Life Sciences Commons^™

Effectiveness Of Exercise-Based Rehabilitation In Chronic Fatigue Syndrome: A Systematic Review And Meta-Analysis, Antonio De Vera Martín, Alberto Díaz Salazar, Isidro Miguel Martín Pérez, Sebastián Eustaquio Martín Pérez

International Journal of Exercise Science

International Journal of Exercise Science 18(5): 495-530, 2025. Chronic Fatigue Syndrome is a complex and debilitating disorder characterized by persistent fatigue, musculoskeletal pain, sleep disturbances, and cognitive impairments. The global prevalence is estimated between 0.2% and 0.4%, affecting over 17 million individuals worldwide, with an estimated burden exceeding 40,000 cases in Spain. Despite the exploration of exercise-based rehabilitation as a therapeutic strategy, its clinical efficacy remains a subject of ongoing debate. This study aims to evaluate the effectiveness of exercise-based rehabilitation relative to conventional treatments in improving functional capacity and alleviating fatigue among adults with CFS A systematic review and …

Enhancing Inclusivity In Sports: A Focus On Adaptive Synergy For Disabled Athletes, Lawrence W. Judge, Matt Moore, Aidan Biddle, Adam Smith, Donald L. Hoover

International Journal of Exercise Science

International Journal of Exercise Science 18(1): 470-494, 2025. Sport science serves many crucial functions in facilitating improvements in human performance, including advancing inclusivity. This may be realized through the conceptual framework of Adaptive Synergy, which integrates Adapted Physical Activity for athletes with physical disabilities while simultaneously optimizing athletic performance for all individuals. This paper introduces the Adaptive Synergy conceptual framework to sport science, applying this cross-disciplinary concept to biomechanics, exercise physiology, sport psychology, and neuroscience to more specific application of adaptive techniques and methods, which are essential to improving both accessibility and innovation in sports. Key areas of focus include …

Transformer Decoder-Enhanced Swin Unetr For Multi-Organ Semantic Segmentation On Openkbp: Improving Radiotherapy Planning Accuracy, Zainab Adnan Jwad, Israa Hadi Ali

Karbala International Journal of Modern Science

Accurate segmentation of organs-at-risk (OARs) in head and neck CT scans is crucial for radiotherapy planning. The CNN-based decoder limitation of Swin UNETR hinders its capacity to process meaningful information from multiple organ positions essential for accurate medical segmentation. The proposed Transformer Decoder-enhanced Swin UNETR model targets the OpenKBP dataset multi-organ segmentation through its dedicated design for this purpose. The model utilizes transformers along with cross-attention approaches in its decoder to improve segmentation mask outputs through analysis of extensive global information. The model gets additional feature representation power through the addition of squeeze-and-excitation (SE) blocks linked with spatial attention mechanisms …

Computational Approach: 3d-Qsar, Molecular Docking, Molecular Dynamics Simulation Investigations, Drug- Like-Ness, And Dft Score Evaluation Of A Potential Novel And Retrosynthesis Of Some Tr-H Derivatives As Streptococcus Pneumoniae Drug., Belaidi Mustapha, Tchouar Noureddine, Djelilate Mohammed, Saleh Bufarwa, Dalal K. Thbayh

Karbala International Journal of Modern Science

Streptococcus pneumoniae is the main source of hospital-acquired pneumonia and meningococcal pneumonia in children, adults, and the elderly, especially the immunocompromised. Recently, it has attracted the attention of many research studies around the world as a potential target for remediation. TR-H are considered SP antibacterial agents, as they can inhibit. To describe their mode of action and to identify new antibacterial drugs against Streptococcus pneumoniae exhibiting the TR-H scaffold, the present work included 3D-QSAR, in- silico pharmacokinetic evaluation and molecular simulation modelling of TR-H. Using an atom-based method for quantitative structure-activity relationship (QSAR) study, a comprehensive 3D-QSAR model …

Potential Economic Impact Of Grapevine Phylloxera (Hemiptera: Phylloxeridae) On Western Australian Winegrapes, David C. Cook, Andrew S. Taylor, Peter S. Gardiner, Rodrigo Pires, Hamish L R Mckirdy, Karen W. Holmes, Helen Spafford

Viticulture Research Articles

Grapevine phylloxera Daktulosphaira vitifoliae Fitch (Hemiptera: Phylloxeridae) has been present in Australia for almost 150 years but has not spread to south-west Western Australia, in part due to the relative isolation of the region. Recent improvements in tourist access, with interstate flights now arriving at Busselton Margaret River Airport, raise concerns about potential phylloxera introductions via wine tourism. In this paper, we simulate the potential economic impact on the Western Australian winegrape industry following a hypothetical arrival event in the Margaret River wine region. We use soil texture maps to assess the suitability of winegrape-growing areas to phylloxera establishment and …

