Life Sciences Commons^™

Ecological Impacts Of Invasive Crayfish In A Naïve Riparian System, Gregor L. Hamilton

Biology ETDs

Aquatic and riparian food webs are inextricably linked. In deserts, they provide critical energy subsidies to surrounding terrestrial food webs, but these vital subsidies are not guaranteed; streams in arid lands are especially sensitive to perturbations. In this dissertation, I investigated the role of an oft-cited threat to stream communities in the lower Colorado River basin: non-native crayfish. I contributed to methodologies in passive integrated transponder use and length-weight relationships in crayfish to aid future research. I leveraged stable isotope analysis of δ¹⁵N, δ¹³C, and δ²H to understand crayfish role in the food webs. …

The Halliwick Concept: Practical Applications, Susan J. Grosse

International Journal of Aquatic Research and Education

The Halliwick Concept has become a very popular method for use by professionals involved in instructional swimming and in therapeutic aquatics. Through a detailed look at the principles of Halliwick, this article expands on Halliwick theory by detailing applications of Halliwick to specific population groups. The practicality of implementing Halliwick methodology with and for individuals experiencing a variety of limiting challenges, both physical and cognitive/sensory, are discussed. Hints for success- oriented implementation are provided. For those unfamiliar with the Halliwick Method background resource material is included.

Freestyle: A Guide To Making Swimming Nutrition Simple, Megan Wills

Undergraduate Theses

Nutrition plays a critical role in the performance of an athlete. Although academic research surrounding the topic has increased, there is a disproportionate increase in materials created for the athletes themselves. Regarding competitive swimming, the scope of athlete-friendly instructional materials is even more limited. Therefore, there is an inherent disconnect between the academic research on the topic of competitive swimming nutrition and the athletes who need the information. The purpose of this project is to bridge the gap between the research and the content accessible for athletes themselves. Using an interpretive and simplistic approach, the available academic research was used …

Transcriptional Silencing Of Cdk18 And Its Role In Lung Carcinogenesis Of Brg1-Mutant Lung Cancers, Loryn M. Phillips

Biology ETDs

BRG1 is mutated in 10% of lung cancers, making this mutation clinically relevant. The downstream effects of BRG1 included significantly affecting the cell cycle control and chromosomal replication pathway. CDK18, a cyclin-dependent kinase, was determined to be the gene with significantly decreased expression (p < 0.0001) in the cell cycle control and chromosomal replication pathway. CDK18 is active during the S-phase of the cell cycle and required for genomic stability. Studies were conducted to determine the epigenetic mechanisms that contributed to the repression of CDK18. Histone methylation contributes to the repression of CDK18, and histone deacetylation globally regulates expression of CDK18, while cytosine methylation was found to not contribute to CDK18 expression. Studies were performed to elucidate CDK18 functional role lung carcinogenesis and the genome-wide impact of CDK18 repression. Repression of CDK18 affects cell migration, proliferation, cell-cell signaling, and anchorage-independent growth that contribute to cancer initiation and progression.

Anthracycline-Containing And Taxane-Containing Chemotherapy For Early-Stage Operable Breast Cancer: A Patient-Level Meta-Analysis Of 100 000 Women From 86 Randomised Trials, Early Breast Cancer Trialists’ Collaborative Group (Ebctcg)

Faculty, Staff and Student Publications

BACKGROUND: Anthracycline-taxane chemotherapy for early-stage breast cancer substantially improves survival compared with no chemotherapy. However, concerns about short-term and long-term side-effects of anthracyclines have led to increased use of taxane chemotherapy without anthracycline, which could compromise efficacy. We aimed to better characterise the benefits and risks of including anthracycline, and the comparative benefits of different anthracycline-taxane regimens.

