Open Access. Powered by Scholars. Published by Universities.®

Life Sciences Commons™

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 28981 - 29010 of 255945

Full-Text Articles in Life Sciences

The Plants Database: Providing Basic Plant Information, J S. Peterson, J F. Henson, W Oaks, J T. Kartesz Feb 2024

The Plants Database: Providing Basic Plant Information, J S. Peterson, J F. Henson, W Oaks, J T. Kartesz

IGC Proceedings (1977-2023)

The PLANTS database provides basic plant information to the United States Department of Agriculture (USDA), Natural Resources Conservation Service (NRCS), its clients, cooperators, and the general public via the World Wide Web (Fig. 1). The foundation of PLANTS is a taxonomic backbone (checklist) of the vascular and nonvascular plants of North America (north of Mexico) and United States territories in the Caribbean and Pacific regions. Attribute data are appended to this backbone pertaining to distribution, vegetative specifications, nativity, federal and state status, crop data, growth form, growth parameters, species abstracts, and images.


Forage Production Potential Of Poa Arachnifera Torr In Semi-Arid Climates, J C. Read, M A. Sanderson, G W. Evers, P W. Voigt, J A. Reinert Feb 2024

Forage Production Potential Of Poa Arachnifera Torr In Semi-Arid Climates, J C. Read, M A. Sanderson, G W. Evers, P W. Voigt, J A. Reinert

IGC Proceedings (1977-2023)

This study was undertaken to determine the forage potential of Texas bluegrass (Poa arachnifera Torr). Texas bluegrass is a perennial coolseason grass native to Kansas, Oklahoma, western Arkansas, and the central region of Texas, USA (Gould, 1975). Thirteen different accessions were established in 1988 at the Texas A&M University Centers at Dallas and Stephenville and tested for 2 years. Mean yields at Stephenville and Dallas were 3610 and 6022 kg ha-1. Two synthetic varieties (Syn-1 and Syn-2) were tested from 1990 to 1995 at four locations in Texas. Yields of Syn-1 was greater than Syn-2 whereas Syn- 2 provided …


More Aeschynomene Pasture Legumes For The Tropics And Sub-Tropics, H G. Bishop, B G. Cook, B H. English, J J. Bushell, T B. Hilder Feb 2024

More Aeschynomene Pasture Legumes For The Tropics And Sub-Tropics, H G. Bishop, B G. Cook, B H. English, J J. Bushell, T B. Hilder

IGC Proceedings (1977-2023)

Two cultivars of Aeschynomene villosa were released in Queensland in 1995. Cultivars ‘Reid’ (previously CPI 91209) and ‘Kretschmer’ (previously CPI 93621) are both native to Mexico and are the first cultivars of A. villosa to be released as pasture legumes. They will complement the three Aeschynomene cultivars already in use in tropical and sub-tropical northern and eastern Australia, namely cultivars ‘Glenn’ and ‘Lee’ (A. americana) and ‘Bargoo’ (A. falcata). Characteristics of Reid and Kretschmer jointvetch include, early seeding perennials within high seed yields, prostrate to semi-erect growth habit, adaptation to a wide range of soil types …


Integrating Cannabis Education Into The Athletic Training Curriculum, Jeff G. Konin, Jimmy Onate Feb 2024

Integrating Cannabis Education Into The Athletic Training Curriculum, Jeff G. Konin, Jimmy Onate

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Context. Cannabis has become more prevalent in society and requires greater knowledge on the part of the athletic trainer. Objective. The purpose of this paper is to provide a framework for recognizing how cannabis education can be integrated into the athletic training curriculum utilizing the existing accreditation standards. Background. For decades the use of cannabis has been illegal. Athletes who were caught with cannabis in their system were penalized by their respective e sport organization body. During the past decade in the United States the federal government has moved toward decriminalization and expungement for those found with and …


Breaking Barriers And Building Confidence: Interprofessional Education's Impact On Allied Health Students' Competence And Self-Efficacy In Addressing Exercise Accessibility For People With Disabilities, Elizabeth A. Starns, Rebecca Wehler, Lindsay A. Church, Stephanie Kubiak Feb 2024

