Life Sciences Commons^™

Soil Quality Assessment And Management, M. G. Kibblewhite

IGC Proceedings (1977-2023)

1. Soil quality is related to the capacity of soil to deliver ecosystem services on a sustainable basis.
2. Effective management of soil within grasslands can deliver many benefits to mankind but poor management may cause loss of soil quality from erosion, loss of organic matter, physical deterioration etc.
3. Services are delivered from soil by biological processes. Soil quality depends on the form and condition of the soil habitat. Fixed factors (e.g. texture) are useful for assigning soil to types. Variable factors (e.g. organic carbon) can then be used to assess quality within soil types, by reference to percentiles of the distribution …

Soil Microbial Community: Understanding The Belowground Network For Sustainable Grassland Management, Y. G. Zhu, W. D. Kong, B. D. Chen, Z. B. Nan, P. Christie

IGC Proceedings (1977-2023)

1. In addition to the use of conventional methodologies in soil microbial research, molecular techniques are now being applied to gain insights into the soil microbial community;
2. Plant diversity can exert impacts on soil microbial diversity (through root activities and plant litter etc.), but may in itself be significantly altered by soil properties;
3. Soil microbial diversity largely determines the stability of soil ecosystems under biotic and abiotic perturbations.
4. Management of soil microbial diversity can only be achieved through better understanding their structures and functions.

Grasslands1 For Production And The Environment, David R. Kemp, David L. Michalk

IGC Proceedings (1977-2023)

1. To manage grasslands for production and enhanced environmental values requires a redefinition of the frameworks within which management decisions are made, and a tailoring of practices to suit the ways that farmers operate.
2. Improving the perenniality and permanence of grasslands usually leads to better environmental and production outcomes.
3. There is a case for a more conservative approach to utilising grasslands in order to sustain the functioning of local ecosystems and to improve water quality, nutrient and energy cycling and biodiversity.
4. A landscape rather than paddock focus is more appropriate for meeting current grassland management objectives. Grasslands can be triaged to …

The Potential Of Grassland And Associated Forages To Produce Fibre, Biomass, Energy Or Other Feedstocks For Non-Food And Other Sectors: New Uses For A Global Resource, M. F. Askew

IGC Proceedings (1977-2023)

1. In developed countries increased areas of land will become available for non-food production. Recent reforms of the Common Agricultural Policy will further intensify this trend in Europe.
2. There is potential for grassland and associated species to contribute to large tonnage markets of energy and bulk fibres, to the supply of fermentation products and to speciality markets, but processes and approaches to the market are not as yet developed.
3. There is potential for the establishment of Graminaceous species - specifically for non- food use. For European conditions particular attention is being given to Miscanthus sinensis (Miscanthus), Arundo donax (Giant Reed), Phalaris …

Grasses As Biofactories: Scoping Out The Opportunities, Nick Roberts, K. Richardson, G. Bryan, Christine R. Voisey, W. Mcnabb, T. Conner, M. Christey, R. Johnson

IGC Proceedings (1977-2023)

1. Plant biopharming is set to dominate commercial recombinant protein expression for specific proteins.
2. The choice of plant species depends on a multitude of factors and is determined on a case- by-case basis.
3. As a leaf based expression system grasses would have to compete predominantly with tobacco and alfalfa.
4. The grass-endophyte symbiosis offers a number of unique possibilities for biopharming.

Adoption Of Tropical Legume Technology Around The World: Analysis Of Success, H. M. Shelton, Steven Franzel, M. Peters

IGC Proceedings (1977-2023)

1. Examples of successful adoption of forage legumes are reported from all continents, where they delivered profitability and often provided multipurpose benefits to farmers.
2. Factors vital to successful adoption were: meeting the needs of farmers; building relevant partnerships; understanding the socio-economic context and skills of farmers; participatory involvement with rural communities; and long-term involvement of champions.
3. Organisation of seed supply, achieving scale-up and forming partnerships to implement adoption are key features.
4. Legumes remain an important but under-exploited resource for tropical farming systems. The alternative to legumes will be greater and more costly use of N-fertilisers and purchased protein concentrates.
5. The R&D …

Evolution Of Integrated Crop-Livestock Production Systems, Martin H. Entz, William D. Bellotti, J. M. Powell, S. V. Angadi, W. Chen, K. H. Ominski, B. Boelt

IGC Proceedings (1977-2023)

1. Many factors contribute to changes in the crop-livestock systems, but no logical end-point in the evolution process exists.
2. While benefits of integrated crop-livestock systems over specialised crop and livestock systems are well documented, there has been a move to specialised crop and livestock production.
3. Sustainability issues (manure nutrient concentration, soil quality maintenance, salinity, herbicide resistance, economic instability) have created a renewed interest in integrated crop-livestock systems.
4. Farmer adaptability is as an important link in the evolution between ‘states of integration’.

