Life Sciences Commons^™

Analyzing Ballast Water Treatments, Invasive Species, And Pathogens, And A Decade-Long Analysis On The San Francisco And Baltimore Ports, Jasmin Ibarra-Cortes

Master's Projects and Capstones

Installation of advanced technologies to treat ballast water on ships is necessary to meet current ballast water management standards and reduce the secondary spread of invasive species during intracoastal voyages. This research includes a literature review on non-native aquatic species, particularly diapausing eggs, and available treatment methods for installation. A comparative analysis from 2014 - 2024 on bulker, tanker, and container vessels arriving coastwise to the ports of San Francisco and Baltimore was performed to evaluate treatment installation trends, traffic patterns, and the effectiveness of treatment(s) on targeting diapausing eggs. Use of ultraviolet (UV) radiation combined with filtration has increased …

The Manifestation Of Synesthesia In The Deaf, Hard-Of-Hearing, And Sign Language User Population, Elizabeth Droubi

Undergraduate University Honors Capstones

This capstone project investigated the prevalence and manifestation of synesthesia—a perceptual condition where stimulation in one sensory pathway triggers automatic, involuntary experiences in another—within d/Deaf, hard-of-hearing (DHH), and sign language user populations. Despite an estimated prevalence of over 4% in the general population and findings that many synesthetic experiences are language-based, little is known about how synesthesia presents across different language modalities, including signed languages. This project explored the phenomenon in two phases: an initial online survey assessing the prevalence and characteristics of synesthesia among DHH and signing individuals and follow-up interviews with self-reported synesthetes along with a test-retest procedure …

Trade-Off Between Limonene & Geraniol-Based Reprocessable And Non-Reprocessable Epoxy Thermosets: Role Of Aliphatic Diamines In Polymer Networks Design, Priyankkumar Kanubhai Patel

Electronic Theses & Dissertations

The growing demand for sustainable materials, driven by environmental concerns and the rapid depletion of fossil fuels, has garnered significant attention in the fabrication of bio-based epoxy thermosets as renewable alternatives to petroleum-derived thermosetting polymers. The present study focuses on the synthesis and characterization of epoxy prepolymer resins derived from limonene and geraniol via a two-step process, followed by the fabrication of thermally cross-linked flexible epoxy thermoset films using various traditional aliphatic diamine curing agents, namely 1,2-ethylenediamine (EDA), 1,4-butylenediamine (BDA), and 1,6-hexamethylenediamine (HDA). Additionally, the incorporation of cystamine, a disulfide-containing diamine, enabled the formation of a covalent adaptable network through …

Bio-Based Composites With Enhanced Mechanical Strength And Flame Retardancy, Riya Patel

Electronic Theses & Dissertations

Composites are versatile and useful in many fields, including aerospace, automotive, construction, and healthcare, due to their high mechanical strength. It is common practice to synthesize these materials using petroleum-based chemicals. Nonetheless, in the twenty-first century, scientists are more interested in using renewable resources to create composites. The greatest substitute for petroleum-based chemicals is vegetable oil. It has unsaturated double bonds that are modifiable chemically. In the present study, bio-polyol was synthesized using castor oil, an inedible vegetable oil. A ring-opening process was used to modify it and produce castor oil-based polyol. The synthesized castor oil-based polyol was characterized by …

Kid Eats App: Supporting Parents And Children Cooking Together, Amy S. Muise, Gabrielle A. Longo, Pamela N. Martinez, Umekia R. Taylor, Linda E. Torv, Barbara A. Chamberlin

Journal of Extension

Kid Eats is a free app for iPad encouraging children and parents to cook together at home using fruits and vegetables. A preliminary study with parents and children showed children enjoyed using the app and that it provided useful information to support children’s involvement in the kitchen, including guidance around safety concerns. Every family in the study voluntarily completed at least one of the recipes with their child at least once following the in-person activity. Parents reported that their children actively asked to cook the recipes from the app and felt the app helped increase their time spent cooking with …

