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Articles 37321 - 37350 of 256002
Full-Text Articles in Life Sciences
The Academic Training In Media Faculties And Its Implications For Professional Practice: A Field Study On Media Practitioners In Jordanian Media Institutions, Ramez Abuhasirah
The Academic Training In Media Faculties And Its Implications For Professional Practice: A Field Study On Media Practitioners In Jordanian Media Institutions, Ramez Abuhasirah
This study aimed at identifying the reflection of media academic education on professional practice. The study adopted the audience survey method. A questionnaire was distributed to an available sample of (102) professionals in Jordanian media institutions who hold a media certificate. The study’s results showed that the primary academic education of media professionals was represented in: “the predominance of theoretical aspects over practical aspects in academic courses,” with a mean of (4.30). In contrast, the media skills and practical professional training of professionals in Jordan’s media institutions were represented in: “the reflection of media training on the professional performance of …
The Phenomenon Of Information Flow From Traditional And New Media About The Corona Pandemic From The Perspective Of Newly Graduated Media Professionals In Yemen, Mansour Al-Muntasir
The Phenomenon Of Information Flow From Traditional And New Media About The Corona Pandemic From The Perspective Of Newly Graduated Media Professionals In Yemen, Mansour Al-Muntasir
This study aims to explore the external limits of the Corona pandemic in all traditional and new media, which paid attention to this event in a way that the media had not seen before, relying on citizens' participation in the production of news in social media. This study also aims to find out how newly graduated journalists interact with the event on both professional and personal levels, especially with the spread of misinformation and fake news about the Corona virus. The researchers have adopted the qualitative method to obtain deep information from the sample selected by the study, as it …
The Role Of Radio And Television Programmes In Providing Drug Information From The Perspectives Of The Jordanian Public And Pharmaceutical Sector Employees, Obadah Sa’Ad, Omar Al Rashdan, Hanan Al-Shiekh
The Role Of Radio And Television Programmes In Providing Drug Information From The Perspectives Of The Jordanian Public And Pharmaceutical Sector Employees, Obadah Sa’Ad, Omar Al Rashdan, Hanan Al-Shiekh
This study aimed to identify the role of radio and television programmes in providing drug information to the Jordanian society. The study adopted the descriptive analytical approach, and two special questionnaires were developed for the study. The study sample consisted of (287) employees from the pharmaceutical sector (pharmacists, doctors), and (389) members of the Jordanian public who visited Hamzah and Al-Bashir Hospitals in Amman, Jordan. The results of the study concluded that the role of radio and television programmes in providing drug information to the Jordanian society from the viewpoint of the public came to a medium degree, and that …
The Reality Of Media Training In Jordanian Media Institutions From The View Point Of Journalists - A Field Study, Kamel Khurshid Murad, Saddam Al-Mashagbah
The Reality Of Media Training In Jordanian Media Institutions From The View Point Of Journalists - A Field Study, Kamel Khurshid Murad, Saddam Al-Mashagbah
The article aimed to identify the reality of media training in Jordanian media institutions from the point of view of journalists in Jordan. It adopted a descriptive approach using a questionnaire distributed to a simple random sample of (66) journalists in the Radio and Television Corporation, Petra Agency, daily newspapers, some electronic news websites, the Journalists Syndicate and some satellite channels. The results revealed that 43.9% of the media institutions have departments for training, and 51.5% are interested in holding training courses at a medium rate. The results also showed that 53.0% of the sample describe the percentage of learning …
The Impact Of Negative Online Rumors On The Attitudes Of The Palestinian Audience Towards The Liberation Of The Six Prisoners: A Content Analysis Of Facebook Pages, Suhair Al Rjoub, Saed Shaheen
