of conservation concern. The Atlantic Sturgeon (Acipenser oxyrinchus oxyrinchus) is an anadromous fish native to the Atlantic coast of the United States and Canada. Due to overfishing and habitat degradation, population levels declined, and Atlantic Sturgeon were placed on the Endangered Species list in 2012. Although there is substantial research on adult Atlantic Sturgeon, knowledge about their early life history is lacking. The objective of this study were …
Extraction, Analysis, And Comparison Of Microplastics In Sc Marsh Substrates, Austin G. Sige
Extraction, Analysis, And Comparison Of Microplastics In Sc Marsh Substrates, Austin G. Sige
Electronic Theses and Dissertations
The global, rapid increase in plastic production is a widespread problem for coastal environments such as marshes that present favorable conditions for plastic retention. This study looked at the microplastic abundance within three previously unstudied South Carolina marshes located in Myrtle Beach, Murrells Inlet, and Waties Island. A comparison between the microplastic types and abundances between locations provided knowledge about the impacts of sediment composition (sand, silt, clay, and organic matter) on microplastic sequestration. This study also produced a novel microplastic extraction methodology for cohesive marsh sediment that used elutriation to effectively break apart aggregates prior to chemical digestion and …