Optometry Commons^™

Investigation And Management Of Demodex Folliculorum Blepharitis In Clinical Practice, Orla Murphy

Doctoral

Introduction: Blepharitis is a chronic inflammatory disorder of the eyelid margin. Blepharitis patients routinely present to and are managed by optometrists and ophthalmologists in practice. Demodex folliculorum is associated with anterior blepharitis. Presently, treatment with 50% tea tree oil is recommended by the American Academy of Ophthalmology for Demodex blepharitis. However, over-the-counter products have been developed and marketed at being effective for treating Demodex blepharitis. Purpose: To examine the efficacy of over-the-counter lid hygiene products and warm compress therapy for the treatment of Demodex blepharitis. Methods: Two hundred and forty-six participants were examined at multiple visits over four studies, for …

Characterization Of Intraocular Pressure Fluctuations, Intracranial Pressure And Translaminar Pressure Measured With Wireless Telemetry In Nonhuman Primates, Jessica Violet Jasien

All ETDs from UAB

Glaucoma is the second leading cause of blindness and third leading cause of visual impairment worldwide; 180 million people suffer from a glaucomatous visual disability. Glaucoma is an ocular neurodegenerative disease with several risk factors. The major identified risk factors of glaucoma are intraocular pressure (IOP), age, race, central cornea thickness, family history, and low diastolic blood pressure. The lowering of IOP is the only modifiable risk factor for the disease. However, we know little about the true character of IOP. Periodic IOP measurements are obtained every few months or at the discretion of the clinician during office hours and …

Role Of Trib3 In Progression And Pathogenesis Of Diabetic Retinopathy, Priyamvada Milind Pitale

All ETDs from UAB

Diabetic retinopathy (DR) is reported to be one of the leading causes of blindness in the United States by Center for Disease Prevention and Control. As the estimated prevalence of the disease will likely triple by 2020, the research in this area should focus on identifying novel targets and therapeutic approaches. One of the therapeutic approaches for DR is the reprograming of retinal metabolism to delay the progression of the disease. The unfolded protein response (UPR) is recognized as a cellular pathway activated in diabetic retina which interacts with key transcription factors to physiologically regulate glucose, lipid homeostasis, and angiogenic …

A Comparison Of Dietary Intake Of Children/Adolescents With And Without Myopia, Niamh Burke, John Butler, Daniel Ian Flitcroft, James Loughman

Conference Papers

Myopia is caused by an eye which has grown too long. The prevalence of myopia has increased drastically in recent years and half of the world’s population is expected to be myopic by 2050.(1) Consequently, a significant increase in sight threatening diseases will follow.(1) Myopia most commonly develops in youth, and we now know that environmental factors affect its development. Nutritional status strongly influences growth and development, including that of the eye. It has been hypothesised, therefore, that nutrition may play a role in this excessive eye growth. Current findings are conflicted, with a clear gap in the evidence.(2,3) Therefore, …

Flash Vep In Clinically Stable Pre-Term And Full-Term Infants, Anish Kharal, Safal Khanal, Jyoti Baba Shrestha, Gauri Shankar Shrestha, Nabin Paudel

Articles

Purpose

Pre-term infants are at risk of abnormal visual development that can range from subtle to severe. The aim of this study was to compare flash VEPs in clinically stable pre-term and full-term infants at 6 months of age.

Methods

Twenty-five pre-term and 25 full-term infants underwent flash VEP testing at the age of 6 months. Monocular VEPs were recorded using flash goggles on a RETIscan system under normal sleeping conditions. Amplitude and peak time responses of the P2 component in the two eyes were averaged and compared between the two groups. Multiple regression analyses were performed to assess the …

Prevalence Of Colour Vision Deficiency In The Republic Of Ireland Schoolchildren And Associated Socio-Demographic Factors, Síofra Harrington, Peter Davison, Veronica O'Dwyer

Articles

Clinical relevance: Early screening is essential to counsel schoolchildren with congenital colour vision deficiency (CVD) in determining their future career path and to advise teachers of the impact of CVD on classroom difficulties.

