Life Sciences Commons^™

Machine Learning Applications For Berth Allocation Optimization In Major Red Sea Ports: A Multi-Port Analysis, Mohammed H. Alshareef

Journal of King Abdulaziz University: Marine Science

Efficient berth allocation remains a critical challenge in Red Sea port operations, particularly given the diverse operational capabilities across the region's ports. The research utilized historical operational data from 147,892 berth allocation instances across these ports spanning 2019--2023. A deep learning model was developed using four dense layers with ReLU activation functions, incorporating vessel characteristics, weather patterns, and operational constraints. The model's performance was validated through comparison with traditional allocation methods using real-time port operation data. Port selection criteria included geographical distribution along the Red Sea, varying levels of technological adoption, and willingness to share operational data for research purposes. …

Lifecycle Of Greater Wax Moth Galleria Mellonella (Lepidoptera: Pyralidae) And Its Control By Natural Products, Tahani A. Alzahrani, Hanan S. Alyahya, Shatha I. Alqurashi, Jazem A. Mahyoub

Journal of King Abdulaziz University: Meteorology, Environment and Arid Land Agriculture

The great wax moth (Galleria mellonella) is a major pest that affects honeybee colonies, causing serious damage to the honeycomb and disrupting beekeeping operations. This paper aims to review the life cycle of this insect and the natural control strategies used to manage its populations. This paper examines the different stages of growth of the great wax moth, including the stages of eggs, larva, pupae, and adults. The life cycle of this insect depends largely on environmental conditions, especially temperature, humidity and food quality, in addition, this paper focuses on natural control strategies, such as the use of plant extracts …

Mecanismos De Participación En Temas Ambientales En Colombia, Martha Rocío Castro Rodríguez, Felipe Ramírez Cortázar, Sara Milena Niño Montero

Ciencias Agropecuarias

Mecanismos de participación en temas ambientales en Colombia es un producto editorial, de divulgación y apropiación social del conocimiento, desarrollado en el proyecto de investigación “Participación política en ciudades de Colombia, Italia y Guatemala: un estudio mixto sobre su relación con la anomia y la autoeficacia política en jóvenes”, en el marco de la V convocatoria interna - periodo 2023-1 UCundinamarca Generación Siglo 21.

Assessment Of Dominant Shark And Ray Species And Their Size At Brondong And Muncar Ports, East Java, Indonesia, Tri Djoko Lelono, Gatut Bintoro, Arief Setyanto, M. Arief Rahman, Desy Setyoningrum, Naufal Hilda Bahtiar, Hanifa Ramadhani, Tawang Firmansyah, Hasan Syaiful Rizal

Journal of King Abdulaziz University: Marine Science

Shark and ray species are both limited in number and distribution and require time to mature and reproduce, making these species extremely vulnerable to mass exploitation as a resource. Based on the identification results, Muncar Port Banyuwangi had 26 species from 490 ray samples, and Brondong Port Lamongan had 28 species from 1830 ray samples. Fifteen species of rays were found only in Brondong, 17 species of rays were found only in Muncar, and as many as 13 were found in the two sample sites. As for sharks in Muncar, 38 out of 679 species were Brondong samples and 22 …

Innovations In Shipbuilding: A Comprehensive Review Of Material Selection, Corrosion Management, And Environmental Considerations, Oumaima Bouanani, Sara Sandabad, Moulay El Houssine Ech-Chhibat

Journal of King Abdulaziz University: Marine Science

The shipbuilding industry, a cornerstone of global maritime operations, oversees vessel lifecycles from design through commissioning. This article delves into the industry's complex role in facilitating global trade, driving technological advancements, and prioritizing sustainability and safety. The harsh marine environment-marked by salinity, temperature extremes, and mechanical stresses-necessitates resilient and durable vessel structures. Consequently, the careful selection of materials is crucial for ensuring vessel longevity and performance under stringent safety and environmental standards. Recent breakthroughs in shipbuilding materials, including high-strength steel, composites, and lightweight alloys, have transformed the industry. Innovative solutions, such as shape memory alloys and eco-friendly composites, are designed …

Identifying And Analysing Coastal Landforms In Ar Rāyis, Saudi Arabia: Insights From Sentinel Data And Field Studies, Omar A. Alharbi

