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Nervous System Diseases Commons

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1,435 full-text articles. Page 65 of 66.

Care Versus Cure: We Can Progress In Both, Kenneth P. Serbin 2010 University of San Diego

Care Versus Cure: We Can Progress In Both, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Tetrahydroisoquinoline Neurotoxins In Parkinson Disease, Michael G. DeCuypere 2010 University of Tennessee Health Science Center

Tetrahydroisoquinoline Neurotoxins In Parkinson Disease, Michael G. Decuypere

Theses and Dissertations (ETD)

The goal of this dissertation work was to (1) determine the distribution of several tetrahydroisoquinoline (TIQ) derivatives in rodent, normal human and Parkinson disease (PD) brain, (2) quantify the levels of these TIQ derivatives in common food sources in an effort to link specific food intake patterns with the development of PD and (3) examine the neurotoxicity of select TIQ derivatives in human dopaminergic cell culture. The TIQs are a family of monoamine alkaloids that share structural homology with 1-methyl-4-phenyl-1,2,3,6-tetrahyrdropyridine (MPTP), can be formed from dopamine or its oxidized metabolites and may be involved in the pathogenesis of monoaminergic cell …


Pain Management In Nursing Home Residents With Cancer And Dementia With And Without Hospice Services, Todd Bryant Monroe 2010 University of Tennessee Health Science Center

Pain Management In Nursing Home Residents With Cancer And Dementia With And Without Hospice Services, Todd Bryant Monroe

Theses and Dissertations (ETD)

Aims: We sought to identify differences in pain management between two groups; nursing home residents with malignant cancer and dementia with and without hospice services.

Methods: Decedent records from 2003-2009 were assessed for diagnosis of dementia and cause of death as cancer. Ten malignant cancer diagnoses were determined a priori from the CDC 2004 data on the top 10 malignant cancers for all races and genders. Fifty-five decedents from 10 nursing homes were included in the final sample. Four instruments were used: Minimum Data Set (MDS) a standardized assessment tool required of most U.S. nursing homes. A large …


Eye Movement Measures Of Cognitive Control In Children With Tourette Syndrome, Cameron B. Jeter 2010 University of Texas Graduate School of Biomedical Sciences at Houston

Eye Movement Measures Of Cognitive Control In Children With Tourette Syndrome, Cameron B. Jeter

Dissertations & Theses (Open Access)

Tourette Syndrome begins in childhood and is characterized by uncontrollable repetitive actions like neck craning or hopping and noises such as sniffing or chirping. Worst in early adolescence, these tics wax and wane in severity and occur in bouts unpredictably, often drawing unwanted attention from bystanders. Making matters worse, over half of children with Tourette Syndrome also suffer from comorbid, or concurrent, disorders such as attention deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD). These disorders introduce anxious thoughts, impulsivity, inattention, and mood variability that further disrupt children with Tourette Syndrome from focusing and performing well at school and home. …


Ten Reasons To Cure Hd, Kenneth P. Serbin 2010 University of San Diego

Ten Reasons To Cure Hd, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


The Point Of No Return, Kenneth P. Serbin 2010 University of San Diego

The Point Of No Return, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Impact Of Insurance Status On Migraine Care In The United States, Andrew Wilper, Steffie Woolhandler, David U. Himmelstein, Rachel Nardin 2010 United States Department of Veterans Affairs

Impact Of Insurance Status On Migraine Care In The United States, Andrew Wilper, Steffie Woolhandler, David U. Himmelstein, Rachel Nardin

Publications and Research

Objective
To determine whether insurance status is associated with differential outpatient treatment of migraine in the United States.

Methods
We analyzed 11 years of data from the National Ambulatory Medical Care Survey and National Hospital Ambulatory Medical Care Survey (1997–2007), which survey patient visits to doctors’ offices, hospital outpatient departments, and emergency departments (EDs) in the United States. We used logistic regression to determine whether insurance status was associated with the prescription of standard migraine therapy, defined as 1) a triptan or dihydroergotamine and 2) a prophylactic agent.