Skin Cancer Diagnosis Utilizing Hybrid Discrete Cosine Transform And High-Performance Convolutional Neural Networks, Mohammed M. Abo-Zahhad, Mohammed Abo-Zahhad

Mansoura Engineering Journal

Detecting skin cancer early and accurately is crucial for successfully treating this potentially fatal disease. Enhancing the accuracy of visual inspection techniques is often necessary to improve clinical decision-making and increase the chance of successful treatment outcomes. In this research, high-performance deep learning (DL) models for automated skin cancer categorization and early skin cancer diagnosis screening are developed and evaluated in conjunction with the discrete cosine transform (DCT). For this purpose, features are extracted from medical images using both techniques. The DCT is used for feature extraction and dimensionality reduction, while deep learning (DL) trains fully connected models for classification …

Sexual And Vegetative Recruitment Of Trembling Aspen Following A High-Severity Boreal Wildfire, Denyse A. Dawe, Ellen Whitman, Michael Michaelian, Alan J. Tepley, Marc-André Parisien

Aspen Bibliography

Background High-severity fire is rare in trembling aspen-dominated forests of the boreal region. The post-fire recruitment strategy of aspen, by either vegetative suckering or sexually (i.e., by seed), has considerable implications for subsequent forest structure, genetic diversity, and ecological resilience to shifting climatic and disturbance regimes. In this study, we take advantage of the unique opportunity provided by the Chuckegg Creek Wildfire Fire (310,000 ha) in northern Alberta, Canada, which burned at high severity through aspen stands before and after spring green-up, to document how phenology, fire severity, and stand characteristics affect recruitment one year following the fire.

Results We …

The Role Of Cephalic Mechanosensory Bristles In Flight Initiation Of The Oleander Hawkmoth, Daphnis Nerii, Maitri Manjunath

Theses and Dissertations

During flight, insects sense air movement past their bodies via sensory bristles distributed all over their body. These bristles provide mechanosensory feedback to their nervous system, thereby modulating wing motion to cope with ambient wind conditions. In many insect systems including locusts, moths, etc., flight can be rapidly initiated by stimulating a set of bristles called cephalic bristles on their head. Rapid initiation of flight requires diverse, distributed flight-related reflexes to be simultaneously activated.

Thus, we hypothesized that cephalic bristles directly and simultaneously trigger diverse flight-related reflexes. We tested this hypothesis using the Oleander hawkmoth, Daphnis nerii, as our study …

Effects Of Fibrogenic And Non Fibrogenic Nanomaterials On Cellular And Molecular Responses In Thp-1 Macrophage, Adedayo E. Oyerinde

Biotechnology Theses

Traditional toxicological testing of nanomaterials is often low-throughput and time-consuming. Here, we aimed to develop an economically viable in vitro assay to prescreen nanomaterials with fibrogenic potential. To this end, we tested the generation of reactive oxygen species (ROS) as well as cytokines (pro- and anti-inflammatory) by macrophages following treatment with fibrogenic and non-fibrogenic nanomaterials. Both classes of nanomaterials induced ROS indistinguishably, suggesting that ROS production doesn’t predict nanomaterial fibrogenicity. We observed higher levels of IL1β and IL6 in macrophages treated with fibrogenic nanomaterials. Analysis of single-cell RNA-Sequencing data of fibrotic lungs from rodents and humans revealed overexpression of Brain …

Understanding Host-Pathogen Interactions Using The Caenorhabditis Elegans – Orsay Virus Experimental Model, Chika Fujii

Arts & Sciences Graduate Student Theses and Dissertations

Over an evolutionary timeline, viruses have evolved ways to exploit biochemical pathways of the host for their propagation, whereas host organisms developed mechanisms to recognize virus infection and cope with them. Consequently, a better understanding of the different host factors involved in virus replication could provide insights into potential biological pathways or molecules for therapeutic targeting. Furthermore, detailed dissection of the mechanisms of virus sensing could reveal fundamentally important aspects of virus sensing that are evolutionarily conserved to mammals and offer insights into potentially underexplored areas of research. The C. elegans experimental model offers a useful platform for studying evolutionarily …

