Life Sciences Commons^™

The Effect Of Gibberellins On Dwarf Millet Growth, Rylee Deckard, Reed Morrison, Chase Christopher, Amy Brice, Sanduni Galbokka Hewa, Malina Roberson, Matthew Palmer

2025 Student Academic Showcase

Dwarf and semidwarf variants of agricultural plants are used to decrease lodging without decreasing crop yield. Some dwarf genotypes lack the ability to produce the growth hormone gibberellin, and others lack complete receptor pathways. Exogenous gibberellic acid (GA) was applied to four dwarf millet genotypes over the course of six weeks to determine what pathway for dwarfism each dwarf genotype was. Statistical analysis was done to analyze the relationship between GA applications and increased plant growth. It was found that all genotypes had some response to the treatment, though some were more extreme than others. Additionally, the treatment group had …

Physical Attributes Of Competitive Collegiate Co-Ed Men, Base/Backspots, Flyers, And Tumblers, Grace M. Liebhart, Harry P. Cintineo

2025 Student Academic Showcase

Cheerleading is a demanding sport often overlooked in research. This study examined physical attributes of 41 collegiate cheerleaders representing co-ed men, base/backspots, flyers, and tumblers. Participants underwent body composition, relative countermovement and squat jump, isometric mid-thigh pull, and 1RM seated military press assessments. Data were analyzed using ANOVA with gender adjustment followed by Bonferroni-adjusted post-hoc tests (α=0.05). Analyses showed significant positional differences for body fat percentage (P< 0.003), lean mass (P< 0.001), squat jump (P=0.034), and 1RM strength (P< 0.001). Bases/backspots had higher body fat percentage than flyers (P=0.016) with no other differences (P>0.110). Lean mass and 1RM strength were highest in co-ed men (P< 0.018) followed by bases/backspots and tumblers than flyers (P< 0.073). Post-hoc analysis revealed no differences in squat jump (P>0.052). These findings highlight unique physical characteristics of cheerleading positions and suggest implementation of specific strength training programs. Future investigations should …

The Application Of Gibberellin On Dwarf Mutant Millet Plant (Setaria Viridis), Catherine Philipps, Desirae Snyder, Elizabeth Dill, Joselyn Wood, Kaneez Moughal, Katherine Kellner, Rachel Wilson

2025 Student Academic Showcase

Gibberellin is a hormone found in many plants whose purpose is to promote the growth of stems and leaves. The application of gibberellin in differing concentrations was applied to different strains of dwarf mutant millet plants and was compared to a control of nonmutant wild-type millet plants. After the initial sprouting of each seed, 4 different concentrations of gibberellin: 0g gibberellin/1L water, 0.02g/L, 0.05g/L, and 0.15g/L, were applied to the stem of each plant. A regression analysis was performed on the heights of each plant to determine the effectiveness of the varying gibberellin concentrations on the growth of millet plants. …

Maintenance Of Anaerobic Power Across A Competitive Season In Collegiate Women’S Ice Hockey Playersquinn, Quinn M. Mclaren, Olivia J. Grabianowski, Molly K. Henderson, Kyle Sunderland

2025 Student Academic Showcase

The purpose of this study was to examine changes in anaerobic power and capacity in women’s college ice hockey players from pre-season to post-season. Fourteen NCAA Division I female ice hockey players performed a 30-second Wingate test (WAnT) two weeks prior to the start of the competitive season and three weeks following the final game. Athletes completed a standardized warm-up including a short sprint on the cycle ergometer to prepare for the maximal effort test. The WAnT began from a rolling start, with the athlete pedaling at 100–110 RPM. Athletes then completed a 30-second all-out sprint against 9% body weight …

Adverse Cognitions: The Impact Of Childhood Trauma On Brain Development, Faith Salamone

2025 Student Academic Showcase

The effect of adverse experiences in childhood have been known to create lasting difficulties, even in adulthood. While it can be hard to determine the effects of childhood trauma on the brain, many studies have identified areas that appear to be negatively impacted by these adverse childhood experiences. This paper is a meta-analysis of eight articles that have attempted to investigate the effects of childhood trauma on the developing brain. These articles are specifically investigating the effects of childhood physical and/or sexual abuse. The areas that will be discussed in this paper are the prefrontal cortex, corpus callosum, the limbic …

Relationship Between Nutrition Knowledge And Body Composition Changes Across A Season In Collegiate Women’S Soccer, Emily M. Mowbray, Harry P. Cintineo, Kyle Sunderland

