Life Sciences Commons^™

Archery: A Prospective Observational Study Of Artificial Intelligence-Based Radiotherapy Treatment Planning For Cervical, Head And Neck And Prostate Cancer – Study Protocol, Ajay Aggarwal, Laurence Edward Court, Peter Hoskin, Isabella Jacques, Mariana Kroiss, Sarbani Laskar, Yolande Lievens, Indranil Mallick, Rozita Abdul Malik, Elizabeth Miles, Issa Mohamad, Claire Murphy, Matthew Nankivell, Jeannette Parkes, Mahesh Parmar, Carol Roach, Hannah Simonds, Julie Torode, Barbara Vanderstraeten, Ruth Langley

Faculty, Staff and Student Publications

INTRODUCTION: Fifty per cent of patients with cancer require radiotherapy during their disease course, however, only 10%-40% of patients in low-income and middle-income countries (LMICs) have access to it. A shortfall in specialised workforce has been identified as the most significant barrier to expanding radiotherapy capacity. Artificial intelligence (AI)-based software has been developed to automate both the delineation of anatomical target structures and the definition of the position, size and shape of the radiation beams. Proposed advantages include improved treatment accuracy, as well as a reduction in the time (from weeks to minutes) and human resources needed to deliver radiotherapy. …

Physical Characteristics, Movement Pattern And Heart Rate Response Of Indian Cricketers During Batting In Twenty20 (T20) Matches, Subhashis Biswas, Rupayan Bhattacharya, Arnab Das

International Journal of Exercise Science

International Journal of Exercise Science 16(6): 1413-1425, 2023. The study aims to provide a morphological profile of Indian cricketers and find physiological demands and positional differences of the batsmen in T20 matches according to their batting order. Eighty-three male cricketers (age: 17.93 ± 2.23 years) participated in this study and categorized into upper-order (n = 36), middle-order (n = 35) and lower-order (n = 12) batsmen. Height, weight, body fat%, and somatotype were measured. Movement analysis and heart rate (HR) responses were recorded during batting in T20 matches using PolarV800 smart-watch and H7 HR sensor. Descriptive statistics, …

Conservation Agriculture And Cover Crop Adoption By Smallholder Farmers In Cambodia: Understanding Perceptions, Challenges, And Opportunities For Soil Improvement, Presley Nickens, David R. Ader, Max C. Miller, Ii, Pao Srean, Tom Gill, Sovanneary Huot

Agricultural and Environmental Sciences Faculty Research

Practical solutions for soil conservation are needed to ensure sustainable food production. Conservation agriculture and the use of cover crops are promising strategies for soil improvement in agricultural systems. These strategies are being promoted in Cambodia to address rapidly declining soil fertility; however, there is a lack of insight into the perceptions of Cambodian smallholders towards cover cropping within a conservation agriculture approach. A greater understanding of the utilization and perceptions of cover crops is needed to increase adoption and prevent further soil degradation. This study utilized a mixed methods approach with quantitative data from a farmer survey and qualitative …

Zea Mays Genotype Influences Microbial And Viral Rhizobiome Community Structure, Pooja Yadav, Amanda Quattrone, Yuguo Yang, Jacob Owens, Rebecca Kiat, Thirumurugen Kuppusamy, Sabrina E. Russo

School of Biological Sciences: Faculty Publications

Plant genotype is recognized to contribute to variations in microbial community structure in the rhizosphere, soil adherent to roots. However, the extent to which the viral community varies has remained poorly understood and has the potential to contribute to variation in soil microbial communities. Here we cultivated replicates of two Zea mays genotypes, parviglumis and B73, in a greenhouse and harvested the rhizobiome (rhizoplane and rhizosphere) to identify the abundance of cells and viruses as well as rhizobiome microbial and viral community using 16S rRNA gene amplicon sequencing and genome resolved metagenomics. Our results demonstrated that viruses exceeded microbial abundance …

Applying The Fast Fit Test Method For Quantitative Cnc To The Qualitative Fit Test Method Utilizing And Approved Reference Method And A Modified Reference Method, Mckenna Kaelber

Graduate Theses & Non-Theses

N95 respirators are the most utilized respirator in the healthcare sector, and when properly fitted, protect workers from biological and chemical exposures. A respirator fit test is a protocol used to assess the seal between the user’s face and the respirator. Quantitative and Qualitative methods are both approved and used for respirator fit testing. Quantitative Condensation Nuclei Counting (CNC) uses instrumentation to measure the particles on the inside and outside of the respirator and calculates a fit factor, indicating how well the respirator fits. Qualitative fit testing (QLFT) relies on the individual’s ability to detect a challenge agent while wearing …

Jack Crevalle Neurocranium, Rodolfo A. Heredia, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.