The Impact Of Negative Online Rumors On The Attitudes Of The Palestinian Audience Towards The Liberation Of The Six Prisoners: A Content Analysis Of Facebook Pages, Suhair Al Rjoub, Saed Shaheen
This research aims to identify the topics covered by Facebook pages regarding the issue of the six prisoners’ liberation. It deals with the negative impact of rumors on the Palestinian public’s attitudes towards the issue of the six prisoners’ liberation on Facebook through analyzing the content of the pages. In this study, the research used the content analysis tool; the sample of the study included five pages that dealt with the issue of the six prisoners who liberated themselves through a tunnel under Gilboa prison. The research deployed the theory of social responsibility and relied on the “descriptive survey” to …
The Effectiveness Of Media Curricula In Sudanese Universities In Light Of The Challenges And Requirements Of The Labor Market In The Era Of Digital Media From Media Faculties’ Perspectives, Lamia Salah Al Deen Mohammad Ibrahim
The Effectiveness Of Media Curricula In Sudanese Universities In Light Of The Challenges And Requirements Of The Labor Market In The Era Of Digital Media From Media Faculties’ Perspectives, Lamia Salah Al Deen Mohammad Ibrahim
This study aimed to identify the effectiveness of the media curricula in Sudanese universities regarding the challenges and the requirements of the labor market in the era of digital media. The researcher used the descriptive analytical approach; an electronic questionnaire form was designed as a tool for data collection. It was distributed to a simple random sample consisting of (40) individuals, representing (45%) of the total study population represented by (95) professors. The study concludes with a number of findings, most importantly are: the degree of effectiveness of the media curricula in Sudanese universities in light of the challenges and …
The Effectiveness Of Interactive Video In Developing Animation Production Skills For Educational Technology Students At Middle East University, Fadi Abdulraheem Odah
The Effectiveness Of Interactive Video In Developing Animation Production Skills For Educational Technology Students At Middle East University, Fadi Abdulraheem Odah
This study deals with the effectiveness of interactive video in developing animation production skills among Educational Technology students at Middle East University. The researcher used semi-experimental mothod, where the research sample consisted of (40) students from Educational Technology students at the Faculty of Educational Siences, Middle East University. The sample consisted of two equal groups: a control group of (20) male and female students that were taught in the usual way at laboratories, and an experemental group of (20) students that were taught through interactive vide. The research tools consisted of an observation card to measure the performance. The results …
The Who’S Interest In Its Communication Messages On (Covid-19) Pandemic Via Facebook And Twitter Platforms, Rana Mezher Khalid, Layla Ahmad Jarrar
The Who’S Interest In Its Communication Messages On (Covid-19) Pandemic Via Facebook And Twitter Platforms, Rana Mezher Khalid, Layla Ahmad Jarrar
The study aims to identify the degree of interest of the World Health Organization (WHO) through social networks in dealing with the Covid-19 pandemic on Facebook and Twitter platforms. The theory of media frameworks was implemented, and the content analysis was used as a tool for quantitative and qualitative analysis of the communicative messages of the organization. A deliberate sample was selected, which included all the messages of the World Health Organization during the period from the beginning of the disease until its declaration as a global pandemic, that is: during the period from 30/12/2019 – 11/3/2020, and this time …
Job Satisfaction Among Female Media Professionals In Palestine And The Obstacles They Face In Practicing Their Work, Mohammad Ahmad Injas, Izzat Mohammad Hijab
Job Satisfaction Among Female Media Professionals In Palestine And The Obstacles They Face In Practicing Their Work, Mohammad Ahmad Injas, Izzat Mohammad Hijab