2025 Student Academic Showcase

PURPOSE: To determine the relationship between athlete preseason nutrition knowledge and changes in body composition over a competition season. METHODS: Twenty NCAA Division I women’s soccer athletes (20 ± 2 y, 167.8 ± 6.5 cm, 64.4 ± 7.2 kg) participated. Before fall training, athletes completed the Abridged Nutrition for Sport Knowledge Questionnaire (A-NSKQ) to assess nutrition knowledge. Body composition was assessed via dual-energy X-ray absorptiometry (DEXA) pre-season and one week post-season. Spearman's rank correlations examined relationships between A-NSKQ scores and DEXAderived measures (α = 0.05). RESULTS: Total A-NSKQ score showed a significant positive correlation with change in % body fat …

Dietary Preferences And Food-Seeking Behavior Of Discoid Cockroaches, Blaberus Discoidalis, Claire O'Brien, Darcci Freie, Robert Larson

2025 Student Academic Showcase

Blaberus discoidalis, commonly known as discoid cockroaches, are native to South American tropics where they consume leaf litter and decaying organic matter on forest floors. This experiment expands upon previous research concerning the diet preference of discoid cockroaches based on their loitering time when presented with different food types. Utilizing their preferred foods, peanuts, leaf litter, and banana, this experiment aims to determine how much of each food is being consumed to further support their diet preferences.

Gibberlin In Millet Physiology, Torrie Ens, Bella Reaka, Claire Albrecht, Hannah Smallwood, Will Graham, Adam Staley, Garrett Steger, Erin Strong

2025 Student Academic Showcase

Gibberellin is a hormone in plants that affects growth. Gibberellin works to begin germination in grass seeds by stimulating amylase production. It may be possible to use gibberellin to understand why different millet variants exhibit dwarf growth. We grew and treated 4 different dwarf variants with a gibberellic acid solution to identify the ability of each plant to utilize gibberellin. We compared the growth in millet grown both with and without the solution to see the effects of gibberellin on each variant. Dwarf millets may not produce their own gibberellin, or they may lack the receptors to utilize gibberellin. Our …

Analysis Of Differentially Expressed Genes (Degs) Related To Interleukin-17 Signaling For Biomarker Identification And Therapeutic Targets In Atopic Eczema, Siva Fauziah, Weri Veranita, Siti Nurbaya, Puji Sari

Indonesian Journal of Medical Chemistry and Bioinformatics

Atopic eczema, also known as atopic dermatitis, is a chronic inflammatory skin condition characterized by itchy, red, and swollen skin. It is often associated with other atopic diseases such as asthma and hay fever. Interleukin-17 (IL-17), a pro-inflammatory cytokine, plays a crucial role in various inflammatory and autoimmune conditions, including atopic eczema. This study aims to identify potential therapeutic targets for managing atopic eczema based on the analysis of differentially expressed genes (DEGs). The expression of these gene targets was subsequently validated for their potential as biomarkers. Additionally, upstream regulator protein (URP) searches for the resulting DEGs were conducted. DEG …

High-Grade Astrocytoma With Piloid Features: A Single-Institution Case Series And Literature Review, Eric A Goethe, Subhiksha Srinivasan, Swaminathan Kumar, Sujit S Prabhu, Maria A Gubbiotti, Sherise D Ferguson

Faculty, Staff and Student Publications

High-grade astrocytoma with piloid features (HGAP) is a recently described primary brain tumor and the first requiring a specific methylation pattern for diagnosis, as its histologic features are often compatible with other tumors such as glioblastoma (GBM). Characterized by molecular alterations in CDKN2A/B, NF1, BRAF, FGFR1, and ATRX, they may be located anywhere in the CNS but show a predilection for the posterior fossa. Reports are limited to retrospective case series, and the standard of care is not yet established. We performed a retrospective review of electronic medical records of all patients with HGAP at our institution. Records were queried …

Dual Targeting Of Ezh2 And Ezh1 Drives Exit Of Leukemia Stem Cells From Quiescence And Potentiates Chemotherapy In Acute Myeloid Leukemia, Hiroki Akiyama, Yuki Nishida, Kyung Hee Chang, Andrea D Bedoy, Muharrem Muftuoglu, Wencai Ma, Mahesh Basyal, Zoe Hirschi, Daisuke Honma, Shinji Tsutsumi, Jing Wang, Weiguo Zhang, Xuelin Huang, Raajit K Rampal, Olalekan O Oluwole, Dale Lee Bixby, Naval G Daver, Michael Andreeff

Faculty, Staff and Student Publications

No abstract provided.

