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Articles 18091 - 18120 of 256002
Full-Text Articles in Life Sciences
Can Organs Be Generated From A Patient’S Own Stem Cells?, David Heimowitz
Can Organs Be Generated From A Patient’S Own Stem Cells?, David Heimowitz
The Science Journal of the Lander College of Arts and Sciences
The global shortage of transplantable organs represents a critical medical challenge, with current organ donation systems meeting less than 10% of the worldwide need. This situation has spurred intensive research into regenerative medicine, particularly focusing on the potential of generating organs from a patient’s own stem cells. This review examines the current state of stem cell research and its applications in organ generation, analyzing both the progress made and the challenges that remain. Through a comprehensive analysis of recent literature and clinical trials, the study explores the fundamental principles of stem cell biology, current therapeutic applications, and the role of …
Implant Alternatives: The Advancements Of Stem Cells In Regenerative Dentistry, Akiva Goldschmidt
Implant Alternatives: The Advancements Of Stem Cells In Regenerative Dentistry, Akiva Goldschmidt
The Science Journal of the Lander College of Arts and Sciences
This research paper explores the potential of mesenchymal stem cells (MSCs) within the realm of dentistry, focusing particularly on their ability to repair tissues and regenerate entire teeth. MSCs are significant as they can send differentiation signals to nearby cells and release growth factors such as TGF-β and VEGF, which promote cellular activities necessary for dental repair and regeneration. The paper discusses the traditional methods of dental restoration, such as fillings and implants, and their inherent limitations. It then transitions to exploring innovative strategies that utilize MSCs to overcome these challenges and regenerate tooth structures including enamel, dentin, and periodontal …
Retinal Vision Restoration, Aharon S. Galandauer
Retinal Vision Restoration, Aharon S. Galandauer
The Science Journal of the Lander College of Arts and Sciences
Retinal degeneration is a leading cause of vision loss worldwide due to the retina’s inability to regenerate specialized cells after injury or stress. This study examines the potential for retinal regeneration by assessing current research on Müller glial cell differentiation and stem cell-based treatments. An analysis of experimental studies and therapeutic advancements highlights the mechanisms observed in regenerative models such as zebrafish and chicks, in contrast to the reactive gliosis and glial scarring observed in humans. Findings suggest that therapies such as optogenetics and stem cell transplantation have partially restored vision; however, their limitations stem from an inability to fully …
Can Cystic Fibrosis Be Treated With Genetic Therapy?, Steve Silverberg
Can Cystic Fibrosis Be Treated With Genetic Therapy?, Steve Silverberg
The Science Journal of the Lander College of Arts and Sciences
This paper discusses the current and prospective treatment options for the fatal genetic disease cystic fibrosis. Cystic fibrosis (CF) is a rare recessive genetic disorder that is caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which codes for a protein that is on the surface of a cell. This protein allows for the flow of chloride, bicarbonate, and sodium ions to pass through the cell wall, bringing water with it. When this protein doesn’t work, the lack of ions and water in extracellular fluid becomes too thick, causing a multitude of problems. The most common …
Risk Factors Of Covid-19 Mortality, Ellie Wolff
Risk Factors Of Covid-19 Mortality, Ellie Wolff
The Science Journal of the Lander College of Arts and Sciences
This paper investigates the relationship between key health demographics and COVID-19 mortality while focusing on identifying both physiological and genetic factors that contribute to variations in mortality rates. Specifically, it examines how pre-existing conditions—such as sex, autoimmune disorders, cardiovascular diseases, and obesity—interact with COVID-19 pathophysiology to influence patient outcomes. While previous research has highlighted demographic disparities in hospital mortality rates, this study aims to establish a causal, mechanistic link between these health factors and COVID-19 severity. Methods to extract and analyze data included literature review using existing studies such as peer-reviewed articles and reports from PubMed, CDC, etc. By analyzing …
The Bidirectional Gut-Brain Axis: Impact Of Dysbiosis On Depression Through The Hpa Axis, Matan Shiller
The Bidirectional Gut-Brain Axis: Impact Of Dysbiosis On Depression Through The Hpa Axis, Matan Shiller
The Science Journal of the Lander College of Arts and Sciences
Emerging research suggests that depression is not solely a brain disorder but is deeply influenced by the gut microbiome. The gut-brain axis (GBA) is a bidirectional communication system linking the gastrointestinal system and the brain, modulating mood, behavior, and mental health. Gut microbiota produce metabolites, such as short-chain fatty acids (SCFAs) and tryptophan catabolites, that influence neurotransmission and the stress response via the hypothalamic-pituitary-adrenal (HPA) axis. Dysbiosis, or microbial imbalance, disrupts these pathways, contributing to a major depressive disorder (MDD). Evidence from germ-free animal studies and fecal microbiota transplants (FMT) highlights the role of gut microbiota in emotional regulation and …
Citizen’S Rare Plant Watch, Nora Dunkirk, Gabriel Campbell, Kris Freitag
Citizen’S Rare Plant Watch, Nora Dunkirk, Gabriel Campbell, Kris Freitag
Rae Selling Berry Seed Bank and Plant Conservation Program
Rare species data for plants is lacking, hindering land management decisions and conservation outcomes. With Citizen's Rare Plant Watch, we empower citizen scientists to provide the “eyes on the ground” and collect data needed for conservation decision making in Oregon.
