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1,882 full-text articles. Page 77 of 89.

Kyphotic Progression After Thoracolumbar Burst Fractures Treated Conservatively, With Mis, Or Via Open Approach, Mark Rivkin, Howard Eisenbrock 2014 Philadelphia College of Osteopathic Medicine

Kyphotic Progression After Thoracolumbar Burst Fractures Treated Conservatively, With Mis, Or Via Open Approach, Mark Rivkin, Howard Eisenbrock

Research Day

Management of thoracolumbar burst fractures (AO A3) without neurological deficit is subject to debate in the literature. While TLICS provides guidance for injuries necessitating intervention, it makes little mention of best surgical approaches. Furthermore, intact patients with suspected posterior ligamentous complex injury (TLICS 4) compose an additional level of management uncertainty. Present study examined outcomes for TL burst fractures in neurologically intact patients with suspected disruption of the PLC treated with bracing, MIS, or open fixation and fusion.


Fathoming Huntington’S Disease, Genetic Testing And The Biotechnological Era In An Academic Setting, Kenneth P. Serbin 2014 University of San Diego

Fathoming Huntington’S Disease, Genetic Testing And The Biotechnological Era In An Academic Setting, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


The Reversal Effects Of Curcumin, An Herbal Remedy, On The Impairments Induced By Vmat-2 Inhibitor Tetrabenazine, Emily Qian, Samantha E. Yohn 2014 University of Connecticut - Storrs

The Reversal Effects Of Curcumin, An Herbal Remedy, On The Impairments Induced By Vmat-2 Inhibitor Tetrabenazine, Emily Qian, Samantha E. Yohn

Honors Scholar Theses

Substantial evidence has shown that dopamine (DA), particularly in the nucleus accumbens (NAc), is involved in behavioral activation and effort-related processes, such as overcoming work related response costs. Interference with accumbens DA transmission through administration of the vesicular monoamine transportor-2 (VMAT-2) inhibitor tetrabenazine (TBZ) produces an alteration of response allocation in the concurrent FR5/chow choice procedure, biasing animals toward the lower effort alternative. It has been suggested that these drug-induced shifts in effort-related choice behavior seen in rodents are analogous to symptoms such as psychomotor retardation, anergia, and fatigue, which can be observed in people with depression and other related …


Visions Of Living With Parkinson's Disease: A Photovoice Study, Danice Greer, Cheryl Cooper, Melinda Hermanns 2014 The University of Texas at Tyler

Visions Of Living With Parkinson's Disease: A Photovoice Study, Danice Greer, Cheryl Cooper, Melinda Hermanns

Faculty Posters

This poster was presented at the May 2014 UT Tyler Faculty Awards.


Propagation Of Oligomeric Α-Synuclein And Amyloid-Β: Implications For Parkinson's And Alzheimer's Diseases, Matthew Stephen Planchard 2014 University of Southern Mississippi

Propagation Of Oligomeric Α-Synuclein And Amyloid-Β: Implications For Parkinson's And Alzheimer's Diseases, Matthew Stephen Planchard

Master's Theses

The aggregation of amyloidogenic proteins is a critical event in the pathology of a variety of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). The proteins α-synuclein (αS) and amyloid-β (Aβ) are involved in the formation of amyloid lesions observed in PD and AD, respectively. Both PD and AD exhibit a significant amount of co-pathology in clinical settings, and the αS and Aβ proteins have been shown to interact in vitro. Recent experimental consensus has shown oligomeric species to be significant, if not primary, sources of toxicity in these diseases. …


Epigenetic Remodeling In An Imr-32 Cell Line And Transgenic Mouse Model Of Alzheimer's Disease, Matthew S. Baker 2014 Liberty University

Epigenetic Remodeling In An Imr-32 Cell Line And Transgenic Mouse Model Of Alzheimer's Disease, Matthew S. Baker

Senior Honors Theses

The pathological features of Alzheimer’s disease (AD) have been researched and documented extensively, however the causes of these features are still unknown. The following studies sought to determine if epigenetic methylation alterations contribute to AD. Two studies were sequentially carried out, first using an IMR-32 model and then using a transgenic mouse model overexpressing beta-amyloid. A few assay and confirmation methods were carried out to determine the promoter regions in disease state models undergoing drastic change, and the genes linked to these promoter regions were analyzed to determine significant gene ontology being altered by this epigenetic modification. This data was …


After A Social Security Setback, Hdsa Steps Up Advocacy On Huntington's Disability Criteria, Kenneth P. Serbin 2014 University of San Diego

After A Social Security Setback, Hdsa Steps Up Advocacy On Huntington's Disability Criteria, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Woody Guthrie, Huntington’S Disease, And Our Duty To Improve Caregiving, Kenneth P. Serbin 2014 University of San Diego

Woody Guthrie, Huntington’S Disease, And Our Duty To Improve Caregiving, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Reshaping My Career And Life In The Face Of Huntington's Disease (And A Note Of Hope), Kenneth P. Serbin 2014 University of San Diego

Reshaping My Career And Life In The Face Of Huntington's Disease (And A Note Of Hope), Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Brain Blast 2014 Poster, Annie Leslie 2014 University of New England

Brain Blast 2014 Poster, Annie Leslie

Brain Blast

Announcement poster for UNE's Brain Blast 2014, a pechakucha-style brain health and safety awareness and learning event.


