Other Medicine and Health Sciences Commons^™

Development Of A Programmable, Open-Source, And Cost-Effective Fluidic System For Cell Culture Applications, Charles Montoya

Biomedical Engineering ETDs

Open-source laboratory equipment has become an increasingly popular alternative to commercially available options due to its simple implementation, capability of user-customized modifications, and cost-effectiveness. Presented here is the development of a programmable and open-source fluidic system comprised of three custom-built syringe pumps for cell culture applications. The fluidic system was directly integrated with a multiwell plate on an environmentally controlled microscope platform for live-cell imaging and time-lapse analyses of cellular responses as culture conditions are adjusted using the programmable fluidic system. Proof-of-concept of this system is obtained by controlling autophagic activity in A549 cells by adjustment of nutrient supply. The …

Pharmacists Role In Preventing Drug Abuse, Renae L. Wilson

College of Pharmacy Student Research

In 2019, there were approximately 332,000 pharmacists active in the US workforce, Data USA, 2019. A survey of 1,700 American adults, discovered, that 34% of Americans still rely on healthcare providers such as pharmacists, for information in relation their health, KRC Research, 2018. Pharmacists are one of the three most trusted health care professions and were found to be the second most trusted source for health information by Americans in 2005. Blendon et al., 2006 found, that information from pharmacist was trusted by 67%, of participants in their survey. One of the oaths pledged by pharmacist is, ‘ …

Evaluation Of Residual Antibacterial Effects On Canine Skin Surface And Hairs Following Treatment With Five Commercial Mousse Products Against Staphylococcus Pseudintermedius In Vitro, Chi-Yen Wu

LSU Master's Theses

Topical products are essential treatments for canine superficial bacterial folliculitis. However, studies for commercial products typically evaluate antibacterial effects on hairs rather than the skin surface. In addition, the interference from the hair length has not been evaluated in these studies. Therefore, the study objective for this study was to evaluate the residual antibacterial effects of five mousse products, (1) 2% chlorhexidine and 2% miconazole, (2) 0.05% phytosphingosine, (3) 2% salicylic acid and 10% ethyl lactate, (4) 3% chlorhexidine and 0.5% climbazole, and (5) 2% chlorhexidine and 1% ketoconazole on both the skin surface and hairs in both short- and …

A Comparative Study On Deep Learning Models For Text Classification Of Unstructured Medical Notes With Various Levels Of Class Imbalance, Hongxia Lu, Louis Ehwerhemuepha, Cyril Rakovski

Mathematics, Physics, and Computer Science Faculty Articles and Research

Background

Discharge medical notes written by physicians contain important information about the health condition of patients. Many deep learning algorithms have been successfully applied to extract important information from unstructured medical notes data that can entail subsequent actionable results in the medical domain. This study aims to explore the model performance of various deep learning algorithms in text classification tasks on medical notes with respect to different disease class imbalance scenarios.

Methods

In this study, we employed seven artificial intelligence models, a CNN (Convolutional Neural Network), a Transformer encoder, a pretrained BERT (Bidirectional Encoder Representations from Transformers), and four typical …

Alumni Journal - Volume 93, Number 2, Loma Linda University School Of Medicine

Alumni Journal, School of Medicine

Editorials
2 | From the Editor
4| From the President
6 | From the Dean

News
8 | School of Medicine News
10 | Alumni News
11 | This and That
12 | Students
14 | AIMS Report
16 | Department Report: Gynecology and Obstetrics

Graduation 2022
19 | Graduation Feature

Features
34 | By the Graduates
38 | Graduate Medical Education at LLUH
42 | Curriculum Transformation
46 | Historical Snapshot
47 | Alumni Spotlight

In Memoriam
49 | Alumni Remembered: Featured obituaries - George T. Harding IV '53-B; John W. Mace '64

Effect Of Injury Mechanism And Severity On The Molecular Pathophysiology Of Traumatic Brain Injury, Brandon Mcdonald

Department of Biological Systems Engineering: Dissertations, Theses, and Student Research

Traumatic brain injury (TBI) mechanism and severity are heterogenous clinically, resulting in a multitude of physical, cognitive, and behavioral deficits. However, approximately 80% suffer from milder injuries. Thus, examining pathophysiological changes associated with mild TBI is imperative for improving clinical translation and evaluating the efficacy of potential therapeutic strategies. Through this work, we developed models of TBI, ranging in both injury mechanism and severity, using an electromagnetic controlled cortical impact (CCI) device. First, we characterized and optimized a closed head, mild TBI model (DTBI) to determine the clinical translatability and practicality of producing repeated mild injuries. Interestingly, we determined that …

Describing Healthcare Concerns Of Young People And Adults With Cerebral Palsy, Christina M. Winger

