Life Sciences Commons^™

The Santa Clara, 2024-05-28, Santa Clara University

The Santa Clara

No abstract provided.

Farmer's Adaptive Capacity And Adoption Of Strategies To Climate Change Among Mountain Communities In Nepal, Tanvir Hossain

LSU Master's Theses

Climate change presents significant challenges to agriculture worldwide, particularly where farming is central to livelihoods. This phenomenon has been linked to decreasing crop yields due to rising temperatures and reduced rainfall, particularly affecting low-income countries with limited adaptive capabilities. Grasping how farmers perceive climate change is essential for developing effective adaptation strategies to lessen its adverse impacts. This study concentrated on investigating the perceptions and adaptive strategies employed by smallholder farmers in Nepal's Mustang district, utilizing primary data sources. Data from 131 randomly selected households were gathered through structured interviews, while focus group discussions provided qualitative insights into farmers' views …

Methods To Manage Survey Error Within Economic Contribution Analysis, Madison Jane Plaisance

LSU Master's Theses

The primary objective of this research was to employ strategical methodological approaches to assess the economic value of specific sub-sectors of the green industry within Louisiana. I specifically focused on addressing errors associated with utilizing survey data as the primary data source in such analyses and utilizing approaches such as post-survey stratification and bootstrapping techniques to mitigate these errors.

To achieve this aim, a group of green industry professionals and I selected sectors for analysis based on horticultural licenses issued by the Louisiana Department of Agriculture and Forestry (LDAF). Through collaboration with advisors from the Louisiana Nursery and Landscape Association …

Hairry Potter World: Are Gel And Oil The Sorcerers Magic To Altering External Cocaine And Be Concentrations In Hair, Esther Abady

Student Theses

Hair external contamination poses significant challenges to the interpretation of hair testing results. Previous studies have shown that cosmetic hair treatments can reduce the concentration of drugs already present in the hair shaft. However, the impact of these treatments on externally deposited drugs remains largely unexplored. This study aimed to investigate how gel and oil treatments affect external contamination by cocaine and benzoylecgonine. Fifteen authentic hair samples, with various colors and textures, were collected from volunteers and confirmed negative for cocaine and benzoylecgonine using a fully validated LC-MS/MS method. Each sample was divided into three groups: Group A underwent a …

Nature Of The Evidence Base And Approaches To Guide Nutrition Interventions For Individuals: A Position Paper From The Academy Of Nutrition Sciences, Kevin Whelan

Faculty, Staff and Student Publications

This Position Paper from the Academy of Nutrition Sciences is the third in a series which describe the nature of the scientific evidence and frameworks that underpin nutrition recommendations for health. This paper focuses on evidence which guides the application of dietary recommendations for individuals. In some situations, modified nutrient intake becomes essential to prevent deficiency, optimise development and health, or manage symptoms and disease progression. Disease and its treatment can also affect taste, appetite and ability to access and prepare foods, with associated financial impacts. Therefore, the practice of nutrition and dietetics must integrate and apply the sciences of …

The Biology Of The Facultative Halophyte Atriplex Patula L., Richard Stalter, Robert I. Lonard

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

Atriplex patula L. is a facultative halophyte that tolerates low to moderate levels of salinity and occurs on the margins of coastal salt marshes, roadsides, in agricultural fields, and in other areas where disturbance has occurred. The genus Atriplex L. is represented by about 250 species globally and has recently been included in the family Amaranthaceae subfamily Chenopodioidae. Atriplex patula was possibly introduced in North America from Europe, Asia or North Africa in the 18th century. Because the stems and leaves accumulate and store heavy metal pollutants, A. patula has been suggested for use in habitat remediation.

