Community College Leadership Commons^™

The Role Of Integrin-Associated Protein “Pinch” In Kidney Development, Tyrone Gamble Jr, Roy Zent, Phd, Bertha C. Elias, Phd

Journal of Health Disparities Research and Practice

PINCH (a particularly interesting new cysteine-histidine-rich protein) is a protein that binds with Integrin-linked kinase and Parvin, to form an IPP complex. This complex is formed only when integrin molecules are activated upon interaction with the basement membrane. The IPP complex then acts as a platform for other proteins to come together and regulate cell signaling to and from the extracellular matrix (ECM). This allows for various cellular activities to progress like cell adhesion, migration, proliferation, etc. There are two types of PINCH proteins, PINCH-1 and PINCH-2. Studies from our group have shown that the lack of PINCH-1 in the …

Nitric Oxide And Cyclic Gmp Signaling In Cancer Therapy, Armond Dorsey, Ferid Murad, Md, Phd, Ka Bian, Md, Phd

Journal of Health Disparities Research and Practice

The nitric oxide-3’,5’-cyclic guanosine monophosphate signaling pathway (NO-cGMP signaling pathway) is a well-known signal transduction pathway which elicits several physiological processes including: cell proliferation, vasodilation, cardiac protection, etc. In this pathway, NO binds to the ferrous heme of histidine-105 on the prosthetic heme of the β₁ subunit of soluble guanylyl cyclase, resulting in the production of cGMP. This pathway, however, is inhibited in certain cancer cells—as observed in glioma cell lines. As a result, the production of cGMP is reduced. This mechanism may facilitate uncontrolled tumor cell growth.

The cancers under research—lung carcinoma, glioma, and pancreatic carcinoma—are all highly …

Potential Cost Savings Of Not Doing Cd4 Counts In Hiv Positive People In Rhode Island With An Undetectable Viral Load, Ruth Dele-Oni, Ferdinand Schumacher, Zachary Markus, Timothy Flanigan, Md

Journal of Health Disparities Research and Practice

CD4 cells fight infections in the body. When someone contacts Human Immunodeficiency Virus (HIV), their CD4 cells are taken over by HIV which turns them into manufacturers of many copies of the virus. The Viral Load (VL) measures the amount of virus in the blood. When HIV takes over the CD4 cells, the VL increases while the number of necessary CD4 cells decreases. When patients maintain stable treatment, their CD4 counts rise, and VLs may become undetectable, indicating the virus is too little to be detected in their blood. Knowing this, is frequent CD4 counts necessary for those with undetectable …

Defining The Role For Zbp-89 In Atm-Mediated Dna Damage Response To Irradiation In The Intestine, Christine Carethers, Juanita L. Merchant, Md, Phd

Journal of Health Disparities Research and Practice

ZBP-89 (ZNF148, Zfp148) is a zinc-finger transcription factor that inhibits cellular proliferation when overexpressed in cell lines. ZBP-89 forms a protein-protein interaction with p53 and Ataxia-telangiectasia mutated (ATM). However, it is unclear how the interaction modulates the function of these two proteins in vivo.

Double strand DNA breakage induced by -irradiation induces ATM phosphoinositol kinase activity, which initiates a cascade of events culminating in cell cycle arrest, DNA repair or apoptosis. Elevated levels of ZBP-89 induce growth arrest and apoptosis in gastrointestinal cell lines. Therefore, we hypothesize that ZBP-89 facilitates cell growth arrest and activation of the DNA repair pathway …

Induction Of Dusp9 In Xenografts From Human Breast Cancer Cell Lines Increases Mammary Cancer Stem Cells, Albert Barrios, Meher Parveen, Phd, Easter Thames, Melanie Baker, Shelha Pervin, Phd

Journal of Health Disparities Research and Practice

Breast cancer remains a complex disease that kills 40,000 women every year. Initiation and progression of breast cancer is influenced by heterogeneous groups of cells, including mammary cancer stem cells (MCSCs). Progression of this dreadful disease is driven by many signaling pathways among which MAPK pathway is highly prominent. Since targeting prominent kinases in MAPK pathway has been unsuccessful to control breast cancer, it is important to examine the phosphatases that regulate the activity of these kinases.

