Life Sciences Commons^™

The Effect Of Metronome Use On Heart Rates And Rpe For Drum Corps Percussionists, Danielle Dye, Vaughn Barry

International Journal of Exercise Science

International Journal of Exercise Science 9(4): 412-418, 2016. The purpose was to evaluate if playing a musical selection without a metronome would affect the heart rates and rate of perceived exertion for drum corps percussionists. Heart rate and RPE values were collected from 11 battery and 12 front ensemble members from one drum corps. The music consisted of two portions of the show at different tempos of 96 and 176 beats per minute. The music was performed at "standstill" with the battery members lined up behind the front ensemble marching, but not moving around or carrying their instruments. The participants …

Adolescents’ Perception Of The Psychosocial Factors Affecting Sustained Engagement In Sports And Physical Activity, James Gavin, Madeleine Mcbrearty, Kit Malo, Michael Abravanel, Tatiana Moudrakovski

International Journal of Exercise Science

International Journal of Exercise Science 9(4): 384-411, 2016. The purpose of this study was to explore adolescents’ perceptions of psychosocial influences – personal characteristics, environmental factors and behavioural undertakings – influencing their prolonged involvement in sports and physical activity (PA). A qualitative approach was adopted wherein 16 adolescents (8 boys, 8 girls; mean age 15.9 years), who had been physically active for at least the last 8 years, and sixteen adults identified as their ‘parents’ or ‘guardians’ participated in semi-structured interviews. Interviews were transcribed verbatim and coded using the HyperRESEARCH software. Data were analysed using thematic analysis procedures. Four main …

The Effect Of Skinfold On The Assessment Of The Mean Power Frequency At The Fatigue Threshold, Alyssandra N. Baniqued,, Jorge M. Zuniga, Thomas C. Strunc, Katie M. Keenan, Agrini K. Boken, Jeff J. Anderson

International Journal of Exercise Science

International Journal of Exercise Science 9(4): 376-383, 2016. The purpose of this study was to determine if the amount of subcutaneous tissue over the quadriceps affects the assessment of mean power frequency at the fatigue threshold (MPF_FT). It was hypothesized that greater skinfold values will result in lower power outputs associated to the MPF_FT. Fourteen adults (Mean ± SD age = 20.7 ± 0.99; body weight = 72.8 ± 12.6 kg) performed an incremental cycle ergometry test to exhaustion while surface electromyographic (EMG) signals were measured from the vastus lateralis. The skinfold thickness of each leg …

How Do The Social Benefits And Costs Of The Patent System Stack Up In Pharmaceuticals?, Daniel J. Gifford

Journal of Intellectual Property Law

This paper explores the workings of the patent system in the context of the generation of new pharmaceutical products. First it identifies the relevant characteristics of the patent system and its relation to the market. The paper concedes that, in general, the patent system is probably the best way of generating new technology, in substantial part because that system uses the market to provide both incentives and rewards. The paper also identifies downsides of this patent/market system: deadweight loss and the unresponsiveness of that patent/market system to the needs of the poor. The paper then explores the social costs and …

Big Data Analysis Bio 439/539, Michael Cerbo

Library Impact Statements

No abstract provided.

Environmental Leadership In Practice Evs 505x, Michael Cerbo

Library Impact Statements

No abstract provided.

Proprotein Convertase Processing Enhances Peroxidasin Activity To Reinforce Collagen Iv, Selene Colon, Gautam Bhave

Biology Student Research

The basement membrane (BM) is a form of extracellular matrix that underlies cell layers in nearly all animal tissues. Type IV collagen, a major constituent of BMs, is critical for tissue development and architecture. The enzyme peroxidasin (Pxdn), an extracellular matrix-associated protein, catalyzes the formation of structurally reinforcing sulfilimine cross-links within the collagen IV network, an event essential to basement membrane integrity. Although the catalytic function of Pxdn is known, the regulation of its activity remains unclear. In this work we show through N-terminal sequencing, pharmacologic studies, and mutational analysis that proprotein convertases (PCs) proteolytically process human Pxdn at Arg-1336, …