The Detection Of Multiple Human Papillomavirus (Hpv) Types Through The Development Of An Isothermal Dna Amplification Assay, Lauren Powell
The Detection Of Multiple Human Papillomavirus (Hpv) Types Through The Development Of An Isothermal Dna Amplification Assay, Lauren Powell
Doctoral
Human Papillomaviruses (HPV) belong to the Papillomaviridae family, with over 200 known types classified into high-risk (HR-HPV) and low-risk (LR-HPV) groups based on their carcinogenic potential. While most HPV infections are asymptomatic and transient, persistent infection can lead to health issues, including cervical cancer. Given the high prevalence of HPV and its potential for malignant transformation, nucleic acid amplification assays have become a widely implemented tool for routine HPV testing. This study developed a real-time isothermal DNA amplification assay for the detection and differentiation of multiple HPV types. A universal primer set was designed to target a highly conserved region …
Foreign Object Detection System Development Using Edge Devices Integrated With Quadcopter Autonomous Tracking, Chi-Chia Huang, Ching-Hung Lee
Foreign Object Detection System Development Using Edge Devices Integrated With Quadcopter Autonomous Tracking, Chi-Chia Huang, Ching-Hung Lee
Journal of Marine Science and Technology–Taiwan
This study proposes an all-weather autonomous foreign-object detection system capable of operating in low-light environments. We used a highly mobile quadcopter equipped with an edge-computing device as the inspection platform. On the software side, we integrated a low-light image enhancement model, a path-tracking algorithm, and a foreign object detection model to achieve rapid object detection. A lightweight, low-light image-enhancement model reduces the need for additional lighting equipment, thereby enabling reliable detection under low-light conditions. The path-tracking algorithm integrates a lightweight semantic segmentation model with traditional image-processing techniques to establish flight paths efficiently and reliably. The foreign-object detection component employs state-of-the-art …
Optimization Of Underactuated Ship Sliding Mode Controller Based On The Ddpg Algorithm, Lin Ma, Mingzhe Qi, Shicai Chen, Hongwei Bian, Jian Zhang
Optimization Of Underactuated Ship Sliding Mode Controller Based On The Ddpg Algorithm, Lin Ma, Mingzhe Qi, Shicai Chen, Hongwei Bian, Jian Zhang
Journal of Marine Science and Technology–Taiwan
Due to the development of ship intelligence, the demand for precise controllers is increasing day by day. In traditional design, the trial-and-error method often leads to the use of inaccurate controller parameters, causing oscillations when environmental disturbances are present. To address these issues, this study introduces deep learning to optimize the controller parameters, particularly those used for sliding mode controllers in underactuated ships. We adopt the Deep Deterministic Policy Gradient (DDPG) algorithm based on the Actor Critic framework. By freely setting the reward function to match the control objective, the trained model can output more accurate controller parameters, with the …
Experiments On Aluminum Alloy Additive Layer Waam Lamination Using The Arc Current Reduction Technique, Jukkapun Greebmalai, Eakkachai Warinsiriruk, Chao-Hsiang Hsiao, Yin-Tien Wang
Experiments On Aluminum Alloy Additive Layer Waam Lamination Using The Arc Current Reduction Technique, Jukkapun Greebmalai, Eakkachai Warinsiriruk, Chao-Hsiang Hsiao, Yin-Tien Wang
Journal of Marine Science and Technology–Taiwan
Recent advancements in additive manufacturing have been propelled by innovations in processes, materials, and fabrication techniques. This study specifically focuses on the optimizing Wire and Arc Additive Manufacturing (WAAM) within the Gas Metal Arc Welding (GMAW) process. The goal is to build laminated layers using aluminum alloy from the five-thousand series. In this research, a novel technique is introduced that employs a reduced arc-current during the additive layer progress for aluminum alloys, along with a double pulse current in the GMAW process to enhance weldability. The material used for addition is ER5356 aluminum wire, which is applied to an Al-5083 …
An Optimization Model For Supporting Bunkering Decisions In Bulk Shipping, Chung-Cheng Lu, Hui-Chieh Li, Hung-Yu Chen