METHODS: We did an individual patient-level meta-analysis of randomised trials comparing taxane regimens with versus without anthracycline, and updated our previous meta-analysis of anthracycline regimens with versus without taxane, as well as analysing 44 trials in six related comparisons. We searched databases, including …

Nuclear Export Signal Mutation Of Epidermal Growth Factor Receptor Enhances Malignant Phenotypes Of Cancer Cells, Lei Nie, Ying-Nai Wang, Jung-Mao Hsu, Junwei Hou, Yu-Yi Chu, Li-Chuan Chan, Longfei Huo, Yongkun Wei, Rong Deng, Jun Tang, Yi-Hsin Hsu, How-Wen Ko, Seung-Oe Lim, Kebin Huang, Mei-Kuang Chen, Tai-Jan Chiu, Chien-Chia Cheng, Yueh-Fu Fang, Chia-Wei Li, Aarthi Goverdhan, Hsing-Ju Wu, Cheng-Chung Lee, Wen-Ling Wang, Jennifer Hsu, Paul Chiao, Shao-Chun Wang, Mien-Chie Hung

Faculty, Staff and Student Publications

Nuclear epidermal growth factor receptor (EGFR) has been shown to be correlated with drug resistance and a poor prognosis in patients with cancer. Previously, we have identified a tripartite nuclear localization signal (NLS) within EGFR. To comprehensively determine the functions and underlying mechanism of nuclear EGFR and its clinical implications, we aimed to explore the nuclear export signal (NES) sequence of EGFR that is responsible for interacting with the exportins. We combined in silico prediction with site-directed mutagenesis approaches and identified a putative NES motif of EGFR, which is located in amino acid residues 736-749. Mutation at leucine 747 (L747) …

Molecular Disparity Of Hla-Dpb1 Is Associated With The Development Of Subsequent Solid Cancer After Allogeneic Hematopoietic Stem Cell Transplantation, Jun Zou, Piyanuch Kongtim, Betül Oran, Samer A Srour, Uri Greenbaum, Yudith Carmazzi, Gabriela Rondon, Stefan O Ciurea, Qing Ma, Elizabeth J Shpall, Richard E Champlin, Kai Cao

Faculty, Staff and Student Publications

Background: An increased incidence of subsequent solid cancers (SSCs) has been reported in long-term survivors of allogeneic hematopoietic stem cell transplantation (allo-HSCT), and SSC is associated with inferior mortality and morbidity. Previous studies showed that the incidence of SSC is significantly higher in those who underwent allo-HSCT from HLA-mismatched donors, suggesting that persistent alloimmunity may predispose patients to SSCs. It was recently reported that, in a cohort of patients who received allo-HSCT from an unrelated donor matched at HLA-A, -B, -C, -DRB1/3/4/5, and -DQB1 loci, HLA-DPB1 alloimmunity determined by high mismatched eplets (MEs) and Predicted Indirectly Recognizable HLA Epitopes (PIRCHE) …

Volume 9 Full Text, Bjur Staff

Butler Journal of Undergraduate Research

No abstract provided.

Air Temperature And Diet Are Not Associated With Oxygen Consumption Rate In Banded Crickets, Gryllodes Sigillatus, Nicole Bailey, Connor Oakes, Rachel Sleeth, Mallorie Smith

Butler Journal of Undergraduate Research

All living organisms acclimate to their environments, with ectothermic species particularly susceptible to environmental change, specifically temperature. Ectothermic insects like crickets directly alter their physiological processes depending on the environment in which they live. Temperature is vital in regulating processes such as metabolism, respiration, and reproduction, among other things. What remains unclear is how a change in the environment, specifically extreme temperature change and dietary alterations, affects physiological processes. In this study, we performed experiments on ectothermic banded crickets to examine the effects of temperature change and the interaction of temperature and diet on oxygen consumption. For both experiments, we …

Effects Of Anthropogenic Noise On Body Mass In Gryllodes Sigillatus, Jessica L. Venturi, Joyce Zheng

Butler Journal of Undergraduate Research

Insects use vibrational structures to produce and sense airborne sounds in intraspecific communication. These signals are important in courtship as well as defensive behavior against predators. For example, insects can detect the presence of nearby predators using vibrations. With an increase in anthropogenic activity, processing these signals and the constant threat they represent may increase stress on insects, subsequently affecting their behavior and physiology. Our experiment was designed to determine whether anthropogenic noise, possibly perceived as a stressor, will decrease the body mass of banded crickets, Gryllodes sigillatus. We predicted that the anthropogenic noise would stress the crickets, leading to …

Truth, Not Accuracy: Native American Fiction Vs. White Settler Colonialism, Charles Democker