Canine Filamentous Dermatitis Associated With Borrelia Infection, Marianne J. Middelveen, Gheorghe M. Rotaru, Jody L. Mcmurray, Katherine R. Filush, Eva Sapi, Jennie Burke, Agustin Franco, Lorenzo Malquori, Melissa C. Mcelroy, Raphael B. Stricker

Biology and Environmental Science Faculty Publications

Background: Although canine clinical manifestations of Lyme disease vary widely, cutaneous manifestations are not well documented in dogs. In contrast, a variety of cutaneous manifestations are reported in human Lyme disease caused by the spirochete Borrelia burgdorferi. A recently recognized dermopathy associated with tickborne illness known as Morgellons disease is characterized by brightly-colored filamentous inclusions and projections detected in ulcerative lesions and under unbroken skin. Recent studies have demonstrated that the dermal filaments are collagen and keratin biofibers produced by epithelial cells in response to spirochetal infection. We now describe a similar filamentous dermatitis in canine Lyme disease. Methods and …

Stem Course Design In Higher Education Bes 501, Michael Cerbo

Library Impact Statements

No abstract provided.

Subcellular And In-Vivo Nano-Endoscopy, Surya Venkatasekhar Cheemalapati, John Winskas, Hao Wang, Karthik Konnaiyan, Arseny Zhdanov, Alison Roth, Swamy Rakesh Adapa, Andrew Deonarine, Rays H. Y. Jiang, Anna Pyayt

Chemical, Biological and Materials Engineering Faculty Publications

Analysis of individual cells at the subcellular level is important for understanding diseases and accelerating drug discovery. Nanoscale endoscopes allow minimally invasive probing of individual cell interiors. Several such instruments have been presented previously, but they are either too complex to fabricate or require sophisticated external detectors because of low signal collection efficiency. Here we present a nanoendoscope that can locally excite fluorescence in labelled cell organelles and collect the emitted signal for spectral analysis. Finite Difference Time Domain (FDTD) simulations have shown that with an optimized nanoendoscope taper profile, the light emission and collection was localized within ~100 nm. …

Acetylsalicylic Acid Supplementation Improves Protein Utilization Efficiency While Vitamin E Supplementation Reduces Markers Of The Inflammatory Response In Weaned Pigs Challenged With Enterotoxigenic E. Coli, Jae Cheol Kim, Bruce P. Mullan, John L. Black, Robert J E Hewitt, Robert J. Van Barneveld, John R. Pluske

Animal production and livestock research articles

Background

This experiment was conducted to test the hypothesis that vitamin E (Vit E) and acetylsalicylic acid (ASA), a cyclooxygenase-2 (COX-2) inhibitor, will additively reduce the production of the immunosuppressive molecule prostaglandin E2 (PGE2) and hence reduce inflammatory responses in weaner pigs experimentally infected with an enterotoxigenic strain of E. coli.

Methods

The experiment was conducted in a research facility with 192 individually-housed male weaner pigs (Landrace × Large White) weighing 6.6 ± 0.04 kg (mean ± SEM). The pigs were experimentally infected with an enterotoxigenic strain of E. coli and were allocated to a 2 × 3 factorial …

Biologically-Variable Rhythmic Auditory Cues Are Superior To Isochronous Cues In Fostering Natural Gait Variability In Parkinson’S Disease, Dobromir Dotov, S. Bayard, Valérie Cochen De Cock, Christian Geny, Valérie Driss, G. Garrigue, Benoit G. Bardy, Simone Dalla Bella

Journal Articles

Introduction

Method

Effect Of Timing Of Hip Extension Assistance During Loaded Walking With A Soft Exosuit, Ye Ding, Fausto A. Panizzolo, Christopher Siviy, Philippe Malcolm, Ignacio Galiana, Kenneth G. Holt, Conor J. Walsh

Journal Articles

Background

Recent advances in wearable robotic devices have demonstrated the ability to reduce the metabolic cost of walking by assisting the ankle joint. To achieve greater gains in the future it will be important to determine optimal actuation parameters and explore the effect of assisting other joints. The aim of the present work is to investigate how the timing of hip extension assistance affects the positive mechanical power delivered by an exosuit and its effect on biological joint power and metabolic cost during loaded walking. In this study, we evaluated 4 different hip assistive profiles with different actuation timings: early-start-early-peak …

Tgf-Β Signaling: New Insights Into Aortic Aneurysms, Sean E. Thatcher

Pharmacology and Nutritional Sciences Faculty Publications

No abstract provided.

