Open Access. Powered by Scholars. Published by Universities.®

Cardiovascular Diseases Commons

Open Access. Powered by Scholars. Published by Universities.®

1,872 Full-Text Articles 5,606 Authors 368,554 Downloads 156 Institutions

All Articles in Cardiovascular Diseases

Faceted Search

1,872 full-text articles. Page 82 of 85.

Prevalence Of Thyroid Disorders Among Older People: Results From The São Paulo Ageing & Health Study, Paulo A. Lotufo 2011 Universidade de São Paulo

Prevalence Of Thyroid Disorders Among Older People: Results From The São Paulo Ageing & Health Study, Paulo A. Lotufo

Paulo A Lotufo

This study aimed to estimate prevalence of thyroid disorders in the São Paulo Ageing & Health Study, an epidemiological study addressing several health-adverse outcomes among elderly people living in a poor area of São Paulo, Brazil. All participants answered a questionnaire and had a blood sample collected to assess levels of tireotropic hormone and free-thyroxine. Among 1,373 people (60.8% women), prevalence rates (95% confidence interval) for thyroid dysfunction (%) were: overt hyperthyroidism, 0.7% (0.2-1.1) [women: 0.8% (0.2-1.5); men: 0.4% (0.01-0.9)]; overt hypothyroidism, 5.7% (4.5-6.9) [women: 5.9% (4.3-7.5); men: 5.4% (3.5-7.3)]; subclinical hyperthyroidism, 2.4% (1.6-3.2) [women: 2.8% (1.6-3.9); men: 1.9% (0.7-3.0)]; and subclinical hypothyroidism, 6.5% (5.2-7.8) [women: 6.7% (5.0- 8.4); men: 6.1% (4.1-8.2)]. There was no difference in prevalence rates according to gender, but almost 40% of women were diagnosed and under treatment compared ...


Detection Of Cardiac Myosin Heavy Chain-Α-Specific Cd4 Cells By Using Mhc Class Ii/IaK Tetramers In A/J Mice, Chandirasegara Massilamany, Arunakumar Gangaplara, Nora M. Chapman, Noel Rose, Jay Reddy 2011 University of Nebraska-Lincoln

Detection Of Cardiac Myosin Heavy Chain-Α-Specific Cd4 Cells By Using Mhc Class Ii/IaK Tetramers In A/J Mice, Chandirasegara Massilamany, Arunakumar Gangaplara, Nora M. Chapman, Noel Rose, Jay Reddy

Jay Reddy Publications

A/J mice bearing the H-2 allele IAk are highly susceptible to autoimmune myocarditis induced with cardiac myosin heavy chain (Myhc)-α 334–352, whereas B10.A mice carrying a similar allele IAk are relatively resistant, suggesting that the generation of Myhc-α-reactive T cell repertoires is influenced by genetic background. To enumerate the precursor frequencies of Myhc-α-specific CD4 T cells, we sought to create IAk tetramers for Myhc-α 334–352. Tetramers were created using approaches that involve covalent tethering of individual peptide sequences or exogenous loading of peptides into empty IAk molecules by peptide-exchange reaction. Using ribonuclease 43– 56 tetramers ...


Can Ultrafiltration Be Used As Primary Treatment Of Congestive Heart Failure?, Jennifer Tallis 2011 Philadelphia College of Osteopathic Medicine

Can Ultrafiltration Be Used As Primary Treatment Of Congestive Heart Failure?, Jennifer Tallis

PCOM Physician Assistant Studies Student Scholarship

Objective: To determine whether ultrafiltration can be used as primary treatment of Congestive Heart Failure.


Does Cardiac Resynchronization Therapy And Aerobic Exercise Improve Exercise Tolerance / Ability In Heart Failure Patiens Better Then Either Intervention Alone Or No Intervention At All?, Douglas Ader 2011 Philadelphia College of Osteopathic Medicine

Does Cardiac Resynchronization Therapy And Aerobic Exercise Improve Exercise Tolerance / Ability In Heart Failure Patiens Better Then Either Intervention Alone Or No Intervention At All?, Douglas Ader

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this systematic review is to determine whether or not cardiac resynchronization therapy with aerobic exercise improves exercise tolerance / ability better then either treatment alone or no intervention at all.


