Life Sciences Commons^™

Comparing Vasopressin Receptor 1a Density In Paired Vs. Widowed Coyote Brains, Jacey Hopkin

Student Research Symposium

Arginine vasopressin (AVP) is a neuropeptide known for its key role in the formation of social bonds and acts through binding to the AVP 1a receptor (AVPR1a). Most notably, research has demonstrated that monogamous species have higher levels of AVPR1a compared to non-monogamous species. AVPR1a is typically found in brain regions facilitating individual relations, social memory, and interspecies attachment; these areas are closely associated with partner preference and monogamous behavior. In addition, it has been observed in prairie voles that levels of social neuropeptides, such as oxytocin, will decrease when pair-mates are separated for extended time periods. A majority of …

Plant Growth Promoting Rhizobacteria (Pgpr) From The Native Plant Ceanothus Velutinus Promote Growth In Tall Fescue, Ananta Devkota

Student Research Symposium

Increasing reliance on chemical fertilizers for farming is hazardous to soil health. It may alter the soil’s chemical composition with time and run, making it unfit for our crops. The rhizospheric bacteria associated with the hardy native plants could be important assets for sustainable farming and a substitute for chemical fertilizers. The Intermountain west region of the US possesses several native plant species adapted to its drier climatic condition. Among them is Ceanothus velutinus (Snowbrush), which is not only drought tolerant but also harbors nitrogen-fixing Frankia species. The study was conducted to evaluate the Plant growth-promoting rhizobacteria (PGPR) on the …

Ethical Issues With Schizophrenia Research And Treatment, Chloé Brogdon

Student Research Symposium

Schizophrenia is a complex and debilitating mental disorder that affects millions of individuals worldwide. As researchers and practitioners seek to better understand and treat this condition, it is crucial to consider the ethical implications of research and treatment approaches. This project investigated the nature and scope of schizophrenia as an illness in order to delve into ethical issues with current research and treatment approaches. Ethical issues identified and analyzed include issues with informed consent, stigmatization, and access to treatment.

Netosis In Naked Mole-Rats: A Step Towards Cancer Resistance, Thomas Smith

Student Research Symposium

The purpose of this project is to identify and characterize neutrophil extracellular traps (NETs) in Naked Mole Rats (NMRs) as a step towards understanding their remarkable cancer resistance. The vision is that in doing so we can translate this understanding to human cancer research in ways that could eventually open new clinical treatment methods. Naked mole-rats are incredibly cancer resistant, and yet they possess immune cell ratios more similar to humans than to mice. Neutrophils are the most abundant immune cell in humans. They release neutrophil extracellular traps (NETs), a process referred to as NETosis, as part of an immune …

Effect Of Different Rates Of Phosphorus Application In Creeping Jenny And Periwinkle, Saroj Burlakoti

Student Research Symposium

Growing nursery plants in containers requires a timely supply of mineral nutrients for optimum growth. There is a misconception among growers that the application of higher doses of fertilizers hastens plant growth; instead, it can lead to runoff and leaching loss of nutrients. Reducing fertilizer application while sustaining healthy plants could not only negate environmental consequences but also save fertilizer costs. In this study, we wanted to determine the minimal level of phosphorus (P) application in nursery containers without significantly affecting the growth in a fast-growing ground cover i.e., Lysimachia numularia (Creeping jenny) and slow-growing ground cover i.e., Vinca minor …

Strawberry Ability To Take Up Nitrogen From Compost, Mark Kindred

Student Research Symposium

Strawberries could become a popular crop to grow in the intermountain west. To help promote this crop in organic systems, growers should know what cultivars grow the best on organic fertilizers such as compost. The main nutrient tested was nitrogen. To see how much nitrogen strawberry plants were taking up, we collected the dry weights and chlorophyll measurement at the end of the experiment. In addition, nitrogen content in the plants and in the leachate will be measured.