Stress-Related Phenotypic Differentiation Identified By Motivational Behaviors In Male Mice, Renee A. Brummels

Honors Thesis

Social stress substantially contributes to psychological disorders, including anxiety, depression, and post-traumatic stress disorder. Recognizing these disorders affect millions, it is essential to understand social stress’s impacts on behavior and how these behaviors vary among affected populations. We address these questions through a social defeat/avoidance paradigm, the Stress-Alternatives Model (SAM), which demonstrates defeat (Stay) and avoidance (Escape) responses across species, including fish, rats, hamsters, and mice. Avoidance of social conflict in the SAM is possible by utilizing escape routes for smaller test mice during aggressive interactions. Additionally, measurements of SAM motivational behaviors, like time near and nose pokes into escape …

Evaluating Simulated Threecornered Alfalfa Hopper (Hemiptera: Membracidae) Damage In Cotton (Malvales: Malvaceae) And Identifying Conducive Environments, Reece Starnes Butler

Theses and Dissertations

This research evaluated the effects of simulated threecornered alfalfa hopper (TCAH), Spissistilus festinus (Say), damage in cotton and aimed to identify environments that may contribute to an increase in TCAH injury. During the 2023 and 2024 growing season, simulated TCAH damage was imposed at 0%, 10%, 20%, 30%, 40%, and 50% at the three and six leaf growth stage. Agronomic data included plant heights, node counts, and plant mapping, which was collected throughout the growing season, while lint yield was recorded at harvest. Damaged plants exhibited reduced plant heights and node counts, with an increase in nodes above cracked boll …

06.16.2025 Ored Connect, Liz Williamson

ORED Newsletter

Email address Matters with SPAN and ARC Forms

Participant Support Costs training for PIs available in Blackboard

Assessing One-Year Health Impacts From Wildfires In Rural Communities: Roles For Extension In Promoting Wildfire Preparedness And Recovery, Marc T. Braverman, Sandi Cleveland Phibbs, Emily Jane Davis, Amanda Rau, Elijah Penner

Journal of Extension

Wildfires can produce health impacts that persist for years in affected communities. This article describes an Extension-led study of health impacts in rural Oregon communities one year after a destructive wildfire. Data collection included key informant interviews (n=36), an online survey (n=80), and three focus group interviews with survivors (n=23). Mental health, exposure to contaminants, physical stress, food insecurity, and other issues were frequently identified health concerns. Survivors’ difficulties in dealing with housing displacement significantly exacerbated health challenges. We describe potential roles for Extension in addressing wildfire risk and mitigating health impacts, including a description of the Oregon Fire Program.

Monoclonal Antibodies Targeting Candida Disrupt Biofilms And Inhibit Growth Across Global Clinical Isolates, Jonothan Rosario-Colon, Karen Eberle, Hong Xin

School of Graduate Studies Faculty Publications

Candida species are a major cause of severe fungal infections, particularly in immunocompromised individuals and hospitalized patients. Among these, Candida auris stands out as an emerging “superbug”, responsible for life-threatening bloodstream infections with mortality rates up to 60%. This multidrug-resistant, hospital-acquired pathogen has been declared a serious global health threat, complicating effective treatment and increasing mortality risks. Our research has identified universal monoclonal antibodies (mAbs) targeting Candida albicans cell wall epitopes, which are highly homologous to those in other pathogenic Candida species, including C. auris. Passive transfer of mAbs—C3.1 (anti-β-1,2-mannotriose) and 9F2 (anti-phosphoglycerate kinase 1)—significantly extended survival and improved fungal …

Effects Of Different Forms Of Dietary Zinc On Weaned Steers When Fed Prior To Weaning, Christopher Lane Addison

