Life Sciences Commons^™

Screening Of A Diversity Of Legumes And Non-Legumes Forb Species At Five Strategic Locations Across Utah For The Development Of Smart Foodscapes, Surbhi Verma

All Graduate Theses and Dissertations, Fall 2023 to Present

Grass-dominated rangelands in the Western United States often lack sufficient protein for pregnant cows after grasses mature in mid- summer, leading ranchers to rely on expensive feed supplements such as protein cubes or alfalfa hay. The goal of this study was to screen 27 perennial legume and forb species with the potential to remain green into late summer and provide sufficient protein to supplement cows on grass-dominated rangeland. Three experiments were carried out to understand germination of species, plant establishment and persistence at five Utah locations, and agronomic characteristics. The seed of five hard-to-germinate species were studied for the ability …

Gone With The Flow: Flow Reduction Coincides With Reduced Metabolism And Standing Stock Of Benthic Algae And Macroinvertebrates In Desert Rivers, Chloe E. Lyles

All Graduate Theses and Dissertations, Fall 2023 to Present

River metabolism, the measure of energy flow in a river, is driven by hydrological and physicochemical regimes (e.g., temperature, turbidity, and nutrients). However, these regimes are increasingly altered by human water demand and climate change-driven drought. These stressors alter the magnitude, timing, and duration of critical spring-snowmelt floods with poorly understood consequences on ecosystem function, particularly in desert rivers. To investigate the linkages between flow reduction, river metabolism, and basal food resource productivity (i.e., algae and aquatic invertebrates), we measured metabolism and basal resource availability in seven desert tributaries with varying degrees of flow reduction during low-flow conditions in 2023 …

Understanding The Impact Of Colloidal Calcium Phosphate On The Ph Variation In Cheddar Cheese During Early Stages Of Aging, Rachel Lindstrom

All Graduate Theses and Dissertations, Fall 2023 to Present

The Cheddar cheese industry has recently observed variation in the pH of their cheese during the early stage of storage. This variation may be due to the addition of the faster acid producing thermophilic starter culture Streptococcus thermophilus which was recently introduced into the Cheddar cheese making process. This starter culture may impact the calcium buffering properties of the cheese due to more retention of the insoluble calcium (INSOL Ca) within the cheese. To investigate this problem, we studied how insoluble calcium affects cheeses with pH ranging from 4.8 to 6.6 and found that INSOL Ca was positively correlated with …

Maximizing Dryland Seed-Based Restoration Success Via Retrospective Analyses Of Species-Use Patterns And Field Testing Of Seed Mix Composition, Spencer J. Good

All Graduate Theses and Dissertations, Fall 2023 to Present

Due to harsh and variable environmental conditions, successful plant establishment in "dryland" ecosystems – areas with scarce precipitation – is a major challenge for restoration. One of the most important decisions influencing restoration outcomes is choosing which species to plant (i.e., species selection). Here I explored two opportunities to improve restoration success related to species selection. First, I examined recent restoration projects across Utah, USA to understand species selection patterns by site conditions (e.g., precipitation, elevation) and seed costs, and to identify tools for matching species to sites. Second, I tested how commonly used non-native species – those not originally …

First Specimen-Based Record Of Barbonymus Schwanefeldii (Bleeker, 1854) (Teleostei: Cyprinidae) From Laguna De Bay, Philippines, Kent Elson S. Sorgon, Marjorie Juliana L. Martinez, Andrei Justin F. So, Mariko Franccesca R. Aboganda, Jazreen Nicole G. Parungo, Aeris Johanne G. Poricallan, Keona Tiffany B. Prieto, Mellissa Jewel S. Magday, Alexa Charlize Dc Geronimo, Ma. Vianca Julia E. Anupol, Derreck O. De Leon

