Dietetics and Clinical Nutrition Commons^™

Attentional Bias, Inhibitory Control, And Food Reinforcement As Mechanisms Promoting Eating Behavior After Exercise, Kylie F. L. Mcfee

Theses and Dissertations--Nutrition and Food Systems

Background: Excess weight and obesity are serious health conditions characterized by modifiable and nonmodifiable risk factors. Exercise is a common method for achieving weight loss; however, results are not always achieved due to post-exercise compensatory behaviors. Increased energy intake (EI) is thought to be the main compensatory behavior hindering weight loss among overweight and obese adults. It is important to determine and understand the mechanisms behind energy compensation following exercise, as this will allow for the discovery of future interventions that may provide individuals with ways to improve exercise as a weight loss treatment.

Objective: To determine if a single …

Investigating The Effects Of Body Weight Fluctuations On Insulin Resistance In Adults: A Nhanes Study, Jessica Claire Burke

All Master's Theses

The aim of this study was to investigate the effects of a history of weight cycling on insulin resistance (IR) utilizing the 2015-2020 NHANES database. A value greater than 3.2 for homeostatic model assessment of insulin resistance (HOMA-IR) was used to define IR. No study to date has examined the weight cycling question since its application in the NHANES 2015-2016 cycle year. RESULTS 53% of the total 4100 participants reported weight cycling at least once and 33% of the total were classified as having IR. Prevalence of IR and obesity were highest amongst those who weight cycled 3 times or …

Gabra5 Plays A Sexually Dimorphic Role In Pomc Neuron Activity And Glucose Balance, Zhou Pei, Yang He, Jonathan C Bean, Yongjie Yang, Hailan Liu, Meng Yu, Kaifan Yu, Ilirjana Hyseni, Xing Cai, Hesong Liu, Na Qu, Longlong Tu, Kristine M Conde, Mengjie Wang, Yongxiang Li, Na Yin, Nan Zhang, Junying Han, Camille Hs Potts, Nikolas A Scarcelli, Zili Yan, Pingwen Xu, Qi Wu, Yanlin He, Yong Xu, Chunmei Wang

Children’s Nutrition Research Center Staff Publications

Pro-opiomelanocortin (POMC) neurons are important for the regulation of body weight and glucose balance. The inhibitory tone to POMC neurons is mediated primarily by the GABA receptors. However, the detailed mechanisms and functions of GABA receptors are not well understood. The α5 subunit of GABAA receptor, Gabra5, is reported to regulate feeding, and we found that Gabra5 is highly expressed in POMC neurons. To explore the function of Gabra5 in POMC neurons, we knocked down Gabra5 specifically from mature hypothalamic POMC neurons using the clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 strategy. This POMC-specific knock-down of Gabra5 did not affect …

Tissue-Specific Mechanisms Of Bile Acid Homeostasis And Activation Of Fxr-Fgf19 Signaling In Preterm And Term Neonatal Pigs, Caitlin Vonderohe, Greg Guthrie, Barbara Stoll, Shaji Chacko, Harry Dawson, Douglas G Burrin

Children’s Nutrition Research Center Staff Publications

The tissue-specific molecular mechanisms involved in perinatal liver and intestinal farnesoid X receptor (FXR)-fibroblast growth factor 19 (FGF19) signaling are poorly defined. Our aim was to establish how gestational age and feeding status affect bile acid synthesis pathway, bile acid pool size, ileal response to bile acid stimulation, genes involved in bile acid-FXR-FGF19 signaling and plasma FGF19 in neonatal pigs. Term (n = 23) and preterm (n = 33) pigs were born via cesarean section at 100% and 90% gestation, respectively. Plasma FGF19, hepatic bile acid and oxysterol profiles, and FXR target gene expression were assessed in pigs …

Maternal Feeding Styles And Child Appetitive Traits: Direction Of Effects In Hispanic Families With Low Incomes, Maria A Papaioannou, Nilda Micheli, Thomas G Power, Teresia M O'Connor, Jennifer Orlet Fisher, Sheryl O Hughes

Children’s Nutrition Research Center Staff Publications

Feeding styles of parents have been associated with dietary quality/intake and weight outcomes; however, much of the research to date has been cross sectional and the direction of influence unclear. This prospective longitudinal study evaluated the direction of effects between feeding styles and child appetitive traits over time in a sample of 129 Hispanic parent/child dyads that participated in a larger study. Data analyzed for the current study were collected when the children were 4-5 years old and again at ages 7-9 years. Parents (all mothers) reported on their feeding styles and children's appetitive traits using well-established questionnaires. Cross-lagged panel …

Validation Of The Family Health Behavior Scale For The Brazilian Population, Luiza Tweedie Preto, Camila H Scarpatto, Laura Lessa Gaudie Ley, Carolina Silveira, Margareth Rodrigues Salerno, Jennette Palcic Moreno, Stela Maris De Jezus Castro, Linda Booij, Rita Mattiello

Children’s Nutrition Research Center Staff Publications

Objective: To validate the Family Health Behavior Scale (FHBS) for Brazilian families.

