Life Sciences Commons^™

Are Electronic Cigarettes The Solution To Smoking Cessation?, Heather L. Walsh, Audrey L. Mcmurray

Physician Assistant Capstones, 2016 to 2019

Objectives: Little is known regarding the effectiveness of electronic cigarettes (e-cigarettes) as therapy to aid in smoking cessation. Many hypothesize that e-cigarettes are equally as effective or more effective than alternate smoking cessation therapies. The purpose of this review was to examine the evidence on effectiveness of e-cigarettes on smoking cessation and quitting behavior as compared to other smoking cessation therapies, or no therapy at all.

Methods: Searches were done in PubMed utilizing the terms “electronic cigarettes” and “smoking cessation” [MeSH terms]. In PubMed, the following filters limits were used: published in the last 5 years, human species, …

Corral De Tierra (Mccobb) - Diseños, Glo No. 290, Monterey County, And Associated Historical Documents.

Individual Ranchos in Monterey and SLO Counties

Diseños - Hand-drawn Spanish-Mexican map demonstrating the physical boundaries of land granted to Mexican citizens by the Spanish or Mexican.

Expediente – Hand-written Spanish-Mexican land grant document issued to Mexican citizens in Alta California for land in Alta-California.

Work Progress Administration Abstract (WPA Abstract) – A summary document prepared in 1938 under the Work Progress Administration program detailing the history of a rancho beginning with the Spanish-American land through the U.S. patenting process.

Hoffman Notes -- Summary of information concerning claims made for the Rancho lands from the Appendix listing Table of Land Claims in the Reports of Land Cases …

A 16-Week Run Sprint Interval Training Does Not Have An Effect On Cardiovascular Risk Measured By Framingham Risk Score On Prediabetic Women, Joan A. Mandelson

Masters Theses, 2010-2019

The Framingham risk score (FRS) was developed to determine the likelihood of developing cardiovascular disease (CVD) in the next 10 years using an individual’s age, gender, total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), smoking habits, and systolic blood pressure (SBP). Run-sprint interval training (R-SIT) has shown improvements in various health and blood markers while reducing total exercise time. To date there has not been a study that examines the effects of R-SIT and moderate intensity training (MIT) on framingham risk. The purpose of this study was to determine if a reduction of the 10-year risk of CVD (determined by …

A Low-Carbohydrate Ketogenic Diet Combined With Six Weeks Of Crossfit Training Improves Body Composition And Performance, Rachel M. Gregory

Masters Theses, 2010-2019

A low-carbohydrate ketogenic diet (LCKD) is a popular approach to weight and fat loss. CrossFit is a high-intensity power training (HIPT) type exercise for all levels of age and fitness that has gained recognition as one of the fasting growing sports in America. No previous research has been found which examines body composition changes or performance in individuals consuming a LCKD and participating in CrossFit training. PURPOSE: The purpose of this research was to examine the effects of a 6-week LCKD and CrossFit program on body composition and performance. METHODS: Twenty-seven non-elite CrossFit subjects (mean ± SD age = …

The Effect Of Sleep Restriction On Coagulation And Fibrinolysis After Heavy Exercise, Paul A. Roberson

Masters Theses, 2010-2019

Introduction: Research has shown exercise elicits a hemostatic response affecting coagulation and fibrinolysis. Furthermore, prior research has determined circadian fluctuations exist where clotting potential increases in the morning as a result of increased PAI-1 and decreased tPA which is further exacerbated by exercise. These circadian fluctuations and exercise responses have the potential to be accentuated by poor sleep. The purpose of this study is to determine the effects of sleep restriction on tPA activity, PAI-1 activity, and Factor VIII antigen activity (FVIII) while resting and after exercise.

Methods: 7 Subjects underwent two similar exercises sessions (EX). EX1 occurred in the …

The Influence Of Time-Of-Day Consumption And Training Status On The Ergogenic Properties Of Caffeine, James C. Boyett

Masters Theses, 2010-2019

Purpose: The objectives were to determine the effects of time-of-day consumption and training status on the benefits of caffeine supplementation for cycling performance and peak muscle strength. METHODS: Twenty untrained and trained subjects completed four trials consisting of isokinetic peak torque testing and 3-km time trials (TT). Subjects ingested either 6 mg/kg of caffeine or a placebo one hour prior to each trial. Treatments were: morning + placebo, morning + caffeine, evening + placebo, evening + caffeine. Magnitude based inferences were used to evaluate treatment differences. RESULTS: Caffeine (‘very likely’ and ‘likely’) improved 3-km TT performance in the morning and …

