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Articles 31231 - 31260 of 255942

Full-Text Articles in Life Sciences

The Utility Of Visual Supports To Reinforce Healthy Dietary Behaviors In Children With Autism Spectrum Disorder: A Narrative Review, Allie Steffensen Jan 2024

The Utility Of Visual Supports To Reinforce Healthy Dietary Behaviors In Children With Autism Spectrum Disorder: A Narrative Review, Allie Steffensen

Health and Nutritional Sciences Graduate Students Plan B Capstone Projects

Purpose
The purpose of this narrative review is to synthesize the current literature on both eating/mealtime behaviors of children with ASD and visual support interventions in the same population. This narrative review aims to establish a rationale for the use of visual supports as a dietary behavior intervention for children with ASD.

Methods
This narrative review was conducted between September 2022 and December 2022. Because this narrative review has such a broad scope, a variety of articles were reviewed in the search, including primary research, systematic reviews, meta-analyses, literature reviews, observational studies, single-case studies, cohort studies, and cross-sectional studies. Articles …


Pathological Characterization Of Cryptosporidiosis In Naturally Infected Hybrid Converter Breeds Of Meleagris Gallopavo, Shady Shalaby, Walaa Awadin, Sanaa Salem, Ahmed El- Shaieb Jan 2024

Pathological Characterization Of Cryptosporidiosis In Naturally Infected Hybrid Converter Breeds Of Meleagris Gallopavo, Shady Shalaby, Walaa Awadin, Sanaa Salem, Ahmed El- Shaieb

Mansoura Veterinary Medical Journal

Background: Rearing of the hybrid converter breed of turkey (Meleagris gallopavo) is becoming more popular in Egyptian farms because of its high meat production; however, many pathogens affect this benefit.

Objectives: This study aimed to investigate the occurrence and pathological impact of cryptosporidiosis in hybrid converter breeds.

Methods: Regular visits to turkey farms of hybrid converter breeds in the delta region of Egypt were conducted during 2022 and 2023. Clinical examination of the diseased birds was performed and recorded. Following the clinical examination, the diseased turkeys were euthanized and necropsied. Freshly dead birds were then necropsied. The …


Disorganization Of Actin Within The Shafts Of Stereocilia Is A Key Difference Between Temporary And Permanent Noise-Induced Hearing Loss (Nihl), Shadan Hadi Jan 2024

Disorganization Of Actin Within The Shafts Of Stereocilia Is A Key Difference Between Temporary And Permanent Noise-Induced Hearing Loss (Nihl), Shadan Hadi

Theses and Dissertations--Physiology

During sound stimulation, mechanosensory stereocilia of the auditory hair cell pivot around their bases, where their actin cores become denser and form rootlets protruding into the cuticular plate. It is believed that actin-based cuticular plate provides a stable mechanical support for stereocilia, while rootles are responsible for their pivotal flexibility and life-long resilience to mechanical stimuli. Not surprisingly, damage to the stereocilia bundles is known as a hallmark of permanent noise-induced hearing loss (NIHL). Yet, despite decades of NIHL studies, it is still unknown which ultrastructural changes in the stereocilia bundles are evoked directly by mechanical overstimulation.

Here, we explored …


Differential Effects Of Traumatic Brain Injury On Preinjury And Postinjury Born Hippocampal Neural Precursor Cells, Hannah Downing Jan 2024

Differential Effects Of Traumatic Brain Injury On Preinjury And Postinjury Born Hippocampal Neural Precursor Cells, Hannah Downing

Theses and Dissertations--Physiology

Moderate contusive traumatic brain injury (TBI) results in neuronal cell death in the cortex as well as cell death and damage in underlying structures, including the hippocampus. The hippocampus is critically involved in learning and memory and is one of two regions in the brain capable of undergoing neurogenesis throughout adulthood. Adult hippocampal neurogenesis is a complex sequence of events necessary for a neural progenitor cell (NPC) to differentiate into a mature granule cell neuron located in the granule cell layer of the dentate gyrus. TBI results in a preferential loss of immature neurons in the granule cell layer of …


Wildar Northeast Florida, Kailan Sindelar Jan 2024

Wildar Northeast Florida, Kailan Sindelar

UNF Faculty Research and Scholarship

Learn about some of the unique aspects of life in the wetlands and rivers of Northeast Florida and how we study them. In this app players see the memories of a student at the University of North Florida play out in front of them in AR. This app was created with funding the Digital Humanities Institute at the University of North Florida and informed by subject matter experts at the university.