Theses and Dissertations

Zinc (Zn) is crucial for many life sustaining processes within the body. Additional Zn is known to be beneficial during certain periods of increased stress. Weaning is one of the most stressful periods of beef calves’ lives. Due to this it was hypothesized that additional zinc in an organic form would increase weight gain and immune response compared to additional zinc in an inorganic form or no added zinc. No differences were found for ADG, Th score, IgG concentration, or mineral concentration among treatments. However, there was a novel and unexpected finding when there was no difference found in preweaning …

Taking Flight: Utilizing Unmanned Aerial Systems To Sample Insects In Soybean, William "Covey" Lockhart

Theses and Dissertations

Insect scouting in soybean is a labor-intensive task but is needed throughout the season to minimize losses. When soybeans are tall, soils are wet, or soybeans are planted in narrow rows, walking through these fields can be difficult. To overcome these limitations of manual sampling, an unmanned aerial vehicle (UAV) sampling platform was developed that can collect insects in a sweep net attached to the bottom of a UAV. This system has been named the “Drone Insect Net Sampling System” (DINSS). Previous research with this system has shown positive correlations to traditional manual sampling methods. To improve this system, modifications …

Effects Of Environmental Stress And Antimicrobials On The Health, Microbiome, And Product Shelf-Life Of Channel And Hybrid Catfish, Guyue Tang

Theses and Dissertations

Two studies investigated various aspects of channel and hybrid catfish production and processing. The first study examined the effects of ammonia stress (15 mg/L vs. 1 mg/L control) on growth performance and fillet quality. While channel catfish demonstrated superior growth, ammonia stress minimally impacted the sensory profiles of both species. Gut microbiota analysis revealed species-specific differences, with Lactococcus lactis dominating hybrid catfish communities. The second study evaluated buffered vinegar treatment (1.5%) on fillet shelf life during refrigerated storage. Vinegar-treated fillets maintained better microbiological quality, with aerobic plate counts remaining below 7 log cfu/g through day 6, while untreated fillets exceeded …

Evaluation Of Plant Growth Regulators On Sweetpotato Slip Propagation, Kerington Lyn Bass

Theses and Dissertations

Sweetpotato production is often impacted by high mortality of slips during transplantation to the field, particularly with greenhouse-grown slips. These slips develop thinner stems, thus being more vulnerable to transplant shock, resulting in reduced establishment. To address this issue, the study evaluated the effects of four plant growth regulators on the morphological and anatomical characteristics of sweetpotato slips. In the first experiment, external growth parameters were recorded over four weeks, followed by post-harvest assessments of plant and root material. In the second experiment, the widths of various stem structures in stained cross-sections of slip stems were measured. Results showed that …

The Effects Of Ataxin-1 Overexpression In The Central Nervous System On Specific Behavioral And Physiological Characteristics Of Drosophila Melanogaster, Sydney Davis

Theses and Dissertations

Spinocerebellar ataxia type 1 (SCA1) is a dominantly inherited neurodegenerative disease caused by a CAG repeat expansion in the ataxin-1 gene, which results in an abnormally long polyglutamine tract. Similarly, overexpression of wildtype Ataxin-1 (wt-Atx-1) in Drosophila melanogaster leads to neurodegeneration, reduced lifespan, and impaired negative geotaxis. Observations include disruptions in sleep-wake cycles, increased oxidative stress biomarkers (like protein carbonyls), and dysregulation of developmental genes such as armadillo (arm) and nemo kinase (nmo). Additionally, elevated expression of SUMOylation-related genes (Aos-1, Uba2, and dSmt3 or dSumo) and increased SUMO protein levels indicate enhanced SUMOylation in the brain. Quantitative analysis of neuronal …

Evaluating The Efficacy Of Functional Feed Additives In Broilers With Or Without A Live Coccidiosis Vaccine Challenge, Dalton Gerard Dennehy

Theses and Dissertations

Functional feed additives, such as probiotics, prebiotics, and phytogenics, have seen increased usage in commercial poultry production due to their ability to improve growth performance, meat yield, and overall health status. Therefore, the objective of this research was to evaluate the efficacy of functional feed additives in broilers with or without an enteric challenge induced via a live coccidiosis vaccine (LCV). In the first study (Chapter II), broilers were raised on used litter without an LCV challenge and fed varying levels of a multi-strain Bacillus-based probiotic in the starter phase (1x or 2x dose). Reduced performance was observed in early …