The Janus Kinase 1 Is Critical For Pancreatic Cancer Initiation And Progression, Hridaya Shrestha, Patrick Rädler, Rayane Dennaoui, Madison Wicker, Nirakar Rajbhandari, Yunguang Sun, Amy Peck, Kerry Vistisen, Aleata Triplett, Rafic Beydoun, Esta Sterneck, Dieter Saur, Hallgeir Rui, Kay-Uwe Wagner

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

Interleukin-6 (IL-6)-class inflammatory cytokines signal through the Janus tyrosine kinase (JAK)/signal transducer and activator of transcription (STAT) pathway and promote the development of pancreatic ductal adenocarcinoma (PDAC); however, the functions of specific intracellular signaling mediators in this process are less well defined. Using a ligand-controlled and pancreas-specific knockout in adult mice, we demonstrate in this study that JAK1 deficiency prevents the formation of KRAS^G12D-induced pancreatic tumors, and we establish that JAK1 is essential for the constitutive activation of STAT3, whose activation is a prominent characteristic of PDAC. We identify CCAAT/enhancer binding protein δ (C/EBPδ) as a biologically relevant …

Loss Of Lpar6 And Cab39l Dysregulates The Basal-To-Luminal Urothelial Differentiation Program, Contributing To Bladder Carcinogenesis, Sangkyou Lee, Jolanta Bondaruk, Yishan Wang, Huiqin Chen, June Goo Lee, Rachel D Mullen, Jiansong Chen, Ziqiao Wang, Hui Yao, Pawel Kus, Joon Jeong, Ilkyun Lee, Woonyoung Choi, Neema Navai, Charles Guo, Colin Dinney, Keith Baggerly, Cathy Mendelsohn, David Mcconkey, Richard R Behringer, Marek Kimmel, Peng Wei, Bogdan Czerniak

Faculty, Staff and Student Publications

We describe a strategy that combines histologic and molecular mapping that permits interrogation of the chronology of changes associated with cancer development on a whole-organ scale. Using this approach, we present the sequence of alterations around RB1 in the development of bladder cancer. We show that RB1 is not involved in initial expansion of the preneoplastic clone. Instead, we found a set of contiguous genes that we term "forerunner" genes whose silencing is associated with the development of plaque-like field effects initiating carcinogenesis. Specifically, we identified five candidate forerunner genes (ITM2B, LPAR6, MLNR, CAB39L, and ARL11) mapping near RB1. Two …

Astrocytic Slc4a4 Regulates Blood-Brain Barrier Integrity In Healthy And Stroke Brains Via A Ccl2-Ccr2 Pathway And No Dysregulation, Qi Ye, Juyeon Jo, Chih-Yen Wang, Heavin Oh, Jiangshan Zhan, Kyoung In Kim, Yana K Reshetnyak, Sung Yun Jung, Zheng Chen, Sean P Marrelli, Hyun Kyoung Lee

Faculty, Staff and Student Publications

Astrocytes play vital roles in blood-brain barrier (BBB) maintenance, yet how they support BBB integrity under normal or pathological conditions remains poorly defined. Recent evidence suggests that ion homeostasis is a cellular mechanism important for BBB integrity. In the current study, we investigated the function of an astrocyte-specific pH regulator, Slc4a4, in BBB maintenance and repair. We show that astrocytic Slc4a4 is required for normal astrocyte morphological complexity and BBB function. Multi-omics analyses identified increased astrocytic secretion of CCL2 coupled with dysregulated arginine-NO metabolism after Slc4a4 deletion. Using a model of ischemic stroke, we found that loss of Slc4a4 exacerbates …

Differentiation Syndrome Associated With Treatment With Idh2 Inhibitor Enasidenib: Pooled Analysis From Clinical Trials, Pau Montesinos, Amir T Fathi, Stéphane De Botton, Eytan M Stein, Amer M Zeidan, Thomas Prebet, Iryna Bluemmert, Xin Yu, Courtney D Dinardo

