Life Sciences Commons^™

Effects Of Balance Training On Spinal Reflexive Excitability Modulation, Corticospinal Excitability, And Balance Performance In Individuals With Chronic Ankle Instability, Sunghoon Chung

Rehabilitation Sciences Theses & Dissertations

Chronic ankle instability (CAI) is a neurophysiologic deficit resulting in diverse sensorimotor impairments. Following acute ankle sprains, pain, mechanical instability, and joint deafferentation reduce sensory input to the central nervous system (CNS). In response, the CNS sends altered motor signals to lower extremity muscles. These CNS changes contribute to various neuromuscular impairments in CAI patients, the most common of which is reduced balance performance. Specifically, CAI patients struggle to modulate spinal reflex excitability of the soleus muscle when progressing from simpler to more complex balance tasks. This overreliance on spinal reflexes results in inconsistent activation of the ankle stabilizing muscle. …

The Volleyball Attack: Training, Kinematics, And The Role Of The Torso, Kiara Baeleah Barrett

Human Movement Studies & Special Education Theses & Dissertations

Volleyball is an explosive, dynamic sport popular around the globe. The volleyball attack is the predominant point-scoring avenue and the point of interest for many coaches and players. As this motion is repeated many times throughout the course of a match, it is linked to overuse injuries at the shoulder. The purpose of this dissertation is to investigate methodological approaches for research in this movement as well as establishing mechanisms for improving performance and the health of the volleyball players’ shoulder.

For the first study, a systematic review of published literature was performed to ascertain training protocols beneficial to volleyball …

Did God Create Viruses?, James Hayward

Faculty Publications

No abstract provided.

Varecia Rubra (Red Ruffed Lemur) Diel Activity And Calling At Andranobe, Masoala National Park, Madagascar, Hannah Elena Hilden-Reid

Dissertations and Theses

With respect to the natural variation in abiotic and biotic conditions present between daytime and nighttime periods, many animal species show evolutionary adaptations specialized for diurnality, nocturnality, or crepuscularity. Biologists have traditionally viewed categorizations of this kind as fixed within taxonomic groups, emphasizing how intricately species’ survival is contingent on the ability to adapt to low light, high light, or twilight conditions. However, movement away from such distinct temporal niche categories began within chronobiological studies following the discovery of more flexible patterns of activity in numerous taxa during the late 1970s. This shift generated increased interest in elucidating the complex …

A Comparative Study Of A Non-Small Cell Lung Cancer Associated Egfr Missense Variant Of Uncertain Significance, Vanessa Mejia

Theses

Non-small cell lung cancer (NSCLC) is a form of lung cancer that can be driven by heightened activity of epidermal growth factor receptor encoded by the EGFR gene. Genetic variants in EGFR have been identified that lead to abnormal cell growth and tumorigenesis. The objectives of this study was to 1) determine if an EGFR variant of uncertain significance (VUS) associated with NSCLC is potentially damaging based on evaluation of the ortholog let-23 in the model organism, C. elegans, and 2) identify conserved missense VUS loci associated with NSCLC. Through ClinVar, the EGFR VUS c.845G>C(p.Gly282Ala) was identified in …

Asthmatic Patients With High Serum Amyloid A Have Proinflammatory Hdl: Implications For Augmented Systemic And Airway Inflammation., Xianglan Yao, Maryann Kaler, Xuan Qu, Rama Satyanarayana Raju Kalidhindi, Denis Sviridov, Amaury Dasseux, Eric Barr, Karen Keeran, Kenneth R. Jeffries, Zu-Xi Yu, Meixia Gao, Scott Gordon, Amisha V. Barochia, Joni Mills, Shahid Shahid, Nargues A. Weir, Or Kalchiem-Dekel, Patricia Theard, Martin P. Playford, Mario Stylianou, Wendy Fitzgerald, Alan T. Remaley, Stewart J. Levine

Physiology Faculty Publications

RATIONALE: Serum amyloid A (SAA) is bound to high-density lipoproteins (HDL) in blood. Although SAA is increased in the blood of patients with asthma, it is not known whether this modifies asthma severity.