Breaking Barriers And Building Confidence: Interprofessional Education's Impact On Allied Health Students' Competence And Self-Efficacy In Addressing Exercise Accessibility For People With Disabilities, Elizabeth A. Starns, Rebecca Wehler, Lindsay A. Church, Stephanie Kubiak

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: The researchers’ objective was to evaluate the effectiveness of an interprofessional educational (IPE) program on student learning while addressing exercise accessibility barriers experienced by people living with disabilities (PLWD), including allied health professionals’ lack of practical experience, knowledge, and perceived competence and comfort working with PLWD in a fitness setting. Method: A qualitative explanatory single case study approach utilizing individual interviews was used. The individual interviews that explored how a collaboration between allied health students influenced learning, perceived comfort, and perceived competence working with PLWD were audio-recorded, transcribed verbatim and thematically analyzed. Results: Four major themes emerged: collaboration, comfort, …


Athletic Trainers’ Stress, Support, And External Pressures When Making Clinical Decisions, Stephanie Carr, Meredith Madden, Meredith Kneavel, Tom Bowman Feb 2024

Athletic Trainers’ Stress, Support, And External Pressures When Making Clinical Decisions, Stephanie Carr, Meredith Madden, Meredith Kneavel, Tom Bowman

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Context: Athletic trainers (ATs) work in various settings with very different work environments and patient populations. How stress, social and organizational support, and external pressures alter athletic training decision-making remains unknown. Objective: Determine the relationship between workplace stress, social support, and organizational support for ATs who are providing healthcare. Design: Concurrent mixed methods. Setting: Online survey. Patients or Other Participants: 275 (7% response rate; 76 females, 44 males, 1 third gender/self-identify, 154 wished not to disclose; age=36.80±11.9 years, experience =13.65±12.55 years) athletic trainers. Interventions: The size (SSQ-N) and quality (SSQ-Q) components of the social support scale (SSQ) and the …


In Memoriam Richard F. Ayrey (1948 – 2024), Melinda Deboer-Ayrey, Brandon T. Myers, Robert W. Bryson, Jr., Michael M. Webber, Matthew R. Graham, Graeme Lowe, Victor Fet, František Kovařík Feb 2024

In Memoriam Richard F. Ayrey (1948 – 2024), Melinda Deboer-Ayrey, Brandon T. Myers, Robert W. Bryson, Jr., Michael M. Webber, Matthew R. Graham, Graeme Lowe, Victor Fet, František Kovařík

Euscorpius

This is a memorial issue honoring Richard F. Ayrey (1948 – 2024), a US scorpiologist. A full list of his 26 works is appended, as well as a list of scorpion taxa described by Richard (two genera and 19 species of Vaejovidae), and a map of their type localities in the USA and Mexico.


Dimensionality Reduction: Principal Component Analysis Of Workload Of An Nba Game, Brian Audelio Serrano Feb 2024

Dimensionality Reduction: Principal Component Analysis Of Workload Of An Nba Game, Brian Audelio Serrano

Doctoral Dissertations and Projects

The worlds of sports science, data analytics, and sports performance are at a crossroads. Each field is accustomed to functioning in relative silos; however, this approach is quickly becoming outdated. Sporting organizations are adopting high-performance models that integrate all departments and their subsequent data pipelines. This has led to a wealth of information not available before to a team’s performance health staff in guiding optimal athletic performance. Within the sport of basketball, these silos can be split further into video coaching, basketball analytics, sports science, player development, and performance health. Specifically, basketball sports science can be categorized into internal and …


Managing Saline And Sodic Soils And Irrigation Water, Burdette Barker, Grant Cardon, Matt Yost, Melanie Stock, Earl Creech, Jody Gale Feb 2024

Managing Saline And Sodic Soils And Irrigation Water, Burdette Barker, Grant Cardon, Matt Yost, Melanie Stock, Earl Creech, Jody Gale

All Current Publications

Salt is an important factor in plant and soil management. Excessive salt concentrations in soil can cause water to be less available to plants because of the osmotic forces of salt in the soil water. Excessive concentrations of different ions can also be toxic to plants. In agricultural soils and irrigation water, salts are typically described in two ways: (1) total salt concentration or salinity, and (2) sodicity, or the concentration of sodium relative to other cations (positively charged atoms or compounds). Understanding the effect of both total salinity and sodicity on plants and soils, along with management and reclamation …


Livestock Risk Protection Insurance: Feeder Cattle, Logan B. Haviland, Ryan Feuz Feb 2024

Livestock Risk Protection Insurance: Feeder Cattle, Logan B. Haviland, Ryan Feuz

All Current Publications

Livestock risk protection (LRP) insurance is a partially subsidized livestock insurance provided by the United States Department of Agriculture (USDA) Risk Management Agency (RMA) that provides protection to producers against unexpected price declines. This fact sheet presents specific coverage information for feeder cattle and presents optimal coverage options based on historical contract performance.