Faculty, Staff and Student Publications

Treatment with enasidenib, a selective mutant isocitrate dehydrogenase isoform 2 (IDH2) inhibitor, has been associated with the development of differentiation syndrome (DS) in patients with acute myeloid leukemia (AML). Studies on the incidence and clinical features of DS are limited in this setting, and diagnosis is challenging because of nonspecific symptoms. This study assessed the incidence, diagnostic criteria, risk factors, and correlation with clinical response of DS based on the pooled analysis of 4 clinical trials in patients with IDH2-mutated AML treated with enasidenib as monotherapy, or in combination with azacitidine or with chemotherapy. Across the total AML population, 67 …

Smoking Cessation After Initial Treatment Failure With Varenicline Or Nicotine Replacement: A Randomized Clinical Trial, Paul M Cinciripini, Charles E Green, Sanjay Shete, Jennifer A Minnix, Jason D Robinson, Seokhun Kim, Diane Beneventi, Janice A Blalock, Francesco Versace, Maher Karam-Hage

Faculty, Staff and Student Publications

Importance: Most people who smoke do not quit on their initial attempt.

Objective: To determine the best subsequent strategy for nonabstinence following initial treatment with varenicline or combined nicotine replacement therapy (CNRT).

Design, setting, and participants: Using a double-blind, placebo-controlled, sequential multiple assignment randomized trial, 490 volunteers were randomized to receive 6 weeks of varenicline or CNRT. After 6 weeks, nonabstainers were rerandomized to continue, switch, or increase medication dosage for 6 additional weeks. The study was conducted from June 2015 through October 2019 in a Texas tobacco treatment clinic.

Interventions: The initial treatment was 2 mg/d of varenicline or …

A Multicenter Study Of Venetoclax-Based Treatment For Patients With Richter Transformation Of Chronic Lymphocytic Leukemia, Paul J Hampel, Mahesh Swaminathan, Kerry A Rogers, Erin M Parry, Jan A Burger, Wei Ding, Jonathan M Hyak, Nitin Jain, Saad S Kenderian, Yucai Wang, William G Wierda, Jennifer A Woyach, Sameer A Parikh, Philip A Thompson

Faculty, Staff and Student Publications

Patients with chronic lymphocytic leukemia (CLL) who develop Richter transformation (RT) have a poor prognosis when treated with chemoimmunotherapy regimens used for de novo diffuse large B-cell lymphoma. Venetoclax, a BCL2 inhibitor, has single-agent efficacy in patients with RT and is potentially synergistic with chemoimmunotherapy. In this multicenter, retrospective study, we evaluated 62 patients with RT who received venetoclax-based treatment outside of a clinical trial, in combination with a Bruton tyrosine kinase inhibitor (BTKi; n=28), rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone (R-CHOP) (n=13), or intensive chemoimmunotherapy other than R-CHOP (n=21). The best overall and complete response rates were 36%/25%, 54%/46%, and …

Advancing Objective Mobile Device Use Measurement Inchildren Ages 6–11 Through Built-In Device Sensors: A Proof-Of-Concept Study, Olivia L. Finnegan, Robert Glenn Weaver Med, Phd, Hongpeng Yang, James W. White, Srihari Nelakuditi, Zifei Zhong, Rahul Ghosal Ph.D., Yan Tong, Aliye B. Cepni, Elizabeth L. Adams, Sarah Burkart Mph, Ph.D., Michael W. Beets Med, Mph, Phd, Bridget Armstrong Ph.D.

Faculty Publications

Mobile devices (e.g., tablets and smartphones) have been rapidly integrated into the lives of children and have impacted howchildren engage with digital media. The portability of these devices allows for sporadic, on-demand interaction, reducing theaccuracy of self-report estimates of mobile device use. Passive sensing applications objectively monitor time spent on a givendevice but are unable to identify who is using the device, a significant limitation in child screen time research. Behavioralbiometric authentication, using embedded mobile device sensors to continuously authenticate users, could be applied toaddress this limitation. This study examined the preliminary accuracy of machine learning models trained on iPad …