An Optimization Model For Supporting Bunkering Decisions In Bulk Shipping, Chung-Cheng Lu, Hui-Chieh Li, Hung-Yu Chen
Journal of Marine Science and Technology–Taiwan
This study addresses a bunkering optimization problem for bulk shipping carriers that explores route deviation to find optimal bunkering locations and amounts. A mixed integer linear programming (MILP) model is developed to determine optimal bunkering decisions that minimize total operating costs, including total daily operating costs, bunkering costs, port charges and surcharges, while observing time window constraints at loading/unloading ports. The proposed model is evaluated using instances generated from real data provided by H company with its operational headquarters in Taipei, Taiwan, which operates a fleet of handysize ships in East and South Asia. The results indicate that optimization models …
Assessment Of Coastal Navigation Safety: A Case Study Of Boka Bay With Stakeholder Perspectives, Ivan Mraković, Rino Bošnjak
Assessment Of Coastal Navigation Safety: A Case Study Of Boka Bay With Stakeholder Perspectives, Ivan Mraković, Rino Bošnjak
Journal of Marine Science and Technology–Taiwan
The navigational safety of Boka Bay, i.e., a critical maritime area along the Adriatic coast, is of great importance owing to its ecological sensitivity, diverse marine traffic, and significant economic activity. This study provides a comprehensive assessment by analyzing the perspectives of various stakeholders, including seafarers, local pilots, skippers, regulatory authorities, and others engaged in maritime activities within the bay. Using a structured questionnaire survey, both quantitative and qualitative data were collected in formats such as descriptive responses, Yes/No choices, and Likert scale ratings, ensuring a well-rounded understanding of navigational practices and challenges. The data were analyzed using descriptive statistics, …
A Hybrid Model To Assess Commercial Port Resilience In Taiwan, Po-Hsing Tseng, James J.H. Liou
A Hybrid Model To Assess Commercial Port Resilience In Taiwan, Po-Hsing Tseng, James J.H. Liou
Journal of Marine Science and Technology–Taiwan
Since 2021, international commercial ports have faced unprecedented challenges (e.g., COVID-19 pandemic, Suez Canal congestion), impacting daily life, work, human well-being, properties, the environment, and socio-economic activities. The adaptation capability resilience of international commercial ports to respond to external changes has become crucial. This study develops an expert knowledge-based hybrid multi-criteria decision-making model integrating Best-Worst Method (BWM), Rough Dombi Aggregator, and Combined Compromise Solution (CoCoSo) to evaluate port resilience capabilities, using Taiwan's international commercial ports as a case study. We propose four evaluation dimensions encompassing 13 indicators: detection capability, resistance capability, resource integration capability, and recovery capability. The BWM determined …
An Evaluation Of The Possibility And Effectiveness Of Renewable Energy In Container Terminal At Jinhae New Port, Min-Seop Sim, Yul-Seong Kim, Chang-Hee Lee
An Evaluation Of The Possibility And Effectiveness Of Renewable Energy In Container Terminal At Jinhae New Port, Min-Seop Sim, Yul-Seong Kim, Chang-Hee Lee
Journal of Marine Science and Technology–Taiwan
The international goals of combating climate change and reducing greenhouse gas emissions are driving container terminal operators to adopt renewable energy solutions. This study evaluated the feasibility and effectiveness of introducing renewable energy and eco-fuels for energy independence at the Jinhae New Port Container Terminal, South Korea. Using portfolio analysis, eight renewable energy technologies (solar power, solar thermal energy, wind energy, hydropower, marine energy, geothermal energy, bioenergy, and waste-to-energy) and seven eco-friendly fuels (electricity, liquefied natural gas, liquefied petroleum gas, hydrogen fuel cells, ammonia fuel cells, bioenergy, and hybrid systems) were assessed. Survey data from stakeholders identified solar, wind, and …
Making Dew In The Atacama Desert: A Paradigmatic Case Of Plant Water Uptake From An Unsaturated Atmosphere Fails A Test, Jess T. Gersony, Anju Manandhar, Uri Hochberg, Nora Abdellaoui, Paula Llanos, Jacques Dumais, N. Michele Holbrook, Fulton E. Rockwell