The Unexpected Significance Of Myosin A In Organization Of M-Line Protein Unc-89/Obscurin Within Striated Muscle Cells Of Caenorhabditis Elegans, Kar Men Lee

Honors Theses

This research investigates the unexpected significance of Myosin A in the organization of M-line protein UNC-89/obscurin within striated muscle cells of the nematode Caenorhabditis elegans (C. elegans). The study employs immunofluorescence techniques to examine the spatial and temporal dynamics of UNC-89/obscurin and Myosin A during embryonic development. The sarcomere, a fundamental unit in muscle cells, is governed by the 'sliding filament model,' where the M-line serves as a crucial anchor for Myosin A. This research seeks to understand the relationship between muscle function in humans and C. elegans, utilizing the latter's simple anatomy and genetic tractability. The …

Comparing Ergonomic Hazard Control Methods For Rock Drilling, Mickenzie Alt

Graduate Theses & Non-Theses

This study compares data from a new rock drill (Epiroc HRD-100) to a previous study's data from a jackleg drill. The HRD-100 is a handheld hydraulic drill. It employs vibration dampening by design and a soft-start function, to reduce vibration exposures and a hydraulic feed leg that may aid in the reduction of required exertion on the part of the operator, as compared to that ofa jackleg drill. A 2007 study from South Africa found that a hydraulic drill produced a higher degree of vibration than a pneumatic drill (Phillips et al., 2007). Epiroc's product brochure lists HRD acceleration at …

Recognizing Power And Control When Planning Your Estate, Allan Vyhnalek

Cornhusker Economics

The older generations have spent their entire professional lives using the power and control that they accumulated through hard work and their long tenures. Having them retire and give up that control and power is difficult for some in those generations. Overall, it is challenging for them to give up control or power.

Brown Bullhead Catfish (Ameiurus Nebulosus) Neurocranium, Reginald Leon Kempson Iii, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

Neurocranium from [6.3] cm total length (30 cm) [Brown Bullhead Catfish (Ameiurus nebulosus)], collected from [Dr.Kerstetters lab] on [6/December/2023] by [Reginald Kempson III]

Pediatric Parosteal Osteosarcoma Of The Distal Radius Causing Extensive Erosive Mass Effect Of The Adjacent Ulna: A Case Report, Andrea Perloff, Sehoon Park, Robert Panganiban, John Devries

Department of Orthopaedics Faculty Research

Introduction: Parosteal osteosarcomas are low-grade bony malignancies that are treated primarily with surgical resection and reconstruction. This report discusses a unique case of a pediatric patient who presented with a parosteal osteosarcoma of the distal radius causing extensive erosive mass effect and growth disturbance of the adjacent ulna. Likely due to their slow-growing nonaggressive nature, parosteal osteosarcomas have not been previously described to abut adjacent bony structures through direct contact. The patient presented in a significantly delayed manner due to social circumstances, inadvertently revealing this novel behavior. This report reviews this rare case and describes the current understanding of this …

Simultaneous Detection Of Methylation And Genetic Variations Of Bcr-Abl1 Gene By Nanopore Cas9-Targeted Sequencing, Shuilian Xie, Ying Yang, Junjie Zhang, Menglin Zhu, Wang Li, Mengting Li, Yijian Chen, Hailiang Li, Weidan Lun, Weelic Chong, Shaogui Wan

Department of Medicine Faculty Papers

No abstract provided.