Novel In Situ Synthesis Of Copper Oxide Nanoparticles In Epoxy Network: Kinetics, Composite Mechanical And Dielectric Properties, Elena Bobina, Maxim Danilaev, Safaa.M.R.H. Hussein, Sergey Karandashov, Vladimir Kuklin, Ivan Lounev, Konstantin Faizullin

Karbala International Journal of Modern Science

>Mechanical properties of polymer composites with dispersed nanoparticles (CDNP) depend on interaction between the nanoparticles and the polymer matrix. Strength of polymer composites significantly decreases when there is no interaction between dispersed nanoparticles and the polymer. This limits the application of functional polymer composites with dispersed nanoparticles. In this study, CDNP based on ED-20 epoxy resin with dispersed copper oxide nanoparticles was obtained.These nanoparticles were synthesized in epoxy resin before curing: the nanoparticles were obtained by decomposition of copper hydroxide by heating its solution in ED-20 resin.The kinetics of copper oxide nanoparticles formation in CDNP samples were studied using two …

Elm And Lightgbm: A Hybrid Machine Learning Technique With Intelligent Iot To Predict The Cardiovascular Disease, Gorapalli Srinivasa Rao, G Muneeswari

Karbala International Journal of Modern Science

Cardiologists can more accurately classify a patient's condition by performing an accurate diagnostic and prognosis of cardiovascular disease (CVD). The clinical diagnosis, and therapies processes within the medical field have been substantially accelerated by ML-based approaches enabled by IoT-based systems. This structure is based on IoT-based system with enabled ML approach. This study investigates an approach known as ensemble categorization, which enhances the precision of weak algorithms by integrating multiple classifiers. For effective CVD classification, we utilized Ensemble learning machine (ELM) and Light GBM. The appropriate traits are chosen to speed up the categorization process using the Gorilla Troops Optimizer …

Comparing Researchers’ Degree Of Dichotomous Thinking Using Frequentist Versus Bayesian Null Hypothesis Testing, Jasmine Muradchanian, Rink Hoekstra, Henk Kiers, Dustin Fife, Don Van Ravenzwaaij

College of Science & Mathematics Departmental Research

A large amount of scientific literature in social and behavioural sciences bases their conclusions on one or more hypothesis tests. As such, it is important to obtain more knowledge about how researchers in social and behavioural sciences interpret quantities that result from hypothesis test metrics, such as p-values and Bayes factors. In the present study, we explored the relationship between obtained statistical evidence and the degree of belief or confidence that there is a positive effect in the population of interest. In particular, we were interested in the existence of a so-called cliff effect: A qualitative drop in the …

T-Cell Redirecting Bispecific Antibodies: A Review Of A Novel Class Of Immuno-Oncology For Advanced Prostate Cancer, Julia Palecki, Amman Bhasin, Andrew Bernstein, Patrick Mille, William Tester, William Kelly, Kevin Zarrabi

Kimmel Cancer Center Faculty Papers

Novel T-cell immunotherapies such as bispecific T-cell engagers (BiTEs) are emerging as promising therapeutic strategies for prostate cancer. BiTEs are engineered bispecific antibodies containing two distinct binding domains that allow for concurrent binding to tumor-associated antigens (TAAs) as well as immune effector cells, thus promoting an immune response against cancer cells. Prostate cancer is rich in tumor associated antigens such as, but not limited to, PSMA, PSCA, hK2, and STEAP1 and there is strong biologic rationale for employment of T-cell redirecting BiTEs within the prostate cancer disease space. Early generation BiTE constructs employed in clinical study have demonstrated meaningful antitumor …

Biotechnology For Sustainable Materials: Innovating Today For A Greener Tomorrow, Shashi Kant Bhatia, Saurabh Bhatia, Maria Eugenia Inda-Webb, Konstantina Kourmentza, Tae Seok Moon, Vijai Singh, Vishal Ahuja, Jingbo Li, Sanjeet Mehariya, Jikai Zhao

School of Earth, Environmental, & Marine Sciences Faculty Publications

No abstract provided.