Butler Journal of Undergraduate Research

For centuries, depictions of Native American culture have largely been constructed by White authors and have thus reflected white settler colonialist ideology. This paper suggests that one way to counter this point of view when studying Native American history is to turn to fiction, specifically fiction written by Indigenous authors. Taking as an example Ojibwe author Louise Erdrich’s Plague of Doves, a novel based on the real-life massacre of a frontier family in the late nineteenth century, this paper argues that the creative fiction of Indigenous authors can counter the biased, incomplete, and often incorrect official histories of White–Native interactions. …

Higher Education Students’ Perceptions Of Online Learning During The Covid-19 Pandemic, Abby O’Bryant

Butler Journal of Undergraduate Research

This article focuses on the impacts of online learning during the COVID-19 pandemic on students at the University of Hawai‘i at Hilo. Using survey data (n = 64) and semistructured interviews with currently enrolled students (n = 17), key impacts of online learning on the student body were analyzed. The respondents reported disengagement in lectures, negative impacts on their mental and physical health, negative thoughts about dropping out and transferring, apprehension about the quality of course content, and dissatisfaction with tuition. The paper utilizes qualitative data analysis to report the findings.

Bad Boy Bias: Linguistic Bias In The Law, Parth Sharma

Butler Journal of Undergraduate Research

This paper seeks to establish and put in use methodology capable of analyzing the significant linguistic bias found within American jurisprudence. It summarizes the limited preexisting empirical work done and adds a new original empirical study on linguistic bias in the courtroom. It examines a large number of cases through various software and examines the prevalence of certain labels (badges of bias). In doing so, this paper seeks to find the most common labels and seeks to determine the amount of emotional variability present within the courtroom. Based on these results, the paper provides recommendations, answering how best to efficiently …

Survival Of Deaf Jewish People During The Holocaust Era, Phyllis D. Rifkin

Butler Journal of Undergraduate Research

This project uses academic and personal research to explore the experiences of Deaf Jewish survivors of the Holocaust. The author is a member of the Deaf community and a Deaf Interpreter, as well as the daughter of a Deaf Jewish Holocaust survivor. She examines the construction of Deafness in the eugenics era and chronicles the stories of Deaf Jewish survivors. A recurring theme in these narratives is Deaf survivors’ strategic use of silence to facilitate survival.

The Physics Research Problem: A Brief Analysis Of Financial And Administrative Factors Relating To Recent Trends In Research Output In Physics In India, Varad Dhodapkar

Butler Journal of Undergraduate Research

This paper attempts to view and interpret data from various sources such as the World Bank database, research and development (R&D) reports by the Indian government, Nature Index, Scopus index, and others to examine the effect that the various government financial initiatives and administrative features and policies concerning funding of institutions of higher attainment have had on India’s research output in the field of physics. In addition to this, the inconsistent standards of funding across various institutes of higher education, investment in R&D activities made by other nations in comparison to India, the share of physics research output of various …

Almost 30 Years Later: Anti-Femicide Activism In Mexico From 1993 To 2022, Kathryn Webb

Butler Journal of Undergraduate Research

What factors have influenced the strategies of the anti-femicide social movement, and what has this movement accomplished after continuously advocating for almost 30 years? Analyzing news articles, scholarly journals, books on social movements, and Twitter accounts, I argue that the inaction of the government was a root cause of the movement’s change in strategies, from peaceful petitions to highly visible vandalism, and that institutional barriers prevent progress on this issue even in the current day. I demonstrate that transnational activism through international institutions such as the United Nations had a limited impact on effecting domestic change but that using social …

Work-Life And Health Experiences Of Computer Science Faculty Parents Of Children With Developmental Disabilities During Covid-19, Molly Armstrong

Butler Journal of Undergraduate Research

Prior to the COVID-19 pandemic, parents of children with developmental disabilities (PCDD) had been shown to experience more stress than parents of children without developmental disabilities (non-PCDD). COVID-19 may have exacerbated difficulties for PCDD. To compare differences in COVID-19 experiences between PCDD and non-PCDD, 202 parents working as computer science (CS) faculty reported their experiences of mental health symptoms, physical health symptoms, work-life conflict levels as experienced during the pandemic, and any changes in their childcare responsibilities because of COVID-19. Participants completed surveys on their experiences during Fall 2020 and Spring 2021, the first academic year after the start of …