Impact Of An Automated Brush System On Intensively Managed Lactating Dairy Cattle Behavior, Production, And Stress Physiology, Allison Lyn Griffin

Theses and Dissertations

The dairy industry has increasingly prioritized improving animal welfare for intensively housed cows. This study evaluated the effects of environmental enrichment (EE) using an automated brush system on stress physiology, behavior, and productivity of lactating dairy cows. Fifty-nine pregnant and lactating dairy cows were divided into two groups: CON (no brush) and TRT (automated brush system). Saliva samples were collected to measure cortisol concentrations, and behaviors were monitored in the morning (07:00 h - 11:00 h) and evening (19:00 h - 23:00 h) using high-resolution cameras. The results indicated that cows with brush access had lower cortisol concentrations, suggesting reduced …

Exploring Sexual Dimorphism In A Drosophila Melanogaster Model Of Spinocerebellar Ataxia Type 1, Madelyn Hunter

Theses and Dissertations

Neurodegenerative diseases affect over 36 million people and are characterized by loss of motor control, neuronal degradation, and behavioral changes. The most common of these diseases exhibit sexually dimorphic effects. In this study, Spinocerebellar ataxia type 1 (SCA1) was modeled in the Drosophila central nervous system using the yeast hybrid UAS/GAL4 system. Locomotor activity and clock gene expression was monitored for male and female SCA1 and control flies. Clock genes such as per, tim, Clk, and cyc were monitored over a 24-hour period using qRT-PCR, and distinct sexual dimorphism was detected in locomotor activity and in gene expression for SCA1 …

Biomechanics Of Softball Pitching And The Relationship Between Functional Field Tests And Pitching Performance, Joshua Spencer Johnson

Theses and Dissertations

Over 2 million people in the United States play softball alone, yet softball literature in exercise science and biomechanics is still sparse. Research that exists for softball pitching has focused on injury mechanisms and prevention, with a small portion of the literature reporting on performance. Studies have reported evidence suggesting that vertical ground reaction forces of the stride leg are related to pitch velocity. However, no studies have investigated the role of the stride leg during the initial launch phase of the pitch. Research has investigated kinematics such as pelvic and thoracic rotation during the pitch, but no research has …

Evaluating The Use Of Translucency Score As An Effective Parameter Of Eggshell Quality, Cassidy Autumn Morris

Theses and Dissertations

The objective of this thesis was to determine if an egg’s translucency score (TS) could be used as an effective predicting parameter to determine eggshell quality in both broiler breeders and commercial laying hens. In broiler breeders, it was determined that TS could be used as an effective predicting parameter for eggshell thickness (P< 0.001) and L* scores (P< 0.001). It was also found that the supplementation of organically sourced trace minerals could significantly decrease the TS of eggs, resulting in a better-quality eggshell (P< 0.001). In two different aged commercial laying hen experiments, there was no conclusive evidence for TS to be a predictive parameter of eggshell quality throughout the storage period. It was found, however, that the storage period did significantly increase the TS throughout storage in both experiments (P< 0.001).

The Effect Of X-Ray Irradiation Technology On Salmonella Spp. And Quality Parameters Of Ready-To-Bake Chocolate Chip Cookie Dough, Kala Grace Morris

Theses and Dissertations

Salmonella contamination in cookie dough poses a threat to consumers. This study investigated the effect of X-ray irradiation on Salmonella-inoculated ready-to-bake chocolate chip cookie dough and its impact on dough quality. A Salmonella cocktail (~10 log CFU/g) was prepared and inoculated into cookie dough samples (~6.5 log CFU/g) and then treated with X?ray irradiation (0.25, 0.5, and 1 kGy). Salmonella decreased by 1.15, 1.79, and 2.49 log CFU/g, at an exposure of 0.25, 0.5, and 1 kGy, respectively. Quality parameters (pH, aw, and colorimetry) were evaluated for two brands. No statistical difference (P>0.05) in pH was observed for Brand …