Making Dew In The Atacama Desert: A Paradigmatic Case Of Plant Water Uptake From An Unsaturated Atmosphere Fails A Test, Jess T. Gersony, Anju Manandhar, Uri Hochberg, Nora Abdellaoui, Paula Llanos, Jacques Dumais, N. Michele Holbrook, Fulton E. Rockwell
Biological Sciences: Faculty Publications
No abstract provided.
Physiological And Genetic Studies Of Hydrotropism In The Maize Primary Root, Muyu Gu
Physiological And Genetic Studies Of Hydrotropism In The Maize Primary Root, Muyu Gu
Electronic Theses and Dissertations
No abstract provided.
Evaluating Dietary Consequences On Body Mass And Thermal Heat Flux Of North American Bison (Bison Bison) Yearling Heifers, Kendall Marie Wald
Evaluating Dietary Consequences On Body Mass And Thermal Heat Flux Of North American Bison (Bison Bison) Yearling Heifers, Kendall Marie Wald
Electronic Theses and Dissertations
No abstract provided.
Evaluating Effects Of Copper Sources In Nursery Pig Diets And Phytase Inclusion And Diet Interactions On Water Usage In Growing And Finishing Pigs, Daniel Rosales
Electronic Theses and Dissertations
In modern swine production, nutritional strategies that optimize growth performance, resource utilization, and carcass quality are essential. Three independent trials were conducted to evaluate how dietary modifications involving copper (Cu) sources, phytase inclusion, and amino acid reformulation affect nursery and grow-finish pigs. The first trial assessed the effects of three different Cu sources on nursery pig growth performance. A total of 1,145 pigs (5.9 ± 1.3 kg BW) were assigned to one of four dietary treatments: control, tri-basic Cu chloride source #1 (TBCC1), Cu chelate (cCu), or tri-basic Cu chloride source #2 (TBCC2), each providing 150 ppm of Cu. Over …
Deciphering Genetic Contributions To Antibiotic Persistence: Insights From Multi-Gene Knockout Studies, Elise K. Schweer
Deciphering Genetic Contributions To Antibiotic Persistence: Insights From Multi-Gene Knockout Studies, Elise K. Schweer
Electronic Theses and Dissertations
Antibiotic resistance is a critical global health challenge, complicating efforts to treat bacterial infections effectively. Antibiotic persistence plays a significant role in driving resistance. Persisters are a subpopulation of non-dividing bacterial cells that often evade lethal antibiotic treatment. Once antibiotics are removed, these cells "resurrect," resuming growth and may lead to relapsing infections. Notably, the progeny of persister cells exhibit a heightened tendency to acquire mutations or incorporate antibiotic resistance genes, further compounding the challenge of antibiotic resistance. In our recent study, we knocked out seven hypothetical genes and observed a significant reduction in persister levels. Compared to the wild …
Optimizing Heifer Development On Dormant Rangelands By Integrating Precision Livestock Technologies With The Range Supplementation Model And The Evaluation Of Short-Term Rotations Of Precision Technology On Plant Communities, Hadley Ann Dotts
Electronic Theses and Dissertations
Heifer development on dormant rangelands offers a cost-effective alternative to feedlot or drylot systems. However, traditional bunk supplementation methods often result in uneven intake, inefficient feed use, and ecological degradation around static feeding sites. This thesis evaluated the integration of precision livestock technologies and a dynamic Range Supplementation Model to improve individual animal performance, weight uniformity, and rangeland sustainability in extensive heifer development systems in the Northern Great Plains. The first study involved a seven-month trial (November 2023–May 2024) with 50 yearling Angus heifers grazing dormant native rangelands at the SDSU Cottonwood Field Station. Heifers were stratified into two treatments: …
Target Cell-Associated Cd47 Suppresses Nadph Oxidase Activity In Macrophages During Antibody Dependent Cellular Phagocytosis, Seuly Akter
Electronic Theses and Dissertations