Agency Actualization And Artistic Awakening: The Poetic Rhetoric Of Freedom School Students, Eden Doyle

Butler Journal of Undergraduate Research

This paper analyzes the rhetoric of poems written by Freedom School students in Mississippi amidst the Civil Rights Movement of the 1960s. Much of the rhetoric documented, explored, and valued from this era is of adults with the power and means to have their voices heard and respected; however, this paper argues the value of these students’ unique Black experience as one that is underexplored and greatly compelling. The social and political context surrounding the inception of Freedom Schools is discussed, as well as the need for further research and scholarship on the intellectual activity and rhetorical artifacts of the …

The Effects Of Covid-19-Induced Stress, Anxiety, And Depression On The Eating Behavior Of College Women, Natalie Simpson

Butler Journal of Undergraduate Research

Increases in the prevalence of disordered eating patterns have been linked to distress and poor mental well-being. Additionally, COVID-19 has been linked to both depressive and anxious symptomatology, along with increased feelings of distress (Fitzpatrick et al., 2020). Because disordered eating is particularly prevalent among college-age women, this study sought to determine how depression, anxiety, and stress affect eating behaviors of college women in the context of the COVID-19 pandemic. One hundred seventy-nine women, aged 18–24, at Butler University gave informed consent before completing a questionnaire pertaining to their demographics, their stress surrounding COVID, and their weight change since March …

An Evaluation Of Women’S Social Status In Colonial Hong Kong With A Feminist Lens - Case Studies, Heng Du

Butler Journal of Undergraduate Research

Even though Hong Kong remained under British control from 1842 to 1997, denizens were not modernized in a way comparable to that of the British. To the contrary, while governing Hong Kong, British colonizers allowed continued reference to ancient Chinese customs in the area. Such policy diminished women’s chances of receiving fair treatment in matters such as property management and divorce. Unlike in Hong Kong, women were legislated to be parallel to men in matrimonial and property inheritance petitions in China, Britain, and colonial Singapore. This study is based on two exemplary cases judged by authorities in colonial Hong Kong. …

The Effect Of Covid-19 On Substance Use And Mental Health On A College Campus, Georgia L. Coffman

Butler Journal of Undergraduate Research

In this research, the author surveyed a university population to determine the impact that COVID-19 has had on substance use and mental health. Current research provides significant data indicating worsening mental health and substance use. This paper looks at how applicable those trends are to a small private university in Indianapolis, Indiana. The data included 261 respondents composed of students, faculty, and staff of the university. The results reveal that college students, faculty, and staff experienced statistically significant increases in feelings of unhappiness, depression, loneliness, hopelessness, agitation, and irritability during the pandemic compared to before the pandemic. Data analysis of …

Identifying Disinformation In Scholarly Publishing, Natalie M. Mclendon

Butler Journal of Undergraduate Research

This paper examines the pro-Confederacy movement’s attempt to distort history through textbook revision to argue in favor of strengthened media literacy as a brace against the effects of disinformation and propaganda. Previous definitions of misinformation and disinformation overlap and are as yet unclear and, therefore, should be further studied. “Lost Cause” mythologists worked diligently to propagate school textbooks which portrayed skewed versions of history that cast Southern Confederates’ cause as noble and honorable while obscuring the real reason for the Civil War. While undergraduate students can rely on the CRAAP and BEAM methods of identifying problematic texts, they should be …

Table Of Contents And Front Matter, Bjur Staff

Butler Journal of Undergraduate Research

No abstract provided.

Darwin Core Archive File, Stover-Ebinger Herbarium, Eastern Illinois University

Darwin Core Archive Download

ZIP file contains occurrences.csv, identivications.csv, and images.csv. The meta.xml document describes the content. Fields within the occurrences.csv file are defined by the Darwin Core exchange standard.

This file is updated as new occurrence records are added.

Water Erosion In The South-West Of Western Australia, Department Of Primary Industries And Regional Development, Western Australia

Natural resources factsheets

The averaged annual direct cost of water erosion to dryland farming in Western Australia is estimated to be $10 million, but the costs are much higher in years of severe summer storms.