Distal Urogenital Anatomy And Epithelial Morphology In The Male Cajun Chorus Frog, Pseudacris Fouquettei (Anura: Hylidae), S.E. Trauth Jan 2024

Distal Urogenital Anatomy And Epithelial Morphology In The Male Cajun Chorus Frog, Pseudacris Fouquettei (Anura: Hylidae), S.E. Trauth

Journal of the Arkansas Academy of Science

I examined the microanatomy of the distal urogenital system in male Cajun Chorus Frogs (Pseudacris fouquettei) from a small sample (n = 6) collected in central Arkansas in March 2018 and February 2023. Specifically, my primary objectives were to investigate the following: (1) the paired Wolffian (urogenital) ducts caudally from the kidneys to their merging with the urodeum of the cloaca, (2) the structure of seminal vesicles (if present), and (3) the epithelial morphologies among the distal urogenital tract, the posterior alimentary canal, and cloaca. My histological analysis confirmed the presence of ampullae (sperm storage structures) as mid-duct expansions of …


Use Of Google Earth Streetview To Evaluate Nesting By The Cliff Swallow (Petrochelidon Pyrrhonota) In Lowlands Of Eastern Arkansas, With Reports Of New Records, R. Tumlison, Z. Autrey Jan 2024

Use Of Google Earth Streetview To Evaluate Nesting By The Cliff Swallow (Petrochelidon Pyrrhonota) In Lowlands Of Eastern Arkansas, With Reports Of New Records, R. Tumlison, Z. Autrey

Journal of the Arkansas Academy of Science

Cliff Swallows (Petrochelidon pyrrhonota) typically construct their mud nests under the overhangs of cliffs. However, construction of concrete bridges and overpasses has provided suitable nesting structure in the last few decades. As the number of such nesting sites have increased, the breeding range also has expanded. We evaluated the use of Google Earth Streetview as a means of cheaply harvesting data regarding nesting distribution. The gourd-shaped nests of Cliff Swallows were easily discernible via available imagery, and we were able to document previously unreported nest sites of this species in 6 counties in eastern Arkansas (5 from imagery, 1 from …


Shell Damage Patterns In Limpkin Mussel Middens At Bois D’Arc Lake, Arkansas, G.R. Graves Jan 2024

Shell Damage Patterns In Limpkin Mussel Middens At Bois D’Arc Lake, Arkansas, G.R. Graves

Journal of the Arkansas Academy of Science

The Limpkin (Aramus guarauna) is rapidly colonizing the lower Mississippi Valley from recently established Gulf Coast populations. Anecdotal reports indicate that it feeds on freshwater mussels and gastropods in Arkansas, but without documentation. Here I report an analysis of Limpkin shell middens from Bois d’Arc Lake in Hempstead Co. Limpkins at this location preyed heavily on Pyganodon grandis (Giant Floater), a large mussel species widely distributed in the Mississippi Valley. Limpkins employ vigorous bill blows to pierce holes in mussels and usually attack the anterior end of the shell. Video and photographs of feeding birds provide new insight on the …


X-Ray Diffraction And Petrographic Analysis Of Magnet Cove Carbonatite Core, Arkansas, R.E. Mero, D. Mayo, M.P. Testa Jan 2024

X-Ray Diffraction And Petrographic Analysis Of Magnet Cove Carbonatite Core, Arkansas, R.E. Mero, D. Mayo, M.P. Testa