CD47-SIRPα signaling is a well-known immune checkpoint that suppresses macrophage-mediated antibody-dependent cellular phagocytosis (ADCP). In this study, we explored how CD47 influences reactive oxygen species (ROS) production driven by Fcγ receptor (FcγR) signaling. Our results show that macrophages produce significantly more ROS when encountering IgG coated target cells lacking CD47.Polarization with IFNγ further amplified this effect. ThusCD47-SIRPα interactions limit phagocytosis and suppress oxidative ROS production by macrophages. We found that CD47 blockade and IFNγ stimulation enhanced ADCP through distinct mechanisms. CD47 blockade removed the inhibitory "don't eat me" signal supporting ADCP and ADROS. Similarly, IFNγ enhances ADCP by upregulating FcγRI …
Testing The Effect Of Source And Environment On Native Seed Germination To Inform Seed-Based Restoration Of Grasslands, Brandon Clark
Testing The Effect Of Source And Environment On Native Seed Germination To Inform Seed-Based Restoration Of Grasslands, Brandon Clark
Electronic Theses and Dissertations
Grasslands are one of the most endangered ecosystems on the planet, and they provide a variety of important ecosystem services that people rely on. Losses of grasslands can be mitigated through restoration. Seed-based restoration is a regularly used practice due to its practicality and cost-effectiveness. Planting non-local seed that may not be suitable for its destination environment can have consequences in plant establishment and subsequent restoration success. This experiment tested the response (final germination and germination rate) of seed from 11 perennial tallgrass species sourced from 3 different locations to different germination temperature conditions. Seeds from three sources of each …
Assessing Reproductive Health In Zoo-Managed African Elephant Bulls (Loxodonta Africana), Kaitlyn Marie Campbell
Assessing Reproductive Health In Zoo-Managed African Elephant Bulls (Loxodonta Africana), Kaitlyn Marie Campbell
Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–
Populations of zoo-managed African elephant (Loxodonta Africana) exhibit substantial individual- and population-level variation in reproductive success, yet research has largely focused on females, leaving male fertility poorly understood. Subfertility in bulls, characterized by low libido and inconsistent semen quality, poses significant challenges to genetic management and long-term population sustainability. This study a) systematically evaluates semen quality, b) identifies physiological, behavioral, social, and environmental determinants of fertility, and c) advances ex situ conservation through the expansion of the African elephant sperm bank. Between January 2023 and July 2025, 209 semen collection events were conducted from 13 sexually mature bulls …
Leaf-Based Varietal Categorization Of Sweetpotato (Ipomoea Batatas L. Lam.), A Potentially Healthful Vegetable, Using Image Processing And K-Means Clustering, Shahidul Islam, Md Towfiqur Rahman, Md Hamidul Rahman, Abdul Momin
Leaf-Based Varietal Categorization Of Sweetpotato (Ipomoea Batatas L. Lam.), A Potentially Healthful Vegetable, Using Image Processing And K-Means Clustering, Shahidul Islam, Md Towfiqur Rahman, Md Hamidul Rahman, Abdul Momin
Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research
Sweetpotato (Ipomoea batatas Lam) leaves contain higher concentrations of phenolic compounds, flavonoids, and carotenoids that are remarkable in health promotion. However, the nutrient content in sweetpotato leaves varies from variety to variety, and leaf shape and color are the key identifying factors for the varietal classification of sweetpotatoes. So, detecting sweetpotato leaves is essential for the in-situ identification of sweetpotato varieties and for developing intelligent agricultural systems. This study aimed to create a leaf-shape-based varietal classification technique for sweetpotato using image processing techniques coupled with a K-means clustering algorithm. 38 leaf images (RGB) of two sweetpotato cultivars were collected …
In-Season Nitrogen Mmanagement: Leveraging Data Visualization For Precision Agriculture, Chathurika Harshani Narayana
In-Season Nitrogen Mmanagement: Leveraging Data Visualization For Precision Agriculture, Chathurika Harshani Narayana
Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research