Du Undergraduate Showcase Abstracts: Research, Scholarship, And Creative Works, August Alexander, Kevin Summers, E. Paige Lloyd, Alyssa Aragon, Lauren Wols, Erica Larson, Colton Arciniaga, Lily Baeza, Ellie Barnett-Cashman, Sidney Barbier, Maverick Bartholomew, Ryan Bell, Trevor Briggs, Amanda Brown, Cory Marchi, Maddy Pontius, Jennifer Gallagher, Claire Kwok, Channing Bullock, Alex Mccollister, Kim Gorgens, Daniela Chavez, Yamilet Espinoza Nuñez, Giovanni Valladares Giron, William Christensen, Olivia Kachulis, Daniel Cierasynski, Brandon Cohen, Spenser Dobbs, Lindsay Goolsby, Noah Craver, Nyah Cubbison, Liam Doherty, Nicole Doris, Yan Qin, Alexander Nguyen, Lily Harmon, Shubh Todi, Naichen Zhao, Noah Fagello, Stacia Fritz, Paola Gascot-Chinea, Alex Volkova, Janelyn Geronimo, Elsie Harrington, Shane Simmons, Clarice Hise, Laura Moreno Palmer, Henry Xu, Yesu Leela Pasupula, Emily Fisher, Zachary Hogan, Colin Kleckner, Alyssa Knaus, Erin Kubat, Sam Werkema, Katie Lamberton, Lilliya Larson, Allie Leary, Vanessa Leon-Gamez, James H. Gallagher, E. Dale Broder, Robin M. Tinghitella, Emma Loeber, Alina Mali, Ixchel Marquez, Lauren Mcgrath, Ella Matthews, Grace Naegelen, Audrey Ng, Megan Lucyshyn, Rachel Brough, Alexandra Norman, Joe Ontiveros Rodriguez, Ben Dossett, Ori Miller, Janamejay Sharma, Christopher Reardon, Vincent Pandey, Regan Parish, Ren Pratt, Alisha Pravasi, Sanchari Das, Cari Reichel, Emma Robson, Victoria Rockwell, Jayce Rumsey, Steven Said, Norah Schroder, Alaina Smith, Shannon Murphy, Shujan A. Sharafeldeen, Stanley M. Kanai, James T. Nichols, David E. Clouthier, Macalia R. Augustus, Daniel Silva Rios, Scott Simpson, Anna Sparling, Chase Spurbeck, Kimberly Chiew, Christine Stadnik-Poteroba, Jacqueline Stephenson, Evelyn Stovin, Mia Supan, Lauren Tapper, Will Thrush, Anna Vogt, Michaela Walheim, Jon Weber, Hunter Whitehouse, Kansas Wood, Hayley Sayre, Lydia Mccann, Maread Mclaughlin, Kelly Krumrie, Olivia Wuttke

DU Undergraduate Research Journal Archive

Abstracts from the DU Undergraduate Research Showcase.

Caprin1 And Fmr1 Genetically Interact To Regulate The Development Of The Larval Drosophila Neuromuscular Junction, Seraphina Loukas, Scott Barbee

DU Undergraduate Research Journal Archive

Fragile X Syndrome (FXS) is the most prevalent inherited neurodevelopmental disorder and the most common single-gene cause of autism (Richter and Zhao 2021). FXS occurs due to the loss of the Fmr1 gene, and its respective protein, the Fragile X Messenger Ribonucleoprotein (FMRP). FMRP is an RNA-binding protein (RBP) with notable functions in synaptic development.  Given that cellular processes often entail the collaborative actions of multiple proteins acting as binding partners to regulate mRNA metabolism, identifying FMRP's associates is essential for comprehending FXS mechanisms. Caprin1 was identified as a high-confidence interactor via its co-immunoprecipitation with FMRP in an IP/LC experiment …

Dynamic Hydrogel-Metal-Organic Framework System Promotes Bone Regeneration In Periodontitis Through Controlled Drug Delivery, Weicheng Chiu, Anqi Li, Yulin Dai, Weichang Li, Xinchun Zhang

