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Articles 34141 - 34170 of 256001
Full-Text Articles in Life Sciences
Brain Microvascular Endothelial Cells Possess A Second Cilium That Arises From The Daughter Centriole, Karthikeyan Thirugnanam, Ankan Gupta, Francisco Nunez, Shubhangi Prabhudesai, Amy Y. Pan, Surya M. Nauli, Ramani Ramchandran
Brain Microvascular Endothelial Cells Possess A Second Cilium That Arises From The Daughter Centriole, Karthikeyan Thirugnanam, Ankan Gupta, Francisco Nunez, Shubhangi Prabhudesai, Amy Y. Pan, Surya M. Nauli, Ramani Ramchandran
Pharmacy Faculty Articles and Research
Primary cilia from the brain microvascular endothelial cells (ECs) are specialized cell-surface organelles involved in mediating sensory perception, cell signaling, and vascular stability. Immunofluorescence (IF) analysis of human primary brain microvascular ECs reveals two cilia per cell. To confirm the in vitro observation of the two-cilia phenotype in human primary brain ECs, ECs isolated from mouse brain were cultured and stained for cilium. Indeed, brain ECs from a ciliopathic mouse (polycystic kidney disease or Pkd2−/−) also possess more than one cilium. Primary cilium emerges from the mother centriole. Centriole analysis by IF suggests that in brain ECs, markers …
Manure And Wastewater Sampling Guide, Rhonda Miller, Cody Zesiger, Kalen Taylor, Matt Yost
Manure And Wastewater Sampling Guide, Rhonda Miller, Cody Zesiger, Kalen Taylor, Matt Yost
All Current Publications
Manure and wastewater are resources that can reduce your fertilizer needs and help improve soil and your bottom line. It is important that manure and wastewater be sampled and tested so one can apply the manure and nutrients appropriately. Sampling and analysis should occur as close to land application as possible as nutrient concentration in manure and wastewater can change over time due to runoff, leaching, and changes in moisture percentage. Nitrogen can also be lost due to volatilization. There are two primary approaches for when to sample: (1) just before land application, and (2) at the time of land …
The Deubiquitinase Zranb1 Is An E3 Ubiquitin Ligase For Slc7a11 And Regulates Ferroptotic Resistance, Shan Huang, Qimin Zhang, Manyu Zhao, Xing Wang, Yilei Zhang, Peijing Zhang
The Deubiquitinase Zranb1 Is An E3 Ubiquitin Ligase For Slc7a11 And Regulates Ferroptotic Resistance, Shan Huang, Qimin Zhang, Manyu Zhao, Xing Wang, Yilei Zhang, Peijing Zhang
Faculty, Staff and Student Publications
The dependency of cancer cells on iron increases their susceptibility to ferroptosis, thus providing new opportunities for patients with treatment-resistant tumors. However, we show that lipid peroxidation, a hallmark of ferroptosis, was found in various areas of patient samples, indicating the potential resistance of ferroptosis. Using whole deubiquitinases (DUBs) sgRNA screening, we found that loss of ZRANB1 confers cancer cell resistance to ferroptosis. Intriguingly, functional studies revealed that ZRANB1 ubiquitinates and represses SLC7A11 expression as an E3 ubiquitin ligase and that ZRANB1 inhibits glutathione (GSH) synthesis through SLC7A11 degradation, leading to elevated lipid peroxidation and ferroptosis. Deletion of the region …
Aptamers As Potential Therapeutic Tools For Ovarian Cancer: Advancements And Challenges, Wojciech Szymanowski, Anna Szymanowska, Anna Bielawska, Gabriel Lopez-Berestein, Cristian Rodriguez-Aguayo
Aptamers As Potential Therapeutic Tools For Ovarian Cancer: Advancements And Challenges, Wojciech Szymanowski, Anna Szymanowska, Anna Bielawska, Gabriel Lopez-Berestein, Cristian Rodriguez-Aguayo
Faculty, Staff and Student Publications
Ovarian cancer (OC) is the most common lethal gynecologic cause of death in women worldwide, with a high mortality rate and increasing incidence. Despite advancements in the treatment, most OC patients still die from their disease due to late-stage diagnosis, the lack of effective diagnostic methods, and relapses. Aptamers, synthetic, short single-stranded oligonucleotides, have emerged as promising anticancer therapeutics. Their ability to selectively bind to target molecules, including cancer-related proteins and receptors, has revolutionized drug discovery and biomarker identification. Aptamers offer unique insights into the molecular pathways involved in cancer development and progression. Moreover, they show immense potential as drug …
Ischemic Bowel Associated With Newly Diagnosed Patent Foramen Ovale, Hannah Hong, Deanna Glassman, Shannon Neville Westin
Ischemic Bowel Associated With Newly Diagnosed Patent Foramen Ovale, Hannah Hong, Deanna Glassman, Shannon Neville Westin
Faculty, Staff and Student Publications
No abstract provided.
