Other Medicine and Health Sciences Commons^™

Impact Of Prolonged Sitting On Cognitive Function: Implications For Cardio-Metabolic Risk, Sabina Miller

Master's Theses

Purpose: To determine if prolonged sitting negatively impacts cognitive function, cerebral perfusion, and central cardiovascular hemodynamics; and secondly, to test whether weight or physical activity status alters this response. Methods: Participants (N=20, age=26±7; BMI=30±7 kg/m²; 7 female) were taken through 3 hrs of sitting followed by a 10-min walk (treadmill). Cognitive function was assessed during sitting (10, 60, 120, and 180 mins) and following the walk using a color/word Stroop test. Cerebral perfusion was measured via near infrared spectroscopy (total hemoglobin—tHb). Central cardiovascular hemodynamics and aortic stiffness (pulse wave velocity—PWV) were measured using the SphygmoCor XCEL device before, …

An Exploration Of Barriers To Health Care Access Among Uninsured Patients: Using The Moderating Effect Of Patients’ Enablement, Enedelia L. Jessup

Electronic Theses and Dissertations

ABSTRACT On March 23, 2010, Congress passed the Patient Protection and Affordable Care Act (ACA) to increase value of care, improve clinical outcomes, decrease health care costs, and increase affordability in health care access. The purpose of the study attempts to examine the moderating effects of patient enablement impacting barriers, low socio economic status, and unmet basic needs, toward health care access in uninsured populations post ACA. Only certain aspects of patient enablement in self-management of an individual’s health care goals have been conducted with uninsured populations with barriers toward health care access. The research design was a quantitative, exploratory, …

Oregon Medicaid Expenditures After The 2014 Affordable Care Act Medicaid Expansion: Over-Time Differences Among New, Returning, And Continuously Insured Enrollees, Rachel Springer, Miguel Marino, Jean P. O'Malley, Stephan R. Lindner, Nathalie Huguet, Jennifer E. Devoe

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background—There is interest in assessing healthcare utilization and expenditures among new Medicaid enrollees after the 2014 Medicaid expansion. Recent studies have not differentiated between newly enrolled individuals and those returning after coverage gaps.

Objectives—To assess healthcare expenditures among Medicaid enrollees in the 24 months after Oregon’s 2014 Medicaid expansions and examine whether expenditure patterns were different among the newly, returning, and continuously insured.

Research Design—Retrospective cohort study using inverse-propensity weights to adjust for differences between groups.

Subjects—Oregon adult Medicaid beneficiaries insured continuously from 2014-2015 who were either newly, returning, or continuously insured.

Measures—Monthly expenditures for inpatient care, prescription drugs, total …

Uncertainty And Competing Priorities In Shared Clinical Decision-Making, Dennis J. Baumgardner

Journal of Patient-Centered Research and Reviews

In this issue introduction, the editor-in-chief of Journal of Patient-Centered Research and Reviews observes that a connecting thread among the articles published therein is an element of uncertainty among patients and clinicians. Competing priorities for the patient also may be present. Several approaches to overcoming these prevalent conflicts to delivery of better health care have been proposed, the most important of which may be clinicians embracing a will to practice shared decision-making.

Laude, Jan (Fa 1140), Manuscripts & Folklife Archives

Folklife Archives Finding Aids

Finding aid only for Folklife Archives Project 1140. Cassette recordings of the "Attunement for Healing" and "Exploring Your Dreams and ESP" conferences sponsored by the Edgar Cayce Association for Research and Enlightenment held in Virginia Beach, Virginia from 12 July 1981 to 24 July 1981. The recordings, collected by WKU folk studies graduate student Jan Laude, were used as source material for Laude’s Master’s thesis titled “A Contemporary Female Psychic: A Folkloristic Study of a Traditional Occupation,” which was published in 1982. Because the Department does not have consent forms or own copyright to these tapes, they may be used …

The Validity Of Online Patient Ratings Of Physicians, Jennifer L. Priestley, Yiyun Zhou, Robert Mcgrath

Faculty Articles

Background: Information from ratings sites are increasingly informing patient decisions related to health care and the selection of physicians.

Objective: The current study sought to determine the validity of online patient ratings of physicians through comparison with physician peer review.

Methods: We extracted 223,715 reviews of 41,104 physicians from 10 of the largest cities in the United States, including 1142 physicians listed as “America’s Top Doctors” through physician peer review. Differences in mean online patient ratings were tested for physicians who were listed and those who were not.

Results: Overall, no differences were found between the online patient ratings based …

Abstracts From The 24th Annual Health Care Systems Research Network Conference, April 11–13, 2018, Minneapolis, Minnesota

Journal of Patient-Centered Research and Reviews

Founded in 1994, the Health Care Systems Research Network (HCSRN) is a consortium of 18 research centers that are housed in community-based health systems. The organization's annual conference serves as a venue for research teams to disseminate scientific findings, stimulate new collaborations, and share insights about conducting research in real-world care-delivery settings. Abstracts accepted for presentation at HCSRN 2018 are published within this supplement of the Journal of Patient-Centered Research and Reviews.