Results
We identified 6,814 individual patient visits for migraine, representing 68.6 million …


Growing Burden Of Neurological Diseases In Pakistan � Need For A National Health Survey, Mohammad Wasay, Shaukat Ali 2010 Aga Khan University

Growing Burden Of Neurological Diseases In Pakistan � Need For A National Health Survey, Mohammad Wasay, Shaukat Ali

Department of Medicine

No abstract provided.


Band Heterotopia, M. S. Alam, N Naila 2010 Aga Khan University

Band Heterotopia, M. S. Alam, N Naila

Section of Internal Medicine

Band heterotopias are one of the rarest groups of congenital disorder that result in variable degree of structural abnormality of brain parenchyma. Band of heterotopic neurons result from a congenital or acquired deficiency of the neuronal migration. MRI is the examination of choice for demonstrating these abnormalities because of the superb gray vs. white matter differentiation, detail of cortical anatomy and ease of multiplanar imaging. We report a case of band heterotopia that showed a bilateral band of gray matter in deep white matter best demonstrated on T2 Wt. and FLAIR images.


Good-Bye, Pre-Existing Conditions!, Kenneth P. Serbin 2010 University of San Diego

Good-Bye, Pre-Existing Conditions!, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Aiming For Hd Clinical Trials, Kenneth P. Serbin 2010 University of San Diego

Aiming For Hd Clinical Trials, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


A Restless Soul At The Hd Research Meeting, Kenneth P. Serbin 2010 University of San Diego

A Restless Soul At The Hd Research Meeting, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


A Super Sunday Hd Story, Kenneth P. Serbin 2010 University of San Diego

A Super Sunday Hd Story, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Telling The Truth About A Disease, Kenneth P. Serbin 2010 University of San Diego

Telling The Truth About A Disease, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


When The Pain Brings A Smile, Kenneth P. Serbin 2010 University of San Diego

When The Pain Brings A Smile, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


Squeezing In The Life, Kenneth P. Serbin 2010 University of San Diego

Squeezing In The Life, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.


An Epitope From Acanthamoeba Castellanii That Cross-React With Proteolipid Protein 139-151-Reactive T Cells Induces Autoimmune Encephalomyelitis In Sjl Mice, Chandirasegaran Massilamany, David Steffan, Jay Reddy 2010 University of Nebraska-Lincoln

An Epitope From Acanthamoeba Castellanii That Cross-React With Proteolipid Protein 139-151-Reactive T Cells Induces Autoimmune Encephalomyelitis In Sjl Mice, Chandirasegaran Massilamany, David Steffan, Jay Reddy

Jay Reddy Publications

We report here that an epitope (aa, 83-95) derived from Acanthamoeba castellanii (ACA) induces clinical signs of experimental autoimmune encephalomyelitis (EAE) in SJL/J mice reminiscent of the disease induced with myelin proteolipid protein (PLP) 139-151. By using IAs/tetramers, we demonstrate that both ACA 83-95 and PLP 139-151 generate antigen-specific cross-reactive CD4 T cells and the T cells secrete identical patterns of cytokines and induce EAE with a similar severity. These results may provide insights into the pathogenesis of multiple sclerosis and ACA-induced granulomatous encephalitis.


An Integrated Modeling Method For Bone Strain Analysis, Daniel Leib, Henry Wang, Eric Dugan 2010 Boise State University

An Integrated Modeling Method For Bone Strain Analysis, Daniel Leib, Henry Wang, Eric Dugan

Daniel Leib

No abstract provided.


An Integrated Modeling Method For Tibia Strain Analysis, Daniel Leib, Henry Wang 2010 Boise State University

An Integrated Modeling Method For Tibia Strain Analysis, Daniel Leib, Henry Wang

Daniel Leib

No abstract provided.


Muscular Fatigue Increases Ground Reaction Loading Rate During Walking, Henry Wang, Jeff Frame, Elicia Ozimek, Cara Reedstrom, Daniel Leib, Eric Dugan 2010 Ball State University

Muscular Fatigue Increases Ground Reaction Loading Rate During Walking, Henry Wang, Jeff Frame, Elicia Ozimek, Cara Reedstrom, Daniel Leib, Eric Dugan

Daniel Leib

No abstract provided.


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