Background: Congenital CVD is an X-linked genetic abnormality relatively commonplace in humans. This study aimed to determine the prevalence of congenital CVD in the Republic of Ireland schoolchildren and associated socio-demographic factors.

Methods: A total of 1,626 schoolchildren (882 boys and 744 girls), in two age groups (728 aged 6–7 years and 898 aged 12–13 years) were examined from randomly selected schools. Colour vision …

The Efficacy Of Warm Compresses In The Treatment Of Meibomian Gland Dysfunction And Demodex Folliculorum Blepharitis, Orla Murphy, Veronica O'Dwyer, Aoife Lloyd-Mckernan

Articles

Purpose: To investigate and compare the effect of warm compresses on meibomian gland dysfunction and Demodex folliculorum blepharitis.

Methods: Forty-two subjects (13 males, 29 females; mean age of 56.45 years) enrolled and completed the two-month warm compress treatment study. Three warm compress therapies were compared: Warm face cloth, MGDRx EyeBag® and OPTASETM Moist Heat Mask. Subjects attended for four visits: baseline, two weeks, four weeks, and eight weeks. Subjective symptoms, osmolarity, non-invasive tear break-up time, ocular surface staining, Schirmer I test, meibum expressibility and clarity, and eyelash manipulation and epilation to assess for the presence of Demodex folliculorum, …

Optimising Subjective Anterior Eye Grading Precision, Marta Vianya-Estopa, Manbir Nagra, Arnold Cochrane Arnold Cochrane, Neil Retallic Neil Retallic, Dean Dunning, Louise Terry Louise Terry, Aoife Lloyd, James Wolffsohn

Articles

To establish the optimum grading increment which ensured parity between practitioners while maximising clinical precision.

Raman Spectroscopy For The Discrimination Of Autoimmune Disorders, Neha Chaudhary

Doctoral

The bidirectional cooperativity between the innate and adaptive arm of the immune network in response to foreign invaders has long been accepted. Under normal circumstances this response is very effective at eliminating infection, however, inappropriate activation triggered by self components is observed in autoimmune conditions such as Systemic Lupus Erythematosus (SLE) and Rheumatoid Arthritis (RA). Due to the overlapping nature of the symptoms of each of the syndromes, in terms of clinical and laboratory manifestations, and the lack of a single marker predictive methodology, the differential diagnosis and treatment of these patients still proves challenging. With the advent of targeted …

Holographic Sensors For The Detection Of Liquid Phase Analytes, Sabad-E Gul

Doctoral

The aim of this project is to design, fabricate and study experimentally photonic structures created by holographic lithography for application in sensing. The aim is to modify the photonic structures with analyte sensitive materials and view of their application in environmental and biomedical sensing. Two types of photonic structures were investigated in these studies: modified surface relief holographic gratings and volume holographic gratings.

Quality Improvement Initiative To Increase Comprehensive Eye Exams In Patients With Diabetes, Julia Khoury

Doctor of Nursing Practice

Diabetic retinopathy is the most common microvascular complication associated with poorly controlled diabetes. Yet, only 60% of the diabetic population receives an annual eye examination by an eye specialist. Retinal imaging increases surveillance of retinopathy, however, it does not take the place of a comprehensive eye examination by an ophthalmologist or optometrist. The aim of this quality improvement project was to increase comprehensive eye examinations in patients with diabetes aged 18 to 75 years in a family practice that recently purchased a retinal imager. This quality improvement project occurred over a 10-week period. Project objectives included increasing comprehensive dilated eye …

Hierarchy Of Evidence [Eps File], Judy Schmitt

Library Faculty Works

Hierarchy of Evidence showing primary and secondary sources

Welcome Readers, Barbara Aranda-Naranjo, Phd

Optometric Clinical Practice

Interim provost would like to welcome you as readers to our new journal, Optometric Clinical Practice.

Welder’S Maculopathy; A Case Report, Christina E. Morettin Od, Bruce A. Teitelbaum Od

Optometric Clinical Practice

Background: Outer retinal damage can occur when excessive ultraviolet (UV) radiation reaches the retina. The most common etiology is from the sun, known as solar retinopathy, especially when individuals observe solar eclipses without appropriate eye protection. Another cause of UV retinopathy that is not frequently encountered in practice is arc welding, causing Welder’s Maculopathy. Fortunately, the prognosis of the UV retinopathies is quite favourable, as many fully recover after the initial insult to the retina. This retrospective case review aims to outline the clinical manifestation of this maculopathy and current opinions on its etiology and diagnosis.