Biology Faculty Publications

The introduction of non-native fish species in the freshwater ecosystems of the Philippines presents a clear threat to native ichthyofauna, making verified reports of such introductions all the more critical. Through the examination of a collected specimen and anecdotes from fisherfolk and social media, we present here the first records of the occurrence of the tinfoil barb, Barbonymus schwanefeldii (Bleeker, 1854), in Laguna de Bay, Luzon Island, Philippines. This represents the addition of another non-native fish species in this lake, which is increasingly becoming dominated by non-native and invasive fishes that have been intentionally or accidentally introduced. Monitoring landed fish …

Volatile Organic Compounds And Their Relation To Sympathetic Activation And Autonomic Balance In Humans., Cameron Kyle Stopforth

Electronic Theses and Dissertations

Cardiovascular disease (CVD) is a multifaceted pathology that affects almost half of Americans ≥20 years old. One modifiable risk factor associated with CVD is air pollution exposure. The intricacy of air pollution exposure and CVD can make it difficult to elucidate on the multitude of mechanisms underpinning these associations. In this dissertation, we selected a relevant exposure (i.e., volatile organic compounds (VOC)) and an intermediate outcome (i.e., autonomic balance) that may represent one of these pertinent mechanisms. We tested the central hypothesis that higher VOC exposures would lead to increased sympathetic activation and autonomic imbalance. Aim 1 (Chapter III …

Wildfires Impact On Water Treatment, Alli Willmarth, Matthew Jorgenson, Kyle Shimabuku

CURCI Student Research

Study Objective: Determine the effectiveness of using powder activated carbon to remove wildfire dissolved organic matter (DOM).

Effects Of Novel Dopamine D4 Receptor-Targeted Compounds On Locomotor Activity And Anxiety-Like Behavior In Male And Female Sprague Dawley Rats, Samantha Alyse Walkow, Noah A. Ivak, Daniel Chandler, John Tkaczynski, Thomas M. Keck, Comfort A. Boateng, Eleni Papadopoulos, Barry D. Waterhouse, Rachel L. Navarra

Rowan-Virtua Research Day

The consequences of modulating subtypes of G protein coupled dopamine receptors are broadly studied for their role in decision making behavior, specifically in situations involving uncertain risk and reward. The actions of dopamine D4 receptors (D4Rs) on these complex processes are the least understood, particularly due to a lack of available compounds with suitable selectivity for D4Rs. Further, current research often fails to evaluate how modulating specific dopamine receptor subtypes may affect locomotor activity and anxiety-like behavior as confounding factors prior to assessing their function in behavioral assays of higher order decision making. The goal of the current study was …

Ks151 Synergizes With Venetoclax And Abt-737 In Aml: Efficacy In Both Flt3-Wildtype And Flt3-Mutant Models, Sahil Jethi, Arnold Rojas, Omar S. Al-Odat, Krishne Gowda, Subash C. Jonnalagadda, Manoj Pandey

Rowan-Virtua Research Day

Acute myeloid leukemia (AML) is the most common leukemia in adult patients, with a 5-year survival rate of less than 30 percent. Therefore, more effective therapeutic strategies are required to prolong the survival of AML patients. Importantly, anti-apoptotic proteins, especially B-cell lymphoma 2 (Bcl-2), overexpression in AML is associated with uncontrolled growth as well as chemoresistance. Unsurprisingly, Bruton’s tyrosine kinase (BTK) overexpresses in AML and associated with poor prognosis and chemoresistance. The FDA-approved BTK inhibitor, ibrutinib, has been successful in treating other hematologic malignancies, but a proportion of patients relapse mainly because of acquired mutations at Cys481Ser (C481S) in the …

Characterizing Environmental Background Microflora And Assessing Their Influence On Listeria Persistence In Dairy Processing Environment, Vaishali Poswal, Sanjeev Anand, Brian Kraus