OBJECTIVE: We sought to define the clinical characteristics of patients with asthma who have high SAA levels and assess whether HDL from SAA-high patients with asthma is proinflammatory.

METHODS: SAA levels in serum from subjects with and without asthma were quantified by ELISA. HDLs isolated from subjects with asthma and high SAA levels were used to stimulate human monocytes and were intravenously administered to BALB/c mice.

RESULTS: …

Shigella Flexneri Diguanylate Cyclases Regulate Pathogenesis, Ruchi Ojha

Dissertations

The intracellular human pathogen Shigella invades the colonic epithelium to cause disease. Prior to colon invasion, this bacterium navigates through different environments within the human body, including acidic conditions in the stomach and the small intestine which contains antimicrobial molecules including bile acids. To adapt to changing environments, Shigella uses the bacterial second messenger c-di-GMP signaling system. C-di-GMP is synthesized by diguanylate cyclases (DGCs) encoding GGDEF domains. Shigella encodes 10 DGCs in its genome, but 6 of these genes have acquired mutations that presumably inactivated the c-di-GMP synthesis activity of these enzymes. In this study, we first expressed VCA0956, a …

Systematics, Biogeography, And Floral Trait Evolution Of The Plant Genus, Medinilla (Melastomataceae), John Peter Quakenbush

Dissertations

Medinilla is a large paleotropical genus in the plant family Melastomataceae with a long history of systematic uncertainty. The first objective of this research is to test the monophyly of Medinilla. A species tree is estimated using 599 nuclear gene trees, and 87 concatenated chloroplast genes are used to estimate the plastid phylogeny. Sampling includes 272 Medinilla and outgroups. Pachycentria and Plethiandra are resolved within Medinilla. Other fleshy-fruitedgenera long associated with Medinilla (i.e., Catanthera, Heteroblemma, Kendrickia) belong to other clades. With this new evolutionary framework, an infrageneric classification system is proposed for Medinilla consisting of …

Beneficial Effects Of Exercise On Glial Cell Line-Derived Neurotrophic Factor Content And Endplate Morphology In Skeletal Muscle Of Aging Male And Female Rats, Juliana M. Vangyseghem

Dissertations

Premenopausal women display lower incidence and severity of neurological disease compared to men of the same age, yet these populations are often treated similarly. A decline in neuromuscular function is associated with aging, which may be partially explained by a decline in neurotrophic factor expression with age. A possible way to maintain neuroprotection would be to regulate the production and release of a target-derived neurotrophic factor, such as glial cell line-derived neurotrophic factor (GDNF). GDNF has been shown to be the most potent survival factor for motor neurons and GDNF content of skeletal muscle has been shown to increase with …

Unveiling Motivations Behind First-Generation Farming, Lucas D. Kisiel

Senior Honors Projects

In the contemporary era, traditional farming practices have

faded as industrialization reshaped agricultural landscapes.

However, a noteworthy phenomenon has emerged: individuals

willingly embrace farming, even without familial legacy. This

project aims to delve into the personal incentives driving

individuals towards farming careers. Specifically, it seeks to

shed light on the challenges encountered during farm

establishment and subsequent endeavors. By focusing on first-

generation farmers, this study explores personal motivations

that influence career choices in farming without the pressures

of familial tradition. For some, it's a quest for fulfillment, a

departure from the monotony of office work to engage in

something …

04.01.2024 Orsp Connect, Liz Williamson

ORED Newsletter

NSF Conference, Jennifer Baumbaugh, Sustainable Food Packaging research, Export Control Policy Update

Nourishtank: An Innovative Program On Solving Hunger, Palak Gupta, Ashley Sullivan, Kristin Hoch, Lea Palmer, Jocelin Gibson, Mateja Savoie-Roskos, Heidi Leblanc

Outcomes and Impact Quarterly

NourishTank, a Shark Tank-style event, saw students propose food and nutrition insecurity solutions. Twenty-eight students formed 11 teams, promoting interdisciplinary collaboration. The winning idea, 'Farm2Fork Gone Mobile,' earned $1,000 toward their proposed project. NourishTank, through partnerships and media, highlights student-driven efforts combating food insecurity and raising awareness.