Overcoming Seasonality Of Production: Opportunities Offered By Forage Conservation Technologies, P. O'Kiely, A. G. Kaiser

IGC Proceedings (1977-2023)

1. Seasonality of forage supply is a key contributor to the seasonality of meat and milk production.
2. Conserving forages as silage or hay can help reduce the seasonality of feed supply.
3. Forage conservation technologies make this contribution mainly through increases in the yield or quality of suitable crops, through an improved efficiency of the conservation process or by allowing a reduction in costs.
4. Future research needs differ considerably among regions of the world.

Strategies To Mitigate Seasonality Of Production In Grassland-Based Systems, Claudio Porqueddu, S. Maltoni, J. G. Mcivor

IGC Proceedings (1977-2023)

1. Fertilisation use and manipulation can cost-effectively alter species composition, increase seasonal herbage production and improve herbage quality.
2. Choice of suitable grassland species, varieties and mixtures offers opportunity to mitigate limitations of seasonal grassland production.
3. Special purpose fodder crops, cereals, shrubs and trees offer alternative or supplementary feed sources.
4. Manipulation of stocking rates, grazing systems, transhumance and pasture management at various times of the season are significant advantageous options.
5. Integration of different strategies is essential to mitigate seasonality in systems of animal production that must be inherently more sustainable over a longer time frame.

Interactions Between Foraging Behaviour Of Herbivores And Grassland Resources In The Eastern Eurasian Steppes, Deli Wang, Guodong Han, Yuguang Bai

IGC Proceedings (1977-2023)

1. In rangeland areas such as the eastern Eurasian steppes (Mongolia and China), foraging behaviour is influenced by plant or vegetation properties with high heterogeneity.
2. Until recently foraging theory has not accounted for the foraging process or ingestive behaviour. Existing theories on foraging behaviour need to evolve and begin to coalesce, and combine with observations or manipulative experiments.
3. Plant and patch properties such as diversity and height influence animal foraging behaviour (related to foraging process or diet selection) in heterogeneous steppes.
4. Stocking rate is the most important management factor for grazing or vegetation management, and determining the optimal stocking rate in …

Foraging Behaviour And Herbage Intake In The Favourable Tropics/Sub-Tropics, S. C. Da Silva, Paulo C. De F. Carvalho

IGC Proceedings (1977-2023)

1. Herbage intake by animals grazing tropical/sub-tropical pastures is directly related to bite mass, as it is for those grazing temperate pastures.
2. Where these swards have low proportions of stem and dead material (controlled swards), herbage intake follows a similar pattern to that of temperate pasture species, but leaf characteristics, such as lamina length play an important role and influence the short-term rate of intake.
3. Sward structural characteristics and behavioural factors are relatively more important than nutritional factors in terms of herbage intake regulation. The feeding value of the herbage produced is potentially adequate to sustain high levels of beef cattle …

The Effectiveness Of A Religiously Framed Hpv Vaccination Message Among Christian Parents Of Unvaccinated Adolescents In The United States, Ayokunle Olagoke, Jennifer Herbert-Beirne, Brenikki Floyd, Rachel Caskey, Andrew D. Boyd, Yamilé Molina

Health and Kinesiology Faculty Publications

Background: The uptake of the human papillomavirus (HPV) vaccines has been controversial among religious parents due to beliefs that their children are expected to practice sexual purity and so do not need protection from a sex-related infection. Also, if at all they get infected in the future, God can protect them from sickness without a vaccine. Yet, most HPV vaccination messages are secular, lacking spiritual themes. This study compared the effectiveness of the Centers for Disease Control and Prevention (CDC) Vaccine Information Statement (VIS) on HPV with our intervention message- a scripture-embedded HPV vaccination message (using a randomized controlled …

Differential Strain-Dependent Ovarian And Metabolic Responses In A Mouse Model Of Pcos, April K. Binder, Danielle L. Peecher, Amanda J. Qvigstad, Silvia D. Gutierrez, Jennifer Magaña, David B. Banks, Kenneth S. Korach