Electronic Thesis and Dissertation Repository

The purpose of this study was to identify healthcare concerns of young people and adults with cerebral palsy (CP) in the Transitional and Lifelong Care (TLC) program, and determine whether there were patient factors associated with the number of healthcare concerns. A retrospective chart review of initial TLC consultations was completed (n = 241). Descriptive and inferential statistics were used to explore and explain patterns in the sample population. The participants reported a high number of concerns of varied nature that were not easily predicted by condition-specific or demographic variables. This study may better healthcare delivery for young people …

Language-Based Strategies That Support Person-Centered Communication In Formal Home Care Interactions With Persons Living With Dementia, Reanne G. Mundadan

Electronic Thesis and Dissertation Repository

Background. Several studies recommend language-based strategies for communication with persons living with dementia. Language-based strategies improve coherence, clarity, reciprocity, and continuity of interactions. Person-centered communication (PCC) strategies are the gold standard, including facilitation, recognition, validation, and negotiation. Only one study has examined the overlap between language-based strategies and PCC in long-term care. Little is known about which language-based strategies support PCC in home care. Accordingly, this study investigated the overlap between language-based strategies and PCC in home care interactions. Method. Conversation analysis of 30 audio-recorded routine care interactions between home care workers and persons living with dementia was conducted. The …

Commencement Program 2022, Loma Linda University

Commencement Programs

CONTENTS

1 | Message from the President

3 | 2022 Events of Commencement

5 | The Academic Procession

6 | Institutional Administration

7 | Board of Trustees

8 | Significance of Academic Regalia

9 | University History Highlights

11 | Criteria for Institutional Awards

13 | Loma Linda University Health and Loma Linda University Honorees

27 | The Programs, The School Honorees, and The Speakers

• School of Medicine, 28
• School of Pharmacy, 52
• School of Dentistry, 67
• School of Public Health, 92
• School of Allied Health Professions - Allied Health Studies, Cardiopulmonary Sciences, Clinical Laboratory Science, Communication Sciences and Disorders, …

Can Hope Be Primed In Chronic Pain? A Clinical Application Of Health Priming, Brenda Stockdale

Educational Studies Dissertations

ABSTRACT

It is recognized that nonintentional, automatic processing shapes physical health and well-being in critical ways. Conditioning––or priming––has been shown to influence attitude, beliefs, agency, behavior, and medical outcomes. Although expectations and beliefs correlate strongly with physical health, research in clinical application is needed, and studies on hope, as related to agency, in chronic pain are rare. The purpose of this study was to investigate whether, in a chronic pain sample (N = 154), hope could be primed via a Pain Neuroscience Educational (PNE) tutorial. A pre- and post-test intervention study consisting of two randomized parallel groups was designed …

Improving The Coordination Of Care For Periprocedural Antithrombotic Medication Management In Patients Undergoing Elective Surgery, Joyce Larson

Doctor of Nursing Practice Scholarly Projects

Background: Arranging periprocedural antithrombotic medication (ATM) management is a frequently encountered complex clinical challenge. Often, there is limited time between the pre-admission clinic visit and the surgical date to coordinate ATM management and communicate the plan to the patient. This increases the risk of perioperative adverse events, case delays and cancellations, and is a patient safety concern. A quality improvement project was undertaken to address improving ATM periprocedural care coordination for patients taking ATM undergoing elective surgery. A review of the literature found clinical decision support system (CDSS) alerts to be an effective strategy. The aim of the project was …

Exploring Research Knowledge, Attitude, And Practice Of Mnri® Core Specialists, Jerzie-Ann Coppola

Seton Hall University Dissertations and Theses (ETDs)

Statement of the Problem: The Masgutova Method® is a research emergent area with a growing yet limited research base. In order to facilitate a widespread and robust acceptance and integration of The Masgutova Method® as evidence-based practice, a significant increase in research is warranted. MNRI® Core Specialists are well-positioned to be scholars in The Masgutova Method®. At this time, there is no literature exploring MNRI® Core Specialists’ foundational research knowledge, attitude toward research, and research practice.

Purpose of the Study: The purpose of this study is to establish a baseline understanding of MNRI® Core Specialists’ research knowledge, attitude, and practices. …

Development Of A Community Hospital Medicine Affiliated Inpatient Rotation For Family Medicine Residents - A Collaborative Success, David M. Gallagher, Anthony J. Viera, William E. Bynum, Poonam Sharma, John W. Ragsdale, Jeffrey Eschbach, Lalit Verma

Journal of Community Hospital Internal Medicine Perspectives

Background: Hospitalists perform key roles as inpatient educators for family medicine residents. For the past decade, Duke University Family Medicine Residency Program had its inpatient family medicine resident rotation at non-Duke facilities.

Objective: The authors describe the steps taken in 2020 to develop an inpatient Duke family medicine rotation at a North Carolina community hospital, Duke Regional Hospital, and provide outcomes data.