Dairy Science and Food Science Faculty Publications: 2022 to Present

Listeria monocytogenes (Lm) may persist in food processing environments (FPEs) alongside diverse background microflora. While microbial communities in FPEs can in- fluence Lm survival, their role in supporting or suppressing its growth remains unclear. This study aimed to characterize the microflora in floor swabs and air samples collected from a dairy processing facility across three seasons and assess their potential impact on the growth of a Lm test strain previously isolated from a dairy processing environment. A total of 167 environmental isolates, representing 30 bacterial genera, were identified. Pseudomonas was consistently prevalent across all sample types. Seasonal shifts in bacterial …

Investigating Fatty Acid Influence On West Nile Virus In Mosquitoes And Birds, Hayley Moree

Honors Program: Senior Projects (Public)

Vector-borne diseases, including Zika virus (ZIKV), Dengue virus (DENV), and West Nile virus (WNV), pose considerable global health threats, accounting for over 400 million infections and more than 700,000 deaths annually. Many vector-borne diseases are within the Flaviviridae family. Despite this, effective treatments have not been found for some flaviviruses. Flaviviruses exploit host cellular machinery to facilitate their replication and survival, reprogramming metabolic pathways, including lipid metabolism. Lipids play essential roles in the viral life cycle, providing structural components for the viral envelope, enabling membrane rearrangements for replication complexes, and supplying energy resources necessary for particle assembly.

Targeting lipid metabolism …

Novel Chloroviruses With Unique Glycans On Their Major Capsid Proteins, Cayden J. Homolka

Honors Program: Senior Projects (Public)

Chloroviruses, of the family Phycodnaviridae, are large, dsDNA viruses with a genome of 290 to 410 kb. These virus genomes are so large that they are classified as “giant viruses”. Within this genome, up to 16 tRNAs and 330 to 450 proteins are encoded. Among the massive amounts of genes and proteins are unique carbohydrate synthesis/metabolism genes, which are responsible for the glycosylation of chloroviruses major capsid proteins. In most viruses, these proteins are glycosylated by the host enzymes located in the endoplasmic reticulum. Instead, Chloroviruses encode their own glycosylation machinery; essentially decorating themselves. Furthermore, these chlorovirus glycans are unlike …

The Perceived Effect Of The Menstrual Cycle On Sleep, Mood, And Training In Ncaa Di Collegiate Athletes, Rachel Conhoff

All-Inclusive List of Electronic Theses and Dissertations

Purpose: This study aimed to understand whether collegiate female athletes perceived that their menstrual cycle influenced sleep, mood, and training. Additionally, it looked to identify which phases of the menstrual cycle (pre-menstruation, menstruation, and post-menstruation) were associated with a positive perception of these three variables. Methods: An online questionnaire was designed and sent out to all NCAA Division I (DI) female athletes whose schools had permitted them to participate in the study. The questionnaire was a novel instrument that assessed the perception of the menstrual cycle on the three variables across the three phases. Inclusion criteria included NCAA DI female …

Effects Of Intradermal Injections Of Lipopolysaccharide On The Local And Systemic Acute Inflammatory Responses In Turkeys, Delaney F. Roberts

Poultry Science Undergraduate Honors Theses

In chickens, the growing feather (GF) pulp has been established as a cutaneous bioassay to monitor and assess tissue/cellular immune activities in response to intradermal (i.d.) injections of test materials. The objective of this pilot study was to determine the suitability of the GF bioassay in turkeys by examining the acute inflammatory responses initiated by i.d. GF-pulp injections of lipopolysaccharide (LPS). For this, three, 5-wk-old turkey poults were used. Two poults had 8 GFs injected (10 μL/GF) with low (L)-LPS (0.1 μg/GF) and 8 GFs with high (H)-LPS (1 μg/GF), while a third poult had 8 GFs injected with endotoxin-free …

Quantifying Freshwater Salinization Impacts On Nitrate Removal Via Denitrification In Urban Streams, Brynnen Beck