Livestock Risk Protection Insurance: Swine, Logan B. Haviland, Ryan Feuz Feb 2024

Livestock Risk Protection Insurance: Swine, Logan B. Haviland, Ryan Feuz

All Current Publications

Livestock risk protection (LRP) insurance is a partially subsidized livestock insurance provided by the United States Department of Agriculture (USDA) Risk Management Agency (RMA) that provides protection to producers against unexpected price declines. This fact sheet presents specific coverage information for swine and presents optimal coverage options based on historical contract performance.


Livestock Risk Protection Insurance: Fed Cattle, Logan B. Haviland, Ryan Feuz Feb 2024

Livestock Risk Protection Insurance: Fed Cattle, Logan B. Haviland, Ryan Feuz

All Current Publications

Livestock risk protection (LRP) insurance is a partially subsidized livestock insurance provided by the United States Department of Agriculture (USDA) Risk Management Agency (RMA) that provides protection to producers against unexpected price declines. This fact sheet presents specific coverage information for fed cattle and presents optimal coverage options based on historical contract performance.


Toxicity And Risk Of Biopesticides To Insect Pollinators In Urban And Agricultural Landscapes, Joshua Chavana, Neelendra K. Joshi Feb 2024

Toxicity And Risk Of Biopesticides To Insect Pollinators In Urban And Agricultural Landscapes, Joshua Chavana, Neelendra K. Joshi

Entomology Faculty Publications and Presentations

Pollinators play important roles in providing pollination services, maintaining biodiversity, and boosting crop production. Even though pollinators are essential to the environment and agriculture, their decline has been noted across multiple studies in the recent past. Both natural and anthropogenic factors have contributed to their decline. Much of the focus has been placed on climate change, habitat loss, pests and pathogens, and synthetic pesticides, but relatively little is known about the effects of biopesticides. Biopesticides are biological control agents derived from living organisms and are classified into three groups: microbial, biochemical, and plant-incorporated protectant-based products. Biopesticides are formulated similarly to …


Biological Insights From Plasma Proteomics Of Non-Small Cell Lung Cancer Patients Treated With Immunotherapy, Jair Bar, Raya Leibowitz, Niels Reinmuth, Astrid Ammendola, Eyal Jacob, Mor Moskovitz, Adva Levy-Barda, Michal Lotem, Rivka Katsenelson, Abed Agbarya, Mahmoud Abu-Amna, Maya Gottfried, Tatiana Harkovsky, Ido Wolf, Ella Tepper, Gil Loewenthal, Ben Yellin, Yehuda Brody, Nili Dahan, Maya Yanko, Coren Lahav, Michal Harel, Shani Raveh Shoval, Yehonatan Elon, Itamar Sela, Adam Dicker, Yuval Shaked Feb 2024

Biological Insights From Plasma Proteomics Of Non-Small Cell Lung Cancer Patients Treated With Immunotherapy, Jair Bar, Raya Leibowitz, Niels Reinmuth, Astrid Ammendola, Eyal Jacob, Mor Moskovitz, Adva Levy-Barda, Michal Lotem, Rivka Katsenelson, Abed Agbarya, Mahmoud Abu-Amna, Maya Gottfried, Tatiana Harkovsky, Ido Wolf, Ella Tepper, Gil Loewenthal, Ben Yellin, Yehuda Brody, Nili Dahan, Maya Yanko, Coren Lahav, Michal Harel, Shani Raveh Shoval, Yehonatan Elon, Itamar Sela, Adam Dicker, Yuval Shaked

Department of Radiation Oncology Faculty Papers

INTRODUCTION: Immune checkpoint inhibitors have made a paradigm shift in the treatment of non-small cell lung cancer (NSCLC). However, clinical response varies widely and robust predictive biomarkers for patient stratification are lacking. Here, we characterize early on-treatment proteomic changes in blood plasma to gain a better understanding of treatment response and resistance.