Journal of the Arkansas Academy of Science

Geothermal activity such as hot springs are known to precipitate calcium carbonate (CaCO3) minerals, producing rocks such as tufa, travertine and sometimes associated with carbonatite. The precipitation of CaCO is caused by the reduction of CO, which is less soluble in warmer waters. Geothermal heating of water in natural springs drives this precipitation of CaCO3 in areas of Arkansas including Magnet Cove. Magnet Cove, Arkansas is an alkalic igneous rock complex that is composed of a series of ring dikes post-Mississippian in age. These dikes have intruded into faulted and folded Paleozoic sedimentary rocks. One of these igneous dikes is …


A Strategic Framework For Estimating International Container Flows: An Empirical Study, Dung-Ying Lin, Hsin-Chun Huang, Steven Travis Waller, Xiang Zhang Jan 2024

A Strategic Framework For Estimating International Container Flows: An Empirical Study, Dung-Ying Lin, Hsin-Chun Huang, Steven Travis Waller, Xiang Zhang

Journal of Marine Science and Technology–Taiwan

Maritime transportation is a highly complex transportation system that plays a pivotal role in international trade. Its low-cost and high-volume advantages have enabled it to cover most of the world’s cargo transportation. However, with the trend of global trade volume increasing almost every year and the recent congestion of ports due to the COVID-19 pandemic, the chaos in global supply chains not only increases operating costs for shippers but also makes it difficult for countries that rely heavily on port trade to plan for their ports’ future. To develop a strategic analytic tool to estimate container flow in liner shipping, …


When And Where Can Coastal Wetland Restoration Increase Carbon Sequestration As A Natural Climate Solution, Scott F. Jones, Ariane Arias-Ortiz, Dennis Baldocchi, Meagan Eagle, Daniel A. Friess, Catrina Gore, Greg Noe, Stefanie Nolte, Patty Oikawa, Adina Paytan, Jacqueline L. Raw, Brian J. Roberts, Kerrylee Rogers, Charles Schutte, Camille L. Stagg, Karen M. Thorne, Eric J. Ward, Lisamarie Windham-Myers, Erik S. Yando Jan 2024

When And Where Can Coastal Wetland Restoration Increase Carbon Sequestration As A Natural Climate Solution, Scott F. Jones, Ariane Arias-Ortiz, Dennis Baldocchi, Meagan Eagle, Daniel A. Friess, Catrina Gore, Greg Noe, Stefanie Nolte, Patty Oikawa, Adina Paytan, Jacqueline L. Raw, Brian J. Roberts, Kerrylee Rogers, Charles Schutte, Camille L. Stagg, Karen M. Thorne, Eric J. Ward, Lisamarie Windham-Myers, Erik S. Yando

Biological Sciences Faculty Publications

Coastal wetlands are hotspots of carbon sequestration, and their conservation and restoration can help to mitigate climate change. However, there remains uncertainty on when and where coastal wetland restoration can most effectively act as natural climate solutions (NCS). Here, we synthesize current understanding to illustrate the requirements for coastal wetland restoration to benefit climate, and discuss potential paths forward that address key uncertainties impeding implementation. To be effective as NCS, coastal wetland restoration projects will accrue climate cooling benefits that would not occur without management action (additionality), will be implementable (feasibility) and will persist over management-relevant timeframes (permanence). Several issues …


Cyp6g2 Is The Major P450 Epoxidase Responsible For Juvenile Hormone Biosynthesis In Drosophila Melanogaster, Qiangqiang Jia, Liu Yang, Jiamin Wen, Suning Liu, Di Wen, Wei Luo, Weihua Wang, Subba R. Palli, Li Sheng Jan 2024

Cyp6g2 Is The Major P450 Epoxidase Responsible For Juvenile Hormone Biosynthesis In Drosophila Melanogaster, Qiangqiang Jia, Liu Yang, Jiamin Wen, Suning Liu, Di Wen, Wei Luo, Weihua Wang, Subba R. Palli, Li Sheng

Entomology Faculty Publications

Background Juvenile hormones (JH) play crucial role in regulating development and reproduction in insects. The most common form of JH is JH III, derived from MF through epoxidation by CYP15 enzymes. However, in the higher dipterans, such as the fruitfly, Drosophila melanogaster, a bis-epoxide form of JHB3, accounted most of the JH detected. Moreover, these higher dipterans have lost the CYP15 gene from their genomes. As a result, the identity of the P450 epoxidase in the JH biosynthesis pathway in higher dipterans remains unknown.