Ecology And Management Of Alligatorweed (Alternanthera Philoxeroides) And An Associated Thrips Biological Control Agent (Amynothrips Andersoni), Samuel Alec Schmid

Theses and Dissertations

Alligatorweed (Alternanthera philoxeroides), native to South America, is a highly invasive aquatic macrophyte that is globally distributed and particularly problematic in the southeastern United States. In the United States, alligatorweed management has a long history, particularly of chemical and biological control. Alligatorweed management saw early success with a South American flea beetle (Agasicles hygrophila), but this agent’s utility has waned. Despite the long history of alligatorweed invasion, several important research questions remain, and the research in this dissertation seeks to answer some of these questions. This research focuses on multiple and diverse aspects of alligatorweed biology, ecology, and management: (1) …

Assessing The Kinematics And Kinetics About The Knee With An Isokinetic Dynamometer And Force Plates During Field-Based And Lab-Based Trials., Samantha Ann Searles

Theses and Dissertations

The incidence rate in knee injuries has increased over the last 20 years, with women at a 2-8 times higher incidence rate compared to men. This is likely a result of lower neuromuscular control of the trunk, generating less hip muscle activation, and more reliance on the quadriceps, alongside reduced hip, knee, and dorsiflexion angles, paired with increased knee valgus angles, ground reaction forces (GRF), hip adduction, and knee rotation upon landing from jumps. The focus of this study is to determine if knee kinetics and kinematics during field- and lab-based trials are associated with knee injury predictors. Theoretically, if …

Combined Effect Of Chitosan And Lemon Essential Oil-Infused Slush Ice On The Shelf Life Of Channel Catfish, Dianna Wilson

Theses and Dissertations

The objective of this research was to investigate the biopreservative effects of chitosan and lemon essential oil in slush ice treatments on the microbial shelf life of refrigerated catfish fillets. Catfish fillets were stored in slush ice treatments containing chitosan (CH), lemon essential oil (LO), a combination (CH+LO), water (CTRL), and no slush (NS) for three d at 4 C, then stored at 4C for twelve d post-slush. The growth of background microflora in catfish fillets treated with CH and CH+LO was reduced (P<0.05), maintaining total aerobic counts below 4.5 log CFU/g, while the control reached spoilage levels (>7 log CFU/g) by Day 6. Chitosan effectively extended the microbial shelf life but lowered pH, …

Myxozoan Diversity And Life Cycles In Catfish Production Ponds In Mississippi, Usa, Ethan Woodyard

Theses and Dissertations

Catfish aquaculture is a critical industry in the United States and Mississippi in particular. The industry is beset by depredation, rising feed costs, competition with imports, and loss to disease. Chief among these is the myxozoan parasite and causative agent of proliferative gill disease, Henneguya ictaluri. In chapter 2, novel molecular markers for greater resolution in species identification of these parasites are provided, allowing more robust life cycle inference, species-level identifications, and inference of evolutionary relationships through molecular phylogenetic analyses. Chapters 3–5 apply the approaches developed in Chapter 2 to a broad array of taxa beyond catfish-infecting Henneguya spp. These …

Evaluating The Feeding Value Of Almond Hulls And The Supplementation Of Carbohydrases On Performance, Egg Quality, Nutrient Digestibility And Intestinal Health In Lsl-Lite Hens, Nelly Giovanna Cribillero Chuquihuaccha

Theses and Dissertations

Almond hulls (AH) are a by-product of the almond nut processing rich mainly in insoluble fiber. Addition of fiber in the diet has been shown positive results in performance in poultry. However, scientific literature on the use of AH in poultry is limited. The objective of this dissertation was to determine the effect of the supplementation of ground AH and cellulase-xylanase carbohydrase enzyme (E) inclusions on performance, egg quality, ileal nutrients digestibility, jejunum gene expression and ceca microbiota of Lohmann LSL-Lite pullets and laying hens from 0 to 70 weeks of age. Chapter I describe the knowledge on the composition …