Effective nitrogen management is vital for sustainable agriculture, impacting both crop yield and environmental health. Traditional methods often use fixed application rates set before planting, which do not adapt to changing crop needs during the season. This can lead to over- or under-application, reducing efficiency and sustainability. While modern tools like sensors, satellites, and UAVs provide valuable real-time data on crop and field conditions, integrating and using this data to guide timely nitrogen decisions remains a major challenge. In-season nitrogen management offers a solution by allowing for dynamic adjustments to nitrogen applications, addressing crop needs as they arise. This approach …
Effects Of Pubertal Stress On Later Pup-Directed Behavior In Pregnant And Non-Pregnant Adult Female Mice, Marissa Marylin Nicodemus
Effects Of Pubertal Stress On Later Pup-Directed Behavior In Pregnant And Non-Pregnant Adult Female Mice, Marissa Marylin Nicodemus
Graduate Theses, Dissertations, and Problem Reports (ETD)
Beginning in adolescence and throughout adulthood, women are at an increased risk for anxiety and mood disorders compared to men. Several risk factors for these disorders have been identified, but it is not clear how they interact. One such factor is pregnancy. The normative changes to the brain and behavior that occur during and after pregnancy are associated with an increased risk for anxiety and mood disorders. Exposure to adverse childhood experiences (ACEs) has also been associated with an increased risk of mood disorders, and compared to men, women appear to be particularly vulnerable to the lasting effects of stress …
Neural And Computational Approach To Understanding Environmental Modulation Of Behavioral Identity In Zebrafish, John W. Hageter
Neural And Computational Approach To Understanding Environmental Modulation Of Behavioral Identity In Zebrafish, John W. Hageter
Graduate Theses, Dissertations, and Problem Reports (ETD)
Organisms rely on behavior for survival. Animals engage in behaviors that allow for feeding, mating, exploring and navigating their environment among others. Necessary for these behaviors to develop are the environmental factors and underlying circuitry which make behavior possible. Specifically, how the environment guides underlying neural circuitry to develop unique facets or phenotypes of a larger behavior are key to understanding why unique behaviors exist. In this thesis, I build foundational evidence for determining these mechanisms through the use of the zebrafish local search behavior. This is a behavior that zebrafish employ following the loss of environmental illumination where they …
A Framework For Biomimetic Robot Design Applied To The Development Of A Robotic Model Of Drosophila Melanogaster, Clarissa A. Goldsmith
A Framework For Biomimetic Robot Design Applied To The Development Of A Robotic Model Of Drosophila Melanogaster, Clarissa A. Goldsmith
Graduate Theses, Dissertations, and Problem Reports (ETD)
For decades, the field of biologically inspired robotics has leveraged insights from animal locomotion to improve the walking ability of legged robots. Recently, “biomimetic” robots have been developed to model how specific animals walk. By prioritizing biological accuracy to the target organism rather than the application of general principles from biology, these robots can be used to develop detailed biological hypotheses for animal experiments, ultimately improving our understanding of the biological control of legs while improving technical solutions. Much of this work involves biologically inspired walking controllers informed by the morphology and dynamics of the insect nervous system, which necessitate …
Comparison Of Compositional Characteristics Of Protein Extracted From Spent Hemp Seed Cakes By One-Step Defatting With Organic Solvents Followed By Isoelectric Solubilization Precipitation Using Strong And Weak Acids, Miah Nicole Gathman
Graduate Theses, Dissertations, and Problem Reports (ETD)
Hemp seed cakes (HSC) are the byproduct of pressing hemp seeds for oil and are a significant agricultural waste product, with hundreds of tons produced annually. These nutrient-rich cakes have potential for sustainable applications in animal feed and food products. However, they could offer even greater value to the food industry through further extraction of the lipids and separation of the proteins they contain. Protein is a key nutritional component and companies are seeking cost-effective, time-efficient processes to concentrate protein from underutilized resources like HSC. Hexane (HEX) is a common solvent used in one-step defatting processes but may cause issue …