Assisted Tree Migration In North America: Policy Legacies, Enhanced Forest Policy Integration, And Climate Change Adaptation, Adam Wellstead, Michael Howlett

Department of Social Sciences Publications

The weight of much expert forest management opinion is that issues such as climate change can be effectively addressed only if forest policy-making moves from a purely sectoral focus and undergoes a shift to a more integrated multi-issue, multi-sector policy-making process. This is because credible adaptation policies in the sector require greatly enhanced multi-sectoral policy integration if they are to succeed. But this requirement may be beyond the capacity of many countries to deliver. This article explores the integration challenges faced by forest policy-making in Canada and the United States and uses the case of Assisted Tree Migration (ATM) to …

Weights And Balances: Integrating Models For Prevention And Response To Southern California Offshore Oil Spills, Carmen Watts Clayton, Amoret Bunn

STAR Program Research Presentations

Licensing offshore oil and gas reserves in the United States waters are overseen by the U.S. Department of the Interior’s Bureau of Safety and Enforcement (BSEE). The licensing application includes planning for any worst-case oil spill scenario between BSEE and the applicant based on lessons learned from historic offshore spills such as the Deepwater Horizon (2010), Exxon Valdez (1989), and the Union Oil Platform Blowout (1969). The process for planning to respond to oil spills involves coordination with multiple agencies, trustees, and stakeholders to ensure that oil spill responses consider multiple factors, including ecologically sensitive species, commercial transportation and fisheries, …

Soil Moisture On Soledad Ridge In Santa Rosa Island, Channel Islands National Park, Carrie Fong, Kathryn Mceachern, Ken Niessen

STAR Program Research Presentations

Santa Rosa Island is one of the Channel Islands off the coast of southern California. Before the island was heavily grazed, Santa Rosa Island is thought to have had large stands of island oak trees, Quercus tomentella, that provided a critical source of water for the ecosystem by creating a “cloud forest”. Wind-borne fog collects on the leaves, branches, and twigs of the island oaks and other native shrubs. Once the water condenses it drips, falls, and soaks into the soil. Introducing cattle and especially sheep to the island has damaged the ecosystem and nearly decimated Santa Rosa Island …

Studying The Effects Of Serpentine Soil On Adapted And Non-Adapted Species Using Arduino Technology, Kiana Saniee, Edward Himelblau, Brian Paavo

STAR Program Research Presentations

Abstract: Serpentine soils are formed from ultramafic rocks and are represent an extreme environment for plants. Serpentine soils are unique in that they carry high concentrations of heavy metals, are nutrient deficient, particularly in calcium, and have poor water retention capabilities. Although these soils constitute harsh conditions for plant growth, there are a number of species that are adapted and even endemic to serpentine soil. Water retention by commercial potting mix was compared with serpentine soil. Also, serpentine adapted and non-adapted species were grown in both soil treatments and physiological data were collected. We used the Arduino electronic platform to …

A Study Of Defensive Mechanisms Employed By Two Species Of Nudibranchs Using Toxicity And Unpalatability Analyses, Sean Youn

Independent Study Project (ISP) Collection

Nudibranchs are marine invertebrates that have developed an intriguing defense mechanism, including warning coloration and the use of chemicals accumulated through their sponge diet. The goal of this study was to determine whether the strength of chemical defenses differs between dietary and accumulated secondary metabolites for two species: Glossodoris vespa and Ceratosoma brevicaudatum. First, NMR spectroscopy was used to not only identify specific compounds in the mantle (outer covering) and the viscera (gut) but also to analyze the possibility of nudibranch species transporting more toxic compounds for defensive purposes. Next, toxicity (brine shrimp) and palatability (Palaemon shrimp) assays were used …

Editorial: Food Legume Diversity And Legume Research Policies, Matthew W. Blair, Jing Wu, Shumin Wang

Agricultural and Environmental Sciences Faculty Research

No abstract provided.

