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Full-Text Articles in Life Sciences

Naturally Derived Fibrous Scaffolds Containing Metabolic Factors For Bone Tissue Engineering, Apurva Limaye Dec 2022

Naturally Derived Fibrous Scaffolds Containing Metabolic Factors For Bone Tissue Engineering, Apurva Limaye

Dissertations

More than 500,000 bone grafting procedures are performed each year to treat bone defects, trauma, and non-unions. Current strategies, including autografts and allografts, face limitations that include donor site morbidity and poor integration, respectively. Treatments using the delivery of the growth factor, bone morphogenetic protein-2 (BMP2), result in ectopic bone formation and adverse effects at high doses. Tissue engineering strategies are utilized to combat these challenges. Natural biomaterials are commonly used as tissue engineering scaffolds due to their biocompatibility, biodegradability, and they can promote cellular function. However, animal-derived materials can have limitations in availability, lot to lot variability and potential …


Microplastics And Genetic Vectors Promoting The Dissemination Of Antimicrobial Resistance In Municipal Wastewater Treatment Processes, Ngoc Dung Pham Dec 2022

Microplastics And Genetic Vectors Promoting The Dissemination Of Antimicrobial Resistance In Municipal Wastewater Treatment Processes, Ngoc Dung Pham

Dissertations

The spread of antimicrobial resistance in the environment and especially its transfer into human pathogens have emerged as global issues. Activated sludge units at municipal wastewater treatment plants are "hotspots" converging a multitude of contaminants, including antibiotics, antibiotic-resistant bacteria (ARB), human pathogens, and microplastics. The prevalence of antibiotics can induce stress response of sludge microbial communities and promote the development of new resistance mechanisms and transmission venues, through which the dissemination of antibiotic resistance genes (ARGs) arises as mediated by mobile genetic elements (MGEs). In this doctoral dissertation, the impacts of microplastics and genetic vectors (i.e., MGEs and bacterial hosts) …


Urban Farming: Empowerment To Increase Economic, Education, And Nutritional Benefit For The Sub-Urban Community, Nasruddin Nasruddin, Yusuf Donner Dwiyantama, Banu Muhammad, Anom Bowalaksono, Dian Ayubi, Sarah Islamiati Pertiwi Dec 2022

Urban Farming: Empowerment To Increase Economic, Education, And Nutritional Benefit For The Sub-Urban Community, Nasruddin Nasruddin, Yusuf Donner Dwiyantama, Banu Muhammad, Anom Bowalaksono, Dian Ayubi, Sarah Islamiati Pertiwi

ASEAN Journal of Community Engagement

This article discusses the urban farming program at Sekolah Master in Beji, Depok, Indonesia, which aims to provide the community with broader benefits, such as economy, education, and increased nutritional value. The project involves planting method that was introduced to this school community. The program itself consists of several stages, starting from the preparation—dissemination of the program and designing a plan for the greenhouse, the implementation—constructing the greenhouse and installing the automatic water system, planting the vegetation, and monitoring and evaluation of the program. Eventually, an evaluation of the successful program is required to determine whether the program can be …


Bio-Based Fire Retardant For Coco Lumber Using Aloe Barbadensis Miller (Aloe Vera), Mangifera Indica (Mango), Or Persea Americana (Avocado) And Boron Additives, Hannah Luisa B. Mallillin, John Gabriel B. Bolivar, Niccolo Armando C. De Castro, Seo Eun Kim, Isabel Angelica A. Sanchez, Antonio Agustin F. Singian, Zaki Mitzrael L. Santos, Esther Joy G. Valle, Jose Mari M. Calamlam, Gerald B. Gamboa Dec 2022

Bio-Based Fire Retardant For Coco Lumber Using Aloe Barbadensis Miller (Aloe Vera), Mangifera Indica (Mango), Or Persea Americana (Avocado) And Boron Additives, Hannah Luisa B. Mallillin, John Gabriel B. Bolivar, Niccolo Armando C. De Castro, Seo Eun Kim, Isabel Angelica A. Sanchez, Antonio Agustin F. Singian, Zaki Mitzrael L. Santos, Esther Joy G. Valle, Jose Mari M. Calamlam, Gerald B. Gamboa