The study aimed to identify the climates in which Palestinian female media work, identify the obstacles that female media face, and identify their degree of job satisfaction. The study used the descriptive survey method, and the study adopted a questionnaire as a tool for collecting data related to the topic of the research, which was distributed to a random sample of (180) female media professionals out of (206) female media workers, according to the Palestine Journalists Syndicate record for the year 2020. The results of the study showed that the media profession affects the familial and family stability of female …
How The Palestinian Cause Has Been Framed In The Jordanian Opinion Articles, Hani Ahmad Fayez Al-Badri
How The Palestinian Cause Has Been Framed In The Jordanian Opinion Articles, Hani Ahmad Fayez Al-Badri
This study aims to identify the presentation of the Palestinian cause in Jordanian opinion articles published on online news sites representing daily newspapers. In addition to monitoring the topics and issues that have been highlighted, and comparing the similarities and differences between the sample newspapers in discussing this cause. The study uses the media survey methodology and the comparative approach in order to obtain required data and information, and compare the analysis results of the opinion articles in both Alghad and Addustour newspapers. The study population is represented in the opinion articles published on online news sites that represent daily …
The Role Of Jordanian Mass Media In Facing The Rumors From Communication Practitioner’S Perspective: Survey Study, Rami Basem Yousef Haddad, Kamel Khurshid Murad
The Role Of Jordanian Mass Media In Facing The Rumors From Communication Practitioner’S Perspective: Survey Study, Rami Basem Yousef Haddad, Kamel Khurshid Murad
The study aimed to define role of the Jordanian media in facing rumors as seen by communicators, to identify the most common rumors and the motives behind them. The study adopted the survey method with a questionnaire as a tool for collecting data. The study The study aimed to define role of the Jordanian media in facing rumors as seen by communicators, to identify the most common rumors and the motives behind them. The study adopted the survey method with a questionnaire as a tool for collecting data. The study population consisted of 397 communicators working in official Jordanian media …
Political Participation In Jordan In Light Of The Royal Discussion Papers, Sahar Mohammad Al Tarawneh, Rema Lutfi Abu Hmidan
Political Participation In Jordan In Light Of The Royal Discussion Papers, Sahar Mohammad Al Tarawneh, Rema Lutfi Abu Hmidan
Effective political participation plays a key role in promoting good democratic governance and the rule of law in order to achieve transparency and the principle of accountability, which contribute mainly to the process of political, economic and social development. This study aims to define political participation and its application forms, and to identify democratic practices and the elements of political participation in Jordan in light of the political reform process and the royal discussion papers. The study also tackles the role of the means of communication and media as a major factor in this process and discusses the opportunities of …
A Protein Kinase Coordinates Cycles Of Autophagy And Glutaminolysis In Invasive Hyphae Of The Fungus Magnaporthe Oryzae Within Rice Cells, Gang Li, Ziwen Gong, Nawaraj Dulal, Margarita Marroquin-Guzman, Raquel O. Rocha, Michael Richter, Richard A. Wilson
A Protein Kinase Coordinates Cycles Of Autophagy And Glutaminolysis In Invasive Hyphae Of The Fungus Magnaporthe Oryzae Within Rice Cells, Gang Li, Ziwen Gong, Nawaraj Dulal, Margarita Marroquin-Guzman, Raquel O. Rocha, Michael Richter, Richard A. Wilson
Department of Plant Pathology: Faculty Publications
The blast fungus Magnaporthe oryzae produces invasive hyphae in living rice cells during early infection, separated from the host cytoplasm by plantderived interfacial membranes. However, the mechanisms underpinning this intracellular biotrophic growth phase are poorly understood. Here, we show that the M. oryzae serine/threonine protein kinase Rim15 promotes biotrophic growth by coordinating cycles of autophagy and glutaminolysis in invasive hyphae. Alongside inducing autophagy, Rim15 phosphorylates NADdependent glutamate dehydrogenase, resulting in increased levels of α- ketoglutarate that reactivate target-of-rapamycin (TOR) kinase signaling, which inhibits autophagy. Deleting RIM15 attenuates invasive hyphal growth and triggers plant immunity; exogenous addition of α-ketoglutarate prevents these …