Meta-Transcriptomes Of The Microbial Communities Of The Different Developmental Life Stages Of Anastrepha Ludens (Diptera: Tephritidae), Erin L. Schuenzel

School of Integrative Biological & Chemical Sciences Faculty Publications

The Mexican fruit fly, Anastrepha ludens, is a polyphagous pest that is a constant threat to US agriculture because of its proximity to citrus production in border region of the United States and Mexico. Sterile Insect Technique has been used to manage and eradicate of the Mexican Fruit Fly. SIT, however, requires millions of sterile male flies to be released each week from mass-rearing facilities. The mass-reared colonies must deal with microbial infections that reduce survivorship, fecundity and male-male competition. Meta-transcriptomics joins culturing and next generation DNA sequencing techniques to understand these changing microbial communities. This study uses advances …

Idh Status Dictates Ohsv Mediated Metabolic Reprogramming Affecting Anti-Tumor Immunity, Upasana Sahu, Matthew P Mullarkey, Sara A Murphy, Joshua C Anderson, Vasanta Putluri, Abu Hena Mostafa Kamal, Jun Hyoung Park, Tae Jin Lee, Alexander L Ling, Benny A Kaipparettu, Ashok Sharma, Nagireddy Putluri, Pamela L Wenzel, Christopher D Willey, E Antonio Chiocca, James M Markert, Balveen Kaur

Faculty, Staff and Student Publications

Identification of isocitrate dehydrogenase (IDH) mutations has uncovered the crucial role of metabolism in gliomagenesis. Oncolytic herpes virus (oHSV) initiates direct tumor debulking by tumor lysis and activates anti-tumor immunity, however, little is known about the role of glioma metabolism in determining oHSV efficacy. Here we identify that oHSV rewires central carbon metabolism increasing glucose utilization towards oxidative phosphorylation and shuttling glutamine towards reductive carboxylation in IDH wildtype glioma. The switch in metabolism results in increased lipid synthesis and cellular ROS. PKC induces ACSL4 in oHSV treated cells leading to lipid peroxidation and ferroptosis. Ferroptosis is critical to launch an …

Survey And Analysis Of Rumen Microbiota In Yaks At Different Growth Stages, Shengwei Jin, Xinyue Liu, Yin-Cang Han, Yong-Gang Sun, Wei-Qin Ding, Ya-Qian Liu, Fa-Jie Gou, Jian-Yu Chen

The Thai Journal of Veterinary Medicine

This study investigated changes in the richness and composition of the rumen microbiome in yaks at various developmental stages. Eighteen healthy male yaks at the ages of 5 months (M5), 12 months (M12), and 24 months (M24) had samples of their rumen digesta taken for 16S rRNA gene sequencing. The 11087 amplicon sequence variations (ASVs) in total were found; the M5, M12, and M24 groups had 3585, 1146 and 5545 distinct ASVs, respectively. Alpha diversity indices Chao, Shannon, Sobs, and ace indicated significant differences among the groups. The principal coordinate analysis (PCoA) indicated significant changes in microbial community composition across …

2025 Acssc Program, Acssc Planning Committee

Annual Celebration for Student Scholarship and Creativity

No abstract provided.

Args & Chronic Disease: How Antibiotic Resistance Genes Impact The Progression Of Type Ii Diabetes, Paige Imperato

Thinking Matters Symposium

Antibiotics are typically offered to patients with no warning of long-term consequences, though increasing evidence suggests this may not be entirely true. When antibiotics enter the body, they kill both good and bad bacterial populations in the gut - collectively known as the human microbiome. Repeated use of these drugs encourages mutations in this bacterial population [2]. This leads to the creation of antibiotic-resistant genes (ARGs) in antibiotic resistant bacteria (ARB). The causal relationship between antibiotic use and bacterial resistance is well established. However, recent research suggests a newly discovered relationship between the presence of specific ARGs in the microbiome …

A Redescription Of Leiurus Libycus (Birula, 1908), Stat. N. (Scorpiones: Buthidae), Ersen A. Yağmur, František Kovařík, Victor Fet

Euscorpius

Buthus quinquestriatus libycus was described by Birula (1908) from the Libyan Desert, based on a subadult male specimen. This taxon was later synonymized with Leiurus quinquestriatus (Ehrenberg, 1828) by Vachon (1949). In this study, we re-evaluate this taxon and recognize it as Leiurus libycus (Birula, 1908), stat. n., providing a redescription based on the holotype. The type locality of this species is clarified as western Egypt (between Alexandria and Fayum). We synonymize Leiurus aegyptiacus Lourenço & El-Hennawy, 2021 with L. libycus, stat. n., syn. n.