Sinaya: A Philippine Journal for Senior High School Teachers and Students

Accidental fires are prevalent in low-income communities and one of the solutions to decrease fire risk is to apply fire retardants on combustible materials. While extensive research was available in creating fire retardants with inorganic chemicals, further studies are needed for bio-based fire retardants. The development of bio-based fire retardants involves testing organic matter for the presence of fire-retardant compounds such as nitrogen, phosphorus, and polyphenols. This study sought to determine the effectiveness of the peels of Aloe barbadensis miller (aloe vera), Mangifera indica (mangoes), and Persea americana (avocados) in creating bio-based fire retardants for coco lumber. Maceration was used …


Religiosity And Organizational Citizenship Behavior (Ocb) In Supporting Community Engagement During The Covid-19 Pandemic: Work From Home (Wfh) And Work From Office (Wfo), Desprina Octaffiani, Evony Silvino Violita Dec 2022

Religiosity And Organizational Citizenship Behavior (Ocb) In Supporting Community Engagement During The Covid-19 Pandemic: Work From Home (Wfh) And Work From Office (Wfo), Desprina Octaffiani, Evony Silvino Violita

Journal of Environmental Science and Sustainable Development

Pandemic COVID-19 that is currently faced by all countries has changed the wheels of workers' lives in all sectors. Keeping work performance in good quality is needed to in improving company performance. One way that is considered important to maintain the performance of the workforce is by voluntary social support received from co-workers or what is called Organizational Citizenship Behaviour (OCB). This study examines the correlation o of job satisfaction and religiosity on OCB behaviour. Because while religious belief and the level of religiosity are an important part of a person's life, many studies have been conducted to test this., …


Foreword From Handling Editor - 9th Edition, Ahyahudin Sodri Dec 2022

Foreword From Handling Editor - 9th Edition, Ahyahudin Sodri

Journal of Environmental Science and Sustainable Development

We are delighted to present the 9th edition of JESSD, published in December 2022. We have selected thirteen of the best articles for this edition that related with topic of Environmental Science and Sustainable Development.


Performance Investigations Of The Charging And Discharging Processes In A 3-Tank Thermal Energy Storage System, Swalehe Tusiime, Karidewa Nyeinga, Denis Okello, Ole J. Nydal Dec 2022

Performance Investigations Of The Charging And Discharging Processes In A 3-Tank Thermal Energy Storage System, Swalehe Tusiime, Karidewa Nyeinga, Denis Okello, Ole J. Nydal

Tanzania Journal of Science

The paper presents a 3 tank thermal energy storage system. The system consists of cold oil reservoir, heat storage tank, and a residual drainage tank. Cold oil flows by gravity into a heating chamber and after being heated to the required temperature, a mechanical thermostat opens allowing the hot oil to flow into a heat storage tank. The storage tank was discharged through the cooking unit by boiling 0.5 litres of water. The used oil flowed by gravity to the drainage tank. The discharge flow rates of 0.5, 2.1, 2.8 and 6.5 g/s were considered. A charging efficiency of 51.3% …


Phytochemical And Antibacterial Evaluations Of Chloroform Extract Of Mondia Whitei (Hook F) Skeels, Abdullahi Shehu, Ojochide Inikpi Egwemi, Olufunmilayo Adeola Ajayi, Abdulmumeen Amao Hamid Dec 2022

Phytochemical And Antibacterial Evaluations Of Chloroform Extract Of Mondia Whitei (Hook F) Skeels, Abdullahi Shehu, Ojochide Inikpi Egwemi, Olufunmilayo Adeola Ajayi, Abdulmumeen Amao Hamid

Tanzania Journal of Science

Mondia whitei, also known as Mondia, is an aromatic plant of Apocynaceae family. It is used as aphrodisiac, antidepressant, fertility medication and to improve appetite. The present study aimed to evaluate the phytochemical and antibacterial properties of the plant. The chloroform extract of M. whitei was screened for its antibacterial effects using agar diffusion method against five bacterial strains (Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae and Salmonella typhi). The extract was active against S. typhi, K. pneumoniae and S. aureus at 400, 400 and 200 mg/mL, respectively. The antibacterial activity of the extract was observed in a dose-dependent …


Impacts Of Climate Change On Small Pelagic Fish Catches In The Coastal Artisanal Fishers Communities Of Tanzania, Lyidia Kapapa, Paul Onyango Onyango, Nibedita Mukherjee, Prosper Mfilinge Dec 2022

Impacts Of Climate Change On Small Pelagic Fish Catches In The Coastal Artisanal Fishers Communities Of Tanzania, Lyidia Kapapa, Paul Onyango Onyango, Nibedita Mukherjee, Prosper Mfilinge