Methods: Duke Family Medicine Residency and Duke Regional Hospital Medicine collaborated in addressing key issues to develop an inpatient rotation for family medicine residents. Performance metrics of patients cared for by both the family medicine inpatient resident team …

Uno Student Access To Emergency Contraception: A Needs Assessment, Annika Kuchar

Theses/Capstones/Creative Projects

Emergency contraception (EC) is a common method of contraception that helps prevent ovulation before implantation of an egg inside a uterus. Among college students, EC can be utilized to prevent unplanned pregnancies that could potentially prevent someone from completing their degree. College students can face unique barriers when trying to access EC including transportation, privacy, financial, or mental/emotional barriers. The purpose of this study was to determine what barriers students at the University of Nebraska at Omaha (UNO) face when trying to access EC, and what future accommodations they would utilize if given the option. The study surveyed 147 UNO …

Comparison Of Short Chain Volatile Fatty Acids In The Breastmilk Of Normal And Overweight/Obese Mothers, Ellen Gaskill, W Andrew Clark, Kristy L. Thomas, Amy Wahlquist, Michelle E. Johnson

Undergraduate Honors Theses

INTRODUCTION: Health professionals emphasize the importance of breastfeeding in the development of children up to 6-months of age. It is known that short chain volatile fatty acids (SCVFAs) are a byproduct of nutrient fermentation by gut microbiome. These SCVFAs interact with the gut/brain axis and are known to influence infant development. Therefore, a reflection of maternal gut microbiome could likely be found in breastmilk (BM) due to diffusion of SCVFAs across the gut wall into the blood. Previous research in our laboratory has shown differences in the SCVFA fecal fermentation profile between individuals with normal (N) versus overweight/obese (OWOB) body …

Associations Of Lifestyle And Sociodemographic Factors With Dietary Supplement Use In College Students, Sydney Chratian

Senior Honors Projects

Background: Dietary supplement use has been shown to be significantly prevalent in the United States, especially among the young adult population. Studies have reported increasing use of dietary supplements among college students in the US. However, little research has investigated the sociodemographic and behavioral characteristics associated with dietary supplement use in this population.

Objectives: The aim of this study was to examine the prevalence of dietary supplement use and sociodemographic and behavioral characteristics associated with dietary supplement use in college students and examine the attitudes and beliefs of college students on dietary supplements.

Methods: A cross sectional study was conducted …

Non-Invasive Prenatal Screening (Nips) Testing Motivations And Informed Decision Making In The Low-Risk Population, Jenna Lea

Dissertations and Theses (Open Access)

Non-Invasive Prenatal Screening (NIPS) provides a risk assessment for aneuploidies by utilizing cell-free DNA (cfDNA). Recently, it was recommended that NIPS be offered to all pregnant people regardless of a priori risk for aneuploidy. In the absence of an increased risk, alternative motives for electing NIPS, such as for fetal sex disclosure, may arise and result in a less informed decision about proceeding with NIPS. Therefore, our study aimed to characterize low-risk patients’ motivations for NIPS election, compare motivations between informed and uninformed decision makers, and determine whether electing NIPS for fetal sex disclosure had any bearing on informed decision …

Adapting And Responding To A Pandemic: Patient And Family Advisory Councils In Children's Hospitals During Covid-19, Pam Dardess, Deborah L. Dokken, Ndidi I. Unaka, Jesse Hsu, Mindy Hoang, Andrew F. Beck, Beverley H. Johnson

Patient Experience Journal

This mixed-methods study investigated the effects of the COVID-19 pandemic on Patient and Family Advisory Councils (PFACs) within children’s hospitals in the United States. Specifically, the study sought to understand how PFACs adapted operations as a result of the COVID-19 pandemic, how patient and family advisors (PFAs) were engaged in the response to COVID-19, and the intersection of the COVID-19 pandemic with PFAC diversity, equity, and inclusion. The study consisted of a survey distributed to 228 children’s hospitals, with a 73% response rate, and in-depth interviews with selected survey respondents (n=12). While COVID-19 temporarily disrupted PFAC operations and forced rapid …

Book Review: The Ophthalmic Laser Handbook, William L. Miller Od, Ms, Phd

Optometric Clinical Practice

Book Review: Freisberg L, Lighthizer N, Skorin, Jr. L, Stonecipher K, and Zimmerman A. The Ophthalmic Laser Handbook. First Edition. Wolters Kluwer Health; 2021. $102.00, 350 pages, Paperback ISBN: 978-1975170172, e-book ISBN: 978-1975170219

Case Report: Bartonella Quintana-Associated Neuroretinitis, Kelly Seidler Od, Kelly A. Malloy Od

Optometric Clinical Practice

Background: Neuroretinitis is a self-limiting condition which typically causes monocular vision loss with good potential for visual recovery. It may be idiopathic or associated with infectious or inflammatory conditions which can carry systemic implications. Neuroretinitis classically presents with disc edema followed by development of a macular star pattern of exudates. It is most commonly attributed to Cat Scratch Disease, or Bartonella henselae infection. However, there have been few published reports of Bartonella quintana associated neuroretinitis.

Case Report: A 60-year-old patient presented with unilateral vision loss preceded by flu-like illness. The patient had exposure to a recently adopted cat. …