Exploring Neural Mechanisms Of Uncertainty Using Eye-Tracking, Olivia Barbarini

Neuroscience Program Student Scholarship

Olivia Barbarini ’26, Neuroscience major

Faculty mentor: Dr. Andra Geana, Neuroscience

The ability to successfully navigate uncertain environments is crucial to human decision-making; this project uses eye-tracking data (gaze and pupil measures) to test how people process perceptual and conceptual uncertainty, and to what extent anxiety influences these processes.

Water Conservation For The Great Salt Lake: Measuring Success And Uncertainty In Utah's Efforts, Sarah E. Witney

Theses and Dissertations

The Great Salt Lake in Utah, United States is one of many saline lakes worldwide that is currently in decline. The shrinkage and collapse of global saline lakes is primarily caused by irrigated agriculture and other human consumptive uses, with secondary contributions from global climate change. Great Salt Lake's area has decreased by more than 50% relative to its long-term natural level. The decline of these lakes triggers serious and long-lasting socioeconomic consequences, including destruction of habitat, degradation of air quality, and damage to the economy. The Utah state government has instituted a variety of programs to conserve water to …

The Significance Of Symmetry: Exploring T-Numbers And Their Role In Virus Survival And Behavior, Jenna Franco, Taylor Ligozio

Mathematics & Computer Science Student Scholarship

Jenna Franco ’25, Biology major

Taylor Ligozio ’25, Biology major

Faculty mentor: Dr. Su Jeong Kang, Mathematics and Computer Science

We studied the symmetry of different structures in common viruses and their T-numbers. We related these T-numbers with characteristics of the virus. Next we researched how the T-number of each virus was optimal for its survival and reproduction in its environment. We can use this information to infer or predict the behavior of viruses in the future based on their T-numbers.

Demography And Habitat Associations Of The Basalt Cactus Pediocactus Nigrispinus, Zarha S. Dillon-Zuppelli, Mary E. Poulson, Eric A. Graham

Biology Faculty Scholarship

Cacti are iconic members of arid ecosystems. Pediocactus nigrispinus is a species of cactus endemic to the Pacific Northwest and has been listed as a sensitive species due to its vulnerability to habitat loss. Best conservation methods for this species are poorly understood, due in part to a limited understanding of its demography and habitat associations that may help define its occurrence. A demographic study from four plots in Washington State was implemented in 2016 to provide a baseline of the population dynamics for P. nigrispinus and to enhance conservation efforts for this sensitive species. Five years of size, fecundity, …

Food & Drugs Unite: Targeting Leukemia With A [6]-Gingerol And 5-Fluorouracil Combination Chemotherapy, Alexa Mazzeo, Samantha Wechsler

Biology Presentations

Leukemia is a cancer found in the blood characterized by rapid growth of blood cells. This study examines the effect of [6]-Gingerol and 5- Fluorouracil (5-FU) on the proliferation of the Jurkat cell line, a cell line that is a model for T-cell leukemia due to similar mechanisms. MTT assay technique was used to measure cell proliferation and viability. We expected to see high cell fractional affect and reduced proliferation as the concentrations of the combinational therapy of [6]-Gingerol and 5-FU increased. These two cell compounds were selected because of their anti-carcinogenic effects: [6]-Gingerol is used aid in the inflammation …

Development And Validation Of A Dynamic Real-Time Risk Prediction Model For Intensive Care Units Patients Based On Longitudinal Irregular Data: Multicenter Retrospective Study, Zhuo Zheng, Jiawei Luo, Yingchao Zhu, Lei Du, Lan Lan, Xiaobo Zhou, Xiaoyan Yang, Shixin Huang

Faculty, Staff and Student Publications

Background: Timely and accurate prediction of short-term mortality is critical in intensive care units (ICUs), where patients' conditions change rapidly. Traditional scoring systems, such as the Simplified Acute Physiology Score and Acute Physiology and Chronic Health Evaluation, rely on static variables collected within the first 24 hours of admission and do not account for continuously evolving clinical states. These systems lack real-time adaptability, interpretability, and generalizability. With the increasing availability of high-frequency electronic medical record (EMR) data, machine learning (ML) approaches have emerged as powerful tools to model complex temporal patterns and support dynamic clinical decision-making. However, existing models are …