Snail Races: An Inquiry-Based Approach To Learn Invasive Species Ecology, Emma Grindle, Heather E. Bergan-Roller, Ashton Johnson, Grace Lunaburg, Jennifer A.H. Koop

Faculty Articles, Papers, and Other Scholarship

Inquiry-based lessons allow learning that is hands-on and student-driven, fostering engagement and retention of knowledge in any discipline. Here, we use this learning framework to engage students in exploring the effects of biotic and abiotic factors on animal dispersal as a means of connecting students to multiple ecological concepts. Instructors are provided with a guided lecture on key ecological concepts including the impacts of invasive species, dispersal mechanisms, and species interactions with the environment. Furthermore, the interactive lecture introduces students to the snail study system and explains the experimental process, which involves low-cost, readily available materials (e.g., kiddie pools). Students …

We Are The Reason We Stand Still In The Face Of Climate Change., Sydney Hemp

Honors Theses

Many different factors can impact the way any information is received but it is especially important to see how scientific information is received because it is often backed up by a great deal of evidence, especially in the case of global climate change. Many of these factors have nothing to do with science and everything to do with social influences, political parties, and other demographic measures. Discussion of these relationships is important when discussing communication in a broad sense, but it can be even more important when bringing up things like global climate change, which has become a political topic …

Delta-9-Tetrahydrocannabinol And Cannabidiol Effect On Dopamine Transporter Expression And Function, Delia M. Guzman

Student Theses

Drug addiction is a major endemic crisis in the United States with a higher prevalence than any other country. Marijuana and hallucinogens make up a great percentage of the drugs of abuse in Americans ranging from 15 to 64 years old. Marijuana contains over 500 active compounds that contribute to its effects, the major components being delta-9-tetrahydrocannabinol (Δ-9-THC) and cannabidiol (CBD). Understanding the pharmacological mechanism as well as the effects that they elicit through the dopaminergic reward system is a key factor in being able to understand why addiction is so prevalent in our society. This research was aimed to …

Formation Of Hollow Solid Lipid Microparticles From Natural Waxes Using Supercritical Carbon Dioxide, Purlen Sezer Okur, Deniz Ciftci, Ozan Ciftci

Department of Food Science and Technology: Faculty Publications

In this study, the potential of natural waxes, namely, candelilla wax (CLW) and carnauba wax (CW), was explored to form extra-hard shell hollow solid lipid particles using a particle formation process based on supercritical fluid technology. Melting behavior and volumetric expansion of CLW and CW in pressurized CO₂ were investigated as a function of pressure. The melting point of waxes decreased linearly with increasing pressures up to a certain level; then stayed constant regardless of further elevated pressures. The highest melting point depressions of 13.0% and 8.3% were observed for CLW and CW at 140 and 130 bar CO …

Novel Fire And Herbivory Regime Impacts On Forest Regeneration And Plant Community Assembly, Devri A. Tanner

Theses and Dissertations

Human activities are increasing the occurrence of megafires that have the potential to alter the ecology of forest ecosystems. The objective of this study was to understand the impact of a 610 km2 megafire on patterns of forest regeneration and herbivory of three forest types (aspen/fir, oak/maple, and pinyon/juniper) within the burn scar. Sapling density, meristem removal, and height were measured across a transect network spanning the area of the burn scar over three years from 2019-2021. The network consisted of 17 burned/unburned transect pairs in adjacent burned/unburned forest stands (6 aspen/fir, 5 oak/maple, and 6 pinyon/juniper). Species that regenerated …

Health Care Providers’ Experiences With Integrated Care Services Needed To Treat Patients With Type 3 Compared To Type 2 Diabetes, Sharon Hope Jaycox

Walden Dissertations and Doctoral Studies

No abstract provided.

Fishing And Fear Effects Interact To Shape Herbivory On Coral Reefs, Bethany M. Tilton

All HCAS Student Capstones, Theses, and Dissertations

Predation influences animal behavior and shapes ecological structure and function through lethal effects and fear effects. On coral reefs, fear effects can alter the distribution and intensity of herbivory by herbivorous reef fishes. This includes the browsing functional group, which potentially reverses macroalgal phase shifts and promotes reef recovery. Herbivory by multiple functional groups may increase on coral reefs through the use of NTZs (no-take zones) but few studies have examined the extent to which small-scale NTZs (< 0.5 km²) influence fear effects and perceived predator presence on reefs. This study aimed to determine whether fear effects on browsers on …

A Rapid Site Selection Assessment As An Indicator Of Stony Coral Microfragment Outplant Success, John J. Alfirevich

