Life Sciences Commons^™

Bio-Inspired Airfoil Design Based On The Aerodynamic Analysis Of A Bird Feather Microstructure, Jack C. Ihm

College of Graduate Studies: Theses & Dissertations

This study investigates the aerodynamic effects of a bio-inspired airfoil design based on the microstructure of a secondary feather from a female wood duck. The research hypothesized that incorporating barbs and barbules into an airfoil design would modify boundary layer behavior by introducing localized flow disturbances. To test this, a bio-inspired airfoil was developed by integrating the microstructure into a NACA 0012 airfoil and analyzed using computational fluid dynamics (CFD) simulations at angles of attack of 0°, 5°, 10°, and 15°. The results showed that the bio-inspired airfoil influenced boundary layer behavior, producing localized flow disturbances near x/c = 0.7 …

Variations Of Hex Bar Deadlifts On Post-Activation Performance Enhancement In Collegiate Baseball Athletes, Samuel Sanders

College of Graduate Studies: Theses & Dissertations

Single-session resistance priming protocols are used by strength and conditioning coaches to acutely improve neuromuscular mechanisms that are beneficial to athletic performance. This study aimed to examine if a concentric-only hex bar deadlift (CHBDL) would produce a similar post-activation performance enhancement (PAPE) effect as a full-range-of-motion hex bar deadlift (THBDL) and mitigate perceived measures of fatigue and soreness in collegiate athletes. 19 NCAA Division I baseball athletes completed the study. A repeated measures design with randomized assignment and counterbalanced order was utilized. Over two weeks, the CHBDL and THBDL were added into a typical priming protocol used by the team’s …

Survey And Identification Of Entomopathogenic Fungi In Millipede Species In Coastal Georgia, Kristin L. Campbell Bailey

College of Graduate Studies: Theses & Dissertations

Entomopathogenic fungi are well-known, species-specific pathogens of a wide diversity of insects that infect, manipulate, and kill their insect hosts to complete their life cycle. Recently in Savannah, Georgia, millipedes belonging to the genus Eurymerodesmus were observed exhibiting pre-death climbing behaviors associated with pathogenic fungal infection. Dying millipedes summited vegetation and subsequently died in elevated positions along edge habitat transitioning a recreational field and forest. Upon inspection, fungal structures found emerging from dead millipedes anatomically resembled Arthrophaga myriapodina, which is the first documented entomophthoralean fungus to infect millipedes. The goal of this research was to obtain species-level identification of the …

Evaluating Impacts Of Footpaths On Resiliency Of Restored Dunes At Tybee Island, Georgia, Skyler J. Fox

College of Graduate Studies: Theses & Dissertations

Sand dunes provide critical ecosystem services including storm protection by acting as natural barriers. However, these systems are threatened by human disturbance, particularly pedestrian traffic occurring at footpaths that damages dune vegetation. Vegetation is essential to dune growth and stability, as dune plants trap and bind sand. When trampled, dunes become more vulnerable to erosion and less effective at providing coastal protection. On Tybee Island, Georgia—a popular tourist destination—a vegetated dune was constructed in 2020 to enhance storm protection. This study assessed how footpaths impact dune resiliency and aimed to inform management strategies. I evaluated: (1) how characteristics of vegetation, …

Assessment And Health Benefit Of Vitamin C Using A549 Cell, Yetunde Adepoju

College of Graduate Studies: Theses & Dissertations

Vitamin C (ascorbic acid) is a vital micronutrient recognized for its antioxidant capacity and essential bodily functions, such as collagen formation, neurotransmitter activity, and regulation of the immune system. This study explores how vitamin C can protect and potentially heal cells under oxidative stress and inflammation, using A549 cells, a human lung epithelial cell line, as the model system. The cells were exposed to varying concentrations of vitamin C dissolved in water, DMSO, and 5% DMSO. To assess the outcome, cell viability was measured with an MTT assay. In addition, the expression of key genes related to oxidative stress and …

The Bacteriostatic, Regenerative, And Immunomodulatory Properties Of Extracellular Matrix Particles For Lung Injury, Keera P. Rhoads