Tanzania Journal of Science

Climate-related effects occur across all regions in Tanzania, affecting primary sectors such as agriculture and fishing. This study investigated the impacts of climatic change on small pelagic catches in fishers in Kilindoni, Kipumbwi and Kilwa Kivinje villages along the Tanzanian coast. We studied how changes in rainfall, sea surface temperature, wind speed and chlorophyll a affect small pelagic fisheries using primary and secondary data. Qualitative and quantitative methods were applied. Primary data collection involved questionnaires, focus group discussions and key informant interviews. Secondary data was obtained from Tanzania Meteorological Agency and remote sensing from Modi's sensor. Results showed an increase …


Diet Of The Golden Jackal (Canis Aureus) And Silver-Backed Jackal (Canis Mesomelas) In The Southern Part Of The Serengeti Ecosystem, Tanzania: A Comparative Study, Steven E. Temu, Cuthbert L. Nahonyo, Marion L. East, Patricia D. Moehlman Dec 2022

Diet Of The Golden Jackal (Canis Aureus) And Silver-Backed Jackal (Canis Mesomelas) In The Southern Part Of The Serengeti Ecosystem, Tanzania: A Comparative Study, Steven E. Temu, Cuthbert L. Nahonyo, Marion L. East, Patricia D. Moehlman

Tanzania Journal of Science

Habitat and food resource partitioning are predicted to facilitate the coexistence of similar-sized carnivores. The golden jackal (Canis aureus) and silver-backed jackal (Canis mesomelas) are similar-sized canids that respectively inhabit grassland and woodland in the Serengeti ecosystem, Tanzania. As information on the diet and food-intake of these two species in this ecosystem is limited, we aimed to compare the diet and food-intake of these canids in the wet and dry seasons, using data from focal samples of foraging behaviour and scat analysis. We predicted dietary differences between these species, seasonal differences within species and peak food intake when breeding. Result …


Chemical Analysis, Antibacterial Activities And Uses Of Leaves And Calyces Of Hibiscus Sabdariffa Grown In Dodoma, Tanzania, Sartaz Begum, Derick R. Mwakimbwala, Gideon Sangiwa, Valence M.K. Ndesendo Dec 2022

Chemical Analysis, Antibacterial Activities And Uses Of Leaves And Calyces Of Hibiscus Sabdariffa Grown In Dodoma, Tanzania, Sartaz Begum, Derick R. Mwakimbwala, Gideon Sangiwa, Valence M.K. Ndesendo

Tanzania Journal of Science

Preliminary phytochemical screening of aqueous and ethanolic extracts of Hibiscus sabdariffa grown in Tanzania revealed the presence of secondary metabolites like steroids, tannins, saponins, glycosides, terpenoids, flavonoids along with L-ascorbic acid (vitamin C) and iron(II). Furthermore, both leaves and calyces showed antibacterial activities (agar well diffusion method) against selected bacterial species (Escherichia coli, Staphylococcus aureus, Salmonella typhi and Shigella sonnei), but calyces possessed potent antibacterial activities compared to leaves. The results also supported the claimed traditional uses of this plant. When interrogated during the cross-sectional study in Dodoma region, 54% of the respondents claimed the plant is used to treat …


Enhancing Germination Of Seeds Of A Multipurpose Tree Species Combretum Molle, Samora Macrice Andrew Dec 2022

Enhancing Germination Of Seeds Of A Multipurpose Tree Species Combretum Molle, Samora Macrice Andrew

Tanzania Journal of Science

Combretum molle R. Br. ex G. Don (Combretaceae) is a highly valued indigenous multipurpose tree species that has gained considerable attention in recent times due to its importance as a medicinal plant as well as an alternative species for wood and charcoal production. However, we lack adequate information on simple and appropriate methods that could be used to break its distinct seed dormancy to support domestication of wild populations apparently undergoing over exploitation and the negative impacts of deforestation. Eight pre-treatment methods involving complete removal of wing, complete removal of mesocarp, overnight soaking in cold water (24 °C) and partial …


Oral Impacts On Daily Performances Among People Living With Human Immunodeficiency Virus On Haart Era Attending Care And Treatment Clinics In Dar Es Salaam, Tanzania, Leonard Evarist, Irene Kida Minja Dec 2022

Oral Impacts On Daily Performances Among People Living With Human Immunodeficiency Virus On Haart Era Attending Care And Treatment Clinics In Dar Es Salaam, Tanzania, Leonard Evarist, Irene Kida Minja