METHODS: Pre-treatment (T0) and on-treatment (T1) plasma samples were collected from 225 NSCLC patients receiving PD-1/PD-L1 inhibitor-based regimens. Plasma was profiled using aptamer-based technology to quantify approximately 7000 plasma proteins per sample. Proteins displaying significant fold changes (T1:T0) were analyzed further to identify associations with clinical outcomes using …


Livestock Risk Protection Insurance Faq, Logan B. Haviland, Ryan Feuz Feb 2024

Livestock Risk Protection Insurance Faq, Logan B. Haviland, Ryan Feuz

All Current Publications

Livestock risk protection (LRP) insurance is a partially subsidized livestock insurance provided by the United States Department of Agriculture (USDA) Risk Management Agency (RMA) that provides protection to producers against unexpected price declines. This fact sheet presents commonly asked questions and answers surrounding livestock risk protection insurance. It outlines the purpose of the program and explains how producers can use LRP insurance to mitigate price risk.


Efficacy Of Powdered Alfalfa Leaves To Ameliorate The Toxic Effects Of Aflatoxin B1 In Turkey Poults, M.J. Nava-Ramírez, Jesus A. Maguey-Gonzalez, S. Gomez-Rosales, J. O. Hernandez-Ramirez, Juan D. Latorre, Xiangwei Du, C. Lopez-Coello, Billy Hargis, G. Tellez-Isaias, A. Vasquez-Duran, A. Mendez-Albores Feb 2024

Efficacy Of Powdered Alfalfa Leaves To Ameliorate The Toxic Effects Of Aflatoxin B1 In Turkey Poults, M.J. Nava-Ramírez, Jesus A. Maguey-Gonzalez, S. Gomez-Rosales, J. O. Hernandez-Ramirez, Juan D. Latorre, Xiangwei Du, C. Lopez-Coello, Billy Hargis, G. Tellez-Isaias, A. Vasquez-Duran, A. Mendez-Albores

Poultry Science Faculty Publications and Presentations

Abstract

This experiment was conducted to determine the effect of an adsorbent material based on powdered alfalfa leaves added in the aflatoxin B1 (AFB1)-contaminated diet of turkey poults on production parameters, blood cell count, serum biochemistry, liver enzymes, and liver histology. For this purpose, three hundred and fifty female Nicholas-700 poults were randomly assigned into five treatments: (1) Control, AFB1-free diet; (2) AF, diet contaminated with 250 ng AFB1/g; (3) Alfalfa, AFB1-free diet + 0.5% (w/w) adsorbent; (4) AF+alfalfa, diet contaminated with 250 ng AFB1/g + 0.5% (w/w) adsorbent, …


Raw Nmr Data For Tripeptides, David J. Michaelis, Scott R. Burt, Mariur Rodriguez Moreno, Nye C. Johnson, Christopher B. Stewart, Mary L. Setelin, Adam X. Wayment, Braxton M. Felix Feb 2024

Raw Nmr Data For Tripeptides, David J. Michaelis, Scott R. Burt, Mariur Rodriguez Moreno, Nye C. Johnson, Christopher B. Stewart, Mary L. Setelin, Adam X. Wayment, Braxton M. Felix

ScholarsArchive Data

This data set contains primary data for 50 tripeptides that were generated as part of an advanced undergraduate laboratory experience in solid phase peptide synthesis. The raw data can be processed sing NMR interpretation software and can be used as problems for exams and quizzes or as supplementary materials for a laboratory experience


Cook2024_Influence Of Planting Depth Data, Kyle A. Cook, Brad Geary, Phil S. Allen, April Hulet, Kevin Gunnell, Melissa Landeen, Shannon V. Nelson, Matthew D. Madsen Feb 2024

Cook2024_Influence Of Planting Depth Data, Kyle A. Cook, Brad Geary, Phil S. Allen, April Hulet, Kevin Gunnell, Melissa Landeen, Shannon V. Nelson, Matthew D. Madsen

ScholarsArchive Data

This file contains the data description for the Cook2024_1_Influence of Planting Depth… Supplementary File.