Theses and Dissertations

Acute respiratory distress syndrome (ARDS) is a prevalent, life-threatening lung condition, affecting nearly 200,000 Americans annually, with a 40% international mortality rate. There is no cure for ARDS, and current pharmacological treatments have limited effectiveness. Symptoms can be mitigated with mechanical ventilation, though this often leads to ventilator-induced lung injuries (VILI) and puts critically ill patients at risk of infections, including ventilator-associated pneumonia (VAP). A promising therapeutic is the extracellular matrix (ECM), a complex network of structural proteins and bioactive molecules that has been shown to have anti-inflammatory properties and prevent fibrosis. We aim to utilize the regenerative and immunomodulatory …

Enhancing Clinical Trial Matching In Molecular Diagnostics: Using Natural Language Processing And Clustering Approaches In Hematological Malignancies, Gillian Fanning

Theses and Dissertations

Clinical trial matching is a critical component of personalized medicine, particularly in the management of hematologic malignancies. At Virginia Commonwealth University (VCU) Health, the Molecular Diagnostics (MDX) Lab produces somatic variant reports and recommends clinical trials based on the presence of clinically significant mutations. However, the current manual trial recommendation process is time-intensive and lacks scalability.

This study introduces a computational framework to streamline and standardize clinical trial matching using natural language processing (NLP) and unsupervised clustering. Trial brief descriptions were analyzed to extract frequent terms, and trials were grouped based on term similarity using joint dimensionality reduction and clustering. …

Dickkopf1(Dkk1): A Novel Endogenous Ligand To Prime Nlrp3 Inflammasome Via Tlr4, Theingi Aung

Theses and Dissertations

Dickkopf1(DKK1) is a quintessential Wnt antagonist and immunomodulator in various inflammatory diseases. The underlying molecular mechanisms of DKK1-mediated immunomodulation remain elusive. Here, we identified TLR4 as a new receptor for DKK1 to activate NFκΒ pathway-mediated gene expression and pyroptosis via NLRP3 inflammasome in human and mouse macrophages.

DKK1 employed TLR4 to initiate NFκB signaling cascade via MyD88. MyD88-TAK1-NFκΒ pathway activation by DKK1 increased HIF1α, NFκB, and NLRP3 protein expression levels, leading to pyroptosis. Unlike LPS, DKK1 did not induce IRAK4 phosphorylation, while the interaction between MyD88 and IRAK4 was maintained for downstream signaling activation. DKK1 did not induce IRF3 phosphorylation …

Comparative Study Of Single Imputation Techniques For The Prediction Of Missing Dairy Data, Ahmed M. Gad Prof, Ahmed Abdelhakim Ahmed Mr, Eman Manaa Prof, Basant Shafik Dr, Sakr Mostafa Prof

Business Administration

Dairy farm records are a crucial component of effective livestock business management. Record analysis allows a farm’s owner to make informed decisions. Incomplete records are less useful for data analysis, so it's important to handle missing values correctly. This study compares different imputation methods for handling missing values in a dataset of dairy records comprising 997 records collected from 234 cows between 2012 and 2022. The dataset was screened against records with missing values and then deleted, resulting in 858 observations from 200 animals. There were missing values in two variables, with a missing percentage of 13.9%: days in milk …

Helminth Parasites Of Galápagos Mammals: A New Cestode Of The Genus Raillietina From The Endemic Rice Rat Nesoryzomys Swarthi And A Summary Of Parasites From Both Endemic And Invasive Rodents, Scott Lyell Gardner, Emma K. Chesley, Michael C. Friedle, Altangerel Tsogtsaikhan Dursahinhan

Scott L. Gardner Publications

In this first report of endoparasites from endemic land-mammals of the Galápagos Islands, we describe a new species of cestode of the genus Raillietina (Cyclophyllidea: Davaineidae) from a species of Nesoryzomys and summarize the extent of helminth parasitism in both oryzomyine endemics and introduced species of Rattus. Up to the current time, no helminth parasites have been reported from rodents of the Galápagos, and little work has yet been done describing and synthesizing Galápagos parasite diversity. In historical times, several species of autochthonous rodents have occupied the islands including: Nesoryzomys narboroughi Heller 1904, N. fernandinae Hutterer and Hirsch …

Zoysiagrass Tolerance To Selective Herbicides For The Removal Of Bermudagrass And The Distribution Of The Annual Bluegrass Weevil (Listronotus Maculicollis) In Kentucky, Kenneth D. Clayton