The Kinematics Of Motor Planning Span, Megan Sparks

Student Research Symposium

In the Sensory Motor and Behavior Lab, we are developing a new measure of motor planning span. Motor planning is defined as preparing for movement before any movement occurs. This is a critical process that allows us to do any and all physical activity. The ability to do motor planning can be impacted after a traumatic brain injury or in the case of having a neurological disorder such as Autism Spectrum Disorder. Many studies have looked at motor planning span with discrete starting and ending positions, but our study will be analyzing continuous movements. We will collect reaction time, movement …

Compound Drug Treatment Of Yellow Fever Virus: Evaluation Of Compound X In The Enhancement Of Favipiravir Potency In A Hamster Model Of Yellow Fever Virus Infection, Hunter Stanger

Student Research Symposium

Yellow fever virus (YFV) has long been a worldwide health concern, and recent outbreaks in South America have resulted in significant mortality. Though there is an effective preventative vaccine, currently there are no antiviral compounds approved to treat those already infected. The nucleoside analog drug favipiravir is shown to significantly improve disease signs but is toxic in effective doses. Compound X has been shown to have synergistic effects with favipiravir by increasing the amounts of active favipiravir (ribosylated favipiravir triphosphate) in cell culture. In this study, we administered suboptimal doses of favipiravir with fixed doses of compound X to determine …

The Role Of Extracellular Vesicles In Immunomodulation During Bovine Pregnancy, Amber Thornton

Student Research Symposium

During pregnancy, the maternal immune system must be altered to allow the tolerance of a semi-allogeneic fetus. Our previous studies show a strong inflammatory response in the uterus of cows carrying somatic cell nuclear transfer (SCNT) pregnancies due to dysregulation in the proteins expressed by trophoblast cells. Between 30 and 90 days the rate of pregnancy loss is 50-100% for SCNT compared to 2-10% for artificial insemination (AI) pregnancies. Abnormal immunological crosstalk during placentation is a major cause of this loss in SCNT pregnancies. The trafficking of extracellular vesicles (EVs), membrane-bound cargo carriers, potentially represents a key form of crosstalk …

Preliminary Maple Sap Data For Boxelder And Norway Maples, Jesse Mathews

Student Research Symposium

Maple sap is a popular agricultural product mainly produced in Quebec, Canada, and the Northeastern United States (U.S.).Almost the entire worldwide production of maple syrup exists in this area. Sugar maples (Acer saccharum) are the most popular tree to tap due to its higher sugar content. This species of maple doesn’t grow well in Utah’s soils, which might be a contributing factor to the lack of maple syrup production Utah. There exist about 211,714 boxelder (Acer negundo) trees that could be tapped in Utah. Estimates aren’t available for Norway maple (Acer platanoides) populations, but they exist in almost every park …

How Does Protein Content Of Flour Affect Sourdough Bread?, Julie Eggett, Callie Goble, Whitney Nelson

Student Research Symposium

The goal of this experiment was to evaluate if the micro-differences in protein content of bread flour made a difference in volume, air cell size, appearance, texture and flavor of sourdough bread. The flour used in this experiment included Bob’s Red Mill Artisan Bread Flour, Big J Mill Golden Loaf Bread Flour, Gold Medal Bread Flour. The protein contents were 13%, 12.7%, and 10.5%, respectively. The bread was baked using a standard recipe with only the brand of bread flour varying from sample to sample. The samples were then objectively and subjectively measured. Volume of bread samples of equal weight …

The Effect Of Different Juicing Methods On Fiber Content , Hannah Eddy, Kaylee West, Mj Wayment, Meg Chronister

Student Research Symposium

Dietary fiber is an important component in the world of nutrition. Whole fruits and vegetables are great sources that can be added to add more fiber to one's diet. Many consumers prefer to drink juice rather than add whole fruits and vegetables to their diets. However, fiber is often lost during the juicing process. The purpose of this experiment was to find the best method of juicing for a good balance of dietary fiber and flavor for each fruit or vegetable. The first independent variable was the types of fruits and vegetables being juiced: apple, pomegranate, orange, and carrot. The …

Assessing How Various Cooking Methods Influence Several Physical Qualities Of Chicken Breasts, Matthew Hulse, Jinjer Smith, Sami Allen, Melody Loutzenhiser

Student Research Symposium

Juiciness and tenderness are two of the characteristics which define meat quality and acceptability for a consumer. The purpose of this experiment is to determine the effect on moisture loss, tenderness, chewability, taste, aroma, color, and texture on chicken breast when cooked using different methods such as: sous-vide (water bath), baking, air-frying, and pan-frying. Killing harmful organisms by cooking is necessary for meat, and these different methods result in different moisture retention and texture of the product. The intention of this experiment is to equip consumers with the information they need to choose which cooking method best aligns with their …