Evaluation Of Common Bean (Phaseolus Vulgaris L.) Genotypes For Drought Stress Adaptation In Ethiopia, Kwabena Darkwa, Daniel Ambachew, Hussein Mohammed, Asrat Asfaw, Matthew W. Blair

Agricultural and Environmental Sciences Faculty Research

Drought stress linked with climate change is one of the major constraints faced by common bean farmers in Africa and elsewhere. Mitigating this constraint requires the selection of resilient varieties that withstand drought threats to common bean production. This study assessed the drought response of 64 small red-seeded genotypes of common bean grown in a lattice design replicated twice under contrasting moisture regimes, terminal drought stress and non-stress, in Ethiopia during the dry season from November 2014 to March 2015. Multiple plant traits associated with drought were assessed for their contribution to drought adaptation of the genotypes. Drought stress determined …

Qtl And Candidate Genes Associated With Common Bacterial Blight Resistance In The Common Bean Cultivar Longyundou 5 From China, Jifeng Zhu, Jing Wu, Lanfen Wang, Matthew W. Blair, Zhendong Zhu, Shumin Wang

Agricultural and Environmental Sciences Faculty Research

Common bacterial blight (CBB), caused by Xanthomonas axonopodis pv. phaseoli and Xanthomonas fuscans subsp. fuscans (Xff), is a worldwide disease of common bean (Phaseolus vulgaris L.). Longyundou 5, a Chinese cultivar in the Mesoamerican gene pool of common bean, displays resistance to the Xff strain XSC3-1. To identify the genetic mechanisms behind this resistance, we crossed Long 5 with a susceptible genotype to develop a mapping population of F2 plants. Plant resistance to CBB was identified at 14 and 21 days after inoculation with Xff strain XSC3-1. A major QTL at 14 and 21 days after inoculation …

An Excitatory Cortical Feedback Loop Gates Retinal Wave Transmission In Rodent Thalamus, Yasunobu Murata, Matthew T. Colonnese

Pharmacology and Physiology Faculty Publications

Spontaneous retinal waves are critical for the development of receptive fields in visual thalamus (LGN) and cortex (VC). Despite a detailed understanding of the circuit specializations in retina that generate waves, whether central circuit specializations also exist to control their propagation through visual pathways of the brain is unknown. Here we identify a developmentally transient, corticothalamic amplification of retinal drive to thalamus as a mechanism for retinal wave transmission in the infant rat brain. During the period of retinal waves, corticothalamic connections excite LGN, rather than driving feedforward inhibition as observed in the adult. This creates an excitatory feedback loop …

Hiv-1 Integrates Widely Throughout The Genome Of The Human Blood Fluke Schistosoma Mansoni., Sutas Suttiprapa, Gabriel Rinaldi, Isheng J Tsai, Victoria H. Mann, Larisa Dubrovsky, Hong-Bin Yan, Nancy Holroyd, Thomas Huckvale, Caroline Durrant, Anna V Protasio, Tatiana Pushkarsky, Sergey Iordanskiy, Matthew Berriman, Michael I. Bukrinsky, Paul J. Brindley

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Schistosomiasis is the most important helminthic disease of humanity in terms of morbidity and mortality. Facile manipulation of schistosomes using lentiviruses would enable advances in functional genomics in these and related neglected tropical diseases pathogens including tapeworms, and including their non-dividing cells. Such approaches have hitherto been unavailable. Blood stream forms of the human blood fluke, Schistosoma mansoni, the causative agent of the hepatointestinal schistosomiasis, were infected with the human HIV-1 isolate NL4-3 pseudotyped with vesicular stomatitis virus glycoprotein. The appearance of strong stop and positive strand cDNAs indicated that virions fused to schistosome cells, the nucleocapsid internalized and the …