Tanzania Journal of Science

Oral disease/conditions are reported to have negative effects on the quality of life of People Living with Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (PLWHIV/AIDS). This study aimed to assess the prevalence and causes of oral impacts on daily performances (OIDP) and its associated factors among PLWHIV/AIDS. A cross-sectional study was conducted among 218 PLWHIV/AIDS attending two HIV Care and Treatment Centres (CTCs) in Dar es Salaam. The study utilized a structured interview schedule containing questions on socio-demography and a single item of global oral health measure on the perception of current oral health status (OHS). A Swahili version of an …


Antibacterial Potency Of Allium Sativum, Psidium Guajava, Zingiber Officinale Roots Against The Food Poisoning Strains (Escherichia Coli 0157:H7 And Staphylococcus Aureus), Godfrey O. Mauti Dec 2022

Antibacterial Potency Of Allium Sativum, Psidium Guajava, Zingiber Officinale Roots Against The Food Poisoning Strains (Escherichia Coli 0157:H7 And Staphylococcus Aureus), Godfrey O. Mauti

Tanzania Journal of Science

Escherichia coli 0157:H7 and Staphylococcus aureus are notorious food poisoning bacteria of great effect on human health. This study determined the phytochemical constituents of ethanolic, vacuum liquid chromatography (VLC) filtrates of Allium sativum (garlic), Psidium guajava (guava), Zingiber officinale (ginger) and their antibacterial activities on E. coli 0157:H7 and S. aureus. In a laboratory-based controlled experiment, the antibacterial and inhibitory activities of the VLC filtrates in doses of 0.01, 0.02, 0.04, and 0.08g/mL were investigated on E. coli 0157:H7 and S. aureus using the agar well diffusion method and compared with a standard antibiotic. The indices of the zone of …


Phytochemical Constituents, Haematological Activities And Gc-Ms Analysis Of Isolated Oil Of Rosary Pea (Abrus Precatorius) In Wistar Rat Fed With High Lipid Diet, Osaro Iyekowa, Opara V Ndubuisi Dec 2022

Phytochemical Constituents, Haematological Activities And Gc-Ms Analysis Of Isolated Oil Of Rosary Pea (Abrus Precatorius) In Wistar Rat Fed With High Lipid Diet, Osaro Iyekowa, Opara V Ndubuisi

Tanzania Journal of Science

The study is aimed at investigating the phytochemical constituents and haematological activities of the isolated oil in Wistar rat fed with high lipid diet. Powdered leaves of Abrus precatorious were extracted and phytochemical screening was done according to prescribed standard methods, while vacuum liquid chromatography (VLC) was adopted for oil isolation of the crude extract and characterized by gas chromatography-mass spectrometry (GC-MS). Thirty adult Wistar rats were randomly arranged into six groups (A, B, C, D, E and F) and treated under certain conditions. Haematological analyses were performed according to standard procedures. Saponins, alkaloids, terpenoids, flavonoids and glycosides were present. …


Morphological Variabilities And Identification Of Yam (Dioscorea Spp.) Genotypes From Major Growing Regions In Tanzania, Joseph I Massawe, Gladness E Temu Dec 2022

Morphological Variabilities And Identification Of Yam (Dioscorea Spp.) Genotypes From Major Growing Regions In Tanzania, Joseph I Massawe, Gladness E Temu

Tanzania Journal of Science

Yam (Dioscorea spp.) is a vegetatively propagated crop that belongs to the family Dioscoreaceae. In Tanzania, yam is mainly grown as a source of food and income generation, especially for smallholder farmers. In this study, an assessment of morphological variations among 74 genotypes of Dioscorea spp. collected from six major growing regions was conducted. Yam genotypes were maintained and planted at Tanzania Agricultural Research Institute-Kibaha for characterization. Data from fifty morphological variables were subjected to multivariate analysis using principal component analysis and cluster analysis. The first nine principal components with Eigenvalues > 1 accounted for 86.28% of the total variations. Some …


Determination Of Sugars, Amino Acids, Ph And Alcohol In Bamboo Beverage From Southern Highlands, Tanzania, Lilian D Kaale Dec 2022

Determination Of Sugars, Amino Acids, Ph And Alcohol In Bamboo Beverage From Southern Highlands, Tanzania, Lilian D Kaale