All Purpose Flour Alternatives In Brownies, Georgia Johnson, Mckayl Black, Jouri Lacome

Student Research Symposium

Brownies are a very popular dessert. Many people are not able to tolerate the gluten in their diets, while some people may just want to add different flours. You can get other nutritional benefits from switching the flour from the all purpose flour. The alternatives in our experiment, or independent variables, were oat flour, rice flour, and banana flour. Each flour was used to bake a batch of brownies. After the brownies were finished, twelve people participated in a blind taste test. These participants subjectively tested the appearance, texture, and taste. Overall, all-purpose flour was the most desirable among participants. …

Effects Of Folding On Laminated Dough, Shelby Thorpe, Sarah Moore, Heather Burr, Colton Coombs

Student Research Symposium

The purpose of this experiment is to determine the effect on volume, flakiness, and air cell size and amount in basic croissants when the dough is folded less than and more than what’s currently considered standard. The process of dough lamination, or the creation of alternating layers of dough and fat, is a technique used in various pastries. The layer of fat, often butter or margarine, creates an impenetrable barrier to the steam, or water vapor, produced by surrounding dough layers. This facilitates lift within the pastry and while many types don’t contain yeast, lamination becomes crucial to the finalized …

A Comparison Of Candidate Banker Plants For Management Of Pests In Lettuce, Brian N. Hogg, Erik H. Nelson, Kent M. Daane

Natural Sciences and Mathematics | Faculty Scholarship

Agricultural systems are often lacking in resources for natural enemies. Providing alternative prey can help natural enemies persist through periods of low pest abundance, although this approach has been rarely commercially implemented in open field crops. In this study, we tested the potential of eight plant species to provide alternative prey to natural enemies in lettuce fields over a 2-yr period. Results showed that the tested plants would not act as sources of the lettuce aphid Nasonovia ribisnigri Mosley (Hemiptera: Aphididae), the primary lettuce pest. Of the banker plants tested, barley contained high numbers of non-lettuce aphids and appeared to …

The Impacts Of Road Salt On Water Quality And Phosphorus Dynamics In An Urban Lake, Ellen Foley

Masters Theses

Road salt runoff from de-icing applications has notably increased chloride concentrations in lakes throughout north temperate regions of the planet, with negative impacts on freshwater ecosystems. For the past 20 months, I have monitored the water quality of a chloride-impaired lake and associated tributary in Grand Rapids, Michigan. Chloride levels in the deepest part of the lake have reached up to 331 mg/L, above EPA chronic toxicity thresholds. The salt-induced density gradient has prevented the lake from completely mixing during my study period and created persistent hypoxia in the hypolimnion. Total phosphorus (TP) concentrations in the hypolimnion can exceed 7500 …

Deficit Irrigation Management For Irrigated Corn In Nebraska: Economically Viable?, Lia Nogueira, Cory Walters, Emily O'Donnell, E. Wesley F. Peterson, Suat Irmak

Cornhusker Economics

In this study we determine the economic value of deficit irrigation management using both technological and methodological advancements. The use of soil moisture probes represents the technological improvement. We provide improvements in the methodology as follows. Regarding data, we employ a field-size study, instead of plots, where the irrigation decision is determined by the moisture level in the soil measured through a soil moisture probe. Regarding the understanding of the yield response to water, although we examine the commonly used quadratic function, we improve upon this specification by also examining an alternative response function, the linear response stochastic plateau. Our …

Benthic Beasts: The Ecological Significance Of Lake Sturgeon And Blue Catfish In Eastern Appalachian Waterways, Stewart Thacker

Research Day

East Tennessee freshwater ecosystems comprise an abundance of an extremely diverse selection of species. This presentation examines Acipenser fulvescens and Ictalurus furcatus, two of the largest freshwater fish in the Appalachian area, which play significant ecological roles within the benthic dimension of our freshwater environments. Commonly known as “bottom-feeders,” Benthivorous species enjoy a broad range of food sources including other fish, detritus, crustaceans, and more. The extensive variety of food consumed by A. fulvescens and I. furcatus permits population control of other, denser, aquatic populations inhabiting other regions of the water column, as well as other organisms included …

Peer-Supervision Of Nursing Professionals: A Shield Against Burnout, Kyle Gamache, Sarah Gamache, Joseph Robillard

Journal of Wellness

Introduction: Burnout is a major risk in healthcare professions and is a significant contributor to the current nursing shortage. Strategies to combat burnout of healthcare professionals are in desperate need. The purpose of this project is to introduce the clinical peer supervision model as a method to alleviate burnout in nursing professionals.

