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Articles 122671 - 122700 of 256039
Full-Text Articles in Life Sciences
1997, San Luis Obispo Crop Report.
1997, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
1996, San Luis Obispo Crop Report.
1996, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
2001, San Luis Obispo Crop Report.
2001, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
1998, San Luis Obispo Crop Report.]
1998, San Luis Obispo Crop Report.]
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
2005, San Luis Obispo Crop Report.
2005, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
2002, San Luis Obispo Crop Report.
2002, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
2003, San Luis Obispo Crop Report.
2003, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
Synthesis And Biological Activity Of Novel Quorum Sensing Compounds, Joseph Nicholas Capilato
Synthesis And Biological Activity Of Novel Quorum Sensing Compounds, Joseph Nicholas Capilato
Theses and Dissertations
Bacteria communicate with chemical signals in a process known as quorum sensing. This population density-dependent process involves the bacterial production, release and detection of structurally specific small molecules and enables the bacterial pathogen to regulate its virulence on a population-wide level. Using a variety of chemical and biological techniques, I have studied various quorum sensing systems in several bacteria, including Vibrio cholera and Pseudomonas aeruginosa. A key principle of this research involves the design, synthesis and testing of novel compounds for their biological activity. These molecules are typically based off of an initial lead target, which is often identified …
Antiviral Rna Silencing Suppression Activity Of Tomato Spotted Wilt Virus Nss Protein, Tania Ocampo Ocampo, Sergio M. Gabriel Peralta, Nicole Bacheller, Stella Uiterwaal, Aaron Knapp, Alanna Hennen, Daniel Leobardo Ochoa-Martínez, Hernan Garcia-Ruiz
Antiviral Rna Silencing Suppression Activity Of Tomato Spotted Wilt Virus Nss Protein, Tania Ocampo Ocampo, Sergio M. Gabriel Peralta, Nicole Bacheller, Stella Uiterwaal, Aaron Knapp, Alanna Hennen, Daniel Leobardo Ochoa-Martínez, Hernan Garcia-Ruiz
Department of Plant Pathology: Faculty Publications
In addition to regulating gene expression, RNA silencing is an essential antiviral defense system in plants. Triggered by double-stranded RNA, silencing results in degradation or translational repression of target transcripts. Viruses are inducers and targets of RNA silencing. To condition susceptibility, most plant viruses encode silencing suppressors that interfere with this process, such as the Tomato spotted wilt virus (TSWV) NSs protein. The mechanism by which NSs suppresses RNA silencing and its role in viral infection and movement remain to be determined. We cloned NSs from the Hawaii isolate of TSWV and using two independent assays show for the first …
Pharmacologic Inhibition Of Host Phosphodiesterase-4 Improves Isoniazid-Mediated Clearance Of Mycobacterium Tuberculosis, Selvakumar Subbian, Mi-Sun Koo, Liana Tsenova, Vikram Khetani, Jerome B. Zeldis, Dorothy Fallows, Gilla Kaplan
Pharmacologic Inhibition Of Host Phosphodiesterase-4 Improves Isoniazid-Mediated Clearance Of Mycobacterium Tuberculosis, Selvakumar Subbian, Mi-Sun Koo, Liana Tsenova, Vikram Khetani, Jerome B. Zeldis, Dorothy Fallows, Gilla Kaplan
Publications and Research
The lengthy duration of multidrug therapy needed to cure tuberculosis (TB) poses significant challenges for global control of the disease. Moreover, chronic inflammation associated with TB leads to pulmonary damage that can remain even after successful cure. Thus, there is a great need for the development of effective shorter drug regimens to improve clinical outcome and strengthen TB control. Host-directed therapy (HDT) is emerging as a novel adjunctive strategy to enhance the efficacy and shorten the duration of TB treatment. Previously, we showed that the administration of CC-3052, a phosphodiesterase-4 inhibitor (PDE4i), reduced the host inflammatory response during Mycobacterium tuberculosis …
1977, San Luis Obispo Crop Report.