The Effect Of Water Quality On The Survival And Fitness Of Brook Trout (Salvelinus Fontinalis) Eggs, Alevins And Fry In Aquaculture And Deep Springs Along The South River In Waynesboro, Va, Thomas D. Teears

Masters Theses, 2010-2019

Brook trout populations have been extirpated in many Virginia streams due to poor water quality thus establishing populations of brook trout for recreational fishing is an important priority of fisheries management. The ability of a stream to protect developing brook trout (Salvelinus fontinalis) eggs and larval fish from adverse effects from acidification and metal toxicity as well as provide needed minerals such as magnesium (Mg²⁺) and calcium (Ca²⁺) for early-stage development is controlled primarily by geology, which influences water hardness and acid-neutralizing capacity (ANC). The focus of this research was on the effects of …

Using Morphometrics To Evaluate Taxonomic Relationships In Eleocharis Tenuis (Cyperaceae), Lane D. Gibbons

Masters Theses, 2010-2019

North America is host to multiple complex taxa, and unresolved relationships in the genus Eleocharis (Cyperaceae). Of noteworthy significance, are lasting taxonomic uncertainties involving plants referable to E. tenuis (var. tenuis, var. verrucosa, and var. pseudoptera) of the E. tenuis species complex. Morphology of E. tenuis is traditionally recognized as being widely variable, and intermediate among taxa along a broad geographic gradient. Cytological and morphometric data however, indicate that the varieties of E. tenuis are unique in cytology, and are consistently delimited by five morphological characters. Furthermore, this study shows that cytological data correlates with unique morphological …

A Mutation In Ltbp2 Causes Congenital Glaucoma In Domestic Cats (Felis Catus), Markus H. Kuehn, Koren A. Lipsett, Marilyn Menotti-Raymond, S. Scott Whitmore, Todd E. Scheetz, Victor A. David, Stephen J. O'Brien, Zhongyuan Zhao, Jackie K. Jens, Elizabeth M. Snella, N. Matthew Ellinwood, Gillian J. Mclellan

Chemistry Faculty Publications

The glaucomas are a group of diseases characterized by optic nerve damage that together represent a leading cause of blindness in the human population and in domestic animals. Here we report a mutation in LTBP2 that causes primary congenital glaucoma (PCG) in domestic cats. We identified a spontaneous form of PCG in cats and established a breeding colony segregating for PCG consistent with fully penetrant, autosomal recessive inheritance of the trait. Elevated intraocular pressure, globe enlargement and elongated ciliary processes were consistently observed in all affected cats by 8 weeks of age. Varying degrees of optic nerve damage resulted by …

A Single Night Of Sleep Restriction Impairs Recovery From Heavy Exercise, John D. Chase

Masters Theses, 2010-2019

We examined the effects of one night of sleep restriction (Sleep-; 2.5 hrs) on subsequent 3-km cycling performance and skeletal muscle recovery from heavy exercise compared to a full night of rest (Sleep+; 7 hrs). Seven recreational cyclists (n=6 male, n=1 female; age = 24.4 ± 7 yrs; height = 170 ± 10 cm; weight = 68 ± 13 kg VO_2max = 61.5 ± 4.4 ml/kg/min) completed four simulated 3-km time trials (TT) and six peak isokinetic torque trials at different speeds (30 and 120°/sec) under both conditions. The first exercise trial (EX1) consisted …

Next-Generation Sequencing Of A Multi-Drug Resistance Plasmid Captured From Stream Sediment, Kevin G. Libuit

Masters Theses, 2010-2019

Plasmids in agriculturally-impacted bodies of water may play a significant role in the dissemination of antibiotic resistance. Previously, Erika Gehr, as part of her M.S. thesis work in our laboratory, captured environmental plasmids without cultivation of host bacteria from stream sediment into Escherichia coli. Individual plasmids were capable of conferring resistance to a surprising array of antibiotics including aminoglycosides and extended-spectrum β-lactams. In this study, we developed a method to sequence multi-drug resistance plasmids using both Oxford Nanopore MinION and Ion Torrent Personal Genome Machine sequencers. Plasmid pEG1-1 was sequenced on both platforms and a hybrid assembly utilizing data …

Chualar - Diseños, Glo No. 270, Monterey County, And Associated Historical Documents.

Individual Ranchos in Monterey and SLO Counties

Diseños - Hand-drawn Spanish-Mexican map demonstrating the physical boundaries of land granted to Mexican citizens by the Spanish or Mexican.

Expediente – Hand-written Spanish-Mexican land grant document issued to Mexican citizens in Alta California for land in Alta-California.