Approach: Eight nurses from in-patient settings participated in a peer-supervision support group, modeled after existing European nursing and mental health provider-support protocols. To assess the effect of this intervention, qualitative data analysis was conducted on the transcripts of session and the results described. All participants reported statistically high …

Plants Lack The Functional Neurotransmitters And Signaling Pathways Required For Sentience In Animals, David G. Robinson, Michael R. Blatt, Andreas Draguhn, Lincoln Taiz, Jon Mallatt

Animal Sentience

We cannot agree with Segundo-Ortin and Calvo that plants are sentient organisms. We have critically examined several aspects of their target article, and find their claims are not supported by the published evidence. We address these claims in sections on whether plants have a ‘neurobiology’ analogous to that of animal nervous systems, including neurotransmitters and synaptic receptors that respond to anesthetics; and whether plant signaling resembles neural transmission. For the latter, we especially consider the unique way plants signal their responses to wounding. Although the plant vascular system has been compared to the animal nervous system, animal blood vessels would …

Development Of A Corticosteroid-Immunosuppressed Mouse Model To Study The Pathogenesis And Therapy Of Influenza-Associated Pulmonary Aspergillosis, Sebastian Wurster, Jezreel Pantaleón García, Nathaniel D Albert, Ying Jiang, Keerthi Bhoda, Yongxing Wang, Scott Evans, Dimitrios P Kontoyiannis

Faculty, Staff and Student Publications

Influenza-associated pulmonary aspergillosis (IAPA) is a feared complication in patients with influenza tracheobronchitis, especially those receiving corticosteroids. Herein, we established a novel IAPA mouse model with low-inoculum Aspergillus infection and compared outcomes in mice with and without cortisone acetate (CA) immunosuppression. CA was an independent predictor of increased morbidity/mortality in mice with IAPA. Early antifungal treatment with liposomal amphotericin B was pivotal to improve IAPA outcomes in CA-immunosuppressed mice, even after prior antiviral therapy with oseltamivir. In summary, our model recapitulates key clinical features of IAPA and provides a robust preclinical platform to study the pathogenesis and treatment of IAPA.

Physiological Measurements Pre/Post Ultra-Marathon Distance Race, Karolina Zavisiute, Scott Richmond, Chad Kerksick, Kyle Sunderland, Petey Mumford

2023 Student Academic Showcase

Endurance running events like 100 miles distance races are becoming more popular. Humans are eager to explore their limits by challenging themselves to run 100 miles distance races. However, there are many research gaps still exist to fully understand the impact on the body that 100 miles endurance event has.

The aim of this study was to measure and analyze the impact of the 100 miles endurance race among recreational runners. Ten male recreational runners (age 36.6 ± 14.1) were screened before and after completing 100 miles distance running event in Missouri. Test screening included VO2 max, RMR, BIA, Ultrasound …

Changes In Hamstring Muscle Thickness And Pennation Angle Following Nordic Exercise In A Post-Surgical Acl Patient: A Case Study, Aaliyah M. Moore, Petey W. Mumford

2023 Student Academic Showcase

This study aims to utilize ultrasound imaging to investigate the effects of Nordic hamstring exercise on a post-surgical ACL rugby patient who had a hamstring tear in the contralateral leg of his ACL tear. The study will also examine any changes in the patient's ACL leg hamstring compared to the torn hamstring leg. The patient's Biodex test results will also be incorporated to determine if there is a correlation between muscle thickness and pennation angle changes. Ultrasound scans were taken 2 months, 4 months and will be taken again at 6 months post-surgery, following biodex assessments. Ultrasound images have shown …

Female Swimmers Exhibit Greater Isometric Force Symmetry Across The Shoulder Girdle Than Male Swimmers, Lyssa Wood, Kyle Sunderland