Identification Of T-Dna Structure And Insertion Site In Transgenic Crops Using Targeted Capture Sequencing, Eric Maina Magembe, Hui Li, Ali Taheri, Suping Zhou, Marc Ghislain
Identification Of T-Dna Structure And Insertion Site In Transgenic Crops Using Targeted Capture Sequencing, Eric Maina Magembe, Hui Li, Ali Taheri, Suping Zhou, Marc Ghislain
Agricultural and Environmental Sciences Faculty Research
The commercialization of GE crops requires a rigorous safety assessment, which includes a precise DNA level characterization of inserted T-DNA. In the past, several strategies have been developed for identifying T-DNA insertion sites including, Southern blot and different PCR-based methods. However, these methods are often challenging to scale up for screening of dozens of transgenic events and for crops with complex genomes, like potato. Here, we report using target capture sequencing (TCS) to characterize the T-DNA structure and insertion sites of 34 transgenic events in potato. This T-DNA is an 18 kb fragment between left and right borders and carries …
The Impact Of Training In Financial Basics On Small Farm Producers’ Knowledge In Selected Alabama Black Belt Counties, Eunice K. Waweru
The Impact Of Training In Financial Basics On Small Farm Producers’ Knowledge In Selected Alabama Black Belt Counties, Eunice K. Waweru
College of Agriculture, Environment and Nutrition Sciences Graduate Theses and Dissertations
THE IMPACT OF TRAINING IN FINANCIAL BASICS ON SMALL FARM PRODUCERS’ KNOWLEDGE IN SELECTED ALABAMA BLACK BELT COUNTIES
By
Eunice K. Waweru
The author expresses her sincere gratitude to her major advisor, Dr. David Nii. O. Tackie. His encouragement, expertise, guidance, wisdom, patience, and unwavering support has been instrumental in shaping her thesis. His feedback and constructive criticisms have been of tremendous help and has helped her refine her ideas and improve the quality of her thesis. She is forever grateful for his mentorship and the opportunities he has provided her during her academic journey. Also, she is grateful to …
A Protein Kinase Coordinates Cycles Of Autophagy And Glutaminolysis In Invasive Hyphae Of The Fungus Magnaporthe Oryzae Within Rice Cells, Gang Li, Ziwen Gong, Nawaraj Dulal, Margarita Marroquin-Guzman, Raquel O. Rocha, Michael Richter, Richard Wilson
A Protein Kinase Coordinates Cycles Of Autophagy And Glutaminolysis In Invasive Hyphae Of The Fungus Magnaporthe Oryzae Within Rice Cells, Gang Li, Ziwen Gong, Nawaraj Dulal, Margarita Marroquin-Guzman, Raquel O. Rocha, Michael Richter, Richard Wilson
Department of Plant Pathology: Faculty Publications
The blast fungus Magnaporthe oryzae produces invasive hyphae in living rice cells during early infection, separated from the host cytoplasm by plantderived interfacial membranes. However, the mechanisms underpinning this intracellular biotrophic growth phase are poorly understood. Here, we show that the M. oryzae serine/threonine protein kinase Rim15 promotes biotrophic growth by coordinating cycles of autophagy and glutaminolysis in invasive hyphae. Alongside inducing autophagy, Rim15 phosphorylates NADdependent glutamate dehydrogenase, resulting in increased levels of α- ketoglutarate that reactivate target-of-rapamycin (TOR) kinase signaling, which inhibits autophagy. Deleting RIM15 attenuates invasive hyphal growth and triggers plant immunity; exogenous addition of α-ketoglutarate prevents these …
A Protein Kinase Coordinates Cycles Of Autophagy And Glutaminolysis In Invasive Hyphae Of The Fungus Magnaporthe Oryzae Within Rice Cells, Gang Li, Ziwen Gong, Nawaraj Dulal, Margarita Marroquin-Guzman, Raquel O. Rocha, Michael Richter, Richard Wilson
A Protein Kinase Coordinates Cycles Of Autophagy And Glutaminolysis In Invasive Hyphae Of The Fungus Magnaporthe Oryzae Within Rice Cells, Gang Li, Ziwen Gong, Nawaraj Dulal, Margarita Marroquin-Guzman, Raquel O. Rocha, Michael Richter, Richard Wilson
Department of Plant Pathology: Faculty Publications