Journal of King Abdulaziz University: Marine Science

This study examines the coastal geomorphology of the Ar Rāyis coastal zone on the eastern Red Sea coastal plain, along with the processes underpinning this geomorphology. Coastal areas feature various landforms, including beaches, intertidal flats, khawrs (lagoons), sand spits, sand dunes, sabkhas (salt marshes), coral reefs, wadis, raised coral reef terraces, and alluvial terraces. These landform features suggest rapid alterations in coastal conditions. Furthermore, the analysis of Sentinel-2B data via digital processing reveals a range of natural land covers, with field investigations confirming the results. The supervised classification methods assisted in distinguishing between regions of deep and shallow water, while …

Hubungan Ketersediaan Fasilitas Jamban Sehat Di Rumah Tangga Terhadap Kejadian Diare Pada Balita Menurut Analisis Data Sdki Tahun 2017 Di Wilayah Pedesaan Papua, Edgina Dhafia Callista, Arina Qonita, Bonyca Verlina, Pratiwi Pamarta Endah Jatmika

Jurnal Nasional Kesehatan Lingkungan Global

Diarrhea is a disease that commonly affects toddlers and is one of the top causes of death among children aged 1–59 months. In pedesaan areas, diarrhea remains a serious public health issue, with recorded cases reaching as high as 17,811. Purpose of this study is to explore the relationship between the availability of healthy toilet facilities in households and the incidence of diarrhea among toddlers. The research used a cross-sectional study design, utilizing secondary data obtained from the 2017 Indonesian Demographic and Health Survey (SDKI). A total of 222 samples that met the predetermined inclusion criteria were selected through random …

From Differentiation To Disease: Cyclin C Directly Coordinates Transcription And Mitochondrial Dynamics, Alicia Campbell

Theses and Dissertations

Organelle crosstalk is essential for coordinating cellular responses to various external cues, including stress and differentiation. Two key organelles, the nucleus and mitochondria, engage in extensive crosstalk to manage responses to a range of environmental and developmental signals. Complex processes such as stem cell differentiation and neuronal development rely on organelle crosstalk. Both processes integrate changes in gene expression with cytosolic and organellar remodeling. However, it remains unclear how these two complex processes are coordinated to achieve the desired outcome. This project concentrates on cyclin C (CCNC), a component of the Mediator Kinase Module (MKM), and its role in directly …

The Effort To Improve Students’ Problem-Solving Ability: Physics E-Modules For High School Students, Hidayatullah Hana Putra, Edi Supriana, Nasikhuddin Nasikhuddin, Annisa U. Yana, Suhailee Sohnui

Jurnal Pendidikan Sains

Physics teachers in Indonesia still face obstacles during learning, such as students who are less active and have difficulty in solving physics problems. The physics learning media used are also still not very interesting and are not based on authentic problem solving. Therefore, this study focuses on the development of PBL-based e-modules on work and energy to improve the physics problem-solving abilities of high school students. This research and development used the ADDIE design and was tested on 90 high school students in High School 1 Sumber Pucung Malang in the 2022/2023 academic year. The questionnaire instrument was used in …

Ethnoscience-Based Science Learning Through Composite Board Making Utilizing Eggshell Waste And Water Hyacinth Fiber (Eichornia Crassipes), Asep Khaidir Arpan, Yulia Sukmawardani, Pina Pitriana, Ade Yeti Nuryantini

Jurnal Pendidikan Sains

The demand for boards continues to increase every year, while overexploitation of wood leads to environmental degradation and forest loss. On the other hand, eggshell and water hyacinth waste continues to grow without optimal utilization. This research aims to make composite boards based on eggshell waste and water hyacinth fibers and analyze the potential of ethnoscience in science learning. This research used a qualitative descriptive method with a literature and documentation study approach. The materials used in this experiment are eggshell waste, water hyacinth fiber, and polyester resin. The composite board was made by mixing water hyacinth fiber and eggshell …

Contextual Approach To Improve Problem Solving Skills In Ipas Subject At Elementary School: A Study Development Of Teaching Materials, Nur Hidayah, Sumarno Sumarno, Joko Siswanto