Tanzania Journal of Science

The amounts of sugars and amino acids play significant roles in defining the fermentation process and quantifying the alcohol levels in beverages, while pH affects the biological stability, colour, oxidation rate, and protein stability of alcoholic beverages. This study investigated the sugar content, amino acids, alcohol levels, and pH of bamboo beverage from Tanzania's southern highlands. During storage, the sugars significantly decreased (p < 0.05), especially when kept at room temperature from 52.96 to 0.00 (source 1), 53.35 to 0.00 (source 2) and 53.57 to 0.00 (source 3) g/L for fructose, from 47.93 to 14.78 (source 1), 47.23 to 14.91 (source 2) and 47.61 to 14.77 (source 3) g/L for glucose, and from 0.40 to 0.00 (source 1), 0.36 to 0.00 (source 2) and 0.37 to 0.00 (source 3) g/L for sucrose after six days of storage. A total of 15 amino acids were determined from the bamboo beverage with tyrosine being the most prevalent (597.68 mg/L for source 1, 599.44 mg/L for source 2 and 597.83 mg/L for source 3), followed by valine (261.13 mg/L for source 1, 261.24 mg/L for source 2 and 262.54 mg/L for source 3), threonine (76.69 mg/L for source 1, 76.91 mg/L for source 2 and 77.13 mg/L for source 3), and serine (66.37 mg/L for source 1, 67.23 mg/L for source 2 and 66.68 mg/L for source 3). After six days of storage at room temperature, there was a significant decrease in pH from 4.04 to 3.63. Alcohol content ranged from 3.11 to 9.05% v/v at the room temperature storage. These results might facilitate the optimal use of bamboo beverages, which have been neglected due to lack of scientific information such as amino acid and sugar levels. Keywords:    Bamboo beverage, ulanzi, amino acids, sugars, alcohol content.


Antimalarial And Antimicrobial Activities Of Some Heteroleptic Metal(Ii) Complexes Of Sulfadiazine–Vitamin C: Synthesis And Spectroscopic Studies, Ikechukwu P. Ejidike, Mercy O. Bamigboye, Dorcas A. Fadare, Juliana B. Adetunji, Joshua A. Obaleye Dec 2022

Antimalarial And Antimicrobial Activities Of Some Heteroleptic Metal(Ii) Complexes Of Sulfadiazine–Vitamin C: Synthesis And Spectroscopic Studies, Ikechukwu P. Ejidike, Mercy O. Bamigboye, Dorcas A. Fadare, Juliana B. Adetunji, Joshua A. Obaleye

Tanzania Journal of Science

Some new Ni(II), Zn(II), Co(II), Cu(II), and Cd(II) of mixed Sulphadiazine and Vitamin C complexes have been synthesized and characterized by different spectroscopic techniques such as FT-IR, elemental analysis, molar conductivity, and magnetic measurements. Both ligands used for this research work act as bidentate ligands towards the central metal ions coordinating through the nitrogen atoms of >C=N–, NH2 groups of Sulphadiazine and oxygen atoms of OH, CO groups of Vitamin C. Tetrahedral and square-planar geometries have been proposed for the complexes. The complexes are stable under atmospheric conditions. The ligands and their complexes were screened for antimicrobial activities against some …


Fool Me Once: Characterizing The Response Of Notophthalmus Viridescens To Multiple Exposures Of Batrachochytrium Salamandrivorans, Julia A. Mccartney Dec 2022

Fool Me Once: Characterizing The Response Of Notophthalmus Viridescens To Multiple Exposures Of Batrachochytrium Salamandrivorans, Julia A. Mccartney

Graduate Masters Theses

The repertoire of defenses a host may use against a pathogen is often thought of in the context of innate and adaptive immunity. However, the role of host symbionts such as the microbiome are being examined potentially as part of an individual’s defense against disease. Chytridiomycosis, caused by the fungal pathogens Batrachochytrium dendrobatidis (Bd) and Batrachochytrium salamandrivorans (Bsal), is characterized by an infection of the skin often leading to osmotic imbalance and mortality, and has resulted in losses in global amphibian biodiversity. Understanding what may influence the development of resistance to or tolerance of infection is critical to developing prevention …


Host-Pathogen Interactions In A Changing World: Microbes, Mucosal Defenses, And Multiple Hosts, Brandon C. Labumbard Dec 2022

Host-Pathogen Interactions In A Changing World: Microbes, Mucosal Defenses, And Multiple Hosts, Brandon C. Labumbard