Faculty, Staff and Student Publications

Periodontitis is a prevalent chronic inflammatory disease, which leads to gradual degradation of alveolar bone. The challenges persist in achieving effective alveolar bone repair due to the unique bacterial microenvironment's impact on immune responses. This study explores a novel approach utilizing Metal-Organic Frameworks (MOFs) (comprising magnesium and gallic acid) for promoting bone regeneration in periodontitis, which focuses on the physiological roles of magnesium ions in bone repair and gallic acid's antioxidant and immunomodulatory properties. However, the dynamic oral environment and irregular periodontal pockets pose challenges for sustained drug delivery. A smart responsive hydrogel system, integrating Carboxymethyl Chitosan (CMCS), Dextran (DEX) …

The Effect Of Total Factor Productivity On The Food Security And Livelihood Vulnerability Of Farm Households In Bangladesh, Paresh Kumar Sarma, Mohammad Jahanghir Alam, Ismat Ara Begum, Adam M. Mckenzie

Agricultural Economics and Agribusiness Faculty Publications and Presentations

Food security and livelihood vulnerability are important issues for the economic sustainability of developing countries like Bangladesh. This study examines the influence of total factor productivity (TFP) on the livelihood vulnerability and food security of rice farming households in Bangladesh. Data from 1,841 rice farming households were extracted from the Bangladesh Integrated Household Survey (2015 and 2018) conducted by the International Food Policy Research Institute. Various statistical methods, such as the stochastic frontier model, principal component analysis, path analysis using structural equation modeling, and multivariate regression, were employed to analyze the data. The study utilizes a multivariate modeling approach that …

Estimating Increased Transient Water Storage With Increases In Beaver Dam Activity, Konrad Hafen, Joseph M. Wheaton, Brett B. Roper, Philip Bailey, William W. Macfarlane, Bethany T. Neilson, Christopher J. Tennant

Watershed Sciences Faculty Publications

Dam building by beaver (Castor spp.) slows water movement through montane valleys, increasing transient water storage and the diversity of residence times. In some cases, water storage created by beaver dam construction is correlated to changes in streamflow magnitude and timing. However, the total amount of additional surface and groundwater storage that beaver dams may create (and, thus, their maximum potential impact on streamflow) has not been contextualized in the water balance of larger river basins. We estimate the potential transient water storage increases that could be created at 5, 25, 50, and 100% of maximum modeled beaver dam capacity …

An Evaluation Of Sonderegger Pine Morphology, Kelsey Denise Shoemaker

Master's Theses

Sonderegger pine (Pinus x sondereggeri H.H. Chapm.), the naturally occurring hybrid of longleaf (Pinus palustris Mill.) and loblolly pine (Pinus taeda L.), is considered a producer of poor-quality wood due to observations of stem forking and a high number of large-diameter branches at maturity. Because landowners generally decline planting Sonderegger pine seedlings, nursery workers cull putative hybrids from longleaf pine seedling stock during lifting and processing. However, over the past 100 years, very few studies have quantified stem quality of Sonderegger pine. To gain a better understanding of the early growth and development of Sonderegger pine, evaluations of height, diameter …

Reports Of Autosomal Recessive Disease And Consanguineous Mating Within The Human Population, Johnathon L. Schluter

Master's Theses

It is anecdotally evident when investigating published reports of autosomal recessive disease that a substantial number of cases are the result of related (consanguineous) mating. This research seeks to quantify the percent of manuscripts describing autosomal recessive diseases published between 2000 and 2020 in which consanguineous mating is indicated. We analyzed 602 peer-reviewed manuscripts to identify the percentage of cases presented in which consanguineous mating was indicated, the underlying genes (novel gene or new mutation) and geographical region. These papers were accessed through a specific set of parameters on the free access PubMed Central (PMC) database. A total of 552 …