Biology Faculty Scholarship

Several mouse models have been developed to study polycystic ovarian syndrome (PCOS), a leading cause of infertility in women. Treatment of mice with dihydrotestosterone (DHT) for 90-days causes ovarian and metabolic phenotypes similar to women with PCOS. We used this 90-day DHT treatment paradigm to investigate the variable incidence and heterogeneity in two inbred mouse strains, NOD/ShiLtJ and 129S1/SvlmJ. NOD mice naturally develop type 1 diabetes, and recent meta-analysis found increased androgen excess and PCOS in women with type 1 diabetes. 129S1 mice are commonly used in genetic manipulations. Both NOD and 129S1 DHT treated mice had early vaginal opening, …

Forecasting Table Beet Root Yield Using Spectral And Textural Features From Hyperspectral Uas Imagery, Mohammad Saif, Robert Chancia, Sarah Pethybridge, Sean Murphy, Amir Hassanzadeh, Jan Van Aardt

Articles

New York state is among the largest producers of table beets in the United States, which, by extension, has placed a new focus on precision crop management. For example, an operational unmanned aerial system (UAS)-based yield forecasting tool could prove helpful for the efficient management and harvest scheduling of crops for factory feedstock. The objective of this study was to evaluate the feasibility of predicting the weight of table beet roots from spectral and textural features, obtained from hyperspectral images collected via UAS. We identified specific wavelengths with significant predictive ability, e.g., we down-select >200 wavelengths to those spectral indices …

What Drives Larval Condition For Northern Anchovy (Engraulis Mordax)? Implications For Coastal Pelagic Species Recruitment Fluctuations And Fishery Management Practices, Michelle Robidas

Theses

Discerning the causes of population boom and bust cycles for coastal pelagic species (CPS) has been a major focus of fisheries management research for over a century. Year-class strength is contingent on larval survival and condition, which can be influenced by larval size at age and growth rate. These two factors, in turn, can be affected by maternal investment and environmental variables such as water temperature, salinity, oxygen, and chlorophyll a. We evaluated each of these factors from 127 two to eight week-old Northern Anchovy (Engraulis mordax) larvae off the coast of San Diego to San Francisco, …

The Immune Modulation On Innate Immunity, From Pathogen Recognition To Fungal Clearance., Ko-Wei Liu

Dartmouth College Ph.D Dissertations

The human lung is not sterile but a complex environment with various microorganisms. Besides commensals in the lung, hundreds to thousands of individual microbiomes enter the lung every day but without causing the symptom. Host innate immunity plays an important role in maintaining homeostasis of the lung environment and as the first defense line against pathogens. Aspergillus fumigatus (A. fumigatus) is a saprophytic filamentous fungus that can cause human disease in immune compromised patients. However, with functional innate immunity, immune cells can quickly recognize pathogen associated molecular patterns (PAMPs) from A. fumigatus through pattern recognition receptors (PRRs). The activation of …

Plastivore: Identification And Functional Characterization Of Plastic Degrading Lipase And Carboxylesterase Enzyme Families From Galleria Mellonella, Joseph Boctor

Theses and Dissertations

[provided as attachment while patent is pending]

Computational Identification Of Circulating Micrornas Associated With The Early Stage Of Ovarian Cancer, Ahmed Abdelrahman El Hosseiny

Theses and Dissertations

Background: Ovarian cancer is the leading cause of death among gynaecological malignancies. Its high fatality rate is due to the difficulty of early detection. Current screening methods are inadequate, and therefore, a new less-invasive early detection method is urgently needed. MicroRNAs are promising biomarker candidates for cancer detection, however, their potential for early detection use is understudied. Aim of the work: We sought to identify sensitive and selective microRNA markers for early diagnosis of ovarian cancer from blood serum samples through computational analysis. Methods: In this investigation, we used bioinformatic methods to analyze MicroRNA-Seq data obtained from public databases for …

Lignin Nanoparticles Comparative Study For Their Emulsifying, Antibacterial And Antioxidant Properties, Matta Asaad Mesak Ebaid

Theses and Dissertations

Converting lignin, the second most natural abundant polymer on earth, into lignin nanoparticles (LNPs) form has potential applications. LNPs’ emulsifying, antibacterial and antioxidant properties of three different lignins, softwood kraft lignoboost (LB), hardwood birch (BB) and alkali protobind 1000 (PB) were evaluated in a comparative study at different pH and concentrations. Lower ionic strength of 5 millimole (mM) citric acid (CA) and pH of 7 were found to be the most optimum conditions for emulsion formation. Comparison among the two homogenization techniques revealed that microfluidizer is favored in case of BB- and PB-LNPs based emulsions, while ultrasonication is optimum in …