Results In this study, we show that Cyp6g2 serves as the major JH epoxidase responsible for …


Endosymbiont Diversity Across Native And Invasive Brown Widow Spider Populations, Monica A. Mowery, Laura Cecilia Rosenwald, Eric G. Chapman, Yael Lubin, Michal Segoli, Thembile Khoza, Robin Lyle, Jennifer A. White Jan 2024

Endosymbiont Diversity Across Native And Invasive Brown Widow Spider Populations, Monica A. Mowery, Laura Cecilia Rosenwald, Eric G. Chapman, Yael Lubin, Michal Segoli, Thembile Khoza, Robin Lyle, Jennifer A. White

Entomology Faculty Publications

The invasive brown widow spider, Latrodectus geometricus (Araneae: Theridiidae), has spread in multiple locations around the world and, along with it, brought associated organisms such as endosymbionts. We investigated endosymbiont diversity and prevalence across putative native and invasive populations of this spider, predicting lower endosymbiont diversity across the invasive range compared to the native range. First, we characterized the microbial community in the putative native (South Africa) and invasive (Israel and the United States) ranges via high throughput 16S sequencing of 103 adult females. All specimens were dominated by reads from only 1–3 amplicon sequence variants (ASV), and most individuals …


Go West: Population Genomics Reveals Unexpected Population Fluctuations And Little Gene Flow In Western Hemisphere Populations Of The Predatory Lady Beetle, Hippodamia Convergens, Arun Sethuraman, Schyler O. Nunziata, Angela Jones, John J. Obrycki, David W. Weisrock Jan 2024

Go West: Population Genomics Reveals Unexpected Population Fluctuations And Little Gene Flow In Western Hemisphere Populations Of The Predatory Lady Beetle, Hippodamia Convergens, Arun Sethuraman, Schyler O. Nunziata, Angela Jones, John J. Obrycki, David W. Weisrock

Entomology Faculty Publications

Hippodamia convergens—the convergent lady beetle, has been used extensively in aug- mentative biological control of aphids, thrips, and whiteflies across its native range in North America, and was introduced into South America in the 1950s. Overwintering H. convergens populations from its native western range in the United States are com- mercially collected and released across its current range in the eastern USA, with little knowledge of the effectiveness of its augmentative biological control. Here we use a novel ddRADseq-based SNP/haplotype discovery approach to estimate its range- wide population diversity, differentiation, and recent evolutionary history. Our results indicate (1) significant population …


N(Alpha)-Acetyltransferase 40-Mediated Histone Acetylation Plays An Important Role In Ecdysone Regulation Of Metamorphosis In The Red Flour Beetle, Tribolium Castaneum, Sharath Chandra Gaddelapati, Smitha George, Anilkumar Moola, Karthi Sengodan, Subba Reddy Palli Jan 2024

N(Alpha)-Acetyltransferase 40-Mediated Histone Acetylation Plays An Important Role In Ecdysone Regulation Of Metamorphosis In The Red Flour Beetle, Tribolium Castaneum, Sharath Chandra Gaddelapati, Smitha George, Anilkumar Moola, Karthi Sengodan, Subba Reddy Palli

Entomology Faculty Publications

Histone acetylation, a crucial epigenetic modification, is governed by histone acetyltransferases (HATs), that regulate many biological processes. Functions of HATs in insects are not well understood. We identified 27 HATs and determined their functions using RNA interference (RNAi) in the model insect, Tribolium castaneum. Among HATs studied, N-alpha-acetyltransferase 40 (NAA40) knockdown caused a severe phenotype of arrested larval development. The steroid hormone, ecdysone induced NAA40 expression through its receptor, EcR (ecdysone receptor). Interestingly, ecdysone-induced NAA40 regulates EcR expression. NAA40 acetylates histone H4 protein, associated with the promoters of ecdysone response genes: EcR, E74, E75, and HR3, and causes an increase …