The blast fungus Magnaporthe oryzae produces invasive hyphae in living rice cells during early infection, separated from the host cytoplasm by plantderived interfacial membranes. However, the mechanisms underpinning this intracellular biotrophic growth phase are poorly understood. Here, we show that the M. oryzae serine/threonine protein kinase Rim15 promotes biotrophic growth by coordinating cycles of autophagy and glutaminolysis in invasive hyphae. Alongside inducing autophagy, Rim15 phosphorylates NADdependent glutamate dehydrogenase, resulting in increased levels of α- ketoglutarate that reactivate target-of-rapamycin (TOR) kinase signaling, which inhibits autophagy. Deleting RIM15 attenuates invasive hyphal growth and triggers plant immunity; exogenous addition of α-ketoglutarate prevents these …
Lonnie Burt, Lonnie Burt
Lonnie Burt, Lonnie Burt
Oral History Project (all interviews)
Lonnie Burt recently retired as the Senior Food & Child Nutrition Services Director for the Hartford Public Schools where she oversaw the school meal program, including Breakfast, Lunch, Afterschool Snacks, At-Risk Supper, Summer Feeding and the Fresh Fruit and Vegetable Program Grant. She has worked in Child Nutrition for the nearly 35 years and has been in Hartford since 2004. Lonnie also works as an Adjunct Professor for Manchester Community College where she teaches classes in Nutrition, Human Resources, and Food Service Safety and Sanitation for the Hospitality Program. Lonnie is a Registered Dietitian who earned a Bachelor’s Degree in …
Tas Orders, Innovations And Challenges In Futures Markets, Fabio Mattos
Tas Orders, Innovations And Challenges In Futures Markets, Fabio Mattos
Cornhusker Economics
Futures contracts and futures exchanges were developed a long time ago in the process of evolution of commodity trading. They were created with the purpose of facilitating the buying and selling of commodities. Despite challenges along the way, they helped make commodity trading faster, easier, and more efficient for many buyers and sellers. Still today, futures exchanges are constantly looking for new ways to adjust to new developments in commodity markets and further facilitate trading. After all, as we have previously discussed in this space, futures exchanges provide a service to buyers and sellers, i.e., the marketplace to trade futures …
Evaluating Salmonella Cross Contamination In Raw Chicken Thighs In Simulated Post-Chill Tanks, Raziya Sadat
Evaluating Salmonella Cross Contamination In Raw Chicken Thighs In Simulated Post-Chill Tanks, Raziya Sadat
Department of Food Science and Technology: Dissertations, Theses, and Student Research
Salmonella contamination poses a significant risk to food safety, particularly in poultry products and public health. This study aims to investigate the effectiveness of peracetic acid (PAA) treatment in mitigating Salmonella cross-contamination in chicken thighs within simulated post-chill tanks, considering different inoculum concentrations and organic matter (OM) levels.
The experiment involved the use of five distinct Salmonella serovars to inoculate chicken thighs, which were categorized into two groups: higher inoculation level (ca. 7 log CFU/mL) and lower inoculation level (ca, 4 log CFU/mL). These groups underwent treatment with four different solutions, including 540 ppm PAA with 1.5% OM, 540 ppm …
An Observed Increase In Cardiovascular And Respiratory-Disease Related Hospitalizations And Mortality In An Area Surrounding A Hazardous Waste Thermal Treatment Plant, Liana Isabelle Dela Torre Baconguis
An Observed Increase In Cardiovascular And Respiratory-Disease Related Hospitalizations And Mortality In An Area Surrounding A Hazardous Waste Thermal Treatment Plant, Liana Isabelle Dela Torre Baconguis
LSU Master's Theses
Particulate matter (PM) pollution is highly correlated with respiratory and cardiovascular disease incidence. The generation of oxidative stress is a major way by which PM can damage the body. Environmentally persistent free radical-containing PM are generated by combustion processes and are capable of exerting increased damage on the respiratory and cardiovascular systems due to their ability to remain stable and regenerate reactive oxygen species for up to five years. Clean Harbors, LLC operates a thermal treatment plant near the city of Colfax, LA in Central Louisiana. Its regular open burning of explosives causes disturbances to the community, such as loud …
Microbe Hunters, Paul De Kruif
Microbe Hunters, Paul De Kruif
Zea E-Books Collection