Work Progress Administration Abstract (WPA Abstract) – A summary document prepared in 1938 under the Work Progress Administration program detailing the history of a rancho beginning with the Spanish-American land through the U.S. patenting process.

Hoffman Notes -- Summary of information concerning claims made for the Rancho lands from the Appendix listing Table of Land Claims in the Reports of Land Cases …

El Alisal (Hartnell) - Diseños, Glo No. 267, Monterey County, And Associated Historical Documents.

Individual Ranchos in Monterey and SLO Counties

Diseños - Hand-drawn Spanish-Mexican map demonstrating the physical boundaries of land granted to Mexican citizens by the Spanish or Mexican.

Expediente – Hand-written Spanish-Mexican land grant document issued to Mexican citizens in Alta California for land in Alta-California.

Work Progress Administration Abstract (WPA Abstract) – A summary document prepared in 1938 under the Work Progress Administration program detailing the history of a rancho beginning with the Spanish-American land through the U.S. patenting process.

Hoffman Notes -- Summary of information concerning claims made for the Rancho lands from the Appendix listing Table of Land Claims in the Reports of Land Cases …

Encinal Y Buena Esperanza - Diseños, Glo No. 269, Monterey County, And Associated Historical Documents.

Individual Ranchos in Monterey and SLO Counties

Diseños - Hand-drawn Spanish-Mexican map demonstrating the physical boundaries of land granted to Mexican citizens by the Spanish or Mexican.

Expediente – Hand-written Spanish-Mexican land grant document issued to Mexican citizens in Alta California for land in Alta-California.

Work Progress Administration Abstract (WPA Abstract) – A summary document prepared in 1938 under the Work Progress Administration program detailing the history of a rancho beginning with the Spanish-American land through the U.S. patenting process.

Hoffman Notes -- Summary of information concerning claims made for the Rancho lands from the Appendix listing Table of Land Claims in the Reports of Land Cases …

El Potrero De San Carlos - Diseños, Glo No. 286, Monterey County And Associated Historical Documents

Individual Ranchos in Monterey and SLO Counties

Diseños - Hand-drawn Spanish-Mexican map demonstrating the physical boundaries of land granted to Mexican citizens by the Spanish or Mexican.

Work Progress Administration Abstract (WPA Abstract) – A summary document prepared in 1938 under the Work Progress Administration program detailing the history of a rancho beginning with the Spanish-American land through the U.S. patenting process.

Hornbeck Rancho Detail Sheet – A summary sheet generated from a land patent database that details the history of a rancho, along with the various state and federal agency record numbers relating to the rancho.

Bancroft Notes – Document detailing information and documents regarding a …

CañAda De La Carpenteria - Diseños, Glo No. 243, Monterey County, And Associated Historical Documents.

Individual Ranchos in Monterey and SLO Counties

Diseños - Hand-drawn Spanish-Mexican map demonstrating the physical boundaries of land granted to Mexican citizens by the Spanish or Mexican.

Expediente – Hand-written Spanish-Mexican land grant document issued to Mexican citizens in Alta California for land in Alta-California.

Work Progress Administration Abstract (WPA Abstract) – A summary document prepared in 1938 under the Work Progress Administration program detailing the history of a rancho beginning with the Spanish-American land through the U.S. patenting process.

Hornbeck Rancho Detail Sheet (AKA Detail Sheet) – A summary sheet generated from a land patent database that details the history of a rancho, along with the …

Bolsa Nuevo & Moro Cojo - Diseños, Glo No. 245, Apn 125, Apn 127, Apn 129, Apn 131, Apn 133 Monterey County, And Associated Historical Documents.

Individual Ranchos in Monterey and SLO Counties

Diseños - Hand-drawn Spanish-Mexican map demonstrating the physical boundaries of land granted to Mexican citizens by the Spanish or Mexican.

Expediente – Hand-written Spanish-Mexican land grant document issued to Mexican citizens in Alta California for land in Alta-California.

Work Progress Administration Abstract (WPA Abstract) – A summary document prepared in 1938 under the Work Progress Administration program detailing the history of a rancho beginning with the Spanish-American land through the U.S. patenting process.

Hoffman Notes -- Summary of information concerning claims made for the Rancho lands from the Appendix listing Table of Land Claims in the Reports of Land Cases …

El Chamisal - Diseños, Glo No. 536, Monterey County, And Associated Historical Documents.

Individual Ranchos in Monterey and SLO Counties

Diseños - Hand-drawn Spanish-Mexican map demonstrating the physical boundaries of land granted to Mexican citizens by the Spanish or Mexican.

Expediente – Hand-written Spanish-Mexican land grant document issued to Mexican citizens in Alta California for land in Alta-California.