Cost-Effective Solutions For High-Throughput Enzymatic Dna Methylation Sequencing, Amy Longtin, Marina M. Watowich, Baptiste Sadoughi, Rachel M. Petersen, Sarah F. Brosnan, Kenneth Buetow, Qiuyin Cai, Cayo Biobank Research Unit, Vanderbilt University, Michael D. Gurven, James P. Higham, Heather M. Highland, Yi-Ting Huang, Hillard Kaplan, Thomas S. Kraft, Yvonne A. L. Lim, Jirong Long, Amanda D. Melin, Michael J. Montagne, Jamie Roberson, Kee Seong Ng, Michael L. Platt, India A. Schneider-Crease, Jonathan Stieglitz, Benjamin C. Trumble, Vivek Venkataraman, Ian J. Wallace, Jie Wu, Noah Snyder-Mackler, Angela Jones, Alexander G. Bick, Amanda J. Lea

ESI Publications

Characterizing DNA methylation patterns is important for addressing key questions in evolutionary biology, development, geroscience, and medical genomics. While costs are decreasing, whole-genome DNA methylation profiling remains prohibitively expensive for most population-scale studies, creating a need for cost-effective, reduced representation approaches (i.e., assays that rely on microarrays, enzyme digests, or sequence capture to target a subset of the genome). Most common whole genome and reduced representation techniques rely on bisulfite conversion, which can damage DNA resulting in DNA loss and sequencing biases. Enzymatic methyl sequencing (EM-seq) was recently proposed to overcome these issues, but thorough benchmarking of EM-seq combined with …

Multicomponent Parenteral Lipid Emulsions Do Not Prevent Liver Injury In Neonatal Pigs With Obstructive Cholestasis, Greg Guthrie, Caitlin Vonderohe, Valeria Meléndez Hebib, Barbara Stoll, Douglas Burrin

Children’s Nutrition Research Center Staff Publications

Biliary atresia (BA) is a pediatric liver disease that often necessitates parenteral nutrition (PN) to support growth due to impaired liver function. While soy-based lipid emulsions (SLE) are commonly used in PN, they may contribute to cholestatic liver injury. In contrast, mixed lipid emulsions (MLE) show promise in preventing cholestasis in infants without BA, potentially by restoring bile flow. However, their effectiveness in patients of complete bile duct obstruction, as seen in BA, remains uncertain. To explore the potential benefits of MLE in BA, we utilized a neonatal pig model of bile duct ligation (BDL). Pigs underwent either BDL or …

The Joint Association Of Diet Quality And Sleep Regularity With Incident Cardiovascular Disease In The Multi-Ethnic Study Of Atherosclerosis, Kaitlin S Potts, Claire Veldkamp, Alexis C Wood, Erin D Michos, Raymond Noordam, Tianyi Huang, Susan Redline, Heming Wang

Children’s Nutrition Research Center Staff Publications

Background/objectives: Diet quality and sleep regularity both influence cardiovascular disease (CVD) risk and may influence each other, but there is scarce evidence for their joint or interacting associations in relation to CVD. We assessed these associations in the Multi-Ethnic Study of Atherosclerosis (MESA).

Methods: Participants free of CVD with valid diet and sleep measures in 2010-2013 were included and followed through 2020 for detection of incident CVD (188 events detected over 8.8 years among 1782 participants; 55% women). Sleep timing and duration regularity were assessed via the intra-individual SD of sleep onset time and duration across 5- to 7-day actigraphy. …

Renal Patients’ Perception Of Self-Efficacy Through Rapport And Trust With Registered Dietitians, Michelle Denise Broussard

Walden Dissertations and Doctoral Studies

End stage renal disease requires dietary education and behavior modifications to manage the condition. The purpose of this quantitative study was to investigate the role of rapport and trust between the patients and registered dietitians and its impact on self-efficacy. The study was implemented over 12 weeks in multi-site dialysis units in urban Georgia. The health belief model was used as the framework to explain the participants’ desire toward self-efficacy. Data were obtained for the 14-item Health Care Relationship Trust scale and the self-efficacy scales and analyzed using multiple linear regression. A convenience sample of 125 patients between the ages …

Predicting Pathologic ≥N2 Disease In Women With Breast Cancer, Kerollos Nashat Wanis, Wenli Dong, Yu Shen, Funda Meric-Bernstam, Taiwo Adesoye, Henry M Kuerer, Abigail S Caudle, Nina Tamirisa, Sarah M Desnyder, Susie X Sun, Isabelle Bedrosian, Puneet Singh, Solange E Cox, Kelly K Hunt, Rosa F Hwang