Balancing Agriculture And Wildlife: The Impact Of Elk And Deer Grazing On Farming And Ranching Lands, Ethan Gilliam, Anna Gilliam, Jody Gale

Outcomes and Impact Quarterly

This article examines producers' perceptions of elk and deer grazing on their lands through a survey conducted at the American Farm Bureau Federation (AFBF) National Conference. With 140 complete responses, the study underscores the varying impacts of elk/deer grazing. The findings emphasize the need for enhanced collaboration between agricultural stakeholders and wildlife management authorities to address wildlife grazing impacts effectively. These findings also address the critical opinion of producers toward wildlife inside and outside of their private operations, as well as the interactions between producers and wildlife authorities.

A Novel Interaction Of Nesidiocoris Tenuis (Hemiptera: Miridae) As A Biological Control Agent Of Bactericera Cockerelli (Hemiptera: Triozidae) In Potato, Gabriela Esparza-Diaz, Raul Villanueva, Ismael E. Badillo-Vargas

Entomology Faculty Publications

Nesidiocoris tenuis (Hemiptera: Miridae) is a generalist predator commonly used to control the whitefly Bemisia tabaci in Europe. This mirid has been found and established in South Texas, where it was initially observed feeding on nymphs of the psyllid Bactericera cockerelli (Hemiptera: Triozidae) in open tomato fields. B. cockerelli is the vector of the fastidious bacterium “Candidatus Liberibacter solanacearum” that causes diseases in several solanaceous crops, including zebra chip (ZC) disease in potatoes. There is a need to better understand how this predator impacts the control of important crop pests, such as potato psyllids. We assessed the interactions between N. …

New Voices For A Better Society, Stephanie J. Diem, Baindu L. Bayon, Hussam Mahmoud, Mary L. Garcia- Cazarin, Michael J. Martin, Clare C. Rittschof, Patricia Silveyra, Umut A. Gurkan, Alison Boland- Reeves, Dalal Najib, Flannery Wasson

Entomology Faculty Publications

No abstract provided.

Toward Transparent Taxonomy: An Interactive Web-Tool For Evaluating Competing Taxonomic Arrangements, Oksana V. Vernygora, Felix A. H. Sperling, Julian R. Dupuis

Entomology Faculty Publications

Informative and consistent taxonomy above the species level is essential to communication about evolution, biodiversity and conservation, and yet the practice of taxonomy is considered opaque and subjective by non-taxonomist scientists and the public alike. While various proposals have tried to make the basis for the ranking and inclusiveness of taxa more transparent and objective, widespread adoption of these ideas has lagged. Here, we present TaxonomR, an interactive online decision-support tool to evaluate alternative taxonomic classifications. This tool implements an approach that quantifies the criteria commonly used in taxonomic treatments and allows the user to interactively manipulate weightings for different …

The Influence Of Cards Toxin In Abetting The Virulence Of Mycoplasma Pneumoniae, Layla Abdulbaki

Posters - 2024

Mycoplasma pneumonia is a human bacterial pathogen known to induce chronic upper and lower respiratory infections. This bacterium commonly causes acute, chronic infections, such as atypical pneumonia, and spreads through droplet transmission (> 5 microns). M. pneumoniae damages cells by attacking the epithelium of the respiratory tract, resulting in epithelium shedding. Infection of the airway tract by M. pneumoniae will usually express itself in people with chronic symptoms such as coughing, dyspnea, diarrhea, and epiphora. With this being said, this bacterium is ambit, meaning that it is versatile in who it affects (children to adults), how it manifests (pneumonia, tracheobronchitis, …

Expression And Purification Of Domain 1 Of The Cards Toxin, Dylan Andrews, Allison Woods, Ahmad Galaleldeen

Posters - 2024

Mycoplasma pneumoniae (Mp) is an atypical bacterium that is linked to various respiratory diseases such as walking pneumonia and asthma. Upon infection, Mp produces a 591-aa virulence factor known as Community Acquired Respiratory Distress Syndrome Toxin (CARDS TX). The crystal structure of this 591-aa cytotoxin reveals a triangular molecule comprised of an N-terminal ADP-ribosylating domain and a Cterminal tandem β-trefoil domain that is responsible for vacuolation of the host’s cells. Based on structural and sequence homology to other ADP ribosylating toxins, the NAD+ binding site has been predicted, yet none of the published structures of the CARDS toxin contain NAD+. …