Lnc-Uc147 Is Associated With Disease Stage Of Liver, Gastric, And Renal Cancer, Ana Carolina Rodrigues, Erika Pereira Zambalde, Daniel De Lima Bellan, Edvaldo Da Silva Trindade, Enilze Maria De Souza Fonseca Ribeiro, Daniela Fiori Gradia

Faculty, Staff and Student Publications

Lnc-uc.147, a long non-coding RNA derived from a transcribed ultraconserved region (T-UCR), was previously evidenced in breast cancer. However, the role of this region in other tumor types was not previously investigated. The present study aimed to investigate lnc-uc.147 in different types of cancer, as well as to suggest lnc-uc.147 functional and regulation aspects. From solid tumor datasets analysis of The Cancer Genome Atlas (TCGA), deregulated lnc-uc.147 expression was associated with the histologic grade of hepatocellular carcinoma, and with the tumor stage of clear cell renal and gastric adenocarcinoma. Considering the epidemiologic relevance of liver cancer, silencing lnc-uc.147 reduced the …

Gene Expression Profiling Of Circulating Tumor Cells Captured By Microcavity Array Is Superior To Enumeration In Demonstrating Therapy Response In Patients With Newly Diagnosed Advanced And Locally Advanced Non-Small Cell Lung Cancer, Evan N Cohen, Gitanjali Jayachandran, Hui Gao, Phillip Peabody, Heather B Mcbride, Pablo Lopez Bravo, Suyu Liu, Luyang Yao, Steven H Lin, James M Reuben

Faculty, Staff and Student Publications

Background: Circulating tumor cells (CTCs) are a promising non-invasive tool for monitoring therapy response. The only Food and Drug Administration (FDA)-approved test is limited to enumeration of epithelial CTC without further characterization and is not approved for the management of non-small cell lung cancer (NSCLC). Here we use a MicroCavity Array (MCA) system to capture CTC agnostic of epithelial markers for further molecular testing in NSCLC.

Methods: CTCs were enumerated by fluorescent microscopy as longitudinal sampling throughout disease management from 213 NSCLC patients. CTC-enriched samples from a subset of 127 patients were interrogated for gene expression by reverse transcription polymerase …

Association Between Covid-19 And Postoperative Neurological Complications And Antipsychotic Medication Use After Cancer Surgery: A Retrospective Study, Juan P Cata, Jian Hu, Lei Feng, Caroline Chung, Scott E Woodman

Faculty, Staff and Student Publications

Introduction: Millions of Americans infected with the severe acute respiratory syndrome-associated coronavirus-19 (COVID-19) need oncologic surgery. Patients with acute or resolved COVID-19 illness complain of neuropsychiatric symptoms. How surgery affects postoperative neuropsychiatric outcomes such as delirium is unknown. We hypothesize that patients with a history of COVID-19 could have an exaggerated risk of developing postoperative delirium after undergoing major elective oncologic surgery.

Methods: We conducted a retrospective study to determine the association between COVID-19 status and antipsychotic drugs during postsurgical hospitalization as a surrogate of delirium. Secondary outcomes included 30 days of postoperative complications, length of stay, and mortality. Patients …

Screening Spring Wheat Genotypes For Tadreb-B1 And Fehw3 Genes Under Severe Drought Stress At The Germination Stage Using Kasp Technology, Elsayed A. Mohamed, Asmaa A. M. Ahmed, Matías Schierenbeck, Mohamed Y. Hussein, P. Stephen Baenziger, Andreas Börner, Ahmed Sallam

Department of Agronomy and Horticulture: Faculty Publications

Drought stress is a major yield-limiting factor throughout the world in wheat (Triticum aestivum L.), causing losses of up to 80% of the total yield. The identification of factors affecting drought stress tolerance in the seedling stage is especially important to increase adaptation and accelerate the grain yield potential. In the current study, 41 spring wheat genotypes were tested for their tolerance to drought at the germination stage under two different polyethylene glycol concentrations (PEG) of 25% and 30%. For this purpose, twenty seedlings from each genotype were evaluated in triplicate with a randomized complete block design (RCBD) in …

Effects Of A Race Timer On The 3-Minute All-Out Test For Critical Power, Paul Mandell, Boe Burrus, Taylor Bloedon

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 4: Issue 1, Article 2, 2023. The 3-min all-out cycling test (3MT) elicits valuable fitness metrics including V̇O_2peak, HR_max, Critical Power (CP), and Work Above End Power (WEP; equivalent to work prime; W’). Twelve (n = 12) healthy active males were recruited to participate in the current study on the effects of the implementation of a race timer on the 3MT. Participants completed a V̇O_2peak test and one 3MT familiarization trial before completing one standard 3MT and one 3MT with the presence of a countdown race timer in …