To Fish Or Not To Fish? What Effect Do California’S Marine Protected Areas Have On Up-And-Coming Kellet’S Whelk Fishery?, Jennifer Greene

STAR Program Research Presentations

Kellet’s whelk, Kelletia kelletii, were observed at sample sites throughout their range from Baja California, Mexico, to Monterey, CA to determine patterns of population density. Sample sites in each region were either located within California marine protected areas where take of the Kellet’s whelk in prohibited, or in non-protected areas where the whelks can be fished both commercially and recreationally. Kellet’s whelk population density was compared between all MPA and non-MPA sample sites. These mean densities were also found for sites in Santa Barbara and San Diego near active fishing ports and compared to data from the same sites collected …

Testing Predictions Used To Build An Agrivoltaics Installation On A Small-Scale Educational Model, Katie Kinney, Rebecca Minor, Greg Barron-Gafford

STAR Program Research Presentations

Models are valuable tools for explaining and testing systems. Small-scale models can be especially useful for educational purposes. For models to be useful, they have to accurately depict the larger system that they are describing. A novel man-made system, known as an agrivoltaic structure, is being constructed at Biosphere 2 near Oracle, Arizona. The word agrivoltaic is a combination of agriculture and photovoltaics, or solar farming. My research involved creating a small-scale version of this system for educational purposes. The model of this system tested two predictions: that plants will grow better in the shade of a panel and that …

The Nih-Niaid Schistosomiasis Resource Center At The Biomedical Research Institute: Molecular Redux., James J Cody, Wannaporn Ittiprasert, André N Miller, Lucie Henein, Margaret M Mentink-Kane, Michael H. Hsieh

Urology Faculty Publications

Schistosomiasis remains a health burden in many parts of the world. The complex life cycle of Schistosoma parasites and the economic and societal conditions present in endemic areas make the prospect of eradication unlikely in the foreseeable future. Continued and vigorous research efforts must therefore be directed at this disease, particularly since only a single World Health Organization (WHO)-approved drug is available for treatment. The National Institutes of Health (NIH)-National Institute of Allergy and Infectious Diseases (NIAID) Schistosomiasis Resource Center (SRC) at the Biomedical Research Institute provides investigators with the critical raw materials needed to carry out this important research. …

The Lli Chronicle Volume 7 Number 3, Nova Southeastern University

Lifelong Learning Institute Newsletters

No abstract provided.

Eelgrass/Macroalgae Discussion Primer For Tac Activities 2016-2017, Piscataqua Region Estuaries Partnership

PREP Reports & Publications

See also: "Eelgrass Distribution and Biomass in the Great Bay Estuary for 2015" http://scholars.unh.edu/prep/354

"Eelgrass Distribution in the Great Bay Estuary for 2014" http://scholars.unh.edu/prep/352/

The issue of eelgrass and macroalgae in the Great Bay Estuary (GBE) is extremely important and complex. The purpose of this document is to clarify issues and questions to make for a more productive and informed discussion.

Mechanisms Of Comorbidities Associated With The Metabolic Syndrome: Insights From The Jcr:La-Cp Corpulent Rat Strain, Abdoulaye Diane, W David Pierce, Sandra Kelly, Sharon Sokolik, Rebecca Hutcheson, Petra Rocic, Spencer Proctor

NYMC Faculty Publications

Obesity and its metabolic complications have emerged as the epidemic of the new millennia. The use of obese rodent models continues to be a productive component of efforts to understand the concomitant metabolic complications of this disease. In 1978, the JCR:LA-cp rat model was developed with an autosomal recessive corpulent (cp) trait resulting from a premature stop codon in the extracellular domain of the leptin receptor. Rats that are heterozygous for the cp trait are lean-prone, while those that are homozygous (cp/cp) spontaneously display the pathophysiology of obesity as well as a metabolic syndrome (MetS)-like phenotype. Over the years, there …