Crop, Soil and Environmental Sciences Undergraduate Honors Theses

As the urban world expands, the construction of impervious surfaces increases erosion and runoff into nearby streams. Urbanization also adds waste from human activity into the environment. One of these wastes is runoff from road salt application in winter months, which can increase stream salinization and interfere with other important ecological processes, such as denitrification. Therefore, the objective of this study was to compare nitrate removal via denitrification between two urban streams to understand the role of road salts in freshwater salinization. We compared conductivity measurements between the streams to see how background conductivity (a proxy for salinity) influences resilience …

The Movement Ecology, Ranging Patterns, And Territoriality Of Azara’S Owl Monkeys (Aotus Azarae) In The Argentinean Chaco Forest, Jeremy D. Pustilnik

Master of Environmental Science Theses

Azara’s owl monkeys (Aotus azarae) are small, pair-living, socially monogamous primates that inhabit the Chaco Forest of South America. Their activity and life history patterns have been particularly well studied, however, their movement ecology and ranging patterns within their home ranges remains largely unknown. Herein I descriptively analyze these patterns with respect to time, space, ambient environment, and physical environment using spatial information on five owl monkey groups that were followed over the course of a year between 1998 and 1999 at a multi-decade-operating field site near Formosa, Argentina. Analysis of distance and speed moved during different diel …

The Great Animal Rights Debate: From The Past Into The Present, Dayna Wiley

Celebrating Scholarship and Creativity Day (2018-)

Animal rights are not a novel concept, and everyone has their own beliefs about where animals should fit into the hierarchy of life. Not so different from today, a debate occurred in the ancient world between the Stoics, represented by Aristotle, and Plutarch, with each questioning whether animals are capable of rational thought or feelings, and therefore whether they are deserving of justice. There is much to learn from the ancient world about the modern debate on animal rights, and there is a striking comparison between this ancient debate and the modern questions of animal rights. But how similar are …

Multi-Domain Machine Learning For Biological Classification: Mallard Classification And Protein Function Prediction, Tolulope Samuel Adeyina

Open Access Theses & Dissertations

Multi-domain machine learning applications have revolutionized how we understand and predict complex biological phenomena. This dissertation presents novel computational methodologies addressing two critical problems: mallard classification using single-nucleotide polymorphisms (SNPs), and protein function prediction via interpretable topic-aware peptide embeddings. The research focuses on distinguishing mallard populations through SNP data, which are inherently characterized by ultra-high dimensionality. The research uses advanced feature-selection and dimensionality-reduction strategies alongside machine learning classification algorithms to identify minimal, yet highly predictive SNP sets crucial for accurate breed differentiation. This framework demonstrates robust performance with optimal computational efficiency, significantly aiding conservation and breed management efforts. Furthermore, the …

Sustainable Agriculture Through Data-Driven Land And Soil Management For Rural Farming Communities, Peggy Clareece Discenza

Open Access Theses & Dissertations

This thesis aims to investigate sustainable farming practices by utilizing a database containing soil, weather, and water data. Additionally, it evaluates cropping strategies using a system that incorporates nutrient dynamics and environmental values. The objective is to monitor, develop predictive models, and assess the impact of both controlled and uncontrolled nutrient variables. This is achieved through the development of an algorithm that provides information on soil health based on datasets and land use, with a particular focus on residual values after harvesting for deeper analytical insights and interpretation. This study focuses on key nutrients, including pH levels, water availability, and …

Pathways Of Nitrogen Loss After Fertilization In Dryland Ecosystems, Fidel Manuel Renteria

Open Access Theses & Dissertations

Dryland ecosystems cover approximately 41% of the Earth’s terrestrial surface, and are characterized by limited moisture, nutrient-poor soils, and pulsed precipitation regimes that collectively constrain nutrient cycling. Although nitrogen (N) is often assumed to be a primary limiting nutrient in these environments, fertilization studies frequently reveal minimal biotic response to added N—a pattern known as the "dryland nitrogen paradox." This paradox has been attributed to rapid nitrogen loss via gaseous emissions and leaching, exacerbated by interactions with water and phosphorus (P) availability. To investigate these loss pathways, we conducted a field experiment at the Jornada Experimental Range in the northern …