The Mechanoreceptor Piezo Is Required For Spermatogenesis In Bombyx Mori, Zhongjie Zhang, Xiaojing Liu, Bo Hu, Kai Chen, Ye Yu, Chenxin Sun, Dalin Zhu, Hua Bai, Subba Reddy Palli, Anjiang Tan Jan 2024

The Mechanoreceptor Piezo Is Required For Spermatogenesis In Bombyx Mori, Zhongjie Zhang, Xiaojing Liu, Bo Hu, Kai Chen, Ye Yu, Chenxin Sun, Dalin Zhu, Hua Bai, Subba Reddy Palli, Anjiang Tan

Entomology Faculty Publications

Background The animal sperm shows high diversity in morphology, components, and motility. In the lepidopteran model insect, the silkworm Bombyx mori, two types of sperm, including nucleate fertile eupyrene sperm and anucleate unfertile apyrene sperm, are generated. Apyrene sperm assists fertilization by facilitating the migration of eupyrene spermatozoa from the bursa copulatrix to the spermatheca. During spermatogenesis, eupyrene sperm bundles extrude the cytoplasm by peristaltic squeezing, while the nuclei of the apyrene sperm bundles are discarded with the same process, forming matured sperm.

Results In this study, we describe that a mechanoreceptor BmPiezo, the sole Piezo ortholog in B. mori, …


Tree Species Richness And Ash Density Have Variable Effects On Emerald Ash Borer Biological Control By Woodpeckers And Parasitoid Wasps In Post-Invasion White Ash Stands, Caleb J. Wilson, Toby R. Petrice, Therese M. Poland, Deborah G. Mccullough Jan 2024

Tree Species Richness And Ash Density Have Variable Effects On Emerald Ash Borer Biological Control By Woodpeckers And Parasitoid Wasps In Post-Invasion White Ash Stands, Caleb J. Wilson, Toby R. Petrice, Therese M. Poland, Deborah G. Mccullough

Entomology Faculty Publications

Emerald ash borer (EAB) (Agrilus planipennis Fairmaire) (Coleoptera: Buprestidae) is the most destructive insect to invade North American forests. Identifying habitat features that support EAB natural enemies is necessary to enhance EAB biological control. In many forest ecosystems, tree species diversity has been linked with reduced pest abundance and increases in natural enemy abundance. We assessed the influence of tree species richness, ash density, and proportion of total ash basal area on ash canopy condition, EAB larval densities, and biocontrol by woodpeckers and parasitoids in pairs of healthy and declining overstory (DBH > 10 cm) and recruit-sized ash (DBH 2–10 cm) …


Environmental Implications Of Modern Food Production: An Analysis For The Conscious Consumer, Jessica T. Coming Jan 2024

Environmental Implications Of Modern Food Production: An Analysis For The Conscious Consumer, Jessica T. Coming

Cal Poly Humboldt theses and projects

This project explores the pathways by which agriculture affects the environment and determines which foods have the greatest climate, water, and land impacts. Agricultural effects on the environment are extensive, from loss of habitat and declines in regional biodiversity to disruption of global nutrient cycles and climate change. Global food production accounts for 26-34% of annual anthropogenic greenhouse gas emissions, makes up 38-46% of habitable land, and is responsible for 70% of freshwater extraction. The effect of agriculture on the environment is most significantly dictated by what type of food is being produced. Animal-based food products consistently have the highest …


Informing Standardized Wood Turtle (Glyptemys Insculpta) Population Monitoring: Influences Of Sampling Approach And Turtle Behavior On Model Estimation, Allyson N. Beard Jan 2024