Is Vitamin E Supplementation Effective In Reducing Mortality Related To Cardiovascular Events In People With Type 2 Diabetes Mellitus?, Payal Amin 2011 Philadelphia College of Osteopathic Medicine

Is Vitamin E Supplementation Effective In Reducing Mortality Related To Cardiovascular Events In People With Type 2 Diabetes Mellitus?, Payal Amin

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this systematic review is to determine whether or not Vitamin E is effective in reducing the mortality related to cardiovascular event in patients with Type 2 Diabetes mellitus.


Transitions Home For Patients With Heart Failure: A Pilot Program At A Critical Access Hospital, Rita M. Willey Dr. 2011 University of Massachusetts Amherst

Transitions Home For Patients With Heart Failure: A Pilot Program At A Critical Access Hospital, Rita M. Willey Dr.

Doctor of Nursing Practice (DNP) Projects

Background: Heart Failure (HF) disease management programs (DMP) have shown to improve outcomes. The aim of this heart failure pilot program is an evaluation program. Measurement of functional capacity utilized the Duke Activity Status Index (DASI) questionnaire. Since the DASI uses the patient’s ability to perform a set of common activities of daily living to gauge functional capacity based on the known metabolic cost of each activity in MET units, it is thought to be well suited for population studies in which assessment of functional capacity during follow-up is needed.

Setting: Rural Critical Access Hospital (CAH) with outpatient cardiology ...


Association Between Depression And C-Reactive Protein, Yunsheng Ma, David E. Chiriboga, Sherry L. Pagoto, Milagros C. Rosal, Wenjun Li, Philip A. Merriam, James R. Hebert, Matthew Whited, Ira S. Ockene 2011 University of Massachusetts Medical School

Association Between Depression And C-Reactive Protein, Yunsheng Ma, David E. Chiriboga, Sherry L. Pagoto, Milagros C. Rosal, Wenjun Li, Philip A. Merriam, James R. Hebert, Matthew Whited, Ira S. Ockene

Preventive and Behavioral Medicine Publications

Objective: Depression has been associated with increased cardiovascular disease risk, and a depression–related elevation of high sensitivity C-reactive protein (hs-CRP) has been proposed as a possible mechanism. The objective of this study was to examine association between 27 depression and high sensitivity C-reactive protein (hs-CRP).

Methods: Subjects consisted of 508 healthy adults (mean age 48.5 years; 49% women, 88% white) residing in central Massachusetts. Data were collected at baseline and at quarterly intervals over a one-year period per individual. Multivariable linear mixed models were used to assess the association for the entire sample and by gender.

Results: The ...


Predictors Of Coronary Artery Visualization In Kawasaki Disease., Renee Margossian, Minmin Lu, L LuAnn Minich, Timothy J. Bradley, Meryl S. Cohen, Jennifer S. Li, Beth F. Printz, Girish S. Shirali, Lynn A. Sleeper, Jane W. Newburger, Steven D. Colan, Pediatric Heart Network Investigators 2011 Children's Mercy Hospital

Predictors Of Coronary Artery Visualization In Kawasaki Disease., Renee Margossian, Minmin Lu, L Luann Minich, Timothy J. Bradley, Meryl S. Cohen, Jennifer S. Li, Beth F. Printz, Girish S. Shirali, Lynn A. Sleeper, Jane W. Newburger, Steven D. Colan, Pediatric Heart Network Investigators

Manuscripts, Articles, Book Chapters and Other Papers

Background: Echocardiography is the imaging modality of choice for the evaluation of coronary artery (CA) abnormalities in Kawasaki disease. Small series have established high specificity and sensitivity for detecting abnormalities, yet visualization rates of individual CA segments and factors associated with success are unknown.

Methods: In the Pediatric Heart Network's randomized trial of primary steroid treatment for Kawasaki disease, echocardiograms were interpreted locally and by a core laboratory. Univariate and multivariate predictors of CA visualization by the local lab as determined by the core lab were explored, and agreement of CA size measured locally and by the core lab ...


A Prospective Study Of Positive Psychological Well-Being And Coronary Heart Disease, Julia K. Boehm, Christopher Peterson, Mika Kivimaki, Laura D. Kubzansky 2011 Chapman University

A Prospective Study Of Positive Psychological Well-Being And Coronary Heart Disease, Julia K. Boehm, Christopher Peterson, Mika Kivimaki, Laura D. Kubzansky

Psychology Faculty Articles and Research

Objective: Research suggests that positive psychological well-being is associated with cardiovascular health. However, much of this research uses elderly samples and has not determined the pathways by which psychological well-being influences cardiovascular disease or whether effects are similar for men and women. This study investigates the association between two aspects of well-being (emotional vitality and optimism) and coronary heart disease (CHD) in a sample of middle-aged men and women, and considers potential mediating factors.