Jurnal Pendidikan Sains

The objective of this study is to assess the validity, practicality, and efficacy of instructional materials. We refer to this research as research and development, with a focus on the creation of teaching materials. The research design proposed by Borg and Gall consists of six steps: identification of potential and difficulties, data collecting, product design, design validation, design revision, and product trial. The utilized instruments comprise expert and practitioner validity sheets, teacher and student response surveys, and validation sheets for teaching materials and modules, as well as pretest and posttest questions. Experts performed the validity assessment, attaining a score of …

Teaching Materials Containing Kse To Support Character Education In Mathematics Subjects In Elementary Schools, Kunaenah Kunaenah, Rasiman Rasiman, Bagus Ardi Saputro

Jurnal Pendidikan Sains

The purpose of the study was to determine the validity, practicality, and effectiveness of teaching materials containing KSE to support character education in mathematics lesson content. This study employs a development research approach based on Borg and Gall's research design. The subjects of the study were in class V at public elementary school Kaliboyo. The data collection instruments used were validity sheets, response questionnaires, validation sheets, and observation sheets. The findings show that experts carried out the validity test, achieving a value of 93.30% in the very valid category. The practicality test results were derived from various sources: students' questionnaires, …

Development Of Differentiated Teaching Modules With A Scientific Approach To Improve Elementary School Students’ Science Literacy, Supriyanto Supriyanto, Joko Sulianto, Achmad Buchori

Jurnal Pendidikan Sains

The study aim is to determine the validity, practicality, and effectiveness of teaching materials. This type of research involves the development and creation of teaching module products. The research design used is ADDIE (Analysis, Design, Development, Implementation, Evaluation). The instruments used are validity sheets for experts and practitioners, teacher response questionnaires, teaching module validation sheets, and pretest and posttest questions. The findings show that experts conducted the validity test, achieving a score of 92.22 in the very valid category. The practicality test was obtained from the teacher questionnaire, which was stated as practical with an average value of 91.25, and …

Differentiated Teaching Module Using Problem Solving Model: Numerical Ability Of Elementary School Students, Risa Alifatin, Agus Sutono, Ida Dwijayanti

Jurnal Pendidikan Sains

This study aims to develop a differentiated teaching module using the problem-solving model that is valid, practical, and effective to improve students' numerical abilities. This study uses the ADDIE Model research and development approach. The sample in this study was class III of elementary school Tenggulangharjo as an experimental class totaling 22 students and class III of elementary school Karangtengah as a control class totaling 19 students. Data analysis used the t-test and N-Gain test. The study found that (1) the average validity score of the three parts of the Differentiated Teaching Module was 3.74, which is 93.62%, placing it …

Erratum: Culture Harder: Use More Specimen To Increase Methicillin-Resistant Staphylococcus Aureus Culture Yield Relative To Pcr, Arvette E. Mitchell, Arpit P. Patel, Jennifer Dicandilo, Zachary W. Rebollido, Matthew Pettengill

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

During the copyediting stage of production an error was introduced to the title of this article. This resulted in misspelling of the word ‘specimen’ in the title of the published version of the record. The correct title is ‘Culture harder: use more specimen to increase methicillin-resistant Staphylococcus aureus culture yield relative to PCR.’

Previously the title was ‘Culture harder: use more specimens to increase methicillinresistant Staphylococcus aureus culture yield relative to PCR.’

The version of record was updated to reflect this correction.

We apologise for the inconvenience.

Analysis Of Students' Creative Thinking Skills In Learning Hydrocarbons By Using Daily Life-Based Practicum Method, Yenni Kurniawati, Laras Dyaz Handayani, Dea Ramadani, Nurhikmah Sari

Jurnal Pendidikan Sains

Creative thinking skill is a competence of the 21st century that is needed very much and needs to be increased by utilizing chemistry in life. This research aimed at analyzing student creative thinking skills in experimental and control groups and finding out the effect of the daily life-based practical work learning method on student creative thinking skills. This research was conducted in the eleventh grade at High School 1 Pekanbaru on the hydrocarbon lesson. The quasi-experimental method was used in this research with pretest-posttest and non-equivalent control group designs. The instruments used in this research were essay tests, observation, and …