Informing Standardized Wood Turtle (Glyptemys Insculpta) Population Monitoring: Influences Of Sampling Approach And Turtle Behavior On Model Estimation, Allyson N. Beard

Graduate Theses, Dissertations, and Problem Reports (ETD)

To better understand wood turtle (Glyptemys insculpta) population trends, two standardized population survey protocols were recently developed for use by state monitoring programs. The protocols were independently developed, tested, and deployed for population monitoring in the eastern and upper midwestern United States. It was unknown if the sampling designs result in similar detection success or if data from the two protocols are compatible for broad-scale analyses. Additionally, neither monitoring protocol includes a sampling design that allows for the separation of detection (p) into availability (pa), and detection given availability (pd). …


Traumatic Brain Injury Induces Cerebrovascular Dysfunction: Consequences For Ischemia And Cerebral Hypoperfusion, Bailey J. Whitehead Jan 2024

Traumatic Brain Injury Induces Cerebrovascular Dysfunction: Consequences For Ischemia And Cerebral Hypoperfusion, Bailey J. Whitehead

Graduate Theses, Dissertations, and Problem Reports (ETD)

Traumatic brain injury (TBI) is a significant health concern across the United States as well as the broader globe, affecting millions of individuals on an annual basis. While most recover from their TBI and resume their lives normally, some subsets of TBI survivors continue to experience impairments and increased risk for future diseases like cardiovascular disease, stroke, and aging related disease like Alzheimer’s Disease or VCID.

TBI remains a fundamentally difficult neurological injury to pin down mechanistically, due to the variability in severity, timing, and age of patient, among other factors. One significant factor in the pathology has consistently been …


Cell-Type-Specific Effects Of Synaptic Zinc In Mouse Auditory Cortex, Mason Mccollum Jan 2024

Cell-Type-Specific Effects Of Synaptic Zinc In Mouse Auditory Cortex, Mason Mccollum

Graduate Theses, Dissertations, and Problem Reports (ETD)

Synaptic zinc signaling modulates synaptic activity and is present in specific populations of cortical neurons, suggesting that synaptic zinc contributes to the diversity of intracortical synaptic microcircuits and their auditory tuning properties. Stimulus-specific adaptation is a hallmark of sensory processing in which a repeated stimulus results in diminished successive neuronal responses, but a deviant stimulus will still elicit robust responses from the same neurons. Recent work has established that synaptically released zinc is an endogenous mechanism that shapes neuronal responses to sounds in the auditory cortex. Here, to understand the role of zinc signaling in the auditory cortex and the …


Estimating Steelhead Smolt Abundance From A Mixed Resident/Anadromous Oncorhynchus Mykiss Population, Gabriel Temple Jan 2024

Estimating Steelhead Smolt Abundance From A Mixed Resident/Anadromous Oncorhynchus Mykiss Population, Gabriel Temple

All Master's Theses

Effective management of fish populations in inland waters requires, at the most fundamental level, a basic understanding of population abundance. This is especially important for critically depressed species having high conservation value. Unfortunately, due to their critically depressed abundance, the anadromous form of Oncorhynchus mykiss, known as Steelhead Trout, has high conservation value in the upper Yakima Basin located in central Washington State. However, the resident form of O. mykiss, known as Rainbow Trout, are numerous in the watershed. We used a juvenile tagging study coupled with a long-term population monitoring study to disaggregate this mixed O. mykiss …


Factors Associated With The Prevalence Of Iron Deficiency And Anemia In Women Of Reproductive Age In The U.S.: Nhanes 2015-2020, Catherine Wise Jan 2024

Factors Associated With The Prevalence Of Iron Deficiency And Anemia In Women Of Reproductive Age In The U.S.: Nhanes 2015-2020, Catherine Wise