Exploring The Role Of Azoreductase Enzymes In Drug Metabolism: Implications For Personalized Medicine, Najoude Claude, Robert Ghergurovich

Chemistry & Biochemistry Student Scholarship

Najoude Claude ’26, Biology major

Robert Ghergurovich ’26, Biochemistry major

Faculty mentor: Dr. Tyler Stack, Chemistry and Biochemistry

The gut microbiome hosts trillions of microorganisms that metabolize xenobiotics such as drugs and food dyes. Individual differences lead to variable drug metabolism. We studied two azoreductases: E. coli’s P41407 and Alistipes sp. CHKCL003’s A0A143XFE8. Enzyme P41407 acted on methyl red and ethyl red, while A0A143XFE8 acted on these and also on phenol blue, HMND, and sunset yellow. We propose these enzymes function as quinone reductases, requiring a quinone-like intermediate. Three synthesized compounds confirmed similar kinetics. In conclusion, these insights significantly advance …

Shelving Stigma: A Grocery Store Client Choice Pantry Model - A Solution To Food Insecurity In Young Adults Of Marginalized Communities While Eradicating The Stigmatization Of Food Pantry Services, Anna C. Buckley

Honors Theses

An increasing number of young adults, age 18 to 35, are becoming food insecure across America, but disproportionately in urban and people of color communities. However, food pantries have remained a social stigma causing food insecure persons to avoid using a food pantry for hunger relief. Research has shown that the grocery store model for food pantries is most beneficial for staff, while also minimizing the stigma and increasing accessibility for pantry clientele. The purpose of this program proposal is to highlight the feasibility of implementation of a client choice grocery store pantry model at the NY Common Pantry (NYCP) …

Efficiency’S Role In Irrigation And Nitrogen Use, Matt Stockton, Shannon Sand

Cornhusker Economics

Summary

The WNIPI is a purely physical measure of I and N efficiency and was developed to determine efficiency winners in several TAPS contests. DRIN is a powerful tool in measuring the effectiveness of the dollars spent on I and N. It is a ratio of dollars returned as revenue in terms of dollars spent. The third measure, NRIN, is an overall measure of economic gain. It is the difference in money spent on I and N versus the revenue taken in and measures the volume of net returns. Both DRIN and the NRIN measure dollar effectiveness dependent on the …

Development Of Edna Tools For Biomonitoring, Stella Grondin, Anthony Aldana – Mendez

Biology Student Scholarship

Stella Grondin ’27, Biology major

Anthony Aldana – Mendez ’27, Biology and Psychology major

Faculty mentor: Dr. Jeffrey Markert, Biology

Effects Of Integrated Pest Management On Honey Bee Behavior And Colony Level Health, Kaitlyn Bresnahan

Biology Student Scholarship

Kaitlyn Bresnahan ’25, Biology major

Faculty mentor: Dr. Rachael Bonoan, Biology

Honey bees face threats from many directions, but the most pressing is the parasitic mite Varroa destructor. One popular method of combatting Varroa is adding drone comb which forces the colony to raise larger, mite-preferred male bees. While this method reduces mite numbers, it may add unnecessary colony-level stress. My research investigates how forcing the hive to raise drones for mite management affects honey bee population growth and foraging behavior. This was accomplished by estimating adult bee population and area of drone brood, and by examining foraging behavior of …

Quantifying The Relationship Between Biomass And Edna​, Andrew K. Hogan

Biology Student Scholarship

Andrew K. Hogan ’27, Environmental Biology and English Literature major

Faculty mentor: Dr. Jeffrey Markert, Biology

In this project, we compared eDNA concentration in water to the biomass of present creatures and the time the eDNA in each sample took to decay. With this data, standard curves for both variables can be created and can be used for future experiments and field research. This data will give researchers a greater level of understanding about what animal populations might look like based on the eDNA obtained.

Effects Of Hyperglycemia In Cognition And Sex, Erin E. Mcdonald

Senior Honors Theses

An empirical study tested the effects of Type 1 Diabetes (T1D) on cognitive function in a hyperglycemic mouse model. Strong correlations between mental illnesses, such as major depressive disorder, neuropathologies like Alzheimer’s disease, and diabetes suggest comorbid pathology. Considering the prevalence of both T1D and cognitive decline within the general population, the findings were relevant and aimed to identify early signs of cognitive decline in diabetic patients. Behavioral tests and immunohistochemical staining were utilized to determine the cognitive function of the mice, revealing decline or deterioration caused by hyperglycemia. Data gathered from the hyperglycemic or control mice were analyzed based …