Method: Between 1991 and 1994, well-being and coronary risk factors were assessed among 7,942 individuals without a prior cardiovascular event from the Whitehall II cohort ...


Development Of A Positive Psychology Intervention For Patients With Acute Cardiovascular Disease, Jeff C. Huffman, Carol A. Mastromauro, Julia K. Boehm, Rita Seabrook, Gregory L. Fricchione, John W. Denninger, Sonja Lyubomirsky 2011 Harvard Medical School

Development Of A Positive Psychology Intervention For Patients With Acute Cardiovascular Disease, Jeff C. Huffman, Carol A. Mastromauro, Julia K. Boehm, Rita Seabrook, Gregory L. Fricchione, John W. Denninger, Sonja Lyubomirsky

Psychology Faculty Articles and Research

The management of depression and other negative psychological states in cardiac patients has been a focus of multiple treatment trials, though such trials have not led to substantial improvements in cardiac outcomes. In contrast, there has been minimal focus on interventions to increase positive psychological states in cardiac patients, despite the fact that optimism and other positive states have been associated with superior cardiovascular outcomes. Our objective was to develop an 8-week, phone-based positive psychology intervention for patients hospitalized with acute cardiac disease (acute coronary syndrome or decompensated heart failure). Such an intervention would consist of positive psychology exercises adapted ...


Comparison Of Predictive Protocols In Chest Pain Patients In A Tertiary Care Hospital In Karachi, Pakistan, Omer Moin, Uzma Khan, Nadeem Ullah Khan, Munawar Khursheed, Junaid Razzak 2011 Aga Khan University

Comparison Of Predictive Protocols In Chest Pain Patients In A Tertiary Care Hospital In Karachi, Pakistan, Omer Moin, Uzma Khan, Nadeem Ullah Khan, Munawar Khursheed, Junaid Razzak

Department of Emergency Medicine

Background: The most challenging aspect in evaluation of a patient presenting with chest pain in the Emergency Department (ED) is diagnosis of acute cardiac ischemia (ACI). Various decisions aids have been developed to aid the ED physician in the diagnosis of chest pain. Three different predictive protocols – the Goldman protocol, ACI-TIPI, and the Troponin protocol are used in predicting the occurrence of ACI. None of these decision aids have been tested in the Pakistani population, where risk factors and prevalence of CAD are much different than what is seen in other regions of the world.Aims: The aim of this ...


Effects Of Calcium Supplementation On Cardiovascular Disease In Postmenopausal Women, Raizel Robinson 2011 Touro College

Effects Of Calcium Supplementation On Cardiovascular Disease In Postmenopausal Women, Raizel Robinson

The Science Journal of the Lander College of Arts and Sciences

The following is an excerpt from the introduction of the article: In the United States, 53% of the population use dietary supplements. Of the people using supplements, 43% use calcium and 37% use vitamin D. However, 63% of women older than 60 years of age reported using dietary supplements (Park et al., 2009). Calcium supplementation, without co-administered vitamin D, increases the risk of myocardial infarction and cardiovascularrelated diseases among postmenopausal women. On the contrary, calcium supplementation with accompanied vitamin D may not produce similar effects.


Alteplase: The Clot Buster, Mayer Goldberg 2011 Touro College

Alteplase: The Clot Buster, Mayer Goldberg

The Science Journal of the Lander College of Arts and Sciences

The following is an excerpt from the introduction of this article: The human body is defined by many complex and inconsistent characteristics. For example, the body forms blood clots in traumatic events, but blood clots are likewise associated with hazardous or fatal conditions. Platelets are small cells, derived from the precursor megakaryocytes, which are responsible for blood clotting to prevent bleeding from a ruptured blood vessel. Platelets fasten to each other and release a coagulation factor that solidifies around the ruptured area to prevent blood loss. A subordinate quantity of platelets can result in excessive bleeding. However, high platelet numbers ...


Is Thrombolytic Therapy Safe When Used To Treat Elderly Patients?, Daniel Yaeger 2011 Touro College

Is Thrombolytic Therapy Safe When Used To Treat Elderly Patients?, Daniel Yaeger

The Science Journal of the Lander College of Arts and Sciences

Recently, research has been conducted to determine if thrombolytic therapy works to dissolve clots and if it is a safe treatment option. The specific purpose of this study is to determine if thrombolytic therapy is safe for use in the elderly. This study was conducted by reviewing the relevant literature that has been published from the time that research began to test the usefulness of thrombolytic therapy. Numerous journals were examined to ensure impartiality and emerge with an unbiased conclusion. The journals were discovered using PubMed article finder, using Google as a search engine, and by scrutinizing relevant references found ...