All Master's Theses

Iron deficiency (ID) is well recognized as the most prevalent nutrient insufficiency and a leading cause of anemia. Women of reproductive age (WRA), females 15 to 49, are at an increased risk of ID and anemia. This is due to the heightened iron demands of this life stage, including puberty, menstruation, and pregnancy, which require iron intakes ranging from 15 to 27 mg/day. Poor health and nutrition increase the risk of ID and progression to anemia. Consequences of ID and anemia range from exhaustion and decreased cognitive function to an increased risk of mortality. This study aimed to assess the …


Investigating A Potential Protein-Protein Interaction Between Transcription Factor Pax6 And Ribosomal Protein S20 (Rps20), Modupe Oladayo Jan 2024

Investigating A Potential Protein-Protein Interaction Between Transcription Factor Pax6 And Ribosomal Protein S20 (Rps20), Modupe Oladayo

All Master's Theses

The neocortex is the largest region of mammalian brains and is responsible for the complex cognitive abilities and behaviors of mammals. The neocortex of mature mammals is divided into concise areas, which process sensory information from ears, eyes, and touch receptors, and regulate conscious movement of muscles. The combined graded expressions of several transcription factors over the embryonic neocortical ventricular zone regulates the sizes of these functional areas in the adult neocortex. Although progress has been made in understanding how transcription factors affect neocortical patterning, additional research is required to fully understand the underlying molecular mechanism(s), which will contribute to …


Comparing The Prevalence Of Stereotypic Behaviors And Enrichment Use In Rhesus (Macaca Mulatta) And Japanese Macaques (M. Fuscata), Jesscia Oscavich Jan 2024

Comparing The Prevalence Of Stereotypic Behaviors And Enrichment Use In Rhesus (Macaca Mulatta) And Japanese Macaques (M. Fuscata), Jesscia Oscavich

All Master's Theses

To improve captive nonhuman primates’ welfare, particularly those utilized in biomedical and behavioral research, it’s important to understand their behavior. Rhesus (Macaca mulatta) and Japanese macaques (M. fuscata) are two closely related species that are commonly utilized in biomedical and behavioral research. In this study, I compared the frequency of stereotypic behaviors, which are abnormal repetitive behaviors that are apparently non-functional, and enrichment use among four groups of each species. Stereotypic behaviors were divided into motor, which the animal performed while active, and self-directed stereotypies, which the animal performed towards themselves. Enrichment use was divided into …


Prenatal Androgen Exposure Reduces Ovarian Function, Marlee Weets Jan 2024

Prenatal Androgen Exposure Reduces Ovarian Function, Marlee Weets

All Master's Theses

Polycystic ovary syndrome (PCOS) is the most common reproductive and endocrine disorder, being the leading cause of infertility for females of reproductive age. The etiology of PCOS is not fully known, although it is hypothesized that there is a genetic, epigenetic, and environmental component to the disease. One of the environmental influences that can cause an abnormal reproductive phenotype similar to PCOS is prenatal exposure to excess androgens (male sex hormones). Previous studies have shown that prenatal exposure to androgens in mice can cause a PCOS-like ovarian phenotype similar to people with PCOS. To examine how prenatal androgen exposure causes …


The Auricular Surface Of Chimpanzees (Pan Troglodytes) As An Indicator Of Age, Kalila Garrison Jan 2024

The Auricular Surface Of Chimpanzees (Pan Troglodytes) As An Indicator Of Age, Kalila Garrison

All Master's Theses

Great ape skeletal remains are scarce and their use in biological profile estimations has been limited. Skeletal remains analysis provides key demographic information and ecological context to the individual. Chimpanzees (Pan troglodytes) share skeletal morphological characteristics with humans, and this study seeks to understand if two noninvasive methods using the auricular surface of the ilium to age human skeletal remains could be applied to chimpanzees. The sample consisted of n = 8 individual left auricular surfaces from known age groups of both sexes. Firstly, the Buckberry and Chamberlain Method assigns numerical values to five different traits on the auricular …


Objective Assessment Of Shared Plate Eating Using A Wearable Camera In Urban And Rural Households In Ghana, Christabel A Domfe, Megan A Mccrory, Edward Sazonov, Tonmoy Ghosh, Viprav Raju, Gary Frost, Matilda Steiner-Asiedu, Mingui Sun, Wenyan Jia, Tom Baranowski, Benny Lo, Alex K Anderson Jan 2024