Assessment Of Pagp Gene Function In Avian Pathogenic Escherichia Coli Pathogenicity Using Different Challenge Models, Hailey Fugate

Theses and Dissertations

Avian pathogenic Escherichia coli (APEC) is a leading cause of morbidity and mortality in poultry, contributing an estimated $40 million in annual losses in the U.S. broiler industry alone, and contributing to growing concerns over antibiotic resistance. This study investigated the role of the pagP gene, which encodes a lipid A palmitoyl transferase involved in immune evasion, using both a broiler chick and embryo challenge model. Deletion of pagP significantly reduced mortality and lesion severity in broilers, indicating its role in APEC pathogenicity. However, in embryos, pagP deletion had minimal effects on survival and bacterial colonization, suggesting alternative virulence mechanisms …

Evaluation Of Broiler Performance And Processing Metrics Through Sodium Bisulfate Application To Litter And Varying Inclusions In Feed, Samantha Suzanne Plocher

Theses and Dissertations

Poultry producers must continuously evaluate current practices and determine new ones to further optimize broiler production. Sodium bisulfate (SB) is used as a poultry litter amendment (SBL), but also in human food to control pH; thus, initiating interest for SB in feed (SBF) for performance and gut health benefits. This thesis utilized common diets varying in SBF (Chapters II and III) and SBL (Chapter II; SBL1- d 0 and SBL2 – d 0 and 18) to optimize 40 d broiler performance, litter quality, and d 41 processing metrics. For Chapter II, d 0 SBL1 dramatically lowered litter pH, while minimally …

High Kynu Expression Is Associated With Poor Prognosis, Keap1/Stk11 Mutations, And Immunosuppressive Metabolism In Patient-Derived But Not Murine Lung Adenocarcinomas, Ling Cai, Thomas J Rogers, Reza Mousavi Jafarabad, Hieu Vu, Chendong Yang, Nicole Novaresi, Ana Galán-Cobo, Luc Girard, Edwin J Ostrin, Johannes F Fahrmann, Jiyeon Kim, John V Heymach, Kathryn A O'Donnell, Guanghua Xiao, Yang Xie, Ralph J Deberardinis, John D Minna

Faculty, Staff and Student Publications

Background/Objectives: We aimed to discover genes with bimodal expression linked to patient outcomes, to reveal underlying oncogenotypes and identify new therapeutic insights in lung adenocarcinoma (LUAD).

Methods: We performed meta-analysis to screen LUAD datasets for prognostic genes with bimodal expression patterns. Kynureninase (KYNU), a key enzyme in tryptophan catabolism, emerged as a top candidate. We then examined its relationship with LUAD mutations, metabolic alterations, immune microenvironment states, and expression patterns in human and mouse models using bulk and single-cell transcriptomics, metabolomics, and preclinical model datasets. Pan-cancer prognostic associations were also assessed.

Results: Model-based clustering of KYNU expression outperformed median-based dichotomization …

Climate Resilience For Organic Vegetable Growers In The Midwest: Views, Needs, And Priorities Of Technical Service Providers, Natalie Hoidal, Greta Gramig, James Dedecker, Nicholas Frillman, Katie Black, Sarah Hayward, Rue Genger

Journal of Extension

As organic vegetable production becomes increasingly important in Upper Midwest food systems, Extension programs and partners must rise to the challenge of supporting growers with climate resilience. These growers are uniquely vulnerable to climate impacts, and addressing this challenge requires a networked approach. We report on a needs assessment and social network analysis process with technical service providers across the region to define the challenges, needs, and opportunities for building individual and institutional capacity to address climate change with growers. Results highlighted several focus areas, including improved communication, better access to funding, sound information, and cultural appropriateness.