Exploring Students’ Perceptions Of Science Laboratory Practices: A Comparative Study Between Rural And Urban Schools, Safrida Dwiningsih, Ina Lestari, Roma Ismi, Sri Wahyu Rahmadina, Masdalena Sinaga, M. Rahmad

Jurnal Pendidikan Sains

This study aims to analyze students' perceptions of the implementation of science laboratory practicums at public middle school 020 Pekanbaru and public middle school 7 Pangkalan Kuras, Riau Province. Using a quantitative survey method, this study involved 75 student respondents. The instrument used was a questionnaire consisting of 26 statements, analyzed descriptively. The results show that students' perceptions of the preparation, implementation, and conclusion stages of the practicum fall into the "good" category, with urban schools having a higher percentage. In conclusion, the implementation of practicums in urban schools is better than in rural schools, bringing attention to the need …

Digital Comic Learning Media (E-Comic) To Increase Student Learning Interest In Reaction Rate Material At High School, Berliana Afsohin Nabila, Achmad Lutfi

Jurnal Pendidikan Sains

This study aims to develop digital comic learning media that is effective in increasing students' interest in learning about reaction rate material, focusing on the media's validity, practicality, and overall effectiveness. This research utilizes the research and development method with the ADDIE model. Research instruments were used, including validity sheets to assess the media's validity, student activity observations, and student response questionnaires to evaluate the media's practicality, as well as student interest questionnaires and learning outcomes to measure the effectiveness of the learning media. The findings show that validity results showed a mode score of 4, indicating a very valid …

Analysis Of Misconceptions In Learning Biology Mutation Material At High School, Fitri Hayati Kurnia, Tri Wahyu Agustina, Wahyuni Handayani

Jurnal Pendidikan Sains

This research aims to analyze student misconceptions regarding mutation material in class XII. The research method uses a descriptive approach with mixed methods, which combines qualitative and quantitative methods. Qualitative data was obtained through interviews with biology teachers, while quantitative data was obtained through questionnaires and essay tests on students. The research results indicate that the material that students like is growth and development, while the material they don't like is gene mutation and genetic material. Students' misconceptions occur due to preconception aspects, associative thinking, and a lack of understanding of genetic concepts. It was found that students' understanding of …

Integration Of Mechanism-Driven Computational Modeling And Public Data Resources For Chemical Toxicity Assessment, Elena Chung

Theses and Dissertations

Regulatory toxicology depends primarily on animal testing, which limits throughput, mechanistic interpretability, and applicability to human-relevant endpoints. This dissertation presents computational approaches that integrate publicly available bioactivity data with machine learning to support chemical safety evaluation. Oral carcinogenicity was modeled using curated chemicals from the US Environmental Protection Agency’s Integrated Risk Information System (IRIS) and activity data from over 1,900 PubChem assays. Quantitative structure-activity relationship (QSAR) models trained on statistically prioritized assays demonstrated strong predictive performance and were applied to rank the carcinogenic potential of more than 16,000 compounds. Hepatotoxicity was evaluated using a hybrid modeling approach that combined structural …

Antibiofilm Activity Of Amylases Isolated From The Bacteria Associated With The Soft Coral Sarcophyton Trocheliophorum, Asmaa Marshoud Al Harbi, Mamdoh T Jamal, Sathianeson Satheesh

Journal of King Abdulaziz University: Marine Science

Amylases are one of the important enzymes with tremendous biotechnological applications. In this study, the amylase enzyme producing bacterial strains associated with the soft coral Sarcophyton trocheliophorum was isolated and identified. The amylases were produced in a specific growth medium and the stability was tested under different pH and temperature conditions. The crude amylases were tested for the antibiofilm activity against two biofilm-forming bacterial strains. The amylase enzyme extracted from two bacterial strains (KAU-AS1 and KAU-AS3) showed good activity in the antibiofilm activity assays. The amylases reduced the growth and attachment of the biofilm bacteria. Also, the amylase enzymes degraded …

Morphological Observations Of Ophioderma Hybridum (Echinodermata: Ophiuroidea) From Western Of Libya, Najla Mohamed Abushaala, Edris Mansour, Ignazio Sparacio, Abdulfattah Elfituri