Effect Of Sex On The Accumulation Of Hepatic Mercury In Mallards Wintering In Louisiana, Latorya E. Mason

Master's Theses

The increase in mercury production through anthropogenic activities has led to a global crisis of mercury pollution that poses a significant threat to the health of both humans and wildlife. Aquatic ecosystems are especially at risk due to the creation of methylmercury, a toxic form of mercury, by sulfate-reducing bacteria in anoxic sediments and soils. Methylmercury enters the food chain where it bioaccumulates in individual organisms and then biomagnified with increasing trophic level. Aquatic birds are useful bioindicators of many pollutants, including mercury, due to their abundance and position in the food chain. Previous studies have primarily focused on mercury …

Chronic High-Salt Diet Activates Tumor-Initiating Stem Cells Leading To Breast Cancer Proliferation, Lisa Tucker, Umer Ali, Deborah A. Lannigan, Jeffrey C. Rathmell, Venkataswarup Tiriveedhi

Biology Faculty Research

Several chronic inflammatory diseases have been linked to high-salt (HS) diets. Chronic inflammation is an established causative hallmark of cancer. However, a direct role of HS diets in tumorigenesis is yet to be defined. Previous orthotopic murine breast tumor studies have shown that short-term HS diets caused inhibition of tumor growth through the activation of cytotoxic adaptive immune responses. However, there have been experimental challenges in developing a viable chronic HS-diet-based murine tumor model. To address this, we have developed a novel chronic HS diet tumor model through the sequential passaging of tumor cells in mice under HS dietary conditions. …

Post-Stocking Predation And Dispersal Of Stocked Juvenile Chinook Salmon (Oncorhynchus Tshawytscha) In Lake Oahe, South Dakota, Dylan Alan Jon Gravenhof

Biology Theses, Dissertations, and Student Creative Activity

Acoustic telemetry is a tool commonly used to better understand the fates of fish following a stocking event. Until recently, predation on stocked fish could only be inferred by observing and identifying abrupt changes in tag detection histories. Recently, a novel predation transmitter has provided better insight into how predation affects post-stocking survival. The main objectives of this study were to use these transmitters to 1) estimate predation rates on stocked juvenile Chinook Salmon in a landlocked system (Lake Oahe, South Dakota) and 2) estimate dispersal rates and residency times of the Chinook Salmon after stocking. Additionally, our secondary objectives …

Assessing The Influences Of Stocking And Introduced Alewife On Walleye Recruitment In Lake Mcconaughy, Nebraska, Logan Zebro

Biology Theses, Dissertations, and Student Creative Activity

Lake McConaughy is an important socioeconomic reservoir in Nebraska and Walleye is the priority management species. Walleye have been stocked annually since 1989 to support the Walleye population, however, adult Walleye relative abundance has steadily declined since the early 1990s. Additionally, in 1986, Alewives were introduced to improve the growth and body condition of adult Walleye, which subsequently increased the population size structure. However, Alewives can have negative influences on the recruitment of other fish species through predation and competition. Although Alewives have been in this reservoir for nearly 40 years, there have been no evaluations on the influence of …

Identification Of Carbohydrate Gene Clusters Obtained From In Vitro Fermentations As Predictive Biomarkers Of Prebiotic Responses, Car Reen Kok, Devin J. Rose, Juan Cui, Lisa Whisenhunt, Robert Hutkins

Department of Food Science and Technology: Faculty Publications

Background Prebiotic fibers are non-digestible substrates that modulate the gut microbiome by promoting expansion of microbes having the genetic and physiological potential to utilize those molecules. Although several prebiotic substrates have been consistently shown to provide health benefits in human clinical trials, responder and non-responder phenotypes are often reported. These observations had led to interest in identifying, a priori, prebiotic responders and non-responders as a basis for personalized nutrition. In this study, we conducted in vitro fecal enrichments and applied shotgun metagenomics and machine learning tools to identify microbial gene signatures from adult subjects that could be used to predict …