Theses and Dissertations--Plant and Soil Sciences

Bermudagrass (Cynodon dactylon) may be a problematic weed within zoysiagrass (Zoysia spp.) swards across its entire range. The objective of this study was to determine the efficacy of the herbicide safener metcamifen + trifloxysulfuron-sodium, in conjunction with fluazifop-P-butyl, at removing bermudagrass from zoysiagrass and how varying levels of treatment affected bermudagrass control and zoysiagrass tolerance. Field studies tested rates of metcamifen + trifloxysulfuron-sodium applied with fluazifop-P-butyl compared to treatments of fluazifop alone and fenoxaprop with triclopyr. All treatments controlled bermudagrass, and treatments with the herbicide safener remained under the 20% injury threshold for zoysiagrass for ≤ to 15 days compared …

Fusarium Head Blight Resistance Genes Impact Agronomic Performance, Flavor, Milling, And Baking Traits In Soft Red Winter Wheat, Joyce Morris

Theses and Dissertations--Plant and Soil Sciences

Fusarium Head Blight (FHB) is an economically devastating disease of wheat (Triticum aestivum L.) causing low yields and poor quality. FHB, caused by Fusarium graminearum, disrupts the grain filling phase and results in bleached spikes and shriveled seeds. Deoxynivalenol (DON) is a mycotoxin produced by the fungal pathogen when it infects the plant; DON is harmful when consumed by humans and causes feed rejection in livestock. Using FHB resistant varieties and timely applications of fungicides is the optimum strategy for management of this disease. However, there has been little research focusing on the impact of FHB resistance genes …

Advancing Root Trait Measurements For A Deeper Understanding Of Soil Biogeochemistry, Brian Rinehart

Theses and Dissertations--Plant and Soil Sciences

Climate change is disrupting (agro)ecosystems, with the potential for significant losses in crop productivity and ecosystem resilience due to changes in water and biogeochemical cycling. These disruptions can also release more carbon dioxide into the atmosphere through the degradation of soil organic matter. Plant roots have emerged as a potential tool for mitigating these effects, given their roles in plant function and in driving soil biogeochemistry. While this interest is growing, our ability to implement root trait selection is limited due to constraints on characterizing roots and limited clarity on the effects of traits on plant and ecosystem function. My …

Influence Of Industrial Hemp On Soil Health Parameters In A Kentucky Cropping System, Jack T. Eaker

Theses and Dissertations--Plant and Soil Sciences

Industrial hemp (fiber, floral, and grain: Cannabis sativa L.) legalization has prompted research into its incorporation into agronomic rotations and impacts on agroecosystem services such as nutrient dynamics. This study quantified the effects of integrating grain and fiber hemp on soil health, hypothesizing hemp would positively impact soil health due to its taproot, reported C benefits, and nutrient requirements. Conducted in Kentucky at two locations, a completely randomized block design included six crop rotation treatments, with soil cores collected at initiation (2020) and post three growing seasons (2023). Soil parameters analyzed included particulate organic matter, short-term CO2 mineralization, water-extractable organic …

Revolutionizing Grapevine Breeding Programs: A Mobile Genome Editing System For Perennial Crops, Bridget Bolt

Theses and Dissertations--Plant and Soil Sciences

Grapevine (Vitis vinifera) faces unprecedented challenges from climate change, with up to 90% of current growing regions potentially becoming unsuitable for production within decades. Traditional breeding approaches require 25-30 years for variety development, creating a time constraint incompatible with the pace of environmental change. This research establishes the approach for a novel mobile RNA-based gene editing platform that addresses longstanding bottlenecks in grapevine improvement while preserving cultivar identity and reducing breeding timelines.