The excel file contains two worksheets: 1) Lab Trial Data, and 2) Field Trial Data.

1) Lab Trial Data

A) Block: block (rep) of the sample

B) Soil Type: soil type for that sample- loam, sandy-loam, or loamy-sand

C) Seed Treatment: seed treatment, control or coated

D) Seeding Depth (mm): depth, in mm, the seeds were planted- 0, 3.2, 6.3, 12.7

E) Week 1 Emerge: total number of seedlings emerged in Week 1

F) Week 2 Emerge: total number of seedlings emerged in Week 2 (includes …


Bermad: Batch Effect Removal For Single-Cell Rna-Seq Data Using A Multi-Layer Adaptation Autoencoder With Dual-Channel Framework, Xiangxin Zhan, Yanbin Yin, Han Zhang Feb 2024

Bermad: Batch Effect Removal For Single-Cell Rna-Seq Data Using A Multi-Layer Adaptation Autoencoder With Dual-Channel Framework, Xiangxin Zhan, Yanbin Yin, Han Zhang

Department of Food Science and Technology: Faculty Publications

Motivation: Removal of batch effect between multiple datasets from different experimental platforms has become an urgent problem, since single-cell RNA sequencing (scRNA-seq) techniques developed rapidly. Although there have been some methods for this problem, most of them still face the challenge of under-correction or over-correction. Specifically, handling batch effect in highly nonlinear scRNA-seq data requires a more powerful model to address under-correction. In the meantime, some previous methods focus too much on removing difference between batches, which may disturb the biological signal heterogeneity of datasets generated from different experiments, thereby leading to over-correction.

Results: In this article, we …


Pan-Cancer Proteogenomics Characterization Of Tumor Immunity, Francesca Petralia, Weiping Ma, Tomer M Yaron, Francesca Pia Caruso, Nicole Tignor, Daniel Charytonowicz, Emily M Huntsman, Giacomo B Marino, Anna Calinawan, John Erol Evangelista, Myvizhi Esai Selvan, Shrabanti Chowdhury, Dmitry Rykunov, Azra Krek, Xiaoyu Song, Berk Turhan, Karen E Christianson, David A Lewis, Eden Z Deng, Daniel J B Clarke, Jeffrey R Whiteaker, Jacob J Kennedy, Lei Zhao, Rossana Lazcano Segura, Harsh Batra, Maria Gabriela Raso, Edwin Roger Parra, Rama Soundararajan, Ximing Tang, Yize Li, Xinpei Yi, Shankha Satpathy, Ying Wang, Maciej Wiznerowicz, Tania J González-Robles, Antonio Iavarone, Sara J C Gosline, Boris Reva, Ana I Robles, Alexey I Nesvizhskii, D R Mani, Michael A Gillette, Robert J Klein, Marcin Cieslik, Bing Zhang, Amanda G Paulovich, Robert Sebra, Zeynep H Gümüş, Galen Hostetter, David Fenyö, Gilbert S Omenn, Lewis C Cantley, Avi Ma'ayan, Alexander J Lazar, Michele Ceccarelli, Pei Wang, Clinical Proteomic Tumor Analysis Consortium Feb 2024

Pan-Cancer Proteogenomics Characterization Of Tumor Immunity, Francesca Petralia, Weiping Ma, Tomer M Yaron, Francesca Pia Caruso, Nicole Tignor, Daniel Charytonowicz, Emily M Huntsman, Giacomo B Marino, Anna Calinawan, John Erol Evangelista, Myvizhi Esai Selvan, Shrabanti Chowdhury, Dmitry Rykunov, Azra Krek, Xiaoyu Song, Berk Turhan, Karen E Christianson, David A Lewis, Eden Z Deng, Daniel J B Clarke, Jeffrey R Whiteaker, Jacob J Kennedy, Lei Zhao, Rossana Lazcano Segura, Harsh Batra, Maria Gabriela Raso, Edwin Roger Parra, Rama Soundararajan, Ximing Tang, Yize Li, Xinpei Yi, Shankha Satpathy, Ying Wang, Maciej Wiznerowicz, Tania J González-Robles, Antonio Iavarone, Sara J C Gosline, Boris Reva, Ana I Robles, Alexey I Nesvizhskii, D R Mani, Michael A Gillette, Robert J Klein, Marcin Cieslik, Bing Zhang, Amanda G Paulovich, Robert Sebra, Zeynep H Gümüş, Galen Hostetter, David Fenyö, Gilbert S Omenn, Lewis C Cantley, Avi Ma'ayan, Alexander J Lazar, Michele Ceccarelli, Pei Wang, Clinical Proteomic Tumor Analysis Consortium