Navigating The Challenges Of Coccidioides Surveillance: Insights From The Environment Of El Paso County, Texas, Tanzir Hossain

Open Access Theses & Dissertations

Coccidioidomycosis, or Valley fever, is a fungal infection resulting from the inhalation of spores from the Coccidioides species (C. immitis and C. posadasii), native to arid areas of the Western Hemisphere. Coccidioidomycosis presents considerable health hazards and can be fatal. It affects between 206,000 and 360,000 individuals annually, leading to 700 to 1,100 fatalities in the United States alone. In response to these issues, extensive research has concentrated on therapeutic goals for this infectious disease. Nonetheless, more limited research has focused on the environmental detection of its causative fungi, which is crucial for forecasting treatment needs and formulating preventive strategies. …

Assessing The Implicit Prices Of Health And Wellness Product Attributes In Pet Food: A Hedonic Analysis Approach, Lonnie Hobbs Jr., Andrew Anderson

Agricultural Economics and Agribusiness Faculty Publications and Presentations

Here we examine product attributes present in dry dog food to show there exist potential price premiums and discounts associated with health and wellness attributes in dry dog food. The findings indicate price premiums are associated with attributes related to digestion and allergy care. Pricing discounts are found to be associated with immune support and dental attributes. The results of this study are anticipated to be a starting point for more sophisticated and dynamic analysis of pricing and willingness-to-pay studies in the pet food industry.

Investigation Into Mycorrhizae Associated With Native Venus' Flytrap Root Tissue, Anna Carnaggio

Electronic Theses and Dissertations

Dionaea muscipula, a plant commonly known as the Venus' flytrap, is found native to the southeast corner of North Carolina and the northeast corner of South Carolina. Several populations of native Venus' flytraps are known to exist in the nutrient-poor peat bog conditions in and around Lewis Ocean Bay Heritage Preserve (LOBHP) in Northeastern South Carolina. Anthropogenic pressures in Horry County, specifically surrounding LOBHP, have resulted in a loss of habitat for several native and endangered species. As a result, conservation efforts are focused on relocating native Venus' flytraps into adjacent habitats to ensure survival. This is only a temporary …

Understanding The Impact Of Fall Armyworm (Spodoptera Frugiperda) Feeding, And Drought Stress On Drought-Tolerant And Drought-Resistant Soybean (Glycine Max)., Adriana G. Peissel

Crop, Soil and Environmental Sciences Undergraduate Honors Theses

Drought and insect herbivory are two major stressors on high-value crops like soybean (Glycine max). However, few studies have explored how these stressors interact, despite their presence in tandem under field conditions. We investigated how drought stress and fall armyworm (Spodoptera frugiperda) caterpillar herbivory impact Magellan (drought-tolerant) and Blackhawk (drought-susceptible) soybean cultivars. The soybean plants were subject to four treatment groups (1. Drought 2. Herbivory 3. Drought + Herbivory 4. Well-Watered) during a treatment period of 7 days in a greenhouse. We then measured plant height, physiological traits, trichome density, soil moisture, and larval mass gain. …

Understanding Factors That Drive Wildlife Mortality During Prescribed Fire Management Of Prairie Restorations, Hunter M. Griffey

Crop, Soil and Environmental Sciences Undergraduate Honors Theses

Fire is a key ecological disturbance, which plays a vital role in maintaining biodiversity and early successional species. For today’s land managers, prescribed fire is key in the restoration and maintenance of prairie ecosystems, halting woody encroachment and creating habitat desperately needed by many species. However, fire may have unintended effects on wildlife populations through direct mortality. Among taxa living in fire-dependent ecosystems, reptiles are predisposed to direct mortality, and several studies have recorded significant mortality during prescribed burns. However, the few studies investigating reptile mortality in prescribed fire are limited by small sample sizes and generally have limited analysis …