Using xenograft model from breast cancer cell lines, our lab has found that during the initial stages of xenograft development (week 1-4, 100-200mg …

Preparing Underrepresented High School Students To Increase Diversity In The Research And Health Professions, Dolores E. Caffey-Fleming, Ms, Mph, Christopher Reid, Md, Phd

Journal of Health Disparities Research and Practice

This article introduces the work that was done through the Coordinating Center at Charles R. Drew University of Medicine and Science.

The Step Up Program, Lawrence Agodoa, Md

Journal of Health Disparities Research and Practice

The Short-Term Research Experience Program for Underrepresented Persons (STEP-UP) was established as part of the NIDDK Strategic Plan on Minority Health Disparities. This article provides an overview and introduction of this program. All of the articles that are included in this special issue reflect the work of our coordinating centers, the mentors and their staff, as well as the students.

Implementation Of State Developmental Education Policy: A Multiple Case Study Of Community College Faculty Perceptions Of Involvement, Shirley Davenport

Department of Educational Administration: Dissertations, Theses, and Student Research

Numerous studies have indicated that developmental education as it is currently offered in many colleges and universities produces dismal results, with student success rates averaging as low as 25%. To address this issue, legislators in some states have begun to intervene, adopting policies that vary from suggestions for improvements to mandated pedagogical approaches. However, given the higher education organizational environment, the manner in which any change is implemented can be key to its success.

The purpose of this comparative multiple case study was to describe and interpret the perceptions of developmental education faculty regarding their level of involvement in developmental …

Relationship Between Mathematical And Radiation Science Scores To Graduation Success With Southwest Virginia Community College Radiography, Donna Corns

OTS Master's Level Projects & Papers

A well trained radiographer is necessary in hospital settings, clinics and physician’s offices. It is necessary for radiologic technologists to have mathematical skills, to possess knowledge of radiation science, to graduate from an accredited radiology program and to pass the national registry certification examination given by the American Registry of Radiologic Technologists. When looking at the attributes necessary for these individuals, a problem was determined. The problem of this study was to see if there is a correlation between grades of radiography students in mathematics and radiation science as predictors of program completion. To guide this study the following hypothesis …

Cultural Influences Of Resource Dependence: Community College Administrator Perceptions Of Implementing Initiatives Related To Tennessee’S Performance Funding Model, John Owen Driskill

Electronic Theses and Dissertations

The purpose of this phenomenological research study was to describe the cultural influences of resource dependence for community college administrators responsible for the implementation of initiatives related to Tennessee’s new performance funding program. Tennessee’s funding formula, considered one of the most aggressive and robust in the country, is among a second generation of performance funding programs commonly referred to as performance funding 2.0. Cultural influences of resource dependence were defined as values, beliefs, and customs that influence administrator efforts to improve institutional outcomes and acquire additional resources through performance funding.

A top performing community college in terms of the performance …

How Adjunct Faculty At Community Colleges Describe Their Sustained Motivation To Teach, Maureen E. Sheridan

Publications and Research

There is mounting concern over the influence that hiring larger percentages of adjunct faculty has had on the quality of instruction delivered in higher education. Studies have noted these contingent workers are being hired as an economic resource or commodity rather than viewed as academic partners. This basic inductive study on adjunct faculty in northeast U.S. two-year colleges was important to add to the existing body of knowledge. Utilizing a basic inductive approach allowed the researcher to explore adjunct faculty experiences and to gather data through individualized, semi-structured interviews. Data analysis was examined through the lens of hygiene-motivation theory that …

An Examination Of The Relationships Between Safety Culture Perceptions And Safety Reporting Behavior Among Non-Flight Collegiate Aviation Majors, Daniel Kwasi Adjekum, Julius Keller, Micah Walala, Cody Christensen, Randal J. Demik, John P. Young, Gary J. Northam

International Journal of Aviation, Aeronautics, and Aerospace

Some collegiate aviation programs in the United States have adopted the voluntary Safety Management System (SMS) strongly advocated by the Federal Aviation Administration to build a proactive safety culture. While relevant safety culture research has primarily focused on flight personnel, there has been limited investigation on non-flight collegiate aviation majors (collegiate air traffic control, aviation management, and unmanned aerial systems students) perceptions on collegiate aviation safety. This study examined the relationship between safety culture perceptions and safety reporting behavior of non-flight major students at five collegiate aviation programs. One hundred and sixteen completed responses to a validated safety culture perception …

Two-Year College Faculty Perspectives On Developmental Student Persistence: A Case Study, Mary Colleen Patterson

All Theses And Dissertations

This study sought to understand the perspectives of two-year college composition faculty concerning the persistence of students in their developmental composition courses. Research has shown that developmental students are a population at risk for leaving college before completing their degree programs and that students are more likely to persist to reach their goals when they’ve built meaningful connections with faculty. Many factors affect faculty ability to connect with developmental students such as faculty history, teaching preparation, and work load.