Alumni Journal - Volume 89, Number 1, Loma Linda University School Of Medicine

Alumni Journal, School of Medicine

Features
12 | An Experience Rich in History, Beauty, and Fellowship
14 | Department Reports: Anesthesiology and Internal Medicine
22 | In Search of the Celestial
32 | APC 2018: A Preview

Departments
2 | From the Editor
5 | From the President
8 | From the Dean
9 | The Student Fund
10 | School of Medicine News
39 | Letter to AIMS Members
40 | Book Review
43 | Classified/Placement Ads
44 | Alumni News
46 | In Memoriam
50 | Historical Snapshot
51 | What's Up Doc?

Extras
4 | Board of Directors and Holding Fund Ballot …

Resource Review: 5minuteconsult, Ivan Armando Portillo

Library Articles and Research

A product review of 5MinuteConsult, an online resource from WoltersKluwer "designed to help health care professionals and clinical students by providing information that is needed at the point-of-care".

Development Of Health Rehabilitation In Mainland China: From Traditional Chinese Medicine To Modern Western Rehabilitation Methods, Michelle Moy

Independent Study Project (ISP) Collection

The aim of this study is to understand the changes occurring in China, leading to the development of health rehabilitation. This study will portray the shift of traditional Chinese medicine to modern influences of Western rehabilitation, and will also introduce the idea of an integrated model of TCM and Western Rehabilitation.

Observations were held at a TCM hospital, a rehabilitation hospital, as well as a TCM hospital that provided modern rehabilitation services. Two online questionnaire surveys were sent out to rehabilitation health professionals working in mainland China, one of which collected quantitative data while the other collected both qualitative and …

Role Of The Snf2 Homolog, Irc20, In Yeast Genome Maintenance, Deena Mohamed Galal Eldin Ahmed

Theses

In eukaryotes, DNA is wrapped around histone proteins forming a highly compact structure, the chromatin. All DNA-based processes must occur within the complex organization of the chromatin, and this requires modulation of its structure when needed. This is accomplished by covalent histone modifications that alter histone-DNA contacts, as well as through the actions of ATP-dependent chromatin remodelers. These multi-subunit complexes play major roles in transcription regulation, replication and repairing DNA damage. This thesis aims to characterize a poorly studied member of the SWI/SNF family of ATPases/helicases, Irc20, from Saccharomyces cerevisiae. Previously, Irc20 has been shown to be involved in …

The Effect Of Β-Caryophyllene On Doxorubicin-Induced Cardiotoxicity, Hasan Al-Taee

Theses

Doxorubicin is an effective and widely used chemotherapeutic drug. However, its clinical use is limited due to cardiotoxicity which it causes that appears in the form of dilated cardiomyopathy. Many efforts have been devoted to developing/discovering agents which can counter DOX-induced cardiotoxicity. The present study was undertaken to evaluate the cardioprotective potential of β Caryophyllene (BCP), a dietary phytocannabinoid, in a rat model of DOX-induced acute and chronic cardiotoxicity. BCP is widely found in various herbs and spices and is a full agonist of the cannabinoid receptor type 2 (CB₂) and exhibits potent anti-inflammatory effects. In the present …

Profiles Of Mirna Isoforms And Trna Fragments In Prostate Cancer., Rogan G. Magee, Aristeidis G. Telonis, Phillipe Loher, Eric R Londin, Isidore Rigoutsos

Computational Medicine Center Faculty Papers

MicroRNA (miRNA) isoforms ("isomiRs") and tRNA-derived fragments ("tRFs") are powerful regulatory non-coding RNAs (ncRNAs). In human tissues, both types of molecules are abundant, with expression patterns that depend on a person's race, sex and population origin. Here, we present our analyses of the Prostate Cancer (PRAD) datasets of The Cancer Genome Atlas (TCGA) from the standpoint of isomiRs and tRFs. This study represents the first simultaneous examination of isomiRs and tRFs in a large cohort of PRAD patients. We find that isomiRs and tRFs have extensive correlations with messenger RNAs (mRNAs). These correlations are disrupted in PRAD, which suggests disruptions …

Ferrocenylchalcone-Uracil Conjugates: Synthesis And Cytotoxic Evaluation, Amandeep Singh, Vishu Mehra, Neda Sadeghiani, Saghar Mozaffari, Keykavous Parang, Vipan Kumar

Pharmacy Faculty Articles and Research

Huisgen’s azide-alkyne cycloaddition reaction was employed to synthesize a series of 1H-1,2,3-triazole-tethered uracil-ferrocenyl chalcone conjugates with the aim of evaluating their in vitro anti-proliferative efficacy on human leukemia (CCRF-CEM) and human breast adenocarcinoma (MDA-MB-468) cell lines. Cytotoxic evaluation studies identified a number of synthesized conjugates that inhibited the proliferation of leukemia cancer cells by ~70% after 72 h. The selected synthesized conjugates were found to be significantly less cytotoxic against normal kidney cell line (LLC-PK1) when compared with CCRF-CEM cancer cells.