Microbe Hunters by Paul de Kruif was first published in 1926 by Harcourt, Brace and Company, New York. It dramatically recounts the breakthrough discoveries of the fundamental elements of bacteriology. It features exciting profiles of Antony Leeuwenhoek, Lazzaro Spallanzani, Louis Pasteur, Robert Koch, Émile Roux, Emil Behring, Élie Metchnikoff, Theobald Smith, David Bruce, Ronald Ross, Battista Grassi, Walter Reed, and Paul Ehrlich. Their development of germ theory and its scientific proofs led to the first effective treatments for human diseases like anthrax, rabies, diptheria, malaria, sleeping sickness, syphilis, and yellow fever. They also made discoveries that saved the dairy, wine, …
Cardiovascular Sars-Cov-2 Tropism And Immunopathology, Oleksandr Dmytrenko
Cardiovascular Sars-Cov-2 Tropism And Immunopathology, Oleksandr Dmytrenko
Arts & Sciences Graduate Student Theses and Dissertations
Coronavirus Disease 2019 (COVID-19) is caused by SARS-CoV-2, a member of beta-coronaviridae family. This single-stranded RNA virus is transmitted through a respiratory route, binds to a host receptor ACE2 and enters lung pneumocytes, causing fulminant pulmonary disease in a subset of patients. In addition to pulmonary disease, SARS-CoV-2 can also lead to extrapulmonary manifestations, affecting brain, kidneys, blood vessels and heart. Cardiac complications are common in COVID-19 patients with both mild and severe clinical courses. However, it remains unclear which cardiac cell types are susceptible to SARS-CoV-2 and what the consequences of their infection are. In this work, I identified …
Characterization Of Subcellular Functional Domains In The Vesicular Glutamate Transporter 3-Expressing Retinal Amacrine Cell Using Correlative Light And Electron Microscopy, Karl Friedrichsen
Arts & Sciences Graduate Student Theses and Dissertations
The following work seeks to better understand how neurons process multiple streams of information within the branches of their dendritic arbors. We use correlated light and electron microscopy to capture both live subcellular calcium responses and detailed morphology and synaptic connectivity in a unique retinal amacrine cell in order to directly study the relationship between structure and function. The vesicular glutamate transporter 3-expressing amacrine cell (VG3) selectively integrates and segregates visual information within its arbor branches and provides multiple target neuron types with appropriate excitatory or inhibitory synaptic inputs. By reconstructing VG3 arbor branches, synapses, and connected cell types, we …
Evaluating Vaccine Management Strategies For Edwardsiella Ictaluri Infections In Zebrafish (Danio Rerio), Brandy Malbrough
Evaluating Vaccine Management Strategies For Edwardsiella Ictaluri Infections In Zebrafish (Danio Rerio), Brandy Malbrough
LSU Master's Theses
Aquaculture is a globally important industry that faces significant challenges due to infectious diseases, which can result in substantial financial losses. In 2011, a new strain of Edwardsiella ictaluri emerged as a major pathogen affecting zebrafish in the ornamental fish industry, leading to high mortality rates and posing a severe threat to the sector. Vaccines provide potential benefits for disease prevention in aquaculture, particularly live-attenuated vaccines (LAVs), which induce strong host immune responses. Bacterial attenuation for vaccine development has evolved from serial passage to more targeted genetic modification techniques. However, regulatory constraints limit the availability of licensed LAVs for aquaculture. …
Nutrient Content And Bioactive Compounds In Ornamental Type Sweetpotatoes, Sandeep Kaur Sran
Nutrient Content And Bioactive Compounds In Ornamental Type Sweetpotatoes, Sandeep Kaur Sran
LSU Master's Theses
Abstract
The leaf and root composition of different cultivars of ornamental sweetpotatoes (‘Blackie’, ‘Kakura’, ‘Manihi’, ‘Makatea’, ‘Tahiti’ and ‘Tatakoto’) were analyzed, and the impact of various factors on the levels of nutrients, vitamins, antioxidants, phenolic compounds, sugars, and organic acids in these sweetpotato cultivars were determined. The principal macronutrients found in sweetpotato foliage and roots were nitrogen (N), potassium (K), phosphorus (P), magnesium (Mg), calcium (Ca), and sulfur (S). Nitrogen was the most abundant macronutrient among all cultivars in sweetpotato foliage, whereas potassium was the most abundant macronutrient in sweetpotato roots. The principal micronutrients found in foliage and roots were …