The Cardiac Atlas Project--An Imaging Database For Computational Modeling And Statistical Atlases Of The Heart, Carissa G. Fonseca, Michael Backhaus, David A. Bluemke, Randall D. Britten, Jae Do Chung, Brett R. Cowan, Alan H. Kadish 2011 Touro College

The Cardiac Atlas Project--An Imaging Database For Computational Modeling And Statistical Atlases Of The Heart, Carissa G. Fonseca, Michael Backhaus, David A. Bluemke, Randall D. Britten, Jae Do Chung, Brett R. Cowan, Alan H. Kadish

Office of the President Publications and Research

MOTIVATION: Integrative mathematical and statistical models of cardiac anatomy and physiology can play a vital role in understanding cardiac disease phenotype and planning therapeutic strategies. However, the accuracy and predictive power of such models is dependent upon the breadth and depth of noninvasive imaging datasets. The Cardiac Atlas Project (CAP) has established a large-scale database of cardiac imaging examinations and associated clinical data in order to develop a shareable, web-accessible, structural and functional atlas of the normal and pathological heart for clinical, research and educational purposes. A goal of CAP is to facilitate collaborative statistical analysis of regional heart shape ...


Organized Outpatient Stroke Care, Gustavo Saposnik 2010 St Michael's Hospital, University of Toronto

Organized Outpatient Stroke Care, Gustavo Saposnik

Gustavo Saposnik

Background and Purpose—Organized inpatient stroke care decreases mortality and morbidity irrespective of patient age, stroke severity, or stroke subtype. Limited information is available on whether organized outpatient care models such as stroke prevention clinics (SPC) improve outcomes after a transient ischemic attack or ischemic stroke. We compared 1-year mortality and stroke readmission in patients with transient ischemic attack or ischemic stroke referred versus not referred to an SPC. Methods—This was a retrospective cohort study including 16 468 consecutive patients with ischemic stroke or transient ischemic attack who were seen in the emergency department or admitted to a hospital ...


Penumonia: Risk Factors And Outcomes After Stroke, Gustavo Saposnik 2010 St Michael's Hospital, University of Toronto

Penumonia: Risk Factors And Outcomes After Stroke, Gustavo Saposnik

Gustavo Saposnik

No abstract provided.


Vitamin B In Stroke Prevention: A Journey From Observational Studies To Rct's., Gustavo Saposnik 2010 St Michael's Hospital, University of Toronto

Vitamin B In Stroke Prevention: A Journey From Observational Studies To Rct's., Gustavo Saposnik

Gustavo Saposnik

No abstract provided.


Care And Outcomes In Patients With Ischemic Stroke With And Without Preexisting Dementia, Gustavo Saposnik 2010 St Michael's Hospital, University of Toronto

Care And Outcomes In Patients With Ischemic Stroke With And Without Preexisting Dementia, Gustavo Saposnik

Gustavo Saposnik

No abstract provided.


Rurality And Event-Free Survival In Patients With Heart Failure, Jia-Rong Wu, Debra K. Moser, Mary Kay Rayens, Marla J. De Jong, Misook L. Chung, Barbara Riegel, Terry A. Lennie 2010 University of Pennsylvania

Rurality And Event-Free Survival In Patients With Heart Failure, Jia-Rong Wu, Debra K. Moser, Mary Kay Rayens, Marla J. De Jong, Misook L. Chung, Barbara Riegel, Terry A. Lennie

School of Nursing Departmental Papers

Background

Evidence of health disparities between urban and rural populations usually favors urban dwellers. The impact of rurality on heart failure (HF) outcomes is unknown.

Objective

We compared event-free survival between HF patients living in urban and rural areas.

Methods

In this longitudinal study, 136 patients with HF (male, 70%; age, mean ± SD 61 ± 11 years; New York Heart Association class III/IV, 60%) were enrolled. Patients' emergency department visits for HF exacerbation and rehospitalization during follow-up were identified. Rural status was determined by rural-urban commuting area code. Survival analysis was used to determine the effect of rurality on outcomes ...


Digital Commons powered by bepress