1977, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
1985, San Luis Obispo Crop Report.
1985, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
1991, San Luis Obispo Crop Report.
1991, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
1994, San Luis Obispo Crop Report.
1994, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
Interview With Paul Kilgus, Ben Halpern
Interview With Paul Kilgus, Ben Halpern
Oral History Interviews & Transcripts
No abstract provided.
1989, San Luis Obispo Crop Report.
1989, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
1993, San Luis Obispo Crop Report.
1993, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Agriculture in San Luis Obispo County, California.
1988, San Luis Obispo Crop Report.
1988, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
1990, San Luis Obispo Crop Report.
1990, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
1981, San Luis Obispo Crop Report.
1981, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
1980, San Luis Obispo Crop Report.
1980, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
1989, San Luis Obispo Crop Report.
1989, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
1983, San Luis Obispo Crop Report.
1983, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
1986, San Luis Obispo Crop Report.
1986, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
1995, San Luis Obispo Crop Report.
1995, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
1978, San Luis Obispo Crop Report.
1978, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
Diversity, Structure And Convergent Evolution Of The Global Sponge Microbiome, Torsten Thomas, Lucas Moitinho-Silva, Miguel Lurgi, Johannes R. Bjork, Cole Easson, Carmen Astudillo-Garcia, Julie B. Olson, Patrick M. Erwin, Susanna Lopez-Legentil, Heidi Luter, Andia Chaves Fonnegra, Rodrigo Costa, Peter J. Schupp, Laura Steindler, Dirk Erpenbeck, Jack Gilbert, Rob Knight, Gail Ackermann, Jose V. Lopez, Michael W. Taylor, Robert W. Thacker, Jose M. Montoya, Ute Hentschel, Nicole S. Webster
Diversity, Structure And Convergent Evolution Of The Global Sponge Microbiome, Torsten Thomas, Lucas Moitinho-Silva, Miguel Lurgi, Johannes R. Bjork, Cole Easson, Carmen Astudillo-Garcia, Julie B. Olson, Patrick M. Erwin, Susanna Lopez-Legentil, Heidi Luter, Andia Chaves Fonnegra, Rodrigo Costa, Peter J. Schupp, Laura Steindler, Dirk Erpenbeck, Jack Gilbert, Rob Knight, Gail Ackermann, Jose V. Lopez, Michael W. Taylor, Robert W. Thacker, Jose M. Montoya, Ute Hentschel, Nicole S. Webster
Marine & Environmental Sciences Faculty Articles
Sponges (phylum Porifera) are early-diverging metazoa renowned for establishing complex microbial symbioses. Here we present a global Porifera microbiome survey, set out to establish the ecological and evolutionary drivers of these host–microbe interactions.We show that sponges are a reservoir of exceptional microbial diversity and major contributors to the total microbial diversity of the world’s oceans. Little commonality in species composition or structure is evident across the phylum, although symbiont communities are characterized by specialists and generalists rather than opportunists. Core sponge microbiomes are stable and characterized by generalist symbionts exhibiting amensal and/or commensal interactions. Symbionts that are phylogenetically unique to …
1984, San Luis Obispo Crop Report.
1984, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
1979, San Luis Obispo Crop Report.
1979, San Luis Obispo Crop Report.
San Luis Obispo Crop Reports
Annual report pertaining to agriculture in San Luis Obispo County, California.
The North American Grouse: Their Biology And Behavior, Paul A. Johnsgard
The North American Grouse: Their Biology And Behavior, Paul A. Johnsgard
Zea E-Books Collection
The ten currently recognized species of grouse in North America have played an important role in America’s history, from the famous but ill-fated heath hen, a primary source of meat for the earliest New England immigrants, to the ruffed grouse, currently one of the most abundant and soughtafter upland game birds in more than 40 states and provinces. This book summarizes the ecology, reproductive biology, and social behavior of all ten of the extant North American grouse species. It also describes the current status of grouse populations, some of which are perilously close to extinction. The social behavior of grouse …