Work Progress Administration Abstract (WPA Abstract) – A summary document prepared in 1938 under the Work Progress Administration program detailing the history of a rancho beginning with the Spanish-American land through the U.S. patenting process.

Hoffman Notes -- Summary of information concerning claims made for the Rancho lands from the Appendix listing Table of Land Claims in the Reports of Land Cases …

El Pescadero (Jacks) - Diseños, Glo No. 280, Monterey County, And Associated Historical Documents.

Individual Ranchos in Monterey and SLO Counties

Diseños - Hand-drawn Spanish-Mexican map demonstrating the physical boundaries of land granted to Mexican citizens by the Spanish or Mexican.

Expediente – Hand-written Spanish-Mexican land grant document issued to Mexican citizens in Alta California for land in Alta-California.

Work Progress Administration Abstract (WPA Abstract) – A summary document prepared in 1938 under the Work Progress Administration program detailing the history of a rancho beginning with the Spanish-American land through the U.S. patenting process.

Hornbeck Rancho Detail Sheet (AKA Detail Sheet) – A summary sheet generated from a land patent database that details the history of a rancho, along with the …

Buena Vista (Estrada) - Diseños, Glo No. 274, Monterey County, And Associated Historical Documents.

Individual Ranchos in Monterey and SLO Counties

Diseños - Hand-drawn Spanish-Mexican map demonstrating the physical boundaries of land granted to Mexican citizens by the Spanish or Mexican.

Expediente – Hand-written Spanish-Mexican land grant document issued to Mexican citizens in Alta California for land in Alta-California.

Work Progress Administration Abstract (WPA Abstract) – A summary document prepared in 1938 under the Work Progress Administration program detailing the history of a rancho beginning with the Spanish-American land through the U.S. patenting process.

Hoffman Notes -- Summary of information concerning claims made for the Rancho lands from the Appendix listing Table of Land Claims in the Reports of Land Cases …

Cienega Del Gabilan - Diseños, Glo No. 243, Monterey County, And Associated Historical Documents.

Individual Ranchos in Monterey and SLO Counties

Diseños - Hand-drawn Spanish-Mexican map demonstrating the physical boundaries of land granted to Mexican citizens by the Spanish or Mexican.

Expediente – Hand-written Spanish-Mexican land grant document issued to Mexican citizens in Alta California for land in Alta-California.

Work Progress Administration Abstract (WPA Abstract) – A summary document prepared in 1938 under the Work Progress Administration program detailing the history of a rancho beginning with the Spanish-American land through the U.S. patenting process.

Hornbeck Rancho Detail Sheet (AKA Detail Sheet) – A summary sheet generated from a land patent database that details the history of a rancho, along with the …

Response To Comment By Faurby, Werdelin And Svenning, Stephen J. O'Brien, Klaus Peter Koepfli, Eduardo Eizirik, Warren Johnson, Carlos Driscoll, Agostinho Antunes, Anne Schmidt-Kuntzel, Laurie Marker, Pavel Dobrynin

Biology Faculty Articles

No abstract provided.

Germline Defects Caused By Smed-Boule Rna-Interference Reveal That Egg Capsule Deposition Occurs Independently Of Fertilization, Ovulation, Mating, Or The Presence Of Gametes In Planarian Flatworms, Jessica Kathryne Steiner, Junichi Tasaki, Labib Rouhana

Biological Sciences Faculty Publications

Few animals are known to lay eggs in the absence of ovulation or copulation, as it is presumably energetically wasteful and subjected to negative selection. Characterization of Smed-boule, a member of the DAZ family of germline RNA-binding proteins, revealed that egg capsule (or capsule) production and deposition occurs independently of the presence of gametes in the planarian flatworm Schmidtea mediterranea. Reduction of Smed-boule expression by RNA-interference (RNAi) causes ablation of spermatogonial stem cells and the inability of ovarian germline stem cells to undergo oogenesis. Although animals subjected to Smed-boule RNAi lose their gametes and become sterile, they continue …

Canada De La Segunda - Diseños, Glo No. 283, Monterey County, And Associated Historical Documents.

Individual Ranchos in Monterey and SLO Counties

Diseños - Hand-drawn Spanish-Mexican map demonstrating the physical boundaries of land granted to Mexican citizens by the Spanish or Mexican.

Expediente – Hand-written Spanish-Mexican land grant document issued to Mexican citizens in Alta California for land in Alta-California.

Work Progress Administration Abstract (WPA Abstract) – A summary document prepared in 1938 under the Work Progress Administration program detailing the history of a rancho beginning with the Spanish-American land through the U.S. patenting process.