All HCAS Student Capstones, Theses, and Dissertations

Microfragmentation of massive stony coral species is a technique being utilized to propagate corals asexually to help restore coral reefs. Microfragmentation consists of cutting corals into 3 cm diameter or less fragments, which boosts growth rates. However, in some locations the size of microfragments make them vulnerable to parrotfish predation and benthic overgrowth, reducing survival. As such, a method to identify key site characteristics which promotes microfragment outplant success, particularly one that can be performed quickly across multiple areas is needed. A rapid site assessment conducted prior to microfragment outplanting was performed at 12 randomly selected sites within the Kristin …

Demographic History Shapes North American Gray Wolf Genomic Diversity And Informs Species' Conservation, Bridgett M. Vonholdt, Daniel R. Stahler, Kristin Brzeski, Marco Musiani, Rolf O. Peterson, Michael Phillips, John Stephenson, Kent Laudon, Erin Meredith, John Vucetich, Jennifer A. Leonard, Robert K. Wayne

Michigan Tech Publications

Effective population size estimates are critical information needed for evolutionary predictions and conservation decisions. This is particularly true for species with social factors that restrict access to breeding or experience repeated fluctuations in population size across generations. We investigated the genomic estimates of effective population size along with diversity, subdivision, and inbreeding from 162,109 minimally filtered and 81,595 statistically neutral and unlinked SNPs genotyped in 437 grey wolf samples from North America collected between 1986 and 2021. We found genetic structure across North America, represented by three distinct demographic histories of western, central, and eastern regions of the continent. Further, …

Effects Of Dimerization On The Deacylase Activities Of Human Sirt2., Jie Yang, Nathan I Nicely, Brian P Weiser

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Human sirtuin isoform 2 (SIRT2) is an NAD+-dependent enzyme that functions as a lysine deacetylase and defatty-acylase. Here, we report that SIRT2 readily dimerizes in solution and in cells and that dimerization affects its ability to remove different acyl modifications from substrates. Dimerization of recombinant SIRT2 was revealed with analytical size exclusion chromatography and chemical cross-linking. Dimerized SIRT2 dissociates into monomers upon binding long fatty acylated substrates (decanoyl-, dodecanoyl-, and myristoyl-lysine). However, we did not observe dissociation of dimeric SIRT2 in the presence of acetyl-lysine. Analysis of X-ray crystal structures led us to discover a SIRT2 double mutant (Q142A/E340A) that …

Association Between Viral Infections And Glioma Risk: A Two-Sample Bidirectional Mendelian Randomization Analysis, Sheng Zhong, Wenzhuo Yang, Zhiyun Zhang, Yangyiran Xie, Lin Pan, Jiaxin Ren, Fei Ren, Yifan Li, Haoqun Xie, Hongyu Chen, Davy Deng, Jie Lu, Hui Li, Bo Wu, Youqi Chen, Fei Peng, Vinay K Puduvalli, Ke Sai, Yunqian Li, Ye Cheng, Yonggao Mou

Faculty, Staff and Student Publications

Background: Glioma is one of the leading types of brain tumor, but few etiologic factors of primary glioma have been identified. Previous observational research has shown an association between viral infection and glioma risk. In this study, we used Mendelian randomization (MR) analysis to explore the direction and magnitude of the causal relationship between viral infection and glioma.

Methods: We conducted a two-sample bidirectional MR analysis using genome-wide association study (GWAS) data. Summary statistics data of glioma were collected from the largest meta-analysis GWAS, involving 12,488 cases and 18,169 controls. Single-nucleotide polymorphisms (SNPs) associated with exposures were used as instrumental …

Gag Grouper (Mycteroperca Microlepis) Neurocranium, Sierra Potts, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

10 cm neurocranium from Gag Grouper, Mycteroperca microlepis, collected from Snapper Mike's on 05/11/2023 by Sierra Potts

Tidygeo Preparing Analysis-Ready Datasets From Gene Expression Omnibus, Avery Mecham, Ashlie Stephenson, Badi I. Quinteros, Grace S. Brown, Stephen R. Piccolo

Faculty Publications

TidyGEO is a Web-based tool for downloading, tidying, and reformatting data series from Gene Expression Omnibus (GEO). As a freely accessible repository with data from over 6 million biological samples across more than 4000 organisms, GEO provides diverse opportunities for secondary research. Although scientists may find assay data relevant to a given research question, most analyses require sample-level annotations. In GEO, such annotations are stored alongside assay data in delimited, text-based files. However, the structure and semantics of the annotations vary widely from one series to another, and many annotations are not useful for analysis purposes. Thus, every GEO series …