Does The Number Of Individuals Present In The Water Affect Dolphin Activity Levels, Erika Aguirre, Xavier Castillo, Quinn Gallagher

Posters - 2024

Bottlenose dolphin behavior and complex social structures have interested humans over the years. Dolphin deviation in these behaviors has been measured many ways such as activity levels, space used, and time of day. A study was focused on dolphin interactions with humans, patterns of lagoon space utilization, and temporal factors. Data have been collected at the Roatán Institute for Marine Sciences (RIMS), which houses a diverse sample of 16-18 dolphins. No correlation was observed between increased human presence and levels of dolphin activity. Dolphins did display higher preferences for specific lagoon areas. This variability in lagoon space utilization suggests an …

Mycoplasma Pneumoniae: Long-Term Effects On The Lungs, Alyssa David

Posters - 2024

Mycoplasma pneumoniae is a bacterium responsible for causing pneumonia in the lungs. M. pneumoniae is responsible for an average of 2 million cases of bacterial pneumonia in the United States each year (ASM Journal). When M. pneumonia infects the lungs, it releases community-acquired respiratory distress syndrome (CARDS toxin), which is capable of two enzymatic functions, vacuolization and ADP-ribosylation. ADPribosylation is found in the N-terminal domain of the protein, and the glutamic acid at amino acid residue 132 is critical for enzymatic function. There is evidence that the vacuolization function is encoded by the C-terminal of the protein. Preliminary findings in …

Assessing Bottlenose Dolphin (Tursiops Truncatus) Behavioral Responses To Discriminative Stimulus During Dolphin Interaction Programs (Dips), Megan Davis, Hannelore Tampipi

Posters - 2024

Dolphin-human interaction programs (DIP) References have become a popular experience offering humans an opportunity to interact or swim with cetaceans, most often bottlenose dolphins (Tursiops truncatus).

● Previous studies on dolphin-human interactions have been centered on therapeutic results for humans (Brensing et al., 2005), guests’ future conservation efforts, and educational efficacy (Miller et al., 2013) rather than welfare or outcomes for dolphins (Smith, 1981).

● Under human care, trainers request behaviors from dolphins typically via a hand signal as a discriminative stimulus (SD).

● Resulting behavioral responses to these SDs during interaction programs may suggest willingness to participate (WTP), and …

Rewilding The ”Wild West”: Restoring Bison Populations In The American Prairie, Ana Christina Diaz

Posters - 2024

Historically, North America was home to a biodiverse and environmentally rich land, from beavers, mountain lions, numerous bird and insect species, and North America’s largest land mammal, the bison (Figure 1). The American bison (Bison bison), also referred to as buffalo, are a keystone species in their environments, meaning their absence can have detrimental effects on other species. Bison are environmental engineers that create a “mosaic of habitats” with their behaviors including wallowing, grazing, and defecating (American Prairie Foundation 2024). Bison once roamed from Canada to Mexico with a population estimated around 50 million but were tragically almost wiped to …

Comparing Activity Levels Of Bottlenose Dolphins (Tursiops Truncatus) During Snorkels To A Swimming Researcher, Sabrina Drouin, Erika Aguirre, Charles Lares

Posters - 2024

Bottlenose dolphins under professional care are provided with a range of enrichments that have a variety of features and levels of complexity at various frequencies (Lauderdale et al., 2022). In a previous study conducted by Brensing et al. (2015), they found that dolphins seemed to be attracted to adult swimmers, but only if they had ample space to swim. The purpose of this study is to examine dolphin activity level under two different conditions with humans in the water. We hypothesize that dolphin activity level will be higher during snorkel sessions than a single swimming researcher because there are more …

Total Syntheses Of Hosieines A-C, Jiayang Zhang, Xu Yan, Qing-Bao Zhang, Fang Wang, Bin Yang, Yang Yang

Children’s Nutrition Research Center Staff Publications

The collective total syntheses of (±)-hosieines A-C with a cage-like tetracyclic framework have been realized, which includes the first syntheses of hosieines B-C. The key strategy of the synthesis employs a one-pot domino reaction that involves Cu-catalyzed [3+2] cycloaddition, 1,6-enone formation, and 1,6-aza-Michael addition forming the 5/6/6-aza-tricyclic skeleton. Other salient synthetic tactics comprise a challenging double bond migration and a 1,4-aza-Michael addition reaction to afford the tetracyclic framework.