Water erosion occurs when water flowing over the land surface moves soil particles downslope. Water erosion is a natural process, but is accelerated under agriculture, especially on cropped land. Water erosion causes loss of topsoil, reduced crop yields, damaged infrastructure, weed dispersal, eutrophication (algal blooms) and silting of dams and natural waterways.

Characterization Of Select Lysine Mutations Of The Cystine/Glutamate Transporter, System XC-, Anna Koppin, Claire Buck, Amanda Gibson

22nd Annual Celebration of Undergraduate Research and Creative Activity (2023)

System xc- is a membrane transport system that plays a critical role in mitigating oxidative stress. As such, its regulation is critical for proper brain functioning. Recent work in our lab has shown that System xc- activity increases immediately during an oxidative insult by undergoing a change in localization to the plasma membrane, but we have yet to identify the specific mechanism for the redistribution of the transporter. Previous studies have demonstrated that post-translational modifications of proteins can lead to differential protein distribution within cells. Therefore, in this study, we sought to determine if post-translational modification (PTM) of the transporter …

Development Of A Novel Method For Identifying Antibiotic Producing Microbes From The Soil, Sean Slayton

22nd Annual Celebration of Undergraduate Research and Creative Activity (2023)

Multi-drug resistant (MDR) bacteria are strains of bacteria that are resistant to multiple types of antibiotics and pose a serious public health threat. Our research group has developed a novel way to rapidly screen soil bacteria isolates for antimicrobial chemical production in a clear and reproducible manner. We examined the effects of certain variables on our method including: 1) agar type on antimicrobial diffusion, 2) agar depth on antimicrobial diffusion, 3) age of the soil isolate on the amount of antimicrobial produced, and 4) soil isolate placement on the inhibition of bacterial growth. Our combined results led to the creation …

Effect Of Post-Warm-Up Transition Time On Anaerobic Performance In Female Collegiate Volleyball Players, Samantha Martino, Sophia Rosiek, Haleigh Cripe

22nd Annual Celebration of Undergraduate Research and Creative Activity (2023)

Post-warm-up transition time (PWTT) is the period of time between the end of a pre-game warm-up and the beginning of gameplay at a particular sporting event. During this period of time, typical pregame traditions are completed such as the playing of the National Anthem and recognition of players and coaches. This length of time can vary from sport to sport. Research shows that a dynamic warmup is encouraged to improve performance and decrease the risk of injury. Further, rest periods are necessary for optimal performance. Too short of a recovery time can result in muscle tissue damage, but too long …

Role Of Neuroinflammatory Response On Cell Proliferation Following Neurotoxic Lesioning In Zebrafish, Sarah Heinowski, Nathaniel Vorhees, Nathan Koorndyk, Helen Dodge

22nd Annual Celebration of Undergraduate Research and Creative Activity (2023)

Parkinson's Disease (PD), a neurodegenerative disorder characterized by dopaminergic neuronal loss and motor impairment, affects roughly 1 in 500 people. Interestingly, olfaction loss, the loss of smell, is prevalent in over 95% of those with PD. Zebrafish provide a unique model to study neurodegenerative diseases, including PD, as they possess the unique ability to regenerate neurons (i.e., neurogenesis) throughout their lifespan. Contrary to mammals in which inflammation often has negative associations with neural injury recovery, inflammatory response within zebrafish is thought to have a key role in this regenerative capability. Thus, we aimed to inhibit the inflammatory response and investigate …

Temporal Analysis Of Former High School Athletes’ Perceptions Of Fitness As They Enter College, Alec W. Kowalski, Sophia K. Rosiek, Adam H. Ibrahim

22nd Annual Celebration of Undergraduate Research and Creative Activity (2023)

Researchers suggest that physical activity promotion may be necessary to preserve former athletes' long-term health and transition out of sport in retirement. Exploratory research has revealed that the fitness perceptions (a known contributor to exercise behavior) of former high school athletes (FHSAs) who do not continue sports in college fluctuate over the course of their freshman year. To inform potential intervention efforts in this population, the purpose of this study was to explore why FHSAs' perceptions of fitness vary over their freshman year of college. Methods: Participants completed eight online surveys over their first year of college, within which they …