2023 Student Academic Showcase

The Athletic Shoulder (ASH) test was developed to measure force across the shoulder girdle. This test can be used to assess symmetry and potential injury risk in upper-body sports. The purpose was to determine the differences in the supine-to-prone ratio of isometric shoulder force production between male and female swimmers. Forty-five Lindenwood swimmers (F=23, M=22) participated in this cross-sectional study. Athletes performed bilateral isometric shoulder contractions in both the supine and the prone laying position with arms straight and shoulders abducted 135˚ (“Y”). Female simmers had an higher average ratio (76.5%±13.5%) compared to males (68.1%±11.2%) independent of the arm tested. …

Peak Torque Ratios Of Hamstrings To Quadriceps Do Not Differ Between Positions Or Angular Velocities In Female Collegiate Rugby Athletes, Amanda Ware, Ava L. Denner, Kyle Sunderland

2023 Student Academic Showcase

The relative strength of hamstrings to quadriceps (H:Q) is an important measure for determining anterior cruciate ligament (ACL) injury risk, which is more prevalent in female athletes. The purpose was to examine H:Q at varying angular velocities in different position of female college rugby athletes. The dominant leg of forty-seven female college rugby athletes was evaluated via isokinetic dynamometry at 60 deg/s, 180 deg/s, 240 deg/s, and 300 deg/s. Concentric peak torques were utilized to determine H:Q. H:Q was not significantly different between positions. Additionally, there were no significant changes in H:Q at different angular velocities independent of position. These …

Hamstrings To Quadriceps Peak Torque Ratios Are Similar Between Positions In Male College Rugby Athletes, Ava Denner, Amanda Ware, Kyle Sunderland

2023 Student Academic Showcase

Decreased hamstrings strength relative to quadriceps strength (H:Q) is a potential risk factor for anterior cruciate ligament (ACL) injuries. The purpose was to determine the H:Q at varying angular velocities in male college rugby athletes. Thirty-eight male college rugby athletes volunteered for this study. Concentric peak torques were utilized to determine H:Q in the dominant leg with isokinetic dynamometry at 60 deg/s, 180 deg/s, 240 deg/s and 300 deg/s. There was no significant difference among position groups in peak torques, regardless of speed. H:Q was significantly lower at 60 deg/s compared to all other velocities. While H:Q does beneficially increase …

Arm Isometric Force Production In Ncaa Softball Players Is Greater In The Dominant Arm Independent Of Arm Angle, Nicole Henson, Kyle Sunderland

2023 Student Academic Showcase

Arm Isometric Force Production in NCAA Softball Players is Greater in the Dominant Arm Independent of Arm Angle

N. Henson1, M. Gersch1, K. Sunderland1

1Exercise and Performance Nutrition Laboratory, College of Science, Technology, and Health, Lindenwood University, St. Charles, MO, USA

The Athletic Shoulder (ASH) test is used to examine strength symmetry between dominant and non-dominant shoulders. Our purpose was to examine shoulder isometric force production in college softball players at two arm angles. Seventeen college softball players performed bilateral isometric shoulder contractions on dual force plates while laying prone with arms straight and shoulders at 135˚ (“Y”) and 180˚ …

Identifying Risk Of Acl Injury In Collegiate Male Rugby Players Across A Single Training Year, Caleb Small, Lauren Tighe

2023 Student Academic Showcase

The purpose of this study to examine collegiate male rugby players’ susceptibility for sustaining an ACL injury over the course of an entire season using the biodex strength assessment, standardized functional movement screen, and Y-balance test. Participants included five male collegiate rugby players who play in the back line ranging from age eighteen through twenty-three. Baseline testing was conducted during preseason training and re-assessed every four weeks throughout the entire season. Assessment measures remained the same throughout all testing trials, in addition to a subjective patient questionnaire. Following data collection, three out of the five participants showed deficiency of hamstring …

Multidrug-Resistant Pseudomonas Aeruginosa, Addison Haddock, Chad Welsh

2023 Student Academic Showcase

Multidrug-resistant Pseudomonas aeruginosa is a pathogenic bacterium that has developed resistance to several previously adequate treatments. This is a growing health crisis in the United States, particularly in hospitals where vulnerable individuals are at increased risk of exposure and infection. The scientists challenging this issue are investigating the processes driving the bacterium’s drug resistant nature in hopes of discovering effective treatment strategies. However, as the bacterium continues to evolve and acquire new mutations over time, it becomes increasingly difficult to combat. The emergence and persistent spread of multidrug-resistant Pseudomonas aeruginosa in healthcare settings pose a hazard to society, emphasizing the …