Methods: The sample included 272 children aged 5 to 12 years old. Caregivers and their healthy answered the FHBS and questions about physical activity. In addition, anthropometric measurements of the children's weight and height were performed, as well as the bioimpedance exam. The scale was translated and the following validities were assessed: content (qualitative analysis and content validity index), construct (factor analysis) and concurrent validity (difference between domains and the total score with the categories of BMI, fat percentage and physical activity). Reliability (Cronbach's alpha, ceiling-floor effect, two-half …

Seasonality Of Children's Height And Weight And Their Contribution To Accelerated Summer Weight Gain, Jennette P Moreno, Salma Musaad, Hafza Dadabhoy, Tom Baranowski, Stephanie J Crowley, Debbe Thompson, Tzuan A Chen, Craig A Johnston

Children’s Nutrition Research Center Staff Publications

No abstract provided.

Associations Of Prenatal Phthalate Exposure With Neurobehavioral Outcomes In 45- And 75-Month-Old Infants, Jenna L N Sprowles, Kelsey L C Dzwilewski, Francheska M Merced-Nieves, Salma M A Musaad, Susan L Schantz, Sarah D Geiger

Children’s Nutrition Research Center Staff Publications

Phthalates are ubiquitous endocrine-disrupting chemicals, and research indicates that prenatal exposure to some phthalates may affect neurodevelopment. In a prospective birth cohort study, five first-morning urine samples collected across pregnancy were pooled and the following phthalate biomarkers assessed: sum of di-(2-ethylhexyl) phthalate metabolites (ΣDEHP), sum of diisononyl phthalate metabolites (ΣDINP), sum of dibutyl phthalate metabolites (ΣDBP), sum of anti-androgenic metabolites (ΣAA), monoethyl phthalate (MEP), and sum of all phthalate metabolites (ΣAll). The Ages & Stages Questionnaires® (ASQ), a standardized parent-reported, age-adapted screening tool, measured communication, personal-social, problem solving, and motor domains in infants at 4.5 and 7.5 months (n = …

Depletion And Enrichment Of Phytosterols In Soybean Oil Lipid Emulsions Directly Associate With Serum Markers Of Cholestasis In Preterm Parenteral Nutrition-Fed Pigs, Greg Guthrie, Barbara Stoll, Shaji Chacko, Mahmoud Mohammad, Candace Style, Mariatu Verla, Oluyinka Olutoye, Deborah Schady, Charlotte Lauridsen, Nick Tataryn, Douglas Burrin

Children’s Nutrition Research Center Staff Publications

Background: Clinical reports show a positive correlation between phytosterol concentrations and severity of cholestatic liver disease markers in infants during long-term administration of parenteral lipid emulsions. Establishing a causal link between phytosterols and cholestasis has been complicated by confounding factors of lipid emulsion load, fatty acid composition, and vitamin E in many of these studies. The goal of this study is to determine whether altering the phytosterol concentration within a common soybean oil-based emulsion will alter the onset and severity of cholestasis in parenterally fed preterm piglets.

Methods: Preterm piglets were administered, for 21 days, either enteral nutrition (ENT) or …

How Do Low-Income Single-Mothers Get By When Unemployment Strikes: Patterns Of Multiple Program Participation After Transition From Employment To Unemployment, Chi-Fang Wu, Yu-Ling Chang, Soohyun Yoon, Salma Musaad

Children’s Nutrition Research Center Staff Publications

Little is known about longitudinal patterns of welfare program participation among single mothers after they transition from employment to unemployment. To better understand how utilization patterns of these welfare programs may change during the 12 months after a job loss, we used the 2008 Survey of Income and Program Participation to examine the patterns of participation in Medicaid, the Supplemental Nutrition Assistance Program, Temporary Assistance for Needy Families, and unemployment insurance among 342 single mothers who transitioned from employment to unemployment during the Great Recession. Using sequence analysis and cluster analysis, this paper identified four distinct patterns of program participation: …