Journal of King Abdulaziz University: Marine Science

The distribution of the species of Ophioderma in the Mediterranean is still incompletely known. In this paper, Ophioderma hybridum (Ophiuroidea, Ophiodermatidae) is reported for the first time from the coast of Tajura, in the southern Mediterranean Sea, Libya. This recently described species was until now known only from the coast of Tunisia. Description of external appearance and taxonomic characteristics: Specimens had a dark reddish brown body colour on disc and arms, the radial shields not covered by granules. As a result of these morphological observations, O. hybridum is added to the Ophiuroidea fauna of the Libyan coast, southern Mediterranean Sea, …

Isolation And Importance Of Endophytic Actinomycetes Of Some Red Sea Algae And Their Biological Activities, Najla Ali Alburae

Journal of King Abdulaziz University: Marine Science

Endophytic Actinomycetes attract scientist's attention and in particular, endophytes from marine algae were documented and showed many biological activities that maintain ecological balance in various habitats that solve many health problems. This research aimed at the development of antimicrobial and antioxidant agent from endophytic Actinomycetes. Three seaweed algal samples were collected from the Red Sea Umluj corniche, nestled in northwestern of Saudi Arabia and identified as Ulva lactuca (Chlorophyta), Dictyota dichotoma (Phyaephyta) and Gelidium sp. (Rhodophyta). The collected algal samples were washed, surface sterilized, cut into small squares for Endophytic Actinomycete isolation on Starch nitrate medium containing 10% NaCl. Twelve …

Accumulation And Distribution Of Microplastic Particles In Recent Coastal Sediments From Specific Areas Of The Syrian Coast And Determination Of Medium Energy, Samer Ghadeer, Yousef Rslan

Journal of King Abdulaziz University: Marine Science

Despite the numerous benefits plastics have brought to our daily lives, they have also introduced many unexpected and serious environmental challenges, particularly for marine environments, their ecosystems, and sediments. This research holds significant importance as it addresses microplastic pollution, a pressing contemporary issue that demands solutions. It marks the first study of its kind on the Syrian coast, utilizing sediments to identify and quantify microplastics, as well as to determine their sizes and the primary human activities contributing to their spread. A comprehensive study was conducted on sediment samples from specific areas along the Syrian coast-Wadi Qandel, Banias, and Al-Mantar-to …

Knowledge Of Hiv Transmission And Prevention Among University Students In Pakistan: A Cross-Sectional Study, Muhammad Saleem, Sajid Masood, Shahid Hussain

Journal of Bioresource Management

HIV/AIDS remains a significant public health problem internationally, with young adults being especially at risk because of behavioral and knowledge deficits. In Pakistan, cultural inhibitions and suboptimal health education are the main reasons for limited awareness, particularly among university students. This study had the objectives of determining the knowledge level about HIV transmission and prevention among undergraduate students in Kohsar University Murree (KUM) and to investigate correlations with salient demographic variables. A cross-sectional survey was carried out among 510 students aged 18-27 years through a pre-validated, standardized questionnaire with 12 knowledge-based items. Descriptive statistics and Chi-square tests were utilized to …

Production And Characterization Of Biodiesel From Malapari Seed Oil (Pongamia Pinnata L.): Evaluation Of Quality Parameters Based On The Indonesian National Standard (Sni) 04-7182-2015, Desi Adriyanti Nina Taebenu, Ni Luh Arpiwi, Ida Ayu Astarini

Makara Journal of Science

This study produced biodiesel from Malapari seed oil (Pongamia pinnata L.) by optimizing the esterification and transesterification processes. The objectives of this study were to determine the sulfuric acid (H₂SO₄) catalyst concentration in the esterification reaction that can reduc the free fatty acid (FFA) content of the seed oil to ≤2%, analyze the oil to methanol molar ratio (i.e.,1:6, 1:9, and 1:12) and KOH concentration (i.e.,2%, 4%, and 6%) that will produce the highest biodiesel yield, and evaluate the quality of the produced biodiesel according to the Indonesian National Standar (SNI) 04-7182-2015. The research was …

Effect Of Mercury Dose Variation On Growth And Nitrate Reductase Activity In Aquarius Palifolius (Nees & Mart.) Christenh. & Byng, Tsurayya Nurhanifah, Dwi Umi Siswanti