Case Report: A 45-year-old …

Presumed Diffuse Unilateral Subacute Neuroretinitis: A Review Supported By A Unique Case, Kirsti K. Ramirez Od, Joseph Pizzimenti Od, Jeannette Wong-Powell Od, Jeffrey Rabin Od

Optometric Clinical Practice

Diffuse unilateral subacute neuroretinitis (DUSN) is a rare, sight-threatening inflammatory condition caused by a nematode. It typically affects healthy children and young adults. Various nematodes have been implicated, including those that originate from dogs and raccoons. Late stage findings include optic nerve atrophy, retinal arterial attenuation, “retinitis pigmentosa-like” retinal pigmentary changes, and central and peripheral vision loss. We present a case study of long-standing DUSN. The combination of optical coherence tomography (OCT) and visual electrophysiology testing proved invaluable in establishing a presumptive diagnosis of this rare condition.

Anterior Subcapsular Cataract Secondary To Black Mold Exposure, Katherine B. Lynch Od, Bruce A. Teitelbaum Od

Optometric Clinical Practice

A case report of a 31-year-old woman who developed anterior subacapsular cataracts, and associated dermatological signs, after exposure to black mold. While atopic illness is commonly seen in childhood, a growing body of literature supports adult onset atopic dermatitis. Anterior subcapsular cataracts are pathognomonic for atopic illness, and can support a definitive and expedited dermatologic diagnosis of adult onset disease.

Inaugural Editorial, Paul B. Freeman Od

Optometric Clinical Practice

Letter from the Editor-in-Chief

Welcome Letter Of Introduction To Our New Journal - Optometric Clinical Practice, Timothy Wingert Od

Optometric Clinical Practice

On behalf of the entire editorial board, Timothy Wingert, OD, dean at the University of the Incarnate Word - Rosenberg School of Optometry, welcomes you to the inaugural issue of Optometric Clinical Practice. (ISSN: 2575-7717)

Low-Dose (0.01%) Atropine Eye Drops To Reduce Progression Of Myopia In Children: A Multi-Centre Placebo- Controlled Randomised Trial In The United Kingdom (Champ- Uk) – Study Protocol., Augusto Azuara-Blanco, Nicola Logan, Niall Strang, Peter Allen, Ruth Hogg, Ruth Weir, Paul Doherty, Catherine Adams, Margaret Mcfarland, Evie Gardner, Rejina Verghis, Jennifer Preston, James Loughman, Daniel I. Flintcroft, David Mackey, Samantha Lee, Christopher Hammond, Nathan Congdon, Mike Clarke

Articles

Background/aims To report the protocol of a trial designed to evaluate the efficacy, safety and mechanism of action of low-dose atropine (0.01%) eye-drops for reducing progression of myopia in UK children. Methods Multicentre, double-masked, superiority, placebo-controlled, randomised trial. We will enrol children aged 6–12 years with myopia of −0.50 dioptres or worse in both eyes. We will recruit 289 participants with an allocation ratio of 2:1 (193 atropine; 96 placebo) from five centres. Participants will instil one drop in each eye every day for 2 years and attend a research centre every 6 months. The vehicle and preservative will be …

Association Of Total Zinc Intake With Myopia In U.S. Children And Adolescents, Niamh Burke, John Butler, Daniel Ian Flitcroft, Daniel Mccartney, James Loughman

Articles

Significance: This present study advances our knowledge on the role of lifestyle factors in myopia (short-sightedness), specifically dietary factors. It has been suggested in previous studies that lower zinc status is associated with myopia; however, this article shows no relationship between dietary zinc intake and myopia in U.S. adolescents. Purpose: It has been suggested that low zinc levels may contribute to the development of myopia. The aim of the present study is to examine, for the first time in a Western population, the association of total dietary and supplement zinc intake with myopia. Methods: A total of 1095 children/adolescents aged …