New Natural Compound Inhibitors Of Pdgfra (Platelet-Derived Growth Factor Receptor Α) Based On Computational Study For High-Grade Glioma Therapy, Wenzhuo Yang, Shengnan Wang, Xiangmao Zhang, Hu Sun, Menghan Zhang, Hongyu Chen, Junxiang Cui, Jinyang Li, Fei Peng, Mingqin Zhu, Bingcheng Yu, Yifan Li, Liu Yang, Wanwan Min, Mengru Xue, Lin Pan, Hao Zhu, Bo Wu, Yinghao Gu

Children’s Nutrition Research Center Staff Publications

Background: High-grade glioma (HGG) is a malignant brain tumor that is common and aggressive in children and adults. In the current medical paradigm, surgery and radiotherapy are the standard treatments for HGG patients. Despite this, the overall prognosis is still very bleak. Studies have shown that platelet-derived growth factor receptor α (PDGFRA) is an essential target to treat tumors and inhibiting the activity of PDGFRA can improve the prognosis of HGG. Thus, PDGFRA inhibitors are critical to developing drugs and cancer treatment.

Objective: The purpose of this study was to screen lead compounds and candidate drugs with potential inhibitors against …

Bibliometric And Visual Analysis Of Research On The Links Between The Gut Microbiota And Pain From 2002 To 2021, Menghan Mao, Yanyu Zhou, Yingfu Jiao, Suqing Yin, Chiwai Cheung, Weifeng Yu, Po Gao, Liqun Yang

Children’s Nutrition Research Center Staff Publications

Background and aims: The gut microbiota is involved in the regulation of pain, which is proved by plenty of evidence. Although a substantial quantity of research on the link between the gut microbiota and pain has emerged, no study has focused on the bibliometric analysis of this topic. We aim to present a bibliometric review of publications over the past 20 years and predict research hot spots.

Methods: Relevant publications between 2002 and 2021 were extracted from the Science Citation Index-Expanded (SCI-EXPANDED) of the Web of Science Core Collection (WoSCC) database on April 22, 2022. CiteSpace (version 5.8 R3c), VOSviewer, …

Developing And Predicting Of Early Mortality After Endovascular Thrombectomy In Patients With Acute Ischemic Stroke, Yimin Chen, Sijie Zhou, Shuiquan Yang, Mohammad Mofatteh, Yuqian Hu, Hongquan Wei, Yuzheng Lai, Zhiyi Zeng, Yajie Yang, Junlin Yu, Juanmei Chen, Xi Sun, Wenlong Wei, Thanh N Nguyen, José Fidel Baizabal-Carvallo, Xuxing Liao

Children’s Nutrition Research Center Staff Publications

Background: Stroke is one of the leading causes of mortality across the world. However, there is a paucity of information regarding mortality rates and associated risk factors in patients with acute ischemic stroke (AIS) undergoing endovascular thrombectomy (EVT). In this study, we aimed to clarify these issues and analyzed previous publications related to mortality in patients treated with EVT.

Methods: We analyzed the survival of 245 consecutive patients treated with mechanical thrombectomy for AIS for which mortality information was obtained. Early mortality was defined as death occurring during hospitalization after EVT or within 7 days following hospital discharge from the …

Childhood Food Insecurity: A Program Impact And Evaluation Study Of The Meals On Wheels For Kids Program, Claudia Rivero

UNF Graduate Theses and Dissertations

In America, millions of families and children face hunger and food insecurity every day. According to the United States Department of Agriculture, more than thirty-eight million people experienced hunger in 2020. As many as 13 million children in the United States live in food-insecure homes. Many households that experience food insecurity do not qualify for federal nutrition programs. While valuable, barriers to these programs can block food-insecure households with children and prevent access to healthy food. The impact of adverse health and nutritional consequences, of a food-insecure household, will continue to plague our communities until efficient programming connects to those …

Exploring The Health Outcomes And Patient’S Viewpoint Of Pediatric Patients Receiving Medical Nutrition Therapy Visits With In-Person, Telephonic, And Tele-Video Modalities At A Rural Community Health Center, Valerie L. Muehleman