Graduate Doctoral Dissertations

As fungal diseases continue to emerge, research increasingly focuses on host-microbiome interactions and links to disease. Certain skin-associated microbes may benefit hosts by protecting them from invading pathogens. Seasonal changes in the host environment can also result in shifts in the microbial community and pathogen virulence – potentially influencing disease dynamics. I investigated how cutaneous microbial communities differ across hosts, seasons, and Batrachochytrium dendrobatidis (Bd) infection status by sequencing the microbial communities of 1,100 leopard frogs at five locations across the US. Percent anti-Bd function varied seasonally and with Bd infection status. Bacterial communities also varied across locations and time. …


Quantifying Life History Energetics Of An Oviparous Elasmobranch Subject To Future Warming Water, Carolyn R. Wheeler Dec 2022

Quantifying Life History Energetics Of An Oviparous Elasmobranch Subject To Future Warming Water, Carolyn R. Wheeler

Graduate Doctoral Dissertations

Marine ectothermic fishes – fishes that do not regulate internal body temperature independent from the water temperature – are some of the most vulnerable organisms to rapid and alarming increases in environmental temperature occurring due to climate change mediated-ocean warming. For tropical fish species that live near their thermal maxima, this warming could be of grave consequence to individuals, populations, and whole marine ecosystems. Certain key life stages such as embryos and reproducing adults may be particularly vulnerable to warming given the excess energetic costs of these life stages, which may disallow compensation for extreme changes in temperature. One taxonomic …


Application Of Mobilenets Convolutional Neural Network Model In Detecting Tomato Late Blight Disease, Richard C Rajabu, Juma S Ally, Jamal F Banzi Dec 2022

Application Of Mobilenets Convolutional Neural Network Model In Detecting Tomato Late Blight Disease, Richard C Rajabu, Juma S Ally, Jamal F Banzi

Tanzania Journal of Science

Late blight (LB) disease causes significant annual losses in tomato production. Early identification of this disease is crucial in halting its severity. This study aimed to leverage the strength of Convolutional Neural Networks (CNNs) in automated prediction of tomato LB. Through transfer learning, the MobileNetV3 model was trained on high-quality, well-labeled images from Kaggle datasets. The trained model was tested on different images of healthy and infected leaves taken from different real-world locations in Mbeya, Arusha, and Morogoro. Test results demonstrated the model's success in identifying LB disease, with an accuracy of 81% and a precision of 76%. The trained …


Effects Of Long Acting Oxytetracycline On Contagious Bovine Pleuropneumonia Experimentally Infected Cattle, Beatrice Otina, Philip Kitala, Moses Olum, Alexander Kipronoh, Lizzie Chesang’, Kristin Stuke, Hezron Wesonga Dec 2022

Effects Of Long Acting Oxytetracycline On Contagious Bovine Pleuropneumonia Experimentally Infected Cattle, Beatrice Otina, Philip Kitala, Moses Olum, Alexander Kipronoh, Lizzie Chesang’, Kristin Stuke, Hezron Wesonga

Tanzania Journal of Science

Contagious bovine pleuropneumonia is an important disease of cattle. Many strategies employed for its eradication and control have had shortcomings. This study was conducted to determine the effects of long acting Oxytetracycline on its course. The study involved 30 indigenous zebu cattle sourced from an area free of the disease, infected by contact transmission and randomly allocated to Oxytetracycline or saline treatment groups. Clinical observations were recorded on the two groups concurrently. Cattle were tested for the disease using complement fixation test. The mean clinical scores of the groups for each observation was compared post treatment on GENSTAT using unpaired …


Impacts Of Dietary Chrysophyllum Albidum Fruit Pulp On Brain Cholinesterase Function In High-Fat Diet/Streptozotocin-Induced Diabetic Rats, Seun Funmilola Akomolafe, Sunday Idowu Oyeleye, Ifeoluwa Adebayo Odeniyi, Iyabo Folake Oladapo, Ayodele Jacob Akinyemi, Folake Lucy Oyetayo, Olubunmi Bolanle Ajayi Dec 2022

Impacts Of Dietary Chrysophyllum Albidum Fruit Pulp On Brain Cholinesterase Function In High-Fat Diet/Streptozotocin-Induced Diabetic Rats, Seun Funmilola Akomolafe, Sunday Idowu Oyeleye, Ifeoluwa Adebayo Odeniyi, Iyabo Folake Oladapo, Ayodele Jacob Akinyemi, Folake Lucy Oyetayo, Olubunmi Bolanle Ajayi