An Investigation On The Intricacies Of Epigenetic Modulations In The Pathogenesis Of Human Papillomavirus-Associated Cervical Cancer: A Comprehensive Meta-Narrative Synthesis, Jade Carolina Cabello, Marcella Victoria Ras, Katelyn Thy Nhung Tran, Athit Voytas

Research Methods Poster Session 2024

Abstract

Objective: To conduct a meta-analysis of the available and relevant literature on E1/E2 genes and their affect on the epigenetics of Human Papillomavirus caused uterine cervical cancer.

Background/Significance: Human Papillomavirus is strongly linked to cervical cancer, and cervical cancer is the fourth most common type of cancer in women. 99.7% of patients with cervical cancer have a “high risk HPV genotype” which factors greatly into the causation if their diagnosis. The HPV vaccine that came out in 2006 has greatly decreased cervical cancer in the population as well as increased the preventative chances of highly susceptible individuals.

Methods: To …

Some Notable Women Botanists In The Vas: Their Roles In Supporting The Development Of The Modern Flora Of Virginia, Marion B. Lobstein

Virginia Journal of Science

With the publishing of the 2012 Flora of Virginia by the Foundation of the Flora of Virginia Project, the dream of modern flora for Virginia was realized. This was a goal of the Virginia Flora Committee of the Virginia Academy of Science as well as other groups such as the Virginia Botanical Associates and the Virginia Native Plant Society. The Flora of Virginia and the 2017 Flora of Virginia App were realized with the work, support, and encouragement of many individuals and organizations. This paper focuses on the lives, contributions, and work of six women botanists in the Academy who …

Ecological Studies Of Wolves On Isle Royale, Sarah Hoy, Rolf O. Peterson, John Vucetich

Ecological Studies of Wolves on Isle Royale

Annual Report 2023-2024

Occupational Engagement In Recreational Sports For The Deaf And Hard Of Hearing: An Employee Guidebook, Colleen Mcerlean, Mary Ann Smith, Christopher Ebner

Spring 2024 Virtual OTD Capstone Symposium

An employee guidebook to help increase occupational engagement within recreational sports for the Deaf and Hard of Hearing population in the Austin, TX area.

The Effects Of Land Use Change On Ant Communities In New England, Amelia K.L. Curry, Joseph A. Nelsen, Dale R. Stevens, Kaitlyn A. Mathis

Biology

Urbanisation and agricultural expansion are two of the most prevalent and intense forms of land use change worldwide and can have dramatic consequences on biodiversity and biotic community structure. Ants are extremely widespread, ecologically diverse and small ectotherms that are sensitive to changes from a wide range of environmental factors. Therefore, ants make an ideal study organism to examine the effects of anthropogenic land use change on biotic communities. In this study, we examined differences in ant species richness and community composition between urban parks, farms and forest fragments, and related these differences to environmental factors that vary among each …

3rd Place Research Paper: Cultural Attitudes Towards Ethnic Cuisine In Italy, Rachel Berns

Kevin and Tam Ross Undergraduate Research Prize

Italy has become a common “landing country” for many European and Asian immigrants, creating a perception of invasion that has led to cultural reactionism masked in the reinforcement of “traditional cuisine.” For so-called traditional foods to endure, they must continually be reinvented, bearing different meanings and social values throughout time and space while accumulating rich, cultural baggage that serves as a powerful marker of identity in a given society. This paper explores the role of traditional cuisine in Italian national identity and pride, and the subsequent historical culinary antagonism maintained in widespread attitudes toward ethnic cuisine in Italy. Through an …