Objective Assessment Of Shared Plate Eating Using A Wearable Camera In Urban And Rural Households In Ghana, Christabel A Domfe, Megan A Mccrory, Edward Sazonov, Tonmoy Ghosh, Viprav Raju, Gary Frost, Matilda Steiner-Asiedu, Mingui Sun, Wenyan Jia, Tom Baranowski, Benny Lo, Alex K Anderson

Children’s Nutrition Research Center Staff Publications

Background: Shared plate eating (SPE), defined as two or more individuals eating directly from the same plate or bowl, is a common household food consumption practice in many Low- and Middle-Income Countries (LMICs). Examination of household engagement in SPE remains largely unexplored, highlighting a gap in research when interpreting dietary information obtained from these settings. The dearth of research into SPE can be attributed to the inherent limitations of traditional dietary assessment methods which constrain their usability in settings where SPE is common.

Objective: In this expository narrative, we describe what SPE is when it is practiced in an LMIC …


Novel, Pathogenic Insertion Variant Of Gsdme Associates With Autosomal Dominant Hearing Loss In A Large Chinese Pedigree, Jingliang Cheng, Ting Li, Qi Tan, Jiewen Fu, Lianmei Zhang, Luquan Yang, Baixu Zhou, Lisha Yang, Shangyi Fu, Alora Grace Linehan, Junjiang Fu Jan 2024

Novel, Pathogenic Insertion Variant Of Gsdme Associates With Autosomal Dominant Hearing Loss In A Large Chinese Pedigree, Jingliang Cheng, Ting Li, Qi Tan, Jiewen Fu, Lianmei Zhang, Luquan Yang, Baixu Zhou, Lisha Yang, Shangyi Fu, Alora Grace Linehan, Junjiang Fu

Children’s Nutrition Research Center Staff Publications

Nonsyndromic hearing loss (NSHL) is a genetically diverse, highly heterogeneous condition characterised by deafness, and Gasdermin E (GSDME) variants have been identified as directly inducing autosomal dominant NSHL. While many NSHL cases associated with GSDME involve the skipping of exon 8, there is another, less understood pathogenic insertion variant specifically found in Chinese pedigrees that causes deafness, known as autosomal dominant 5 (DFNA5) hearing loss. In this study, we recruited a large Chinese pedigree, conducted whole‐exome and Sanger sequencing to serve as a comprehensive clinical examination, and extracted genomic DNA samples for co‐segregation analysis of the members. Conservation …


Combinatorial Atoh1, Gfi1, Pou4f3, And Six1 Gene Transfer Induces Hair Cell Regeneration In The Flat Epithelium Of Mature Guinea Pigs, Yujie Liu, Lin Yang, Sunita Singh, Lisa A Beyer, Diane M Prieskorn, Donald L Swiderski, Andrew K Groves, Yehoash Raphael Jan 2024

Combinatorial Atoh1, Gfi1, Pou4f3, And Six1 Gene Transfer Induces Hair Cell Regeneration In The Flat Epithelium Of Mature Guinea Pigs, Yujie Liu, Lin Yang, Sunita Singh, Lisa A Beyer, Diane M Prieskorn, Donald L Swiderski, Andrew K Groves, Yehoash Raphael

Children’s Nutrition Research Center Staff Publications

Flat epithelium (FE) is a condition characterized by the loss of both hair cells (HCs) and supporting cells and the transformation of the organ of Corti into a simple flat or cuboidal epithelium, which can occur after severe cochlear insults. The transcription factors Gfi1, Atoh1, Pou4f3, and Six1 (GAPS) play key roles in HC differentiation and survival in normal ears. Previous work using a single transcription factor, Atoh1, to induce HC regeneration in mature ears in vivo usually produced very few cells and failed to produce HCs in severely damaged organs of Corti, especially those with FE. Studies in vitro …