Faculty, Staff and Student Publications

Despite the successes of immunotherapy in cancer treatment over recent decades, less than <10%-20% cancer cases have demonstrated durable responses from immune checkpoint blockade. To enhance the efficacy of immunotherapies, combination therapies suppressing multiple immune evasion mechanisms are increasingly contemplated. To better understand immune cell surveillance and diverse immune evasion responses in tumor tissues, we comprehensively characterized the immune landscape of more than 1,000 tumors across ten different cancers using CPTAC pan-cancer proteogenomic data. We identified seven distinct immune subtypes based on integrative learning of cell type compositions and pathway activities. We then thoroughly categorized unique genomic, epigenetic, transcriptomic, and proteomic changes associated with each subtype. Further leveraging the deep phosphoproteomic data, we studied kinase activities in different immune subtypes, which revealed potential subtype-specific therapeutic targets. Insights from this work will facilitate the development of future immunotherapy strategies and enhance precision targeting with existing agents.


Mechanisms Of Sleep Disturbances In Long-Term Cancer Survivors: A Childhood Cancer Survivor Study Report, Lauren C Daniel, Huiqi Wang, Tara M Brinkman, Kathy Ruble, Eric S Zhou, Robyn Stremler, Daniel A Mulrooney, Valerie M Crabtree, Sogol Mostoufi-Moab, Kevin Oeffinger, Joseph Neglia, Yutaka Yasui, Gregory T Armstrong, Kevin Krull Feb 2024

Mechanisms Of Sleep Disturbances In Long-Term Cancer Survivors: A Childhood Cancer Survivor Study Report, Lauren C Daniel, Huiqi Wang, Tara M Brinkman, Kathy Ruble, Eric S Zhou, Robyn Stremler, Daniel A Mulrooney, Valerie M Crabtree, Sogol Mostoufi-Moab, Kevin Oeffinger, Joseph Neglia, Yutaka Yasui, Gregory T Armstrong, Kevin Krull

Faculty, Staff and Student Publications

Background: Sleep problems following childhood cancer treatment may persist into adulthood, exacerbating cancer-related late effects and putting survivors at risk for poor physical and psychosocial functioning. This study examines sleep in long-term survivors and their siblings to identify risk factors and disease correlates.

Methods: Childhood cancer survivors (≥5 years from diagnosis; n = 12 340; 51.5% female; mean [SD] age = 39.4 [9.6] years) and siblings (n = 2395; 57.1% female; age = 44.6 [10.5] years) participating in the Childhood Cancer Survivor Study completed the Pittsburgh Sleep Quality Index (PSQI). Multivariable Poisson-error generalized estimating equation compared prevalence of binary sleep …


Vkorc1 Polymorphisms And Complete Resistance To Vitamin K Antagonists: About Two Cases., Ilham Benyamna, Houda El Fissi, Fadoua Bouzid, Abdelhamid El Mousadik, Najat Alif Feb 2024

Vkorc1 Polymorphisms And Complete Resistance To Vitamin K Antagonists: About Two Cases., Ilham Benyamna, Houda El Fissi, Fadoua Bouzid, Abdelhamid El Mousadik, Najat Alif

BioMedicine

Complete resistance to vitamin K antagonists is a rare but serious. It can complicate therapeutic management, especially when direct oral anticoagulants cannot be used. Some single mutations in the VKORC1 gene have been identified in patients partially or completely resistant to vitamin K antagonists. We report the cases of two women in their fifties who presented an unexplained peripheral venous thrombosis. The aetiological assessment did not show any abnormalities. Genetic testing showed that both patients had the VKORC1 5417GG genotype. The VKORC1 3673 genotype was GG in case 1 and GA in case 2. The two patients showed complete resistance …