A Brief Overview Of Triple A Syndrome, Jamaal Khan

Mako: NSU Undergraduate Student Journal

Triple A Syndrome, also known as AAA Syndrome, is a rare autosomal recessive disorder caused by any mutation in the AAAS gene on chromosome 12q13, whose main function is to code for the WD-repeat family regulatory protein, ALADIN. It typically occurs as a group of diseases that are characterized by alacrima, Addison's disease, and achalasia. Alacrima can be defined by a decrease in the amount of tears produced while achalasia is nerve damage in the esophagus that can cause difficulty swallowing. Lastly, Addison's disease is the insufficient production of cortisol and aldosterone produced by the adrenal cortex. There is no …

Evidence Of An Established Population Of Cherax Quadricarinatus (Von Martens, 1868) In South Texas, Usa, Adam Sanjar, Drew R. Davis, Richard J. Kline

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

Cherax quadricarinatus (von Martens, 1868) is a large parastacid crayfish (Decapoda: Parastacidae) native to Australia and Papua New Guinea. Due to various factors, C. quadricarinatus is an emerging invasive species in an increasing number of regions across the world. Deleterious ecological effects of C. quadricarinatus introduction have been documented in many of these regions, and its spread has been monitored and restricted where possible. Previously, only a small, isolated population of C. quadricarinatus in southern California had been reported within the continental United States. Here, we report the collection of three adult C. quadricarinatus from Brownsville, Cameron County, Texas, the …

Smokejumper Obituary: Tucker, William Dinwiddie “Bill” (Missoula 1950), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.

Loss-Of-Function KCa2.2 Mutations Abolish Channel Activity, Young-Woo Nam, Mohammad Asikur Rahman, Grace Yang, Razan Orfali, Meng Cui, Miao Zhang

Pharmacy Faculty Articles and Research

Small-conductance Ca²⁺-activated potassium channels subtype 2 (K_Ca2.2, also called SK2) are operated exclusively by a Ca²⁺-calmodulin gating mechanism. Heterozygous genetic mutations of K_Ca2.2 channels have been associated with autosomal dominant neurodevelopmental disorders including cerebellar ataxia and tremor in humans and rodents. Taking advantage of these pathogenic mutations, we performed structure-function studies of the rat K_Ca2.2 channel. No measurable current was detected from HEK293 cells heterologously expressing these pathogenic K_Ca2.2 mutants. When co-expressed with the K_Ca2.2_WT channel, mutations of the pore-lining amino acid residues (I360M, Y362C, G363S …

Myelin Lipid Metabolism And Its Role In Myelination And Myelin Maintenance, Joseph A Barnes-Vélez, Fatma Betul Aksoy Yasar, Jian Hu

Faculty, Staff and Student Publications

Myelin is a specialized cell membrane indispensable for rapid nerve conduction. The high abundance of membrane lipids is one of myelin's salient features that contribute to its unique role as an insulator that electrically isolates nerve fibers across their myelinated surface. The most abundant lipids in myelin include cholesterol, glycosphingolipids, and plasmalogens, each playing critical roles in myelin development as well as function. This review serves to summarize the role of lipid metabolism in myelination and myelin maintenance, as well as the molecular determinants of myelin lipid homeostasis, with an emphasis on findings from genetic models. In addition, the implications …

Extradural Primary Malignant Spinal Tumors In A Population Younger Than 25 Years: An Ambispective International Multicenter Study On Onco-Surgical Outcomes, Alexander C Disch, Stefano Boriani, Alessandro Luzzati, Laurence D Rhines, Charles G Fisher, Ziya L Gokaslan, Michelle J Clarke, Michael G Fehlings, Klaus-Dieter Schaser, Nicole M Germscheid, Jeremy J Reynolds, The Ao Spine Knowledge Forum Tumor

Faculty, Staff and Student Publications

Extradural malignant primary spinal tumors are rare and outcome data, especially for younger patients, is limited. In a worldwide (11 centers) study (Predictors of Mortality and Morbidity in the Surgical Management of Primary Tumors of the Spine study; ClinicalTrials.gov Identifier NCT01643174) by the AO Spine Knowledge Forum Tumor, patients surgically treated for primary tumors of the spine between 1992 and 2012, were retrospectively analyzed from a prospective database of their medical history. Medical history, tumor characteristics, diagnostics, treatments, cross-sectional survival, and local recurrences were analyzed. Sixty-eight cases (32 f; 36 m), at an average age of 18.6 ± 4.7 years …