Faculty, Staff and Student Publications

The distinction between pN1 and ≥pN2 breast cancer impacts treatment decisions. Using data from a single institution on women with cN0 invasive breast cancer who were treated with upfront surgery, had 1-3 positive SLNs, and underwent completion ALND, we used gradient boosted trees (XGBoost) to develop a model for predicting ≥pN2 disease using clinicopathologic variables. Model performance was tested in a held-out subsample (20%) and validated using data from the National Cancer Database (NCDB). Of 3574 patients with cN0 breast cancer, 587 underwent upfront surgery and had 1-3 positive SLNs. Of these, 415 (70.7%) underwent completion ALND, with 64 (15.4%) …

It Is Not Clear How Well Physical Activity Promotion Materials Are Understood: Findings From A Rapid Literature Review, Jafra D. Thomas, Jasmine C. Wong, Regina F. Hockert, Yi Sheng Wu, Winston Kennedy

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 6: Issue 1, Article 6, 2025. Efforts to promote physical activity and other health-related behaviors are more effective when resource materials are understood by a wide and diverse audience. Before our lab’s previous investigations (Thomas et al., 2024), only one study seemed to use the cloze procedure to directly test the comprehension (i.e., readability) of physical activity promotion material (Cardinal & Seidler, 1995). Thus, this rapid literature review sought to (a) determine the extent the cloze procedure has been used to study physical activity promotion material comprehension in lay adults and (b) collate …

A Checklist Of Illinois Centipedes (Chilopoda), Gerald Summers, J. A. Beatty, Nanette Magnuson

The Great Lakes Entomologist

Records for 45 centipede species occurring in Illinois are given with a brief discussion of general habitat features and the effects of certain environmental factors on specific distribution patterns. The chilopod fauna of Illinois includes species from southeastern, western, and northern physiographic regions and represents a richer mixture of chilopod species than is found in any adjacent state.

Description And Biology Of Bumblebees (Hymenoptera: Apidae) In Michigan, Robert W. Husband, Roland L. Fischer, T. Wayne Porter

The Great Lakes Entomologist

The distribution of Michigan Bombinae was first studied by Milliron (1939). Records of Michigan bumblebees were included in Cockerell (1916) Franklin (1912). Lutz and Cockerell (1920). and Mitchell (1962). Other major studies in the Great Lakes Region were Chandler (1950) for Indiana, Medler and Carney (1%3) for Wisconsin, Husband (1966) for Michigan, Macfarlane (1974) for Ontario, LaBerge and Webb (1962) for Nebraska, Stevens (1948) for North Dakota, Frison (1926) for Illinois, and Neave (1933) for Manitoba. The purpose of this paper is to add to the information presented by Milliron (1939) and to complement the works by Chandler, Medler and …

The Biology Of The White Pine Sawfly, Neodiprion Pinetum (Hymenoptera: Diprionidae) In Wisconsin, Aunu Rauf, D. M. Benjamin

The Great Lakes Entomologist

The white pine sawfly, Neodiprion pirletunl. is monophagous on eastern white pine, Pinus strobus, throughout its range in eastern North America. Localized outbreaks occur frequently, and small areas of white pine may be killed. The high population upsurge in Crawford County. Wisconsin, in 1978 was mitigated by the eulophid egg parasite, Closterocerus cinctipennis, when a mean 90.1 t 4.870 parasitization occurred. Larval parasitization in the Grant County infestation averaged 45.05%. and involved the ichneumonid, Olesicampe lophyri, the perilampid Perilamplts l~yalirllcs, and the tachinid Spathimeigenia erecta.

Validation Of A Pete Timing Model For The Oriental Fruit Moth In Michigan And Central California (Lepidoptera: Olethreutidae), B. A. Croft, M. F. Michels, R. E. Rice

The Great Lakes Entomologist

PETE (Predictive Extension Timing Estimator) model output for Grapholitha molesta (Busck) was within ca. 30 ? 46 degree-days or 1.4 2 2 days of predicting 50% adult moth activity as measured by pheromone trap catches in the spring and first summer generation in both Michigan apple and California Peach orchards. In subsequent summer generations. model output was less reliable.

Instar Head Widths, Individual Biomass, And Development Rate Of Forest Tent Caterpillar, Malacosoma Disstria (Lepidoptera: Lasiocampidae), At Two Densities In The Laboratory, Jocelyn M. Muggli, William E. Miller

The Great Lakes Entomologist

Two colonies of forest tent caterpillar were reared at different densities on trembling aspen foliage in an environment chamber programmed for natural temperatures. Based on direct observation of molting, both colonies underwent five instars which overlapped negligibly in head width. Instar head widths were relatively stable between colonies, but individual biomass was sensitive to the different densities. Instars 3-5 in the less dense colony were heavier than those of the more dense by factors of 1.3-1.9. Development to 10-20% of larvae spinning cocoons took 40 days in the less dense colony and 45 days in the more dense. Size of …

Annotated List Of Trichoptera Collected Along Furnace Run Of The Cuyahoga Valley National Recreation Area In Northeastern Ohio, C. Peterson, B. A. Foote

The Great Lakes Entomologist

Information on seasonal distribution of 46 species of Trichoptera occurring along a small, unpolluted, woodland stream in northeastern Ohio is presented. Two species. Hydropsyclle hageni and Polycentroprcs interruptus, are newly recorded for the state.