This study answered four research questions: 1) how do faculty describe and perceive their experience in encouraging developmental students to persist? …

An Examination Of The Relationships Between Safety Culture Perceptions And Safety Reporting Behavior Among Non-Flight Collegiate Aviation Majors, Daniel Kwasi Adjekum, Julius Keller, Micah Walala, Cody Christensen, Randal J. Demik, John P. Young, Gary J. Northam

Aviation Faculty Publications

Some collegiate aviation programs in the United States have adopted the voluntary Safety Management System (SMS) strongly advocated by the Federal Aviation Administration to build a proactive safety culture. While relevant safety culture research has primarily focused on flight personnel, there has been limited investigation on non-flight collegiate aviation majors (collegiate air traffic control, aviation management, and unmanned aerial systems students) perceptions on collegiate aviation safety. This study examined the relationship between safety culture perceptions and safety reporting behavior of non-flight major students at five collegiate aviation programs. One hundred and sixteen completed responses to a validated safety culture perception …

Impacts Of Open Educational Resources On Enrollment Rates, Withdrawal Rates, And Academic Performance In The Virginia Community College System, Marcella Milhous Gale

OTS Master's Level Projects & Papers

The problem of this study was to evaluate the enrollment rates and academic performance of students in courses at Central Virginia Community College (CVCC) that utilize Open Educational Resources (OER) to help determine if the use of such materials should be encouraged and expanded in the Virginia Community College System. The population for this study consisted of students enrolled in at least one course at CVCC during the Fall 2015 and Spring 2016 semester, where there were courses that used OER as the course textbook. At the end of each semester, CVCC records enrollment, drop, and academic performance information for …

Ethical Leadership In Today's Community Colleges: Presidents Respond To The Completion Agenda, Monica Parish Trent

Educational Leadership & Workforce Development Theses & Dissertations

The role of ethical leadership for community college presidents is of concern (Anderson, Harbour, & Davies; Wood & Nevarez, 2014), especially given the added pressure on community colleges to increase completion rates for student populations that have historically underperformed academically. In these times of increased scrutiny to produce more college-educated people ready to enter the workforce, college CEO’s are facing a completion agenda climate that is rampant with financial constraints, greater demands from stakeholders, and governmental mandates. The purpose of this descriptive, multiple case study was to examine how community college presidents execute ethical leadership in responding to institutional policy …

Establishing Community In Online Courses: A Literature Review, Amy J. Pilcher

College Student Affairs Leadership

The purpose of this literature review is to examine the evolution of online learning over the last several decades in relation to student engagement. Much has been made of both the successes and failures of online learning and, consequently, much has been written to enumerate the reasons for those successes and failures. After lengthy review, a great deal of the writing indicates that the relative success or failure of a student is caused by a confluence of three factors: the student, the environment, and the faculty. Online learning is unique in that a much greater share of the burden of …

Delivering Disability Accommodations At A Community College: A Case Study, Caolfionn B. Yenney, Janie Sacco Ii

College Student Affairs Leadership

This case study explores the Office of Disability Support Services (DSS) at Northern Midwestern Community College (NMCC). Like many state institutions of higher education, NMCC has undergone continued budgetary cuts, some of which have impacted their services. Additionally, NMCC faces limited support from administration and resistance from instructors to provide accommodations. Taking the position of the accommodations coordinator, this case study challenges readers to consider a student concern from an institutional, collaborative, student response, and strategic perspective.

Black Lives Matter, But Not Here: A Case Study, Jason R. Goode, Z Nicolazzo

College Student Affairs Leadership

Recently, the United States has experienced a wave of social movements that include protests and digital social justice movements through Facebook and Twitter. These movements have been sparked as a response to systematic racism within the university landscape and the police force. This case study looks into systematic racism at a large public university college campus. The setting is in a college town on a city street that connects the city jail to the campus. Readers will be introduced to several characters that are important to the story before reading an account of the tug of war treatment of Black …

Editor’S Corner: Strengthening Perspective By Exploring Complex Cases, Outcomes, And Literature, Lauren Presutti

College Student Affairs Leadership

Note from the editor-in-chief.