Tanzania Journal of Science

Epidemiologic studies have shown strong correlations between Alzheimer’s disease and diabetes mellitus. The exact mechanism through which this happens remains unclear. However, the dependence on glucose for brain function has been proposed as one possible mechanism. Hence, this study investigated the neuroprotective potential of Chrysophyllum albidum fruit pulp (CAPP) with hypoglycaemic properties in diabetic rats induced with high-fat diet/streptozotocin (STZ). The animals were grouped into seven units as follows: control, STZ-induced, STZ + metformin (positive control), STZ + 5% CAPP, STZ + 10% CAPP, control + 5% CAPP and control + 10% CAPP and each group was made up of …


Advancing The Potential Of Pet And Pp-Based Beverage Packaging To Support Circular Economy, Dini Trisyanti, Khair Ranggi Laksita Wengi, Rizka Legita Rachmawati, Rangga Akib Dec 2022

Advancing The Potential Of Pet And Pp-Based Beverage Packaging To Support Circular Economy, Dini Trisyanti, Khair Ranggi Laksita Wengi, Rizka Legita Rachmawati, Rangga Akib

Journal of Environmental Science and Sustainable Development

With around 5.6 million tons of annual plastic consumption and merely 7 percent plastic recycling rate, Indonesia is facing a plastic pollution crisis. The recent progress of Indonesia’s recycling industries has provided an asset to address this crisis. In 2017, the domestic post-consumption plastic waste could only fulfil around 24 percent the domestic needs for recycled plastic, which stands at 1.65 million ton/year. Leveraging the plastic waste ‘asset’ through circular economy can fill this demand gap. A five-month study was conducted to analyse the recycling rate of Polyethylene terephthalate (PET) and Polypropylene (PP)-based beverage plastic packaging in Greater Jakarta Metropolitan …


Effect Of Neoadjuvant Chemotherapy On Intraoperative Core Temperature In Patients With Breast Cancer: A Retrospective Cohort Study, Daniel D Kim, Sarah M Desnyder, Patrick M Dougherty, Juan P Cata Dec 2022

Effect Of Neoadjuvant Chemotherapy On Intraoperative Core Temperature In Patients With Breast Cancer: A Retrospective Cohort Study, Daniel D Kim, Sarah M Desnyder, Patrick M Dougherty, Juan P Cata

Faculty, Staff and Student Publications

BACKGROUND: Clinical evidence suggests that chemotherapeutic agents are associated with neuropathy and peripheral autonomic dysfunction. However, the possible effects of neoadjuvant chemotherapy on intraoperative temperature remain poorly characterised.

METHODS: We evaluated patients who underwent a mastectomy for breast cancer between April 2016 and July 2020. Propensity scores were used to match patients who received neoadjuvant chemotherapy with those who did not, and intraoperative core temperature patterns were analysed in the matched cohort. The independent associations between vasopressor use and heart rate during general anaesthesia in the matched cohort were also analysed.

RESULTS: Data from 1764 patients were analysed (882 patients …


Loss Of Ubiquitin-Specific Peptidase 18 Destabilizes 14-3-3Ζ Protein And Represses Lung Cancer Metastasis, Zibo Chen, Lin Zheng, Yulong Chen, Xiuxia Liu, Masanori Kawakami, Jason Roszik, Ralph E Parchment, Xin Liu, Thorkell Andresson, Gerard Duncan, Jonathan M Kurie, Jaime Rodriguez-Canales, Xi Liu, Ethan Dmitrovsky Dec 2022

Loss Of Ubiquitin-Specific Peptidase 18 Destabilizes 14-3-3Ζ Protein And Represses Lung Cancer Metastasis, Zibo Chen, Lin Zheng, Yulong Chen, Xiuxia Liu, Masanori Kawakami, Jason Roszik, Ralph E Parchment, Xin Liu, Thorkell Andresson, Gerard Duncan, Jonathan M Kurie, Jaime Rodriguez-Canales, Xi Liu, Ethan Dmitrovsky

Faculty, Staff and Student Publications

Cancer metastasis is a major cause of cancer-related mortality. Strategies to reduce metastases are needed especially in lung cancer, the most common cause of cancer mortality. We previously reported increased ubiquitin-specific peptidase 18 (USP18) expression in lung and other cancers. Engineered reduction of USP18 expression repressed lung cancer growth and promoted apoptosis. This deubiquitinase (DUB) stabilized targeted proteins by removing the complex interferon-stimulated gene 15 (ISG15). This study explores if the loss of USP18 reduced lung cancer metastasis. USP18 knock-down in lung cancer cells was independently achieved using small hairpin RNAs (shRNAs) and small interfering RNAs (siRNAs). USP18 knock-down reduced …