UNF Graduate Theses and Dissertations

The Covid-19 pandemic advanced telephonic (TP) and tele-video (TV) visits for medical nutrition therapy (MNT). This study explored the health outcomes and patient’s viewpoints of MNT by modalities in a community health center (CHC). Participants ranged in age from 1-18 years, diagnosed with overweight/obesity, and received MNT from a registered dietitian nutritionist (RDN) from January 1, 2019 to August 31, 2021. Health outcomes measured were health goal achievement, BMI percentile, pre/post lipid panel, and A1C%. Show/no-show rates and demographic characteristics of gender, age, race, insurance, county, language, and ethnicity were also compared by the visit modality. Ten interviews in the …

The Effects Of Fermented Vegetables On The Gut Microbiota For Prevention Of Cardiovascular Disease, Melissa Baron

UNF Graduate Theses and Dissertations

This study investigated the impact of regular consumption of fermented vegetables on markers of inflammation and the composition of the gut microbiota in adults at increased risk for cardiovascular disease. Eighty-seven adults ages 35-64 were randomized into a Fermented Vegetable (FV) (100g fermented vegetables daily at least 5x/wk), or a Usual Diet (UD) group. Blood and stool samples were obtained before and after the intervention for measurement of C-Reactive Protein, interleukin-6, angiopoietin-like protein 4, trimethylamine oxide, and lipopolysaccharide binding protein. Next-generation sequencing of the V4 region of the 16S rRNA gene isolated from stool samples was performed on the Illumina …

Nutrition Perception, Dietary Intake, And Anthropometric Correlations Between Autism Spectrum Disorder And Typically Developing Adolescents., Kristin M. Berg

UNF Graduate Theses and Dissertations

The adolescent’s nutrition perception is reflected in dietary intake and body composition. Obesity is prevalent among adolescents with Autism Spectrum Disorder (ASD). Dietary habits of children with ASD are affected by sensory issues, gastrointestinal factors, and parental provision of diet. This cross-sectional study identifies the relationships among variables for dietary intake, nutrition perception of intake, and anthropometric measurements for adiposity for 19 adolescents, ages 11 to 17, with ASD. Twenty-four children who are typically developing (TD) were assessed to compare all variables for significant differences. Measurements of variables of interest were obtained from the adolescent subjects: a 24-hour recall of …

Virtual Supervised Practice During The Covid-19 Pandemic. Does Virtual Learning Affect The Quality Of Preparation For The Rd Exam Or Beginning Dietetics Practice?, Shaynee M. Roper

UNF Graduate Theses and Dissertations

The Covid-19 pandemic has seemingly altered the practice of Dietetics, and its essential supervised practice component of the Dietetic Internship programs. Telehealth, in particular telenutrition, became a necessity of practice for the entire United States and many parts of the world. Medicare and many private insurance companies amended policies for the expansion, inclusion, and provision of MNT via telephone.¹ In addition, numerous Dietetic Interns were forced to complete the supervised practice (SPE) components of ACEND (Accreditation Council for Education in Nutrition and Dietetics) accredited programs virtually. The practice of telehealth is not a new concept. Indeed, this area of …

A Two-Day Virtual Workshop On The Micronutrient-Directed Nutrition-Focused Physical Exam For Ghanaian Nutrition Professionals: Examining Perceived Self-Efficacy And Innovation, Leah Anne Qubty

UNF Graduate Theses and Dissertations

Micronutrients are key components of various physiological processes. Therefore, in the setting of deficiency, poor health outcomes ensue. In Ghana, micronutrient deficiencies are common and medical resources are limited. The Ghanaian dietetics profession is growing, and this growth is propitiously timed to address micronutrient deficiencies. Biochemical markers of nutrition status are considered the gold standard to detect micronutrient deficiencies, but are costly and require specialized medical equipment. In the absence of available biochemical markers of nutrition status, the micronutrient-directed nutrition-focused physical exam is a viable tool. Nutrition professionals such as Registered Dietitians are qualified to conduct this exam, but feel …

The Effects Of Caffeine On Health And Perceived Bitterness, Chyann Farlin

Williams Honors College, Honors Research Projects

Caffeine is commonly consumed throughout the world in items such as coffee, chocolate, tea, energy drinks, and carbonated soft drinks. Consumers and food manufacturers benefit from discussion surrounding caffeine because consumers use information to drive their purchases. The purpose of this paper is to describe how caffeine effects health and perceived bitterness, and the ways that the food industry modifies bitter tastes in caffeine-containing products. Moderate caffeine intake is defined as 240-400 mg/day. Moderate intake of caffeine is not correlated to increased risk of premature death caused by disease or cancer. Excessive intake (>400mg/day) is neither protective nor harmful …