Brain Blast 2014 Speakers Poster, Annie Leslie 2014 University of New England

Brain Blast 2014 Speakers Poster, Annie Leslie

Brain Blast

Poster from UNE's Brain Blast 2014 listing the presenters at this event.


Health, Wellness, And The Pursuit Of Happiness: Common Ground For Adults With Cerebral Palsy And Modern Physical Therapists, Lisa Blumberg, Mary E. Gannotti, Diana J. LaRocco, Yvette Blanchard 2014 University of Hartford

Health, Wellness, And The Pursuit Of Happiness: Common Ground For Adults With Cerebral Palsy And Modern Physical Therapists, Lisa Blumberg, Mary E. Gannotti, Diana J. Larocco, Yvette Blanchard

Physical Therapy Faculty Publications

Health, wellness, and happiness are important long-term goals for adulthood, especially for children with cerebral palsy (CP). Physical therapists (PTs) can assist individuals with CP realize these goals; however it requires PTs to have a greater understanding of how to apply impairment, functional, or contextual interventions to meet these goals. A critical gap in knowledge exists about perceptions of happiness and health priorities of adults with CP. The purpose of this paper is to describe the beliefs, feelings, and perceptions of happiness and health of adults with CP as compared to adults without CP, specifically PTs.


What’S In A Name? How Huntington’S Disease Gene Carriers Are Seen By Themselves And Others, Kenneth P. Serbin 2014 University of San Diego

What’S In A Name? How Huntington’S Disease Gene Carriers Are Seen By Themselves And Others, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


‘It’S Really Getting Real’: Payoffs In The Effort To Treat Huntington's Disease, Kenneth P. Serbin 2014 University of San Diego

‘It’S Really Getting Real’: Payoffs In The Effort To Treat Huntington's Disease, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Accentuating The Positive: Olympic Medalist Sarah Winckless's Strategy Against Huntington's Disease, Kenneth P. Serbin 2014 University of San Diego

Accentuating The Positive: Olympic Medalist Sarah Winckless's Strategy Against Huntington's Disease, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Attention Deficit Associated With Early Life Interictal Spikes In A Rat Model Is Improved With Acth, Amanda E. Hernan, Abigail Alexander, Pierre-Pascal Lenck-Santini, Rod C. Scott 2014 Dartmouth College

Attention Deficit Associated With Early Life Interictal Spikes In A Rat Model Is Improved With Acth, Amanda E. Hernan, Abigail Alexander, Pierre-Pascal Lenck-Santini, Rod C. Scott

Dartmouth Scholarship

Children with epilepsy often present with pervasive cognitive and behavioral comorbidities including working memory impairments, attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder. These non-seizure characteristics are severely detrimental to overall quality of life. Some of these children, particularly those with epilepsies classified as Landau-Kleffner Syndrome or continuous spike and wave during sleep, have infrequent seizure activity but frequent focal epileptiform activity. This frequent epileptiform activity is thought to be detrimental to cognitive development; however, it is also possible that these IIS events initiate pathophysiological pathways in the developing brain that may be independently associated with cognitive deficits. These …


To Take, Or Not To Take, Unproven Supplements In The Fight Against Huntington's Disease, Kenneth P. Serbin 2014 University of San Diego

To Take, Or Not To Take, Unproven Supplements In The Fight Against Huntington's Disease, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Proof Of Heaven? My Ongoing Search For The Meaning Of Huntington's Disease In Life And Death, Kenneth P. Serbin 2014 University of San Diego

Proof Of Heaven? My Ongoing Search For The Meaning Of Huntington's Disease In Life And Death, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Riding The Advocacy Revolution: Stem Cell Activists. The Future Of Cirm, And Public Awareness, Kenneth P. Serbin 2014 University of San Diego

Riding The Advocacy Revolution: Stem Cell Activists. The Future Of Cirm, And Public Awareness, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Game-Changers In The Fight Against Disease: A Report From The World Cup Cell Summit, Kenneth P. Serbin 2014 University of San Diego

Game-Changers In The Fight Against Disease: A Report From The World Cup Cell Summit, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


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