Toward The Application Of Natural Language Processing In Electronic Health Record Analysis For Taxonomy Development, Latoya Mcdonald

All Dissertations

Electronic health records (EHRs) are pivotal resources for nurse practice because they increase the timeliness and reliability of patient information at the point of care and support access by multiple healthcare providers and the individual patients themselves. However, it is widely recognized that data extraction from EHRs is challenging due to the variability in the language used in clinical care notes and the lack of standardized terminology across healthcare systems. The broad objective of this dissertation is to develop taxonomy-based classification models for nursing care by applying feature engineering approaches to EHRs that include nursing care of ostomy patients following …

Development Of Small-Molecule Inhibitors For Bacteroides, Naegleria, And Toxoplasma Microorganisms And Synthesis Of N-Heterocycles From Thiolated Ene-Ynes And Azodicarboxylates, Samuel Kwain

All Dissertations

Humans and microorganisms are intricately interconnected, with microbes constituting an essential component of human biology and ecology. This interdependence necessitates a delicate balance between leveraging beneficial microbes and mitigating the impact of harmful ones. The human gut microbiome, home to trillions of microorganisms, predominantly comprises commensal species that support health. However, dysbiosis within this ecosystem has been linked to serious diseases. For instance, an overrepresentation of Bacteroides species is associated with Type I diabetes mellitus (T1D) and various chronic gut disorders, including ulcerative colitis, inflammatory bowel disease, celiac disease, and colorectal cancer. Similarly, Naegleria fowleri, a free-living amoeba, causes …

Perspectives On Clinical Oncogenomics: Secondary Germline Variants Associated With Tumor Genomic Profiling In Community Cancer Care And Advanced Practitioner Oncogenomic Proficiency, Sarah Moncado

All Dissertations

Precision medicine in oncology is defined by the sequencing of tumor genomic variants that can be used to identify targeted treatment for patients. Secondary pathogenic and likely pathogenic germline variants (P/LPGVs) can incidentally be detected on tumor genomic profiling (TGP). With the rise in precision medicine over the past 15 years, secondary P/LPGVs on TGP have been an increasingly important clinical issue. However, there are factors that can lead to misidentification and underreporting of P/LPGVs. Germane to this clinical practice issue is healthcare provider oncogenomic literacy and proficiency.

A scoping review was conducted to evaluate the variability of the prevalence …

A System And Method For Measuring Spatially Varying Surface Appearances With A Study Of Feathers, Jessica Baron-Lis

All Dissertations

Real-world materials, particularly biological structures such as feathers exhibit complex appearances that vary spatially across their surfaces. The field of computer graphics provides a means of understanding such surfaces through material modeling which uses both analytical models and data acquired from light-surface interactions. There are many efforts within the past decade in measuring materials for graphics, but common limitations in these works include not accounting for spatially varying properties and reliance on neural networks and synthetic datasets.

Feathers from modern birds present diverse appearances due to how light interacts with their unique hierarchical microstructures. Variations in those structures lead to …

Investigate The Use Of Nucleic Acids As Pesticides To Manage Major Pests And Pathogens Of Crops In South Carolina, Prasanna Valavanur Shekar

All Dissertations

The sugarcane aphid (SCA, Melanaphis sorghi), first discovered on grain sorghum in late 2013, has gradually become a major insect pest of sorghum. It inflicts significant damage to the crop year after year, causing millions of dollars in losses throughout the sorghum-producing regions of the United States. Similarly, Armillaria root rot—also referred to as oak root rot—is a major cause of decline in peach (Prunus persica) production in the southeastern United States. This disease is caused by Armillaria mellea and Armillaria tabescens. Current management practices for controlling M. sorghi include the use of synthetic pesticides, resistant varieties, and regular scouting. …