Makara Journal of Science

Mercury, a byproduct of mining, can harm the environment. One method to reduce this impact is through phytoremediation. This study used the Mexican sword (Aquarius palifolius), a plant with the potential to absorb and accumulate mercury. The aim of this study was to examine the effect of mercury stress on nitrate reductase activity, which plays a role in plant productivity, and to assess its impact on growth parameters, including plant height growth rate, leaf length, and number of leaves. Three-month-old A. palifolius plants obtained from rice fields in Sleman were treated with mercury at doses of 0, 14, …

Metabolic And Physiological Regulation In C. Elegans: Insights Into Sperm Activation And Peroxisome-Mediated Longevity, Yash Flora

LSU Doctoral Dissertations

Organelle dynamics lie at the heart of cellular signaling and metabolic regulation, orchestrating physiological processes such as reproduction and aging across the lifespan. In this dissertation, I investigate how organelle-based signaling coordinates sperm activation and modulates organismal aging in the nematode Caenorhabditis elegans. I identify SPIN-4, a previously uncharacterized Spinster family transporter, as a key regulator of spermiogenesis. SPIN-4 is strongly expressed in developing sperm, localizes to the plasma membrane, and promotes sperm activation by facilitating the export of sphingosine-1-phosphate (S1P). Loss of spin-4 results in defective pseudopod formation, reduced motility, and compromised fertility, phenotypes that can be rescued …

Bayesian-Weighted Mendelian Randomization Reveals Sleep Apnea Syndrome Mediates The Bmi-Chronic Pain Link, Wenbao Shi, Jing Luo, Liu Yang, Dalin Chen, Yongqin Zhang, Jun Peng, Kurt Ruetzler, Manyun Sun, Hua Jin

Faculty, Staff and Student Publications

Background: Body mass index (BMI) has a complex association with a variety of chronic pain conditions, which may be influenced by sleep apnea syndrome (SAS). However, the role of SAS within the causal pathway linking BMI to chronic pain remains unconfirmed. This study explored whether and to what extent SAS serves as a mediator between BMI and chronic pain using Bayesian-weighted Mendelian randomization (BWMR) techniques.

Methods: This study utilized genome-wide association study (GWAS) summary data for BMI (N=461,460) and SAS (N=476,853; based on ICD-10 code diagnostic registries) from the IEU OpenGWAS database, along with chronic pain GWAS data (ICD-10 code-based …

Phase Ii Basket Trial Of Dual Anti-Ctla-4 And Anti-Pd-1 Blockade In Rare Tumors (Dart) Swog S1609: Pancreatic Neuroendocrine Neoplasm (Pnen) Cohort, Sandip Pravin Patel, Jillian Fisher, Young Kwang Chae, Luisa Solis Soto, Anup Kasi, Bhavana Konda, Mark Walshauser, Edwin Parra, Jiexin Zhang, Caroline Duault, Edgar Gonzalez-Kozlova, Ganiraju Manyam, Jianhua Zhang, Hong Chen, Dzifa Yawa Duose, Caddie Laberiano Fernandez, Raja Luthra, Gheath Al-Atrash, Seunghee Kim-Schulze, Holden T Maecker, Ignacio I Wistuba, Sacha Gnjatic, J Jack Lee, Jianjun Zhang, Christine M Magner, Helen X Chen, Elad Sharon, Megan Othus, Christopher W Ryan, Charles Blanke, Cara L Haymaker, Razelle Kurzrock

Faculty, Staff and Student Publications

Purpose: SWOG S1609 Dual Anti-CTLA-4 and anti-PD-1 blockade in Rare Tumors (DART) studied the efficacy of ipilimumab combined with nivolumab across multiple rare tumor types. We report the results of the pancreatic neuroendocrine neoplasm (PNEN) cohort.

Experimental design: Treatment consisted of ipilimumab 1 mg/kg intravenously every 6 weeks with nivolumab 240 mg intravenously every 2 weeks. The primary endpoint was overall response rate (ORR) (Response Evaluation Criteria In Solid TumorsRECIST V.1.1). Secondary endpoints include progression-free survival (PFS), overall survival (OS), and toxicity. Clinical benefit rate (includes ORR plus stable disease (SD)>6 months was examined. Correlative …