Localized Field Migration Of The Adult Alfalfa Weevil, Clover Leaf Weevil, And Clover Root Curculio (Coleoptera: Curculionidae), And Its Implication For A Fall Pest Management Program, Robert D. Pausch, Stephen J. Roberts, Robert J. Barney, Edward J. Armbrust

The Great Lakes Entomologist

The migration of the alfalfa weevil, clover leaf weevil and clover root curculio from aestivation sites into adjacent alfalfa fields was monitored with several different trapping systems. It was found that the initial dispersal back into alfalfa fields following aestivation was a slow gradual movement across the soil surface with flight occurring only after the insects had been in the alfalfa for several days.

Observations On The Biology Of The Slender Seedcorn Beetle, Clivina Impressifrons (Coleoptera: Carabidae), Robert D. Pausch, Lois M. Pausch

The Great Lakes Entomologist

The slender seedcorn beetle, Clirina impressijirons, is known to attack germinating corn seed, but field and laboratory studies of its life history indicate it may sometimes play a beneficial role. Feeding studies show that adults and larvae are primarily carnivorous but will feed on corn seed when their primary food is absent or in short supply. Certain behavioral aspects indicate that populations of this beetle might be attracted to selected agricultural areas where adults and larvae could serve as predators of soil pests of corn. Much of the activity of these beetles is governed by temperature. with low temperatures below …

Mixed Species Feeding Assemblages Of Planthopper Nymphs (Homoptera: Fulgoroidea), S. W. Wilson, J. E. Mcpherson

The Great Lakes Entomologist

The occurrence of four species of southern Illinois fulgoroids in mixed species feeding assemblages is reported.

Seasonal Flight Patterns Of Hemiptera In A North Carolina Black Walnut Plantation. 1. Pentatomoidea, J. E. Mcpherson, B. C. Weber

The Great Lakes Entomologist

The seasonal flight patterns of 35 species and subspecies of Pentatomoidea collected in window traps in a North Carolina black walnut plantation are discussed. Flying height distributions and seasonal activities of the five species that were most frequently collected (i.e., Amnestus basidentatus, A. pallidus, A. spinifrons, Brochymena qltadripustulata and Euschistus servus) are considered in detail.

Getting The Most Out Of Your Maternity Leave, Joey Averett

Family Perspectives

No abstract provided.

Poverty In Association To Academic Achievement In Children, Sara Tolley

Family Perspectives

This paper explores the impact of poverty on academic achievement in children. It begins by outlining the general effects of poverty before delving into its specific consequences for educational outcomes. Findings indicate that poverty significantly affects self-esteem and family relationships, which, in turn, contribute to lower academic performance among children. Additionally, the paper proposes underlying causes for these outcomes and potential interventions. These insights are supported by a diverse range of data, highlighting the urgent need to address this critical issue.

The Relationship Between Immigration And Academic Achievement In Hispanic Children, Jasmine Selph

Family Perspectives

This literature review explores the relationship between immigration and academic achievement among Hispanic immigrant children in the United States, focusing on the impacts of immigration trauma and poverty. With immigration levels reaching record highs, Hispanic immigrant children face unique challenges that significantly influence their educational outcomes. Research highlights the profound effects of immigration trauma, including familial separation, violence, and insecurity, which manifest in physical, emotional, and cognitive difficulties that hinder academic performance. Additionally, poverty compounds these challenges, creating barriers to educational success through limited resources, language acquisition difficulties, and intergenerational cycles of disadvantage. The review also examines the roles of …

Suicidal Ideation Of Queer Adolescents, Haley Kamikawa

Family Perspectives

Suicide is the second leading cause of death in youth ages 15-29 around the world. This literature review examines some of the reasons why adolescents are likely to experience suicidal ideation and emphasizes why queer adolescence are at a much greater risk for suicidal ideation (Li Kitts, 2005; McDermott et al., 2018; Wichstrøm & Hegna, 2003). Bullying and lack of parental support were found to be the greatest contributors for queer adolescence experiencing suicidal ideation (Czyz et al., 2018; Sultana et al., 2023; Wedell, 2024). Bullying and lack of parental acceptance has been found to increase levels of emotional distress …