This research developed a three-component system for transgene-free gene editing in grapevine. First, a mobile CRISPR/Cas9 system was established using Agrobacterium rhizogenes transformation and the cut-and-dip …

Exploring The Role Of Living Roots In Soil Organic Matter Dynamics, Sharmin Akther

Theses and Dissertations--Plant and Soil Sciences

Roots play a central role in soil organic matter (SOM) formation, yet the contributions of living roots compared with root- and shoot-derived litter remain incompletely understood across systems and management contexts. This thesis combines a global meta-analysis with a two-year field experiment to evaluate how continuous living root activity shapes soil organic carbon (SOC) dynamics. The meta-analysis synthesized 21 studies (57 observations) comparing cropping systems with enhanced living root continuity to systems with fallow periods or annual-only rotations. Perennial and continuous cropping systems increased annual C inputs and SOC stocks relative to controls, but their SOC sequestration efficiency declined because …

Letters From The Professors

Scientific Kenyon: The Neuroscience Edition

No abstract provided.

Table Of Contents

Scientific Kenyon: The Neuroscience Edition

No abstract provided.

#Obsessed Get Ready With Me: A Day In The Life With Ocd, Jordan Herrera

Scientific Kenyon: The Neuroscience Edition

No abstract provided.

Scientific Kenyon: Neuroscience Edition (Full Issue)

Scientific Kenyon: The Neuroscience Edition

No abstract provided.

Can I Actually Write This? Neuroscience Of Self-Doubt And Anxiety, Issachar Lopez

Scientific Kenyon: The Neuroscience Edition

No abstract provided.

Dissociative Amnesia: Why Our Brains Make Us Forget, Ruby Hutchins

Scientific Kenyon: The Neuroscience Edition

No abstract provided.

Through Rose-Colored Lenses: How Color Perception Shapes Our Daily Lives, Ronan Daly

Scientific Kenyon: The Neuroscience Edition

No abstract provided.

Pain, Pain, Go Away!, Jolien Kusi

Scientific Kenyon: The Neuroscience Edition

No abstract provided.

You're A Legacy! Understanding Intergenerational Trauma And Epigenetics, Kiersten Hoffmann

Scientific Kenyon: The Neuroscience Edition

No abstract provided.

A Jiggle To Help The Wiggle, Juliette Lowe

Scientific Kenyon: The Neuroscience Edition

No abstract provided.

Forget The All-Nighter: How Sleep Boosts Memory Consolidation, Paula Sorić

Scientific Kenyon: The Neuroscience Edition

No abstract provided.

Kenyon College Neuroscience Department Faculty And Staff

Scientific Kenyon: The Neuroscience Edition

No abstract provided.

Scalable Machine Learning Framework For Adaptive Irrigation Management Of Maize And Soybean In The U.S. Midwest, Precious N. Amori, Derek M. Heeren, Yeyin Shi, Eric Wilkening, Ivo Z. Goncalves, Guillermo R. Balboa, Daran R. Rudnick, Abia Katimbo, Randall S. Ritzema

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Conventional soil water balance (SWB) irrigation scheduling tools, such as FAO-56-based Spreadsheets and the Spatial Evapotranspiration Modeling Interface (SETMI), rely heavily on manual inputs and periodic field measurements, leading to delayed recommendations and missed opportunities to prevent crop stress. More critically, these tools lack the computational scalability and adaptability to leverage the high-frequency, high-volume datasets now available through modern sensing technologies. As precision irrigation increasingly depends on integrating spatially and temporally nuanced field information, there is a pressing need for decision-support systems that can process Big Data efficiently and respond in real-time. To overcome these limitations, we developed and validated …

Évaluation Et Caractérisation De L'Exposition Aux Fumées De Soudage Et Leurs Composantes Métalliques Lors D'Activités De Soudage Au Québec, Michèle Bouchard, Jairo Buitrago-Cortes, Naïma El Majidi, Jonathan Côté, Denis Dieme, Marc Mantha, Philippe Sarazin, Capucine Ouellet, Loïc Wingert

Rapports de recherche scientifique

Problématique et objectifs :

Les fumées de soudage sont classées comme cancérogènes chez l’humain et sont associées à un risque accru de plusieurs autres effets sur la santé des soudeurs. L’objectif général de cette recherche était d’établir la nature et le niveau d’exposition aux composantes métalliques lors d'activités de soudage chez des apprentis soudeurs au Québec, en effectuant des mesures dans différentes matrices biologiques et dans l’air lors d’un suivi longitudinal.

Méthode :Cette recherche a été réalisée dans des écoles d'apprentis soudeurs de la région de Montréal, où les techniques de soudage les plus courantes sont utilisées. Elle a …