Resolution Of The Tetrabothrius Jagerskioeldi Cryptic Species Complex Among Holarctic Alcidae (Charadriiformes): Cestodes Among Fraterculinae—Exploring Marine Diversity, Host Range, And Dynamic Oceanography In The Greater North Pacific, Eric P. Hoberg, Kaylen Marie Soudachanh, Svetlana K. Bondarenko

MANTER: Journal of Parasite Biodiversity

In the biosphere, limits for diversity among species, communities, and biomes are revealed through intensive and extensive field-based inventory and assembly of voucher specimens and associated informatics examined in a phylogenetic, historical, ecological, and biogeographic arena. Archival resources for specimens and information contribute to a cumulative view of faunal structure and assembly under a comparative umbrella. Ultimately, species definitions, and inclusive partitions among populations and lineages, are fundamental in articulating hypotheses that examine interactions about evolution, the nature of organisms, and the condition of environments across space and time. We conclude our proposals establishing species limits for tapeworms of the …

Oregon State Rank Assessment For Bonneville Redside Shiner (Richardsonius Balteatus Hydrophlox), Misty Nelson

Institute for Natural Resources Publications

Oregon state conservation status assessment for Bonnevile redside shiner (Richardsonius balteatus hydrophlox) using NatureServe methodology, 2023.

Emerging Trends In Wheat (Triticum Spp.) Breeding: Implications For The Future, Mujahid Alam, P. Stephen Baenziger, Katherine Anna Frels

Department of Agronomy and Horticulture: Faculty Publications

Wheat (Triticum spp and, particularly, T. aestivum L.) is an essential cereal with increased human and animal nutritional demand. Therefore, there is a need to enhance wheat yield and genetic gain using modern breeding technologies alongside proven methods to achieve the necessary increases in productivity. These modern technologies will allow breeders to develop improved wheat cultivars more quickly and efficiently. This review aims to highlight the emerging technological trends used worldwide in wheat breeding, with a focus on enhancing wheat yield. The key technologies for introducing variation (hybridization among the species, synthetic wheat, and hybridization; genetically modified wheat; transgenic …

Complete Genome Sequences Of Cluster F1 And Cluster B1 Mycobacterium Smegmatis Phages Karhdo And Basato, Jireh Kim, Carlos Herrera, Wai Yan Aung, Gino Pablo Gonzales Boyles, Carmina Chavez, Mona Cibulka, Emma Foley, Jose Guerra, Disha Byadarahalli Mohan Kumar, Willow Levrant, Lewis Lim, Jose Llanes, Zachary Kamuela O'Brian, Art Pagaduan, Justin Aaron Richardson, Khristian Rosales, James Schrecengost, Tommy Shin, Gabriel Strong-Lundquist, Winnie Tat, Fritz Vanderford, Isabelle Vrinceanu, Vicky Wang, Stephanie Yang, Christy Strong, Philippos K. Tsourkas, Kurt Regner

Life Sciences Faculty Research

We present the complete genome sequences of Mycobacterium smegmatis phages Karhdo and Basato, isolated in Clark County, Nevada. The phages were isolated and annotated by students enrolled in undergraduate research courses over two semesters at the University of Nevada, Las Vegas.

Nonan Gaitprint: An Imu Gait Database Of Healthy Young Adults, Tyler M. Wiles, Madhur Mangalam, Joel H. Sommerfeld, Seung Kyeom Kim, Kolby J. Brink, Anaëlle Charles, Alli Grunkemeyer, Marilena Kalaitzi Manifrenti, Spyridon Mastorakis, Nicholas Stergiou, Aaron Likens

Journal Articles

An ongoing thrust of research focused on human gait pertains to identifying individuals based on gait patterns. However, no existing gait database supports modeling efforts to assess gait patterns unique to individuals. Hence, we introduce the Nonlinear Analysis Core (NONAN) GaitPrint database containing whole body kinematics and foot placement during self-paced overground walking on a 200-meter looping indoor track. Noraxon Ultium MotionTM inertial measurement unit (IMU) sensors sampled the motion of 35 healthy young adults (19–35 years old; 18 men and 17 women; mean ± 1 s.d. age: 24.6 ± 2.7 years; height: 1.73 ± 0.78 m; body mass: …