Computational Analysis Of Dimer G6pd Structure To Elucidate Pathogenicity Of G6pd Variants, Shamini Chandran, Naveen Eugene Louis, Syazwani Itri Amran, Nurriza Ab Latif, Muaawia Ahmed Hamza, Mona Alonazi Feb 2024

Computational Analysis Of Dimer G6pd Structure To Elucidate Pathogenicity Of G6pd Variants, Shamini Chandran, Naveen Eugene Louis, Syazwani Itri Amran, Nurriza Ab Latif, Muaawia Ahmed Hamza, Mona Alonazi

BioMedicine

An inherent genetic enzyme disorder in humans, known as glucose-6-phosphate dehydrogenase (G6PD) deficiency, arises due to specific mutations. While the prevailing approach for investigating G6PD variants involves biochemical analysis, the intricate structural details remain limited, impeding a comprehensive understanding of how different G6PD variants of varying classes impact their functionality. This study examined the dynamic properties of G6PD wild types and six G6PD variants from different classes using molecular dynamic simulation (MDS). The wild-type and variant G6PD structures unveil high fluctuations within the amino acid range of 274-515, the structural NADP+ binding site, pivotal for enzyme dimerization. Specifically, two …


Ethanol Leaf Extracts Of Anogeissus Leiocarpus In Antioxidants And Hepatotoxic Effects Of Escherichia Coli Infected Swiss Mice, Fred Coolborn Akharaiyi, Chioma Bertha Ehis-Eriakha, Peter Taiwo Olagbemide, Stephen Eromosele Akemu Feb 2024

Ethanol Leaf Extracts Of Anogeissus Leiocarpus In Antioxidants And Hepatotoxic Effects Of Escherichia Coli Infected Swiss Mice, Fred Coolborn Akharaiyi, Chioma Bertha Ehis-Eriakha, Peter Taiwo Olagbemide, Stephen Eromosele Akemu

BioMedicine

Introduction: Diseases caused by bacteria can be managed with medicinal plants with rightful dosage that will not affect body physiology and organs.

Aim: This research aimed to evaluate the antioxidants and the effects of Anogeisus leiocarpus on liver function.

Materials and Methods: Ethanol leaf extracts were processed for antioxidants and hepatotoxic effects using animal models. Group one (negative control) was given access to water and regular feed, group two (positive control) was dosed with 107 CFU/ml of Escherichia coli O157:H7, and groups 3-6 were dosed with 107 E. coli O157:H7 for 3 days and treated with extract concentrations of 12, …


Impact And Prevalence Of Comorbidities And Complications On The Severity Of Covid-19 In Association With Age, Gender, Obesity, And Pre-Existing Smoking: A Meta-Analysis, Soulandi Djorwé, Amale Bousfiha, Néhémie Nzoyikorera, Joseph Nyandwi, Bellamine Kawthar, Abderrahim Malki Feb 2024

Impact And Prevalence Of Comorbidities And Complications On The Severity Of Covid-19 In Association With Age, Gender, Obesity, And Pre-Existing Smoking: A Meta-Analysis, Soulandi Djorwé, Amale Bousfiha, Néhémie Nzoyikorera, Joseph Nyandwi, Bellamine Kawthar, Abderrahim Malki

BioMedicine

Background: COVID-19 patients usually present multiple comorbidities and complications associated with severe forms of SARS-CoV-2 infection. This study aimed to assess the risk factors and prevalence of comorbidities and complications contributing to the severity of COVID-19.

Methods: This meta-analysis was performed according to PRISMA guidelines. We searched various databases, including PubMed, Google Scholar, and Scopus (between 2020 and 2023), for eligible studies for this meta-analysis.