Msis-Capaldi: Using Mathematical Models To Evaluate Strategies For Managing White-Nose Syndrome In Little Brown Bats, Julie Blackwood
Msis-Capaldi: Using Mathematical Models To Evaluate Strategies For Managing White-Nose Syndrome In Little Brown Bats, Julie Blackwood
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
An Integrated Pest Management Model Incorporating Prey Refuge And Movement Between Regions, Aashima Singh Sisodia, Timothy Comar
An Integrated Pest Management Model Incorporating Prey Refuge And Movement Between Regions, Aashima Singh Sisodia, Timothy Comar
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Saving The Devils Is In The Details, Megan O. Powell
Saving The Devils Is In The Details, Megan O. Powell
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Incorporating Adaptive Human Behavior Into Epidemiological Models Using Equation Learning, Austin Barton, Jordan Klein, Jonathan Greer, Kevin Flores, Patrick Haughey
Incorporating Adaptive Human Behavior Into Epidemiological Models Using Equation Learning, Austin Barton, Jordan Klein, Jonathan Greer, Kevin Flores, Patrick Haughey
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Baa-Ttling Sore Mouth In Sheep With Mathematical Modeling, David C. Elzinga, W. Christopher Strickland
Baa-Ttling Sore Mouth In Sheep With Mathematical Modeling, David C. Elzinga, W. Christopher Strickland
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
A Multi-Model Approach To Understanding Growth, Reproduction, And Life History Strategies In Bromeliads, Erin N. Bodine
A Multi-Model Approach To Understanding Growth, Reproduction, And Life History Strategies In Bromeliads, Erin N. Bodine
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
From Formulas To Futures: Mathematical Insights Into Endosomal Escape, Fnu Nisha
From Formulas To Futures: Mathematical Insights Into Endosomal Escape, Fnu Nisha
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Human Behavior And Viral Evolution Of Emerging Infections, Asma Azizi
Human Behavior And Viral Evolution Of Emerging Infections, Asma Azizi
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Using A Coupled Integral Projection Model To Investigate Interspecific Competition During An Invasion: An Application To Silver Carp (Hypophthalmichthys Molitrix) And Gizzard Shad (Dorosoma Cepedianum), James Peirce
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Distinguishing Community Assembly Through Functional Redundancy Models., Sandra A. Tsiorintsoa, Sharon Bewick, Matthew Macauley
Distinguishing Community Assembly Through Functional Redundancy Models., Sandra A. Tsiorintsoa, Sharon Bewick, Matthew Macauley
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Thoracoabdominal Asynchrony In A Virtual Preterm Infant: Computational Modeling And Analysis, Richard R. Foster, Bradford Smith, Laura Ellwein Fix
Thoracoabdominal Asynchrony In A Virtual Preterm Infant: Computational Modeling And Analysis, Richard R. Foster, Bradford Smith, Laura Ellwein Fix
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Nutrient Driven Dynamics Of Ecosystem Diseases, Rebecca Everett
Nutrient Driven Dynamics Of Ecosystem Diseases, Rebecca Everett
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
The Effect Of Disturbances On Biodiversity In A Forest, David Chan, Benjamin S. Ramage
The Effect Of Disturbances On Biodiversity In A Forest, David Chan, Benjamin S. Ramage
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Impacts On Malaria Transmission Of Altered Biogenic Amine Levels In {\It Anopheles} Mosquitoes: Insights From A Mathematical Model, Michael Robert
Impacts On Malaria Transmission Of Altered Biogenic Amine Levels In {\It Anopheles} Mosquitoes: Insights From A Mathematical Model, Michael Robert
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Modeling Single And Multiple Pacemaker Interaction In Jellyfish Locomotion, Alexander Hoover
Modeling Single And Multiple Pacemaker Interaction In Jellyfish Locomotion, Alexander Hoover
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Minimization Of Diet For Optimum Consumption Using Linear Programming, Nita Ngozi Ezekwem, Aditi Ghosh
Minimization Of Diet For Optimum Consumption Using Linear Programming, Nita Ngozi Ezekwem, Aditi Ghosh
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Gaff-Msis-Ledder: Agent-Based Modeling Of Tick Population Genetics, Holly Gaff
Gaff-Msis-Ledder: Agent-Based Modeling Of Tick Population Genetics, Holly Gaff
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Msis-Kondrashov: Does Humanizing Scientists Increase Student Science Identity And Quantitative Skills?, Rachel Hartnett
Msis-Kondrashov: Does Humanizing Scientists Increase Student Science Identity And Quantitative Skills?, Rachel Hartnett
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Intracellular Transport And Filament Organization In Neurons, Maria-Veronica Ciocanel
Intracellular Transport And Filament Organization In Neurons, Maria-Veronica Ciocanel
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Modeling The Long-Distance Effects Of Predation, Henry Ogu
Modeling The Long-Distance Effects Of Predation, Henry Ogu
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Msis-Glenn: Natural Selection In Wolves Leads To Domesticated Dogs Predicted By Agent-Based Model Simulations, Alex Capaldi, David C. Elzinga
Msis-Glenn: Natural Selection In Wolves Leads To Domesticated Dogs Predicted By Agent-Based Model Simulations, Alex Capaldi, David C. Elzinga
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Langevin Dynamic Models For Smfret Dynamic Shift, David Frost, Keisha Cook Dr, Hugo Sanabria Dr
Langevin Dynamic Models For Smfret Dynamic Shift, David Frost, Keisha Cook Dr, Hugo Sanabria Dr
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Msis-Udiani: Tactics And Trade-Offs: The Evolution Of Host Resource Provisioning In Microbiome Management, Oyita Udiani, Nina Fefferman
Msis-Udiani: Tactics And Trade-Offs: The Evolution Of Host Resource Provisioning In Microbiome Management, Oyita Udiani, Nina Fefferman
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Msis-Kondrashov: Data-Driven Modeling With Integral Projection Models, James Peirce
Msis-Kondrashov: Data-Driven Modeling With Integral Projection Models, James Peirce
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Msis-Kadelka: Modularizing The Control Search For Biological Systems, David Murrugarra
Msis-Kadelka: Modularizing The Control Search For Biological Systems, David Murrugarra
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.