Habitat Imaging Biomarkers For Diagnosis And Prognosis In Cancer Patients Infected With Covid-19, Muhammad Aminu, Divya Yadav, Lingzhi Hong, Elliana Young, Paul Edelkamp, Morteza Salehjahromi, Sheeba J Sujit, Melissa M Chen, Bradley Sabloff, Gregory Gladish, Patricia M De Groot, Myrna C B Godoy, Tina Cascone, Natalie I Vokes, Jianjun Zhang, Kristy K Brock, Naval Daver, Scott E Woodman, Hussein A Tawbi, Ajay Sheshadri, J Jack Lee, David Jaffray, D Code Team, Carol C Wu, Caroline Chung, Jia Wu Dec 2022

Habitat Imaging Biomarkers For Diagnosis And Prognosis In Cancer Patients Infected With Covid-19, Muhammad Aminu, Divya Yadav, Lingzhi Hong, Elliana Young, Paul Edelkamp, Morteza Salehjahromi, Sheeba J Sujit, Melissa M Chen, Bradley Sabloff, Gregory Gladish, Patricia M De Groot, Myrna C B Godoy, Tina Cascone, Natalie I Vokes, Jianjun Zhang, Kristy K Brock, Naval Daver, Scott E Woodman, Hussein A Tawbi, Ajay Sheshadri, J Jack Lee, David Jaffray, D Code Team, Carol C Wu, Caroline Chung, Jia Wu

Faculty, Staff and Student Publications

OBJECTIVES: Cancer patients have worse outcomes from the COVID-19 infection and greater need for ventilator support and elevated mortality rates than the general population. However, previous artificial intelligence (AI) studies focused on patients without cancer to develop diagnosis and severity prediction models. Little is known about how the AI models perform in cancer patients. In this study, we aim to develop a computational framework for COVID-19 diagnosis and severity prediction particularly in a cancer population and further compare it head-to-head to a general population.

METHODS: We have enrolled multi-center international cohorts with 531 CT scans from 502 general patients and …


Prevalence And Evaluation Of Multidrug Resistance Pattern Of Pseudomonas Aeruginosa Among Critical And Non-Critical Areas At A Tertiary Care Hospital Of Multan, Romah Ishfaq, Hubza Ruatt Khan, Mehvish Javeed, Muhammad Ikrama Tanveer, Asma Ashraf Dec 2022

Prevalence And Evaluation Of Multidrug Resistance Pattern Of Pseudomonas Aeruginosa Among Critical And Non-Critical Areas At A Tertiary Care Hospital Of Multan, Romah Ishfaq, Hubza Ruatt Khan, Mehvish Javeed, Muhammad Ikrama Tanveer, Asma Ashraf

Journal of Bioresource Management

Pseudomonas aeruginosa is an extremely wide spread microorganism linked to nosocomial illnesses. Effective inspection of variations in antimicrobial resistance patterns of P. aeruginosa is vital for selecting suitable antimicrobial drugs for pragmatic treatment. The current research has been performed for assessing antimicrobial sensitivity profile of P. aeruginosa isolated as of a variety of medical specimens collected from critical and non-critical admitted patients of Nishtar Hospital, Multan. The isolates were detected utilizing standard lab practices, as well as the sensitivity was examined employing Kirby-Bauer disk diffusion method corresponding to Clinical and Laboratory Standard Institute (CLSI) recommendations 2019. Out of 373 samples, …


Ecological Diagnosis And Diversity Structure Of The Forest Birds Community In Machroha Forest (Souk Ahras – Northeastern Algeria), Abdelhak Boucif, Mouslim Bara, Moussa Houhamdi Dec 2022

Ecological Diagnosis And Diversity Structure Of The Forest Birds Community In Machroha Forest (Souk Ahras – Northeastern Algeria), Abdelhak Boucif, Mouslim Bara, Moussa Houhamdi

Journal of Bioresource Management

Machroha forest is a large hot spot of biodiversity of northeastern region of Algeria. It is dominated by several species of oak tree that can contribute to the conservation of many animals such as birds. Our study was carried out from February 2019 to July 2021, in order to diagnosis the ecological status of forest birds and their dynamics. Our results reported that this forest was including 19.21% of the Algerian avifauna diversity. We recorded 78 species of birds classified in 32 families. The main species were sedentary with an insectivorous trophic categories and terrestrial guild. Three species observed in …