Results: Thirty-three studies were eligible, including 85812 patients, of which 36% (30634/85812) had severe disease, whereas 64% (55178/85812) had non-severe disease. Severe cases were potentially correlated with the following factors: gender (male) (odd ratio (OR) …


Biomedicines In Longevity And Aging The Quest To Resist Biological Decline, Raymond D D Raymond Feb 2024

Biomedicines In Longevity And Aging The Quest To Resist Biological Decline, Raymond D D Raymond

BioMedicine

Aging is considered part of the natural process of life, however in recent years medical literature has started to show that specific facets of aging are beginning to be understood and those specific factors may even be considered preventable with various measures as this paper will demonstrate. Aging is also considered the number one cause of poor quality of life, disease, disability, and death, so the importance of understanding the aging process and how to control certain aspects of it cannot be underestimated when age related suffering is factored in. The causes of aging are now becoming well understood, and …


A Brief Literature Review Of Low-Level Laser Therapy For Treating Amyotrophic Lateral Sclerosis And Confirmation Of Its Effectiveness, Sergey Vladimirovich Moskvin Feb 2024

A Brief Literature Review Of Low-Level Laser Therapy For Treating Amyotrophic Lateral Sclerosis And Confirmation Of Its Effectiveness, Sergey Vladimirovich Moskvin

BioMedicine

Introduction: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with a steadily progressive course due to the death of central and peripheral motor neurons responsible for voluntary movements. Low-level laser therapy (LLLT) is a treatment method unique in its universality and efficacy, particularly for neurodegenerative diseases.

Methods: In this review, we discuss the effect and application of LLLT in the treatment of ALS. A literature search for English and Russian publications for the keywords "Amyotrophic Lateral Sclerosis", "Low-Level Laser Therapy" was performed using PubMed, Scopus, Google Scholar, Web of Science and Russian Science Citation Index (RSCI) databases.

Results: The article …


Physical Properties Of Odorants Affect Behavior Of Trained Detection Dogs During Close-Quarters Searches, Daniel Mejia, Lydia Burnett, Nicholas Hebdon, Peter Stevens, Alexis Shiber, Clay Cranston, Lauryn Degreeff, Lindsay D. Waldrop Feb 2024

Physical Properties Of Odorants Affect Behavior Of Trained Detection Dogs During Close-Quarters Searches, Daniel Mejia, Lydia Burnett, Nicholas Hebdon, Peter Stevens, Alexis Shiber, Clay Cranston, Lauryn Degreeff, Lindsay D. Waldrop

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Trained detection dogs have a unique ability to find the sources of target odors in complex fluid environments. How dogs derive information about the source of an odor from an odor plume comprised of odorants with different physical properties, such as diffusivity, is currently unknown. Two volatile chemicals associated with explosive detection, ammonia (NH3, derived from ammonium nitrate-based explosives) and 2-ethyl-1-hexanol (2E1H, associated with composition C4 plastic explosives) were used to ascertain the effects of the physical properties of odorants on the search behavior and motion of trained dogs. NH3 has a diffusivity 3.6 times that of …


2022 Census Of Agriculture: Nebraska Highlights, Kathleen Brooks, Bradley D. Lubben Feb 2024

2022 Census Of Agriculture: Nebraska Highlights, Kathleen Brooks, Bradley D. Lubben

Cornhusker Economics

In February 2024, the United States Department of Agriculture National Agricultural Statistics Service published data from the 2022 Census of Agriculture. This data is collected every five years. The current article highlights a few of the Nebraska numbers. Two significant highlights from the data are the total number of farms and the total value of production. U.S. farm numbers declined modestly in the U.S. from 2.04 million in 2017 to 1.90 million in 2022. The total value of production for U.S. farms and ranches increased substantially from $388.5 billion in 2017 to $543.1 billion in 2022. Crop production accounted for …


Quantifying Demand And Willingness To Pay For Local Food Production, Mario Ortez, Taylor Thompson, Valerie Kilders, Nicole Olynk Widmar Feb 2024

Quantifying Demand And Willingness To Pay For Local Food Production, Mario Ortez, Taylor Thompson, Valerie Kilders, Nicole Olynk Widmar

Department of Agricultural Economics Faculty Publications

The location of production and processing has had an increasingly prominent role in discussions regarding food systems today. Acknowledging the increasing importance, we study consumer preferences for and perception of local products with a particular focus on how willingness to pay (WTP) for local origin indication differs across products, types of designations, and rurality of the individual's geographic location. Using data collected through an online survey, we focused on Indiana residents’ preferences for sweet corn and Barbecue (BBQ) sauce with the sample representing both rural and urban consumers across all twelve economic growth regions in the state. Results reveal significant …