Hoffman Notes -- Summary of information concerning claims made for the Rancho lands from the Appendix listing Table of Land Claims in the Reports of Land Cases …

Tales Of The Atom!: An Analysis Of Nuclear Discourage In Early Marvel Comics, Kelly Elizabeth Shepherd

Senior Theses

In 1961 the editor of Atlas Comics, Martin Goodman, approached his nephew and staff writer Stan Lee with a pitch. Goodman wanted Lee to create a super hero team to rival DC Comics’, Justice League of America. Lee came up with the Fantastic Four who debuted in November of 1961. The super hero team led by physicist Bruce Banner was the first of many successful titles from Marvel Comics. Much of the popularity of Marvel Comics stemmed from the company’s focus on the characters rather than only action like other superhero comics at the time. Lee developed characters that …

Challenging Authoritative Perceptions: The Story Of Philip James Evans, Michael Nicklas Goyda

Senior Theses

This senior thesis is an extension on a previous work I have done for Honors Creative Writing (ENGL 360). The story takes you through the early life of Philip James Evans, a young man born in 1976 in Pittsburgh, PA. An alcoholic in remission, he is killed one day and wakes up in a mysterious building which is actually the headquarters of The Illuminati in Purgatory. Philip faces a tough decision: remain dead and await judgment for his wrongdoings and risk being sent to Hell, or work for The Illuminati to pay off the debt of his sins and receive …

The Effects Of Chronic Partial Sleep Deprivation And Chronic Voluntary Alcohol Consumption On Δfos B Accumulation, Kristian Ponder

Masters Theses, 2010-2019

The present study explores the relation between sleep restriction and alcohol use and the neural substrates that result from chronic behaviors. Accumulation of the transcription factors ΔFosB is suggested as a possible outcome of chronic behaviors, such as addiction. Sleep is discussed as possible mediating factor in the relationship between ΔFosB and chronic alcohol consumption. There were four experimental groups in this study: Control (C), Sleep Deprivation only (SD), Alcohol Exposure only (AO), and both sleep deprivation and alcohol exposure (B). Levels of ΔFosB accumulation in the Nucleus Accumbens (NAc) revealed a significant main effect of sleep deprivation, but no …

Prioritizing Eastern Hemlock (Tsuga Canadensis) For Secondary Imidacloprid Treatment Against The Invasive Hemlock Woolly Adelgid (Adelges Tsugae) In Shenandoah National Park, Katelyn Walters

Masters Theses, 2010-2019

Shenandoah National Park (SNP) contains over 20,000 eastern hemlocks (Tsuga canadensis); a foundation species in the southern Appalachian Mountains. Hemlock is shade-tolerant and retains a dense needle canopy year-round, creating a unique microclimate providing habitat for many species. The decline in eastern hemlock from hemlock woolly adelgid (Adelges tsugae; HWA) infestation has negative implications for the overall function of forest ecosystems. The effect of slope aspect and time since imidacloprid insecticide treatment on crown health change and diameter growth of eastern hemlock in SNP was quantified. Data was compared from hemlock trees located on southeastern (SE) and …

The Effect Of Stimulus Location And Initial Posture On The Kinematics Of The Nociceptive Withdrawal Reflex Of The Tail In Intact And Unanaesthetized Rats, Yulhea Kim

Masters Theses, 2010-2019

The nociceptive withdrawal reflex (NWR) is a protective reflex that allows mammals to avoid noxious stimuli by withdrawing the affected area of the body away from the stimulus. Although previous studies on non-human mammals showed that the NWR depends on stimulus location and initial posture, these studies were performed on spinalized or anaesthetized animals, which may yield results differing from intact animals. Therefore, the purpose of this study was to determine whether the kinematics of the NWR of the tail depends on stimulus location and initial posture in intact and unanesthetized animals. The NWR was evoked by heat applied to …

Zn(Ii), Cu(Ii), Sn(Ii), And Ni(Ii) And Other Metal Cations Do Not Prevent The Aggregation Of Hiapp, Charles Hoying

Honors Thesis

The Zn(II) metal ion has been shown to interact with Islet Amyloid Polypeptide (IAPP), a protein implicated in the progression of Type II Diabetes Mellitus, in such a way as to prevent the protein from aggregating into toxic fibers. We set out to find whether other metal ions might similarly prevent IAPP aggregation. Using Thioflavin T (ThT) spectroscopic assays, which measure fluorescence of ThT upon binding to aggregated IAPP, we observed a decrease in aggregation when incubated with Zn(II), Cu(II), Ni(II), and Sn(II). Atomic Force Microscopy (AFM), which can visualize fibril formation, revealed that the metals were not inhibiting IAPP …