International Consensus Statement On Allergy And Rhinology: Allergic Rhinitis, Sarah K. Wise, Sandra Y. Lin, Elina Toskala, Richard R. Orlandi, Cezmi A. Akdis, Jeremiah A. Alt, Antoine Azar, Fuad M. Baroody, Claus Bachert, Helene J. Krouse

School of Medicine Publications

Background: In the 5 years that have passed since the publication of the 2018 International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR-Allergic Rhinitis 2018), the literature has expanded substantially. The ICAR-Allergic Rhinitis 2023 update presents 144 individual topics on allergic rhinitis (AR), expanded by over 40 topics from the 2018 document. Originally presented topics from 2018 have also been reviewed and updated. The executive summary highlights key evidence-based findings and recommendation from the full document.

Methods: ICAR-Allergic Rhinitis 2023 employed established evidence-based review with recommendation (EBRR) methodology to individually evaluate each topic. Stepwise iterative peer review and consensus …

Inductive And Deductive: Ambiguous Labels In Qualitative Content Analysis, Mohammad Reza Armat, Abdolghader Assarroudi, Mostafa Rad, Hassan Sharifi, Abbas Heydari

The Qualitative Report

The propounded dualism in Content Analysis as quantitative and qualitative approaches is widely supported and justified in nursing literature. Nevertheless, another sort of dualism is proposed for Qualitative Content Analysis, suggesting the adoption of "inductive" and/or "deductive" approaches in the process of qualitative data analysis. These approaches have been referred and labelled as "inductive" or "conventional"; and "deductive" or "directed" content analysis in the literature. Authors argue that these labels could be fallacious, and may lead to ambiguity; as in effect, both approaches are employed with different dominancy during the process of any Qualitative Content Analysis. Thus, authors suggest more …

Development Of Esi-Lc-Ms Method For Drug Analysis, Kimberly Yacoub

ETD Archive

Brain cancer, particularly astrocytomas, is one of the ten most common related deaths related to cancer. Temozolomide (TMZ), an oral alkylating chemotherapy drug, is used to treat anaplastic astrocytoma and glioblastoma multiforme. A few advantages of TMZ are its ability to cross the blood-brain barrier, its small size, and it is rapidly absorbed in the small intestine. Since this drug is advantageous to brain cancer patients, it is important to study the extraction of this drug. In addition, it is important to study administering this drug via microdialysis as the efficiency of the drug could increase. In mice brain tumor …

Usefulness Of The Captia Syphilis Igg Eia Test Method And Reverse Algorithm For Detection Of Syphilis Infection In A Public Health Setting, Patricia Armour

Theses and Dissertations

Syphilis, a systemic sexually transmitted disease, is on the rise in the US, with infection rates the highest recorded since 1994 according to the CDC. Useful laboratory testing is an important diagnostic tool for determining individual syphilis infection and preventing community-wide disease spread.

The purpose of this study was to determine the usefulness of a specific automated treponemal test method, the Captia^TM Syphilis IgG EIA, and the syphilis reverse algorithm interpretation for detecting syphilis infection among patients seeking care in a public health clinic. The study employed a retrospective, nonexperimental descriptive correlational design with data collected between 2012-2013 from …

The Experiences Of Undergraduate Students Of Color In The Field Of Speech-Language Pathology, Charu Dwivedi

Master's Theses and Doctoral Dissertations

This qualitative research study explored why undergraduate students of color have pursued degrees in speech-language pathology. The population of the United States consisting of individuals of color is rapidly increasing. However, the demographic of individuals of color in the field of speech-language pathology is not. Interviews with undergraduate students of color were completed to understand their journey that led them to the field. The results of the study indicated that the students of color who succeeded in getting accepted into a speech-language pathology major had support, internal motivation, and were financially stable.

Examining Injury Data Reporting Practices Among Wildland Firefighters, Erin M. Boggs

Graduate Student Theses, Dissertations, & Professional Papers

Wildland Firefighter (WLFF) Crews lack an injury surveillance program to collect information on non-traumatic and traumatic injuries. Tactical athletes including: police, military and structural firefighters all have a variety of collection systems in place for injury data collection. The lack of injury data prevents WLFF crews from identifying high-risk environments, implementing injury prevention programs, and improving the overall quality of care on the job. Over the last several decades the recent rise in wildfire occurrences and wildfire suppression costs creates a need for healthy and strong individuals in the field. The cost of firefighter salaries and medical care can be …