Wave Attenuation Through Mangrove Forest Using Lidar Representation, Elizabeth Bogan
Wave Attenuation Through Mangrove Forest Using Lidar Representation, Elizabeth Bogan
LSU Master's Theses
Mangrove forests can be found along the world’s intertidal tropical and sub-tropical coastlines. These forested wetlands provide many ecosystem services, including supporting coastal food chains, trapping sediment, and shoreline stabilization. Mangroves are also known for flood damage mitigation by dissipating waves and surge during flooding events. Thus, coastal communities declare a vested interest in the performance of the forest to mitigate flood damage. Physical models using artificial mangrove structures have shown that red mangrove-dominated fringe forests can protect built infrastructure by reducing wave height due to increased drag. One way to estimate the contribution of red mangrove (Rhizophora mangle) prop …
Mettl3-Mediated M6a Modification Of Linc00839 Maintains Glioma Stem Cells And Radiation Resistance By Activating Wnt/Β-Catenin Signaling, Jianxing Yin, Fangshu Ding, Zhangchun Cheng, Xin Ge, Yanhui Li, Junxia Zhang, Zhumei Shi, Xu Qian, Yongping You, Zhiliang Ding, Jing Ji, Xiefeng Wang
Mettl3-Mediated M6a Modification Of Linc00839 Maintains Glioma Stem Cells And Radiation Resistance By Activating Wnt/Β-Catenin Signaling, Jianxing Yin, Fangshu Ding, Zhangchun Cheng, Xin Ge, Yanhui Li, Junxia Zhang, Zhumei Shi, Xu Qian, Yongping You, Zhiliang Ding, Jing Ji, Xiefeng Wang
Faculty, Staff and Student Publications
Long noncoding RNAs (lncRNAs) are involved in glioma initiation and progression. Glioma stem cells (GSCs) are essential for tumor initiation, maintenance, and therapeutic resistance. However, the biological functions and underlying mechanisms of lncRNAs in GSCs remain poorly understood. Here, we identified that LINC00839 was overexpressed in GSCs. A high level of LINC00839 was associated with GBM progression and radiation resistance. METTL3-mediated m6A modification on LINC00839 enhanced its expression in a YTHDF2-dependent manner. Mechanistically, LINC00839 functioned as a scaffold promoting c-Src-mediated phosphorylation of β-catenin, thereby inducing Wnt/β-catenin activation. Combinational use of celecoxib, an inhibitor of Wnt/β-catenin signaling, greatly sensitized GSCs to …
Pilot Testing Of A Non-Gaming Cognitive Battery In Expert Esports Athletes, Allison J. Brager, Patrick Belling, Jason Sada, Jeffrey Osgood, Bradley Fawver, Michael Dretsch
Pilot Testing Of A Non-Gaming Cognitive Battery In Expert Esports Athletes, Allison J. Brager, Patrick Belling, Jason Sada, Jeffrey Osgood, Bradley Fawver, Michael Dretsch
Journal for Sports Neuroscience
Introduction: The esports industry is rapidly expanding, making it imperative to identify common data elements of expert gamers for the purposes of performance optimization and enhancement. We aimed to measure cognitive performance in a convenient sample of expert esports athletes, as well as to determine if cognitive performance of these individuals could be further enhanced through a novel non-gaming neurocognitive test battery.
Methods: Elite esports athletes (n = 5) participated in a four-day cognitive and strength & conditioning program at the Sports Academy (Thousand Oaks, CA). Cognitive performance was assessed through five tasks of increasing cognitive load. Baseline …
The Impact Of Covid-19 On The Financial Performance Of Largest Teaching Hospitals, Tiffany Champagne-Langabeer, James R Langabeer
The Impact Of Covid-19 On The Financial Performance Of Largest Teaching Hospitals, Tiffany Champagne-Langabeer, James R Langabeer
Faculty, Staff and Student Publications
The COVID-19 pandemic disrupted hospital operations. Anecdotal evidence suggests financial performance likewise suffered, yet little empirical research supports this claim. This study aimed to explore the impact of the pandemic on the financial performance of the most prominent academic hospitals in the United States. Data from the 115 largest major teaching hospitals in the United States were extracted from the American Hospital Directory for three years (2019-2021). We hypothesized that the year and region would moderate the relationship between a hospital's return on assets (financial performance) and specific operational variables. We found evidence through descriptive statistics and multivariate moderated regressions …